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Three-dimensional and Two-dimensional Shear Wave Elastography: Associations of Quantitative Elasticity Values with Prognostic Factors of Breast Cancer. 三维和二维剪切波弹性成像:定量弹性值与乳腺癌预后因素的关系。
IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-06-16 eCollection Date: 2025-10-01 DOI: 10.4103/jmu.JMU-D-24-00023
Jie Tian, Xin Liu, Chun Yu Chai, Jian Qiao Zhou

Background: The aim of the study was to investigate the correlation of three-dimensional (3D) and two-dimensional (2D) quantitative shear-wave elastography (SWE) with prognostic factors in invasive breast cancer.

Methods: Ninety-four female patients with 94 breast lesions were tested using B-mode ultrasound and SWE. 3D and 2D quantitative SWE characteristics, including elastic modulus standard deviation (ESD) and maximum elasticity (Emax), were evaluated. The pathological prognostic indicators for breast cancer were assessed, encompassing factors such as tumor dimensions, histological grade, lymph node involvement, the status of histologic biomarkers, and the classification of tumor subtypes. Associations between 3D and 2D quantitative SWE values and prognostic factors of breast tumors were analyzed.

Results: The quantitative parameters Emax and ESD exhibited a notable correlation with tumor size subgroups (3D: P = 0.002 and P = 0.024; 2D: P = 0.003 and P = 0.008), and had a positive correlation with tumor size (3D: Emax P = 0.379, P = 0.0002, ESD P = 0.234, P = 0.023; 2D: Emax P = 0.398, P = 0.000, ESD P = 0.361, P = 0.004). The Emax and ESD of breast cancer patients exhibiting lymph node metastasis were markedly elevated in comparison to those without lymph node metastasis (3D: P = 0.024 and P = 0.036; 2D: P = 0.031 and P = 0.011). Emax and ESD except for ESD in 3D SWE were markedly elevated in Ki-67-positive breast cancers than in negatively expressed breast cancers (3D: P = 0.033 and P = 0.105; 2D: P = 0.044 and P = 0.029). Combined BIRADS and 3D and 2D quantitative parameters demonstrated moderate diagnostic efficacy in predicting lymph node metastasis (area under the curve = 0.714).

Conclusion: 3D and 2D quantitative parameters Emax and ESD demonstrate significant associations with prognostic factors in invasive breast cancer, including tumor size, lymph node involvement, and Ki-67 expression.

背景:本研究的目的是探讨三维(3D)和二维(2D)定量剪切波弹性成像(SWE)与浸润性乳腺癌预后因素的相关性。方法:对94例女性乳腺病变进行b超和SWE检查。三维和二维定量SWE特征,包括弹性模量标准差(ESD)和最大弹性(Emax)进行了评估。评估乳腺癌的病理预后指标,包括肿瘤大小、组织学分级、淋巴结累及、组织学生物标志物状态和肿瘤亚型分类等因素。分析三维和二维定量SWE值与乳腺肿瘤预后因素的关系。结果:Emax、ESD定量参数与肿瘤大小亚组呈显著相关(3D: P = 0.002、P = 0.024; 2D: P = 0.003、P = 0.008),与肿瘤大小呈显著正相关(3D: Emax P = 0.379、P = 0.0002、ESD P = 0.234、P = 0.023; 2D: Emax P = 0.398、P = 0.000、ESD P = 0.361、P = 0.004)。有淋巴结转移的乳腺癌患者的Emax和ESD明显高于无淋巴结转移的乳腺癌患者(3D: P = 0.024和P = 0.036; 2D: P = 0.031和P = 0.011)。ki -67阳性乳腺癌中除3D SWE中的ESD外,Emax和ESD均显著高于阴性表达乳腺癌(3D: P = 0.033和P = 0.105; 2D: P = 0.044和P = 0.029)。BIRADS联合3D和2D定量参数预测淋巴结转移的诊断效果中等(曲线下面积= 0.714)。结论:三维和二维定量参数Emax和ESD与浸润性乳腺癌的预后因素有显著相关性,包括肿瘤大小、淋巴结累及程度和Ki-67表达。
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引用次数: 0
First Trimester Identification of a Recurrent Case of Short-rib Thoracic Dysplasia due to Novel NEK1 Variations with Small Thorax and Polydactyly. 由于新的NEK1变异导致的短肋胸发育不良伴小胸和多指畸形的妊娠早期复发病例的鉴定。
IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-06-11 eCollection Date: 2025-07-01 DOI: 10.4103/jmu.jmu_88_24
Yong-Shan Chen, Dong-Zhi Li
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引用次数: 0
Clinical Algorithm for Ultrasound-guided Facial and Neck Rejuvenation. 超声引导面部和颈部年轻化的临床算法。
IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-06-11 eCollection Date: 2025-07-01 DOI: 10.4103/jmu.JMU-D-24-00015
Sekina Alimova, Yehya Tlaiss, Victor Truten, John Warrak

