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Issues in the design of studies for the economic evaluation of new atypical antipsychotics: the ESTO study 新型非典型抗精神病药物经济评价研究设计中的问题:ESTO研究
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 1998-12-04 DOI: 10.1002/(SICI)1099-176X(199803)1:1<15::AID-MHP2>3.0.CO;2-O
M.F. Drummond, M.R.J. Knapp, T.P. Burns, K.D. Miller, P. Shadwell
<p><b>Background</b>: Increasing attention is being focused on the costs of healthcare and the need for cost-effective treatments. Drugs for schizophrenia have not escaped this scrutiny, especially now that several new agents are available, with acquisition costs substantially higher than for established therapies. However, most of the existing evaluations of new drugs for schizophrenia have weak designs, either comparing health care costs before and after introduction of the new drug, or being based on modelling approaches incorporating numerous assumptions.</p><p><b>Aim of the Study</b>: The aim of the study was to discuss and resolve the key design issues in the planning of a prospective randomized trial to assess the socio-economic impact of a new atypical antipsychotic (quetiapine).</p><p><b>Methods</b>: Key methodological issues were identified and discussed in the context of the economic evaluation being planned. These were patient recruitment and entry criteria, selection of comparator drug, blinding of doctor and patient, range of socio-economic outcomes, length of follow-up and sample size.</p><p><b>Results</b>: The resulting economic evaluation, the ESTO study, was an international multi-centre randomized controlled trial, with concurrent data collection for a wide range of clinical, economic and quality of life outcomes. The trial had a pragmatic design, enrolling patients experiencing an acute exacerbation on existing therapy. In addition to the presenting exacerbation, patients must have had at least one hospitalization or documented evidence of exacerbation within the previous three years. On admission to the study, existing psychotic medication was withdrawn prior to randomization to quetiapine or haloperidol. Doses of both drugs were titrated up to an optional dose, with flexibility for additional increases if required.</p><p>Both patients and doctors were blinded to treatment allocations, on the grounds that, since quetiapine was still in development, unblinded assessments of efficacy would not be credible. Patients were followed for 1 year, irrespective of whether they withdrew from study medication.</p><p>A wide range of socio-economic outcomes was assessed, including costs falling on the healthcare sector, other agencies and the family. In addition data were collected on patients’ earnings and quality of life, measured by the Short-Form 36 health profile. Data were also collected on a range of clinical measures, such as the Positive and Negative Syndrome Scale (PANSS), the Clinical Global Impressions (CGI), the AIMS neurological rating scale and the neurological rating scale of Simpson and Angus. This was to assess whether changes in socio-economic end points were indeed matched by changes in the patient’s clinical condition.</p><p><b>Conclusions</b>: The design of studies such as ESTO is inevitably a compromise between control and pragmatism. For example, whilst blinding of doctor and patient may reduce potential bias, this
背景:人们越来越关注医疗保健成本和成本效益高的治疗需求。治疗精神分裂症的药物也未能逃脱审查,尤其是现在有了几种新的药物,其获取成本远高于现有疗法。然而,大多数现有的精神分裂症新药评估都有薄弱的设计,要么是比较新药推出前后的医疗保健成本,要么是基于包含许多假设的建模方法。研究目的:本研究的目的是讨论和解决一项前瞻性随机试验规划中的关键设计问题,以评估一种新型非典型抗精神病药物(喹硫平)的社会经济影响。方法:在计划的经济评估中确定和讨论关键方法学问题。这些是患者招募和进入标准、对照药物的选择、医生和患者的盲法、社会经济结果的范围、随访时间和样本量。结果:由此产生的经济评估,即ESTO研究,是一项国际多中心随机对照试验,同时收集了广泛的临床、经济和生活质量结果的数据。该试验采用了务实的设计,招募了在现有治疗中出现急性加重的患者。除了表现为恶化外,患者必须在前三年内至少有一次住院治疗或有恶化证据。在进入研究时,在随机分配给喹硫平或氟哌啶醇之前,停用现有的精神病药物。两种药物的剂量都被滴定到可选剂量,如果需要,可以灵活地增加剂量。患者和医生都对治疗分配视而不见,理由是由于喹硫平仍在开发中,对疗效的非盲评估是不可信的。患者被随访1年,无论他们是否退出研究药物。评估了广泛的社会经济结果,包括医疗保健部门、其他机构和家庭的成本下降。此外,还收集了关于患者收入和生活质量的数据,这些数据是通过Short Form 36健康档案来衡量的。还收集了一系列临床指标的数据,如阳性和阴性综合征量表(PANSS)、临床总体印象(CGI)、AIMS神经评分量表以及Simpson和Angus的神经评分量。这是为了评估社会经济终点的变化是否与患者临床状况的变化相匹配。结论:ESTO等研究的设计不可避免地是控制和实用主义之间的妥协。例如,虽然医生和患者的致盲可能会减少潜在的偏见,但由于使用了额外的假药物,这可能会导致依从性困难。尽管有这些妥协,ESTO的研究应该能对一种新的抗精神病药物的社会经济结果进行更可靠的评估,并得到了分析师和研究人员的广泛支持。它已经成为其他研究的模板,如果该方法成功,将对未来类似药物的评估产生影响。©1998 John Wiley&;有限公司。
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引用次数: 24
Physician knowledge, financial incentives and treatment decisions for depression 抑郁症的医生知识、经济激励和治疗决策
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 1998-12-04 DOI: 10.1002/(SICI)1099-176X(199807)1:2<89::AID-MHP12>3.0.CO;2-V
Roland Sturm, Kenneth B. Wells

Background: Two important policy levers to affect health care delivery are financing and informational interventions. Unfortunately, these two approaches have not been considered simultaneously and little is known about how their effects compare.

