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LETTER: Medicaid Expansion and Mental Health Care and Coverage: Reply. 信函:医疗补助扩大和精神卫生保健及覆盖范围:答复。
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2021-09-01
Samuel H Zuvekas, Chandler B McClellan, Mir M Ali, Ryan Mutter
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引用次数: 0
COMMENTARY: Medicaid Expansion and Mental Health Care and Coverage. 评论:医疗补助扩大和精神卫生保健和覆盖。
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2021-09-01
Richard G Frank
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引用次数: 0
Cost-Effectiveness of Care Environments for Improving the Mental Health of Orphaned and Separated Children and Adolescents in Kenya 改善肯尼亚孤儿和失散儿童和青少年心理健康的护理环境的成本效益
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2021-06-01
Marta Wilson-Barthes, Stavroula A Chrysanthopoulou, Lukoye Atwoli, David Ayuku, Paula Braitstein, Omar Galárraga
<p><strong>Background: </strong>Institutionalization has shown contradictory effects on the mental health of orphaned and separated children and adolescents (OSCA) in sub-Saharan Africa. There is a paucity of data surrounding the cost-effectiveness of different care environments for improving OSCA's mental health.</p><p><strong>Aims of the study: </strong>The goal of this analysis was to evaluate the cost-effectiveness of Charitable Children's Institutions (orphanages) compared to family-based settings serving OSCA in East Africa in terms of USD/unit reduction in mental health diagnoses (depression, anxiety, post-traumatic stress disorder, suicidality) and quality-adjusted life-year (QALY) gained.</p><p><strong>Methods: </strong>This economic analysis was conducted from a societal perspective as part of the Orphaned and Separated Children's Assessments Related to their (OSCAR's) Health and Well-Being Project, a 10-year longitudinal cohort study evaluating the effects of different care environments on OSCA's physical and psychological health in western Kenya. Cost data were ascertained from 9 institutions and 225 family-based settings in the OSCAR cohort via survey assessments, budget reports, and expert interviews. Monthly per-child costs were calculated as the sum of recurrent and capital costs divided by the environment's maximum residential capacity, and cost differences between care environments were estimated using two-part models. Mental health effectiveness outcomes were derived from prior survival regression analyses conducted among the OSCAR cohort. We used Child Depression Inventory Short-Form scores at baseline and follow-up to calculate the number of depression-free days (DFDs) over the follow-up period, and translated DFDs into QALYs using established utility weights. Incremental cost-effectiveness ratios (ICERs) were calculated as the difference in monthly per-child cost divided by the difference in each mental health outcome, comparing institutions to family-based settings. Sampling uncertainty in the ICERs was handled using nonparametric bootstrapping with 1,000 replications. We assumed a willingness-to-pay threshold of three times Kenya's per capita gross domestic product.</p><p><strong>Results: </strong>Charitable Children's Institutions cost USD 123 more on average than family-based settings in terms of monthly per-child expenditures (p<0.001). Compared to family-based care, institutional care resulted in an ICER of USD 236, USD 280, USD 397, and USD 456 per unit reduction in depression, anxiety, PTSD, and suicidal diagnosis among OSCA, respectively. The incremental cost per additional QALY was USD 4,929 (95% CI: USD 3096 -- USD 6740). The probability of Charitable Children's Institutions being more cost-effective than family-based settings was greater than 90% for willingness-to-pay thresholds above USD 7,000/QALY.</p><p><strong>Discussion: </strong>Only a subset of institutions in the cohort were willing to provide budgetary
背景:制度化对撒哈拉以南非洲孤儿和失散儿童和青少年(OSCA)的心理健康产生了相互矛盾的影响。关于改善OSCA心理健康的不同护理环境的成本效益的数据缺乏。本研究的目的:本分析的目的是评估慈善儿童机构(孤儿院)与以家庭为基础的机构在东非为OSCA提供服务的成本效益,以减少心理健康诊断(抑郁、焦虑、创伤后应激障碍、自杀)和获得的质量调整生命年(QALY)的美元/单位。方法:这项经济分析是从社会角度进行的,作为与他们(OSCAR)健康和福祉项目相关的孤儿和失散儿童评估的一部分,这是一项为期10年的纵向队列研究,评估了肯尼亚西部不同护理环境对OSCA身心健康的影响。通过调查评估、预算报告和专家访谈,确定了OSCAR队列中9个机构和225个家庭的成本数据。每月每个孩子的成本计算为经常性成本和资本成本之和除以环境的最大居住能力,并且使用两部分模型估计护理环境之间的成本差异。心理健康有效性结果来源于OSCAR队列中进行的既往生存回归分析。我们在基线和随访时使用儿童抑郁量表短表得分来计算随访期间无抑郁天数(dfd),并使用已建立的效用权重将dfd转换为qaly。增量成本效益比(ICERs)的计算方法是将机构与家庭环境进行比较,将每个孩子每月的成本差异除以每种心理健康结果的差异。ICERs的采样不确定性是用1000次重复的非参数自举来处理的。我们假设支付意愿的门槛是肯尼亚人均国内生产总值的三倍。结果:在每个孩子每月的支出方面,慈善儿童机构比家庭机构平均多花费123美元(p讨论:队列中只有一小部分机构愿意为这项评估提供预算信息,这可能会影响我们的成本估算。然而,没有提供预算数据的机构可能比那些收集了成本数据的机构支出更少,导致成本估算更保守。此外,我们的质量aly估计仅基于无抑郁天数,因此机构中的OSCA可能在没有额外费用的情况下获得额外的心理健康益处。对卫生政策的影响:与以家庭为基础的环境相比,机构在改善孤儿和失散儿童和青少年的心理健康结果方面可能更具成本效益。我们的研究结果表明,政策制定者应该优先考虑加强家庭护理的资源,但正式机构可以提供具有成本效益的精神卫生支持,作为最后的手段。
