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Early Prenatal Detection of Recessive Split-hand/Foot Malformation Caused by a Homozygous Variant of WNT10B. 产前早期检测到由 WNT10B 同源变体引起的隐性手足分裂畸形
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-28 eCollection Date: 2024-07-01 DOI: 10.4103/jmu.jmu_147_23
Gui-Lan Chen, Li Zhen, Dong-Zhi Li
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引用次数: 0
Impact of Adding Urethral Sonography with Retrograde Urethrography in Preoperative Assessment of Anterior Urethral Stricture. 在术前评估前尿道狭窄时增加尿道超声和逆行尿道造影的影响
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-28 eCollection Date: 2024-07-01 DOI: 10.4103/jmu.jmu_4_23
Nidhi Sehgal, Vinod Priyadarshi

Background: Even with underlying risk factors and limitations, retrograde urethrography (RGU) is the most popular imaging modality in the assessment of anterior urethral stricture. Urethral sonography (SUG) is an able imaging modality in use for the last few years which evaluates anterior urethral stricture without these risks, though it is still not much popular due to its complexity. This prospective study was designed to compare the assessment made on SUG with the results of RGU and to analyze its impact on surgical decision-making when the results of SUG were taken into consideration with RGU.

Methods: Thirty patients with anterior urethral stricture were assessed for stricture location, length, and associated urethral pathologies with RGU and surgery planned accordingly. Later, all were reevaluated with SUG, results compared with that of RGU and surgery replanned, considering both RGU and SUG findings. All results were compared with operative findings.

Results: The mean stricture lengths on SUG, RGU, and surgery were 20.45 mm, 17.15 mm, and 20.38 mm, respectively. Overall sensitivity and specificity of SUG in actual stricture length prediction were 92.3% and 96.1%, whereas these were 78.9% and 85.1%, respectively, on RGU. Spongiofibrosis was assessed only with SUG, that too, with 85%-90% accuracy. Surgical plan was changed in 31% of cases when SUG findings were taken into account along with RGU findings.

Conclusion: SUG was found more precise modality in the measurement of stricture length and more informative and elaborative in providing added knowledge of degree of spongiofibrosis and associated pathologies of diseased urethra and periurethral tissue. For better preoperative planning of anterior urethral strictures, SUG should be added to work-up along with RGU.

背景:即使存在潜在的风险因素和局限性,逆行尿道造影术(RGU)仍是评估前尿道狭窄最常用的成像方式。尿道声学造影(SUG)是近几年开始使用的一种有效的成像方式,它可以评估前尿道狭窄而不存在这些风险,但由于其复杂性,目前仍不太流行。这项前瞻性研究旨在比较 SUG 与 RGU 的评估结果,并分析 SUG 与 RGU 的评估结果对手术决策的影响:方法: 用 RGU 评估了 30 名前尿道狭窄患者的狭窄位置、长度和相关尿道病变,并制定了相应的手术计划。之后,所有患者都接受了 SUG 重新评估,将结果与 RGU 的结果进行比较,并考虑 RGU 和 SUG 的结果重新制定手术计划。所有结果均与手术结果进行了比较:SUG、RGU 和手术的平均狭窄长度分别为 20.45 毫米、17.15 毫米和 20.38 毫米。SUG 对实际狭窄长度预测的总体敏感性和特异性分别为 92.3% 和 96.1%,而 RGU 的敏感性和特异性分别为 78.9% 和 85.1%。海绵状纤维化仅通过 SUG 进行评估,准确率为 85%-90%。在考虑 SUG 和 RGU 结果的情况下,31% 的病例改变了手术方案:结论:SUG 被认为是测量狭窄长度更精确的方法,在提供更多关于海绵体纤维化程度以及病变尿道和尿道周围组织的相关病理知识方面更具信息性和详细性。为了更好地制定前尿道狭窄的术前计划,SUG 应与 RGU 一起加入术前检查。
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引用次数: 0
CME Test. CME 测试。
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-28 eCollection Date: 2024-07-01
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引用次数: 0
Multimodality Imaging for Rare Presentation of Placenta Increta in the First Trimester in a Patient with Previous Cesarean Section and Asherman Syndrome. 多模态成像治疗曾行剖宫产术和阿舍曼综合征患者妊娠头三个月胎盘内陷的罕见病例。
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-28 eCollection Date: 2024-07-01 DOI: 10.4103/jmu.jmu_33_23
Harshna V Vadvala, Jonathan E Henning, Abimbola Aina-Mumuney

We report multi-modality imaging (Ultrasound and Magnetic Resonance Imaging) findings of a rare complication in a multi-gravida patient with history of Asherman syndrome presenting with placenta increta in a cesarean scar ectopic pregnancy. The appropriate diagnosis was established with imaging and patient was managed surgically with total abdominal hysterectomy and bilateral salpingectomy. Asherman syndrome and its management of hysteroscopic adhesiolysis are associated with increased odds of placenta accreta spectrum and postpartum hemorrhage. Patients with Asherman syndrome are considered high risk in pregnancy and should be closely monitored for placental site abnormalities during current and subsequent pregnancies.

