Pub Date : 2024-11-19DOI: 10.47626/2237-6089-2024-0927
Mariana Paim Santos, Bibiana Bolten Lucion Loreto, Lisia von Diemen, Pedro Domingues Goi
Introduction: Clinical staging is widely applied in various fields of Medicine. Staging makes it possible to constitute early diagnoses and interventions, improving prognosis and preventing disease progression. In relation to Alcohol Use Disorder (AUD), staging is still an underdeveloped subject in the scientific literature. The treatment of AUD is effective for a minority of patients, requiring more targeted interventions individually. This study aims to propose a staging model for AUD that establishes key factors related to the progression of the disorder.
Method: Non-systematic review of the literature on Pubmed/Medline database focusing on articles about AUD and that present a stratified classification and treatment outcomes for that subpopulation through the progression of the disease.
Results: The model proposed includes stages 0 (latent), I A, I B, II A, II B, III A, III B and IV.
Discussion: This study can be used as a basis for a myriad of other reviews with the aim of validating a staging model in AUD. We recommend a systematic review study to validate the model suggested in this study and correlate clinical aspects with neurobiological aspects and the effectiveness of certain treatments.
Conclusion: This work shows that, based on the stratified classification of response to treatment, it is possible to suggest a staging model for AUD. Furthermore, the stages can be subdivided based on different clinical characteristics, risk factors, prognosis and management.
简介临床分期被广泛应用于医学的各个领域。分期使早期诊断和干预成为可能,从而改善预后并防止疾病恶化。就酒精使用障碍(AUD)而言,分期在科学文献中仍是一个发展不足的课题。AUD 的治疗对少数患者有效,需要更有针对性的个体干预。本研究旨在为 AUD 提出一个分期模型,以确定与该疾病进展相关的关键因素:方法:对Pubmed/Medline数据库中的文献进行非系统性回顾,重点关注有关AUD的文章,这些文章通过疾病的进展对该亚人群进行了分层分类并提供了治疗结果:提出的模型包括 0 期(潜伏期)、I A 期、I B 期、II A 期、II B 期、III A 期、III B 期和 IV 期:讨论:这项研究可作为大量其他审查的基础,目的是验证 AUD 的分期模型。我们建议开展一项系统性综述研究,以验证本研究提出的模型,并将临床方面与神经生物学方面以及某些治疗方法的有效性联系起来:这项工作表明,根据对治疗反应的分层分类,可以提出 AUD 的分期模型。此外,还可根据不同的临床特征、风险因素、预后和管理对分期进行细分。
{"title":"Clinical Staging of Alcohol Use Disorder: Proposal of a New Stratified Approach.","authors":"Mariana Paim Santos, Bibiana Bolten Lucion Loreto, Lisia von Diemen, Pedro Domingues Goi","doi":"10.47626/2237-6089-2024-0927","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0927","url":null,"abstract":"<p><strong>Introduction: </strong>Clinical staging is widely applied in various fields of Medicine. Staging makes it possible to constitute early diagnoses and interventions, improving prognosis and preventing disease progression. In relation to Alcohol Use Disorder (AUD), staging is still an underdeveloped subject in the scientific literature. The treatment of AUD is effective for a minority of patients, requiring more targeted interventions individually. This study aims to propose a staging model for AUD that establishes key factors related to the progression of the disorder.</p><p><strong>Method: </strong>Non-systematic review of the literature on Pubmed/Medline database focusing on articles about AUD and that present a stratified classification and treatment outcomes for that subpopulation through the progression of the disease.</p><p><strong>Results: </strong>The model proposed includes stages 0 (latent), I A, I B, II A, II B, III A, III B and IV.</p><p><strong>Discussion: </strong>This study can be used as a basis for a myriad of other reviews with the aim of validating a staging model in AUD. We recommend a systematic review study to validate the model suggested in this study and correlate clinical aspects with neurobiological aspects and the effectiveness of certain treatments.</p><p><strong>Conclusion: </strong>This work shows that, based on the stratified classification of response to treatment, it is possible to suggest a staging model for AUD. Furthermore, the stages can be subdivided based on different clinical characteristics, risk factors, prognosis and management.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-04DOI: 10.47626/2237-6089-2024-0904
Karen Rodrigues Lima, Bárbara Isabela Amorim, Débora Ribeiro Orlando, Luciano José Pereira, Paula Midori Castelo, Eric Francelino Andrade
Introduction: Excessive smartphone use has been linked to mental health impairments and may potentially alter human behavior. These effects are particularly pronounced among young individuals, with university students being especially susceptible to the negative influences of smartphone use.