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引用次数: 0
Characteristics and Healthcare Burden of Patients with Schizophrenia Treated in a US Integrated Healthcare System. 美国综合医疗系统中精神分裂症患者的特点和医疗负担
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2021-06-01
Rohan Mahabaleshwarkar, Dee Lin, Kruti Joshi, Jesse Fishman, Todd Blair, Timothy Hetherington, Pooja Palmer, Charmi Patel, Constance Krull, Oleg V Tcheremissine
<p><strong>Background: </strong>Schizophrenia is one of 15 major causes of disability worldwide and is responsible for more than USD 150 billion in annual healthcare costs in the United States. Although the burden of schizophrenia as measured by healthcare resource utilization (HRU) is known to be considerable, data generally come from claims databases or healthcare systems/payors representing only a subset of patients, such as Medicare/Medicaid recipients. A broader understanding of HRU across the schizophrenia patient population would help identify underserved groups and inform strategies for improving healthcare delivery.</p><p><strong>Aims of the study: </strong>This observational study examined overall HRU and the influence of sociodemographic factors in adult patients with schizophrenia receiving care in a US integrated healthcare system.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted using data from electronic medical records (EMRs). Patients were required to have at least two diagnostic codes for schizophrenia recorded in the EMR within a 12-month period from January 2009 to June 2018, and to have received active care (≥ 1 in-system healthcare visit every six months) for at least 12 months before and after the index date (the earlier of the schizophrenia diagnosis dates). Patients were followed until no longer receiving active care or the end of the study. Patient characteristics were assessed during the 12-month pre-index period, and inpatient, readmission, emergency room (ER), and outpatient visits and antipsychotic prescriptions were described during follow-up. Findings were reported overall and in subgroups by race/ethnicity, age, and sex.</p><p><strong>Results: </strong>The study cohort included 2,941 patients (mean age, 48.3 years; 54.5% male, 51.8% black, 45.8% with Medicare). During the follow-up period (mean, 4.6 years), inpatient hospital stays were common, with at least one all-cause, mental health-related, or schizophrenia-related inpatient visit occurring for 48.7%, 47.3%, and 38.8% of patients, respectively. Hospital readmissions within 30 days of an all-cause inpatient visit occurred in 20.4% of patients, with 14.5% of patients readmitted within 30 days of a schizophrenia-related inpatient visit. More than two-thirds of patients had ER visits, and 40.7% had schizophrenia-related ER visits. Only 46.7% of patients with a schizophrenia-related inpatient visit and 58.5% of patients with a mental health-related inpatient visit had a 30-day outpatient follow-up visit. Subgroup analyses revealed that a larger proportion of non-Hispanic black vs non-Hispanic white patients had 30-day outpatient follow-up visits, ER visits, mental health specialist visits, and antipsychotic prescriptions. Moreover, older age was associated with fewer ER and mental health specialist visits and less use of injectable and second-generation antipsychotics, and women were less likely than men to receive antipsychotic therapy,
背景:精神分裂症是全球15种主要致残原因之一,在美国每年的医疗费用超过1500亿美元。虽然以医疗资源利用率(HRU)衡量的精神分裂症负担是相当大的,但数据通常来自索赔数据库或医疗保健系统/付款人,仅代表一小部分患者,如医疗保险/医疗补助接受者。更广泛地了解精神分裂症患者人群的HRU将有助于确定服务不足的群体,并为改善医疗服务提供策略提供信息。研究目的:这项观察性研究检查了在美国综合医疗保健系统中接受治疗的成年精神分裂症患者的总体HRU和社会人口因素的影响。方法:采用电子病历(EMRs)资料进行回顾性队列研究。患者被要求在2009年1月至2018年6月的12个月内至少有两个精神分裂症诊断代码记录在EMR中,并且在索引日期(精神分裂症诊断日期的较早者)之前和之后至少12个月接受积极护理(每6个月≥1次系统医疗保健访问)。随访患者直至不再接受积极治疗或研究结束。在指数前的12个月期间评估患者特征,并在随访期间描述住院、再入院、急诊室(ER)和门诊就诊情况以及抗精神病药物处方。研究结果是根据种族/民族、年龄和性别进行总体和亚组报告的。结果:研究队列纳入2941例患者(平均年龄48.3岁;54.5%男性,51.8%黑人,45.8%有医疗保险)。在随访期间(平均4.6年),住院住院很常见,至少有一次全因、精神健康相关或精神分裂症相关的住院就诊分别发生在48.7%、47.3%和38.8%的患者中。20.4%的患者在全因住院后30天内再次入院,14.5%的患者在精神分裂症相关住院后30天内再次入院。超过三分之二的患者就诊于急诊室,40.7%的患者就诊于精神分裂症相关的急诊室。只有46.7%的精神分裂症相关住院患者和58.5%的精神健康相关住院患者进行了30天的门诊随访。亚组分析显示,非西班牙裔黑人患者与非西班牙裔白人患者相比,有30天门诊随访、急诊室就诊、心理健康专家就诊和抗精神病药物处方的比例更大。此外,年龄越大,急诊室和心理健康专家就诊次数越少,注射和第二代抗精神病药物的使用也越少,女性接受抗精神病药物治疗的可能性比男性小,尤其是注射药物。讨论:在美国综合医疗保健系统中接受治疗的精神分裂症患者有相当大的急性HRU和次优的常规和随访治疗率。在人口亚组中观察到精神分裂症负担和护理的不公平。对卫生政策的影响:需要注重有效资源分配和提高卫生保健质量的人口健康管理战略,以减轻精神分裂症的负担。种族/民族、年龄和性别的差异结果表明需要优化这些亚组的护理方法。
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引用次数: 0
Farmer Suicides: Effects of Socio-Economic, Climate, and Mental Health Factors. 农民自杀:社会经济、气候和心理健康因素的影响。
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2021-06-01
Suzan Odabasi, Valentina Hartarska

