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Early detection and risk factors of congenital hip dislocation in Morocco. 摩洛哥先天性髋关节脱位的早期发现和风险因素。
IF 0.8 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 eCollection Date: 2023-11-30 DOI: 10.4081/jphia.2023.2589
Adri Ilham, Touloun Oulaid, Boussaa Samia

Congenital dislocation of the hip is a malformation of the lower limbs that could be complicated by a disabling physical handicap with long-term psychological and social repercussions if detected late. This study aims to describe the screening for congenital hip dislocation and to investigate the association between the occurrence of this anomaly and possible risk factors in Morocco. The study was based on the exploitation of the records of children treated at the trauma and orthopedics department of the Mohammed VI University Hospital in Marrakech, Morocco. It concerned 160 cases with a 5-year follow-up from January 2016 to March 2021. The results of the study showed that 56.7% of the affected children had a bilateral dislocation and 25.8% of the cases had a left-sided dislocation. The malformation occurred more frequently in females 69.2%. A familial disposition to the malformation was found in about 22% of the cases. The diagnosis was late (at walking age) in 61% of children following the onset of lameness with or without pain in 91% of children. In 41.87% of the hips, the reduction was surgical, with 28% failure dominated by acetabular dysplasia in 11%. The risk factors for congenital hip dislocation identified in our setting were dominated by sex, primiparity, consanguineous marriage, and the presence of a family history of dislocation. Communication of risk factors specific to our setting to healthcare personnel will allow them to guide the diagnosis and increase vigilance in the at-risk population for management that prevents the development of complications.

先天性髋关节脱位是一种下肢畸形,如果发现较晚,可能会并发致残性肢体残疾,并造成长期的心理和社会影响。本研究旨在描述摩洛哥先天性髋关节脱位的筛查情况,并调查这种畸形的发生与可能的风险因素之间的关联。这项研究基于对在摩洛哥马拉喀什穆罕默德六世大学医院创伤和矫形科接受治疗的儿童病历的利用。研究涉及 160 个病例,自 2016 年 1 月至 2021 年 3 月进行了为期 5 年的随访。研究结果显示,56.7%的患儿为双侧脱位,25.8%的病例为左侧脱位。畸形多发于女性,占69.2%。约22%的病例有家族遗传倾向。61%的患儿诊断较晚(在行走年龄),91%的患儿在出现伴有或不伴有疼痛的跛行后才确诊。41.87%的髋关节通过手术切除,28%的手术失败,其中11%为髋臼发育不良。在我们的病例中,先天性髋关节脱位的风险因素主要是性别、初产妇、近亲结婚以及有脱位家族史。向医护人员传达我们的环境所特有的风险因素将使他们能够指导诊断,并提高高危人群的警惕性,以预防并发症的发生。
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引用次数: 0
Impact of Covid-19 Pandemic on the Utilization and Delivery of Healthcare Services among Outpatients during the Early Phase of the Pandemic in Nigeria. 尼日利亚 Covid-19 大流行初期对门诊病人利用和提供医疗服务的影响。
IF 0.8 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 eCollection Date: 2023-11-30 DOI: 10.4081/jphia.2023.2317
Daniel Ehis Aigbonoga, Joshua Temidayo Obarombi, Williams Yobuh Shekinah, Tijani Shehu Adiat, Taye David Owoputi, Adebimpe Rukayat Jubril, Azeezat Morolake Salawudeen, Abiodun Opeyemi Lawal, Abiodun David Akintayo, Faith Anuoluwapo Oluwadamilare, Similoluwa Olamide Oluwalana, Dayo Sodiq Adesokan, Richard Ayobami Oguntoye

During the early phase of the COVID-19 pandemic, some infection control measures were implemented to keep people safe and control the spread of the virus. These measures however were observed to cause significant delay or interruption in the delivery and utilization of healthcare services. The purpose of this study was to determine the impact of the COVID-19 pandemic on the utilization and delivery of healthcare services by outpatients in Nigeria during the early phase of the pandemic. A retrospective cross-sectional study design was utilized. We sampled 373 outpatients who had received healthcare services before and during the pandemic in the University College Hospital, Ibadan using convenience sampling. Descriptive and inferential statistics (t-test) were carried out and the level of significance was set as P<0.05. Healthcare utilization was significantly impacted by the pandemic as there was a reduction in hospital visits by patients during the pandemic (P<0.0003). Restriction of movement and fear of contracting the virus was identified as reasons for the reduction in healthcare services utilization in about 59% of the participants. Patients rated the quality healthcare services delivered to them as 'average' during the pandemic as opposed to 'good' before the pandemic. The findings of this study showed that the COVID-19 pandemic had a significant impact on patients' utilization of healthcare services as well as the delivery of adequate healthcare services in the hospital during the early phases of the pandemic. Therefore, we recommend that efforts be made to improve hospitals and nationwide preparedness for future pandemics to prevent healthcare interference and delay.

