Pub Date : 2024-12-20eCollection Date: 2024-10-01DOI: 10.1055/s-0044-1795168
Dale Dangleben
{"title":"Bridging the Technological Divide in Medicine: A Global Responsibility.","authors":"Dale Dangleben","doi":"10.1055/s-0044-1795168","DOIUrl":"https://doi.org/10.1055/s-0044-1795168","url":null,"abstract":"","PeriodicalId":44614,"journal":{"name":"Surgery Journal","volume":"10 4","pages":"e60-e61"},"PeriodicalIF":0.8,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Colonic obstruction is reported in 85% of emergency colorectal surgery for cancer. Colonic ischemia, however, is a rare entity and is found in 5% of these emergency cases. We herein present the case of a 72-year-old man presenting with signs and symptoms of obstruction and was found to have an obstructive sigmoid cancer. A first urgent laparotomy showed small bowel ischemia, for which small bowel resection and large bowel decompression were done without tumor resection. Postoperatively, the patient transiently improved, then deteriorated in few days, and a second urgent laparotomy showed a large bowel ischemia proximal to the mass. The treatment for patients with colon cancer with suspected colonic ischemia should be emergency laparotomy with long abdominal incision, carefully exploring the whole length of the small and large bowel. Despite large bowel decompression, a secondary colonic ischemic event should be suspected in case of deterioration.
{"title":"Two Separate Small and Large Ischemic Bowel Events Secondary to Sigmoid Adenocarcinoma: A Case Report.","authors":"Alamir-Noureddine AlAyoubi, Souad Ghattas, Hani Maalouf, Georges Chahine, Kiril Kiriakos, Mirna Fares","doi":"10.1055/s-0044-1800978","DOIUrl":"10.1055/s-0044-1800978","url":null,"abstract":"<p><p>Colonic obstruction is reported in 85% of emergency colorectal surgery for cancer. Colonic ischemia, however, is a rare entity and is found in 5% of these emergency cases. We herein present the case of a 72-year-old man presenting with signs and symptoms of obstruction and was found to have an obstructive sigmoid cancer. A first urgent laparotomy showed small bowel ischemia, for which small bowel resection and large bowel decompression were done without tumor resection. Postoperatively, the patient transiently improved, then deteriorated in few days, and a second urgent laparotomy showed a large bowel ischemia proximal to the mass. The treatment for patients with colon cancer with suspected colonic ischemia should be emergency laparotomy with long abdominal incision, carefully exploring the whole length of the small and large bowel. Despite large bowel decompression, a secondary colonic ischemic event should be suspected in case of deterioration.</p>","PeriodicalId":44614,"journal":{"name":"Surgery Journal","volume":"10 4","pages":"e65-e70"},"PeriodicalIF":0.8,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-12eCollection Date: 2024-10-01DOI: 10.1055/s-0044-1800917
ElMuhtadi B Y Gasoma, Mohamed A Marouf
Background Globally, surgical care plays a vital role in health care. Unfortunately, complications arise in approximately 5 to 18% of surgical procedures. However, research has shown that following the surgical safety checklist provided by the World Health Organization (WHO) can significantly reduce these complications and surgery-related fatalities. The objective of this study was to assess the accuracy and completion of the WHO Surgical Safety Checklist. Materials and Method From October 3, 2022 to February 28, 2023, a comprehensive observational study was conducted involving 300 patients who underwent elective and emergency surgeries. The completion rates for the different stages of surgery, namely sign-in, time-out, and sign-out, were determined using the SPSS 22.0 software. Result In our research, we specifically examined the completion of the checklist for 300 patients who underwent important procedures within a span of 5 months. For each patient, we ensured that their identities, procedures, and consent were verified with a 100% success rate. Additionally, we thoroughly checked the anesthesia equipment and drugs for safety in every case. Furthermore, all essential images were consistently displayed for each patient, achieving a 100% adherence to this crucial aspect of the process. Conclusion In general, the level of completeness of the checklist was satisfactory across the sign-in, time-out, and sign-out phases. While this study did not assess the specific outcomes, it is presumed that incomplete data may have exposed patients to potential perioperative complications.