Background: People working in agriculture, fishing, and forestry have elevated risks of suicide. The suicide rates for the occupations of "agriculture, fishing, and forestry" are significantly higher than any other occupation.

Aims of study: This study evaluates whether the variability in socioeconomic and demographic factors and in climate as well as the support from mental health providers and social associations affected the suicide rates of farmers in the US.

Methods: We estimate Poisson count data regression and county level-fixed effects regressions using data from the National Center for Health Statistics complemented with relevant socio-economic, climate data and data on mental health providers from a variety of sources.

Results: The results show more suicides in counties with more farms and with higher share of population without health insurance, lower agricultural wages and, in non-rural counties higher poverty rate. Surprisingly, we find more suicides in counties with more social associations, while the availability of mental health providers is associated with fewer suicides in non-rural counties, and lower suicide rate in southern counties.

Discussion: These results highlight the need for innovative targeted policy interventions instead of relying on one-size-fits-all approach. Farmers and farm workers are yet to be reached with modern and effective tools to improve mental health and prevent suicide. At the same time, factors such as the weather and climate as well as some more traditional factors such as social associations or religious participation play a limited role.

Implications for health policies: Support mechanisms have a differential effect in rural and urban areas. It is important to identify the specific demographic, climate, and policy changes that serve as external stressors and affect farm workers' suicide and accidental death from on-farm injury.

Implication for further research: Ideally, individual level data on farmers would be best in a study that evaluates what factors cause suicides.

背景:从事农业、渔业和林业工作的人自杀风险较高。“农业、渔业和林业”职业的自杀率明显高于其他任何职业。研究目的:本研究评估了社会经济和人口因素、气候以及心理健康提供者和社会协会的支持是否会影响美国农民的自杀率。方法:我们使用来自国家卫生统计中心的数据,辅以相关的社会经济、气候数据和来自各种来源的精神卫生提供者的数据,估计泊松计数数据回归和县级固定效应回归。结果:研究结果表明,在农场较多、无医疗保险人口比例较高的县,自杀率较高,农业工资较低,非农村县的贫困率较高。令人惊讶的是,我们发现更多的自杀发生在有更多社会联系的县,而在非农村县,心理健康提供者的可用性与更少的自杀有关,在南部县,自杀率更低。讨论:这些结果突出表明,需要有针对性的创新政策干预,而不是依靠一刀切的方法。农民和农场工人还没有得到现代和有效的工具来改善心理健康和预防自杀。与此同时,天气和气候等因素以及一些更传统的因素,如社会协会或宗教参与,发挥了有限的作用。对卫生政策的影响:支助机制在农村和城市地区具有不同的效果。重要的是要确定作为外部压力源并影响农场工人自杀和意外死亡的具体人口、气候和政策变化。对进一步研究的启示:理想情况下,在评估导致自杀的因素的研究中,农民的个人水平数据将是最好的。
{"title":"Farmer Suicides: Effects of Socio-Economic, Climate, and Mental Health Factors.","authors":"Suzan Odabasi,&nbsp;Valentina Hartarska","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>People working in agriculture, fishing, and forestry have elevated risks of suicide. The suicide rates for the occupations of \"agriculture, fishing, and forestry\" are significantly higher than any other occupation.</p><p><strong>Aims of study: </strong>This study evaluates whether the variability in socioeconomic and demographic factors and in climate as well as the support from mental health providers and social associations affected the suicide rates of farmers in the US.</p><p><strong>Methods: </strong>We estimate Poisson count data regression and county level-fixed effects regressions using data from the National Center for Health Statistics complemented with relevant socio-economic, climate data and data on mental health providers from a variety of sources.</p><p><strong>Results: </strong>The results show more suicides in counties with more farms and with higher share of population without health insurance, lower agricultural wages and, in non-rural counties higher poverty rate. Surprisingly, we find more suicides in counties with more social associations, while the availability of mental health providers is associated with fewer suicides in non-rural counties, and lower suicide rate in southern counties.</p><p><strong>Discussion: </strong>These results highlight the need for innovative targeted policy interventions instead of relying on one-size-fits-all approach. Farmers and farm workers are yet to be reached with modern and effective tools to improve mental health and prevent suicide. At the same time, factors such as the weather and climate as well as some more traditional factors such as social associations or religious participation play a limited role.</p><p><strong>Implications for health policies: </strong>Support mechanisms have a differential effect in rural and urban areas. It is important to identify the specific demographic, climate, and policy changes that serve as external stressors and affect farm workers' suicide and accidental death from on-farm injury.</p><p><strong>Implication for further research: </strong>Ideally, individual level data on farmers would be best in a study that evaluates what factors cause suicides.</p>","PeriodicalId":46381,"journal":{"name":"Journal of Mental Health Policy and Economics","volume":"24 2","pages":"61-71"},"PeriodicalIF":1.6,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39251781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Costs of Health Service Use among Unemployed and Underemployed People with Mental Health Problems. 有精神健康问题的失业和未充分就业人员使用卫生服务的费用。
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2021-03-01
Tamara Waldmann, Tobias Staiger, Nicolas Ruesch, Reinhold Kilian

Background: Unemployment is associated with a high risk of experiencing mental illness. This can lead to stigmatisation, reduced quality of life, and long-term costs like increased healthcare expenditure and productivity losses for society as a whole. Previous research indicates evidence for an association between unemployment and higher mental health service costs, but there is insufficient information available for the German healthcare system.