Aims of the Study: This paper estimates the relative role of financial incentives (prepaid versus fee for service) and provider information (perceived knowledge of antidepressant medications and skill in counseling for depression) on quality of care for less and more severely depressed patients and their health and cost outcomes.

Methods: We develop a theoretical model of provider behavior and estimate a reduced form using a multinomial probit model with heteroskedastic covariances. The likely effects of changing provider knowledge about depression treatment in primary care are then simulated and contrasted with the effects of a shift toward prepaid managed care as opposed to fee-for-service care. The empirical model is estimated using data from the Medical Outcomes Study.

Results: We conclude that financing and information have different effects and that their combination can achieve the conflicting goals of improved health outcomes and reduced direct treatment goals. Moreover, including family income as one important dimension of social cost suggests that the combination of informational interventions and a shift to prepaid care may dominate either one intervention in isolation from a social cost perspective. Specifically regarding information, we found that increasing provider knowledge could have the highly desirable effect of greater targeting of treatments to sicker patients while not raising overall treatment rates much—a treatment pattern that many hoped managed care could achieve, but for which there has been little evidence.

Conclusions: Our analysis illustrates the value of considering these widely different policy goals simultaneously. We learned that variation in physician knowledge generally had stronger associations with clinically relevant practice patterns for depression than did a complete change in financing strategy. The moderate change in perceived knowledge we simulated (not near the extremes of observed values of perceived knowledge) was associated with enough improvement in appropriateness of care to more than offset the reduction in appropriateness with a complete shift from fee-for-service to prepaid managed care.

Implications for Health Policy: The paper demonstrates the importance of considering different interventions simultaneously. Combining informational and financial interventions simultaneously can achieve better quality of care and reduce health care costs, something neither intervention can in isolation. © 1998 John Wiley & Sons, Ltd.