我们报告了一名多胎妊娠患者的多模态成像(超声波和磁共振成像)结果,该患者有阿什曼综合征病史,在剖宫产瘢痕异位妊娠中出现胎盘增大,是一种罕见的并发症。通过造影确定了适当的诊断,并通过全腹子宫切除术和双侧输卵管切除术对患者进行了手术治疗。阿瑟曼综合征及其宫腔镜粘连溶解术与胎盘早剥和产后出血的几率增加有关。阿什曼综合征患者被视为妊娠高危人群,在本次妊娠和以后的妊娠中应密切监测胎盘部位是否异常。
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引用次数: 0
Prenatal Ultrasound and Magnetic Resonance Findings of Glutaric Acidemia Type 1 and Its Challenges in Prenatal Diagnosis. 1 型戊二酸血症的产前超声波和磁共振检查结果及其产前诊断中的挑战。
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-28 eCollection Date: 2024-07-01 DOI: 10.4103/jmu.jmu_63_24
Jo-Ting Wang, Han-Jui Lee, Tung-Yao Chang

Glutaric acidemia type 1 (GA1) presents unique challenges in prenatal diagnosis, especially in cases with no family history. This review article aims to review and present the prenatal ultrasound and magnetic resonance findings of GA1 and consolidate key insights into the difficulties associated with GA1 prenatal diagnosis and the neuroimaging features that require careful differentiation during the diagnostic process.

戊二酸血症 1 型(GA1)给产前诊断带来了独特的挑战,尤其是在无家族史的病例中。这篇综述文章旨在回顾和介绍 GA1 的产前超声和磁共振检查结果,并对与 GA1 产前诊断相关的困难以及诊断过程中需要仔细鉴别的神经影像学特征进行深入分析。
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引用次数: 0
Dissimilar Planes and Approaches with Common Neural Targets - A Cadaveric Evaluation of Three Different Ultrasound-guided Fascial Plane Blocks for Lumbar Plexus Nerves. 相同神经靶点的不同平面和方法--对三种不同超声引导下筋膜平面阻滞治疗腰丛神经的尸体评估。
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-28 eCollection Date: 2024-07-01 DOI: 10.4103/jmu.jmu_70_23
Sandeep Diwan, Georg Feigl, S Shivaprakash, Archana Areti

Background: The lumbar plexus (LP) is a group of nerves located at the fourth lumbar vertebra level, between the anterior two-thirds and posterior one-thirds of the psoas muscle. In this study, the researchers aimed to investigate the spread of latex in injections of LP, suprainguinal fascia iliaca, and circum-psoas planes to assess the different regional techniques for blocking LP nerves (LPNs).

Methods: The study involved performing ultrasound-guided injections of three different colored latexes in six cadavers. The researchers observed and compared the spread of latex in each plane by taking cross sections at the levels of L4, anterior superior iliac spine (ASIS), and sacral foramina (SF). The spread of latex and LPN staining was documented and analyzed through photography.

Results: The results showed that the latex spread within the psoas muscle and fascia iliaca plane (FIP) during LP injections, whereas suprainguinal fascia iliaca injections showed latex dissemination in the FIP at both ASIS and SF levels. On the other hand, circum-psoas injections spread beneath the iliopsoas fascia at both levels and medially toward the external iliac vessels. Despite this spread, there was no communication between the three planes, and there was no mixing of latex from the different injections at any level.

Conclusion: There are distinct fascial planes, for the three approaches, with no communication between them. While latex diffused from LP plane to FIP, no mixing of dye was observed and also the reverse could not be achieved. These findings suggest that different regional techniques for blocking LPNs have their unique planes of action.

