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A Rare Case of Bilateral Spaghetti Injuries in Children due to Assault by Mother and Analysis of Functional Outcome at Three Years. 母亲袭击导致儿童双侧意面损伤的罕见病例及三年后的功能结果分析。
IF 0.3 Q4 SURGERY Pub Date : 2021-09-20 eCollection Date: 2023-06-01 DOI: 10.1055/s-0041-1735346
Parag B Lad, N Venkateshwaran, M R Thatte, Sanket Tanpure

Management of child abuse with flexor tendons, neurovascular injuries, and life-threatening conditions is challenging. It needs a multisectoral coordinated and synchronized team effort for successful outcomes. We present a case series of children abused by a parent with a sharp object. The children sustained multiple flexor tendon injuries, neurovascular injuries in upper limbs, and tracheal injury compromising respiration. We performed a tracheostomy to save a child and subsequently repaired numerous flexor tendons, nerves, and arteries. During follow-up, these children required secondary reconstruction (tenolysis, tendon lengthening, nerve reconstruction) for flexor contractures, stiffness, and sensory loss in distal forearms. We measured the range of movements and assessed the children's functional outcome using the Strickland score at 3-year follow-up. The range of movement and functional outcome was excellent in both children in our series. A timely performance of surgery, aided with efficient intensive care, therapy, and consistent posttraumatic psychosocial rehabilitation, produced excellent results in our series.

处理虐待儿童造成的屈肌腱、神经血管损伤和危及生命的情况极具挑战性。它需要多部门协调和同步的团队努力才能取得成功。我们介绍了一个被父母用锐器虐待的儿童病例系列。患儿多处屈肌腱损伤,上肢神经血管损伤,气管损伤影响呼吸。我们进行了气管造口术以挽救一名儿童,随后修复了多处屈肌腱、神经和动脉。在随访期间,这些患儿因前臂远端屈肌挛缩、僵硬和感觉缺失而需要二次重建(腱溶解、肌腱延长、神经重建)。我们测量了患儿的活动范围,并在三年随访时使用斯特里克兰评分法评估了患儿的功能效果。在我们的系列研究中,两名患儿的活动范围和功能效果都非常好。及时进行手术,并辅以有效的重症监护、治疗和持续的创伤后社会心理康复,使我们的系列手术取得了很好的效果。
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引用次数: 0
Head and Neck Reconstruction in Patients with Polycythemia Vera: Case Series and Literature Review. 多发性红细胞瘤患者的头颈部重建:病例系列和文献综述。
IF 0.3 Q4 SURGERY Pub Date : 2021-09-15 eCollection Date: 2023-02-01 DOI: 10.1055/s-0041-1734398
Sophia Dang, Leila J Mady, Rahilla Tarfa, Jonathan C Li, Frank Bontempo, Irina Chibisov, Mark W Kubik, Mario G Solari, Shaum Sridharan

Background  Polycythemia vera (PV) is a myeloproliferative disease with overproduction of erythrocytes, leukocytes, and platelets causing an increased risk of both thrombosis and hemorrhage. There are limited reports and no established guidelines for managing such patients undergoing reconstructive surgery. Methods  We present four patients with PV and head and neck cancer who required reconstruction after resection and provide a review of the current literature. Results  Preoperatively, patients on cytoreductive therapy continued with their treatment throughout their hospital course and had hematologic parameters normalized with phlebotomy or transfusions if needed. Two patients who underwent free flap surgery (cases 1 and 2) had postoperative courses complicated by hematoma formation and persistent anemia, requiring multiple transfusions. Cases 3 and 4 (JAK2+ PV and JAK2- PV, respectively) underwent locoregional flap without postoperative complications. Conclusion  Concomitant presentation of PV and head and neck cancer is uncommon and presents unique challenges for the reconstructive surgeon. Overall, we recommend that patients should have hematologic parameters optimized prior to surgery, continue ruxolitinib or hydroxyurea, and hold antiplatelet/anticoagulation per established department protocols. It is essential to engage a multidisciplinary team involving hematology, head and neck and reconstructive surgery, anesthesia, and critical care to develop a standardized approach for managing this unique subset of patients.