在 COVID-19 大流行的早期阶段,为了保证人们的安全和控制病毒的传播,采取了一些感染控制措施。但据观察,这些措施对医疗保健服务的提供和使用造成了严重的延误或中断。本研究旨在确定 COVID-19 大流行对尼日利亚门诊病人在大流行初期使用和提供医疗服务的影响。研究采用了回顾性横断面研究设计。我们采用便利抽样法在伊巴丹大学学院医院抽取了 373 名在大流行之前和期间接受过医疗服务的门诊患者。我们进行了描述性和推断性统计(t 检验),显著性水平设定为 P
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引用次数: 0
African Global Health: An initiative committed to achieving Health Sovereignty in the Global South. 非洲全球卫生:致力于在全球南部实现健康主权的倡议。
IF 0.8 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 eCollection Date: 2023-10-31 DOI: 10.4081/jphia.2024.2867
Morgan Chetty, Enrique Teran, Luwaga Patrick, Rania Mamdouh, Sunitha Chandrasekhhar Srinivas, Jean Kaseya, Nicaise Ndembi, Sara Touirsi, Imane Kendili
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引用次数: 0
Depot-medroxyprogesterone acetate: Lipid profile changes and associated cardiovascular risks among acceptors in Sagamu, South West Nigeria. 醋酸去甲羟孕酮:尼日利亚西南部萨加穆接受者的血脂变化和相关心血管风险。
IF 0.8 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 eCollection Date: 2023-11-30 DOI: 10.4081/jphia.2023.1664
Oluwaseyi Odelola, Adebayo Akadri

Depot-medroxyprogesterone acetate (DMPA) is a highly effective long acting reversible contraceptive. Alterations in lipid profile have been associated with use of DMPA, however there is considerable debate about how profound these effects are. Hence the aim of this study is to determine the effect of DMPA on lipid profile and the associated cardiovascular risks. This was a prospective longitudinal study conducted at the family planning clinic of Olabisi Onabanjo University Teaching Hospital Sagamu, Ogun State. Sixty eight new acceptors of DMPA who had their blood samples collected for lipid profile assays at initiation of DMPA, and then at 3 months and 6 months. Data were analyzed using SPSS version 24. After 3 months of DMPA use, there was statistically significant increase in serum Total Cholesterol (TC) concentration (P=0.022), serum Low Density Lipoprotein (LDL) concentration (P=0.033), non significant increase in serum Triglyceride (TG) concentration (P=0.150) and non-significant decrease in serum Higher Density Lipoprotein (HDL) concentration (P=0.076). However, after 6 months of DMPA use, there was statistically significant increase in serum TC concentration (P=0.002), serum LDL concentration (P=0.003), serum TG concentration (P=0.001) and significant decrease in serum HDL concentration (P=0.001). DMPA use is associated with increased serum TC, TG, LDL, and reduction in HDL after 6 months of use. These changes in lipid profile may increase the risk of cardiovascular diseases.

