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The role of holistic assessment, multidisciplinary diagnosis and treatment, and negative-pressure wound therapy with instillation in managing complex diabetic foot ulcers: a case-based discussion. 综合评估、多学科诊断和治疗以及负压伤口灌注治疗在管理复杂糖尿病足溃疡中的作用:基于病例的讨论。
IF 1 Q3 EMERGENCY MEDICINE Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.62347/UJRA7230
Shaobin Yu, Weiqiang Zhang, Xiaoyuan Wu, Yuhuan Zhao, Zhifeng Yang, Junyi He, Ronghua Yang

The etiology of diabetic foot ulcers (DFU) is multifactorial, encompassing neuropathy, peripheral arterial disease, and susceptibility to infection. The management of DFU remains challenging due to high recurrence rates and amputation risks. While various treatments exist, a standardized, effective approach integrating holistic care is essential. This paper presents a detailed analysis of two representative cases of complex DFU managed within our institution. Both patients underwent a structured process involving immediate holistic assessment, formation of an MDT to devise personalized treatment strategies, surgery, application of NPWTi, and structured post-discharge planning including health education. Eventually, both patients achieved successful wound closure without major amputation. The successful management of complex DFU necessitates a paradigm shift from isolated interventions to a comprehensive strategy. This strategy should encompass 1) early holistic patient assessment, 2) centralized coordination via an MDT for personalized care plans, 3) meticulous surgical debridement, 4) judicious use of advanced adjunctive therapies like NPWTi, and 5) robust post-discharge follow-up and patient education to prevent recurrence. This framework serves as a practical guide until further robust evidence emerges to refine these recommendations.

糖尿病足溃疡(DFU)的病因是多因素的,包括神经病变、外周动脉疾病和易感性感染。由于高复发率和截肢风险,DFU的治疗仍然具有挑战性。虽然存在各种治疗方法,但整合整体护理的标准化、有效方法至关重要。本文对我院管理的两例具有代表性的复杂DFU进行了详细分析。两名患者都接受了结构化的过程,包括即时整体评估,形成MDT以制定个性化治疗策略,手术,NPWTi的应用以及包括健康教育在内的结构化出院后计划。最终,两名患者都成功地完成了伤口闭合,没有进行大面积截肢。复杂DFU的成功管理需要从孤立干预到综合战略的范式转变。该策略应包括:1)早期患者整体评估;2)通过MDT进行个性化护理计划的集中协调;3)细致的手术清创;4)明智地使用先进的辅助疗法,如NPWTi; 5)强有力的出院后随访和患者教育,以防止复发。在出现进一步有力的证据来完善这些建议之前,本框架可作为实用指南。
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引用次数: 0
Treatment of paediatric subtrochanteric femoral fractures using titanium elastic nails: a single-center experience. 钛弹性钉治疗小儿股骨粗隆下骨折:单中心经验。
IF 1 Q3 EMERGENCY MEDICINE Pub Date : 2025-10-15 eCollection Date: 2025-01-01 DOI: 10.62347/WBTX6644
Latif Zafar Jilani, Mohammad Istiyak

Background: Subtrochanteric femoral fractures in children are uncommon but challenging to manage due to high mechanical stresses and their proximity to the growth plate. While the Titanium Elastic Nailing System (TENS) has proven effective for paediatric diaphyseal fractures, its role in subtrochanteric fractures is less well established.

Aim: The aim of this study was to evaluate the clinical and radiological outcomes of paediatric subtrochanteric femoral fractures treated with TENS, specifically assessing union rates, complications, and functional outcomes using Flynn's criteria.

Methods: We conducted a prospective observational study of 18 children aged 5-11 years with radiologicaly confirmed subtrochanteric femoral fractures treated using TENS at a tertiary care centre. Patient demographics, fracture patterns, associated injuries, time to surgery, postoperative immobilization, time to weight bearing, fracture union, complications, and outcomes were recorded and analysed.

Results: The mean age of patients was 7.7 years, with a male predominance (61%). The most common fracture patterns were oblique and spiral. Associated injuries were seen in 4 patients, and the average time to surgery was 2.1 days. Partial weight bearing was initiated by 4-5 weeks, and radiological union was achieved in all patients, with a mean union time of 9.5 weeks. Complications included limb length discrepancy (1 case), nail irritation (2 cases), and delayed union or malalignment (2 cases). According to Flynn's criteria, 72% had excellent, 22% good, and 6% satisfactory outcomes.