背景 多发性红细胞增多症(PV)是一种骨髓增生性疾病,红细胞、白细胞和血小板过度生成,导致血栓形成和出血的风险增加。目前关于此类患者接受整形手术的报道有限,也没有既定的管理指南。方法 我们介绍了四例在切除手术后需要进行重建的上皮细胞癌和头颈部癌症患者,并对目前的文献进行了回顾。结果 术前,接受细胞还原疗法的患者在整个住院期间继续接受治疗,并在必要时通过抽血或输血使血液指标恢复正常。两名接受游离皮瓣手术的患者(病例 1 和 2)术后因血肿形成和持续贫血而并发症,需要多次输血。病例 3 和 4(分别为 JAK2+ PV 和 JAK2- PV)接受了局部皮瓣手术,术后未出现并发症。结论 PV 和头颈部癌症并发的情况并不常见,给整形外科医生带来了独特的挑战。总之,我们建议患者在术前应优化血液学参数,继续服用鲁索利替尼或羟基脲,并按照既定的科室方案进行抗血小板/抗凝治疗。让血液学、头颈部和整形外科、麻醉和重症监护等多学科团队参与进来,制定管理这一特殊患者的标准化方法至关重要。
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引用次数: 0
Validation of a Handprint for Clinical Evaluation of Dupuytren's Contracture. 验证用于杜普伊特伦挛缩症临床评估的手印。
IF 0.3 Q4 SURGERY Pub Date : 2021-08-25 eCollection Date: 2023-06-01 DOI: 10.1055/s-0041-1735347
Takashi Ajiki, Akira Murayama, Yukinori Hayashi, Katsushi Takeshita

Objective  We have developed a handprint-based method for visualizing and quantifying the palmar contact of patients with Dupuytren's contracture. The purpose of this study was to examine whether the generated handprint was useful for assessing the severity of flexion contracture of the fingers and for evaluating the therapeutic effects of collagenase clostridium histolyticum (CCH) injection for Dupuytren's contracture. Methods  The handprint was created by applying medical-grade ethanol-containing hand sanitizer over the entire palmar surface of the affected hand and then pressing it on thermal paper for word processors. The reliability of the handprint was evaluated through test-retest of 10 healthy volunteers at an interval of 10 days, and the validity of the handprint was assessed using a flexion contracture model in which the little finger was fixed in an Alfence splint. In addition, we obtained handprints of the affected hand in 33 patients with unilateral Dupuytren's contracture both before CCH injection and at the final observation after injection to investigate the contact area of the hand (CAH) and the length of the hand (LH). The relationships between CAH, LH, total extension deficit angle (TEDA), and patient-reported outcome measures (Japanese Society for Surgery of the Hand Version of the Quick Disability of Arm, Shoulder, and Hand Questionnaire [Quick DASH-JSSH] and Hand20) were examined. Results  The test-retest correlation coefficient was 0.9187 ( p  < 0.001) for CAH and 0.9052 ( p  < 0.001) for LH, indicating high reliability of the handprint. The ratios of CAH and LH decreased gradually as the contracture angle of the splinted finger increased. The handprint revealed a marked improvement of palmar contact after CCH injection for Dupuytren's contracture. Furthermore, the ratios of CAH and LH were strongly correlated with TEDA, Quick DASH-JSSH, and Hand20 before treatment. Conclusion  Our handprint-based assessment method was extremely useful for clinical evaluation of CCH treatment for Dupuytren's contracture. Type of Study/Level of Evidence  Therapeutic.

目的 我们开发了一种基于手印的方法,用于观察和量化杜普伊特伦挛缩症患者的手掌接触情况。本研究的目的是检验生成的手印是否有助于评估手指屈曲挛缩的严重程度,以及评估胶原酶溶解梭菌(CCH)注射治疗杜普伊特伦挛缩症的疗效。方法 将医用乙醇洗手液涂抹在患手的整个掌面,然后将其按压在文字处理机的热敏纸上,以此制作手印。我们对 10 名健康志愿者进行了间隔 10 天的重测,评估了手印的可靠性,并使用屈曲挛缩模型评估了手印的有效性,在该模型中,小指被固定在 Alfence 夹板中。此外,我们还采集了 33 名单侧杜普伊特伦挛缩症患者在注射 CCH 前和注射后最后观察期间的患手手纹,以研究手的接触面积(CAH)和手的长度(LH)。研究了CAH、LH、总伸展缺损角(TEDA)和患者报告的结果指标(日本手外科学会快速手臂、肩部和手部残疾问卷[Quick DASH-JSSH]和Hand20)之间的关系。结果 测试-重复相关系数为 0.9187 ( p p 结论 我们基于手印的评估方法对于杜普伊特伦挛缩症的 CCH 治疗的临床评估非常有用。研究类型/证据级别 治疗。
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引用次数: 0
Correlation of the I-HaND Scale with Other Musculoskeletal Patient-Reported Outcome Measurement Scores. I-HaND 量表与其他肌肉骨骼患者报告结果测量评分的相关性。
IF 0.3 Q4 SURGERY Pub Date : 2021-08-25 eCollection Date: 2023-06-01 DOI: 10.1055/s-0041-1735348
Joost T P Kortlever, S Ryan Pierson, David Ring, Lee M Reichel, Gregg A Vagner