Aim of the study: This study aims to identify costs and cost drivers for health and social service use among unemployed people with mental health problems in Germany.

Methods: A sample of 270 persons participated at baseline and six-month-follow-up. Healthcare and social service use was assessed using the Client Socio-Demographic and Service Receipt Inventory. Descriptive cost analysis was performed. Associations between costs and potential cost drivers were tested using structural equation modelling.

Results: Direct mean costs for 12 months range from EUR 1265.13 (somatic costs) to EUR 2206.38 (psychiatric costs) to EUR 3020.70 (total costs) per person. Path coefficients indicate direct positive effects from the latent variable mental health burden (MHB) on stigma stress, somatic symptoms, and sick leave.

Discussion: The hypothesis that unemployed people with mental health problems seek help for somatic symptoms rather than psychiatric symptoms was not supported. Associations between MHB and costs strongly mediated by sick leave indicate a central function of healthcare provision as being confirmation of the inability to work.

Implications for health policies: Targeted interventions to ensure early help-seeking and reduce stigma remain of key importance in reducing long-term societal costs.

Implications for further research: Future research should explore attitudes regarding effective treatment for the target group.

背景:失业与经历精神疾病的高风险相关。这可能导致污名化、生活质量下降,以及整个社会的医疗支出增加和生产力损失等长期成本。先前的研究表明,失业与较高的心理健康服务成本之间存在关联,但德国医疗保健系统的可用信息不足。研究目的:本研究旨在确定德国有精神健康问题的失业人员使用健康和社会服务的成本和成本驱动因素。方法:在基线和6个月的随访中,270人参与了研究。使用客户社会人口统计和服务收据清单评估了医疗保健和社会服务的使用情况。进行描述性成本分析。成本和潜在成本驱动因素之间的关联使用结构方程模型进行了测试。结果:12个月的直接平均成本范围从每人1265.13欧元(躯体成本)到2206.38欧元(精神成本)到3020.70欧元(总成本)。路径系数表明,潜在变量心理健康负担(MHB)对病耻感压力、躯体症状和病假有直接的正向影响。讨论:有心理健康问题的失业人员寻求躯体症状而不是精神症状帮助的假设不被支持。MHB与病假介导的成本之间的关联表明,医疗保健提供的核心功能是确认无法工作。对卫生政策的影响:有针对性的干预措施,以确保早期寻求帮助和减少耻辱,在降低长期社会成本方面仍然至关重要。对进一步研究的启示:未来的研究应探讨对目标群体有效治疗的态度。
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引用次数: 0
Psychiatric Emergencies Following the 2008 Economic Recession: An Ecological Examination of Population-Level Responses in Four US States. 2008年经济衰退后的精神紧急情况:美国四个州人口水平反应的生态检查。
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2021-03-01
Parvati Singh
<p><strong>Background: </strong>Research examining mental health outcomes following economic downturns finds both pro-cyclic and counter-cyclic associations. Pro-cyclic findings (i.e. economic downturns correspond with decline in illnesses) invoke increase in leisure time and risk-averse behavior as underlying drivers of reduction in harmful consumption during economic recessions. By contrast, counter-cyclic evidence (i.e. economic downturns correspond with increase in illnesses) suggests increase in mental illness with economic decline owing to heightened stress and loss of resources, particularly among certain age and socioeconomic groups.</p><p><strong>Aim of the study: </strong>To examine the relation between monthly aggregate employment decline and psychiatric emergency department visits across 96 counties within 49 Metropolitan Statistical Areas in the United States.</p><p><strong>Methods: </strong>For this study, data on all psychiatric outpatient Emergency Department (ED) visits for 4 US states (Arizona, California, New Jersey and New York) were retrieved from the State Emergency Department Database (SEDD) and aggregated by county-month, for the time period of 2006 to 2011. Exposure to recession was operationalized as population-level employment change in a Metropolitan Statistical Area (MSA). This information was obtained from MSA-level employment provided by the US Bureau of Labor Statistics. Brief exposure time lags of 0 to 3 months were specified to estimate proximate responses to MSA-level economic decline. Income level was approximated based on insurance status (private insurance= high-income, public insurance = low-income). Linear regression analysis was used to test whether monthly decline in aggregate employment in an MSA corresponds with (i) changes in population rates of psychiatric ED visits and (ii) whether the relation between the outcome and exposure varies by insurance status (private, public) and age group (children, age < 20 years; working-age adults, age 20 to 64 years; elderly adults, age > 64 years). Regression methods controlled for region, year and month fixed effects, and state-specific linear time trends.