{"title":"Enhancing Surgical Outcomes: Evaluating the Impact of Implementing the World Health Organization Surgical Safety Checklist-A Prospective Cross-Sectional Study.","authors":"ElMuhtadi B Y Gasoma, Mohamed A Marouf","doi":"10.1055/s-0044-1800917","DOIUrl":"10.1055/s-0044-1800917","url":null,"abstract":"<p><p><b>Background</b> Globally, surgical care plays a vital role in health care. Unfortunately, complications arise in approximately 5 to 18% of surgical procedures. However, research has shown that following the surgical safety checklist provided by the World Health Organization (WHO) can significantly reduce these complications and surgery-related fatalities. The objective of this study was to assess the accuracy and completion of the WHO Surgical Safety Checklist. <b>Materials and Method</b> From October 3, 2022 to February 28, 2023, a comprehensive observational study was conducted involving 300 patients who underwent elective and emergency surgeries. The completion rates for the different stages of surgery, namely sign-in, time-out, and sign-out, were determined using the SPSS 22.0 software. <b>Result</b> In our research, we specifically examined the completion of the checklist for 300 patients who underwent important procedures within a span of 5 months. For each patient, we ensured that their identities, procedures, and consent were verified with a 100% success rate. Additionally, we thoroughly checked the anesthesia equipment and drugs for safety in every case. Furthermore, all essential images were consistently displayed for each patient, achieving a 100% adherence to this crucial aspect of the process. <b>Conclusion</b> In general, the level of completeness of the checklist was satisfactory across the sign-in, time-out, and sign-out phases. While this study did not assess the specific outcomes, it is presumed that incomplete data may have exposed patients to potential perioperative complications.</p>","PeriodicalId":44614,"journal":{"name":"Surgery Journal","volume":"10 4","pages":"e53-e59"},"PeriodicalIF":0.8,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11637733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-12eCollection Date: 2024-10-01DOI: 10.1055/s-0044-1792126
Darin T Johnston, David B Powers, Matthew G Hartwig, Russel R Kahmke, Linda C Cendales
Objective To summarize patient characteristics and outcomes for the historical and current methods of long-segment tracheal replacement in humans. Materials and Methods A single reviewer screened the abstracts and full texts using Covidence for file management. Studies published in English that reported human subjects with circumferential or near-circumferential (>270 degrees) cervical tracheal replacements were included. Articles with subjects treated with primary anastomosis alone, retracted articles, abstracts, expert opinion articles, and conference presentations were excluded. Results A total of 32 articles were included in the review reporting 156 cases of long-segment tracheal replacement including synthetic (alive at 1-8 years n = 6/64), regenerative medicine (dead at 15 days-55 months n = 4, not reported n = 6), cadaveric tracheal allograft (alive at 5 months-10 years n = 32/38), aortic allograft (alive at 6-85 months n = 12/16), free tissue transfer (alive at 6-108 months n = 13/21), allotransplantation (alive at 6-24 months n = 5/8), and vascular composite allograft (VCA) (alive at 20 months n = 1/1). Conclusion Silicone and Marlex prostheses have poor long-term outcomes. The cadaveric tracheal allograft can only replace near-circumferential tracheal defects and is therefore limited to benign tracheal pathology. Inadequate structural support plagues the aortic allograft and often requires numerous invasive procedures and maintenance of an intraluminal stent. A lack of mucociliary clearance exists in all methods of tracheal replacement except cadaveric tracheal allograft and VCA and can cause fatal mucous plugging and chronic pulmonary infections. VCA and allotransplantation require long-term immunomodulation therapy.