醋酸去羟孕酮(DMPA)是一种高效的长效可逆避孕药。血脂状况的改变与使用 DMPA 有关,但对于这些影响的深远程度还存在相当大的争议。因此,本研究旨在确定 DMPA 对血脂状况的影响以及相关的心血管风险。这是一项前瞻性纵向研究,在奥贡州奥拉比西-奥纳班霍大学萨加穆教学医院的计划生育诊所进行。68 名新接受 DMPA 的患者在开始使用 DMPA 时、3 个月后和 6 个月后被采集血样进行血脂分析。数据使用 SPSS 24 版进行分析。使用 DMPA 3 个月后,血清总胆固醇(TC)浓度(P=0.022)、血清低密度脂蛋白(LDL)浓度(P=0.033)有统计学意义的显著上升,血清甘油三酯(TG)浓度(P=0.150)无显著上升,血清高密度脂蛋白(HDL)浓度(P=0.076)无显著下降。然而,使用 DMPA 6 个月后,血清 TC 浓度(P=0.002)、血清 LDL 浓度(P=0.003)、血清 TG 浓度(P=0.001)均有统计学意义的显著增加,而血清 HDL 浓度则显著下降(P=0.001)。使用 DMPA 6 个月后,血清 TC、TG、LDL 增高,HDL 降低。这些血脂变化可能会增加罹患心血管疾病的风险。
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引用次数: 0
Missed opportunity for tuberculosis screening among patients presenting at two health facilities in Manafwa district, Uganda. 在乌干达马纳夫瓦区两家医疗机构就诊的患者错失结核病筛查机会。
IF 0.8 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 eCollection Date: 2023-11-30 DOI: 10.4081/jphia.2023.2682
Titus Wamulima, John Peter Masette Masaba, David Musoke, David Mukunya, Joseph Kb Matovu

Missed opportunities for Tuberculosis (TB) screening are key drivers of continued tuberculosis transmission. To determine the proportion of and factors associated with missing TB screening amongst patients who attended Bubulo and Butiru health facilities in the Manafwa district to inform future TB prevention and control efforts in Uganda. This was a facility-based, cross-sectional study with quantitative methods of data collection. 125 patients (≥18 years) with at least one symptom suggestive of TB were systematically selected and interviewed at the exit. Data analysis was done by Stata version 15, using a cluster-based logistic regression model. Of the 125 patients enrolled at both sites, 39% (n=49) were aged between 30 and 49 years; 75.2% (n=94) were females; 44% (n=55) were married while 66.4% (n=83) had a primary level of education. Of the patients enrolled in the study, 68% (n=85) had a missed opportunity for TB screening. Having a; post-primary education level (Adjusted Odds Ratio [AOR]=5.9; 95% Confidence Interval [95% CI]=1.3, 27.1) and attending Bubulo HCIV (AOR=0.01; 95% CI: 0.01, 0.2) were significantly associated with having a missed opportunity for TB screening. Our findings show that slightly more than two-thirds of the patients who presented to the study health facilities with symptoms suggestive of TB missed the opportunity to be screened for TB. Study findings suggest a need for interventions to increase TB screening, particularly among better-educated TB patients.

错过结核病(TB)筛查机会是导致结核病持续传播的关键因素。目的是确定在马纳夫瓦区布布洛和布蒂鲁医疗机构就诊的患者中错过结核病筛查的比例及相关因素,为乌干达未来的结核病防控工作提供参考。这是一项基于医疗机构的横断面研究,采用定量方法收集数据。系统地挑选了 125 名至少有一种症状提示为肺结核的患者(≥18 岁),并在出口处对他们进行了访谈。数据分析采用基于聚类的逻辑回归模型,由 Stata 15 版本完成。在两个地点登记的 125 名患者中,39%(49 人)的年龄在 30 至 49 岁之间;75.2%(94 人)为女性;44%(55 人)已婚,66.4%(83 人)受过初等教育。在参与研究的患者中,68%(n=85)错过了结核病筛查的机会。小学后教育程度(调整后患病率比 [AOR]=5.9;95% 置信区间 [95% CI]=1.3, 27.1)和参加 Bubulo HCIV(AOR=0.01;95% CI:0.01, 0.2)与错过结核病筛查机会显著相关。我们的研究结果表明,略高于三分之二的患者在出现肺结核症状后前往研究的医疗机构就诊时错过了肺结核筛查的机会。研究结果表明,有必要采取干预措施来提高结核病筛查率,尤其是在受教育程度较高的结核病患者中。
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引用次数: 0
Perception and experience of relatives of pregnant teenagers: A qualitative study in the North and Northeast departments of Haiti. 怀孕少女亲属的看法和经历:海地北部和东北部省份的定性研究。
IF 0.8 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-01 eCollection Date: 2023-11-30 DOI: 10.4081/jphia.2023.2436
Léonel Philibert, Patrice Ngangue, Judith Lapierre, Paulin Mulatris, Alice Prophète, Gbètogo Maxime Kiki, Gisèle Mandiangu Ntanda

Teenage pregnancy remains a global problem because of its consequences for the teenager, her child, her family, and society. In Haiti, this type of pregnancy burdens the family economy. In addition, the adolescent fertility rate is still high, despite efforts to reduce it. This article aims to analyze the perception and experiential experience of relatives of pregnant adolescents in Haiti. A qualitative study design based on Dewey's social survey was conducted. Data were collected from 17 relatives (partners, parents, guardians, and others) of pregnant adolescents in Haiti's North and Northeast departments. These data were analyzed using thematic analysis. According to the results, teenage pregnancy is seen as a disaster or a social problem in Haiti. It leads to many psychosocial and economic difficulties for the relatives, who are the only source of economic and social support for pregnant adolescents. Considering the vulnerability of relatives, policies, and interventions aimed at reducing the negative consequences of teenage pregnancy should consider this group of individuals.