The global rise in demand for minimally invasive esthetic procedures has underscored the need for enhanced precision and safety. This study presents a novel clinical algorithm integrating real-time ultrasound (US) guidance into facial and neck rejuvenation treatments to improve procedural outcomes. Conducted over four years with 56 patients, the study utilized high-frequency B-mode imaging, Doppler functionality, and superb microvascular imaging (SMI) to map anatomical structures, optimize treatment planning, and guide interventions. The algorithm follows a systematic, step-by-step protocol encompassing patient selection, anatomical assessment, procedure execution, and postoperative evaluation. Results indicated a significant improvement in procedural precision, with reduced complication rates and higher patient satisfaction. Notably, 85% of patients rated their outcomes as "much improved" or "very much improved" on the Global Aesthetic Improvement Scale (GAIS). The US-guided approach enabled more accurate filler placement, minimized vascular complications, and improved outcomes compared to traditional techniques. These findings support the integration of US diagnostics in esthetic practice to enhance safety, optimize results, and contribute to the evolving standards of care in non-surgical facial rejuvenation.

全球对微创美容手术需求的增长强调了提高精度和安全性的必要性。本研究提出了一种新的临床算法,将实时超声(US)引导整合到面部和颈部年轻化治疗中,以改善手术结果。该研究对56名患者进行了四年多的研究,利用高频b型成像、多普勒功能和高超微血管成像(SMI)来绘制解剖结构、优化治疗计划和指导干预。该算法遵循一个系统的、一步一步的协议,包括患者选择、解剖评估、手术执行和术后评估。结果显示手术精度显著提高,并发症发生率降低,患者满意度提高。值得注意的是,85%的患者在全球审美改善量表(GAIS)中将他们的结果评为“大大改善”或“非常改善”。与传统技术相比,美国引导的方法能够更准确地放置填充物,最大限度地减少血管并发症,并改善结果。这些发现支持美国诊断在美容实践中的整合,以提高安全性,优化结果,并有助于发展非手术面部年轻化的护理标准。
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引用次数: 0
Recurrent Fibroadenoma and Concomitant Mucinous Cancer with Ductal Carcinoma In situ Following Benign Phyllodes Tumor Excision: A Rare Case Report. 良性叶状瘤切除后复发纤维腺瘤并伴随黏液癌合并导管原位癌1例。
IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-06-11 eCollection Date: 2025-10-01 DOI: 10.4103/jmu.jmu_93_24
Pei-Shyuan Lee, Ming-Lin Tsai, Yu-Chi Chang, Shing-Huey Lin

A 37-year-old woman was diagnosed with a fibroadenoma (FA) with concomitant extensive spreading of ductal carcinoma in situ (DCIS) and multifocal mucinous carcinomas in 2022. Previously, she was first diagnosed with a FA and received excision in 2016. The initial clinical presentation was a palpable mass in the left breast. During periodic breast ultrasound examination in 2020, another newly developed tumor was found in the same region. A core biopsy revealed a fibroepithelial lesion. The patient received wide excision surgery. The final pathology report indicated a phyllodes tumor (PT) with a clear margin. All three events occurred in the same region (left breast, at 2 O'clock and 3-5 cm from the nipple). Our patient had a relapsed FA, which progressed into a benign PT and FA concomitant with DCIS and multifocal mucinous carcinomas. We report this case to highlight the need for continuous follow-up for FA cases even after complete resection and the possibility of recurrence with other fibroepithelial tumors.