背景:腰丛(LP)是位于第四腰椎水平、腰肌前三分之二和后三分之一之间的一组神经。在这项研究中,研究人员旨在调查注射 LP、髂腹股沟上筋膜和腰大肌周围平面时乳胶的扩散情况,以评估阻断 LP 神经(LPN)的不同区域技术:研究包括在超声波引导下对六具尸体注射三种不同颜色的乳胶。研究人员通过在 L4、髂前上棘(ASIS)和骶骨孔(SF)水平拍摄横截面来观察和比较乳胶在每个平面的扩散情况。通过摄影记录和分析乳胶和 LPN 染色的扩散情况:结果表明,LP 注射时,乳胶在腰肌和髂筋膜平面(FIP)内扩散,而髂腹股沟上筋膜注射时,乳胶在 ASIS 和 SF 水平的 FIP 内扩散。另一方面,髂腰肌周围注射则在两个层面的髂腰肌筋膜下方和内侧向髂外血管扩散。尽管有这种扩散,但这三个平面之间没有沟通,而且在任何水平上,不同注射部位的乳胶都没有混合:结论:三种方法都有不同的筋膜平面,它们之间没有沟通。当乳胶从 LP 平面扩散到 FIP 时,没有观察到染料混合,也无法实现反向扩散。这些发现表明,阻断 LPN 的不同区域技术有其独特的作用平面。
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引用次数: 0
Ultrasound Assessment of Facial and Neck Aging: A Noninvasive Approach to a Minimally Invasive Treatment. 超声波评估面部和颈部老化:微创治疗的无创方法
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-28 eCollection Date: 2024-07-01 DOI: 10.4103/jmu.jmu_175_23
Hassan Nasreddine, Yehya Tlaiss, Firas Hassan, Reina Ibrahim

This technical note explores the diagnostic potential of ultrasound in assessing age-related changes in the soft tissues of the lower face and neck, with a primary focus on identifying causes of contour deformities and guiding minimally invasive rejuvenation procedures. Seventeen clinical patients with various age-related soft-tissue changes were subjected to ultrasound assessments, targeting issues such as soft-tissue sagging, supra- and subplatysmal adipose tissue excess, platysma thickness, and localization of ptotic platysma strands. The ultrasound examinations successfully identified specific anatomical features contributing to age-related soft-tissue changes in all 17 patients. This information guided tailored treatment plans, resulting in remarkable esthetic improvements in each case. The discussion emphasizes ultrasound's invaluable role as a diagnostic tool for precisely identifying soft-tissue alterations in the lower face and neck. The noninvasive nature and high spatial resolution of ultrasound make it particularly effective for this purpose. The corrective methods guided by ultrasound findings proved to be minimally invasive and yielded successful outcomes in all cases, promoting high levels of patient satisfaction. The study highlights the underutilization of ultrasound's diagnostic potential in clinical practice and highlights the importance of its incorporation into routine assessments. Ultrasound emerges as a cost-effective, noninvasive, and accessible means of accurately diagnosing age-related soft-tissue changes, empowering clinicians to tailor rejuvenation procedures to each patient's unique needs. The hope is that by emphasizing its utility, this study encourages the broader adoption of ultrasound in clinical practice.

本技术说明探讨了超声波在评估下面部和颈部软组织与年龄有关的变化方面的诊断潜力,主要侧重于确定轮廓畸形的原因和指导微创年轻化手术。我们对 17 位患有各种与年龄相关的软组织变化的临床患者进行了超声波评估,主要针对软组织下垂、板上和板下脂肪组织过多、板膜厚度和下垂板膜股的定位等问题。超声波检查成功确定了所有 17 名患者与年龄有关的软组织变化的具体解剖特征。这些信息为量身定制的治疗方案提供了指导,使每个病例的美学效果都得到了显著改善。讨论强调了超声波作为诊断工具在精确识别下面部和颈部软组织变化方面的宝贵作用。超声波的非侵入性和高空间分辨率使其在这方面尤为有效。事实证明,以超声波检查结果为指导的矫正方法是微创的,在所有病例中都取得了成功的结果,提高了患者的满意度。这项研究凸显了超声诊断在临床实践中的潜力未得到充分利用,并强调了将其纳入常规评估的重要性。超声波是准确诊断与年龄相关的软组织变化的一种经济、无创、便捷的方法,使临床医生有能力根据每位患者的独特需求定制年轻化手术。希望这项研究能通过强调超声波的实用性,鼓励在临床实践中更广泛地采用超声波。
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引用次数: 0
When the Baker's Cyst Slips and the Fascia Cruris Rips: A Story on Knee Ultrasound. 当贝克氏囊肿滑脱和筋膜撕裂时:膝关节超声的故事
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-07-12 eCollection Date: 2024-07-01 DOI: 10.4103/jmu.jmu_166_23
Ahmad Jasem Abdulsalam, Vincenzo Ricci, Levent Özçakar
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引用次数: 0
Associations of Increased Red Cell Distribution Width Levels with the Severity of Carotid Artery Stenosis: Cross-sectional Study Results. 红细胞分布宽度增加与颈动脉狭窄严重程度的关系:横断面研究结果。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-29 eCollection Date: 2024-04-01 DOI: 10.4103/jmu.jmu_46_23
Oleg Gaisenok

Background: Red blood cell distribution width (RDW) is being actively studied as a biomarker in various cardiovascular diseases (CVDs). The aim of this study was to conduct a comparative analysis of RDW in patients with carotid atherosclerosis, comparing it with an assessment of the severity of carotid artery stenosis (CAS).

