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Survival Analysis of the Geriatric Population having Multiple Diseases in the Jammu District, J and K, India 印度 J 和 K 查谟地区患有多种疾病的老年人口的生存分析
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 DOI: 10.4103/ijcm.ijcm_904_22
V. Shivgotra, Manjeet Kumar, Himani Nanda
Aging is a complex, multifactorial, and inevitable process, which begins before birth and continues throughout the life. Multimorbidity prevailing among the geriatric population is an important health challenge for most of the developing countries. To examine the effect of gender and increasing age on the survival of the geriatric population suffering from multimorbidity. A cross-sectional study was conducted among the geriatric population of the Jammu district, J and K, using multistage sampling procedure, and the analysis was conducted using the Kaplan-Meier method and survival analysis using software IBM SPSS version 24.0. Our study included 1150 study subjects, of whom 610 (53%) were males and 540 (47%) were females, respectively. It was indicated that the probability for the survival of the study population suffering from morbidity belonging to 60–64 years was higher than the survival of the geriatric population belonging to other age-groups or we can say that survival probability of the geriatric population suffering from morbidities decreases with the increase in age. Also, it was reported that probability for the survival of the female geriatric population suffering from morbidity was slightly higher than the survival of the male geriatric population. Gender had no significant effect on survival of the geriatric population suffering from morbidities, whereas baseline age had a significant effect on the survival of the geriatric population suffering from morbidities as their survival probability decreases with the increase in age.
老龄化是一个复杂的、多因素的和不可避免的过程,它始于出生前,并持续一生。老年人口中普遍存在的多病症是大多数发展中国家面临的重要健康挑战。为了研究性别和年龄的增长对患有多病的老年人群生存的影响。我们采用多阶段抽样程序对查谟地区的老年人口进行了横断面研究,并使用 IBM SPSS 24.0 版软件进行了 Kaplan-Meier 法和生存分析。我们的研究包括 1150 名研究对象,其中男性 610 人(占 53%),女性 540 人(占 47%)。研究结果表明,60-64 岁发病人群的存活概率高于其他年龄组的老年发病人群,或者说,老年发病人群的存活概率随着年龄的增长而降低。另据报道,女性老年病患者的存活概率略高于男性老年病患者。性别对老年病患者的存活率没有明显影响,而基线年龄对老年病患者的存活率有明显影响,因为他们的存活率随着年龄的增加而降低。
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引用次数: 0
Association between COVID-19 Vaccination (ChAdOx1-S) and Thromboembolic, Thrombocytopenic, Hemorrhagic Events: A Systematic Review and Meta-analysis of Analytical Epidemiological Studies 接种 COVID-19 疫苗 (ChAdOx1-S) 与血栓栓塞、血小板减少和出血事件之间的关系:流行病学分析研究的系统回顾和元分析
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 DOI: 10.4103/ijcm.ijcm_676_23
R. Vaman, Muthusamy S. Kumar, K. Jeyashree, Ashok Periasami, RizwanSuliankachi Abdulkader, Manoj V. Murhekar
We conducted a systematic review of analytical epidemiological studies to assess the association between ChAdOx1-S vaccination and thromboembolic, thrombocytopenic, and hemorrhagic events. We searched Medline, Embase, Google Scholar, WHO-COVID-19 database, and medRxiv for studies evaluating the association between ChAdOx1-S and vascular events. Primary outcomes of interest were cerebral venous sinus thrombosis, peripheral venous thrombosis (PVT), and thrombocytopenia. Two independent reviewers screened for eligible studies, extracted data, and assessed the risk of bias. The DerSimonian-Laird random effects model was used to pool the incidence rate ratios (IRRs) separately for the first and second doses. Heterogeneity was assessed using I2 statistics. Twenty studies were included, of which 11 were self-controlled case series, and nine were cohort studies (254 million participants). Pooling of 17 studies showed a higher risk of cerebrovascular thrombosis (IRR = 3.5, 95% CI = 2.2–5.4, I2 = 79%), PVT (IRR = 2.0, 95% CI = 1.1–3.5, I2 = 95%) and thrombocytopenia (IRR = 1.6, 95% CI = 1.4–1.9, I2 = 93%) among those who received ChAdOx1-S vaccination as compared to controls. No increased risk was seen after the second dose or for secondary outcomes. There is moderate-to-high certainty of the evidence for the increased risk of cerebral venous sinus thrombosis, PVT, and thrombocytopenia following the first dose of the ChAdOx1-S vaccine. Systematic Review Registration: PROSPERO CRD42022372768.