Conclusion: TENS is a safe, minimally invasive, and effective treatment for paediatric subtrochanteric femoral fractures in children aged 5-11 years. When applied with proper technique and patient selection, it results in reliable union, early mobilization, and favourable functional outcomes with minimal complications.

背景:儿童股骨粗隆下骨折并不常见,但由于高机械应力和靠近生长板,治疗难度很大。虽然钛弹性钉系统(TENS)已被证明对小儿骨干骨折有效,但其在粗隆下骨折中的作用尚不明确。目的:本研究的目的是评估经TENS治疗的儿童股骨粗隆下骨折的临床和放射学结果,特别是使用Flynn标准评估愈合率、并发症和功能结果。方法:我们对18名5-11岁的儿童进行了前瞻性观察研究,这些儿童在三级保健中心接受了放射学证实的股骨粗隆下骨折的TENS治疗。记录和分析患者人口统计学、骨折类型、相关损伤、手术时间、术后固定时间、负重时间、骨折愈合、并发症和结果。结果:患者平均年龄7.7岁,男性居多(61%)。最常见的骨折类型为斜型和螺旋型。合并损伤4例,平均手术时间2.1天。4-5周开始部分负重,所有患者均实现放射愈合,平均愈合时间为9.5周。并发症包括肢体长度不一致(1例),指甲刺激(2例),延迟愈合或不对齐(2例)。根据弗林的标准,72%的结果为优秀,22%为良好,6%为满意。结论:TENS治疗5-11岁儿童股骨粗隆下骨折安全、微创、有效。当采用适当的技术和患者选择时,可获得可靠的愈合,早期活动和良好的功能结果,并发症最少。
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引用次数: 0
Aetiology, factors associated with injury severity, and bacterial susceptibility patterns among burn patients in six selected hospitals in Uganda. 乌干达六家选定医院烧伤患者的病因学、与损伤严重程度相关的因素和细菌易感性模式。
IF 1 Q3 EMERGENCY MEDICINE Pub Date : 2025-10-15 eCollection Date: 2025-01-01 DOI: 10.62347/QNDA5725
Byamungu P Kagenderezo, Joshua Muhumuza, Mugisho M Leocadie, Funmileyi Awobajo, Selamo F Molen, Godefroy N Basara, Musa A Waziri, Franck K Sikakulya, Stephen M Kithinji, Emmanuel I Obeagu, Kiyaka M Sonye, Ibe Usman, Agwu Ezera, Okedi F Xaviour

Background: Globally, burn injury is of public health concern; it is a significant health problem in both children and older adult populations. In Africa and especially in Uganda, burn injuries remain a major cause of prolonged hospital stays, disability, disfigurement and death. A lot of factors may be associated with the injury severity of burn wounds. Bacterial microorganisms take short hours to invade the burn wound and can be identified in the burn wounds less than 24 hours old. When a patient is alive after 3 days following a burn, then the commonest cause of death is infection. Bacterial infection is still the serious complication that might compromise with the patient's life after the early phase of the management, and the bacterial pathogens isolated from these wounds might still be resistant to the most common used antibiotics in our setting.

Objectives: The aim of this study was to determine the most common etiology, the factors associated with injury severity, and the bacterial susceptibility patterns of burn patients in six selected hospitals in Uganda.

Methods: This cross-sectional study was conducted in the departments of surgery at the six selected hospitals from April to July 2022.

Results: Around 76 patients admitted to those hospitals with burns during our study period were included. Those who were very severe without caretakers eligible to consent for them were excluded. The average age was 17.7 years. There were slightly more males with a male-to-female ratio of 1.05. The majority were from the rural areas accounting for 76.3%. The common etiology was thermal, accounting for 80.8%, dominated by scalds (60.5%). Patients with burn wounds at the sites mandating admission were 22 times more likely to have a severe injury. The most common organism isolated was staphylococcus aureus accounting for 45.2%, followed by Pseudomonas, accounting for 15.5%, and they % were resistant to most of the antibiotics used in our study. Despite that identified bacteria were resistant to most of antibiotics, a good number of them were sensitive to imipenem, amikacin, ciprofloxacin, and cloxacillin.

Conclusions: Implementation of burn infection control policies is needed. There is a need to include sites mandating admission in the parameters of the ABSI score. Based on microorganisms isolated, empirical treatment with ciprofloxacin or cloxacillin should be considered.