一名37岁的女性于2022年被诊断为纤维腺瘤(FA)并伴有广泛扩散的导管原位癌(DCIS)和多灶性粘液癌。此前,她首次被诊断出患有FA,并于2016年接受了手术切除。最初的临床表现是左乳房可触及的肿块。在2020年定期乳腺超声检查中,在同一区域发现另一个新发肿瘤。核心活检显示纤维上皮病变。病人接受了大范围切除手术。最终病理报告显示为叶状瘤(PT),边缘清晰。这三个事件都发生在同一区域(左乳房,2点钟位置,距乳头3-5厘米)。我们的病人有一个复发的FA,发展为良性PT和FA合并DCIS和多灶性黏液癌。我们报告这个病例是为了强调FA病例即使在完全切除后也需要持续随访,以及其他纤维上皮肿瘤复发的可能性。
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引用次数: 0
Role of Ultrasonography in the Diagnosis of Chronic Appendicitis: An Observational Study of 400 Cases. 超声在慢性阑尾炎诊断中的作用:附400例观察研究。
IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-06-11 eCollection Date: 2025-10-01 DOI: 10.4103/jmu.jmu_67_24
Manohar Baburao Kachare, Zaid Peerpasha Inamdar, Sanjay B Kulkarni, Shabbirahmed Y Shaikh

Background: Chronic appendicitis is an uncommon clinical entity. Unlike acute appendicitis, the presence of nonspecific clinical features makes it a challenging diagnosis. Imaging modalities such as ultrasonography and computed tomography (CT) scans aid in the diagnosis of chronic appendicitis. CT scan has been widely described as the investigation of choice in previous studies. However, ultrasonography of the abdomen is a readily available and cheap alternative which provides comparable results and protects from radiation hazards. The aim of this study was to identify the core imaging features of chronic appendicitis on ultrasonography, their correlation with histopathology findings and to establish the most sensitive parameters for radiological diagnosis of chronic appendicitis.

Methods: This was an observational research study which employed a descriptive study design. All patients suffering from chronic/recurrent abdominal pain in the epigastric, periumbilical region or right lower quadrant were included in the study. The patients were subjected to history taking and clinical examination. Ultrasonography was performed by graded compression technique with high-frequency linear transducer. The specimens of the patients undergoing open or laparoscopic appendectomy were sent for histopathology. The preoperative ultrasonography diagnosis was confirmed on histopathology examination.

Results: Based on the statistical analysis of various major and minor criteria that were described in this study, the presence of localized pain in the right iliac fossa coupled with the ultrasonography features of irregularity of appendiceal lumen (sensitivity = 84.2%) and loss of wall stratification (sensitivity = 96.5%), showed a combined sensitivity of more than 99%, which were determined to be the most sensitive parameters for clinicoradiological diagnosis of chronic appendicitis.

Conclusion: Chronic appendicitis has often been misdiagnosed due to atypical symptoms at the time of presentation. Radiological investigations are used in the evaluation of patients with a high degree of clinical suspicion. This article has demonstrated the superiority of ultrasonography over CT scan for imaging of chronic appendicitis due to its advantages such as similar efficacy rates, higher spatial resolution in identifying features of chronic appendicitis, lack of ionizing radiation, cost-effectiveness, and easy availability. However, a definitive diagnosis is achieved by demonstrating evidence of chronic inflammation in the appendectomy specimen at histopathology.