我们对流行病学分析研究进行了系统回顾,以评估接种 ChAdOx1-S 疫苗与血栓栓塞、血小板减少和出血事件之间的关联。我们在 Medline、Embase、Google Scholar、WHO-COVID-19 数据库和 medRxiv 中检索了评估 ChAdOx1-S 与血管事件之间关系的研究。主要研究结果为脑静脉窦血栓、外周静脉血栓(PVT)和血小板减少。两位独立审稿人筛选了符合条件的研究,提取了数据并评估了偏倚风险。采用DerSimonian-Laird随机效应模型分别对第一剂和第二剂的发病率比(IRR)进行汇总。异质性采用I2统计量进行评估。共纳入 20 项研究,其中 11 项为自控病例系列研究,9 项为队列研究(2.54 亿参与者)。17 项研究的汇总结果显示,与对照组相比,接种 ChAdOx1-S 疫苗的人群发生脑血管血栓(IRR = 3.5,95% CI = 2.2-5.4,I2 = 79%)、PVT(IRR = 2.0,95% CI = 1.1-3.5,I2 = 95%)和血小板减少症(IRR = 1.6,95% CI = 1.4-1.9,I2 = 93%)的风险较高。接种第二剂后或次要结果的风险未见增加。接种第一剂 ChAdOx1-S 疫苗后,脑静脉窦血栓形成、PVT 和血小板减少的风险增加的证据具有中度到高度的确定性。 系统综述注册:PREMCOCO CRD42022372768。
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引用次数: 0
High-risk HPV Prevalence Estimates among Older Patients: Implications for Cervical Cancer Screening Programs 高危 HPV 在老年患者中的流行率估计值:宫颈癌筛查计划的意义
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 DOI: 10.4103/ijcm.ijcm_800_22
S. Mittal, Yamini Kansal, Bhumika Singh, Vineeta Gupta
Due to the heterogeneity of existing studies and wide range of human papilloma virus (HPV) prevalence in India, further research into the incidence of HR-HPV and its spectrum of genotypes is essential to develop screening policies. This study aimed to determine the incidence and demographic distribution of HR-HPV among cisgender female patients attending a tertiary care facility in North India. This study was conducted in the Department of Obstetrics and Gynaecology, SGRR Institute of Medical and Health Sciences, Dehradun, India. HPV-DNA test results of 653 female patients were assessed for HR-HPV positivity, genotyping, and age-based differences via Chi-square analysis. Overall prevalence of HR-HPV was 4.90%, HPV-16 was 1.37%, HPV-18 was 0.76%, and HPV non-16,18 was 2.7%. In patients ≤ 50 years, prevalence of HPV-16 was 0.97%, HPV-18 was 0.38%, and HR-HPV non-16,18 was 2.71%. In patients > 50 years, prevalence of HPV-16 was 2.89%, HPV-18 was 2.17%, and HR-HPV non-16,18 was 2.89%. The difference in the prevalence of HPV-16,18 between patients ≤ and > 50 years was found to be highly statistically significant (P = 0.007485). The difference in the prevalence of total HR-HPV between patients ≤ and > 50 years was not found to be statistically significant (P = 0.059905). Our study’s finding of higher HR-HPV positivity rates in patients > 50 years emphasizes the need for continued HR-HPV-DNA-based screening of this cohort. With widespread use in post-menopausal patients, HPV screening can serve as an important armamentarium in the fight against cervical cancer.