背景:在全球范围内,烧伤是一个令人关注的公共卫生问题;这对儿童和老年人都是一个重大的健康问题。在非洲,特别是在乌干达,烧伤仍然是长期住院、残疾、毁容和死亡的一个主要原因。许多因素可能与烧伤创面的损伤严重程度有关。细菌微生物可以在短时间内侵入烧伤创面,并且可以在不到24小时的烧伤创面中发现。如果病人在烧伤后3天还活着,那么最常见的死亡原因是感染。在治疗的早期阶段,细菌感染仍然是严重的并发症,可能会危及患者的生命,并且从这些伤口中分离出的细菌病原体可能仍然对我们环境中最常用的抗生素具有耐药性。目的:本研究的目的是确定乌干达六家选定医院烧伤患者最常见的病因、与损伤严重程度相关的因素以及细菌敏感性模式。方法:于2022年4月至7月在6家医院的外科进行横断面研究。结果:在我们的研究期间,约有76例烧伤患者入院。那些非常严重而没有合格的看护人同意的人被排除在外。平均年龄为17.7岁。男性略多,男女比例为1.05。以农村地区居多,占76.3%。病因以热伤为主,占80.8%,以烫伤为主,占60.5%。在强制入院地点有烧伤的病人发生严重伤害的可能性是其他病人的22倍。分离出的细菌中最常见的是金黄色葡萄球菌,占45.2%,其次是假单胞菌,占15.5%,它们对我们研究中使用的大多数抗生素都有耐药性。尽管鉴定出的细菌对大多数抗生素耐药,但其中相当一部分对亚胺培南、阿米卡星、环丙沙星和氯西林敏感。结论:实施烧伤感染控制政策是必要的。有必要在ABSI分数的参数中包括强制入学的网站。根据分离的微生物,应考虑用环丙沙星或氯西林进行经验性治疗。
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引用次数: 0
The impact of resuscitation strategies on burn patient outcomes: Parkland vs. modified Brooke's. 复苏策略对烧伤患者预后的影响:Parkland vs.改良Brooke。
IF 1 Q3 EMERGENCY MEDICINE Pub Date : 2025-10-15 eCollection Date: 2025-01-01 DOI: 10.62347/UMYO8822
Abdulwhab M Alotaibi, Naif A Albulayhid, Khalid A Aljabr, Abdullah M Aldawsari, Abdulaziz M Alghamdi, Abdullah A Balhamar, Ibtisam S Alamri, Abdullh AlQhtani, Abdulaziz Alabdulkarim

Objectives: Over-resuscitation is a formidable complication of burn resuscitation and increased morbidity and mortality. Currently, the Advanced Trauma Life Support recommends using a modified Brooke's formula to minimise its incidence; however, supporting evidence is very limited. We aimed to compare the resuscitative and clinical outcomes between the Parkland and modified Brooke's formulas in patients with burn trauma.

Methods: A retrospective cohort study was conducted through a chart review of patients admitted to the burn unit. The patients were divided into two groups: Group 1 (2017-2019) was resuscitated using Parkland's formula and Group 2 (2020-2022) with modified Brooke's formula. The main outcome measures were mortality rate, length of stay, complication rate exceeding the Ivy index (250 mL/kg) in the first 24 h, and overall fluid administered in the first 24 h.

Results: We included 125 patients, of whom fifty-five were resuscitated using Parkland's formula and seventy using the modified Brooke's formula. Patients in group 1 had higher resuscitation volume (5.04 vs. 3.37 mL/kg/total body surface area, P < 0.0001) and were more likely to exceed the Ivy index (250 mL/kg) (32.73% vs. 12.86%, P = 0.0074) in the first 24 h compared to those in group 2. There were no significant differences in clinical outcomes between the two groups.

Conclusions: The modified Brooke's formula resulted in lower resuscitative volumes in the first 24 h than Parkland's formula, with no differences in complication rates. Our findings are consistent with currently recommended guidelines.