背景:慢性阑尾炎是一种罕见的临床疾病。不像急性阑尾炎,非特异性临床特征的存在使其具有挑战性的诊断。成像方式,如超声和计算机断层扫描(CT)扫描有助于诊断慢性阑尾炎。在以往的研究中,CT扫描被广泛地描述为对选择的调查。然而,腹部超声检查是一种容易获得和便宜的替代方法,它提供了类似的结果,并保护免受辐射危害。本研究旨在探讨慢性阑尾炎超声影像的核心特征及其与组织病理学的相关性,为慢性阑尾炎的影像学诊断建立最敏感的参数。方法:采用描述性研究设计的观察性研究。所有在上腹部、脐周区域或右下腹患有慢性/复发性腹痛的患者都被纳入研究。对患者进行病史和临床检查。超声检查采用高频线性换能器梯度压缩技术。对开腹或腹腔镜阑尾切除术患者标本进行组织病理学检查。术前超声诊断经组织病理学检查证实。结果:通过对本研究各项主要和次要标准的统计分析,右侧髂窝局部疼痛的存在,加上阑尾管腔不规则(敏感性= 84.2%)和肠壁分层丧失(敏感性= 96.5%)的超声表现,其综合敏感性大于99%,是慢性阑尾炎临床放射学诊断最敏感的参数。结论:慢性阑尾炎常因表现不典型而被误诊。影像学检查用于临床高度怀疑的患者的评估。本文论证了超声检查在慢性阑尾炎影像学上优于CT扫描的优点,如显像率相近、识别慢性阑尾炎特征的空间分辨率较高、不需要电离辐射、成本效益高、易得等。然而,通过在组织病理学上证明阑尾切除标本中存在慢性炎症的证据,可以获得明确的诊断。
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引用次数: 0
Significance of Pelvic Floor Hiatus in Female Pelvic Organ Prolapse. 盆底裂孔在女性盆腔器官脱垂中的意义。
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-05-23 eCollection Date: 2025-04-01 DOI: 10.4103/jmu.JMU-D-25-00012
Jenn-Ming Yang, Wen-Chen Huang

Pelvic floor hiatus (PFH) is the pelvic floor passage through which the pelvic organs pass. Proper PFH closure is essential to maintaining normal pelvic organ support. PFH can be explored with urogenital hiatus or levator hiatus, according to different anatomical definitions. Factors affecting PFH include age, ethnicity, body mass index, levator ani muscle integrity, resting tone, and contraction force of pelvic floor muscle. The ineffectiveness of PFH to stay adequately closed is not only associated with pelvic floor disorders including pelvic organ prolapse (POP) but also accountable for recurrent POP after pelvic floor repairs. Advancing our comprehension of the mechanism of an enlarged PFH and how PFH enlargement affects pelvic floor support would promote better prevention strategies and improved treatments.

盆底裂孔(PFH)是骨盆器官通过的盆底通道。适当的PFH关闭对于维持正常的盆腔器官支持至关重要。根据不同的解剖定义,PFH可伴有泌尿生殖裂孔或提肛裂孔。影响PFH的因素包括年龄、种族、体重指数、提肛肌完整性、静息张力和盆底肌收缩力。PFH不能保持充分闭合不仅与盆腔器官脱垂(POP)等盆底疾病有关,而且也是盆底修复后复发性POP的原因。推进我们对PFH增大的机制的理解,以及PFH增大如何影响盆底支持,将促进更好的预防策略和改进治疗。
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引用次数: 0
The Pediatric Tri-POCUS Approach: Conceptual Review and Case Series. 儿科三pocus方法:概念回顾和病例系列。
IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-05-23 eCollection Date: 2025-04-01 DOI: 10.4103/jmu.JMU-D-24-00002
Daniel Palanca Arias, Marcos Clavero Adell, Victoria Estabén Boldova, José Enrique Alonso Formento, Ariada Ayerza Casas, Almudena Alonso Ojembarrena

Effective fluid management presents a significant challenge for pediatric intensivists. Enhanced ultrasound data that predict adverse outcomes, such as edema and venous congestion, can provide important information about optimal fluid management. The integration of bedside multiorgan ultrasound protocols (Multi-POCUS) mitigates the limitations of individual scoring systems, enabling more accurate fluid monitoring and management. The Tri-POCUS approach, described initially in adult patients, combines lung ultrasound, focused cardiac ultrasound, and venous excess ultrasound, and its application in the pediatric population is proposed. This study examines the Tri-POCUS approach from a pediatric perspective: we applied it to a cohort of critically ill pediatric patients with venous congestion admitted to a pediatric intensive care unit. Four cases are presented to demonstrate the bedside utility of the Tri-POCUS approach in critically ill children with the goal of monitoring venous congestion.

