Pub Date : 2018-06-30DOI: 10.23937/2469-5807/1510064
Al-Din Mohammed
Objectives: Cutting injuries and needle-stick injuries constitute a potentially fatal danger to pathologists. We evaluated such injuries in four french university anatomic pathology laboratories and analyzed the effect of the using of cut-resistant gloves to prevent these injuries. Methods: For this study, we designed a 12-item online survey to assess the location of the laboratory, the number of years of practice, detailed questions about the use of cut-resistant glove including: Weather the pathologist started using them before or after his residency, frequency of wearing it, on which hand he or she wear it, History of hand-cut injuries with detailed information about the affected hand and the moment of the accident, Declaration of the accident and weather blood tests for infectious diseases such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) were done. Results: 17 of the 42 pathologists who participated in our study were sustained a hand injury. Most injuries were located at the non-dominant hand. Only 3 of 17 pathologists were wearing a cut-resistant glove when the injury happened, and those injuries turned to be a needle-stick injury caused by the tip of the blade or by a pin. Conclusion: Cut-resistant protective gloves are an effective and cost-effective completion of personal occupational safety measures in surgical pathology. We strongly recommend the use of such gloves, especially when handling a fresh surgical specimen.
{"title":"Assessment of Hand-Cut Injuries among Pathologists and the Efficacy of Cut-Resistant Gloves in Preventing Them","authors":"Al-Din Mohammed","doi":"10.23937/2469-5807/1510064","DOIUrl":"https://doi.org/10.23937/2469-5807/1510064","url":null,"abstract":"Objectives: Cutting injuries and needle-stick injuries constitute a potentially fatal danger to pathologists. We evaluated such injuries in four french university anatomic pathology laboratories and analyzed the effect of the using of cut-resistant gloves to prevent these injuries. Methods: For this study, we designed a 12-item online survey to assess the location of the laboratory, the number of years of practice, detailed questions about the use of cut-resistant glove including: Weather the pathologist started using them before or after his residency, frequency of wearing it, on which hand he or she wear it, History of hand-cut injuries with detailed information about the affected hand and the moment of the accident, Declaration of the accident and weather blood tests for infectious diseases such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) were done. Results: 17 of the 42 pathologists who participated in our study were sustained a hand injury. Most injuries were located at the non-dominant hand. Only 3 of 17 pathologists were wearing a cut-resistant glove when the injury happened, and those injuries turned to be a needle-stick injury caused by the tip of the blade or by a pin. Conclusion: Cut-resistant protective gloves are an effective and cost-effective completion of personal occupational safety measures in surgical pathology. We strongly recommend the use of such gloves, especially when handling a fresh surgical specimen.","PeriodicalId":444147,"journal":{"name":"International Journal of Pathology and Clinical Research","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130269079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.23937/2469-5807/1510067
Easwar Arti, M. Dion, Ligato Saverio
Duodenal gangliocytic paraganglioma (DGP) is a rare neoplasm usually found in the second portion of the duodenum and comprised of epithelioid neuroendocrine cells, Schwann cell-like spindle cells, and ganglion cells. We report a case of a 58-year-old male with a duodenal mass discovered incidentally during a staging PET scan for an oropharyngeal carcinoma. An ultrasound-guided fine needle aspirate (FNA) of the lesion revealed fascicles of spindle cells and sparse epithelioid cells with mild cytological atypia. Cell-block prepared from this specimen showed fragments of tightly packed clusters of spindle cells positive for S-100 and Sox 10. A diagnosis of a spindle cell neoplasm, favoring a schwannoma, was rendered. Subsequent surgical resection of this 2.8 cm submucosal mass showed predominantly spindled Schwann-like cells, interspersed epithelioid cells, rare ganglion cells, and an immunohistochemical profile that confirmed the diagnosis of DGP. On retrospective review of the prior aspirate, rare Neurofilament protein (NFP) positive ganglion cells were also identified and thus concluded to be consistent with DGP. Although two case reports of DGP, both with regional metastatic lymph nodal disease, have been previously described in the English language literature, this is the first case report describing the cytological features of a DGP without evidence of lymph node metastasis. In conclusion, in the evaluation of submucosal duodenal lesions by US-guided FNA, the possibility of a DGP should be included in the differential diagnosis when two or all three cell elements required for this diagnosis are identified and their phenotype is confirmed by immunohistochemical markers. spindle cells, and ganglion-like cells. Although most commonly found in the second part of the duodenum, with a predilection for the periampullary region, rare cases with involvement of the jejunum, pylorus, esophagus, pancreas, appendix, and lung have also been reported in the literature [1]. DGP is generally considered a benign lesion, however, metastasis to regional lymph nodes or rarely to other organs, including one case with bone metastasis and two with liver metastasis, have also been reported in approximately 5-7% of cases [28]. Most cases are diagnosed on surgical resection, and to our knowledge, only two case reports describing the cytological features of DGP have been reported in the English language literature [6,8]. Interestingly, both cases were associated with metastasis to locoregional lymph nodes. Herein, we present the cytological features of a new case of DGP presenting as a solitary submucosal mass without evidence of lymph node metastasis. In addition, we will discuss the differential diagnosis with other submucosal duodenal lesions, and the limitations that sometimes may preclude its diagnosis on US-guided FNA.