目的:过度复苏是烧伤复苏的一个可怕的并发症,增加了发病率和死亡率。目前,高级创伤生命支持建议使用改进的布鲁克公式来减少其发生率;然而,支持证据非常有限。我们的目的是比较Parkland和改良Brooke配方对烧伤患者的复苏和临床结果。方法:回顾性队列研究通过对入院烧伤科患者的图表回顾。将患者分为两组:第一组(2017-2019年)采用Parkland配方进行复苏,第二组(2020-2022年)采用改良Brooke配方进行复苏。主要观察指标为死亡率、住院时间、前24小时并发症超过Ivy指数(250 mL/kg)的发生率以及前24小时的总输液量。结果:我们纳入125例患者,其中55例使用Parkland公式复苏,70例使用改良的Brooke公式复苏。与2组相比,1组患者在前24 h复苏量更高(5.04 vs. 3.37 mL/kg/体表面积,P < 0.0001),超过Ivy指数(250 mL/kg)的可能性更大(32.73% vs. 12.86%, P = 0.0074)。两组临床结果无显著差异。结论:改良后的Brooke配方在前24 h的复苏量低于Parkland配方,并发症发生率无差异。我们的发现与目前推荐的指南一致。
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引用次数: 0
Combined pudendal and sciatic nerve palsy following intramedullary nailing in fracture shaft femur: a rare case report. 股骨骨干骨折髓内钉治疗合并阴部及坐骨神经麻痹1例。
IF 1 Q3 EMERGENCY MEDICINE Pub Date : 2025-10-15 eCollection Date: 2025-01-01 DOI: 10.62347/KSZY2789
Latif Zafar Jilani, Mohammad Istiyak, Madhav Chowdhary, Arindam Kumar Bhowmik

Traction tables have been widely used by orthopaedic surgeons for the management of femoral shaft fractures. Although complications associated with their use are uncommon, they can still occur. Among neurological complications, sciatic and pudendal nerve palsies are the most frequently reported. Recognizing the potential causes and analyzing these complications are crucial for raising awareness among surgeons and implementing preventive strategies to enhance patient safety during surgical procedures. A 22-year-old male sustained a comminuted fracture of the left femoral shaft following a road traffic accident. The patient had an intact distal neurovascular status (DNVS) at presentation. Open reduction and internal fixation (ORIF) with femoral interlocking nail (FIN) was done using a traction table. Post-operatively, he developed signs of both sciatic and pudendal nerve palsy. The simultaneous occurrence of pudendal and sciatic nerve palsy is rare. In this case, pudendal nerve palsy was likely caused by prolonged traction with sustained hip adduction throughout the procedure, while sciatic nerve palsy was attributed to postoperative hematoma formation. To minimize such complications, it is advisable to limit soft tissue dissection during femoral shaft fracture reduction and promptly release traction after interlocking screw placement. Additionally, adherence to a "tourniquet safety protocol" that is, releasing traction every 120 minutes in prolonged surgeries can be beneficial. Hip adduction beyond the neutral position should also be avoided to reduce the risk of nerve injury.

牵引台已被骨科医生广泛应用于股骨干骨折的治疗。虽然与使用相关的并发症并不常见,但仍有可能发生。在神经系统并发症中,坐骨神经和阴部神经麻痹是最常见的报道。认识到潜在的原因并分析这些并发症对于提高外科医生的意识和实施预防策略以提高手术过程中患者的安全至关重要。一名22岁男性在一次道路交通事故中左股骨干粉碎性骨折。患者在就诊时远端神经血管状态(DNVS)完好。采用牵引台进行股骨交锁钉切开复位内固定(ORIF)。术后,患者出现坐骨神经和阴部神经麻痹的症状。同时发生阴部和坐骨神经麻痹是罕见的。在本例中,阴部神经麻痹可能是由于整个手术过程中持续的髋关节内收引起的,而坐骨神经麻痹则是由于术后血肿形成引起的。为了减少此类并发症,建议在股骨干骨折复位期间限制软组织剥离,并在联锁螺钉置入后及时解除牵引。此外,坚持“止血带安全协议”,即在长时间手术中每120分钟释放牵引力是有益的。也应避免髋关节内收超过中立位,以减少神经损伤的风险。
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引用次数: 0
Virtual reality-based functional recovery in burn population: a systematic review. 基于虚拟现实的烧伤人群功能恢复:系统综述。
IF 1 Q3 EMERGENCY MEDICINE Pub Date : 2025-10-15 eCollection Date: 2025-01-01 DOI: 10.62347/XLAP3706
Hafiz Muddassir Riaz, Muhammad Naveed Babur, Haroon Mansha, Muhammad Sanaullah, Idrees Ahmed Zahoor, Saleh Shah

Objective: To evaluate the effectiveness of virtual reality-based interventions in promoting functional recovery among individuals with burn injuries.

Data sources: PubMed/Medline, Scopus, Ovid, CINAHL, PEDro, Google Scholar, and Cochrane Library.