有效的流体管理是儿科重症医师面临的一个重大挑战。增强的超声数据预测不良后果,如水肿和静脉充血,可以提供最佳液体管理的重要信息。床边多器官超声协议(Multi-POCUS)的集成减轻了单个评分系统的局限性,实现了更准确的流体监测和管理。Tri-POCUS方法最初是在成人患者中描述的,它结合了肺超声、聚焦心脏超声和静脉超声,并提出了它在儿科人群中的应用。本研究从儿科角度考察了Tri-POCUS方法:我们将其应用于儿科重症监护病房的静脉充血危重儿科患者队列。四个案例提出,以证明床边效用的三pocus方法在重症儿童与监测静脉充血的目标。
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引用次数: 0
From Visualization to Automation: A Narrative Review of Deep Learning's Impact on Ultrasound-based Median Nerve Assessment. 从可视化到自动化:深度学习对超声正中神经评估的影响述评。
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-05-23 eCollection Date: 2025-04-01 DOI: 10.4103/jmu.JMU-D-25-00010
Chueh-Hung Wu, Che-Min Tsai, Po-Ling Kuo

Ultrasound imaging has emerged as a valuable tool in the diagnosis and management of peripheral nerve disorders. The integration of deep learning with ultrasound technology has shown remarkable potential in enhancing diagnostic accuracy and efficiency. This review focuses on the application of deep learning-based approaches in ultrasound diagnostics for peripheral nerve diseases, with particular emphasis on median nerve segmentation in carpal tunnel syndrome. Structured to provide a clear and thorough understanding of the current landscape and future directions, the paper is organized into several key sections: (1) an overview of the current state of the field, (2) research objectives and notable achievements, (3) challenges in dataset utilization specific to medical imaging, (4) trends in the development of deep learning models tailored for ultrasound analysis, and (5) potential future directions for research and clinical application. This review seeks to bridge the gap between technological advancements and clinical practice, potentially paving the way for more accurate and efficient diagnosis and treatment in the field of peripheral nerve disorders.

超声成像在周围神经疾病的诊断和治疗中已成为一种有价值的工具。深度学习与超声技术的结合在提高诊断准确性和效率方面显示出显著的潜力。本文综述了基于深度学习的方法在周围神经疾病超声诊断中的应用,特别强调了腕管综合征中正中神经分割的应用。为了提供对当前形势和未来方向的清晰透彻的理解,本文分为几个关键部分:(1)概述该领域的现状,(2)研究目标和显著成果,(3)针对医学成像的数据集利用的挑战,(4)为超声分析量身定制的深度学习模型的发展趋势,以及(5)研究和临床应用的潜在未来方向。本综述旨在弥合技术进步与临床实践之间的差距,为周围神经疾病领域更准确、更有效的诊断和治疗铺平道路。
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引用次数: 0
CME Test.
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-05-23 eCollection Date: 2025-04-01 DOI: 10.4103/jmu.jmu_2_25
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引用次数: 0
Treatment Outcomes of Extracorporeal Magnetic Innervation for Female Stress Urinary Incontinence. 体外磁神经支配治疗女性压力性尿失禁的效果。
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-05-23 eCollection Date: 2025-04-01 DOI: 10.4103/jmu.JMU-D-25-00022
Jenn-Ming Yang, Wen-Chen Huang

The present study aimed to review the literature on clinical studies of extracorporeal magnetic innervation (ExMI) for female stress urinary incontinence (SUI). Studies were compiled from PubMed from 1998 to 2025. Clinical studies published in English were included. Nine studies evaluating the effect of ExMI on urinary incontinence were retrieved. Most of the studies are small-sized, single-arm, short-term, and moderate to limited in quality. The efficacy of ExMI to treat SUI is not conclusive throughout studies. Adverse events of ExMI are rarely reported. Well-founded evidence to recommend ExMI as standard treatment for female SUI is still not well established.

本文对体外磁神经支配治疗女性压力性尿失禁(SUI)的临床研究进行综述。这些研究是从1998年到2025年的PubMed上收集的。用英文发表的临床研究也包括在内。我们检索了9项评价ExMI治疗尿失禁效果的研究。大多数研究是小规模、单组、短期、质量中等或有限的。在所有的研究中,ExMI治疗SUI的疗效尚无定论。ExMI的不良事件很少报道。推荐ExMI作为女性SUI标准治疗的证据尚不充分。
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引用次数: 0
期刊
Journal of Medical Ultrasound
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