Methods: The Duplex registry database was used to conduct this retrospective cross-sectional study. The study participants underwent a complete blood count test, analysis for lipid profile, and carotid ultrasound. The patients were divided into 5 groups depending on CAS degree: none; 20%-49%; 50%-69%; 70%-99%; and occlusion.

Results: Data from 2548 patients were included in the final analysis (mean age: 57.9 ± 12.3 years; 51% males [n = 1301]). The analysis confirmed the relationship between the increase in the RDW index and CAS gradation increase in men (Kr-W H = 16.43; P = 0.0009), but was not confirmed in women (Kr-W H = 4.32; P = 0.22). Significantly higher levels of high-density lipoprotein cholesterol and platelets and lower levels of red blood cell and white blood cells were registered in female patients without CAS and with CAS < 50% compared with men (P < 0.001).

Conclusion: The results of the present study showed that RDW is an indicator whose increase is associated with an increase in the degree of carotid atherosclerosis in men, but not in women. This allows to discuss the role of the RDW index as a possible new laboratory biomarker of inflammation and progression of atherosclerosis, which can make an additional contribution to the formation of increased morbidity and mortality in men from atherosclerotic CVD.

背景:红细胞分布宽度(RDW)作为各种心血管疾病(CVDs)的生物标志物正在被积极研究。本研究旨在对颈动脉粥样硬化患者的红细胞分布宽度进行比较分析,并将其与颈动脉狭窄(CAS)严重程度评估进行比较:这项回顾性横断面研究使用了 Duplex 登记数据库。研究参与者接受了全血细胞计数检查、血脂分析和颈动脉超声检查。根据 CAS 的程度将患者分为 5 组:无;20%-49%;50%-69%;70%-99%;闭塞:最终分析纳入了 2548 名患者的数据(平均年龄:57.9 ± 12.3 岁;51% 为男性 [n = 1301])。分析证实了男性 RDW 指数的增加与 CAS 分级增加之间的关系(Kr-W H = 16.43;P = 0.0009),但未证实女性 RDW 指数的增加与 CAS 分级增加之间的关系(Kr-W H = 4.32;P = 0.22)。与男性相比,未患 CAS 和 CAS < 50% 的女性患者的高密度脂蛋白胆固醇和血小板水平明显升高,红细胞和白细胞水平明显降低(P < 0.001):本研究结果表明,RDW 是一项指标,其增加与男性颈动脉粥样硬化程度的增加有关,但与女性无关。由此可以讨论 RDW 指数作为炎症和动脉粥样硬化进展的一种可能的新实验室生物标志物的作用,它可以为男性动脉粥样硬化性心血管疾病发病率和死亡率的增加做出额外贡献。
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引用次数: 0
Comparison of Placental Location on Ultrasound in Preeclampsia and Normotensive Pregnancy in Third Trimester. 子痫前期和血压正常妊娠第三孕期超声波显示胎盘位置的比较
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-04-27 eCollection Date: 2024-04-01 DOI: 10.4103/jmu.jmu_39_23
Mahima Aggarwal, Rajni Mittal, Jasmine Chawla
<p><strong>Background: </strong>Hypertensive disorders in pregnancy account for 15%-20% maternal and 20%-25% perinatal mortality. There is interest in predicting preeclampsia (PE) early in pregnancy to reduce PE and its subsequent complications. There is no cheap and easily available, reliable predictor for PE. Some studies have shown that the lateral location of placenta is associated with adverse pregnancy outcomes due to PE. The lateral placenta is yet to be proven as a strong predictor of PE to initiate preventive measures. Placental localization can be easily done on routine ultrasonography during pregnancy. In the light of these observations, a prospective study was done to study any association between PE and placental location by ultrasound in third trimester. Research Question: Is there any association between placental location on ultrasound and preeclampsia in third trimester? The objective is to study association between location of placenta and preeclampsia and compare placental location in normotensive pregnancies with that in PE in third trimester.