Methods: Multiple data sources were explored from beginning to March 31, 2024, with study design of randomized clinical trials describing Range of Motion, enhanced ability for self-care (ADLs) and independence, quality of life in adult with burn injury. ROM was primarily measured using goniometers and electronic digital goniometers to assess the degrees of movement at affected joints before and after VR-based rehabilitation sessions. Two independent authors analyzed the results and selected the data. Cochrane Criteria Risk of Bias version 2 was used to measure risk of bias. Patient demographics, treatment regimen and outcome measuring tool, results and change in the patients' conditions were also extracted. Each study was appraised to check the level of evidence.

Results: 8 publications were selected with a total of 293 patients included in these studies. Level of evidence analysis revealed that 8 studies were classified as level of evidence A2. The lowest PEDro score was 6 for one study only while other studies scored 7, 8, and 9 accordingly. In this review, seven studies were categorized as low risk of bias, while one study had some risk of bias. Our results showed that virtual reality can increase range of motion, enhanced ability for Self-Care (ADLs) and independence, improved quality of life in patients with burn injury, though strength of conclusion for mobility and ADLs was moderate.

Conclusion: Preliminary evidence indicates that virtual reality "V.R." interventions could be beneficial in promoting functional recovery in patients with burn injuries. The studies reviewed suggest Virtual Reality can reduce pain during rehabilitation, improve range of motion, and increase patient engagement. However, the limited number of studies and the variability in VR methods and outcome measures restrict the generalizability of these findings. Further rigorous research with standardized protocols is needed to validate these results and guide clinical practice. Future investigations should aim for larger sample sizes and longer follow-up periods to thoroughly evaluate the effectiveness of VR in burn rehabilitation.

目的:评价基于虚拟现实的干预在促进烧伤患者功能恢复中的有效性。数据来源:PubMed/Medline, Scopus, Ovid, CINAHL, PEDro,谷歌Scholar, Cochrane Library。方法:从开始到2024年3月31日,利用多个数据来源进行研究,设计随机临床试验,描述成人烧伤患者的运动范围、自我护理能力和独立性增强、生活质量。ROM主要使用角计和电子数字角计测量,以评估vr康复前后受影响关节的运动程度。两位独立作者分析了结果并选择了数据。采用Cochrane标准风险偏倚第2版来测量偏倚风险。还提取了患者人口统计资料、治疗方案和结果测量工具、结果和患者病情的变化。对每项研究进行评估以检查证据水平。结果:入选8篇文献,共纳入293例患者。证据水平分析显示,8项研究被列为证据水平A2。只有一项研究的最低PEDro评分为6分,其他研究的评分分别为7分、8分和9分。在本综述中,7项研究被归类为低偏倚风险,1项研究有一定偏倚风险。我们的研究结果表明,虚拟现实可以增加烧伤患者的活动范围,增强自我护理能力(ADLs)和独立性,改善生活质量,尽管活动能力和ADLs的结论强度中等。结论:初步证据表明,虚拟现实(vr)干预有助于促进烧伤患者的功能恢复。这些研究表明,虚拟现实可以减轻康复期间的疼痛,改善活动范围,并增加患者的参与度。然而,研究数量有限,VR方法和结果测量的可变性限制了这些发现的普遍性。需要进一步严格的标准化研究来验证这些结果并指导临床实践。未来的研究应以更大的样本量和更长的随访时间为目标,以彻底评估VR在烧伤康复中的有效性。
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引用次数: 0
Femoral nerve palsy following total hip arthroplasty via posterolateral approach: a report of two cases and literature review. 经后外侧入路全髋关节置换术后股神经麻痹2例报告并文献复习。
IF 1 Q3 EMERGENCY MEDICINE Pub Date : 2025-10-15 eCollection Date: 2025-01-01 DOI: 10.62347/HDJK4613
Latif Zafar Jilani, Mohammad Istiyak

