Pub Date : 2019-11-26DOI: 10.1007/s12018-019-09268-w
K. Barnhill, Morgan Devlin, L. Hewitson
{"title":"Bone Health and BMD Research in Pediatric and Adolescent Individuals with ASD: Current Data, Evaluation, and Next Steps","authors":"K. Barnhill, Morgan Devlin, L. Hewitson","doi":"10.1007/s12018-019-09268-w","DOIUrl":"https://doi.org/10.1007/s12018-019-09268-w","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"17 1","pages":"160 - 169"},"PeriodicalIF":1.8,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09268-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49572069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-25DOI: 10.1007/s12018-019-09269-9
C. Valero, Mª José Docampo García
{"title":"Bone Metabolism in Inflammatory Bowel Disease and Celiac Disease","authors":"C. Valero, Mª José Docampo García","doi":"10.1007/s12018-019-09269-9","DOIUrl":"https://doi.org/10.1007/s12018-019-09269-9","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"17 1","pages":"152 - 159"},"PeriodicalIF":1.8,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09269-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46883713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-20DOI: 10.1007/s12018-019-09267-x
P. Giraldo
{"title":"Current and Emerging Pharmacotherapy for Gaucher Disease","authors":"P. Giraldo","doi":"10.1007/s12018-019-09267-x","DOIUrl":"https://doi.org/10.1007/s12018-019-09267-x","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"17 1","pages":"142 - 151"},"PeriodicalIF":1.8,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09267-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45366003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-29DOI: 10.1007/s12018-019-09266-y
Jessica Sammut, Miriam Giordano Imbroll, Mark Gruppetta
{"title":"X-linked Hypophosphatemic Rickets: the Challenges of Treatment","authors":"Jessica Sammut, Miriam Giordano Imbroll, Mark Gruppetta","doi":"10.1007/s12018-019-09266-y","DOIUrl":"https://doi.org/10.1007/s12018-019-09266-y","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"17 1","pages":"138 - 141"},"PeriodicalIF":1.8,"publicationDate":"2019-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09266-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42003927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-19DOI: 10.1007/s12018-019-09264-0
N. Mathavan, O. Kennedy
{"title":"Skeletal Changes Associated with Osteoarthritis","authors":"N. Mathavan, O. Kennedy","doi":"10.1007/s12018-019-09264-0","DOIUrl":"https://doi.org/10.1007/s12018-019-09264-0","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"17 1","pages":"123 - 137"},"PeriodicalIF":1.8,"publicationDate":"2019-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09264-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46711908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-02DOI: 10.1007/s12018-019-09263-1
J. Miszkiewicz, Karen M Cooke
{"title":"Socio-economic Determinants of Bone Health from Past to Present","authors":"J. Miszkiewicz, Karen M Cooke","doi":"10.1007/s12018-019-09263-1","DOIUrl":"https://doi.org/10.1007/s12018-019-09263-1","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"17 1","pages":"109 - 122"},"PeriodicalIF":1.8,"publicationDate":"2019-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09263-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41854809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-15DOI: 10.1007/s12018-019-09262-2
N. Hong, Y. Rhee
{"title":"Comparison of Efficacy of Pharmacologic Treatments in Pregnancy- and Lactation-Associated Osteoporosis","authors":"N. Hong, Y. Rhee","doi":"10.1007/s12018-019-09262-2","DOIUrl":"https://doi.org/10.1007/s12018-019-09262-2","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"1 1","pages":"1-8"},"PeriodicalIF":1.8,"publicationDate":"2019-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09262-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42494136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01DOI: 10.1007/s12018-019-09265-z
M. Trbovich, Denny Mack, J. Bruder
{"title":"Osteoporosis in Veterans with Spinal Cord Injury: an Overview of Pathophysiology, Diagnosis, and Treatments","authors":"M. Trbovich, Denny Mack, J. Bruder","doi":"10.1007/s12018-019-09265-z","DOIUrl":"https://doi.org/10.1007/s12018-019-09265-z","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"17 1","pages":"108 - 94"},"PeriodicalIF":1.8,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09265-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41486040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01DOI: 10.1007/s12018-019-09261-3
M. Rothman, Sean J. Iwamoto
{"title":"Bone Health in the Transgender Population","authors":"M. Rothman, Sean J. Iwamoto","doi":"10.1007/s12018-019-09261-3","DOIUrl":"https://doi.org/10.1007/s12018-019-09261-3","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"17 1","pages":"77 - 85"},"PeriodicalIF":1.8,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09261-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45249378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01Epub Date: 2019-04-15DOI: 10.1007/s12018-019-09260-4
Pouneh K Fazeli
Anorexia nervosa, a psychiatric disease predominantly affecting women, is characterized by self- induced starvation and a resultant low-weight state. During starvation, a number of hormonal adaptations - including hypothalamic amenorrhea and growth hormone resistance - allow for decreased energy expenditure during periods of decreased nutrient intake, but these very same adaptations also contribute to the medical complications associated with chronic starvation, including low bone mass. Almost 90% of women with anorexia nervosa have bone mineral density (BMD) values more than one-standard deviation below the mean of healthy women at peak bone mineral density and this disease is associated with a significantly increased risk of fracture. Although multiple therapies have been studied for the treatment of low bone mass in anorexia nervosa, there are currently no approved therapies and few promising long-term therapeutic options. This review will outline the mediators of low bone mass in anorexia nervosa, discuss therapies that have been studied for the treatment of low BMD in this disorder, and highlight the important challenges that remain, including the differences in bone modeling in adolescents with anorexia nervosa as compared to adults, necessitating that potential therapies be tested in these two populations separately, and the paucity of long-term therapeutic strategies for treating bone loss in this disorder.
{"title":"Low bone mineral density in anorexia nervosa: Treatments and challenges.","authors":"Pouneh K Fazeli","doi":"10.1007/s12018-019-09260-4","DOIUrl":"https://doi.org/10.1007/s12018-019-09260-4","url":null,"abstract":"<p><p>Anorexia nervosa, a psychiatric disease predominantly affecting women, is characterized by self- induced starvation and a resultant low-weight state. During starvation, a number of hormonal adaptations - including hypothalamic amenorrhea and growth hormone resistance - allow for decreased energy expenditure during periods of decreased nutrient intake, but these very same adaptations also contribute to the medical complications associated with chronic starvation, including low bone mass. Almost 90% of women with anorexia nervosa have bone mineral density (BMD) values more than one-standard deviation below the mean of healthy women at peak bone mineral density and this disease is associated with a significantly increased risk of fracture. Although multiple therapies have been studied for the treatment of low bone mass in anorexia nervosa, there are currently no approved therapies and few promising long-term therapeutic options. This review will outline the mediators of low bone mass in anorexia nervosa, discuss therapies that have been studied for the treatment of low BMD in this disorder, and highlight the important challenges that remain, including the differences in bone modeling in adolescents with anorexia nervosa as compared to adults, necessitating that potential therapies be tested in these two populations separately, and the paucity of long-term therapeutic strategies for treating bone loss in this disorder.</p>","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":"17 2","pages":"65-76"},"PeriodicalIF":1.8,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09260-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37544069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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