</p><p><strong>Results: </strong>Linear regression results indicate that overall, psychiatric ED visits (per 100,000 population) decline with decline in monthly employment at exposure lag 0 (coefficient: 0.54, p < 0.001) and lag 2 (coefficient: 0.52, p < 0.001). Privately insured (high-income) groups also show a decline in psychiatric ED visits following decline in aggregate employment. Conversely, publicly insured children show an increase in psychiatric ED visit rates one month (i.e. lag 1) following employment decline (coefficient: -0.35, p value < 0.01). Exploratory analyses by disorder groups show that the population-level decline in psychiatric ED visits concentrates among visits for alcohol use disorders at 0, 1 and 2 month lags of employment decline.</p><p><strong>Discussion: </strong>This study's findings
背景:调查经济衰退后心理健康结果的研究发现了顺周期和反周期的关联。顺周期的研究结果(即经济衰退与疾病的减少相对应)将闲暇时间的增加和风险规避行为作为经济衰退期间有害消费减少的潜在驱动因素。相反,反周期证据(即经济衰退与疾病增加相对应)表明,由于压力增加和资源损失,特别是在某些年龄和社会经济群体中,精神疾病随着经济衰退而增加。研究目的:研究美国49个大都市统计区内96个县的每月总就业下降与精神科急诊就诊之间的关系。方法:本研究从州急诊科数据库(SEDD)中检索美国4个州(亚利桑那州、加利福尼亚州、新泽西州和纽约州)的所有精神科门诊急诊科(ED)就诊数据,并按县月汇总2006年至2011年期间的数据。对经济衰退的暴露被操作为大都市统计区(MSA)人口水平的就业变化。这一信息是从美国劳工统计局提供的msa级就业中获得的。0至3个月的短暂暴露时间滞后被指定用来估计对msa水平经济衰退的近似反应。收入水平是根据保险状况估算的(私人保险=高收入,公共保险=低收入)。使用线性回归分析来检验MSA中每月总就业人数的下降是否符合(i)精神科急诊科人口就诊率的变化,以及(ii)结果与暴露之间的关系是否因保险状况(私人,公共)和年龄组(儿童,年龄< 20岁;20至64岁的工作年龄成年人;老年人,年龄> 64岁)。回归方法控制了地区、年、月固定效应和特定州的线性时间趋势。结果:线性回归结果表明,总体而言,在暴露滞后0(系数:0.54,p < 0.001)和滞后2(系数:0.52,p < 0.001)时,精神科急诊科就诊人数(每10万人)随月就业人数的下降而下降。私人保险(高收入)群体的精神科急诊科就诊人数也随着总体就业人数的下降而下降。相反,公共保险儿童在就业下降后一个月(即滞后1)精神科急诊科就诊率增加(系数:-0.35,p值< 0.01)。障碍组的探索性分析表明,精神科急诊科就诊人数在人口水平上的下降集中在就业下降滞后0、1和2个月的酒精使用障碍就诊人数中。讨论:本研究的发现提供了证据,证明在MSA总就业下降后,精神科急诊就诊的正反循环趋势。尽管精神病急症的减少支持了对经济衰退的风险规避反应,但这些总体趋势可能掩盖了弱势群体之间的抵消趋势。本研究的局限性包括缺乏性别特异性分析和缺乏关于精神科急诊科急诊或非急诊性质的信息。对卫生保健提供和使用的影响:经济衰退期间精神病急诊科就诊可能因年龄和收入群体而异。对卫生政策的影响:本研究的结果可能有助于在宏观经济衰退期间为低收入群体制定有针对性的政策。对进一步研究的启示:未来的研究可能会检查经济衰退后急诊与非急诊精神科急诊科就诊的趋势。
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引用次数: 0
Drug Expenditure, Price, and Utilization in the U.S. Medicaid: A Trend Analysis for SSRI and SNRI Antidepressants from 1991 to 2018. 美国医疗补助的药物支出、价格和使用:1991年至2018年SSRI和SNRI抗抑郁药的趋势分析
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2021-03-01
Marwan Alrasheed, Ana L Hincapie, Jeff J Guo

Background: SSRIs and SNRIs are antidepressants that have largely substituted old antidepressants like Monoamine Oxidase Inhibitors (MAOIs) and Tricyclic Antidepressants (TCAs). They have been widely used since 1987 when the FDA approved the first SSRI Fluoxetine and the first SNRI Venlafaxine in 1993. Since then, several new SSRIs and SNRIs have been approved and entered the market. Utilization, pricing, and spending trends of SSRIs and SNRIs have not been analyzed yet in Medicaid.

Aim: To assess the trends of drug expenditure, utilization, and price of SSRI and SNRI antidepressants in the US Medicaid program, and to highlight the market share of SSRIs and SNRIs and the effect of generic drug entry on Medicaid drug expenditure.

Methods: A retrospective descriptive data analysis was conducted for this study. National pharmacy summary data for study brand and generic drugs were retrieved from the Medicaid State Outpatient Drug Utilization Data. These data were collected by the US Centers for Medicare and Medicaid Services (CMS). The study period was between 1991 and 2018. Study drugs include 12 different SSRI and SNRI brands and their generics available in the market, such as citalopram, escitalopram, paroxetine, fluoxetine, sertraline, venlafaxine, desvenlafaxine, duloxetine, and levomilnacipran. Data were analyzed annually and categorized by total prescriptions (utilization), total reimbursement (spending), and cost per prescription as the proxy of the price for each drug.