{"title":"Tracheal Replacement: A Scoping Review.","authors":"Darin T Johnston, David B Powers, Matthew G Hartwig, Russel R Kahmke, Linda C Cendales","doi":"10.1055/s-0044-1792126","DOIUrl":"10.1055/s-0044-1792126","url":null,"abstract":"<p><p><b>Objective</b> To summarize patient characteristics and outcomes for the historical and current methods of long-segment tracheal replacement in humans. <b>Materials and Methods</b> A single reviewer screened the abstracts and full texts using Covidence for file management. Studies published in English that reported human subjects with circumferential or near-circumferential (>270 degrees) cervical tracheal replacements were included. Articles with subjects treated with primary anastomosis alone, retracted articles, abstracts, expert opinion articles, and conference presentations were excluded. <b>Results</b> A total of 32 articles were included in the review reporting 156 cases of long-segment tracheal replacement including synthetic (alive at 1-8 years <i>n</i> = 6/64), regenerative medicine (dead at 15 days-55 months <i>n</i> = 4, not reported <i>n</i> = 6), cadaveric tracheal allograft (alive at 5 months-10 years <i>n</i> = 32/38), aortic allograft (alive at 6-85 months <i>n</i> = 12/16), free tissue transfer (alive at 6-108 months <i>n</i> = 13/21), allotransplantation (alive at 6-24 months <i>n</i> = 5/8), and vascular composite allograft (VCA) (alive at 20 months <i>n</i> = 1/1). <b>Conclusion</b> Silicone and Marlex prostheses have poor long-term outcomes. The cadaveric tracheal allograft can only replace near-circumferential tracheal defects and is therefore limited to benign tracheal pathology. Inadequate structural support plagues the aortic allograft and often requires numerous invasive procedures and maintenance of an intraluminal stent. A lack of mucociliary clearance exists in all methods of tracheal replacement except cadaveric tracheal allograft and VCA and can cause fatal mucous plugging and chronic pulmonary infections. VCA and allotransplantation require long-term immunomodulation therapy.</p>","PeriodicalId":44614,"journal":{"name":"Surgery Journal","volume":"10 4","pages":"e43-e52"},"PeriodicalIF":0.8,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Pediatric obesity is a common comorbid condition that may complicate pediatric surgeries, such as appendectomy. Prior research on the consequences of obesity on pediatric appendectomy outcomes have been limited by small-sample sizes and pooled analyses that do not distinguish the effects of surgical approach. Associations between surgical approach, pediatric obesity, and postoperative appendectomy outcomes thus remain unclear. Objective To analyze postoperative appendectomy outcomes by accounting for pediatric obesity, appendectomy approach, and their interaction. This is a retrospective cohort population analysis. Nationwide data of pediatric inpatients from the United States were obtained. All pediatric patients who had an appendectomy were selected from the 2019 Kids' Inpatient Database. Materials and Methods Outcomes variables were the length of stay and postoperative complication rate. The primary exposure variables were pediatric obesity, surgical approach (laparoscopic [LA] vs. open appendectomy [OA]), and an interaction term between the two. Control variables were patient demographics, clinical complexity, and geographic location. Multiple regression was used to determine relationships between the outcome, exposure, and control variables. Results A total of 49,037 pediatric patients had an appendectomy, with the number of OA and LA being 4,517 and 44,420, respectively. LA patients had 5.8% ( p < 0.001) shorter length of stay than OA patients. For obese patients, length of stay was 31.8% ( p < 0.001) longer than for nonobese patients, but LA (compared with OA) reduced it by 19% ( p < 0.007). Obesity had no effect on the number of postoperative complications. Conclusion Obese patients had significantly longer length of stay than nonobese counterparts following OA (31.8%), but this difference was minimized for LA patients (15.81%). There was no association between complication rate, obesity, and surgical approach. Our findings will enable more accurate estimations of pediatric patients' postoperative courses and efficient allocation of limited hospital resources. Further research may wish to study the effects of other common pediatric comorbidities on other procedures.