Methods: This observational, cross-sectional study was conducted in a sample of 781 Brazilian university students. We assessed socio-economic variables, smartphone addiction, depression, anxiety, stress outcomes, eating behavior, body image satisfaction, and self-reported physical activity. MANOVA and Chi-square tests were performed to compare continuous and categorical variables between genders. K-means clustering was used to identify participant profiles based on various self-reported variables, with differences between clusters validated using the Z-test and the silhouette coefficient.
Results: Three clusters were identified. Cluster 1 featured participants with a significant disparity between their perceived and desired body image, higher scores on eating disorders, smartphone addiction, and mental health questionnaires, and lower engagement in physical exercise. Cluster 2 consisted of older participants who scored lower on smartphone addiction and mental health with a higher body mass index. Cluster 3 included younger participants with a smaller silhouette scale disparity, lower eating disorder scores, and lower body mass index. Smartphone addiction showed significant associations with eating disorders in overall eating disorders classification (X²=13.4; p<0.001), bulimic behavior (X²=20.0; p<0.001), and social pressure to eat (X²=4.3; p<0.001). It also negatively correlated with physical exercise (X²=5.7; p=0.017), but not with dieting concerns (X²=0.23; p=0.688).
Conclusion: Smartphone addiction is associated with eating disorders, stress, depression, anxiety, and lower levels of physical activity.
{"title":"Smartphone dependence predicts poorer mental health outcomes, eating behaviors, activity levels, and body image: A cluster analysis of Brazilian university students.","authors":"Karen Rodrigues Lima, Bárbara Isabela Amorim, Débora Ribeiro Orlando, Luciano José Pereira, Paula Midori Castelo, Eric Francelino Andrade","doi":"10.47626/2237-6089-2024-0904","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0904","url":null,"abstract":"<p><strong>Introduction: </strong>Excessive smartphone use has been linked to mental health impairments and may potentially alter human behavior. These effects are particularly pronounced among young individuals, with university students being especially susceptible to the negative influences of smartphone use.</p><p><strong>Methods: </strong>This observational, cross-sectional study was conducted in a sample of 781 Brazilian university students. We assessed socio-economic variables, smartphone addiction, depression, anxiety, stress outcomes, eating behavior, body image satisfaction, and self-reported physical activity. MANOVA and Chi-square tests were performed to compare continuous and categorical variables between genders. K-means clustering was used to identify participant profiles based on various self-reported variables, with differences between clusters validated using the Z-test and the silhouette coefficient.</p><p><strong>Results: </strong>Three clusters were identified. Cluster 1 featured participants with a significant disparity between their perceived and desired body image, higher scores on eating disorders, smartphone addiction, and mental health questionnaires, and lower engagement in physical exercise. Cluster 2 consisted of older participants who scored lower on smartphone addiction and mental health with a higher body mass index. Cluster 3 included younger participants with a smaller silhouette scale disparity, lower eating disorder scores, and lower body mass index. Smartphone addiction showed significant associations with eating disorders in overall eating disorders classification (X²=13.4; p<0.001), bulimic behavior (X²=20.0; p<0.001), and social pressure to eat (X²=4.3; p<0.001). It also negatively correlated with physical exercise (X²=5.7; p=0.017), but not with dieting concerns (X²=0.23; p=0.688).</p><p><strong>Conclusion: </strong>Smartphone addiction is associated with eating disorders, stress, depression, anxiety, and lower levels of physical activity.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-03DOI: 10.47626/2237-6089-2020-0094
Graccielle Cunha, Andre Zugman, Pedro Pan, Lais Fonseca, Rodrigo Bressan, Cristiane S Paula, Zila M Sanchez, Jair Mari, Ary Gadelha
Introduction: Current disease-specific models for prevention of mental disorders are challenged by the overlap of psychopathology, biological mechanisms, and risk factors. Moreover, mental disorders usually begin during childhood or adolescence, when symptoms fluctuate and are highly non-specific.