少女怀孕仍然是一个全球性问题,因为它对少女、其子女、家庭和社会都有影响。在海地,这种怀孕给家庭经济造成了负担。此外,尽管努力降低少女生育率,但生育率仍然很高。本文旨在分析海地怀孕少女亲属的看法和经验。研究采用了基于杜威社会调查的定性研究设计。研究人员从海地北部省和东北部省怀孕少女的 17 名亲属(伴侣、父母、监护人等)处收集了数据。对这些数据进行了专题分析。结果显示,少女怀孕在海地被视为一种灾难或社会问题。少女怀孕会给亲属带来许多社会心理和经济困难,而亲属是怀孕少女经济和社会支持的唯一来源。考虑到亲属的脆弱性,旨在减少少女怀孕负面影响的政策和干预措施应考虑到这一群体。
{"title":"Perception and experience of relatives of pregnant teenagers: A qualitative study in the North and Northeast departments of Haiti.","authors":"Léonel Philibert, Patrice Ngangue, Judith Lapierre, Paulin Mulatris, Alice Prophète, Gbètogo Maxime Kiki, Gisèle Mandiangu Ntanda","doi":"10.4081/jphia.2023.2436","DOIUrl":"10.4081/jphia.2023.2436","url":null,"abstract":"<p><p>Teenage pregnancy remains a global problem because of its consequences for the teenager, her child, her family, and society. In Haiti, this type of pregnancy burdens the family economy. In addition, the adolescent fertility rate is still high, despite efforts to reduce it. This article aims to analyze the perception and experiential experience of relatives of pregnant adolescents in Haiti. A qualitative study design based on Dewey's social survey was conducted. Data were collected from 17 relatives (partners, parents, guardians, and others) of pregnant adolescents in Haiti's North and Northeast departments. These data were analyzed using thematic analysis. According to the results, teenage pregnancy is seen as a disaster or a social problem in Haiti. It leads to many psychosocial and economic difficulties for the relatives, who are the only source of economic and social support for pregnant adolescents. Considering the vulnerability of relatives, policies, and interventions aimed at reducing the negative consequences of teenage pregnancy should consider this group of individuals.</p>","PeriodicalId":44723,"journal":{"name":"Journal of Public Health in Africa","volume":"14 11","pages":"2436"},"PeriodicalIF":0.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10946304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monitoring progress on antimicrobial resistance response in the WHO African Region: Insights from the Tracking AMR Country Self-Assessment Survey (TrACSS) 2021. Results for the Human Health Sector 监测世卫组织非洲地区抗菌药物耐药性应对工作的进展情况:2021 年跟踪 AMR 国家自我评估调查 (TrACSS) 的启示。人类健康部门的结果
IF 0.8 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-01-02 DOI: 10.4081/jphia.2023.2392
L. Gahimbare, Ambele Judith Mwamelo, Yahaya Ali Ahmed, Walter Fuller, Ponnu Payidara, Pravarsha Prakash, Anand Balachandran, E. L. Makubalo
Background: Antimicrobial resistance (AMR) is a major 21st century global health challenge. The WHO African Region Member States committed to develop and implement multisectoral national action plans (NAPs) that address AMR, in line with the Global Action Plan on AMR (GAP).Objective: The aim of this paper is to present the progress of AMR response in the WHO African Region based on the annual Tracking AMR Country Self-Assessment Survey (TrACSS), with a focus on human health indicators.Methods: This was a secondary data analysis of responses from forty-one countries that participated in the 2021 TrACSS.Results: Of the 41 countries that responded to the 2021 TrACSS, 35(85%) have developed NAPs. Fifteen 15(37%) of countries have functional AMR multisector working groups. 55% (21/41) of countries are collating data nationally on AMR surveillance. Forty nine percent of countries conducted small-scale AMR awareness campaigns and 53% (21/41) covered AMR in some pre- and in-service training for human health workers. While 83% of countries reported having laws and regulations on the prescription and sale of antimicrobials, only 32% (13/41) have national systems for monitoring antimicrobial use. Twenty-three (58%, 23/41) reported having Infection Prevention and Control (IPC) programs at select health facilities. Conclusion: Countries have developed and are implementing AMR NAPs. Gaps still exist across key indicators monitored through TrACSS. Effective AMR response requires established functional multisectoral governance mechanisms in the One Health approach; political commitment, sustainable funding, and clear monitoring and reporting is critical. 