{"title":"Pediatric Obesity's Effect on Open and Laparoscopic Appendectomy Outcomes.","authors":"Anshul Bhatnagar, Nishtha Nigam, Rohan Anne, Sadashiv Santosh","doi":"10.1055/s-0044-1791968","DOIUrl":"10.1055/s-0044-1791968","url":null,"abstract":"<p><p><b>Background</b> Pediatric obesity is a common comorbid condition that may complicate pediatric surgeries, such as appendectomy. Prior research on the consequences of obesity on pediatric appendectomy outcomes have been limited by small-sample sizes and pooled analyses that do not distinguish the effects of surgical approach. Associations between surgical approach, pediatric obesity, and postoperative appendectomy outcomes thus remain unclear. <b>Objective</b> To analyze postoperative appendectomy outcomes by accounting for pediatric obesity, appendectomy approach, and their interaction. This is a retrospective cohort population analysis. Nationwide data of pediatric inpatients from the United States were obtained. All pediatric patients who had an appendectomy were selected from the 2019 Kids' Inpatient Database. <b>Materials and Methods</b> Outcomes variables were the length of stay and postoperative complication rate. The primary exposure variables were pediatric obesity, surgical approach (laparoscopic [LA] vs. open appendectomy [OA]), and an interaction term between the two. Control variables were patient demographics, clinical complexity, and geographic location. Multiple regression was used to determine relationships between the outcome, exposure, and control variables. <b>Results</b> A total of 49,037 pediatric patients had an appendectomy, with the number of OA and LA being 4,517 and 44,420, respectively. LA patients had 5.8% ( <i>p</i> < 0.001) shorter length of stay than OA patients. For obese patients, length of stay was 31.8% ( <i>p</i> < 0.001) longer than for nonobese patients, but LA (compared with OA) reduced it by 19% ( <i>p</i> < 0.007). Obesity had no effect on the number of postoperative complications. <b>Conclusion</b> Obese patients had significantly longer length of stay than nonobese counterparts following OA (31.8%), but this difference was minimized for LA patients (15.81%). There was no association between complication rate, obesity, and surgical approach. Our findings will enable more accurate estimations of pediatric patients' postoperative courses and efficient allocation of limited hospital resources. Further research may wish to study the effects of other common pediatric comorbidities on other procedures.</p>","PeriodicalId":44614,"journal":{"name":"Surgery Journal","volume":"10 4","pages":"e37-e42"},"PeriodicalIF":0.8,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11502119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-14eCollection Date: 2024-07-01DOI: 10.1055/s-0044-1789192
Dale Dangleben
{"title":"Editorial: Unifying the Global Surgical Community.","authors":"Dale Dangleben","doi":"10.1055/s-0044-1789192","DOIUrl":"https://doi.org/10.1055/s-0044-1789192","url":null,"abstract":"","PeriodicalId":44614,"journal":{"name":"Surgery Journal","volume":"10 3","pages":"e36"},"PeriodicalIF":0.8,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11324348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141983496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-04eCollection Date: 2024-07-01DOI: 10.1055/s-0044-1788065
Abdulmenem Abualsel, Raja Nadeem, Fatema Abdulkarim Al-Ahmed, Ebrahim Adel Almahmeed, Roshan George Varkey, Sameer Almobarak, Ajaz A Wani
Obesity is an emerging worldwide health care issue. It has a direct and indirect bearing on health-related outcomes. Rates of overweight and obesity have grown manifold in the past few decades globally. Once considered a problem of the affluent societies only, obesity is now dramatically on the rise in low- and middle-income countries also. Single anastomosis gastric bypass (SAGB) is one of the combined bariatric procedures adopted for weight loss in patients failing maximal medical therapy. Internal hernia (IH) after SAGB is a less recognized clinical entity. We hereby report our experience with four such cases under light of current available literature. Bariatric procedures are associated with some short- and long-term limitations. IHs are among one of the dreaded complications associated with some bariatric procedures with rates reaching up to 16% after classic Roux-en-Y gastric bypass. The incidence of IH post-SAGB is comparatively rare and is very less frequently reported. Symptoms of IH post-SAGB are quite nonspecific and depend on the time and extent of herniation. The symptoms can vary from benign intermittent colicky pain to severe intra-abdominal pain presenting as a surgical emergency. Routine physical examination and biochemical investigations are nonspecific and unreliable in evaluating those patients. Computed tomography (CT) with intravenous and oral contrast is the most common imaging modality used for preoperative evaluation of those symptoms. The CT findings can be unremarkable in patients having intermittent symptoms/herniation. Diagnostic laparoscopy is the cornerstone for diagnosis and management of patients having high suspicion of IH.
