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HIV/AIDS and older adults in Cameroon: Emerging issues and implications for caregiving and policy-making. 喀麦隆的艾滋病毒/艾滋病与老年人:新出现的问题及其对护理和决策的影响。
IF 1.1 4区 医学 Q2 Social Sciences Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1433059
Perpetua Lum Tanyi, André Pelser, Joseph Okeibunor

The burden of human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS) on the elderly population in three divisions within the Northwest Region of Cameroon was examined. Data for this paper were extracted from a larger study which had been conducted concerning the burden of HIV infection and AIDS on the older adults in the Northwest Region of Cameroon. Using in-depth interviews (IDIs) and focus group discussions (FGDs), data were collected from 36 participants who were purposively selected from the three divisions which had been chosen randomly. 6 FGD sessions were held with 30 women aged 60 years and above and who were affected by HIV infection and AIDS, while IDIs sessions were held with 6 male community leaders. The results revealed that HIV infection and AIDS has added another dimension to the role of older persons. HIV infection and AIDS affects older people in diverse ways, as they have to look after themselves, their sick children and are often also left to look after their grandchildren orphaned by HIV infection and AIDS. These emerging issues in their lives make them vulnerable to health, social, economic and psychological challenges, and place a burden on them as caregivers instead of being cared for in their old age. Apart from increased direct expenditures, taking care of victims of HIV infection and AIDS requires older people to stay away from social, religious and community activities. The results showed that the loss of a child to HIV infection and AIDS affects the economic/financial well-being, participation in social/religious interactions as well as the community activities of older people participants. The implications of these findings for caregiving and social policy are discussed.

对喀麦隆西北地区三个省老年人口的人体免疫缺陷病毒(艾滋病毒)感染和获得性免疫缺陷综合症(艾滋病)负担进行了调查。本文的数据摘自一项关于喀麦隆西北地区老年人艾滋病毒感染和艾滋病负担的大型研究。采用深度访谈(IDIs)和焦点小组讨论(fgd),从随机选择的三个部门中有意选择的36名参与者收集数据。与30名60岁及以上感染艾滋病毒和艾滋病的妇女举行了6次妇女健康评估会议,与6名男性社区领导人举行了妇女健康评估会议。结果显示,艾滋病毒感染和艾滋病为老年人的作用增加了另一个层面。艾滋病毒感染和艾滋病以各种方式影响老年人,因为他们必须照顾自己和生病的子女,而且往往还要照顾因感染艾滋病毒和艾滋病而成为孤儿的孙辈。他们生活中出现的这些新问题使他们容易受到健康、社会、经济和心理挑战的影响,并使他们成为照顾者的负担,而不是在老年时得到照顾。除了增加直接支出外,照顾艾滋病毒感染和艾滋病受害者要求老年人远离社会、宗教和社区活动。结果表明,儿童死于艾滋病毒感染和艾滋病会影响老年人的经济/财务状况、社会/宗教互动的参与以及社区活动。讨论了这些发现对护理和社会政策的影响。
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引用次数: 11
The pull of soccer and the push of Xhosa boys in an HIV and drug abuse intervention in the Western Cape, South Africa. 在南非西开普省的一项艾滋病和药物滥用干预活动中,足球对科萨男孩的拉力和推力。
IF 1.1 4区 医学 Q2 Social Sciences Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1541024
Melissa Medich, Deborah Mindry, Mark Tomlinson, Mary Jane Rotheram-Borus, Jason Bantjes, Dallas Swendeman

There is growing interest in engaging men and boys in health and development programmes targeting the intersection of HIV risk, substance abuse, and violence. Understanding the conceptualisations of masculinities or masculine identities that shape both behaviours and opportunities for intervention is central to advancing the global agenda to engage men in health and development interventions. This paper examines an intervention using soccer and job training to engage and deliver activities for HIV prevention, substance abuse, and gender-based violence in a South African township. A literature review provides theoretical, historical and social context for the intersection of gender, masculinity, soccer, violence, and sexual relationships. Qualitative data from in-depth interviews and focus groups is analysed using theoretical and contextual frames to elucidate the negotiation of shifting, contradictory, and conflicting masculine roles. Results highlight how changing risky, normative behaviours among young men is a negotiated process entailing men's relationships with women and with other men.