由于印度现有研究的异质性和人类乳头瘤病毒(HPV)流行的广泛性,进一步研究 HR-HPV 的发病率及其基因型谱对于制定筛查政策至关重要。本研究旨在确定在印度北部一家三级医疗机构就诊的顺性别女性患者中 HR-HPV 的发病率和人口分布情况。 本研究在印度德拉敦 SGRR 医疗卫生科学研究所妇产科进行。通过卡方分析评估了 653 名女性患者的 HR-HPV 阳性、基因分型和年龄差异。 HR-HPV总患病率为4.90%,HPV-16为1.37%,HPV-18为0.76%,HPV non-16、18为2.7%。在年龄小于 50 岁的患者中,HPV-16 的感染率为 0.97%,HPV-18 为 0.38%,HR-HPV non-16,18 为 2.71%。在年龄大于 50 岁的患者中,HPV-16 的感染率为 2.89%,HPV-18 为 2.17%,HR-HPV non-16,18 为 2.89%。研究发现,HPV-16,18 在年龄小于和大于 50 岁的患者中的流行率差异具有高度统计学意义(P = 0.007485)。在≤50 岁和大于 50 岁的患者中,总 HR-HPV 感染率的差异无统计学意义(P = 0.059905)。 我们的研究发现,50 岁以上患者的 HR-HPV 阳性率较高,这强调了继续对这部分人群进行 HR-HPV DNA 筛查的必要性。随着 HPV 筛查在绝经后患者中的广泛应用,它将成为对抗宫颈癌的重要手段。
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引用次数: 0
Clinical Spectrum of Dermatological Disorders at an Urban Health Center in East Delhi 东德里一家城市医疗中心的皮肤病临床表现
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 DOI: 10.4103/ijcm.ijcm_940_22
Sonika Soni, Taru Garg, Anita Acharya, Rashmi Sarkar
Dermatological disorders constitute a significant proportion of primary health care (PHC) setups. The pattern of dermatological disorders varies among different countries and different parts of the same country owing to climatic and geographical variations, level of education, access to health care, etc. To study the clinical spectrum of patients presenting with dermatological disorders at an urban health center (UHC) in East Delhi. To identify the various risk factors associated with dermatological disorders in study subjects. A total of 1,148 patients who reported skin diseases for the first time at the Dermatology Outpatient Clinic at UHC in East Delhi were recruited. Detailed demographic data, history, and examination and potential risk factors of skin diseases (socioeconomic status, level of education, occupation, comorbidities, and addictions) were recorded on a predesigned proforma. A total of 616 (53.7%) patients had infectious dermatoses and 532 (46.3%) had non-infectious dermatoses. Among the infectious dermatoses, fungal diseases (44.8%) were the most common followed by parasitic infections (31.17%) and bacterial infections (9.74%). Among the non-infectious group, eczematous disorders (28.01%) were the most common, followed by pigmentary disorders (21.62%) and acne (19.55%). A significant association between level of education, occupation, and comorbidities with the distribution of infectious and non-infectious dermatoses was found. As a significant proportion of patients with a vivid spectrum of dermatological disorders present at the PHC setups, therefore dermatologists supervise that specialty clinics should be held regularly at these centers along with the availability of all the basic investigations to aid diagnosis and management.
皮肤病在初级卫生保健(PHC)中占有很大比例。由于气候和地理差异、教育水平、医疗条件等原因,不同国家和同一国家不同地区的皮肤病发病模式各不相同。研究东德里城市医疗中心(UHC)皮肤病患者的临床表现。确定研究对象中与皮肤病相关的各种风险因素。共招募了 1,148 名首次到东德里 UHC 皮肤科门诊就诊的皮肤病患者。详细的人口统计学数据、病史、检查和皮肤病的潜在风险因素(社会经济地位、教育水平、职业、合并症和嗜好)都被记录在事先设计好的表格中。共有 616 名(53.7%)患者患有感染性皮肤病,532 名(46.3%)患者患有非感染性皮肤病。在感染性皮肤病中,最常见的是真菌病(44.8%),其次是寄生虫感染(31.17%)和细菌感染(9.74%)。在非感染性皮肤病中,最常见的是湿疹(28.01%),其次是色素性皮肤病(21.62%)和痤疮(19.55%)。研究发现,受教育程度、职业和合并症与感染性和非感染性皮肤病的分布有明显关联。由于有相当一部分患有各种皮肤病的患者在初级保健中心就诊,因此皮肤科医生建议这些中心应定期开设专科门诊,并提供各种基本检查,以帮助诊断和治疗。
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引用次数: 0
Trend, Pattern, and Prevalence of Adverse Pregnancy Outcomes among Women of Reproductive Age in India, 1992–2021 1992-2021 年印度育龄妇女不良妊娠结局的趋势、模式和发生率