肥胖症是一个新出现的世界性医疗保健问题。它对与健康有关的结果有着直接和间接的影响。在过去几十年里,全球超重和肥胖率成倍增长。肥胖曾一度被认为只是富裕社会的问题,但现在中低收入国家的肥胖率也在急剧上升。单吻合胃旁路术(SAGB)是一种减肥综合手术,适用于药物治疗无效的患者。单吻合胃旁路术后的内疝(IH)在临床上较少得到认可。根据现有文献,我们在此报告四例此类病例的经验。减肥手术存在一些短期和长期的局限性。IH是一些减肥手术的可怕并发症之一,经典的Roux-en-Y胃旁路术后IH发生率高达16%。SAGB术后IH的发生率相对罕见,而且很少有报道。SAGB 术后 IH 的症状没有特异性,取决于疝出的时间和程度。症状可以是良性的间歇性绞痛,也可以是作为手术急症出现的腹内剧痛。常规体格检查和生化检查在评估这些患者时没有特异性,也不可靠。静脉注射和口服造影剂的计算机断层扫描(CT)是术前评估这些症状最常用的成像方式。间歇性症状/疝气患者的 CT 结果可能并不显著。诊断性腹腔镜检查是诊断和处理高度怀疑 IH 患者的基石。
{"title":"Internal Hernia Post-Single Anastomosis Gastric Bypass: Case Series with Review of Literature.","authors":"Abdulmenem Abualsel, Raja Nadeem, Fatema Abdulkarim Al-Ahmed, Ebrahim Adel Almahmeed, Roshan George Varkey, Sameer Almobarak, Ajaz A Wani","doi":"10.1055/s-0044-1788065","DOIUrl":"10.1055/s-0044-1788065","url":null,"abstract":"<p><p>Obesity is an emerging worldwide health care issue. It has a direct and indirect bearing on health-related outcomes. Rates of overweight and obesity have grown manifold in the past few decades globally. Once considered a problem of the affluent societies only, obesity is now dramatically on the rise in low- and middle-income countries also. Single anastomosis gastric bypass (SAGB) is one of the combined bariatric procedures adopted for weight loss in patients failing maximal medical therapy. Internal hernia (IH) after SAGB is a less recognized clinical entity. We hereby report our experience with four such cases under light of current available literature. Bariatric procedures are associated with some short- and long-term limitations. IHs are among one of the dreaded complications associated with some bariatric procedures with rates reaching up to 16% after classic Roux-en-Y gastric bypass. The incidence of IH post-SAGB is comparatively rare and is very less frequently reported. Symptoms of IH post-SAGB are quite nonspecific and depend on the time and extent of herniation. The symptoms can vary from benign intermittent colicky pain to severe intra-abdominal pain presenting as a surgical emergency. Routine physical examination and biochemical investigations are nonspecific and unreliable in evaluating those patients. Computed tomography (CT) with intravenous and oral contrast is the most common imaging modality used for preoperative evaluation of those symptoms. The CT findings can be unremarkable in patients having intermittent symptoms/herniation. Diagnostic laparoscopy is the cornerstone for diagnosis and management of patients having high suspicion of IH.</p>","PeriodicalId":44614,"journal":{"name":"Surgery Journal","volume":"10 3","pages":"e31-e35"},"PeriodicalIF":0.8,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11223885/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141555662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose Postoperative nausea and vomiting (PONV) is a major problem after surgery. This study aimed to demonstrate the incidence of PONV and the potential associated factors in female patients undergoing laparoscopic gastrointestinal surgery against the background of double prophylactic therapy. Methods Our retrospective study recruited 109 female patients undergoing laparoscopic gastrointestinal surgery with double prophylactic therapy, combining palonosetron with dexamethasone, from October 2020 to March 2021, at the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. Patient characteristics and perioperative management factors were included in univariate and multivariate analyses to identify factors influencing PONV. Results Four patients lacked complete records, and of the 105 patients included in the final analysis, 53 (50.5%) patients developed PONV. Two influencing factors for PONV were identified: a history of chemotherapy (odds ratio [OR] 0.325, 95% confidence interval [CI] 0.123-0.856; p = 0.023) and dosage of hydromorphone ≥ 0.02 mg/kg (OR 2.857, 95% CI 1.247-6.550; p = 0.013). The performance of the multivariate logistic regression was evaluated by analyzing receiver operating characteristic curves, resulting in an area under the curve value of 0.673. Conclusion The incidence of PONV remains high in female patients undergoing laparoscopic gastrointestinal surgery, even with double prophylactic therapy. A dosage of hydromorphone ≥ 0.02 mg/kg may increase risk of PONV, whereas a history of chemotherapy might be a protective factor.