让男性和男童参与针对艾滋病风险、药物滥用和暴力交叉问题的健康与发展计划的兴趣与日俱增。了解塑造男性行为和干预机会的男性概念或男性身份,对于推动全球议程,让男性参与健康与发展干预至关重要。本文研究了一项干预措施,该措施利用足球和工作培训,在南非的一个乡镇开展艾滋病预防、药物滥用和性别暴力活动。文献综述为性别、男性气质、足球、暴力和性关系的交叉提供了理论、历史和社会背景。利用理论和背景框架,对深入访谈和焦点小组的定性数据进行了分析,以阐明男性角色的转变、矛盾和冲突。研究结果凸显了年轻男性改变危险、规范行为的过程是一个涉及男性与女性和其他男性关系的协商过程。
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引用次数: 0
Achievement of interventions on HIV infection prevention among migrants in China: A meta-analysis. 中国流动人口预防艾滋病感染干预措施的成果:荟萃分析。
IF 1.1 4区 医学 Q2 Social Sciences Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1451773
Rui Zhang, Ling Chen, Ya Deng Cui, Ge Li

In China, migrants with acquired immunodeficiency syndrome (AIDS) have become a serious problem in the field of AIDS prevention. This study aimed to evaluate the efficacy of interventions for human immunodeficiency virus (HIV) infection prevention for migrants in China and to identify factors associated with intervention efficacy. A computerized literature search of the Chinese National Knowledge Infrastructure, Wan Fang, and PubMed databases was conducted to collect related articles published in China. Only self-control intervention studies or studies containing sections regarding self-control interventions wherein the method of intervention was health education were included. Rev Manager 5.3 software was used to analyze the intervention effects in terms of knowledge, attitude, and behavior indexes. Relative to pre-intervention, the HIV interventions showed statistically significant efficacy in terms of sexual transmission of HIV, condom use for HIV prevention, change in attitude towards HIV/AIDS patients, incidence of commercial sex behavior, and recent condoms use during sex (P < .01). Moreover, the baseline rate of migrants, intervention time, peer education, region, and education background were factors influencing the efficacy of the intervention. Significant improvement in terms of knowledge of sexual transmission of HIV and attitudes and behaviors among migrants was observed; however, based on the findings of previous studies, the interventions should be customized for different people from different districts in China. Further research is needed to evaluate subgroups of migrants in China according to their baseline characteristics.

在中国,获得性免疫缺陷综合征(艾滋病)移民已成为艾滋病预防领域的一个严重问题。本研究旨在评估中国流动人口预防人类免疫缺陷病毒(HIV)感染干预措施的效果,并确定与干预效果相关的因素。研究人员利用计算机在中国知网、万方数据库和PubMed数据库中进行文献检索,收集在中国发表的相关文章。仅纳入自我控制干预研究或包含自我控制干预部分的研究,其中干预方法为健康教育。使用Rev Manager 5.3软件从知识、态度和行为指标分析干预效果。与干预前相比,艾滋病干预措施在艾滋病性传播、使用安全套预防艾滋病、改变对艾滋病患者的态度、商业性行为发生率以及最近在性行为中使用安全套等方面的效果均有统计学意义(P<0.05)。
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引用次数: 0
Effects of adolescent exposure to behaviour change interventions on their HIV risk reduction in Northern Malawi: a situation analysis. 马拉维北部青少年接触行为改变干预措施对其艾滋病毒风险降低的影响:一项情况分析。
IF 1.1 4区 医学 Q2 Social Sciences Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1529612
M Mwale, A S Muula