背景:影响医疗保健提供的两个重要政策杠杆是资金和信息干预。不幸的是,这两种方法没有被同时考虑,对它们的效果如何比较也知之甚少。研究目的:本文估计了经济激励(预付费与服务费)和提供者信息(抗抑郁药物的认知知识和抑郁症咨询技能)对轻度和重度抑郁症患者的护理质量及其健康和成本结果的相对作用。方法:我们开发了一个提供者行为的理论模型,并使用具有异方差的多项式概率模型来估计简化形式。然后,模拟提供者对初级保健中抑郁症治疗知识的改变可能产生的影响,并将其与向预付费管理护理而非收费服务护理转变的影响进行对比。经验模型是使用来自医学结果研究的数据进行估计的。结果:我们得出结论,资金和信息具有不同的效果,它们的结合可以实现改善健康结果和减少直接治疗目标这两个相互矛盾的目标。此外,将家庭收入作为社会成本的一个重要维度表明,从社会成本的角度来看,信息干预和向预付费护理的转变相结合可能会单独主导任何一种干预。特别是在信息方面,我们发现,增加提供者的知识可能会产生非常理想的效果,即更大程度地针对病情较重的患者进行治疗,同时不会大大提高总体治疗率——许多人希望管理性护理能够实现这种治疗模式,但几乎没有证据表明这一点。结论:我们的分析说明了同时考虑这些截然不同的政策目标的价值。我们了解到,与融资策略的完全改变相比,医生知识的变化通常与抑郁症的临床相关实践模式有更强的关联。我们模拟的感知知识的适度变化(不接近感知知识观察值的极端值)与护理适当性的足够改善有关,从按服务收费向预付费管理护理的完全转变远远抵消了适当性的降低。对卫生政策的影响:该文件证明了同时考虑不同干预措施的重要性。同时将信息和财政干预相结合可以实现更好的护理质量和降低医疗成本,而这两种干预都无法单独实现。©1998 John Wiley&;有限公司。
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引用次数: 6
Factors influencing informal care-giving 影响非正式护理的因素
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 1998-12-04 DOI: 10.1002/(SICI)1099-176X(199807)1:2<77::AID-MHP10>3.0.CO;2-5
Ann M. Holmes, Partha Deb
BACKGROUND: As downsizing of institutional care continues, patients discharged are likely to have more severe mental illnesses, and to have experienced longer tenures within institutions than patients who have been discharged in the past. As greater numbers of patients are removed from mental hospitals, the objective burden experienced by informal care-givers may increase, particularly if formal care levels are inadequate. AIMS OF THE STUDY: This paper documents who assumes informal care-giver roles, and the form such care-giving takes for patients discharged from a state hospital. Specifically, this paper identifies (i) what factors affect a person's decision to assume a care-giver role, including the participation of other network members in care-giving, (ii) what factors influence whether care-giving is provided in time or in direct purchase of care and (iii) how the patient's treatment location affects the decision of the network member to assume any care-giving role. DATA AND ANALYTICAL METHODS: Data for this paper are taken from a longitudinal study of the closure of a state mental hospital in central Indiana. Seventy-seven patients were asked to identify their community networks. Ninety-eight network members were surveyed about the informal care, both in time or through direct expenditures, they provided to these patients one year after discharge. Care-giving relationships were estimated using a multivariate probit model. Such a model estimates the extent to which the decision to provide care in either form depends on the care-giving activities assumed by other network members associated with a given patient, as well as the characteristics of individual patients and network members. RESULTS: Forty-one per cent of network members provided some level of informal care, with 13.3% providing some care in time, and 35.7% providing some care through direct expenditures. A positive relationship was found between participation in informal care-giving and the perception by the network member that patient needs were not being met by professionals. The decision to provide informal care was also found to be sensitive to the level of informal and formal care received by the patient. Care-giving in expense was found to be positively related to the care-giving decisions of other informal care-givers, but care-giving in time was not. Network members were more likely to provide care in time for patients who had been recently discharged to the community than for patients who remained in institutional settings. CONCLUSIONS: These results suggest the transfer of persons with severe mental illnesses from state hospitals to the community may shift the care burden between formal and informal providers. If this is the case, discharge criteria should include such factors as the community resources available to the patient. IMPLICATIONS FOR HEALTH CARE PROVISION AND USE: The responsiveness of network members to perceived unmet need bespeaks the importance of informa
背景:随着机构护理规模的不断缩小,出院的患者可能会患上更严重的精神疾病,并且在机构内的任期比过去出院的患者更长。随着越来越多的患者从精神病院出院,非正式护理人员所经历的客观负担可能会增加,特别是在正式护理水平不足的情况下。研究目的:本文记录了谁承担非正式的护理人员角色,以及从州立医院出院的患者的护理形式。具体而言,本文确定了(i)哪些因素影响一个人承担照顾者角色的决定,包括其他网络成员参与照顾,(ii)哪些因素影响护理是及时提供还是直接购买护理,以及(iii)患者的治疗地点如何影响网络成员承担任何护理角色的决定。数据和分析方法:本文的数据来自对印第安纳州中部一家州立精神病院关闭的纵向研究。77名患者被要求确定他们的社区网络。98名网络成员接受了关于他们在出院一年后为这些患者提供的非正规护理的调查,无论是及时还是通过直接支出。护理关系使用多变量probit模型进行估计。这种模型估计了以任何一种形式提供护理的决定在多大程度上取决于与给定患者相关的其他网络成员所承担的护理活动,以及个体患者和网络成员的特征。结果:41%的网络成员提供了一定程度的非正式护理,13.3%的成员及时提供了一些护理,35.7%的成员通过直接支出提供了一些服务。研究发现,参与非正式护理与网络成员认为专业人员没有满足患者需求之间存在积极关系。提供非正式护理的决定也被发现对患者接受的非正式和正式护理的水平很敏感。研究发现,费用上的护理与其他非正式护理人员的护理决策呈正相关,但时间上的护理则不然。与留在机构环境中的患者相比,网络成员更有可能为最近出院到社区的患者及时提供护理。结论:这些结果表明,将患有严重精神疾病的人从州立医院转移到社区可能会在正式和非正式提供者之间转移护理负担。如果是这种情况,出院标准应包括患者可获得的社区资源等因素。对医疗保健提供和使用的影响:当无法保证正式护理的连续性时,网络成员对感知到的未满足需求的反应表明了非正式护理的重要性。研究结果还表明,当患者从机构出院时,可能会有一些正式和非正式护理的替代。需要进一步分析,以确定网络成员对未满足需求的感知是否准确,以及如何使网络成员更好地适应患者实际经历的未满足需求。©1998 John Wiley&;有限公司。
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引用次数: 12
Interactions between use of and insurance for specialty ambulatory mental health services 专业门诊心理健康服务的使用和保险之间的相互作用
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 1998-12-04 DOI: 10.1002/(SICI)1099-176X(1998100)1:3<119::AID-MHP14>3.0.CO;2-2
Marc P. Freiman