背景:抗菌素耐药性(AMR)是 21 世纪全球卫生面临的一项重大挑战。世卫组织非洲地区成员国承诺根据《全球抗菌药物耐药性行动计划》(GAP)制定并实施应对抗菌药物耐药性的多部门国家行动计划(NAP):本文旨在根据年度跟踪 AMR 国家自我评估调查 (TrACSS),介绍世卫组织非洲地区应对 AMR 的进展情况,重点关注人类健康指标:这是对参加2021年TrACSS的41个国家的答复进行的二次数据分析:在参与 2021 年 TrACSS 调查的 41 个国家中,有 35 个国家(85%)制定了国家行动方案。15个国家(37%)设立了功能性 AMR 多部门工作组。55%的国家(21/41)正在整理本国的 AMR 监测数据。49% 的国家开展了小规模的 AMR 宣传活动,53% 的国家(21/41)在对卫生工作者的一些岗前和在职培训中涉及 AMR。虽然 83% 的国家报告已制定了有关抗菌药物处方和销售的法律法规,但只有 32% 的国家(13/41)建立了监测抗菌药物使用情况的国家系统。23个国家(58%,23/41)报告在选定的医疗机构中实施了感染预防与控制(IPC)计划。结论:各国已制定并正在实施 AMR 国家行动计划。通过 TrACSS 监测的主要指标之间仍存在差距。有效的 AMR 应对措施需要在 "一个健康 "方法中建立功能性多部门治理机制;政治承诺、可持续供资以及明确的监测和报告至关重要。
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引用次数: 0
Determinants of fatigue while driving among two-wheeled vehicle drivers: Exploratory approach from secondary analysis based on hospital data, Benin 两轮车驾驶员疲劳驾驶的决定因素:基于医院数据的二次分析探索方法,贝宁
IF 0.8 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-01-02 DOI: 10.4081/jphia.2023.2601
Yolaine Glèlè Ahanhanzo, Alphonse Kpozehouen, Lamidhi Salami, Nicolas Gaffan, Bella Hounkpè Dos Santos, Alain Levêque
Background: Fatigue while driving is one of the risk factors of road crashes. It’s still poorly considered in interventions because of insufficient literature. In addition, the literature on this issue doesn’t focus on two-wheelers, the most frequent users in the Benin context. Objective: The study examined the prevalence of fatigue while driving among two-wheeled vehicle drivers and the related factors. Methods: It’s a secondary baseline data analysis from a cohort of road crash victims recruited from five hospitals in the country. Patients who identified themselves as drivers during the accident were included. Data on individual characteristics, including fatigue status in the moments preceding the collision, and other risk factors and environmental settings, were extracted. We used multivariate logistic regression. Results: Among the respondents, 12.20% (95% CI=10.20-14.53) reported fatigue in the moments preceding the collision. The odds of fatigue while driving were significantly higher in male drivers (aOR = 3.60; 95% CI=1.08-11.98), during professional trips (aOR = 2.09; 95% CI=1.30-3.37), in non-helmet wearers (aOR = 1.85; 95% CI=1.09-3.13), in users of stimulants (aOR = 3.13; 95% CI=1.50-6.54), in those with a history of chronic diseases (aOR = 1.95; 95% CI=1.16-3.27), at dusk (aOR = 4.22; 95% CI=2.22-8.02), at night (aOR = 6.90; 95% CI=3.95-12.05), and on Inter-State National Roads (aOR = 2.01; 95% CI=1.18-3.43). Conclusion: Fatigue is a risk factor for road crashes in Benin, associated with other risk factors that highlight particularly vulnerable profiles and groups. Integrating prevention policies based on these cumulative risk factors will result in efficiency improvements