Understanding adolescents' translation of HIV and AIDS-related behaviour change interventions (BCI) knowledge and skills into expected behavioural outcomes helps us appreciate behaviour change dynamics among young people and informs evidence-based programming. We explored the effects of adolescents' exposure to BCI on their HIV risk reduction in selected schools in Nkhatabay and Mzimba districts and Mzuzu city in Northern Malawi. The study used questionnaires as instruments. Data were collected between January and April 2017. Adolescent boys and girls [n = 552], ages 11-19 were randomly sampled to participate. Data analysis was through multiple regression and content analysis. Respondents included 324 female [58.7%] and 228 male [41.3%]. Multiple regression analysis indicated that exposure to BCI did not affect risk reduction in the study area. The best stepwise model isolated sexual experience ([Beta = .727, p = .0001, p < .05]) as having the strongest correlation with the dependent variable - risk reduction. BCI exposure was stepwise excluded ([Beta = -.082, p = .053, p > .05]). There was therefore no evidence against the null hypothesis of no relationship between adolescent exposure to BCI and their HIV risk reduction. Overall there was limited BCI knowledge and skills translation to behavioural risk reduction. The study points to the need to evaluate and redesign adolescent BCI in line with current behavioural dynamics among young people in Malawi. The findings have been used to inform the design and programming of a model to be tested for feasibility through a quasi-experiment in the second phase of our project.

了解青少年将艾滋病毒和艾滋病相关的行为改变干预(BCI)知识和技能转化为预期的行为结果,有助于我们了解年轻人的行为改变动态,并为循证规划提供信息。我们在马拉维北部的Nkhatabay和Mzimba地区以及Mzuzu市的选定学校探讨了青少年接触脑机接口对降低其艾滋病毒风险的影响。这项研究使用问卷作为工具。数据收集于2017年1月至4月。随机抽取11-19岁的青春期男女[n = 552]参与研究。数据分析采用多元回归和内容分析。其中女性324人(58.7%),男性228人(41.3%)。多元回归分析表明,暴露于脑机损伤不影响研究区域的风险降低。最佳逐步模型分离性经验([Beta =。727, p =。0001, p .05])。因此,没有证据反对“青少年接触脑机脑损伤与其艾滋病毒风险降低之间没有关系”的零假设。总体而言,脑机接口知识和技能转化为减少行为风险的能力有限。该研究指出,需要根据马拉维年轻人目前的行为动态来评估和重新设计青少年脑机接口。研究结果已被用于通知模型的设计和编程,该模型将通过我们项目第二阶段的准实验进行可行性测试。
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引用次数: 11
Understanding the role played by parents, culture and the school curriculum in socializing young women on sexual health issues in rural South African communities. 了解父母、文化和学校课程在南非农村社区年轻女性性健康问题社会化方面发挥的作用。
IF 1.1 4区 医学 Q2 Social Sciences Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1455603
Feziwe Mpondo, Robert A C Ruiter, Dilana Schaafsma, Bart van den Borne, Priscilla S Reddy

Background: the decline in South Africa's HIV infection rates especially among young women is encouraging. However, studies show that the 15-24-year-old cohort remains vulnerable. As they still report early sexual debut, being involved in sexual partnerships with older men as well as having unprotected sex. These risky sexual behaviors may be linked to factors such as the parent-child sexual health communication and the timing of the first talk. The quality of sexual health information received in school may also be important for enhancing healthier sexual behaviors.

Aims and objectives: to investigate the what, when and how sexual health communication occurs in rural South African families and to determine whether such communication patterns have changed over time. We also wanted to get an in-depth understanding of the roles played by culture, sexual health education and peers in the socialization of young women on sexual matters.

Methods: a purposive sample of (n = 55) women who were 18-35 years old was selected and interviewed in focus group discussions (FGDs).

Results: the FGD findings show that parent-child communication on sexual matters in rural communities is limited to messages that warn against pregnancy. It is also laden with cultural idioms that are not well explained. The school sexual health curriculum also fails to adequately equip adolescents to make informed decisions regarding sexual matters. All this seems to leave room for reception of misguided information from peers.

Conclusions: findings highlight a need for designing interventions that can create awareness for parents on the current developmental needs and sexual behavior of adolescents. For adolescents programs would need to focus on providing skills on personal responsibility, and how to change behavior to enhance sexual health.

