Lin Zhou, Zhengzhi Zhu, Hongbo Gao, Chunyu Wang, Muhammad Attique Khan, Mati Ullah, Siffat Ullah Khan
The prevalence of digestive system tumours (DST) poses a significant challenge in the global crusade against cancer. These neoplasms constitute 20% of all documented cancer diagnoses and contribute to 22.5% of cancer-related fatalities. The accurate diagnosis of DST is paramount for vigilant patient monitoring and the judicious selection of optimal treatments. Addressing this challenge, the authors introduce a novel methodology, denominated as the Multi-omics Graph Transformer Convolutional Network (MGTCN). This innovative approach aims to discern various DST tumour types and proficiently discern between early-late stage tumours, ensuring a high degree of accuracy. The MGTCN model incorporates the Graph Transformer Layer framework to meticulously transform the multi-omics adjacency matrix, thereby illuminating potential associations among diverse samples. A rigorous experimental evaluation was undertaken on the DST dataset from The Cancer Genome Atlas to scrutinise the efficacy of the MGTCN model. The outcomes unequivocally underscore the efficiency and precision of MGTCN in diagnosing diverse DST tumour types and successfully discriminating between early-late stage DST cases. The source code for this groundbreaking study is readily accessible for download at https://github.com/bigone1/MGTCN.
{"title":"Multi-omics graph convolutional networks for digestive system tumour classification and early-late stage diagnosis","authors":"Lin Zhou, Zhengzhi Zhu, Hongbo Gao, Chunyu Wang, Muhammad Attique Khan, Mati Ullah, Siffat Ullah Khan","doi":"10.1049/cit2.12395","DOIUrl":"10.1049/cit2.12395","url":null,"abstract":"<p>The prevalence of digestive system tumours (DST) poses a significant challenge in the global crusade against cancer. These neoplasms constitute 20% of all documented cancer diagnoses and contribute to 22.5% of cancer-related fatalities. The accurate diagnosis of DST is paramount for vigilant patient monitoring and the judicious selection of optimal treatments. Addressing this challenge, the authors introduce a novel methodology, denominated as the Multi-omics Graph Transformer Convolutional Network (MGTCN). This innovative approach aims to discern various DST tumour types and proficiently discern between early-late stage tumours, ensuring a high degree of accuracy. The MGTCN model incorporates the Graph Transformer Layer framework to meticulously transform the multi-omics adjacency matrix, thereby illuminating potential associations among diverse samples. A rigorous experimental evaluation was undertaken on the DST dataset from The Cancer Genome Atlas to scrutinise the efficacy of the MGTCN model. The outcomes unequivocally underscore the efficiency and precision of MGTCN in diagnosing diverse DST tumour types and successfully discriminating between early-late stage DST cases. The source code for this groundbreaking study is readily accessible for download at https://github.com/bigone1/MGTCN.</p>","PeriodicalId":46211,"journal":{"name":"CAAI Transactions on Intelligence Technology","volume":"9 6","pages":"1572-1586"},"PeriodicalIF":7.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/cit2.12395","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143247961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Virtual reality (VR) technology revitalises rehabilitation training by creating rich, interactive virtual rehabilitation scenes and tasks that deeply engage patients. Robotics with immersive VR environments have the potential to significantly enhance the sense of immersion for patients during training. This paper proposes a rehabilitation robot system. The system integrates a VR environment, the exoskeleton entity, and research on rehabilitation assessment metrics derived from surface electromyographic signal (sEMG). Employing more realistic and engaging virtual stimuli, this method guides patients to actively participate, thereby enhancing the effectiveness of neural connection reconstruction—an essential aspect of rehabilitation. Furthermore, this study introduces a muscle activation model that merges linear and non-linear states of muscle, avoiding the impact of non-linear shape factors on model accuracy present in traditional models. A muscle strength assessment model based on optimised generalised regression (WOA-GRNN) is also proposed, with a root mean square error of 0.017,347 and a mean absolute percentage error of 1.2461%, serving as critical assessment indicators for the effectiveness of rehabilitation. Finally, the system is preliminarily applied in human movement experiments, validating the practicality and potential effectiveness of VR-centred rehabilitation strategies in medical recovery.