Discussion: We propose a staging model that integrates three domains - psychopathology, functional impairment and risk factors-, in which prevention is defined as actions to avoid stage progression, irrespective of diagnosis. Thus, preventive interventions should be broadened to include mental health promotion and strategies of risk reduction performed individually, at any stage, even for non-symptomatic subjects (before current at-risk definitions) currently exposed to risk factors.
Conclusions: The model features three innovations: a focus shift from disease conversion to stage progression, highlights functionality as an independent target, and acknowledgment of risk factors in the staging. The model must be validated before implementation.
{"title":"A transdiagnostic model to prevention in mental and behavioral disorders: a comprehensive review and delineation of a new proposal.","authors":"Graccielle Cunha, Andre Zugman, Pedro Pan, Lais Fonseca, Rodrigo Bressan, Cristiane S Paula, Zila M Sanchez, Jair Mari, Ary Gadelha","doi":"10.47626/2237-6089-2020-0094","DOIUrl":"https://doi.org/10.47626/2237-6089-2020-0094","url":null,"abstract":"<p><strong>Introduction: </strong>Current disease-specific models for prevention of mental disorders are challenged by the overlap of psychopathology, biological mechanisms, and risk factors. Moreover, mental disorders usually begin during childhood or adolescence, when symptoms fluctuate and are highly non-specific.</p><p><strong>Discussion: </strong>We propose a staging model that integrates three domains - psychopathology, functional impairment and risk factors-, in which prevention is defined as actions to avoid stage progression, irrespective of diagnosis. Thus, preventive interventions should be broadened to include mental health promotion and strategies of risk reduction performed individually, at any stage, even for non-symptomatic subjects (before current at-risk definitions) currently exposed to risk factors.</p><p><strong>Conclusions: </strong>The model features three innovations: a focus shift from disease conversion to stage progression, highlights functionality as an independent target, and acknowledgment of risk factors in the staging. The model must be validated before implementation.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-03DOI: 10.47626/2237-6089-2024-0882
Sarah Prates, Mariana Troesch, Rafaela Magalhães-Britto, Caroline Dallalana, Paula Studart-Bottó, Gabriela Léda-Rêgo, Juliana Socorro-Casqueiro, Stella Sarmento, Ângela Miranda Scippa
Objective: Caregivers appear to experience mental health implications related to their role in supporting patients with bipolar disorder (BD). This study aimed to review literature assessing the presence of not only psychiatric symptoms but also mental disorders and personality disorders in caregivers of patients with BD.
Methodology: This is a narrative review. Articles were searched in some computerized databases, including PubMed, Embase, Web of Science, PsychINFO, Liliacs, and Scielo up to June 2024. Inclusion criteria comprised articles in any language, focusing on primary caregivers of BD patients, and quantitative studies evaluating the presence of mental disorder, personality disorder, or psychiatric symptoms in this caregiver group.
Results: The review encompassed 15 articles. Only two studies utilized appropriate diagnostic instruments for assessing mental disorder, and no article evaluated personality disorder. Prevalence of caregiver's psychiatric symptoms and mental disorder was found to be higher compared to the general population.
Conclusions: The lack of studies employing diagnostic assessment tools for mental disorder in these individuals may impede timely access to treatment, affecting both the caregiver's health and the course of patients with BD. This study provides an updated overview of research on caregivers of patients with BD, despite the limitation of not being a systematic review. Further studies employing diagnostic assessments on caregivers are essential to gain deeper insights into this critical topic.
