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Editorial Commentary. 社论评论。
IF 0.8 Q4 UROLOGY & NEPHROLOGY Pub Date : 2025-01-01 Epub Date: 2024-09-18 DOI: 10.1097/UPJ.0000000000000695
Nir Tomer, Johnathan Alexander Khusid
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引用次数: 0
Editorial Commentary. 社论评论。
IF 0.8 Q4 UROLOGY & NEPHROLOGY Pub Date : 2025-01-01 Epub Date: 2024-10-11 DOI: 10.1097/UPJ.0000000000000712
J Stephen Jones
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引用次数: 0
Integrated Care in a Large Public System Improves Simple Kidney Stone Management. 大型公共系统中的综合护理改善了简单的肾结石管理。
IF 0.8 Q4 UROLOGY & NEPHROLOGY Pub Date : 2025-01-01 Epub Date: 2024-10-11 DOI: 10.1097/UPJ.0000000000000721
Cecilia Wada, Aaron A Laviana, Tarah Woodle, Parth Patel, Steven E Lerman, Jeremy Blumberg, Jamal Nabhani, Benjamin Waterman, Jonathan Bergman

Introduction: In the Los Angeles County Department of Health Services-the second largest public health care system in the United States-clinical integration allows specialists and primary care providers to collaboratively provide specialty care. We used time-driven activity-based costing to compare patient burden and cost of kidney stone diagnosis, workup, and management with and without clinical integration.

Methods: We interviewed and observed teams of physicians and staff to understand workflow practices and personnel, space, material, and device requirements for stone care in the 2 models. We created process maps that outline the entire arc of care and used time-driven activity-based costing to calculate the all-inclusive costs of kidney stone diagnosis, workup, and scheduling for surgical treatment.

Results: The total cost of kidney stone treatment per stone episode in the integrated pathway was $499.04, compared with $699.81 in the traditional, nonintegrated pathway, a difference of 29%. The number of steps needed to arrive at operating room scheduling was 11 with integration and 14 without it.

Conclusions: Clinical integration resulted in more efficient and cost-effective care from patient, provider, and health system perspectives. Integrated care may improve access to specialty care and increase the value of care and reduce treatment burden on patients.

目标:在美国第二大公共医疗保健系统--洛杉矶县卫生服务部,临床整合使专科医生和初级医疗服务提供者能够合作提供专科医疗服务。我们采用基于时间驱动活动的成本计算方法,比较了有临床整合和没有临床整合的肾结石诊断、检查和管理的患者负担和成本:方法:我们采访并观察了医生和员工团队,以了解两种模式下结石治疗的工作流程实践以及对人员、空间、材料和设备的要求。我们绘制了流程图,勾勒出整个治疗过程,并使用时间驱动的活动成本法计算肾结石诊断、检查和手术治疗安排的总成本:结果:在综合路径中,每例肾结石病例的治疗总成本为 499.04 美元,而在传统非综合路径中为 699.81 美元,两者相差 29%。整合后,手术室排期所需的步骤为 11 个,而未整合时为 14 个:结论:从患者、医疗服务提供者和医疗系统的角度来看,临床整合带来了更高效、更具成本效益的医疗服务。整合护理可改善专科护理的可及性,提高护理价值,减轻患者的治疗负担。
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引用次数: 0
Detection of Germline Variants in Patients With Localized and Metastatic Prostate Cancer Through Guideline-Based Testing. 通过基于指南的测试检测局部和转移性前列腺癌患者的基因变异。
IF 0.8 Q4 UROLOGY & NEPHROLOGY Pub Date : 2025-01-01 Epub Date: 2024-10-09 DOI: 10.1097/UPJ.0000000000000727
Sophia M Abusamra, Marissa A Solorzano, Jake Quarles, Mallory Luke, Milan Patel, Randy Vince, Ralph Jiang, Joshua Volin, Michelle F Jacobs, Samuel D Kaffenberger, Simpa S Salami, Phillip Palmbos, Megan E V Caram, Brent K Hollenbeck, Ganesh S Palapattu, Sofia D Merajver, Elena M Stoffel, Jason Hafron, Todd M Morgan, Zachery R Reichert