{"title":"Cytological Diagnosis of Duodenal Gangliocytic Paraganglioma on Ultrasound-Guided Fine Needle Aspirate: A Case Report with Review of the Literature","authors":"Easwar Arti, M. Dion, Ligato Saverio","doi":"10.23937/2469-5807/1510067","DOIUrl":"https://doi.org/10.23937/2469-5807/1510067","url":null,"abstract":"Duodenal gangliocytic paraganglioma (DGP) is a rare neoplasm usually found in the second portion of the duodenum and comprised of epithelioid neuroendocrine cells, Schwann cell-like spindle cells, and ganglion cells. We report a case of a 58-year-old male with a duodenal mass discovered incidentally during a staging PET scan for an oropharyngeal carcinoma. An ultrasound-guided fine needle aspirate (FNA) of the lesion revealed fascicles of spindle cells and sparse epithelioid cells with mild cytological atypia. Cell-block prepared from this specimen showed fragments of tightly packed clusters of spindle cells positive for S-100 and Sox 10. A diagnosis of a spindle cell neoplasm, favoring a schwannoma, was rendered. Subsequent surgical resection of this 2.8 cm submucosal mass showed predominantly spindled Schwann-like cells, interspersed epithelioid cells, rare ganglion cells, and an immunohistochemical profile that confirmed the diagnosis of DGP. On retrospective review of the prior aspirate, rare Neurofilament protein (NFP) positive ganglion cells were also identified and thus concluded to be consistent with DGP. Although two case reports of DGP, both with regional metastatic lymph nodal disease, have been previously described in the English language literature, this is the first case report describing the cytological features of a DGP without evidence of lymph node metastasis. In conclusion, in the evaluation of submucosal duodenal lesions by US-guided FNA, the possibility of a DGP should be included in the differential diagnosis when two or all three cell elements required for this diagnosis are identified and their phenotype is confirmed by immunohistochemical markers. spindle cells, and ganglion-like cells. Although most commonly found in the second part of the duodenum, with a predilection for the periampullary region, rare cases with involvement of the jejunum, pylorus, esophagus, pancreas, appendix, and lung have also been reported in the literature [1]. DGP is generally considered a benign lesion, however, metastasis to regional lymph nodes or rarely to other organs, including one case with bone metastasis and two with liver metastasis, have also been reported in approximately 5-7% of cases [28]. Most cases are diagnosed on surgical resection, and to our knowledge, only two case reports describing the cytological features of DGP have been reported in the English language literature [6,8]. Interestingly, both cases were associated with metastasis to locoregional lymph nodes. Herein, we present the cytological features of a new case of DGP presenting as a solitary submucosal mass without evidence of lymph node metastasis. In addition, we will discuss the differential diagnosis with other submucosal duodenal lesions, and the limitations that sometimes may preclude its diagnosis on US-guided FNA.","PeriodicalId":444147,"journal":{"name":"International Journal of Pathology and Clinical Research","volume":"248 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123075208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.23937/2469-5807/1510135
Chisholm Cary, Hatch Michael, P. Sage, Chain Sage
{"title":"PRAME Expression in Mimickers of Melanoma in Situ: Paget's Disease, Extramammary Paget's Disease, and Pagetoid Squamous Cell Carcinoma In Situ","authors":"Chisholm Cary, Hatch Michael, P. Sage, Chain Sage","doi":"10.23937/2469-5807/1510135","DOIUrl":"https://doi.org/10.23937/2469-5807/1510135","url":null,"abstract":"","PeriodicalId":444147,"journal":{"name":"International Journal of Pathology and Clinical Research","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126605993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.23937/2469-5807/1510130
Lee Jenna, Puyana Carolina, Liu Wenhua, Dimitropoulous Vassilios, H. Roger