{"title":"Postoperative Nausea and Vomiting in Female Patients Undergoing Laparoscopic Gastrointestinal Surgery with Double Prophylactic Therapy.","authors":"Chunmeng Lin, Jing Li, Qian Wu, Tongfeng Luo, Zhinan Zheng","doi":"10.1055/s-0044-1787305","DOIUrl":"10.1055/s-0044-1787305","url":null,"abstract":"<p><p><b>Purpose</b> Postoperative nausea and vomiting (PONV) is a major problem after surgery. This study aimed to demonstrate the incidence of PONV and the potential associated factors in female patients undergoing laparoscopic gastrointestinal surgery against the background of double prophylactic therapy. <b>Methods</b> Our retrospective study recruited 109 female patients undergoing laparoscopic gastrointestinal surgery with double prophylactic therapy, combining palonosetron with dexamethasone, from October 2020 to March 2021, at the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. Patient characteristics and perioperative management factors were included in univariate and multivariate analyses to identify factors influencing PONV. <b>Results</b> Four patients lacked complete records, and of the 105 patients included in the final analysis, 53 (50.5%) patients developed PONV. Two influencing factors for PONV were identified: a history of chemotherapy (odds ratio [OR] 0.325, 95% confidence interval [CI] 0.123-0.856; <i>p</i> = 0.023) and dosage of hydromorphone ≥ 0.02 mg/kg (OR 2.857, 95% CI 1.247-6.550; <i>p</i> = 0.013). The performance of the multivariate logistic regression was evaluated by analyzing receiver operating characteristic curves, resulting in an area under the curve value of 0.673. <b>Conclusion</b> The incidence of PONV remains high in female patients undergoing laparoscopic gastrointestinal surgery, even with double prophylactic therapy. A dosage of hydromorphone ≥ 0.02 mg/kg may increase risk of PONV, whereas a history of chemotherapy might be a protective factor.</p>","PeriodicalId":44614,"journal":{"name":"Surgery Journal","volume":"10 2","pages":"e25-e30"},"PeriodicalIF":0.9,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11147651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-14eCollection Date: 2024-01-01DOI: 10.1055/s-0044-1782655
Dimitrios Symeonidis, Ismini Paraskeva, Athina A Samara, Labrini Kissa, Alexandros Valaroutsos, Eleana Petsa, Konstantinos Tepetes
Introduction Central pancreatectomy (CP) represents an organ-preserving type of pancreatic resection. The procedure has been associated with improved long-term functional results, but increased postoperative morbidity rates, compared with the more radical resection types. The purpose of the present study was to present the outcomes of three consecutive CPs performed in our department. Materials and Methods Between January 2021 and January 2022, three patients (A, B, and C) were submitted to a CP in our department. Relevant patient data including data of the detailed preoperative assessment, operations notes, and recovery charts were prospectively collected and reviewed for all subjects. A scheduled follow-up, at the outpatient clinic, was conducted to assess the long-term functional results. Results The postoperative course of patient A, a 56-year-old male, was complicated by a grade C postoperative pancreatic fistula that required a reoperation. Patient B, a 66-year-old female, developed a biochemical leak that resolved spontaneously while patient C, a 64-year-old male, had a completely uneventful recovery. The length of hospital stay for the three patients was 24, 12, and 8 days, respectively. Regarding the long-term results, patient B was lost to follow-up while both patient A and C were followed up, as outpatients, 21 and 10 months after the operation. During follow-up, in patient A, we did not record the presence of symptoms consistent with pancreatic exocrine insufficiency, the hemoglobin A1C (HbA1C) levels were 7.1% while no additional medications were needed to be prescribed to maintain the glycemic control following surgery. In patient C, a significant weight loss was recorded (body mass index reduction of 11 kg/m 2 ) without however the presence of malabsorption-specific symptoms. The HbA1C levels were 7.7% and optimal glycemic control was achieved with oral antiglycemic agents alone. Conclusion CP should be regarded as a type of pancreatic resection with certain and very limited oncological indications. An approach of balancing the advantages out of the superior postoperative functional results with the drawbacks of the increased procedure-associated morbidity could highlight the patient group that could potentially experience benefits out of this limited type of resection.