背景:疲劳驾驶是道路交通事故的风险因素之一。由于文献资料不足,在干预措施中对这一问题的考虑仍然很少。此外,有关这一问题的文献并不关注两轮车,而在贝宁,两轮车是最常见的使用者。研究目的研究调查了两轮车驾驶员疲劳驾驶的发生率及其相关因素。研究方法这是从该国五家医院招募的道路交通事故受害者群组中进行的二次基线数据分析。研究对象包括在事故中自称为驾驶员的患者。我们提取了有关个人特征的数据,包括碰撞前瞬间的疲劳状态、其他风险因素和环境背景。我们采用了多变量逻辑回归法。结果显示在受访者中,12.20%(95% CI=10.20-14.53)的人表示在碰撞发生前的瞬间感到疲劳。男性驾驶员(aOR=3.60;95% CI=1.08-11.98)、职业旅行期间(aOR=2.09;95% CI=1.30-3.37)、不戴头盔者(aOR=1.85;95% CI=1.09-3.13)、兴奋剂使用者(aOR=3.13;95% CI=1.50-6.54)、有慢性病史者(aOR=1.95;95% CI=1.16-3.27)、黄昏(aOR=4.22;95% CI=2.22-8.02)、夜间(aOR=6.90;95% CI=3.95-12.05)以及在州际国道上(aOR=2.01;95% CI=1.18-3.43)。结论疲劳是贝宁道路交通事故的一个风险因素,与其他风险因素相关联,凸显了特别易受伤害的特征和群体。根据这些累积的风险因素整合预防政策将提高效率
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引用次数: 0
SARS-CoV-2 IgG antibody status in unvaccinated and 2-dose vaccinated Indonesians 未接种疫苗和接种 2 剂疫苗的印度尼西亚人的 SARS-CoV-2 IgG 抗体状况
IF 0.8 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-01-02 DOI: 10.4081/jphia.2023.2697
Laura Yamani, Juniastuti Juniastuti, Ni Luh Ayu Megasari, Takako Utsumi, Nur Sahila, Alifia Salma Pangestika, Serius Miliyani Dwi Putri, Chung-Yi Li, Santi Martini, M. A. Isfandiari, M. Lusida
 Indonesia began deploying a COVID-19 vaccine in January 2021, prioritising vaccination for high-risk groups such as healthcare workers, the elderly and those with comorbidities, and ending with the general public due to limited vaccine availability. Our study aimed to evaluate antibody response in Indonesians who had received two doses of the vaccine versus those who had not. The study design was a cohort study involving 46 unvaccinated people and 23 people who had received the second dose of the AstraZeneca vaccine over three months ago. Methods used for the qualitative and quantitative detection of IgG antibodies included rapid RI-GHA and ELISA tests. Findings showed that positive IgG antibodies qualitatively detected by the rapid RI-GHA test were significantly higher in those vaccinated (60.9%) than in unvaccinated people (26.1%). Using the ELISA assay, all vaccinated individuals qualitatively showed positive antibodies (cut-off ≥4.33 BAU/mL), and the average quantitative titer of anti-SARS-CoV-2 s-RBD IgG was significantly higher in vaccinated (157.06±238.68 BAU/mL) than in unvaccinated (51.90 ± 87.60 BAU/ml) individuals. Some unvaccinated individuals had anti-SARS-CoV-2 antibodies, which could be due to asymptomatic or symptomatic infection without history of COVID-19 realising, although their mean antibody titers were certainly lower than those in the 2-dose vaccinated group. Approximately 56% of vaccinated individuals had antibody titers above 60 BAU/mL (as a cut-off for protective threshold), a significantly higher proportion than unvaccinated individuals. In conclusion, vaccination with two doses increased anti-SARS-CoV-2 antibodies which resulted in enhanced immunity against symptomatic COVID-19.