{"title":"Hidradenocarcinoma Treated with Mohs Surgery","authors":"Lee Jenna, Puyana Carolina, Liu Wenhua, Dimitropoulous Vassilios, H. Roger","doi":"10.23937/2469-5807/1510130","DOIUrl":"https://doi.org/10.23937/2469-5807/1510130","url":null,"abstract":"","PeriodicalId":444147,"journal":{"name":"International Journal of Pathology and Clinical Research","volume":"519 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116251444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Congenital pulmonary airway malformations (CPAMs) consist of a spectrum of cystic or non-cystic lung malformations often associated with bronchial atresia during in utero development. Several classifications for these lesions have been proposed using radiologic or pathologic criteria based on cyst size and histology, with the Stocker classification being perhaps the most commonly used in the pathology literature. However, those classifications of CPAM have relied predominantly on observations made in either postnatal lung resections or stillborn infants at autopsy and generally not applicable to prenatally resected CPAMs. We present a case of CPAM with intra-lobar sequestration in a 15 weeks old fetus. To the best of our knowledge, it is the first case reported in such an early developmental stage. There were some difficulties in classifying it due to limited pathologic classification schemes suitable for fetal lungs. More pathologic studies of pulmonary malformations occurring during the fetal period are required to highlight the variability of findings seen in such lesions at all developmental stages.
{"title":"Congenital Cystic Pulmonary Airway Malformation with Intralobar Sequestration in 15 Weeks Old Fetus- Peculiarity of Early Developmental Stage","authors":"Kozlova Daria, Perlman Sharon, Birnbaum Roee, Mayer Ori, Gilboa Yinon","doi":"10.23937/2469-5807/1510136","DOIUrl":"https://doi.org/10.23937/2469-5807/1510136","url":null,"abstract":"Congenital pulmonary airway malformations (CPAMs) consist of a spectrum of cystic or non-cystic lung malformations often associated with bronchial atresia during in utero development. Several classifications for these lesions have been proposed using radiologic or pathologic criteria based on cyst size and histology, with the Stocker classification being perhaps the most commonly used in the pathology literature. However, those classifications of CPAM have relied predominantly on observations made in either postnatal lung resections or stillborn infants at autopsy and generally not applicable to prenatally resected CPAMs. We present a case of CPAM with intra-lobar sequestration in a 15 weeks old fetus. To the best of our knowledge, it is the first case reported in such an early developmental stage. There were some difficulties in classifying it due to limited pathologic classification schemes suitable for fetal lungs. More pathologic studies of pulmonary malformations occurring during the fetal period are required to highlight the variability of findings seen in such lesions at all developmental stages.","PeriodicalId":444147,"journal":{"name":"International Journal of Pathology and Clinical Research","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133157670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.23937/2469-5807/1510129
Braham Emna, Sassi Farah, Abdennadh Mehdi, M. Mona, E. M. Faouzi
{"title":"Primary Pulmonary Colloid Adenocarcinoma: A Case Report with Literature Review","authors":"Braham Emna, Sassi Farah, Abdennadh Mehdi, M. Mona, E. M. Faouzi","doi":"10.23937/2469-5807/1510129","DOIUrl":"https://doi.org/10.23937/2469-5807/1510129","url":null,"abstract":"","PeriodicalId":444147,"journal":{"name":"International Journal of Pathology and Clinical Research","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130440564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.23937/2469-5807/1510132
Middleton Lavinia P, Wang Jing
{"title":"Basal-Like Atypical Ductal Hyperplasia and Basal-Like Ductal Carcinoma In Situ: Evidence for Precursor of Basal-Like Breast Cancer","authors":"Middleton Lavinia P, Wang Jing","doi":"10.23937/2469-5807/1510132","DOIUrl":"https://doi.org/10.23937/2469-5807/1510132","url":null,"abstract":"","PeriodicalId":444147,"journal":{"name":"International Journal of Pathology and Clinical Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125416199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.23937/2469-5807/1510144
Alkhattaf Ibtisam
{"title":"Recurrent Kaposi Sarcoma in an HIV-Seronegative Saudi Man: A Case Report and Literature Review","authors":"Alkhattaf Ibtisam","doi":"10.23937/2469-5807/1510144","DOIUrl":"https://doi.org/10.23937/2469-5807/1510144","url":null,"abstract":"","PeriodicalId":444147,"journal":{"name":"International Journal of Pathology and Clinical Research","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133745192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：