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Updated ASM Curriculum Guidelines describe core microbiology content to modernize the framework for microbiology education. 更新的 ASM 课程指南描述了核心微生物学内容,使微生物学教育框架现代化。
IF 1.6 Q2 EDUCATION, SCIENTIFIC DISCIPLINES Pub Date : 2024-10-21 DOI: 10.1128/jmbe.00126-24
Nancy Boury, Amy Siegesmund, David B Kushner, Davida S Smyth, Mary E Allen, Adronisha Frazier, Illona Gillette-Ferguson, Miriam Markum, Glenn Patriquin, Sara E Reynolds, Sarah Rosario, J Jordan Steel, Rachel Horak

Curricular guidelines promote standardized approaches to coverage of essential knowledge and skills in undergraduate education. The American Society for Microbiology (ASM) Curriculum Guidelines for Undergraduate Microbiology were developed in 2012. Continuous, rapid growth of knowledge in science and a dynamic, changing world necessitate updates to these guidelines. As such, ASM formed a task force in the summer of 2022. The task force assessed the 2012 ASM Curriculum Guidelines considering advancements in technology, an understanding of an expanded role of microbes, and a broader scope addressing relevant social and environmental aspects of microbiology. Language in the updated guidelines was also modified to better include eukaryotic microbes, viruses, and other acellular microbes. The task force formed working groups, each aimed at revising specific sections of the 2012 ASM Curriculum Guidelines. The revisions to the ASM Curriculum Guidelines were reviewed by subject matter experts and education stakeholders. Feedback from this peer review was incorporated into the updated guidelines, and further comments were solicited from the ASM Conference of Undergraduate Educators (ASMCUE) attendees in November 2023 before these guidelines were finalized. In this article, we describe the rationale and development of updated ASM Curriculum Guidelines which identify foundational concepts that will serve to improve microbial literacy and that can be expanded upon to address more advanced and specialized topics.

课程指南提倡在本科教育中采用标准化的方法来涵盖基本知识和技能。美国微生物学会(ASM)本科微生物学课程指南于 2012 年制定。科学知识的持续快速增长以及世界的动态变化要求对这些指南进行更新。因此,ASM 在 2022 年夏天成立了一个特别工作组。考虑到技术的进步、对微生物作用扩大的理解以及涉及微生物学相关社会和环境方面的更广泛范围,特别工作组对 2012 年 ASM 课程指南进行了评估。更新版指南中的语言也进行了修改,以便更好地纳入真核微生物、病毒和其他无细胞微生物。特别工作组成立了多个工作组,每个工作组的目标都是修订《2012 年美国微生物学会课程指南》的具体章节。学科专家和教育利益相关者对《ASM 课程指南》的修订进行了审查。同行评审的反馈意见被纳入更新后的指南,在指南最终定稿之前,我们还向 2023 年 11 月举行的 ASM 本科生教育者大会 (ASMCUE) 的与会者征集了进一步的意见。在本文中,我们介绍了更新版 ASM 课程指南的基本原理和制定过程,该指南确定了有助于提高微生物素养的基础概念,并可在此基础上扩展以解决更高级和更专业的主题。
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引用次数: 0
Addressing the need to facilitate undergraduate research experiences for community college transfer students in science. 满足社区学院理科转学生对促进本科生研究经历的需求。
IF 1.6 Q2 EDUCATION, SCIENTIFIC DISCIPLINES Pub Date : 2024-10-21 DOI: 10.1128/jmbe.00090-24
Emma C Goodwin, Katelyn M Cooper, Logan E Gin, Sara E Brownell

Community college transfer students face numerous challenges, including gaining access to undergraduate research experiences. In this Perspectives piece, we articulate the benefits of undergraduate research experiences for community college transfer students, some of the common barriers for engaging transfer students in undergraduate research, and how 4-year institutions can address these problems through the development of transfer-specific programs. We specifically discuss the LEAP Scholars program, which we designed for low-income community college transfer students. The LEAP Scholars program helped students learn about undergraduate research through their participation in a science education course-based undergraduate research experience and facilitated student access to undergraduate research experiences in science faculty member research labs.

社区大学的转学生面临着众多挑战,其中包括获得本科研究经历的机会。在这篇《视角》文章中,我们阐述了本科研究经历对社区大学转校生的益处、转校生参与本科研究的一些常见障碍,以及四年制院校如何通过开发针对转校生的项目来解决这些问题。我们特别讨论了为低收入社区大学转学生设计的 LEAP 学者计划。LEAP 学者计划帮助学生通过参加以科学教育课程为基础的本科生研究体验来了解本科生研究,并促进学生在理科教师的研究实验室中获得本科生研究体验。
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引用次数: 0
Validating an instrument for measuring community cultural wealth with biology majors at a Hispanic-serving institution. 在一所为西班牙裔服务的院校中,与生物专业的学生一起验证用于衡量社区文化财富的工具。
IF 1.6 Q2 EDUCATION, SCIENTIFIC DISCIPLINES Pub Date : 2024-10-03 DOI: 10.1128/jmbe.00123-24
Alexander Eden, Bryan M Dewsbury