印度尼西亚于 2021 年 1 月开始部署 COVID-19 疫苗,优先为医护人员、老年人和有合并症的人等高危人群接种,由于疫苗供应有限,最后为普通公众接种。我们的研究旨在评估接种过两剂疫苗与未接种疫苗的印度尼西亚人的抗体反应。研究设计为一项队列研究,涉及 46 名未接种者和 23 名三个多月前接种过第二剂阿斯利康疫苗的人。IgG抗体的定性和定量检测方法包括快速RI-GHA和ELISA测试。结果显示,通过快速 RI-GHA 试验定性检测出的阳性 IgG 抗体在接种疫苗者中(60.9%)明显高于未接种者(26.1%)。使用 ELISA 检测法,所有接种者的定性抗体均呈阳性(临界值≥4.33 BAU/mL),接种者抗 SARS-CoV-2 s-RBD IgG 的平均定量滴度(157.06±238.68 BAU/mL)明显高于未接种者(51.90±87.60 BAU/ml)。一些未接种者有抗SARS-CoV-2抗体,这可能是由于无症状或无症状感染而没有COVID-19病史,尽管他们的平均抗体滴度肯定低于2剂疫苗接种组。约 56% 的接种者抗体滴度超过 60 BAU/mL(作为保护阈值的临界值),这一比例明显高于未接种者。总之,接种两剂疫苗可增加抗 SARS-CoV-2 抗体,从而增强对无症状 COVID-19 的免疫力。
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引用次数: 0
Abrupt introduction of distance learning during the covid-19 pandemic: What psychological impact on teachers? 在科维德-19 大流行病期间突然引入远程学习:对教师的心理有何影响?
IF 0.6 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-01-01 eCollection Date: 2023-12-27 DOI: 10.4081/jphia.2024.2786
Hanane Aissaoui, Mariam Atassi, Asmae Lekfif, Mohammed Amine Bouazzaoui, Asmae Yeznasni, Sanae Sabbar, Naima Abda

As soon as the COVID-19 pandemic appeared, the Moroccan education ministry decided to adopt distance learning (DL). Our target was to study the psychological impact of DL on Moroccan teachers during the pandemic. This cross-sectional study used an online questionnaire based on the Hospital Anxiety and Depression Scale. Among 148 responses, 64.9% were women, and the average age was 41.1±11.5 years. 79.1% participated in DL, 58.8% were required to acquire DL tools and 71.6% had never received DL training. Between the start and the end of confinement, we noticed a decrease in the motivation of teachers.36.2% had definite depressive symptomatology and 41.3% had certain anxiety symptomatology with a significant predominance in women. The frequencies of depression and anxiety were higher in those who had participated in DL, but the association was not significant. Depression was significantly frequent among teachers who were obliged to acquire tools to practice DL P=0.02, those who had never received training DL P=0.046, and those who were not satisfied with the situation P=0.03. We didn't find a direct association between DL and anxiety and depression, which the small sample size may explain, but we did find an association with the variables related to DL.

COVID-19 大流行一出现,摩洛哥教育部就决定采用远程学习(DL)。我们的目标是研究大流行期间远程学习对摩洛哥教师的心理影响。这项横断面研究使用了基于医院焦虑和抑郁量表的在线问卷。在 148 份答卷中,64.9% 为女性,平均年龄为 41.1±11.5 岁。79.1%的人参加了 DL,58.8%的人需要获得 DL 工具,71.6%的人从未接受过 DL 培训。从禁闭开始到结束,我们注意到教师的积极性有所下降。36.2%的教师有明确的抑郁症状,41.3%的教师有一定的焦虑症状,其中女性明显占多数。参加过 DL 的教师抑郁和焦虑的频率较高,但相关性并不显著。在必须获得工具才能进行 DL 实践的教师、从未接受过 DL 培训的教师和对现状不满意的教师中,抑郁的发生率明显较高,分别为 P=0.02、P=0.046 和 P=0.03。我们没有发现 DL 与焦虑和抑郁之间的直接联系,这可能是由于样本量较小的缘故,但我们确实发现了与 DL 相关变量之间的联系。
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Journal of Public Health in Africa
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