背景:南非艾滋病毒感染率,尤其是年轻女性感染率的下降令人鼓舞。然而,研究表明,15-24 岁的人群仍然很脆弱。因为她们仍然表示初次性行为过早、与年长男性发生性关系以及发生无保护措施的性行为。这些危险的性行为可能与父母与子女之间的性健康交流以及第一次谈话的时间等因素有关。目的和目标:调查南非农村家庭中性健康交流的内容、时间和方式,并确定这种交流模式是否随着时间的推移而发生变化。我们还希望深入了解文化、性健康教育和同伴在年轻女性性问题社会化过程中扮演的角色。方法:我们有目的性地抽取了(n = 55)名 18-35 岁的女性样本,并通过焦点小组讨论(FGDs)对她们进行了访谈。结果:FGDs 的结果显示,农村社区亲子间关于性问题的交流仅限于警告不要怀孕的信息。此外,这些信息还带有文化习语,没有得到很好的解释。学校的性健康课程也未能充分帮助青少年就性问题做出明智的决定。结论:研究结果表明,有必要设计一些干预措施,让父母了解青少年当前的发展需求和性行为。针对青少年的计划需要侧重于提供个人责任方面的技能,以及如何改变行为以增强性健康。
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引用次数: 0
Health-related quality of life and associated factors in adults living with HIV in Rwanda. 卢旺达成人艾滋病毒感染者的健康相关生活质量及相关因素。
IF 1.1 4区 医学 Q2 Social Sciences Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1520144
Juvenal Biraguma, Eugene Mutimura, José M Frantz

In Rwanda, as in other sub-Saharan African (SSA) countries, life expectancy of people living with HIV (PLWH) has increased dramatically as a result of combined antiretroviral therapy (cART). People living with HIV can now live longer but with increasing rates of non-communicable diseases (NCDs). Thus, prevention of NCD comorbidities in PWLHI is crucial to maintain and gain health-related benefits and to maximise the health-related quality of life (HRQOL) in the long-term management of PLWH. This study determines the association between physical and mental health-related dimensions of quality of life (QOL) with behavioural and biological risk factors, after controlling socio-demographic and HIV-related factors in adults living with HIV in Rwanda. A cross-sectional study using the WHO STEPwise approach and Kinyarwanda version of the MOS-HIV Health Survey, risk factors for NCDs and HRQOL were analysed for 794 PLWH, both HIV+ on ART and ART-naïve. Multiple regression analysis was used to examine the relationship between CMD risk factors and physical health and mental health summary scores. A total of 794 participants were interviewed. The mean age of the sample was 37.9 (±10.8) years and the majority of the participants were women (n = 513; 64.6%). About 16.2% reported daily smoking, 31.4% reported harmful alcohol use and 95% reported insufficient consumption of vegetables and fruits while 26.1% reported being physically inactive. 18.4% were overweight 43.4% had abdominal obesity, i.e. waist-hip-ratio (WHR) ≥0.95 in males and 0.85 in females. High blood pressure (HBP), i.e. systolic blood pressure (SBP) of ≥140 mmHg, or diastolic blood pressure (DBP) ≥90 mmHg was 24.4%. The results reveal that mean physical health summary and mental health summary score values were 63.96 ± 11.68 and 53.43 ± 10.89, respectively. While participants indicated that tobacco users and those who had abdominal obesity reported poor mental HRQOL, physical inactivity and hypertension have a negative impact on physical HRQOL. In addition, certain socio-demographic and HIV-related variables - specifically being unmarried, lack of HIV disclosure and low CD4 count (less 350 cell counts /mm3) - were associated with significantly lower mental and physical dimensions of quality of life. The results of this study reveal that behavioural and biological risk factors for NCDs were significantly associated with a lower HRQOL. These research findings also suggest that the assessment of the association between behavioural and biological risk factors for NCDs and a HRQOL provides opportunities for targeted counselling and secondary prevention efforts, so that health care providers can implement strategies that have a significant impact on the HRQOL.