{"title":"Diagnosis of Mental Disorders in Caregivers of Patients with Bipolar Disorder: A Gap in the Scientific Literature.","authors":"Sarah Prates, Mariana Troesch, Rafaela Magalhães-Britto, Caroline Dallalana, Paula Studart-Bottó, Gabriela Léda-Rêgo, Juliana Socorro-Casqueiro, Stella Sarmento, Ângela Miranda Scippa","doi":"10.47626/2237-6089-2024-0882","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0882","url":null,"abstract":"<p><strong>Objective: </strong>Caregivers appear to experience mental health implications related to their role in supporting patients with bipolar disorder (BD). This study aimed to review literature assessing the presence of not only psychiatric symptoms but also mental disorders and personality disorders in caregivers of patients with BD.</p><p><strong>Methodology: </strong>This is a narrative review. Articles were searched in some computerized databases, including PubMed, Embase, Web of Science, PsychINFO, Liliacs, and Scielo up to June 2024. Inclusion criteria comprised articles in any language, focusing on primary caregivers of BD patients, and quantitative studies evaluating the presence of mental disorder, personality disorder, or psychiatric symptoms in this caregiver group.</p><p><strong>Results: </strong>The review encompassed 15 articles. Only two studies utilized appropriate diagnostic instruments for assessing mental disorder, and no article evaluated personality disorder. Prevalence of caregiver's psychiatric symptoms and mental disorder was found to be higher compared to the general population.</p><p><strong>Conclusions: </strong>The lack of studies employing diagnostic assessment tools for mental disorder in these individuals may impede timely access to treatment, affecting both the caregiver's health and the course of patients with BD. This study provides an updated overview of research on caregivers of patients with BD, despite the limitation of not being a systematic review. Further studies employing diagnostic assessments on caregivers are essential to gain deeper insights into this critical topic.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-03DOI: 10.47626/2237-6089-2024-0926
Santiago Madeira Diefenthaeler, Alice Cacilhas, Marina Luiza Hartmann, Daniel Prates-Baldez, Simone Hauck
Objective: This study aimed to evaluate mental health factors in individuals affected by the floods in Rio Grande do Sul from May 10 to June 6, 2024.
Methods: A real-time survey was conducted with 1,552 participants. The Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and Acute Stress Disorder (ASD) symptom checklist were used to assess mental health outcomes. Sociodemographic factors, trauma exposure, rescue participation, and psychological support were evaluated. Statistical analyses included t-tests, ANOVA, linear regression, and MANCOVA.
Results: High rates of depressive and anxious symptoms were found, with over half of the individuals with moderate to severe symptoms reporting no prior history of these conditions. Participants directly affected by the floods, and those with close ones affected, had higher PHQ-9, GAD-7, and ASD scores compared to the unaffected group. Moreover, younger age, female sex, lower family income, participation in rescues, and unmet psychological support needs were correlated with worse mental health outcomes. Individuals who participated in rescues had significantly higher rates of suicide ideation. Notably, psychological support had the largest effect size in mitigating mental health symptoms, regardless of trauma exposure status, when controlled for age, sex, and income according to MANCOVA.
Conclusions: The findings highlight the critical role of psychological support in disaster response and the importance of community resilience. Real-time data collection during crises can inform targeted interventions, emphasizing the need for robust mental health services and community support networks. These efforts are essential to reduce long-term psychological morbidity and foster recovery in vulnerable populations.