Introduction: There is increasing awareness that patients with prostate cancer frequently harbor germline variants that may carry important implications for them and their family members. Given the variable clinical guidelines, there remains a need to better understand which patients with prostate cancer are likely to harbor pathogenic or likely pathogenic (P/LP) germline variants. We sought to understand factors associated with P/LP germline variants in patients with metastatic or localized prostate cancer qualifying for National Comprehensive Cancer Network genetic testing criteria.

Methods: Patients diagnosed with prostate cancer were offered genetic testing in accordance with National Comprehensive Cancer Network guidelines. Patient-level factors, including demographic, clinical, and pathologic data, were tracked in a prospectively collected registry. The association of the presence of a P/LP variant in germline testing results with patient-level factors was assessed using univariate and multivariate logistic regression. Variables were tested for overall significance with χ2 tests.

Results: Five hundred five patients underwent germline testing and had clinical data available. Rates of P/LP germline variants were 7.6% (20/264) in patients with metastatic disease and 11.2% (27/241) in patients with localized disease. The most prevalent P/LP variants were CHEK2 (34%), BRCA2 (22%), ATM (10%), and HOXB13 (10%).

Conclusions: In this cohort of patients undergoing guideline-informed germline testing, P/LP germline variants were found in similar proportions across all age ranges and clinical characteristics. Only age at genetic testing for patients with metastatic disease was demonstrated to be predictive of the presence of a P/LP germline variant, highlighting the challenges associated with refining current clinical testing guidelines.

目的:越来越多的人意识到,前列腺癌患者经常携带种系变异,这些变异可能会对患者及其家庭成员产生重要影响。鉴于临床指南各不相同,仍有必要更好地了解哪些前列腺癌患者可能携带致病或可能致病(P/LP)的种系变异。我们试图了解符合 NCCN 基因检测标准的转移性或局部性前列腺癌患者中与 P/LP 基因变异相关的因素:根据美国国家综合癌症网络(NCCN)指南,对确诊为前列腺癌的患者进行基因检测。在一个前瞻性收集的登记册中追踪了患者层面的因素,包括人口学、临床和病理学数据。采用单变量和多变量逻辑回归评估了种系检测结果中出现的 P/LP 变异与患者水平因素之间的关联。采用卡方检验对变量进行总体显著性检验:结果:505 名患者接受了种系检测并提供了临床数据。转移性疾病患者的 P/LP 基因变异率为 7.6%(20/264),局部疾病患者的 P/LP 基因变异率为 11.2%(27/241)。最常见的P/LP变异是CHEK2(34%)、BRCA2(22%)、ATM(10%)和HOXB13(10%):在这批接受指导性基因检测的患者中,P/LP 基因变异在所有年龄段和临床特征中的发现比例相似。只有对转移性疾病患者进行基因检测时的年龄才能预测是否存在P/LP种系变异,这凸显了完善当前临床检测指南所面临的挑战。
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引用次数: 0
Editorial Commentary. 编辑评论。
IF 0.8 Q4 UROLOGY & NEPHROLOGY Pub Date : 2025-01-01 Epub Date: 2024-10-29 DOI: 10.1097/UPJ.0000000000000738
Halle E Foss, Kevin Koo
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引用次数: 0
Editorial Commentary. 社论评论。
IF 0.8 Q4 UROLOGY & NEPHROLOGY Pub Date : 2025-01-01 Epub Date: 2024-09-17 DOI: 10.1097/UPJ.0000000000000688
J Stephen Jones
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引用次数: 0
Revisiting Fournier Gangrene: A Contemporary Epidemiological Perspective vs Perineal Cellulitis. 重新审视福尼尔坏疽:当代流行病学视角对比会阴蜂窝织炎。
IF 0.8 Q4 UROLOGY & NEPHROLOGY Pub Date : 2025-01-01 Epub Date: 2024-10-02 DOI: 10.1097/UPJ.0000000000000724
Behzad Abbasi, Emily Hacker, Umar Ghaffar, Nizar Hakam, Kevin D Li, Sultan Alazzawi, Hiren V Patel, Benjamin N Breyer

Introduction: We conducted a population-based analysis of Fournier gangrene (FG) to compare risk factors and mortality with those of perineal cellulitis.