{"title":"Rehabilitation exoskeleton system with bidirectional virtual reality feedback training strategy","authors":"Yongsheng Gao, Guodong Lang, Chenxiao Zhang, Rui Wu, Yanhe Zhu, Yu Zhao, Jie Zhao","doi":"10.1049/cit2.12391","DOIUrl":"10.1049/cit2.12391","url":null,"abstract":"<p>Virtual reality (VR) technology revitalises rehabilitation training by creating rich, interactive virtual rehabilitation scenes and tasks that deeply engage patients. Robotics with immersive VR environments have the potential to significantly enhance the sense of immersion for patients during training. This paper proposes a rehabilitation robot system. The system integrates a VR environment, the exoskeleton entity, and research on rehabilitation assessment metrics derived from surface electromyographic signal (sEMG). Employing more realistic and engaging virtual stimuli, this method guides patients to actively participate, thereby enhancing the effectiveness of neural connection reconstruction—an essential aspect of rehabilitation. Furthermore, this study introduces a muscle activation model that merges linear and non-linear states of muscle, avoiding the impact of non-linear shape factors on model accuracy present in traditional models. A muscle strength assessment model based on optimised generalised regression (WOA-GRNN) is also proposed, with a root mean square error of 0.017,347 and a mean absolute percentage error of 1.2461%, serving as critical assessment indicators for the effectiveness of rehabilitation. Finally, the system is preliminarily applied in human movement experiments, validating the practicality and potential effectiveness of VR-centred rehabilitation strategies in medical recovery.</p>","PeriodicalId":46211,"journal":{"name":"CAAI Transactions on Intelligence Technology","volume":"10 3","pages":"728-737"},"PeriodicalIF":7.3,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/cit2.12391","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jinge Shi, Yi Chen, Ali Asghar Heidari, Zhennao Cai, Huiling Chen, Guoxi Liang
The Runge–Kutta optimiser (RUN) algorithm, renowned for its powerful optimisation capabilities, faces challenges in dealing with increasing complexity in real-world problems. Specifically, it shows deficiencies in terms of limited local exploration capabilities and less precise solutions. Therefore, this research aims to integrate the topological search (TS) mechanism with the gradient search rule (GSR) into the framework of RUN, introducing an enhanced algorithm called TGRUN to improve the performance of the original algorithm. The TS mechanism employs a circular topological scheme to conduct a thorough exploration of solution regions surrounding each solution, enabling a careful examination of valuable solution areas and enhancing the algorithm’s effectiveness in local exploration. To prevent the algorithm from becoming trapped in local optima, the GSR also integrates gradient descent principles to direct the algorithm in a wider investigation of the global solution space. This study conducted a serious of experiments on the IEEE CEC2017 comprehensive benchmark function to assess the enhanced effectiveness of TGRUN. Additionally, the evaluation includes real-world engineering design and feature selection problems serving as an additional test for assessing the optimisation capabilities of the algorithm. The validation outcomes indicate a significant improvement in the optimisation capabilities and solution accuracy of TGRUN.
{"title":"Topological search and gradient descent boosted Runge–Kutta optimiser with application to engineering design and feature selection","authors":"Jinge Shi, Yi Chen, Ali Asghar Heidari, Zhennao Cai, Huiling Chen, Guoxi Liang","doi":"10.1049/cit2.12387","DOIUrl":"10.1049/cit2.12387","url":null,"abstract":"<p>The Runge–Kutta optimiser (RUN) algorithm, renowned for its powerful optimisation capabilities, faces challenges in dealing with increasing complexity in real-world problems. Specifically, it shows deficiencies in terms of limited local exploration capabilities and less precise solutions. Therefore, this research aims to integrate the topological search (TS) mechanism with the gradient search rule (GSR) into the framework of RUN, introducing an enhanced algorithm called TGRUN to improve the performance of the original algorithm. The TS mechanism employs a circular topological scheme to conduct a thorough exploration of solution regions surrounding each solution, enabling a careful examination of valuable solution areas and enhancing the algorithm’s effectiveness in local exploration. To prevent the algorithm from becoming trapped in local optima, the GSR also integrates gradient descent principles to direct the algorithm in a wider investigation of the global solution space. This study conducted a serious of experiments on the IEEE CEC2017 comprehensive benchmark function to assess the enhanced effectiveness of TGRUN. Additionally, the evaluation includes real-world engineering design and feature selection problems serving as an additional test for assessing the optimisation capabilities of the algorithm. The validation outcomes indicate a significant improvement in the optimisation capabilities and solution accuracy of TGRUN.</p>","PeriodicalId":46211,"journal":{"name":"CAAI Transactions on Intelligence Technology","volume":"10 2","pages":"557-614"},"PeriodicalIF":7.3,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1049/cit2.12387","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143856758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}