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Molecular Imaging and Radionuclide Therapy最新文献

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A Rare Case of Triple Primary Malignant Neoplasms (RCC and Colon Cancer) Detected by 18F-FDG PET/CT 一例通过 18F-FDG PET/CT 检测出的罕见的三原发性恶性肿瘤（RCC 和结肠癌）病例
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Molecular Imaging and Radionuclide Therapy
Pub Date : 2024-07-08 DOI: 10.4274/mirt.galenos.2024.61214
Petya Nikolova, Valeria Hadzhiyska, Yavor Gramatikov, Stefani Veneva, Georgi Gaydarov, Elena Raycheva, M. Ilcheva
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引用次数: 0
A Comprehensive Analysis of Volumetric 68Ga-PSMA PET/CT Parameters, Clinical and Histopathologic Features: Evaluation of the Predictive Role. 全面分析容积 68Ga-PSMA PET/CT 参数、临床和组织病理学特征：评估预测作用。
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Molecular Imaging and Radionuclide Therapy
Pub Date : 2024-06-28 DOI: 10.4274/mirt.galenos.2024.56933
Gözde Mutevelizade, Yasemin Parlak, Ceren Sezgin Arıkbası, Gül Gümüşer, Elvan Sayit

Objectives: To evaluate the relationships between volumetric 68Ga-prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) parameters, Gleason score (GS), prostate-specific antigen (PSA) levels, histopathological data, and metastatic status in newly diagnosed prostate cancer (PCa) patients and to assess the predictive factors for progression despite treatment.

Methods: A total of 78 newly diagnosed patients with PCa who had 68Ga-PSMA PET/CT scans were included. Clinical parameters, histopathological data, and metastatic status were documented, and volumetric parameters of primary prostate lesions were measured. All obtained data were compared statistically.

Results: Primary prostate tumor maximum standardized uptake value (SUVmax) and GS were significantly related to serum PSA levels (p<0.05). PSA levels and SUVmax values were significantly higher in patients with lymph node metastases than in those without. GS was found to be significantly increased in metastatic patients. PSMA-derived tumor volume (PSMA-TV) and total lesion PSMA of the primary lesion had a significant relationship with PSA value, GS, and regional lymph node metastases. Receiver operating characteristic analysis, conducted in patients with metastatic and localized disease, identified the cutoff value for SUVmax as 10.85. According to the results of the logistic regression analysis, PSMA-TV was found to be a predictive factor for progression despite treatment.

Conclusion: 68Ga-PSMA PET/CT remains an invaluable imaging modality that should be considered first in PCa staging because of its superior compatibility with clinical and histopathologic data. The importance of this method goes beyond diagnostic accuracy; it also extends into the predictive domain, where the PSMA-TV value of primary prostate lesions is a potential predictor of treatment efficacy. This information is valuable for personalizing patient treatment, improving prognostic accuracy, and predicting clinical outcomes.