{"title":"Assessing Mental Health During an Extreme Weather Event in Southern Brazil.","authors":"Santiago Madeira Diefenthaeler, Alice Cacilhas, Marina Luiza Hartmann, Daniel Prates-Baldez, Simone Hauck","doi":"10.47626/2237-6089-2024-0926","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0926","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate mental health factors in individuals affected by the floods in Rio Grande do Sul from May 10 to June 6, 2024.</p><p><strong>Methods: </strong>A real-time survey was conducted with 1,552 participants. The Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and Acute Stress Disorder (ASD) symptom checklist were used to assess mental health outcomes. Sociodemographic factors, trauma exposure, rescue participation, and psychological support were evaluated. Statistical analyses included t-tests, ANOVA, linear regression, and MANCOVA.</p><p><strong>Results: </strong>High rates of depressive and anxious symptoms were found, with over half of the individuals with moderate to severe symptoms reporting no prior history of these conditions. Participants directly affected by the floods, and those with close ones affected, had higher PHQ-9, GAD-7, and ASD scores compared to the unaffected group. Moreover, younger age, female sex, lower family income, participation in rescues, and unmet psychological support needs were correlated with worse mental health outcomes. Individuals who participated in rescues had significantly higher rates of suicide ideation. Notably, psychological support had the largest effect size in mitigating mental health symptoms, regardless of trauma exposure status, when controlled for age, sex, and income according to MANCOVA.</p><p><strong>Conclusions: </strong>The findings highlight the critical role of psychological support in disaster response and the importance of community resilience. Real-time data collection during crises can inform targeted interventions, emphasizing the need for robust mental health services and community support networks. These efforts are essential to reduce long-term psychological morbidity and foster recovery in vulnerable populations.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-22DOI: 10.47626/2237-6089-2024-0908
Helena Garcia Dos Santos, Aline Longoni, Jéssica Puchalski Trettim, Isabela Thurow Lemes, Júlia de Castro Menchaca, Cainá Correa do Amaral, Mariana Bonati de Matos, Luciana de Avila Quevedo, Fernanda Nedel, Gabriele Ghisleni, Diogo Onofre Souza, Ricardo Tavares Pinheiro, Adriano Martimbianco de Assis
Objective: Approximately 6 to 13% of women suffer from antenatal depression (AD) around the world. AD can lead to several health problems for mother-baby. Vitamin D is a molecule that appears to have great preventive/therapeutic potential against neuropsychiatric disorders. The present study aimed to analyze the association between deficiency of vitamin D and AD in pregnant women in a city in the south of Brazil (Pelotas, RS). We hypothesize that pregnant women with a positive AD diagnosis have deficient levels of 25-hydroxyvitamin D (25(OH)D).
Methods: This cross-sectional study was conducted in a cohort study (CEP/UCPEL 47807915.4.0000.5339). From this cohort, 180 pregnant women at up to 24 weeks gestation were selected (130 non-depressed and 50 depressed), and the diagnosis of depression was made using the MINI-Plus. Blood was collected and stored for the later analysis of vitamin D (25(OH)D) by chemiluminescence method. The SPSS program was used for data analysis, and p<0.05 was considered statistically significant.
Results: In our study, we showed a significant association between Major Depressive Episode current in the antenatal period and vitamin D deficiency (OR: 0.9; CI 95%: 0.9;1.0, p=0.003).
Conclusion: Our results demonstrate that vitamin D deficiency may be involved in major depressive disorder in the antenatal period, in this way it advised a follow-up of vitamin D levels in the pregnancy-puerperal cycle to minimize mental health problems in women and prevent developmental deficits in children.