在卢旺达,与其他撒哈拉以南非洲国家一样,由于抗逆转录病毒联合治疗,艾滋病毒感染者的预期寿命大幅增加。艾滋病毒感染者现在可以活得更长,但非传染性疾病的发病率也在上升。因此,在PLWH的长期管理中,预防非传染性疾病合并症对于维持和获得与健康相关的益处以及最大限度地提高与健康相关的生活质量(HRQOL)至关重要。本研究在控制卢旺达艾滋病毒感染者的社会人口统计学和艾滋病毒相关因素后,确定了生活质量(QOL)的身心健康相关维度与行为和生物学风险因素之间的关联。采用世卫组织逐步方法和卢旺达版的艾滋病毒健康调查的横断面研究,分析了794名艾滋病毒+抗逆转录病毒治疗和ART-naïve艾滋病毒感染者的非传染性疾病风险因素和HRQOL。采用多元回归分析检验CMD危险因素与身体健康和心理健康总结得分的关系。共有794名参与者接受了采访。样本的平均年龄为37.9(±10.8)岁,大多数参与者为女性(n = 513;64.6%)。约16.2%报告每天吸烟,31.4%报告有害饮酒,95%报告蔬菜和水果摄入不足,26.1%报告缺乏运动。18.4%超重,43.4%腹部肥胖,即腰臀比(WHR)男性≥0.95,女性≥0.85。高血压(HBP),即收缩压(SBP)≥140 mmHg或舒张压(DBP)≥90 mmHg占24.4%。结果显示,身体健康总结和心理健康总结平均分分别为63.96±11.68和53.43±10.89。虽然参与者表示,吸烟者和腹部肥胖的人报告的精神HRQOL较差,但缺乏运动和高血压对身体HRQOL有负面影响。此外,某些社会人口统计学和艾滋病毒相关变量-特别是未婚,缺乏艾滋病毒披露和低CD4计数(少于350细胞计数/mm3) -与生活质量的精神和身体维度显着降低相关。本研究结果显示,非传染性疾病的行为和生物学风险因素与较低的HRQOL显著相关。这些研究结果还表明,评估非传染性疾病的行为和生物学风险因素与HRQOL之间的关联,为有针对性的咨询和二级预防工作提供了机会,从而使卫生保健提供者能够实施对HRQOL有重大影响的战略。
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引用次数: 24
Determinants of disclosure and non-disclosure of HIV-positive status, by pregnant women in rural South Africa. 南非农村孕妇披露和不披露艾滋病毒阳性状况的决定因素。
IF 1.1 4区 医学 Q2 Social Sciences Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1529613
Shandir Ramlagan, Gladys Matseke, Violeta J Rodriguez, Deborah L Jones, Karl Peltzer, Robert A C Ruiter, Sibusiso Sifunda

Disclosure of HIV status remains one of the major challenges to the effectiveness of the prevention of mother to child transmission of HIV in rural areas in South Africa. This study aimed at assessing the determinants of HIV status disclosure among HIV infected pregnant women who have disclosed their HIV status to someone, as well as among those who have disclosed to their partners. Cross-sectional data was collected from 673 HIV sero-positive pregnant women receiving antenatal care services at 12 Community Health Centers in Mpumalanga province. Results indicated that over two-thirds (72.1%) disclosed their status to someone, while just over half (58.4%) disclosed to their partners. Multivariate analysis showed that both disclosure of ones HIV status to someone and to their male partners was significantly associated with increase in antiretroviral therapy (ART) adherence, the known HIV positive status of their partner, and male involvement during pregnancy. Participants who were diagnosed HIV positive during this current pregnancy were less likely to disclose their HIV status to someone. Non-disclosure during current pregnancy highlights a need for interventions that will encourage disclosure among HIV positive women, with a particular focus on those who are newly diagnosed. The findings also need to integrate male partner involvement and partner disclosure during pregnancy.