研究目的评估新诊断的前列腺癌（PCa）患者的容积68Ga-前列腺特异性膜抗原（PSMA）正电子发射断层扫描/计算机断层扫描（PET/CT）参数、格里森评分（GS）、前列腺特异性抗原（PSA）水平、组织病理学数据和转移状态之间的关系，并评估治疗后病情进展的预测因素：方法：共纳入 78 名接受过 68Ga-PSMA PET/CT 扫描的新诊断 PCa 患者。记录临床参数、组织病理学数据和转移状态，并测量原发性前列腺病变的体积参数。对所有获得的数据进行统计学比较：结果：原发性前列腺肿瘤的最大标准化摄取值（SUVmax）和GS与血清PSA水平有显著关系（有淋巴结转移的患者的pmax值明显高于无淋巴结转移的患者）。淋巴结转移患者的 GS 值明显升高。原发病灶的 PSMA 衍生肿瘤体积（PSMA-TV）和总病灶 PSMA 与 PSA 值、GS 和区域淋巴结转移有显著关系。对转移性和局部性疾病患者进行的接收器操作特征分析确定了 SUVmax 的临界值为 10.85。结论：68Ga-PSMA PET/CT 仍是一种宝贵的成像模式，由于其与临床和组织病理学数据的兼容性极佳，因此在 PCa 分期中应首先考虑使用这种模式。该方法的重要性不仅体现在诊断准确性上，还体现在预测性上，原发性前列腺病变的 PSMA-TV 值是治疗效果的潜在预测指标。这些信息对于患者的个性化治疗、提高预后准确性和预测临床结果都很有价值。
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引用次数: 0
Paget’s Disease Mimicking Prostate Cancer Metastasis with 68Ga-PSMA PET/CT 利用 68Ga-PSMA PET/CT 模拟前列腺癌转移的髓鞘病
IF 0.9 Q3 Medicine
Molecular Imaging and Radionuclide Therapy
Pub Date : 2024-06-13 DOI: 10.4274/mirt.galenos.2024.03521
Melis Oflas, E. Isik, Z. Özkan, Duygu Has Şimşek, Y. Şanlı
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引用次数: 0
Bone Marrow Necrosis with Underlying Skeletal Lymphoma Evaluated by 18F-FDG PET/CT and MRI 通过 18F-FDG PET/CT 和核磁共振成像评估骨髓坏死伴骨骼淋巴瘤的情况
IF 0.9 Q3 Medicine
Molecular Imaging and Radionuclide Therapy
Pub Date : 2024-06-13 DOI: 10.4274/mirt.galenos.2024.70037
Le Song, Hui Li, Weifang Zhang
{"title":"Bone Marrow Necrosis with Underlying Skeletal Lymphoma Evaluated by 18F-FDG PET/CT and MRI","authors":"Le Song, Hui Li, Weifang Zhang","doi":"10.4274/mirt.galenos.2024.70037","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2024.70037","url":null,"abstract":"","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"48 10","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141349071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tc-99m-MDP Uptake in Extraosseous Metastases From Ovarian Papillary Serous Adenocarcinoma 卵巢乳头状浆液性腺癌骨外转移的 Tc-99m-MDP 摄取
IF 0.9 Q3 Medicine
Molecular Imaging and Radionuclide Therapy
Pub Date : 2024-06-13 DOI: 10.4274/mirt.galenos.2024.72687
Komal Bishnoi, K. Agrawal, P. Patro, G. Parida
{"title":"Tc-99m-MDP Uptake in Extraosseous Metastases From Ovarian Papillary Serous Adenocarcinoma","authors":"Komal Bishnoi, K. Agrawal, P. Patro, G. Parida","doi":"10.4274/mirt.galenos.2024.72687","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2024.72687","url":null,"abstract":"","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"94 3","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141347720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distinguishing Bronchial Carcinoid from Benign Bronchocele using 68Ga-DOTATOC PET/CT Imaging 利用 68Ga-DOTATOC PET/CT 成像技术区分支气管类癌和良性支气管瘤
IF 0.9 Q3 Medicine
Molecular Imaging and Radionuclide Therapy
Pub Date : 2024-06-13 DOI: 10.4274/mirt.galenos.2024.50103
Akram Al-Ibraheem, Raghad Alhouwari, Baraa Alsyouf, A. Abdlkadir, Hussam Haddad
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引用次数: 0
Multiple Bone Involvement in Low-grade Myofibroblastic Sarcoma Demonstrated on 18F-FDG PET/CT 18F-FDG PET/CT 显示低级别肌纤维母细胞肉瘤多处骨质受累
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Molecular Imaging and Radionuclide Therapy
Pub Date : 2024-06-13 DOI: 10.4274/mirt.galenos.2024.14238
Hui Li, Xiaoyan Hou, Na Guo, Le Song, Weifang Zhang
{"title":"Multiple Bone Involvement in Low-grade Myofibroblastic Sarcoma Demonstrated on 18F-FDG PET/CT","authors":"Hui Li, Xiaoyan Hou, Na Guo, Le Song, Weifang Zhang","doi":"10.4274/mirt.galenos.2024.14238","DOIUrl":"https://doi.org/10.4274/mirt.galenos.2024.14238","url":null,"abstract":"","PeriodicalId":44681,"journal":{"name":"Molecular Imaging and Radionuclide Therapy","volume":"4 9","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141349638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intrathyroidal Parathyroid Adenoma 甲状旁腺内腺瘤
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Molecular Imaging and Radionuclide Therapy
Pub Date : 2024-06-13 DOI: 10.4274/mirt.galenos.2024.66934
Sara Zouggari, Mohamed Aziz Bsiss, A. Matrane, Abdelouahed Marrat, Ibtissam Zrara Touiti
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引用次数: 0
A Case of Diffuse Infiltrative Hepatocellular Carcinoma with Marked Response to Sorafenib Treatment Evidenced by 18F-FDG PET/MRI 一例通过 18F-FDG PET/MRI 证实对索拉非尼治疗有明显反应的弥漫浸润性肝细胞癌病例
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Molecular Imaging and Radionuclide Therapy
Pub Date : 2024-04-16 DOI: 10.4274/mirt.galenos.2024.36043
E. Özkan, Burak Demir, Diğdem Kuru Öz, Y. Ürün, N. O. Küçük
A 73-year-old woman with known diagnosis of chronic hepatitis B infection referred for 18 F-fluorodeoxyglucose positron emission tomography/ computed tomography ( 18 F-FDG PET/CT) and magnetic resonance imaging (MRI) after detection of a liver mass with 9 cm diameter in contrast enhanced CT. However, 18 F-FDG PET/CT and MRI revealed diffuse infiltrating hepatocellular carcinoma lesions other than previously defined mass. After 9 months of Sorafenib treatment serum alpha feto protein levels dropped from 60,500 ng/mL to 801 ng/mL. Later 18 F-FDG PET/MRI was performed for evaluation of response to treatment and revealed marked response to treatment
一名 73 岁的妇女已知诊断为慢性乙型肝炎感染，在对比增强 CT 中发现一个直径 9 厘米的肝脏肿块，随后转诊到医院进行 18 F-FDG 正电子发射/计算机断层扫描（18 F-FDG PET/CT）和磁共振成像（MRI）检查。然而，18 F-FDG PET/CT 和核磁共振成像显示，除了之前确定的肿块外，还有弥漫浸润性肝细胞癌病灶。索拉非尼治疗9个月后，血清甲胎蛋白水平从60,500纳克/毫升降至801纳克/毫升。随后进行了 18 F-FDG PET/MRI，以评估治疗反应，结果显示治疗反应明显
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引用次数: 0
Diagnostic Performance of FAPI PET/CT vs. 18F-FDG PET/CT in Evaluation of Liver Tumors: A Systematic Review and Meta-analysis FAPI PET/CT 与 18F-FDG PET/CT 在肝脏肿瘤评估中的诊断性能：系统回顾与元分析
IF 0.9 Q3 Medicine
Molecular Imaging and Radionuclide Therapy
Pub Date : 2024-04-16 DOI: 10.4274/mirt.galenos.2024.99705
Parneet Singh, T. Singhal, G. Parida, Ashique Rahman, K. Agrawal
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引用次数: 0
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