目的:全世界约有 6% 至 13% 的妇女患有产前抑郁症(AD)。产前抑郁症可导致母婴出现多种健康问题。维生素 D 是一种对神经精神疾病具有巨大预防/治疗潜力的分子。本研究旨在分析巴西南部城市佩洛塔斯(Pelotas,RS)孕妇缺乏维生素 D 与抑郁症之间的关系。我们假设,被确诊患有注意力缺失症的孕妇体内缺乏 25- 羟维生素 D (25(OH)D):这项横断面研究是在一项队列研究(CEP/UCPEL 47807915.4.0000.5339)中进行的。从该队列中挑选了 180 名妊娠 24 周以内的孕妇(130 名非抑郁症孕妇和 50 名抑郁症孕妇),并使用 MINI-Plus 诊断抑郁症。采集并储存的血液用于日后通过化学发光法分析维生素 D (25(OH)D)。使用 SPSS 程序进行数据分析,并得出 pResults:我们的研究表明,产前重度抑郁发作与维生素 D 缺乏之间存在显著关联(OR:0.9;CI 95%:0.9;1.0,P=0.003):我们的研究结果表明,维生素 D 缺乏可能与产前重度抑郁症有关,因此建议在妊娠-产褥期对维生素 D 水平进行随访,以尽量减少妇女的心理健康问题,并预防儿童发育缺陷。
{"title":"Deficiency of vitamin D is associated with antenatal depression: A cross-sectional study.","authors":"Helena Garcia Dos Santos, Aline Longoni, Jéssica Puchalski Trettim, Isabela Thurow Lemes, Júlia de Castro Menchaca, Cainá Correa do Amaral, Mariana Bonati de Matos, Luciana de Avila Quevedo, Fernanda Nedel, Gabriele Ghisleni, Diogo Onofre Souza, Ricardo Tavares Pinheiro, Adriano Martimbianco de Assis","doi":"10.47626/2237-6089-2024-0908","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0908","url":null,"abstract":"<p><strong>Objective: </strong>Approximately 6 to 13% of women suffer from antenatal depression (AD) around the world. AD can lead to several health problems for mother-baby. Vitamin D is a molecule that appears to have great preventive/therapeutic potential against neuropsychiatric disorders. The present study aimed to analyze the association between deficiency of vitamin D and AD in pregnant women in a city in the south of Brazil (Pelotas, RS). We hypothesize that pregnant women with a positive AD diagnosis have deficient levels of 25-hydroxyvitamin D (25(OH)D).</p><p><strong>Methods: </strong>This cross-sectional study was conducted in a cohort study (CEP/UCPEL 47807915.4.0000.5339). From this cohort, 180 pregnant women at up to 24 weeks gestation were selected (130 non-depressed and 50 depressed), and the diagnosis of depression was made using the MINI-Plus. Blood was collected and stored for the later analysis of vitamin D (25(OH)D) by chemiluminescence method. The SPSS program was used for data analysis, and p<0.05 was considered statistically significant.</p><p><strong>Results: </strong>In our study, we showed a significant association between Major Depressive Episode current in the antenatal period and vitamin D deficiency (OR: 0.9; CI 95%: 0.9;1.0, p=0.003).</p><p><strong>Conclusion: </strong>Our results demonstrate that vitamin D deficiency may be involved in major depressive disorder in the antenatal period, in this way it advised a follow-up of vitamin D levels in the pregnancy-puerperal cycle to minimize mental health problems in women and prevent developmental deficits in children.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-21DOI: 10.47626/2237-6089-2024-0931
Larissa Junkes, Antonio E Nardi
{"title":"Perspectives on mental health amid the crisis of climate refugees.","authors":"Larissa Junkes, Antonio E Nardi","doi":"10.47626/2237-6089-2024-0931","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0931","url":null,"abstract":"","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-20DOI: 10.47626/2237-6089-2024-0981
Jair de Jesus Mari, Naomar Almeida-Filho, Flávio Kapczinski, Antonio E Nardi
The Brazilian Academy of Sciences commissioned a report on mental health to develop strategies for addressing mental health challenges in the post-pandemic world. These strategies should be evidence-based, culturally sensitive, resource-efficient, and promote equity, while being tailored to specific contexts. The report's proposals are meant for discussion among S20 participating Academies of Sciences, serving as a collection of ideas to influence global mental health policies, rather than mandatory guidelines. Key points raised by the expert task force are highlighted for consideration.