Femoral nerve palsy is a rare but serious complication following total hip arthroplasty (THA), particularly when performed through the posterolateral approach. Early diagnosis and prompt rehabilitation are crucial for functional recovery. We report two cases of femoral nerve palsy following THA, highlighting the clinical course, management, and outcomes. The first case involved a 53-year-old male with ankylosing spondylitis that underwent right-sided uncemented THA via the posterolateral approach. Postoperatively, he developed femoral nerve palsy, likely due to skin traction applied for residual hip flexion contracture. Early removal of traction, initiation of physiotherapy, and use of a static knee brace led to gradual recovery, with full restoration of quadriceps function by one year. The second case involved a 46-year-old obese female with a history of hip tuberculosis who underwent uncemented THA via the posterolateral approach. She developed femoral nerve palsy immediately postoperatively, likely related to intraoperative retractor placement difficulties due to tight soft tissues. Early mobilization and physiotherapy led to complete recovery of quadriceps strength within six months. Femoral nerve palsy, though uncommon after posterolateral THA, can significantly impact postoperative recovery. Awareness of risk factors such as soft tissue tightness and traction, combined with early diagnosis, rehabilitation, and supportive bracing, can lead to favorable outcomes. Surgeons must be cautious during soft tissue handling and retractor placement to minimize this complication.

股神经麻痹是全髋关节置换术(THA)后罕见但严重的并发症,特别是经后外侧入路手术。早期诊断和及时康复对功能恢复至关重要。我们报告两例髋关节置换术后股骨神经麻痹的病例,强调其临床过程、处理和结果。第一例患者为53岁男性强直性脊柱炎患者,经后外侧入路行右侧无骨水泥THA。术后,患者出现股神经麻痹,可能是由于残余髋屈曲挛缩进行皮肤牵引所致。早期解除牵引力,开始物理治疗,并使用静态膝关节支架导致逐渐恢复,股四头肌功能在一年内完全恢复。第二例患者为46岁肥胖女性,有髋关节结核病史,经后外侧入路行非骨水泥THA。术后立即出现股神经麻痹,可能与术中软组织紧绷导致牵开器放置困难有关。早期活动和物理治疗使股四头肌力量在6个月内完全恢复。股神经麻痹,虽然不常见后外侧THA术后,可显著影响术后恢复。意识到危险因素,如软组织松紧和牵拉,结合早期诊断、康复和支持支架,可以导致良好的结果。外科医生在处理软组织和放置牵开器时必须谨慎,以尽量减少这种并发症。
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引用次数: 0
From suspected joint tuberculosis to gouty arthritis: a diagnostic journey. 从疑似关节结核到痛风性关节炎:诊断之旅。
IF 1 Q3 EMERGENCY MEDICINE Pub Date : 2025-08-15 eCollection Date: 2025-01-01 DOI: 10.62347/PBRZ2450
Latif Zafar Jilani, Mohammad Istiyak, Arindam Kumar Bhowmik, Akash Sudarsan

Gout is a metabolic disorder characterized by hyperuricemia, leading to the deposition of monosodium urate crystals in joints and soft tissues. It commonly affects the first metatarso-phalangeal (MTP) joint, but atypical presentations can pose significant diagnostic challenges. In this report, we describe a rare case of gouty arthritis affecting the proximal interphalangeal (PIP) joint of the second toe, which was initially suspected to be a case of joint tuberculosis. A 38-year-old male presented with a painful swelling over the second toe for two months, with imaging and laboratory findings suggesting an infectious etiology. Despite clinical suspicion of tuberculosis, histopathological examination of the lesion confirmed the presence of amorphous eosinophilic material with chronic inflammatory infiltrate and giant cell reaction, indicative of gout. Subsequent serum uric acid evaluation revealed hyperuricemia, leading to a definitive diagnosis. The patient underwent surgical evacuation of the tophaceous deposits followed by medical management with colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs), and allopurinol. Postoperative follow-up demonstrated complete resolution of symptoms with no recurrence. Aim of the study: This case report aims to highlight the diagnostic challenges of atypical gout presentations, particularly when mimicking infectious conditions such as tuberculosis. It underscores the importance of maintaining a broad differential diagnosis, utilizing histopathology for confirmation, and considering gout even in uncommon anatomical locations.