Background  Experiments can determine if nerve-specific patient-reported outcome measures (PROMs) can outperform regional or condition-specific PROMs. We compared a nerve-specific PROM of the upper extremity, the Impact of Hand Nerve Disorders (I-HaND) scale, to other validated measures quantifying activity intolerance and sought to assess interquestionnaire correlations and factors independently associated with activity intolerance and pain intensity. Methods  One hundred and thirty patients with any upper extremity nerve-related condition completed measures of demographics, psychological limitations, quality of life, activity intolerance, and pain intensity. To quantify activity intolerance, we used the I-HaND, Patient-Reported Outcomes Measurement Information System Physical Function Upper Extremity, and Disabilities of the Arm, Shoulder and Hand short form. Results  Strong interquestionnaire correlations were found between the activity intolerance measures ( r between 0.70 and 0.91). Multivariable analysis revealed that greater activity intolerance and greater pain intensity correlated most with greater symptoms of depression on all scales, with symptoms of depression accounting for 53 to 84% of the variability in the PROMs. Conclusion  There is no clear advantage of the nerve-specific I-HaND over shorter, regional PROMs, perhaps because they are all so closely tied to mental health. Unless an advantage relating to responsiveness to treatment is demonstrated, we support using a brief arm-specific PROM for all upper extremity conditions. Level of Evidence  Level II; Prognostic.

背景 实验可以确定神经特异性患者报告结果测量(PROM)是否优于区域性或病情特异性 PROM。我们将上肢神经特异性 PROM--手部神经紊乱影响(I-HaND)量表与其他量化活动不耐受性的有效测量方法进行了比较,并试图评估问卷间的相关性以及与活动不耐受性和疼痛强度独立相关的因素。方法 130 名患有任何上肢神经相关疾病的患者完成了对人口统计学、心理限制、生活质量、活动不耐受性和疼痛强度的测量。为了量化活动不耐受性,我们使用了 I-HaND、患者报告结果测量信息系统上肢物理功能以及手臂、肩部和手部残疾简表。结果 各项活动不耐受测量指标之间存在很强的问卷间相关性(r 在 0.70 和 0.91 之间)。多变量分析表明,在所有量表中,活动不耐受性越强和疼痛强度越大与抑郁症状越严重的相关性最大,抑郁症状占 PROMs 变异的 53% 至 84%。结论 与较短的区域性 PROM 相比,神经特异性 I-HaND 没有明显的优势,这可能是因为它们都与心理健康密切相关。除非在治疗反应性方面显示出优势,否则我们支持在所有上肢疾病中使用简短的手臂特异性 PROM。证据级别 II;预后性。
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引用次数: 0
Mini TightRope Suspension Allows for Accelerated Rehabilitation following Ligament Reconstruction Interposition Arthroplasty of the Basal Joint of the Thumb. 迷你 TightRope 悬挂系统可加快拇指基关节韧带重建置换术后的康复。
IF 0.3 Q4 SURGERY Pub Date : 2021-08-03 eCollection Date: 2023-04-01 DOI: 10.1055/s-0041-1730887
Rasmus Wejnold Jørgensen, Kiran Annette Anderson, Claus Hjorth Jensen