Results: From 1991 to 2018, total prescriptions of SSRI and SNRI drugs rose by 3001%. Total Medicaid spending on SSRIs and SNRIs increased from USD 64.5 million to USD 2 billion in 2004, then decreased steadily until it reached USD 755 million in 2018. The SSRIs average utilization market share was 87% compared to 13% of the SNRIs utilization market share. About 72% of total Medicaid spending on the two groups goes to SSRIs, while the remaining 28% goes to SNRIs. Brand SSRIs and SNRIs prices increased over time. On the contrary, generic drugs prices steadily decreased over time.

Discussion: An increase in utilization and spending for both SSRI and SNRI drugs was observed. After each generic drug entered the market, utilization shifted from the brand name to the respective generic due to their lower price. These generic substitutions demonstrate a meaningful cost-containment policy for Medicaid programs.

Implications for health policies: Our findings show the overall view of Medicaid expenditure on one of the most commonly prescribed drug classes in the US. They also provide an important insight toward the antidepressant market and the importance of monitoring different drugs and their alternatives.

背景:SSRIs和SNRIs是一种抗抑郁药,已经在很大程度上取代了旧的抗抑郁药,如单胺氧化酶抑制剂(MAOIs)和三环抗抑郁药(TCAs)。自1987年FDA批准首个SSRI类药物氟西汀和首个SNRI类药物文拉法辛以来,它们已被广泛使用。从那时起,一些新的SSRIs和SNRIs已被批准并进入市场。在医疗补助中,SSRIs和SNRIs的使用、定价和支出趋势尚未分析。目的:评估美国医疗补助计划中SSRI和SNRI抗抑郁药的药物支出、使用和价格趋势,突出SSRIs和SNRIs的市场份额以及仿制药进入对医疗补助药物支出的影响。方法:采用回顾性描述性资料分析。研究品牌药和仿制药的国家药房汇总数据从医疗补助国家门诊药物使用数据中检索。这些数据由美国医疗保险和医疗补助服务中心(CMS)收集。研究期间为1991年至2018年。研究药物包括市场上12种不同的SSRI和SNRI品牌及其仿制药,如西酞普兰、艾司西酞普兰、帕罗西汀、氟西汀、舍曲林、文拉法辛、地文拉法辛、度洛西汀和左咪那西普兰。每年对数据进行分析,并按总处方(使用率)、总报销(支出)和代表每种药物价格的每张处方成本进行分类。结果:1991 - 2018年,SSRI和SNRI类药物处方总量增长3001%。2004年,医疗补助在ssri类和snri类药物上的总支出从6450万美元增加到20亿美元,然后稳步下降,直到2018年达到7.55亿美元。SSRIs的平均使用市场份额为87%,而SNRIs的平均使用市场份额为13%。在这两组的医疗补助总支出中,约72%用于ssri类药物,其余28%用于snri类药物。品牌SSRIs和SNRIs的价格随着时间的推移而上涨。相反,随着时间的推移,仿制药的价格稳步下降。讨论:观察到SSRI和SNRI药物的使用率和支出都有所增加。每一种仿制药进入市场后,由于其价格较低,使用从品牌名称转向相应的仿制药。这些通用替代品表明,医疗补助计划的成本控制政策是有意义的。对卫生政策的影响:我们的研究结果显示了美国最常用处方药之一的医疗补助支出的总体情况。它们还为了解抗抑郁药市场以及监测不同药物及其替代品的重要性提供了重要见解。
{"title":"Drug Expenditure, Price, and Utilization in the U.S. Medicaid: A Trend Analysis for SSRI and SNRI Antidepressants from 1991 to 2018.","authors":"Marwan Alrasheed,&nbsp;Ana L Hincapie,&nbsp;Jeff J Guo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>SSRIs and SNRIs are antidepressants that have largely substituted old antidepressants like Monoamine Oxidase Inhibitors (MAOIs) and Tricyclic Antidepressants (TCAs). They have been widely used since 1987 when the FDA approved the first SSRI Fluoxetine and the first SNRI Venlafaxine in 1993. Since then, several new SSRIs and SNRIs have been approved and entered the market. Utilization, pricing, and spending trends of SSRIs and SNRIs have not been analyzed yet in Medicaid.</p><p><strong>Aim: </strong>To assess the trends of drug expenditure, utilization, and price of SSRI and SNRI antidepressants in the US Medicaid program, and to highlight the market share of SSRIs and SNRIs and the effect of generic drug entry on Medicaid drug expenditure.</p><p><strong>Methods: </strong>A retrospective descriptive data analysis was conducted for this study. National pharmacy summary data for study brand and generic drugs were retrieved from the Medicaid State Outpatient Drug Utilization Data. These data were collected by the US Centers for Medicare and Medicaid Services (CMS). The study period was between 1991 and 2018. Study drugs include 12 different SSRI and SNRI brands and their generics available in the market, such as citalopram, escitalopram, paroxetine, fluoxetine, sertraline, venlafaxine, desvenlafaxine, duloxetine, and levomilnacipran. Data were analyzed annually and categorized by total prescriptions (utilization), total reimbursement (spending), and cost per prescription as the proxy of the price for each drug.</p><p><strong>Results: </strong>From 1991 to 2018, total prescriptions of SSRI and SNRI drugs rose by 3001%. Total Medicaid spending on SSRIs and SNRIs increased from USD 64.5 million to USD 2 billion in 2004, then decreased steadily until it reached USD 755 million in 2018. The SSRIs average utilization market share was 87% compared to 13% of the SNRIs utilization market share. About 72% of total Medicaid spending on the two groups goes to SSRIs, while the remaining 28% goes to SNRIs. Brand SSRIs and SNRIs prices increased over time. On the contrary, generic drugs prices steadily decreased over time.</p><p><strong>Discussion: </strong>An increase in utilization and spending for both SSRI and SNRI drugs was observed. After each generic drug entered the market, utilization shifted from the brand name to the respective generic due to their lower price. These generic substitutions demonstrate a meaningful cost-containment policy for Medicaid programs.</p><p><strong>Implications for health policies: </strong>Our findings show the overall view of Medicaid expenditure on one of the most commonly prescribed drug classes in the US. They also provide an important insight toward the antidepressant market and the importance of monitoring different drugs and their alternatives.</p>","PeriodicalId":46381,"journal":{"name":"Journal of Mental Health Policy and Economics","volume":"24 1","pages":"3-11"},"PeriodicalIF":1.6,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25495111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medicaid Expansion and Health Insurance Coverage and Treatment Utilization among Individuals with a Mental Health Condition. 医疗补助扩大和健康保险覆盖范围以及心理健康状况个体的治疗利用。