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 DOI: 10.4103/ijcm.ijcm_337_23
P. Swain, Anmol Jena
Adverse pregnancy outcomes (APOs) are the most important vital statistics used to assess maternal health and child health statistics. They are an indicator of the quality of maternal and child health care services, i.e., antenatal care, intrapartum care, and medical services. The objective of the study is to analyze the trend, pattern, and prevalence of APOs among women of reproductive age group at the national level over successive NFHS rounds. The current study uses data from the National Family Health Survey (NFHS), conducted during 1992–2021. The study uses geo-spatial mapping techniques through QGIS software and report analysis to arrive at definitive conclusions. The study finds that the incidence of APOs among women of reproductive age (15–49 years) has increased over the years. Twenty states and union territories have APOs that are below the national average. On the other hand, States like Madhya Pradesh, Meghalaya, Sikkim, Goa, Maharashtra, Andhra Pradesh, Karnataka, and Kerala have witnessed their APOs worsening as per NFHS-5 vis-à-vis NFHS-4. The study also finds that apart from the Himalayan belt and the east coast of India, APOs are more prominent in the contiguous regions adjoining these areas. The findings of the study have thrown on very interesting facts. Despite rapid economic development during the intervening period between NFHS-4 and NFHS-5, rising APOs are a testament to the fact that the policymakers in the country need to be more target-oriented and get their acts together.
不良妊娠结局(APOs)是用于评估孕产妇健康和儿童健康统计的最重要的生命统计数据。它们是衡量母婴保健服务(即产前护理、产中护理和医疗服务)质量的指标。 本研究的目的是分析连续几轮全国人口与健康调查期间全国育龄妇女中 APO 的趋势、模式和流行率。本研究使用的数据来自 1992-2021 年开展的全国家庭健康调查(NFHS)。研究通过 QGIS 软件使用地理空间绘图技术和报告分析得出明确结论。 研究发现,育龄妇女(15-49 岁)的 APO 发病率逐年上升。有 20 个邦和中央直辖区的 APOs 低于全国平均水平。另一方面,中央邦、梅加拉亚邦、锡金邦、果阿邦、马哈拉施特拉邦、安得拉邦、卡纳塔克邦和喀拉拉邦等邦,根据 NFHS-5 与 NFHS-4 的比较,APOs 情况有所恶化。研究还发现,除喜马拉雅山带和印度东海岸外,APO 在与这些地区毗邻的毗连地区更为突出。 研究结果揭示了非常有趣的事实。尽管在 NFHS-4 和 NFHS-5 之间的间隔期内经济发展迅速,但 APOs 的上升证明了一个事实,即印度的政策制定者需要更加以目标为导向,并振作起来。
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引用次数: 0
Super-Speciality in India: A Boon or Bane? 印度的超级专科:是福还是祸?
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 DOI: 10.4103/ijcm.ijcm_731_23
Shivanee Kumari, B. Reddy, Yogendra Malik, Suresh B. Math
In the past few decades, super-specialization has gained popularity in many medical disciplines. It provides professionals with a sturdy platform for advanced research and helps to deliver focused and extensive care in the fields of trauma and critical care, which can translate into good clinical outcomes for patients. Although this drift may bring about novel research opportunities, it may limit the number of doctors attending to the basic healthcare needs of the population. India is still struggling to provide primary healthcare services to its population. Super-specialization is a highly technology-driven industry, the costs of which our public health system cannot endure in the present settings. The current demand in India, where basic priorities are yet to be met, is to increase health awareness, provide basic healthcare facilities, and generate interest among medical professionals in providing general health services, especially in rural areas.