在南非农村地区,公开艾滋病毒感染状况仍然是有效预防艾滋病毒母婴传播的主要挑战之一。本研究旨在评估已向他人公开艾滋病毒感染状况的孕妇以及已向伴侣公开艾滋病毒感染状况的孕妇公开艾滋病毒感染状况的决定因素。我们从姆普马兰加省 12 个社区医疗中心接受产前保健服务的 673 名艾滋病毒血清反应呈阳性的孕妇中收集了横断面数据。结果显示,超过三分之二(72.1%)的孕妇向他人透露了自己的感染状况,而略高于一半(58.4%)的孕妇向伴侣透露了自己的感染状况。多变量分析表明,向他人和男性伴侣公开自己的艾滋病病毒感染状况与坚持抗逆转录病毒疗法(ART)、伴侣的已知艾滋病病毒呈阳性状况以及男性参与妊娠有很大关系。在本次怀孕期间被诊断为 HIV 阳性的参与者不太可能向他人透露自己的 HIV 感染状况。在当前怀孕期间不披露情况的情况突出表明,有必要采取干预措施,鼓励艾滋病毒呈阳性的妇女披露情况,尤其是那些新诊断出艾滋病毒呈阳性的妇女。研究结果还需要将男性伴侣的参与和伴侣在怀孕期间披露情况结合起来。
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引用次数: 0
Effect of a multicomponent behavioural PMTCT cluster randomised controlled trial on HIV stigma reduction among perinatal HIV positive women in Mpumalanga province, South Africa. 多组分行为PMTCT聚类随机对照试验对南非姆普马兰加省围产期艾滋病毒阳性妇女减少艾滋病毒耻辱感的影响
IF 1.1 4区 医学 Q2 Social Sciences Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1510787
Karl Peltzer, Suat Babayigit, Violeta J Rodriguez, Jenny Jean, Sibusiso Sifunda, Deborah L Jones

Background: We evaluate the impact a multicomponent, behavioural, prevention of mother to child transmission (PMTCT), cluster randomised controlled trial on HIV stigma reduction among perinatal HIV infected women in rural South Africa.

Methods: In a cluster randomised controlled trial, twelve community health centres (CHCs) in Mpumalanga Province, South Africa, were randomised; pregnant women living with HIV enrolled received either: A Standard Care (SC) condition plus time-equivalent attention-control on disease prevention (SC; 6 CHCs; n =357), or an Enhanced Intervention (EI) condition of SC PMTCT plus the 'Protect Your Family' intervention (EI; 6 CHCs; n =342). HIV-infected pregnant women in the SC attended four antenatal and two postnatal video sessions; those in the EI, four antenatal and two postnatal group PMTCT sessions, including stigma reduction, led by trained lay health workers. Maternal PMTCT, HIV knowledge and HIV related stigma were assessed. The impact of the EI was ascertained on stigma reduction (baseline, 12 months postnatally). A series of logistic regression and latent growth curve models were developed to test the impact of the intervention.

Results: In all, 699 women living with HIV were recruited during pregnancy (8-24 weeks), and assessments were completed prenatally at baseline and at 12 months (59.5%) postnatally. Baseline scores of overall HIV related stigma and the four scale factors (personalised stigma, disclosure concerns, negative self-image, and concern public attitudes) decreased at follow-up in the intervention group, while baseline scores of overall stigma and three scale factors (personalised stigma, negative self-image, and concern public attitudes) increased at follow-up in the control group. Using longitudinal analyses, Model 1, which included time-invariant predictors of stigma assessed over the two time periods of baseline and 12 months, increases in stigma from baseline to 12 months were associated with being unemployed, having been diagnosed with HIV before the current pregnancy, and alcohol use. In Model 2, which included time-varying predictors, lower stigma scores were associated with participation in the intervention, greater male partner involvement, and consistent condom use.

Conclusion: The enhanced PMTCT intervention, including stigma reduction, administered by trained lay health workers had a significant effect on the reduction of HIV related stigma.

Trial registration: clinicaltrials.gov: number NCT02085356.