{"title":"The S20 Brazilian Mental Health Report.","authors":"Jair de Jesus Mari, Naomar Almeida-Filho, Flávio Kapczinski, Antonio E Nardi","doi":"10.47626/2237-6089-2024-0981","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0981","url":null,"abstract":"<p><p>The Brazilian Academy of Sciences commissioned a report on mental health to develop strategies for addressing mental health challenges in the post-pandemic world. These strategies should be evidence-based, culturally sensitive, resource-efficient, and promote equity, while being tailored to specific contexts. The report's proposals are meant for discussion among S20 participating Academies of Sciences, serving as a collection of ideas to influence global mental health policies, rather than mandatory guidelines. Key points raised by the expert task force are highlighted for consideration.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-25DOI: 10.47626/2237-6089-2024-0894
Marcela Carbajal-Tamez, Elizabeth Monday, João Quevedo
{"title":"Celebrating scientific curiosity: 75th anniversary of the unexpected way lithium revolutionized psychopharmacology.","authors":"Marcela Carbajal-Tamez, Elizabeth Monday, João Quevedo","doi":"10.47626/2237-6089-2024-0894","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0894","url":null,"abstract":"","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142356137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-25DOI: 10.47626/2237-6089-2024-0873
Maiara da Silva Martins, Victor Matheus Lopes Martinez, Thiago Lucchina Pinto, Luis Eduardo Wearick-Silva, Thiago Wendt Viola
Purpose: Life experiences that could either promote or attenuate depression have primarily been studied in adults. Therefore, we investigated the association between lifestyle factors and symptoms of depression in adolescents.
Design and setting: A cross-sectional study was carried out in Brazilians.
Subjects: Data from 93 individuals were analyzed out of the 150 invited participants (age 14.2±1.8, 67.74% girls).
Measures: Lifestyle habits (SMILE-C), physical activity and sitting time (IPAQ), as well as symptoms of depression (DASS-21) were evaluated.
Analysis: A network analysis was performed using the EBIC-LASSO model, with the expected influence as a centrality parameter.
Results: The lifestyle domains with the highest expected influence were diet and nutrition (1.423), walking (1.126) and Stress Management (1.015). The variables with the highest direct partial negative correlation with depression were social support (-0.307) and moderate-vigorous physical activity (-0.244), suggesting a bidirectional relationship between these variables with lower symptoms of depression.
Conclusion: Specific lifestyle areas such as social support, physical activity and nutrition appear to impact other healthy habits while reducing teen depressive symptoms.
{"title":"Symptoms of depression and lifestyle in adolescents: A network analysis.","authors":"Maiara da Silva Martins, Victor Matheus Lopes Martinez, Thiago Lucchina Pinto, Luis Eduardo Wearick-Silva, Thiago Wendt Viola","doi":"10.47626/2237-6089-2024-0873","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0873","url":null,"abstract":"<p><strong>Purpose: </strong>Life experiences that could either promote or attenuate depression have primarily been studied in adults. Therefore, we investigated the association between lifestyle factors and symptoms of depression in adolescents.</p><p><strong>Design and setting: </strong>A cross-sectional study was carried out in Brazilians.</p><p><strong>Subjects: </strong>Data from 93 individuals were analyzed out of the 150 invited participants (age 14.2±1.8, 67.74% girls).</p><p><strong>Measures: </strong>Lifestyle habits (SMILE-C), physical activity and sitting time (IPAQ), as well as symptoms of depression (DASS-21) were evaluated.</p><p><strong>Analysis: </strong>A network analysis was performed using the EBIC-LASSO model, with the expected influence as a centrality parameter.</p><p><strong>Results: </strong>The lifestyle domains with the highest expected influence were diet and nutrition (1.423), walking (1.126) and Stress Management (1.015). The variables with the highest direct partial negative correlation with depression were social support (-0.307) and moderate-vigorous physical activity (-0.244), suggesting a bidirectional relationship between these variables with lower symptoms of depression.</p><p><strong>Conclusion: </strong>Specific lifestyle areas such as social support, physical activity and nutrition appear to impact other healthy habits while reducing teen depressive symptoms.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142356140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}