<p><b>Background</b>: There is continuing interest in the effects of coinsurance rates on the use of ambulatory mental health services. Persons who expect to use mental health services may choose coverage with more generous mental health benefits, as such treatment may be expected to be a recurring activity. However, it may also be the case that if the expected need for such services is somehow reflected in lower perceived human capital in the labor market, then persons who have a higher probability of use may face a less generous set of health insurance options. These behaviors imply some simultaneity in the determinants of the coinsurance rate facing an individual and their mental health use.</p><p><b>Aim of the study</b>: To explore the joint determination of the use of and coinsurance for ambulatory mental health services, using non-experimental data for a nationally representative sample of the non-institutionalized who had employer-based health insurance in the United States.</p><p><b>Methods</b>: I estimate an instrument for the ambulatory mental health coinsurance rate. I then estimate two models of the demand for ambulatory mental health care as a function of the coinsurance rate for this type of care and other factors, one using the actual coinsurance rate and the other using the estimated instrument for the coinsurance rate.</p><p><b>Results</b>: In the instrumental equation, an index of the mental distress of the key worker most likely to be the policy-holder has no statistically significant effect on the worker’s coinsurance rate. However, a similar measure for other members of the worker’s family has a positive and statistically significant effect on the worker’s coinsurance rate. In the demand equations, neither the actual coinsurance rate nor its instrument has a statistically significant coefficient.</p><p><b>Discussion</b>: Having another family member who may need mental health care results in some effort to seek a health plan with a higher coinsurance rate for such services. While the mental health index for the key worker would motivate the same type of seeking behavior, a higher level for this index for the key worker might also be correlated with a lower level of perceived human capital in a prospective employer’s eyes, and this might result in a more restricted set of plan options for mental health care in the labor market. The absence of statistical significant for the coefficients of the actual coinsurance rate and its instrument also provides some limited but suggestive evidence of employer-side selection effects.</p><p><b>Limitations</b>: It was not possible to model the full complexity of health plans.</p><p><b>Conclusions</b>: The discussions of selection bias with regard to mental health insurance and service use should be expanded to include demand-side effects in the labor market, in addition to the supply-side effects on the part of workers that are often considered.</p><p><b>Implications for health care provisio
背景:人们继续关注共同保险费率对门诊精神卫生服务使用的影响。希望使用心理健康服务的人可以选择更慷慨的心理健康福利,因为这种治疗可能是一种经常性的活动。然而,也可能存在这样的情况:如果对此类服务的预期需求在某种程度上反映在劳动力市场中感知到的人力资本较低,那么使用概率较高的人可能会面临一套不那么慷慨的医疗保险选择。这些行为意味着个人面临的共同保险率及其心理健康使用的决定因素具有一定的同时性。本研究的目的:利用非实验数据,对美国拥有雇主健康保险的非机构化非机构化样本,探讨门诊心理健康服务的使用和共同保险的联合确定。方法:我估计了门诊心理健康共同保险率的工具。然后,我估计了两个动态心理健康护理需求模型,作为这类护理的共同保险费率和其他因素的函数,一个使用实际共同保险费率,另一个使用共同保险费率的估计工具。结果:在工具方程中,最有可能成为保单持有人的关键员工的精神痛苦指数对员工的共同保险率没有统计学上的显著影响。然而,针对工人家庭其他成员的类似措施对工人的共同保险率有积极且统计上显著的影响。在需求方程中,实际共保率及其工具都没有统计显著系数。讨论:有另一个可能需要心理健康护理的家庭成员会努力寻求一个对此类服务具有更高共同保险率的健康计划。虽然关键员工的心理健康指数会激发相同类型的寻求行为,但关键员工的这一指数水平越高,潜在雇主眼中感知的人力资本水平也可能越低,这可能会导致劳动力市场中心理健康护理的计划选择更加受限。实际共同保险率及其工具的系数缺乏统计学显著性,这也为雇主的选择效应提供了一些有限但有启发性的证据。局限性:不可能对健康计划的全部复杂性进行建模。结论:关于心理健康保险和服务使用方面的选择偏见的讨论应该扩大到包括劳动力市场的需求副作用,以及经常被考虑的工人的供应副作用。对医疗保健提供和使用的影响:可能很难确定医疗保险条款的变化对门诊精神卫生保健的影响。对健康政策制定的影响:在估计门诊精神卫生保健保险范围变化的影响时需要谨慎。发现自己的福利得到改善的人可能不会以预期的速度做出反应,因为最初的共同保险费率已经在一定程度上与预期的使用交织在一起。对进一步研究的启示:有必要对劳动力市场的选择效应范围及其对医疗保险的影响进行更多的分析。©1998 John Wiley&;有限公司。
{"title":"Interactions between use of and insurance for specialty ambulatory mental health services","authors":"Marc P. Freiman","doi":"10.1002/(SICI)1099-176X(1998100)1:3<119::AID-MHP14>3.0.CO;2-2","DOIUrl":"https://doi.org/10.1002/(SICI)1099-176X(1998100)1:3<119::AID-MHP14>3.0.CO;2-2","url":null,"abstract":"&lt;p&gt;&lt;b&gt;Background&lt;/b&gt;: There is continuing interest in the effects of coinsurance rates on the use of ambulatory mental health services. Persons who expect to use mental health services may choose coverage with more generous mental health benefits, as such treatment may be expected to be a recurring activity. However, it may also be the case that if the expected need for such services is somehow reflected in lower perceived human capital in the labor market, then persons who have a higher probability of use may face a less generous set of health insurance options. These behaviors imply some simultaneity in the determinants of the coinsurance rate facing an individual and their mental health use.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Aim of the study&lt;/b&gt;: To explore the joint determination of the use of and coinsurance for ambulatory mental health services, using non-experimental data for a nationally representative sample of the non-institutionalized who had employer-based health insurance in the United States.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Methods&lt;/b&gt;: I estimate an instrument for the ambulatory mental health coinsurance rate. I then estimate two models of the demand for ambulatory mental health care as a function of the coinsurance rate for this type of care and other factors, one using the actual coinsurance rate and the other using the estimated instrument for the coinsurance rate.