</p><p><strong>Methods: </strong>A prospective comparative, case-control, observational study was conducted in the Department of Obstetrics and Gynecology at North DMC Medical College and Hindu Rao Hospital, Delhi, India, from August 2019 to April 2020. The study population included 200 pregnant women with singleton pregnancy in third trimester, without any medical disorders such as diabetes mellitus, hypertension, renal disease, cardiac disease, and coagulation disorder or smoking. One hundred women had preeclampsia and 100 were normotensive controls. Ultrasound was done after filling F form as per the Government of India guidelines to rule out sex determination, and placenta was localized by ultrasound. Placenta was classified as central when it was equally distributed between the right and left sides of the uterus irrespective of anterior, posterior, or fundal position and lateral when 75% or more of the placental mass was on one side of the midline. Placental location was compared in hypertensive and normotensive pregnancies.</p><p><strong>Results: </strong>Out of the total 200 women, 152 (76%) had central and 48 (24%) had lateral placenta. Ninety-two percent of controls and 60% of cases had central placenta. Forty percent of cases and only 8% normotensive women had lateral placenta. Lateral placenta was five times more frequent in presence of PE as compared to normotensive controls. Out of 152 women with central placenta, 92 (60.5%) women were normotensive but with lateral placenta, only 8 (16.7%) had normal blood pressure. PE was present in 83% of women with lateral placenta and in only 39.47% with central placenta. This difference was statistically significant as <i>P</i> < 0.0001 as per Chi-square test. This reflects a significant association between lateral position of placenta and occurrence of PE. As per odds ratio (0.1304) patients without lateral placenta had 90% protection a
背景:妊娠期高血压疾病导致 15%-20%的孕产妇和 20%-25%的围产儿死亡。人们对在妊娠早期预测子痫前期(PE)以减少子痫前期及其后续并发症很感兴趣。目前还没有廉价、易得、可靠的子痫前期预测指标。一些研究表明,胎盘侧位与 PE 导致的不良妊娠结局有关。胎盘侧位作为 PE 的有力预测指标,以启动预防措施还有待证实。胎盘定位可通过孕期常规超声波检查轻松完成。鉴于这些观察结果,我们进行了一项前瞻性研究,通过超声波检查来研究妊娠三个月时 PE 与胎盘位置之间是否存在关联。研究问题超声波显示的胎盘位置与妊娠三个月子痫前期之间是否存在关联?目的:研究胎盘位置与子痫前期之间的关系,并比较正常血压妊娠与第三孕期 PE 的胎盘位置:2019年8月至2020年4月,印度德里北DMC医学院和兴都拉奥医院妇产科开展了一项前瞻性比较、病例对照、观察性研究。研究对象包括 200 名怀孕三个月的单胎孕妇,她们没有任何疾病,如糖尿病、高血压、肾病、心脏病、凝血功能障碍或吸烟。其中 100 名妇女患有子痫前期,100 名妇女为血压正常的对照组。根据印度政府的指导方针,在填写 F 表格后进行超声波检查,以排除性别鉴定,并通过超声波确定胎盘的位置。当胎盘不分前方、后方或宫底位置均等地分布在子宫左右两侧时,胎盘被归类为中央型胎盘;当 75% 或以上的胎盘位于中线一侧时,胎盘被归类为侧型胎盘。对高血压孕妇和血压正常孕妇的胎盘位置进行比较:在总共 200 名孕妇中,152 名(76%)为中央胎盘,48 名(24%)为侧位胎盘。92%的对照组和 60% 的病例有中央胎盘。40%的病例和仅 8%的正常血压妇女患有侧边胎盘。与血压正常的对照组相比,患有 PE 的侧边胎盘发生率高出五倍。在152名患有中央型胎盘的妇女中,92名(60.5%)血压正常,但只有8名(16.7%)患有侧型胎盘的妇女血压正常。83% 患有侧边胎盘的妇女出现 PE,而只有 39.47% 患有中央胎盘的妇女出现 PE。根据卡方检验(Chi-square test),这一差异具有统计学意义(P < 0.0001)。这反映出胎盘侧位与 PE 的发生有明显的关联。根据几率比(0.1304),无侧位胎盘的患者对子痫前期有 90% 的保护作用:结论:中央胎盘比侧位胎盘更常见。结论:中央型胎盘比侧置胎盘更常见,侧置胎盘在高血压妇女中的出现率是中央型胎盘的五倍,这一差异具有统计学意义。胎盘位置对子痫前期的严重程度没有影响。
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引用次数: 0
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Journal of Medical Ultrasound
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