导言 中央胰腺切除术(CP)是一种保留器官的胰腺切除术。与更激进的切除类型相比,该手术的长期功能效果更好,但术后发病率增加。本研究旨在介绍我科连续进行的三例胰腺切除术的结果。材料和方法 2021 年 1 月至 2022 年 1 月期间,我科有三名患者(A、B 和 C)接受了 CP 手术。我们前瞻性地收集并审查了所有受试者的相关患者数据,包括详细的术前评估数据、手术记录和康复病历。在门诊进行了定期随访,以评估长期功能效果。结果 患者 A,56 岁,男性,术后并发 C 级胰瘘,需要再次手术。患者 B 是一名 66 岁的女性,出现了生化渗漏,但已自行消退;患者 C 是一名 64 岁的男性,术后恢复完全顺利。三名患者的住院时间分别为 24 天、12 天和 8 天。关于长期结果,患者 B 失去了随访机会,而患者 A 和 C 分别在术后 21 个月和 10 个月接受了门诊随访。在随访期间,患者 A 没有出现与胰腺外分泌功能不全相符的症状,血红蛋白 A1C(HbA1C)水平为 7.1%,术后无需额外用药来维持血糖控制。患者 C 的体重明显减轻(体重指数降低了 11 公斤/米 2),但没有出现吸收不良的特异性症状。患者的 HbA1C 水平为 7.7%,仅靠口服降糖药就能达到最佳血糖控制效果。结论 CP 应被视为一种胰腺切除术,具有某些非常有限的肿瘤适应症。平衡术后功能效果好的优点和手术相关发病率增加的缺点,可以突出这种有限切除术可能带来益处的患者群体。
{"title":"Central Pancreatectomy: Balancing between the Favorable Functional Results and the Increased Associated Morbidity.","authors":"Dimitrios Symeonidis, Ismini Paraskeva, Athina A Samara, Labrini Kissa, Alexandros Valaroutsos, Eleana Petsa, Konstantinos Tepetes","doi":"10.1055/s-0044-1782655","DOIUrl":"10.1055/s-0044-1782655","url":null,"abstract":"<p><p><b>Introduction</b> Central pancreatectomy (CP) represents an organ-preserving type of pancreatic resection. The procedure has been associated with improved long-term functional results, but increased postoperative morbidity rates, compared with the more radical resection types. The purpose of the present study was to present the outcomes of three consecutive CPs performed in our department. <b>Materials and Methods</b> Between January 2021 and January 2022, three patients (A, B, and C) were submitted to a CP in our department. Relevant patient data including data of the detailed preoperative assessment, operations notes, and recovery charts were prospectively collected and reviewed for all subjects. A scheduled follow-up, at the outpatient clinic, was conducted to assess the long-term functional results. <b>Results</b> The postoperative course of patient A, a 56-year-old male, was complicated by a grade C postoperative pancreatic fistula that required a reoperation. Patient B, a 66-year-old female, developed a biochemical leak that resolved spontaneously while patient C, a 64-year-old male, had a completely uneventful recovery. The length of hospital stay for the three patients was 24, 12, and 8 days, respectively. Regarding the long-term results, patient B was lost to follow-up while both patient A and C were followed up, as outpatients, 21 and 10 months after the operation. During follow-up, in patient A, we did not record the presence of symptoms consistent with pancreatic exocrine insufficiency, the hemoglobin A1C (HbA1C) levels were 7.1% while no additional medications were needed to be prescribed to maintain the glycemic control following surgery. In patient C, a significant weight loss was recorded (body mass index reduction of 11 kg/m <sup>2</sup> ) without however the presence of malabsorption-specific symptoms. The HbA1C levels were 7.7% and optimal glycemic control was achieved with oral antiglycemic agents alone. <b>Conclusion</b> CP should be regarded as a type of pancreatic resection with certain and very limited oncological indications. An approach of balancing the advantages out of the superior postoperative functional results with the drawbacks of the increased procedure-associated morbidity could highlight the patient group that could potentially experience benefits out of this limited type of resection.</p>","PeriodicalId":44614,"journal":{"name":"Surgery Journal","volume":"10 1","pages":"e20-e24"},"PeriodicalIF":0.9,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10965197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}