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results&lt;/b&gt;: In the instrumental equation, an index of the mental distress of the key worker most likely to be the policy-holder has no statistically significant effect on the worker’s coinsurance rate. However, a similar measure for other members of the worker’s family has a positive and statistically significant effect on the worker’s coinsurance rate. In the demand equations, neither the actual coinsurance rate nor its instrument has a statistically significant coefficient.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Discussion&lt;/b&gt;: Having another family member who may need mental health care results in some effort to seek a health plan with a higher coinsurance rate for such services. While the mental health index for the key worker would motivate the same type of seeking behavior, a higher level for this index for the key worker might also be correlated with a lower level of perceived human capital in a prospective employer’s eyes, and this might result in a more restricted set of plan options for mental health care in the labor market. The absence of statistical significant for the coefficients of the actual coinsurance rate and its instrument also provides some limited but suggestive evidence of employer-side selection effects.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Limitations&lt;/b&gt;: It was not possible to model the full complexity of health plans.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions&lt;/b&gt;: The discussions of selection bias with regard to mental health insurance and service use should be expanded to include demand-side effects in the labor market, in addition to the supply-side effects on the part of workers that are often considered.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Implications for health care provisio","PeriodicalId":46381,"journal":{"name":"Journal of Mental Health Policy and Economics","volume":"1 3","pages":"119-127"},"PeriodicalIF":1.6,"publicationDate":"1998-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72132711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Mental health and substance abuse parity: a case study of Ohio’s state employee program 心理健康与药物滥用均等:俄亥俄州雇员计划的个案研究
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 1998-12-04 DOI: 10.1002/(SICI)1099-176X(1998100)1:3<129::AID-MHP16>3.0.CO;2-U
Roland Sturm, William Goldman, Joyce Mcculloch
BACKGROUND: In the United States, insurance benefits for treating alcohol, drug abuse and mental health (ADM) problems have been much more limited than medical care benefits. To change that situation, more than 30 states were considering legislation that requires equal benefits for ADM and medical care ("parity") in the past year. Uncertainty about the cost consequences of such proposed legislation remains a major stumbling block. There has been no information about the actual experience of implementing parity benefits under managed care or the effects on access to care and utilization. AIMS OF THE STUDY: Document the experience of the State of Ohio with adopting full parity for ADM care for its state employee program under managed care. Ohio provides an unusually long time series with seven years of managed behavioral health benefits, which allows us to study inflationary trends in a plan with unlimited ADM benefits. METHODS: Primarily a case study, we describe the implementation of the program and track utilization, and costs of ADM care from 1989 to 1997. We use a variety of administrative and claims data and reports provided by United Behavioral Health and the state of Ohio. The analysis of the utilization and cost effect of parity and managed care is pre-post, with a multiyear follow-up period. RESULTS: The switch from unmanaged indemnity care to managed carve-out care was followed by a 75% drop in inpatient days and a 40% drop in outpatient visits per 1000 members, despite the simultaneous increase in benefits. The subsequent years saw a continuous decline in inpatient days and an increased use of intermediate services, such as residential care and intensive outpatient care. The number of outpatient visits stabilized in the range of 500-550 visits per 1000. There was no indication that costs started to increase during the study period; instead, costs continued to decline. A somewhat different picture emerges when comparing utilization under HMOs with utilization under a carve-out with expanded benefits. In that case, the expansion of benefits led to a significant jump in outpatient utilization and intermediate services, while there was a small decrease in inpatient days. Insurance payments in 1996/1997 were almost identical to the estimated costs under HMOs in 1993. CONCLUSIONS: In contrast to the emerging inflation anxiety regarding overall health care costs, managed care can provide long-run cost containment for ADM care even when patient copayments are reduced and coverage limits are lifted. This may differentiate ADM care from medical care and reasons for this difference include the state of management techniques (more advanced for ADM care), complexity of treatments (much higher technology utilization in medical care) and demographic factors (medical, but not behavioral health, costs increase as the population ages). IMPLICATIONS FOR HEALTH POLICY: The experience of the state of Ohio demonstrates that parity level benefits for ADM care