痛风是一种以高尿酸血症为特征的代谢紊乱,导致关节和软组织中尿酸钠晶体的沉积。它通常影响第一跖指骨(MTP)关节,但不典型的表现可能带来重大的诊断挑战。在本报告中,我们描述了一个罕见的痛风性关节炎影响第二趾近端指间关节(PIP)的病例,最初怀疑是关节结核的病例。一名38岁男性表现为第二个脚趾疼痛肿胀两个月,影像学和实验室结果提示感染性病因。尽管临床怀疑为结核,但病变的组织病理学检查证实存在无定形嗜酸性物质,伴慢性炎症浸润和巨细胞反应,提示痛风。随后的血清尿酸评估显示高尿酸血症,导致明确的诊断。患者接受手术清除风疹沉积物,随后使用秋水仙碱、非甾体抗炎药(NSAIDs)和别嘌呤醇进行治疗。术后随访显示症状完全缓解,无复发。研究目的:本病例报告旨在强调非典型痛风表现的诊断挑战,特别是当模仿传染性疾病如结核病时。它强调了保持广泛的鉴别诊断的重要性,利用组织病理学进行确认,甚至在不常见的解剖位置考虑痛风。
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引用次数: 0
Reconstruction of nose defects using external temporoparietal fascia prefabricated forehead flap - an innovative surgical approach. 颞顶骨外筋膜预制额瓣修复鼻缺损的一种创新手术方法。
IF 1 Q3 EMERGENCY MEDICINE Pub Date : 2025-08-15 eCollection Date: 2025-01-01 DOI: 10.62347/XTYV9971
Huili Wang, Ning Liu, Xiaodong Ni, Yufeng Liu

Nasal reconstruction remains one of the most complex challenges in reconstructive plastic surgery due to its intricate three-dimensional architecture and functional demands. While the forehead flap has emerged as the gold standard for nasal reconstruction, conventional techniques inevitably produce conspicuous longitudinal forehead scarring at the pedicle site. We present an innovative approach combining external temporoparietal fascia prefabrication (E-TPFF) with tissue expansion technology to address these limitations. This article aims to enhance the existing method to meet the demand for nasal defect repair while eliminating the operation's drawbacks. Our modified technique offers three significant advantages: (i) complete elimination of visible forehead scarring through an external temporoparietal fascia prefabricated forehead flap (E-TPFF); (ii) providing a flap with reliable vascular supply through temporoparietal fascia prefabrication, and (iii) generation of sufficient flap volume and pedicle length to accommodate even extensive maxillofacial defects. Preliminary results demonstrate that the E-TPFF technique maintains all benefits of traditional forehead flaps while overcoming their most notable aesthetic drawbacks, representing a substantial advancement in facial reconstructive surgery.