背景:我们评估了一项多成分、行为、预防母婴传播(PMTCT)的聚类随机对照试验对南非农村围产期感染艾滋病毒的妇女减少艾滋病毒耻辱感的影响。方法:在一项聚类随机对照试验中,随机选取南非姆普马兰加省的12个社区卫生中心(CHCs);登记的感染艾滋病毒的孕妇接受以下两种治疗:标准护理(SC)条件加上与时间相当的疾病预防注意控制(SC);6 CHCs;n =357),或SC PMTCT的强化干预(EI)条件加上“保护你的家庭”干预(EI);6 CHCs;n = 342)。SC内感染艾滋病毒的孕妇参加了四次产前和两次产后录像会议;在EI中,由训练有素的非专业卫生工作者领导的四次产前和两次产后预防母婴传播小组会议,包括减少耻辱。对孕产妇预防母婴传播、艾滋病知识和艾滋病相关污名进行了评估。确定EI对柱头减少的影响(基线,出生后12个月)。我们建立了一系列的逻辑回归和潜在增长曲线模型来检验干预的影响。结果:总共招募了699名怀孕期间(8-24周)感染艾滋病毒的妇女,并在产前基线和产后12个月(59.5%)完成了评估。干预组总体HIV相关污名基线得分和4个量表因子(个体化污名、披露担忧、负面自我形象和关注公众态度)在随访时下降,对照组总体污名基线得分和3个量表因子(个体化污名、负面自我形象和关注公众态度)在随访时上升。使用纵向分析,模型1,其中包括在基线和12个月两个时间段内评估的耻辱感的时间不变预测因子,从基线到12个月的耻辱感增加与失业,在怀孕前被诊断患有艾滋病毒和饮酒有关。在模型2中,包括时变预测因子,较低的污名得分与参与干预,更多的男性伴侣参与和一致的安全套使用有关。结论:加强预防母婴传播干预,包括减少耻辱感,由训练有素的非专业卫生工作者管理,对减少艾滋病毒相关的耻辱感有显著效果。试验注册:clinicaltrials.gov:编号NCT02085356。
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引用次数: 16
Social and behavioural factors associated with risky sexual behaviours among university students in nine ASEAN countries: a multi-country cross-sectional study. 东盟九国大学生中与危险性行为相关的社会和行为因素:一项多国横断面研究。
IF 1.1 4区 医学 Q2 Social Sciences Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1503967
Siyan Yi, Vannarath Te, Supa Pengpid, Karl Peltzer

While university students are potential human resources, this population group is particularly involved in health risk behaviours. Preventing risky sexual behaviours among them would contribute to prevention of HIV, sexually transmitted infections (STIs), and unwanted pregnancies, which have posed a great burden on population health. This study was therefore conducted to identify social and behavioural factors associated with risky sexual behaviours among university students in nine ASEAN countries. A multi-country, cross-sectional study was conducted in 2015 among university students by a network of researchers in the selected countries. A convenient sampling method and stratified random sampling procedures were employed to select universities and students, respectively. A structured questionnaire was translated into national languages of the participating countries and used to collect data from the selected students in the classrooms. Using STATA, Chi-square test was used to test differences in proportions, and multinomial logistic regression analyses were performed to obtain relative risk ratios and 95% confidence intervals. Multivariate logistic regression analysis was performed with to identify independent social and behavioural factors associated with non-condom use at last sexual intercourse. In total, 8,836 students with a mean age of 20.6 (SD = 2.0) participated in the study. Most of them (98.5%) were unmarried. In all countries, male students were significantly more likely to have two or more sexual partners in the past 12 months compared to female students (4.8% vs. 1.1%, p < 0.001). Female students were significantly more likely to report unprotected sex compared to male students (50.5% vs. 58.8%, p = 0.01). Results of multivariable logistic regression analyses showed that students who reported having two or more partners in the past 12 months were significantly more likely to be male, be aged between 20-30, be current tobacco smokers, be binge drinkers, have severe depressive symptoms, and have been in a physical fight in the past 12 months, compared to students who reported having less than two sexual partners in the past 12 months. Health intervention programmes to prevent and control STIs, especially HIV infection, should focus on university students having the social and behavioural characteristics that are associated with risky sexual behaviours.