背景:在美国,治疗酒精、药物滥用和心理健康(ADM)问题的保险福利比医疗福利要有限得多。为了改变这种情况,在过去的一年里,30多个州正在考虑立法,要求ADM和医疗保健享有同等福利(“公平”)。关于此类拟议立法的成本后果的不确定性仍然是一个主要障碍。没有关于在管理护理下实施平价福利的实际经验或对获得护理和利用的影响的信息。研究目的:记录俄亥俄州在管理护理下对其州雇员计划采用ADM护理完全平等的经验。俄亥俄州提供了一个异常长的时间序列,其中包含七年的管理行为健康福利,这使我们能够在一个具有无限ADM福利的计划中研究通货膨胀趋势。方法:首先通过案例研究,我们描述了1989年至1997年ADM护理计划的实施情况、使用情况和费用。我们使用了联合行为健康公司和俄亥俄州提供的各种行政和索赔数据和报告。对平价和管理护理的利用率和成本效应的分析是事前-事后的,有多年的随访期。结果:尽管福利同时增加,但从非管理赔偿护理向管理分拆护理的转变之后,每1000名会员的住院天数下降了75%,门诊就诊次数下降了40%。随后几年,住院天数持续下降,住院护理和门诊重症监护等中间服务的使用增加。门诊就诊次数稳定在每1000人中有500至550次就诊。没有迹象表明在研究期间费用开始增加;相反,成本持续下降。当将HMO的利用率与扩大收益的分拆下的利用率进行比较时,情况会有所不同。在这种情况下,福利的扩大导致门诊使用率和中间服务的大幅增加,而住院天数略有减少。1996/1997年的保险支付与1993年HMO的估计费用几乎相同。这可以将ADM护理与医疗护理区分开来,并且这种差异的原因包括管理技术的现状(对于ADM护理更先进),治疗的复杂性(医疗保健中更高的技术利用率)和人口因素(医疗而非行为健康成本随着人口年龄的增长而增加)。对卫生政策的影响:俄亥俄州的经验表明,在管理不足的情况下,ADM护理的同等水平福利是可以负担的。这表明,只要人们愿意接受有管理的护理,对阻碍ADM政策提案的成本的担忧是没有根据的。对研究的影响:成本的持续下降引发了人们对护理水平可能不足的担忧。尽管目前对成本过高的担忧是平等立法的主要政策障碍,但研究的下一步是解决护理质量或健康结果问题,这些领域的知名度甚至低于成本。©1998 John Wiley&;有限公司。
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引用次数: 66
The economic benefits of supported employment for persons with mental illness 精神病患者辅助就业的经济效益
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 1998-12-04 DOI: 10.1002/(SICI)1099-176X(199807)1:2<63::AID-MHP8>3.0.CO;2-2
Robin E. Clark, Bradley J. Dain, Haiyi Xie, Deborah R. Becker, Robert E. Drake
<p><b>Background</b>: Policies and programs that emphasize employment for persons with mental illness are often promoted with the goals of improving economic self-sufficiency and reducing dependence on public welfare programs. At present, there is little empirical evidence about the actual effect of vocational interventions on economic self-sufficiency or on use of public benefits by persons with mental illness.</p><p><b>Study Aims</b>: This study provides a preliminary look at how participating in supported employment, a form of vocational rehabilitation emphasizing ongoing support in competitive jobs, affects the amount that participants earn from work and the total amount of income they receive from all sources. Further, we examine the extent to which receiving public benefits affects the amount earned from private employment, taking into consideration other factors that might be associated with benefit status.</p><p><b>Methods</b>: Data are from a randomized trial of supported employment interventions. This analysis followed 137 of those study participants with severe mental illness for 18 months after they enrolled in either of two supported employment programs. Income from various sources was estimated based on interviews with study participants upon study entry and at six-month intervals thereafter. Changes in income from work, government and other sources were analyzed using paired Wilcoxon matched-pairs signed-ranks tests and <i>t</i>-tests. Using ordinary least-squares regression, we analyzed the effect of benefit status on changes in earnings, taking into account diagnosis, work history, education, program type, site of program, psychiatric symptoms, global functioning and previous earnings.</p><p><b>Results</b>: Estimated total income increased by an average of $134 (US) per month after enrolling in supported employment. More than three-quarters of this increase was from government sources, such as Social Security and educational grants. The increase in government income was largely due to participants applying for and getting cash benefits for the first time. Social Security payments for those receiving benefits before enrollment did not change significantly. A small group of persons (<i>n</i> = 22) who did not receive Social Security benefits before or after enrolment earned significantly more from competitive employment after enrolling than did those who received benefits. This finding persisted after taking into acount differences in work history, clinical and functional variables and education.</p><p><b>Limitations</b>: Because of the relatively small sample size and the lack of continuous measures of income these results should be considered preliminary.</p><p><b>Conclusions</b>: Supported employment, one of the more effective forms of vocational rehabilitation for persons with mental illness, did not reduce dependence on government support. Receiving government benefits was associated with lower earnings from work.</p><p><b>Imp
背景:强调精神病患者就业的政策和方案往往以提高经济自给自足和减少对公共福利方案的依赖为目标。目前,几乎没有实证证据表明职业干预措施对经济自给自足或对精神病患者使用公共福利的实际影响。研究目的:本研究初步探讨了参与支持性就业(一种强调在竞争性工作中持续支持的职业康复形式)如何影响参与者的工作收入以及他们从各种来源获得的总收入。此外,考虑到可能与福利状况相关的其他因素,我们研究了领取公共福利对私人就业收入的影响程度。方法:数据来自一项支持性就业干预的随机试验。这项分析对137名患有严重精神疾病的研究参与者进行了为期18个月的跟踪调查,这些参与者在参加了两项支持就业计划中的任何一项后。来自各种来源的收入是根据研究参与者在进入研究时的访谈以及此后每隔六个月的访谈来估计的。工作、政府和其他来源的收入变化使用配对Wilcoxon配对签名秩检验和t检验进行分析。使用普通最小二乘回归,我们分析了福利状况对收入变化的影响,考虑了诊断、工作史、教育、项目类型、项目地点、精神症状、全球功能和以前的收入。结果:在加入支持就业后,估计总收入平均每月增加134美元。其中超过四分之三的增长来自政府来源,如社会保障和教育补助。政府收入的增加主要是由于参与者首次申请并获得现金福利。那些在入学前领取福利的人的社会保障金没有显著变化。一小群在入学前或入学后没有领取社会保障福利的人(n=22)在入学后从竞争性就业中获得的收入明显高于领取福利的人。考虑到工作史、临床和功能变量以及教育程度的差异,这一发现仍然存在。局限性:由于样本量相对较小,而且缺乏持续的收入衡量标准,这些结果应被视为初步结果。结论:支持性就业是精神病患者更有效的职业康复形式之一,但并没有减少对政府支持的依赖。领取政府福利与较低的工作收入有关。对医疗保健提供和使用的影响:这些发现表明,大多数接受严重精神疾病治疗的人即使在参加职业康复计划后,也需要持续的公共财政支持。卫生政策制定的意义:毫无疑问,增加劳动力参与可以在许多方面使精神疾病患者受益。然而,政策制定者应该谨慎,在减少收入支持支出的基础上,为增加职业项目的机会辩护。此外,仅针对接受收入支持的人制定此类计划可能会忽视受益最大的客户:那些目前没有获得福利的客户。进一步研究的意义:政策制定者需要更好地了解职业干预和收入支持计划如何影响精神疾病患者的收入和福祉。类似的研究应该用更大、更多样的样本重复进行,这将允许使用工具变量统计技术。©1998 John Wiley&;有限公司。
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引用次数: 26
Economics and ethics in mental health care: traditions and trade-offs 心理健康护理中的经济学与伦理学:传统与权衡
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 1998-12-04 DOI: 10.1002/(SICI)1099-176X(199807)1:2<55::AID-MHP11>3.0.CO;2-A
Daniel Chisholm, Alan Stewart