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2020-09-01
Samuel H Zuvekas, Chandler B McClellan, Mir M Ali, Ryan Mutter
<p><strong>Background: </strong>The Affordable Care Act (ACA) gives states the option of expanding Medicaid coverage to low-income individuals; however, not all states have chosen to expand Medicaid. The ACA Medicaid expansions are particularly important for Americans with mental health conditions because they are substantially more likely than other Americans to have low incomes.</p><p><strong>Aims of the study: </strong>We examine the impact of Medicaid expansion on adults who were newly eligible for Medicaid using the 2008-2017 Medical Expenditure Panel Survey (MEPS).</p><p><strong>Methods: </strong>We use the AHRQ PUBSIM model to identify low-income adults aged 19-64 who were either newly Medicaid eligible if they lived in an expansion state or would have been eligible had their state opted to expand its Medicaid program. We estimate linear probability models within a difference-in-difference framework. An additional interaction term allows us to test for differences among those with serious psychological distress (SPD) or probable depression (PD). Outcomes of interest are insurance coverage by type, behavioral health treatment by service (specifically, any behavioral health treatment, any specialty treatment, any psychotropic medication, any ambulatory treatment outside of an emergency department, and any emergency department treatment), quantities of behavioral health treatment services, and out of pocket spending on healthcare.</p><p><strong>Results: </strong>Our adjusted difference-in-differences estimates indicate Medicaid expansion increased any insurance coverage by 14.2 percentage points and increased Medicaid coverage by 21.2 percentage points. Insurance coverage for individuals with SPD/PD in expansion states increased by an additional 12.9 percentage points. Medicaid expansion did not have an effect on behavioral health treatment for the newly eligible population as a whole or for the subset with SPD/PD.</p><p><strong>Discussion: </strong>Consistent with previous Medicaid expansions, we find that the ACA Medicaid expansions substantially increased insurance rates for the newly Medicaid-eligible population, regardless of mental health status but the overall effect on insurance coverage was stronger among those with SPD/PD. The lack of an effect on treatment use suggests that providing insurance coverage alone may be insufficient to guarantee that people with mental illness will receive the treatment they need. Limitations include that our difference-in-difference estimator may not account for time-varying factors that change contemporaneously with the expansions. Our estimates may also be affected by other provisions of the ACA that went into effect at the same time as the Medicaid expansions. IMPLICATIONS FOR HEALTH CARE PROVISION AND USE AND IMPLICATIONS FOR HEALTH POLICIES: Although the ACA has resulted in increased coverage for low-income individuals, more outreach efforts may be needed to encourage individuals with mental illne
背景:《平价医疗法案》(ACA)让各州可以选择将医疗补助扩大到低收入人群;然而,并不是所有的州都选择扩大医疗补助计划。ACA医疗补助计划的扩大对有精神健康问题的美国人尤其重要,因为他们比其他美国人更有可能是低收入人群。研究目的:我们使用2008-2017年医疗支出小组调查(MEPS)检查了医疗补助扩张对新获得医疗补助资格的成年人的影响。方法:我们使用AHRQ PUBSIM模型来确定19-64岁的低收入成年人,如果他们生活在扩大医疗补助计划的州,他们要么是新获得医疗补助资格的人,要么是如果他们的州选择扩大医疗补助计划,他们就有资格获得医疗补助。我们在差中差框架内估计线性概率模型。一个额外的相互作用项允许我们测试严重心理困扰(SPD)或可能患有抑郁症(PD)的患者之间的差异。感兴趣的结果是按类型划分的保险覆盖范围、按服务划分的行为健康治疗(具体而言,任何行为健康治疗、任何专业治疗、任何精神药物、急诊部门以外的任何门诊治疗和任何急诊部门治疗)、行为健康治疗服务的数量以及医疗保健的自付支出。结果:我们调整后的差异估计表明,医疗补助扩张使任何保险覆盖率增加了14.2个百分点,使医疗补助覆盖率增加了21.2个百分点。扩张州SPD/PD患者的保险覆盖率又增加了12.9个百分点。医疗补助计划的扩大对符合条件的新人群整体或SPD/PD子集的行为健康治疗没有影响。讨论:与之前的医疗补助扩张一致,我们发现ACA医疗补助扩张大幅提高了新获得医疗补助的人群的保险费率,无论其心理健康状况如何,但对SPD/PD患者的保险覆盖率的总体影响更强。缺乏对治疗使用的影响表明,仅提供保险范围可能不足以保证精神疾病患者得到所需的治疗。局限性包括我们的差中差估计器可能无法考虑随扩展同时变化的时变因素。我们的估计也可能受到与医疗补助扩张同时生效的ACA其他条款的影响。对卫生保健提供和使用的影响以及对卫生政策的影响:尽管ACA增加了低收入人群的覆盖范围,但可能需要更多的推广努力来鼓励精神疾病患者获得他们需要的治疗。
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引用次数: 0
Psychological Distress and Coronavirus Fears During the Initial Phase of the COVID-19 Pandemic in the United States. 美国COVID-19大流行初期的心理困扰和冠状病毒恐惧
IF 1.6 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2020-09-01
Michael T French, Karoline Mortensen, Andrew R Timming