Introduction  Surgical treatment of thumb trapeziometacarpal osteoarthritis usually involves 4 to 8 weeks of postoperative casting and splinting followed by varying mobilization protocols. Suspension arthroplasty has been described as an alternative to allow earlier range of motion exercises. The purpose of this study was to compare patient-reported outcomes (PRO) when adding a two-string suture-button suspension arthroplasty (Mini TightRope, MTR) to our usual procedure of ligament reconstruction and tendon interposition (LRTI), allowing early mobilization. Can we allow early mobilization using this technique without jeopardizing the PRO results at the 1 year follow-up and without an increased risk of complication? Materials and Methods  A prospective study using the MTR system (Arthrex) as a suture-button suspensionplasty was conducted. Twelve patients (MTR group) and 36 historical patients (LRTI alone) were included. Results  At 12 months, the median value for quick disabilities of the arm, shoulder, and hand was 11.3 (range, 0-43.2) in the MTR group and 13.6 (range, 0-88.6) in the LRTI group, resulting in similar improvements, p  = 0.46. One in twelve patients in the MTR group was dissatisfied and 9 in 36 in the LRTI group were dissatisfied, p  = 0.41. No complications were observed during the first year. Conclusion  Supplemental suture-button suspensionplasty can be utilized for high demand patients and patients who want to reduce immobilization time without major complications and with similar PRO as LRTI at 6 and 12 months. Level of evidence  Four case series.

导言:拇指掌骨骨关节炎的手术治疗通常需要 4 到 8 周的术后石膏和夹板固定,然后再进行不同的活动方案。悬吊式关节置换术被认为是一种可提前进行活动范围锻炼的替代方法。本研究的目的是比较患者报告的结果(PRO),即在韧带重建和肌腱间置术(LRTI)的基础上增加双线缝合扣悬吊关节置换术(Mini TightRope,MTR),并允许早期活动。我们能否在不影响 1 年随访的 PRO 结果和不增加并发症风险的情况下,使用这种技术允许早期活动?材料与方法 采用 MTR 系统(Arthrex)作为缝合扣悬吊成形术进行了一项前瞻性研究。共纳入了 12 名患者(MTR 组)和 36 名历史患者(单纯 LRTI)。结果 12个月后,MTR组的手臂、肩部和手部快速残疾中位值为11.3(范围0-43.2),LRTI组为13.6(范围0-88.6),改善程度相似,P = 0.46。MTR 组每 12 名患者中有 1 人不满意,LRTI 组每 36 名患者中有 9 人不满意,P = 0.41。第一年内未发现并发症。结论 补充缝合扣悬吊成形术可用于需求量大的患者和希望缩短固定时间的患者,且不会出现重大并发症,6 个月和 12 个月后的结果与 LRTI 相似。证据级别 四个病例系列。
{"title":"Mini TightRope Suspension Allows for Accelerated Rehabilitation following Ligament Reconstruction Interposition Arthroplasty of the Basal Joint of the Thumb.","authors":"Rasmus Wejnold Jørgensen, Kiran Annette Anderson, Claus Hjorth Jensen","doi":"10.1055/s-0041-1730887","DOIUrl":"10.1055/s-0041-1730887","url":null,"abstract":"<p><p><b>Introduction</b>  Surgical treatment of thumb trapeziometacarpal osteoarthritis usually involves 4 to 8 weeks of postoperative casting and splinting followed by varying mobilization protocols. Suspension arthroplasty has been described as an alternative to allow earlier range of motion exercises. The purpose of this study was to compare patient-reported outcomes (PRO) when adding a two-string suture-button suspension arthroplasty (Mini TightRope, MTR) to our usual procedure of ligament reconstruction and tendon interposition (LRTI), allowing early mobilization. Can we allow early mobilization using this technique without jeopardizing the PRO results at the 1 year follow-up and without an increased risk of complication? <b>Materials and Methods</b>  A prospective study using the MTR system (Arthrex) as a suture-button suspensionplasty was conducted. Twelve patients (MTR group) and 36 historical patients (LRTI alone) were included. <b>Results</b>  At 12 months, the median value for quick disabilities of the arm, shoulder, and hand was 11.3 (range, 0-43.2) in the MTR group and 13.6 (range, 0-88.6) in the LRTI group, resulting in similar improvements, <i>p</i>  = 0.46. One in twelve patients in the MTR group was dissatisfied and 9 in 36 in the LRTI group were dissatisfied, <i>p</i>  = 0.41. No complications were observed during the first year. <b>Conclusion</b>  Supplemental suture-button suspensionplasty can be utilized for high demand patients and patients who want to reduce immobilization time without major complications and with similar PRO as LRTI at 6 and 12 months. <b>Level of evidence</b>  Four case series.</p>","PeriodicalId":45368,"journal":{"name":"Journal of Hand and Microsurgery","volume":"15 2","pages":"141-147"},"PeriodicalIF":0.3,"publicationDate":"2021-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070004/pdf/10-1055-s-0041-1730887.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9299927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Free Vascularized Joint Transfer from Toes for Finger Reconstruction in a 2-Year-Old Child with Good Functional Recovery. 为一名两岁儿童从脚趾进行游离血管化关节转移以重建手指,患者功能恢复良好。
IF 0.3 Q4 SURGERY Pub Date : 2021-08-03 eCollection Date: 2023-04-01 DOI: 10.1055/s-0041-1732807
Jyoshid R Balan