Background: Both economic and ethical perspectives are exerting increasing influence at all levels of mental health policy and practice; yet there is little consensus on how these two different perspectives are to be reconciled or explicitly incorporated into decision-making.

Aim: This review article is directed towards a fuller understanding of the complex trade-offs and compromises that are or may be made by clinicians, managers and policy-makers alike in the context of mental health care planning and delivery.

Method: We briefly outline a number of key principles of health care economics and ethics, and then focus on the particular incentives and trade-offs that are raised by these principles at three levels of the mental health system: government and society; purchasers and providers; and users and carers.

Results: At the level of government and society, we find (economically influenced) attempts to reform mental health care offset by concerns revolving around access to care: whether society is prepared to forgo economic benefits in exchange for improved equity depends to a considerable extent on the prevailing ethical paradigm. The implementation of these reforms at the level of purchasers and providers has helped to focus attention on evaluation and prioritization, but has also introduced ‘perverse incentives’ such as cost-shifting and cream-skimming, which can impede access to or continuity of appropriate care for mentally ill people. Finally, we detect opportunities for moral hazard and other forms of strategic behaviour that are thrown up by the nature of the carer:user relationship in mental health care.

Conclusion: We conclude by highlighting the need to move towards a more open, accountable and evidence-based mental health care system. Acknowledgement of and progress towards these three requirements will not deliver ideal levels of efficiency or equity, but will foster a greater understanding of the relevance of ethical considerations to mental health policies and strategies that are often influenced strongly or solely by economic arguments, whilst also demonstrating that equity must come at a price. © 1998 John Wiley & Sons, Ltd.

背景:经济和伦理观点在心理健康政策和实践的各个层面都发挥着越来越大的影响;然而,对于如何将这两种不同的观点调和或明确纳入决策,几乎没有达成共识。目的:这篇综述文章旨在更全面地了解临床医生、管理者和决策者在心理健康护理规划和提供的背景下正在或可能做出的复杂权衡和妥协。方法:我们简要概述了医疗保健经济学和伦理学的一些关键原则,然后重点关注这些原则在心理健康系统的三个层面提出的特定激励和权衡:政府和社会;购买者和提供者;以及使用者和护理人员。结果:在政府和社会层面,我们发现(受经济影响的)改革心理健康护理的尝试被围绕获得护理的担忧所抵消:社会是否准备放弃经济利益以换取改善的公平在很大程度上取决于主流的伦理范式。在购买者和提供者层面实施这些改革有助于将注意力集中在评估和优先顺序上,但也引入了“不正当的激励措施”,如成本转移和撇奶油,这可能会阻碍精神病患者获得或连续获得适当的护理。最后,我们发现了道德风险和其他形式的战略行为的机会,这些行为是由护理者的性质引发的:心理健康护理中的用户关系。结论:最后,我们强调需要建立一个更加开放、负责和循证的精神卫生保健系统。承认这三项要求并在这方面取得进展不会带来理想的效率或公平水平,但会促进人们更好地理解道德考虑与心理健康政策和战略的相关性,这些政策和战略往往受到强烈或仅受经济论点的影响,同时也表明公平必须付出代价。©1998 John Wiley&;有限公司。
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引用次数: 10
Abstracts translations (Russian) 摘要翻译(俄语)
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 1998-12-04 DOI: 10.1002/(SICI)1099-176X(199807)1:2<101::AID-MHP13>3.0.CO;2-V
Ella Rytik Dr

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引用次数: 0
Abstracts translations 摘要翻译
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 1998-12-04 DOI: 10.1002/(SICI)1099-176X(1998100)1:3<147::AID-MHP19>3.0.CO;2-H