虽然大学生是潜在的人力资源,但这一群体的健康风险行为特别多。预防大学生的危险性行为将有助于预防艾滋病、性传播感染(STI)和意外怀孕,这些疾病已对人口健康造成了沉重负担。因此,本研究旨在确定与东盟九国大学生危险性行为相关的社会和行为因素。由选定国家的研究人员组成的网络于 2015 年在大学生中开展了一项多国横断面研究。研究分别采用了方便抽样法和分层随机抽样程序来选择大学和学生。结构化问卷被翻译成参与国的本国语言,用于在课堂上向被选中的学生收集数据。采用 STATA 方法,利用卡方检验(Chi-square test)检验比例差异,并进行多项式逻辑回归分析,以得出相对风险比和 95% 的置信区间。此外,还进行了多变量逻辑回归分析,以确定与最后一次性交时使用非避孕套相关的独立社会和行为因素。共有 8 836 名学生参与了研究,平均年龄为 20.6 岁(SD = 2.0)。其中大部分学生(98.5%)未婚。在所有国家中,与女生相比,男生在过去 12 个月中有两个或两个以上性伴侣的可能性明显更高(4.8% 对 1.1%,P<0.05)。
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引用次数: 0
'Why would you promote something that is less percent safer than a condom?': Perspectives on partially effective HIV prevention technologies among key populations in South Africa. 为什么要推广安全系数低于安全套的东西?南非重点人群对部分有效艾滋病预防技术的看法。
IF 1.1 4区 医学 Q2 Social Sciences Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1536561
Clara Rubincam, Peter A Newman, Millicent Atujuna, Linda-Gail Bekker

New biomedical prevention technologies (NPTs) for HIV, including oral Pre-Exposure Prophylaxis, and vaginal and rectal microbicides and HIV vaccines in development, may contribute substantially to controlling the HIV epidemic. However, their effectiveness is contingent on product acceptability and adherence. We explored perceptions and understanding of partially effective NPTs with key populations in South African townships. From October 2013 to February 2014, we conducted six focus groups and 18 individual interviews with Xhosa-speaking adolescents (n = 14), adult men who have sex with men (MSM) (n = 15), and adult heterosexual men (n = 9) and women (n = 10), and eight key informant (KI) interviews with healthcare workers. Interviews/focus groups were transcribed and reviewed using a thematic approach and framework analysis. Overall, participants and KIs indicated scepticism about NPTs that were not 100% efficacious. Some participants equated not being 100% effective with not being completely safe, and thus not appropriate for dissemination. KIs expressed concerns that promoting partially effective NPTs would encourage substitution of a more effective with a less effective method or encourage risk compensation. Educational and social marketing interventions that address the benefits and appropriate use of partially effective NPTs, including education and support tailored for frontline service providers, are needed to prepare for successful NPT implementation in South Africa.

新的艾滋病毒生物医学预防技术(NPTs),包括口服暴露前预防、阴道和直肠杀菌剂以及正在开发的艾滋病毒疫苗,可能会大大有助于控制艾滋病毒的流行。然而,它们的有效性取决于产品的可接受性和依从性。我们与南非乡镇的重点人群探讨了他们对部分有效的 NPT 的看法和理解。从 2013 年 10 月到 2014 年 2 月,我们对讲科萨语的青少年(14 人)、成年男男性行为者(15 人)、成年异性恋男性(9 人)和女性(10 人)进行了 6 次焦点小组讨论和 18 次个别访谈,并对医疗工作者进行了 8 次关键信息提供者 (KI) 访谈。采用主题方法和框架分析对访谈/焦点小组进行了誊写和审查。总体而言,参与者和关键信息提供者对非 100% 有效的 NPT 持怀疑态度。一些参与者将非 100% 有效等同于非完全安全,因此不适合推广。知识产 权机构表示担心,推广部分有效的 NPT 会鼓励用效果较差的方法替代效果较好的方法,或鼓励风险补偿。需要采取教育和社会营销干预措施,宣传部分有效的 NPT 的益处和适当使用方法,包括针对一线服务提供者的教育和支持,为在南非成功实施 NPT 做好准备。
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引用次数: 0
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Sahara J-Journal of Social Aspects of Hiv-Aids
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