在过去几十年中,超级专业化在许多医学学科中得到了普及。它为专业人员提供了进行高级研究的坚实平台,并有助于在创伤和重症监护领域提供重点突出的广泛护理,从而为患者带来良好的临床疗效。尽管这种漂移可能会带来新的研究机会,但它可能会限制满足民众基本医疗需求的医生数量。印度仍在努力为民众提供初级医疗保健服务。超级专业化是一个高度技术驱动的行业,我们的公共卫生系统在目前的环境下无法承受其成本。在基本优先事项尚未得到满足的印度,目前的需求是提高人们的健康意识,提供基本的医疗保健设施,并激发医疗专业人员提供一般医疗服务的兴趣,特别是在农村地区。
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引用次数: 0
A Longitudinal Study of Acute Diarrhoeal Diseases Among Children Under Five Years in an Urban Area of Goa 果阿城市地区五岁以下儿童急性腹泻病纵向研究
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 DOI: 10.4103/ijcm.ijcm_382_22
Apika K Sawant, Nitin Y. Dhupdale
Acute diarrhoeal diseases (ADD) account for a large number of preventable deaths in India, especially in children less than five years who are more at risk than adults with respect to the degree of dehydration and complications. (1) To measure the incidence of ADD among children under 5 years; (2) Determine risk factors associated among children; (3) Study treatment-seeking behaviour of their mothers. Community-based, prospective, longitudinal study conducted in an urban area of Goa. 250 children enrolled in the study with their mothers by stratified random sampling technique, conducted house-to-house visits every three months and mothers were interviewed with pre-tested semi-structured questionnaire. The duration of study was one year from January to December 2018. Data entered using EpiData Entry Client®, Analysed using SPSS® software version 22. Student’s t-tests and Chi-square tests were used. The incidence of ADD was 0.124 episodes/child/year. Significant association was noted between ADD in children and certain socio-demographic factors like child’s sex, birth order, birth weight, immunization status, malnutrition, mother’s age group, mother’s education, and mothers’ hygiene practices. Efforts should be made to educate all mothers about the seeking timely treatment, awareness about home-based management and their types, awareness of ORS, zinc, importance of hygienic practices like hand washing for mother and child.
在印度,急性腹泻病(ADD)造成大量可预防的死亡,尤其是五岁以下儿童,他们在脱水程度和并发症方面比成人更危险。(1) 测量 5 岁以下儿童的脱水症发病率;(2) 确定儿童的相关风险因素;(3) 研究其母亲寻求治疗的行为。在果阿的一个城市地区开展基于社区的前瞻性纵向研究。 通过分层随机抽样技术将 250 名儿童及其母亲纳入研究,每三个月进行一次家访,并通过预先测试的半结构式问卷对母亲进行访谈。研究为期一年,从 2018 年 1 月至 12 月。数据使用 EpiData Entry Client® 输入,使用 SPSS® 软件 22 版进行分析。采用学生 t 检验和卡方检验。 注意力缺失症的发病率为 0.124 次/儿童/年。研究发现,儿童注意力缺失症与某些社会人口因素(如儿童性别、出生顺序、出生体重、免疫接种状况、营养不良、母亲年龄组别、母亲教育程度和母亲的卫生习惯)有显著关联。 应努力教育所有母亲寻求及时治疗、了解家庭疗法及其类型、了解口服补液盐、锌、母婴洗手等卫生习惯的重要性。
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引用次数: 0
Diabetes Mellitus as a Risk Factor for Tuberculosis: A Community Based Case Control Study 糖尿病是肺结核的危险因素:基于社区的病例对照研究
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 DOI: 10.4103/ijcm.ijcm_86_23
P. Kokiwar, Arun K. Soodi Reddy
Prevention of diabetes in the general population can help reduce the incidence of tuberculosis. Hence it is necessary to document that diabetes is strongly associated with tuberculosis as a risk factor. To study if diabetes is associated with tuberculosis compared to controls. A community based case-control study was carried out. 215 newly diagnosed cases of tuberculosis on treatment for not more than three months were selected randomly from the randomly selected tuberculosis unit. 215 neighbourhood controls were selected. They were matched for the age group of ± 10 years and sex. Fasting blood sugar (FBS) was estimated using a glucometer. Tobacco chewing, residence and family history of TB were significantly more in cases (P < 0.05). Mean BMI was significantly lower in cases compared to controls. The proportion of TB cases among the known cases of diabetes was 67% compared to 33% in controls, which was statistically significant. Mean FBS was significantly higher in cases compared to controls (P < 0.05). The odds of cases being diabetic was 2.456 times more than those of controls. On binary logistic regression, diabetes was an independent risk factor for tuberculosis. Other independent risk factors were tobacco chewing, and family history of TB. Family history of tuberculosis, and tobacco chewing were positively associated with tuberculosis whereas body mass index was negatively associated with tuberculosis. Diabetes was significantly associated with tuberculosis.