A 2-year-old male child sustained injury to middle and ring fingers of the right hand following a road traffic accident. He had mutilated fingers with loss of middle phalanx along with proximal interphalangeal (PIP) joint, distal interphalangeal joint of middle finger, and loss of part of middle phalanx and PIP joint of the ring finger. There was dorsal tissue loss of both the fingers. With staged reconstructive strategy, we could salvage the fingers. In the initial part, the soft tissue reconstruction was done using pedicled groin flap. In the later stage, free PIP joint transfer from the second toes of both feet was used to reconstruct the bone and PIP joint of the ring and middle finger. A year following the joint transfer, the child had good functional outcome.

一名两岁男童在一次道路交通事故中右手中指和无名指受伤。他的手指残缺不全,中指的中指骨和近端指间关节(PIP)缺失,中指的远端指间关节缺失,无名指的部分中指骨和 PIP 关节缺失。两个手指的指背组织缺失。通过分期重建策略,我们保住了手指。在初期,我们使用带蒂腹股沟皮瓣进行软组织重建。后期,我们从双脚第二趾游离转移 PIP 关节,重建无名指和中指的骨和 PIP 关节。关节转移术后一年,患儿的功能恢复良好。
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引用次数: 0
Reconstruction of a Composite Defect of the Distal Index Finger Using a Chimeric Reverse Flow Second Dorsal Metacarpal Artery Flap: A Case Report. 使用嵌合反向流第二掌背动脉皮瓣重建食指远端复合缺损:病例报告。
IF 0.3 Q4 SURGERY Pub Date : 2021-07-15 eCollection Date: 2023-04-01 DOI: 10.1055/s-0041-1731938
Koichi Yano, Yasunori Kaneshiro, Megumi Ishiko, Seungho Hyun, Hideki Sakanaka

The reconstruction for mild tissue loss at the distal part of a finger is challenging. We report about a 29-year-old man presenting with traumatic tissue loss at the distal interphalangeal (DIP) joint of the index finger, including skin, bone, and nerve. Reconstruction using two types of flaps was performed. The dorsal skin flap, nourished by the second dorsal metacarpal artery (SDMA) perforator, was elevated. The vascularized second metacarpal bone, nourished by the SDMA, was also elevated. Using the vascular connection between the DMA and the palmar digital artery (PDA), both flaps were raised to the distal part of the finger, and the pivot point was set at the dorsal proximal phalanx. After arthrodesis of the DIP joint with the vascularized second metacarpal bone, the digital nerve was repaired using the cutaneous nerve in the skin flap, and the skin defect was covered using the perforator flap. The postoperative course, including flap survival and bone union, was uneventful. A good indication for the reconstruction of the distal part of a finger with this technique is when the defect sizes of the skin and bone differ and the vascular connection between the SDMA and dorsal branch of PDA is not injured.

手指远端轻度组织缺损的重建具有挑战性。我们报告了一名 29 岁男性的食指远端指间关节(DIP)创伤性组织缺损情况,包括皮肤、骨骼和神经。我们使用两种皮瓣进行了重建。由第二掌背动脉(SDMA)穿孔器滋养的背侧皮瓣被隆起。由第二掌骨背动脉(SDMA)穿孔器滋养的血管化第二掌骨也被隆起。利用 DMA 和掌侧数字动脉 (PDA) 之间的血管连接,将两个皮瓣提升至手指远端,并将支点设置在背侧近节指骨处。在用血管化的第二掌骨固定 DIP 关节后,用皮瓣中的皮神经修复了数字神经,并用穿孔器皮瓣覆盖了皮肤缺损。包括皮瓣存活和骨结合在内的术后过程都很顺利。当皮肤和骨骼的缺损大小不一,且 SDMA 和 PDA 背侧支之间的血管连接未受到损伤时,采用该技术重建手指远端是一个很好的适应症。
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引用次数: 0
Deltopectoral Approach Overcomes All Blind Spots for Axillary Nerve Transfers in Brachial Plexus Injuries and Isolated Axillary Nerve Injuries. 胸骨下入路克服了臂丛神经损伤和孤立性腋窝神经损伤中腋窝神经转移的所有盲点。
IF 0.3 Q4 SURGERY Pub Date : 2021-07-01 Epub Date: 2021-07-07 DOI: 10.1055/s-0041-1732769
J Terrence Jose Jerome
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引用次数: 0
Can Open Hand Injuries Wait for Their Surgery in a Tertiary Hospital? 手部开放性损伤可以在三级医院等待手术吗?
IF 0.3 Q4 SURGERY Pub Date : 2021-07-01 Epub Date: 2021-03-04 DOI: 10.1055/s-0041-1725220
Wei Ping Sim, Hannah Jia Hui Ng, Benjamin Zhiren Liang, Vaikunthan Rajaratnam