由于其复杂的三维结构和功能要求,鼻重建仍然是重建整形外科中最复杂的挑战之一。虽然前额皮瓣已成为鼻重建的金标准,但传统技术不可避免地会在蒂部位产生明显的纵向前额疤痕。我们提出了一种创新的方法,将颞顶外筋膜预制(E-TPFF)与组织扩张技术相结合,以解决这些局限性。本文旨在对现有方法进行改进,以满足鼻缺损修复的需求,同时消除手术的弊端。我们改良的技术有三个显著的优点:(i)通过颞顶外筋膜预制前额皮瓣(E-TPFF)完全消除可见的前额疤痕;(ii)通过颞顶筋膜预制提供可靠的血管供应的皮瓣,(iii)产生足够的皮瓣体积和蒂长度以适应广泛的颌面缺损。初步结果表明,E-TPFF技术保留了传统前额皮瓣的所有优点,同时克服了其最显著的美学缺陷,代表了面部重建手术的实质性进步。
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引用次数: 0
Short versus long proximal femoral nail anti-rotation-II (PFNA-II) in the management of unstable intertrochanteric fractures. 短与长股骨近端钉抗旋转- ii (PFNA-II)治疗不稳定转子间骨折。
IF 1 Q3 EMERGENCY MEDICINE Pub Date : 2025-08-15 eCollection Date: 2025-01-01 DOI: 10.62347/LRTZ6852
Latif Zafar Jilani, Mohd Saleh, Mohammad Baqar Abbas, Sohail Ahmad, Abdul Qayyum Khan, Asad Khan
<p><strong>Objectives: </strong>Unstable intertrochanteric (IT) fractures, particularly in elderly patients with low bone mineral density, pose significant treatment challenges. Proximal femoral nail anti-rotation-II (PFNA-II) is widely used, but the optimal implant length (short vs. long) remains debated. The objective of this study was to compare the clinical and functional outcomes of short versus long PFNA-II implants in unstable IT fractures.</p><p><strong>Methods: </strong>A prospective comparative study was conducted at a tertiary hospital from November 2018 to November 2020. Adult patients (age ≥18) with recent (≤3 weeks) unstable IT femur fractures were included. Unstable fractures were defined by comminution of the posteromedial cortex, a compromised lateral wall (including reverse obliquity), or subtrochanteric extension. Patients with pathological fractures (other than osteoporosis), open fractures, polytrauma, pre-existing ipsilateral hip pathology, or non-ambulatory status were excluded. Patients were allocated to short PFNA-II (n=38) or long PFNA-II (n=40) groups based on the surgeon's intraoperative judgment (no randomization). All patients underwent standard reduction on a fracture table and fixation with PFNA-II. Postoperative mobilization and weight-bearing protocols were adjusted according to fracture stability and fixation quality. Outcome measures included fracture union time, complications, and the Harris Hip Score (HHS). Statistical significance was set at P<0.05.</p><p><strong>Results: </strong>Both groups had similar demographics, fracture types, and surgical durations (P>0.05). Fracture union was achieved in 94.7% (36/38) of short-nail patients and 90% (36/40) of long-nail patients, with no significant difference in union rates or time to union (mean ~14 weeks, P>0.05). The short PFNA-II group demonstrated a significantly higher final HHS (87.2±7.1 vs. 82.3±7.8, P=0.03), with 89.5% achieving good/excellent outcomes vs. 62.5% in the long-nail group. Postoperative complications differed in pattern: anterior thigh pain was more frequent in short nails (15.8% vs. 2.5%), whereas mechanical complications (varus collapse >5°, helical blade lateral migration) were more common in long nails (15% vs. 5.3% varus collapse; 10% vs. 2.6% blade migration). However, overall complication rates were not significantly different between groups (P=0.17). No deep infections, implant breakage, or cut-out occurred in either group.</p><p><strong>Conclusion: </strong>PFNA-II fixation is effective for unstable IT fractures with high union rates and low major complication rates in both implant groups. Short PFNA-II nails yielded superior functional outcomes and fewer mechanical complications compared to long nails in similar unstable fracture patterns. These findings suggest that implant length plays a crucial role in optimizing patient outcomes. In most cases of unstable IT fractures, a short PFNA-II appears advantageous, though patient anatomy (
目的:不稳定转子间骨折(IT),特别是在低骨密度的老年患者中,给治疗带来了重大挑战。股骨近端钉抗旋转- ii (PFNA-II)被广泛使用,但最佳内钉长度(短与长)仍存在争议。本研究的目的是比较短PFNA-II植入物与长PFNA-II植入物治疗不稳定IT骨折的临床和功能结果。方法:于2018年11月至2020年11月在某三级医院进行前瞻性比较研究。纳入近期(≤3周)不稳定IT股骨骨折的成年患者(年龄≥18岁)。不稳定骨折的定义是后内侧皮质粉碎,外侧壁受损(包括反向倾斜)或转子下延伸。排除病理性骨折(骨质疏松症除外)、开放性骨折、多发创伤、既往同侧髋关节病变或非活动状态的患者。根据外科医生术中判断,将患者分为短PFNA-II组(n=38)和长PFNA-II组(n=40)(无随机化)。所有患者均在骨折台上进行标准复位并使用PFNA-II固定。根据骨折稳定性和固定质量调整术后活动和负重方案。结果测量包括骨折愈合时间、并发症和Harris髋关节评分(HHS)。结果:两组患者的人口学特征、骨折类型、手术时间相似(P < 0.05)。短钉患者骨折愈合率为94.7%(36/38),长钉患者骨折愈合率为90%(36/40),愈合率和愈合时间(平均14周,P < 0.05)差异无统计学意义。短PFNA-II组最终HHS(87.2±7.1比82.3±7.8,P=0.03)明显高于长钉组,89.5%达到良/优疗效,而长钉组为62.5%。术后并发症在模式上有所不同:短指甲中大腿前部疼痛更常见(15.8%比2.5%),而机械并发症(内翻塌陷bbb50°,螺旋刀片外侧移动)在长指甲中更常见(15%比5.3%内翻塌陷;10%比2.6%刀片移动)。两组间并发症发生率差异无统计学意义(P=0.17)。两组均未发生深部感染、种植体断裂、切出。结论:两组PFNA-II内固定治疗不稳定IT骨折均有效,愈合率高,主要并发症发生率低。在类似的不稳定骨折类型中,与长钉相比,短PFNA-II钉具有更好的功能结果和更少的机械并发症。这些发现表明,种植体长度在优化患者预后方面起着至关重要的作用。在大多数不稳定的IT骨折病例中,较短的PFNA-II似乎是有利的,尽管在选择植入物长度时应考虑患者的解剖结构(如股骨极端弯曲)和骨折形态。
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引用次数: 0
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International Journal of Burns and Trauma
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