See PDF file for the Russian abstract translations

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引用次数: 0
Cost benefits of substance abuse treatment: an overview of results from alcohol and drug abuse 药物滥用治疗的成本效益:酒精和药物滥用结果综述
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 1998-12-04 DOI: 10.1002/(SICI)1099-176X(199803)1:1<23::AID-MHP3>3.0.CO;2-Q
Harold D. Holder Ph.D.
<p><b>Background and Methods</b>: The treatment of substance abuse is an important health service available in all industrialized countries throughout the world. Cost of treatment and its benefit or economic value is an important policy issue. Reduction in health care cost is one alternative way to measure benefits. This paper reviews a series of studies (all from the US) which address the cost–benefit question. Most studies have compared the monthly costs prior to initiation of substance abuse treatment with the costs following initiation.</p><p><b>Results from Studies of Alcoholism Treatment</b>: Many studies have found that, over the time prior to alcoholism treatment initiation, total monthly health care costs increased and costs substantially increased during the 6–12 months prior to treatment. Following treatment initiation, monthly total medical care costs declined and the overall trend was downward, i.e., the slope was negative. In contrast to the use of general health care where women typically utilize more medical care than men, overall medical care costs were found to be similar. Alcoholics of different ages, however, showed distinct medical care costs, i.e., younger patients experienced greater declines in medical care costs following alcoholism treatment initiation.</p><p>Inpatient treatment is most affected by alcoholism treatment. In some cases, outpatient treatment is actually increased in response to aftercare health care utilization, but at a substantially lower cost than inpatient treatment. If the alcoholism condition can be treated on an outpatient basis, then the total cost of such treatment is obviously lower and the potential for a cost–offset net effect is substantially increased.</p><p><b>Cost Benefits of Drug Abuse Treatment</b>: There have been few drug abuse treatment cost-benefit research studies. Early studies found that there was a decline in sickness and medical care utilization associated with initiation of treatment. A recent study found a substantial reduction in total health care costs following initiation of drug abuse treatment. Utilization of inpatient care and its associated costs are most affected by the absence and/or presence of treatment.</p><p><b>Summary and Conclusion</b>: This review describes the research findings from a number of cost-offset or cost-benefit studies of alcoholism and drug abuse treatment. In broad terms the findings of this research can be summarized as follows.</p><p>(i) Untreated alcoholics or drug dependent persons use health care and incur costs at a rate about twice that of their age and gender cohorts. (ii) Once treatment begins, total health care utilization and costs begin to drop, reaching a level that is lower than pre-treatment initiation costs after a two- to four-year period. The conclusion is based on similar findings across different patient populations using a variety of research designs. (iii) There are no apparent gender differences in the utilization and associat
背景和方法:药物滥用治疗是世界上所有工业化国家都可以提供的一项重要卫生服务。治疗成本及其效益或经济价值是一个重要的政策问题。降低医疗保健成本是衡量福利的另一种方法。本文回顾了一系列关于成本效益问题的研究(均来自美国)。大多数研究将开始药物滥用治疗前的每月费用与开始治疗后的费用进行了比较。酒精中毒治疗研究的结果:许多研究发现,在开始酒精中毒治疗之前的一段时间里,每月的总医疗费用增加,在治疗前的6-12个月内,费用大幅增加。开始治疗后,每月的总医疗费用下降,总体趋势是下降,即斜率为负。与使用一般医疗保健相比,女性通常比男性使用更多的医疗保健,总体医疗保健成本相似。然而,不同年龄的酗酒者表现出不同的医疗费用,即年轻患者在开始接受酒精中毒治疗后,医疗费用下降幅度更大。住院治疗受酗酒治疗影响最大。在某些情况下,门诊治疗实际上是为了应对善后保健的利用而增加的,但其成本远低于住院治疗。如果酒精中毒可以在门诊治疗,那么这种治疗的总成本显然更低,成本抵消净效应的可能性也大大增加。药物滥用治疗的成本效益:很少有药物滥用治疗成本效益研究。早期研究发现,与开始治疗相关的疾病和医疗保健利用率下降。最近的一项研究发现,开始药物滥用治疗后,医疗保健总成本大幅降低。住院护理的使用及其相关成本受治疗缺席和/或存在的影响最大。摘要和结论:这篇综述描述了一些酒精中毒和药物滥用治疗的成本抵消或成本效益研究的研究结果。从广义上讲,这项研究的发现可以总结如下。(i) 未经治疗的酗酒者或药物依赖者使用医疗保健,其费用约为其年龄和性别群体的两倍。(ii)一旦开始治疗,医疗保健的总利用率和费用开始下降,在两到四年后达到低于治疗前启动费用的水平。这一结论是基于不同患者群体使用各种研究设计的类似发现得出的。(iii)在开始治疗前后,利用率和相关费用没有明显的性别差异。(iv)年龄差异支持早期干预的价值。接受药物滥用治疗的年轻患者的治疗前总费用水平低于老年患者的治疗后水平。对卫生政策的影响:研究结果为药物滥用治疗的成本效益提供了一致的支持。从卫生政策的角度来看,如果目标是证明治疗投资可以通过减少其他医疗保健成本来支付其全部或部分相关成本,那么这些结果是有希望的。人们可以持相反的立场,即药物滥用者未来医疗保健费用的降低可能反映出对基本护理的拒绝。对进一步研究的影响:针对药物滥用治疗潜在成本抵消的研究主要基于所有形式的药物滥用治疗的总体或综合影响。虽然这是下一代研究应该做的,但还没有关于特定治疗模式的成本抵消的研究。©1998 John Wiley&;有限公司。
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引用次数: 67
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Journal of Mental Health Policy and Economics
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