Objective  Open hand injuries are routinely admitted and planned for surgery acutely, competing with other surgical emergencies. This retrospective study aims to evaluate if a delay in timing to surgery for open hand injuries led to an increased rate of infection. Materials and Methods  All patients who sustained open hand injuries and underwent semi-emergent day surgery from January 1, 2015 to December 31, 2016 were included. Outcome of postoperative infection was analyzed against demographic data, injury details, and delay from trauma to therapy. Results  There were 232 cases (91% males) included, with 92.0% performed under local anesthesia. Deep seated postoperative infection was seen in 1.3%, which was not significantly associated with delay to surgery. Conclusion  We had comparable infection rates as compared with published literature. Delayed timing of surgical treatment in open hand injuries was not associated with increased rates of deep-seated infection. Managing open hand injuries as semi-emergent surgeries may be acceptable given the low infection rates.

目标 开放性手部损伤通常会被紧急收治并计划手术,与其他外科急症形成竞争。本回顾性研究旨在评估开放性手外伤手术时机的延迟是否会导致感染率增加。材料和方法 纳入 2015 年 1 月 1 日至 2016 年 12 月 31 日期间所有手部开放性损伤并接受半急诊日间手术的患者。根据人口统计学数据、损伤细节和从创伤到治疗的延迟时间分析术后感染的结果。结果 共纳入 232 例病例(91% 为男性),92.0% 在局部麻醉下进行。术后深部感染占 1.3%,与手术延迟无明显关系。结论 与已发表的文献相比,我们的感染率相当。手部开放性损伤手术治疗时间的延迟与深部感染率的增加无关。鉴于感染率较低,将手部开放性损伤作为半紧急手术来处理可能是可以接受的。
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引用次数: 0
Early Suspicion of Heparin-Induced Thrombocytopenia for Successful Free Flap Salvage: Reports of Two Cases. 早期怀疑肝素诱发的血小板减少症以成功挽救游离皮瓣:两个病例的报告。
IF 0.3 Q4 SURGERY Pub Date : 2021-07-01 Epub Date: 2020-06-30 DOI: 10.1055/s-0040-1713692
Turan Mehdizade, Osman Kelahmetoglu, Volkan Gurkan, Güven Çetin, Ethem Guneren

Heparin-induced thrombocytopenia (HIT) is an underestimated complication of heparin treatment. Flap loss and related morbidity (even mortality) are caused by occlusion of the capillary vessels by a highly immunogenic complex formed by adherence of antiheparin antibodies to platelet factor 4. Early suspicion and effective treatment of HIT developing in two free flaps are described. We report on the management of two patients with HIT. Both patients were treated successfully by early suspicion and hematology consultation. Heparin products were discontinued; the patients were switched to a nonheparin anticoagulant. We emphasize the importance of early diagnosis, hematologist assessment, and a change to a nonheparin anticoagulant to prevent flap failure and possibly the catastrophic consequences of such failure.

肝素诱导的血小板减少症(HIT)是肝素治疗的一种被低估的并发症。抗肝素抗体附着在血小板因子 4 上形成的高免疫原性复合物堵塞了毛细血管,导致皮瓣脱落和相关发病率(甚至死亡率)。本文介绍了对在两个游离皮瓣中发生的 HIT 的早期怀疑和有效治疗。我们报告了两名 HIT 患者的治疗情况。通过早期怀疑和血液科会诊,两名患者都得到了成功治疗。肝素产品被停用;患者转用了非肝素抗凝剂。我们强调了早期诊断、血液科医生评估和改用非肝素抗凝剂的重要性,以防止瓣膜功能衰竭和可能出现的灾难性后果。
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引用次数: 0
期刊
Journal of Hand and Microsurgery
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