Introduction: The COVID-19 pandemic is a significant health and economic crisis around the world. The U.S. saw a rapid escalation in laboratory-confirmed cases of COVID-19 and related deaths in March, 2020. The financial consequences of a virtual economic shutdown to curb the spread of the coronavirus are widespread and debilitating, with over 30 million Americans (about 20% of the labor force) filing for unemployment benefits since mid-March. During these unprecedented times, it is important to understand the impact of the COVID-19 pandemic on psychological distress and overall fear associated with the virus.

Data: To gain an understanding of the overall levels and predictors of psychological distress experienced in the first month of the COVID-19 pandemic in the U.S., a survey was administered online to over 2,000 individuals residing in the country. The survey instrument was administered between March 22-26, 2020, during which time the country was suffering through a period of exponential growth in COVID-19 cases and fatalities. It was administered via MTurk, a popular crowdsourcing platform increasingly used by social scientists to procure large samples over a brief period of time. A short, valid screening instrument to measure psychological distress in individuals, the Kessler 10 scale was developed in the U.S. in the 1990s as an easy-to-administer symptom assessment. The first dependent variable is the respondents' summated Kessler 10 score. The second dependent variable is a 7-category measure of how afraid the subject is about the novel coronavirus. The final dependent variable is also a 7-category scale, this time measuring self-reported likelihood of contracting the coronavirus. A variety of socio-demographic variables and health status were collected to analyze factors associated with psychological distress and mental health.

Methods: Ordinary Least Squares (OLS) multiple regression was employed to analyze these data.

Results: We find that protective factors against psychological distress include age, gender (male), and physical health. Factors exacerbating psychological distress include Hispanic ethnicity and a previous mental illness diagnosis. Similar factors are significantly related to fear of the virus and self-assessed likelihood of contracting it.

Discussion: The COVID-19 pandemic is associated with high levels of psychological distress in the U.S. The Kessler 10 mean value in our sample is 21.12, which falls in the likely to experience mild mental illness category, yet is considerably higher compared to one of the largest and earliest benchmark studies validating the scale. Psychological distress is one element of overall mental health status that could be influenced by the COVID-10 pandemic. Other mental health conditions such as depression, anxiety, and substance use disorders could also be affected by the pandemic

2019冠状病毒病大流行是一场全球性的重大卫生和经济危机。2020年3月,美国实验室确诊的COVID-19病例和相关死亡人数迅速上升。为遏制冠状病毒的传播而实施的实际经济关闭的财务后果是广泛而令人虚弱的,自3月中旬以来,已有3000多万美国人(约占劳动力的20%)申请失业救济。在这前所未有的时期,重要的是要了解COVID-19大流行对与病毒相关的心理困扰和整体恐惧的影响。数据:为了了解美国COVID-19大流行第一个月所经历的心理困扰的总体水平和预测因素,对居住在该国的2000多名个人进行了在线调查。该调查工具于2020年3月22日至26日进行,在此期间,该国正经历COVID-19病例和死亡人数呈指数级增长的时期。它是通过MTurk管理的,MTurk是一个流行的众包平台,社会科学家越来越多地使用它来在短时间内获取大量样本。凯斯勒10量表是一种测量个体心理困扰的简短有效的筛查工具,于20世纪90年代在美国开发,作为一种易于管理的症状评估。第一个因变量是被调查者的凯斯勒总分。第二个因变量是一个7类指标,衡量受试者对新型冠状病毒的恐惧程度。最后一个因变量也是一个7类量表,这一次测量的是自我报告感染冠状病毒的可能性。收集各种社会人口变量和健康状况,分析与心理困扰和心理健康相关的因素。方法:采用普通最小二乘(OLS)多元回归对数据进行分析。结果:年龄、性别(男性)和身体健康状况是预防心理困扰的保护因素。加剧心理困扰的因素包括西班牙裔和先前的精神疾病诊断。类似的因素也与对病毒的恐惧和自我评估感染病毒的可能性密切相关。讨论:在美国,COVID-19大流行与高水平的心理困扰有关。我们样本中的凯斯勒10均值为21.12,属于可能经历轻度精神疾病的类别,但与验证该量表的最大和最早的基准研究之一相比,这一数值要高得多。心理困扰是可能受到COVID-10大流行影响的整体心理健康状况的一个因素。其他精神健康状况,如抑郁、焦虑和物质使用障碍也可能受到大流行的影响。我们鼓励研究人员在未来关于COVID-19大流行的研究中检查这些和其他精神健康障碍。结论:在疫情早期,心理困扰的平均得分相对较高(21.12分),这表明政府官员、政策制定者和公共卫生倡导者应迅速采取行动,解决新出现的心理健康问题。
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引用次数: 0
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Journal of Mental Health Policy and Economics
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