Methods: We analyzed National Inpatient Sample data (2016-2020) to identify FG and perineal cellulitis cases. Demographic, comorbidity, and procedural data were extracted. Logistic models assessed risk factors of FG diagnosis and mortality.

Results: A total of 73,472 cellulitis and 9326 FG cases were identified corresponding to 74,905 (range, 63,050-79,165) and 9115 (range, 7925-11,080) median yearly weighted cases, respectively. FG diagnosis vs cellulitis was positively associated with Native American race (odds ratio [OR], 1.46; 95% CI, 1.19-1.79), weekend (OR, 1.12; 95% CI, 1.06-1.18) or December (OR, 1.33; 95% CI, 1.22-1.44) admissions, diabetes mellitus (OR, 2.51; 95% CI, 2.38-2.64), and malignancy (OR, 2.29; 95% CI, 2.07-2.54). Conversely, Hispanic (OR, 0.79; 95% CI, 0.74-0.85) and Asian/Pacific Islander races (OR, 0.83; 95% CI, 0.69-0.99) and the highest household income quartile (OR, 0.84; 95% CI, 0.78-0.90) were linked to a reduced likelihood of FG diagnosis. Elevated mortality risks were observed with female sex (OR, 1.33; 95% CI, 1.08-1.63), Native American ethnicity (OR, 2.29; 95% CI, 1.14-4.57), and procedural frequency (OR, 1.27; 95% CI, 1.24-1.3) among FG cases.

Conclusions: Various patient and clinical factors are linked to the development and mortality of FG compared with perineal cellulitis. Improved access to care and understanding of FG can enhance patient outcomes.

简介:我们对福尼尔坏疽进行了人群分析,以比较会阴蜂窝织炎的风险因素和死亡率:我们对福尼尔坏疽进行了一项基于人群的分析,以比较其与会阴蜂窝织炎的风险因素和死亡率:我们分析了全国住院患者样本数据(2016-2020 年),以确定 Fournier 坏疽和会阴蜂窝织炎病例。我们提取了人口统计学、合并症和手术数据。逻辑模型评估了福尼尔坏疽诊断和死亡率的风险因素:结果:共发现 73,472 例蜂窝织炎和 9,326 例福尼尔坏疽病例,年加权中位数分别为 74,905 例(范围为 63,050-79,165 例)和 9,115 例(范围为 7,925-11,080 例)。Fournier 坏疽诊断与蜂窝组织炎呈正相关,这与美国本土人种(OR 1.46,95% CI 1.19-1.79)、周末(OR 1.12,95% CI 1.06-1.18)或十二月(OR 1.33,95% CI 1.22-1.44)入院、糖尿病(OR 2.51,95% CI 2.38-2.64)和恶性肿瘤(OR 2.29,95% CI 2.07-2.54)有关。相反,西班牙裔(OR 0.79,95% CI 0.74-0.85)、亚洲/太平洋岛民(OR 0.83,95% CI 0.69-0.99)和家庭收入最高的四分位数(OR 0.84,95% CI 0.78-0.90)与诊断为福尼尔坏疽的可能性降低有关。在 Fournier 坏疽病例中,女性(OR 1.33,95% CI 1.08-1.63)、美国原住民(OR 2.29,95% CI 1.14-4.57)和手术频率(OR 1.27,95% CI 1.24-1.3)的死亡率风险较高:结论:与会阴蜂窝织炎相比,各种患者和临床因素都与福尼尔坏疽的发生和死亡率有关。改善医疗服务和提高对福尼尔坏疽的认识可以改善患者的治疗效果。
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引用次数: 0
Editorial Comment. 编辑评论。
IF 0.8 Q4 UROLOGY & NEPHROLOGY Pub Date : 2025-01-01 Epub Date: 2024-10-12 DOI: 10.1097/UPJ.0000000000000715
Richard A Watson
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引用次数: 0
Patient-Centered Cost Saving and Positive Environmental Impact With the Introduction of Telehealth Services at a Single Center. 在一个中心引入远程医疗服务,以病人为中心节约成本并对环境产生积极影响。
IF 0.8 Q4 UROLOGY & NEPHROLOGY Pub Date : 2025-01-01 Epub Date: 2024-10-02 DOI: 10.1097/UPJ.0000000000000723
Vivian Wong, Jessica Cohen, Amanda Ingram, Edward Woods, Brian Mitchell, Brooke Bellamy, Tasha Posid, Irene Crescenze