在普通人群中预防糖尿病有助于降低结核病的发病率。因此,有必要记录糖尿病作为一种风险因素与肺结核密切相关。 为了研究与对照组相比,糖尿病是否与肺结核有关。 我们开展了一项基于社区的病例对照研究。从随机选取的结核病治疗单位中随机抽取了 215 例新确诊的结核病病例,这些病例正在接受不超过三个月的治疗。同时还选取了 215 名邻近地区的对照者。他们的年龄组(± 10 岁)和性别匹配。空腹血糖(FBS)用血糖仪估算。 病例中咀嚼烟草者、居住地和结核病家族史明显增多(P < 0.05)。病例的平均体重指数明显低于对照组。在已知的糖尿病病例中,肺结核病例的比例为 67%,而对照组为 33%,差异有统计学意义。病例的平均 FBS 明显高于对照组(P < 0.05)。病例患糖尿病的几率是对照组的 2.456 倍。二元逻辑回归结果显示,糖尿病是肺结核的独立风险因素。其他独立风险因素包括咀嚼烟草和结核病家族史。 肺结核家族史和咀嚼烟草与肺结核呈正相关,而体重指数与肺结核呈负相关。糖尿病与肺结核密切相关。
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引用次数: 0
Erratum: Intimate Partner Violence Webinar’s Public Health Implication 勘误:亲密伴侣暴力网络研讨会的公共卫生意义
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 DOI: 10.4103/ijcm.ijcm_465_24
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引用次数: 0
Nuances of Cohort Studies and Risk Ratio 队列研究和风险比的细微差别
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-01 DOI: 10.4103/ijcm.ijcm_640_23
P. Doke
Post-graduate students and faculty usually conduct case-control studies. However, sometimes they conduct cohort studies that are short-duration. Most investigators enroll the participants in two groups according to the exposure. Then, follow the participants for some duration. At the end of the study, relative risk is calculated, and the work is published in some journal. The exposure may be one time, which may or may not be quantified. The follow-up duration may not be participant-specific, and differential follow-up does not exist. The author has given three examples: the first example of consanguineous marriages and congenital disabilities, the second example of the ABO blood group system and childhood asthma, and the third example of insecticide spraying and stillbirth. In the given examples, cumulative or density incidence cannot be calculated in a true sense and, therefore, risk ratio. Even estimating the incidence of outcome variables in some studies is not appropriate. Risk ratio calculation in such scenarios is questionable because exposure quantification, follow-up period, and combination are the limiting factors. In case-control studies, the prevalence ratio is calculated, which is analogous to relative risk. The author suggests that, in such circumstances, prevalence ratio calculation will be more appropriate.
研究生和教师通常进行病例对照研究。不过,有时他们也会进行短期的队列研究。大多数研究者根据暴露情况将参与者分为两组。然后,对参与者进行一段时间的跟踪调查。研究结束后,计算相对风险,并在一些期刊上发表研究成果。暴露可能是一次性的,可以量化,也可以不量化。随访时间可能不是针对特定参与者的,也不存在差别随访。作者举了三个例子:第一个例子是近亲结婚与先天残疾,第二个例子是 ABO 血型系统与儿童哮喘,第三个例子是喷洒杀虫剂与死胎。在上述例子中,无法计算真正意义上的累积或密度发病率,因此也无法计算风险比。在某些研究中,即使对结果变量的发生率进行估计也是不恰当的。在这种情况下,风险比的计算是有问题的,因为暴露量化、随访期和组合是限制因素。在病例对照研究中,计算的是患病率比值,类似于相对风险。作者建议,在这种情况下,流行率计算更为合适。
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引用次数: 0
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Indian Journal of Community Medicine
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