Introduction: The aim of this study was to establish the patient-specific cost and time savings associated with telemedicine with the secondary environmental benefits of virtual visits within a tertiary referral center subspecialty urology clinic.

Methods: An electronic health record query was made of all urology telehealth visits that have occurred between April 10, 2020, and October 10, 2020, at a single academic center. We evaluated the cost of travel for an in-person visit based on zip code data. To adjust for productivity loss, the cost of missed work was added as either full-day or half-day-based distance and average compensation per day based on zip code data. Environmental impact was calculated using average CO2 emissions per mile not traveled.

Results: There were 6444 patients seen in the urology clinic through telehealth during the 6-month period. Urology patients traveled on average 69 ± 148 miles round trip for an appointment. The average cost savings per patient including the cost of gas and time away from work was $152.78 ± $105.90. Overall, over a 6-month period, the total cost savings was $984,534.73 for the 6444 patients seen through telemedicine. There was also a significant environmental impact of the decreased travel burden with 153.36 metric tons of CO2 emissions eliminated.

Conclusions: With the implementation of telehealth during the COVID-19 pandemic, patients have been able to save a substantial amount of time and money primarily driven by the decreasing work hours lost and cost of travel.

目的在三级转诊中心的泌尿科亚专科门诊中,确定与远程医疗相关的患者特定成本和时间节省情况,以及虚拟就诊的次要环境效益:方法: 我们对一家学术中心 2020 年 10 月 4 日至 2020 年 10 月 10 日期间发生的所有泌尿外科远程医疗就诊进行了电子健康记录查询。我们根据邮政编码数据评估了亲自就诊的旅行成本。为了对生产力损失进行调整,我们根据距离和邮政编码数据,将误工成本按全天或半天计算。对环境的影响是根据每英里未行驶的平均二氧化碳排放量计算得出的:在 6 个月的时间里,有 6444 名患者通过远程医疗在泌尿科诊所就诊。泌尿科患者预约就诊的平均往返里程为 69 ± 148 英里。包括油费和误工费在内,每位患者平均节省了 152.78 美元 ± 105.90 美元。总体而言,在 6 个月的时间里,通过远程医疗就诊的 6444 名患者共节省了 984,534.73 美元。旅行负担的减轻也对环境产生了重大影响,减少了 153.36 公吨的二氧化碳排放量:结论:在 COVID-19 大流行期间实施远程医疗后,患者能够节省大量时间和金钱,主要原因是减少了工时损失和差旅费用。
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引用次数: 0
Editorial Comment. 编辑评论。
IF 0.8 Q4 UROLOGY & NEPHROLOGY Pub Date : 2025-01-01 Epub Date: 2024-10-11 DOI: 10.1097/UPJ.0000000000000719
Wesley A Mayer
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引用次数: 0
期刊
Urology Practice
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