Boosting underrepresented student persistence in STEM majors has been of interest for several years. Prior research has explored various factors that may influence student success and persistence in STEM majors. Specifically, some of these studies have employed Yosso's community cultural wealth framework to explore how a student's cultural wealth may link to certain outcomes. Most of these studies have taken a qualitative approach when exploring cultural wealth and less adopt a quantitative approach. Using biology students in an introductory biology class during the fall (n = 303) and spring semesters (n = 215) at a large Hispanic-serving institution in the southeastern United States, this study seeks to contribute to the literature by validating a previously constructed instrument with a new population. An exploratory factor analysis (EFA) was conducted using principal axis factoring and an oblique rotation. EFA results revealed 10 dimensions of cultural wealth. Additionally, confirmatory factor analysis confirmed that the model produced properly measures the constructs as intended. Overall, the final 56-item instrument used in this study was validated and can be used for measuring cultural wealth in similar populations.

多年来,提高科技、工程和数学(STEM)专业中代表性不足的学生的持续学习能力一直备受关注。先前的研究探讨了可能影响学生在 STEM 专业中取得成功和坚持学习的各种因素。具体而言,其中一些研究采用了 Yosso 的社区文化财富框架来探讨学生的文化财富如何与某些结果相关联。这些研究在探讨文化财富时大多采用定性方法,较少采用定量方法。本研究以美国东南部一所为西班牙裔服务的大型院校秋季学期(n = 303)和春季学期(n = 215)生物入门班的学生为研究对象,试图通过在新的人群中验证以前构建的工具来为文献做出贡献。研究采用主轴因子法和斜向旋转法进行了探索性因子分析(EFA)。EFA 结果显示了文化财富的 10 个维度。此外,确认性因子分析也证实了所建立的模型能够恰当地测量预期的结构。总之,本研究中使用的 56 个项目的最终工具得到了验证,可用于测量类似人群的文化财富。
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引用次数: 0
Knowledge and perception of antibiotic resistance and stewardship among pre-health and agriculture undergraduate students. 卫生和农业专业本科生对抗生素耐药性和管理的认识和看法。
IF 1.9 Q2 EDUCATION, SCIENTIFIC DISCIPLINES Pub Date : 2024-09-18 DOI: 10.1128/jmbe.00069-24
Claudia Da Silva Carvalho
The global threat of antibiotic-resistant infections has resulted in health organizations compiling an Antibiotic Stewardship Program (ASP), in which the education of current and future medical prescribers and farmers is central to the preservation of current and future antimicrobial treatments. The purpose of this study was to assess and compare the knowledge and perceived threat of antibiotics and antibiotic resistance, as well as the perceived benefit of antibiotic stewardship education, among undergraduate students majoring in Biology and Agriculture at Fort Hays State University. I hypothesized that the difference in knowledge and perceptions between Biology and Agriculture students would be significantly different because of differences in curriculum requirements. Framed by the health belief model (HBM), a quantitative cross-sectional study was conducted using a structured online survey of 136 undergraduate student participants. A χ2 analysis was used to assess differences between the respondents in their knowledge and perceptions of antibiotics, antibiotic resistance, and antibiotic stewardship education at the undergraduate level. Results showed that, although Agriculture students perceived antibiotic resistance as less threatening than Biology/pre-health students, both undergraduate groups were knowledgeable about the problem and wanted more academic education on the issue. These findings create a solid foundation to initiate a conversation on the curriculum development to meet ASP goals and objectives at the undergraduate level while contributing to an ongoing international effort to educate future prescribers and farmers on the importance of antibiotics in medicine and farming and to reduce antibiotic resistance.
抗生素耐药性感染对全球造成的威胁促使卫生机构制定了抗生素管理计划(ASP),其中对当前和未来的医疗处方者和农民进行教育是保护当前和未来抗菌治疗的核心。本研究的目的是评估和比较海斯堡州立大学生物和农业专业的本科生对抗生素和抗生素耐药性的认识和感知威胁,以及对抗生素管理教育的感知益处。我假设,由于课程要求不同,生物专业学生和农学专业学生在知识和认知方面的差异会很大。在健康信念模型(HBM)的框架下,我们对 136 名本科生参与者进行了结构化在线调查,从而开展了一项定量横断面研究。研究采用χ2分析法评估了受访者对抗生素、抗生素耐药性和抗生素管理教育的认识和看法在本科阶段的差异。结果表明,虽然农学院学生认为抗生素耐药性的威胁性低于生物/健康预科学生,但两个本科生群体都对这一问题有所了解,并希望在这一问题上得到更多的学术教育。这些发现为启动课程开发对话奠定了坚实的基础,以实现 ASP 在本科阶段的目标和目的,同时为正在进行的国际努力做出贡献,教育未来的处方医生和农民了解抗生素在医学和农业中的重要性,并减少抗生素耐药性。
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引用次数: 0
Graduate teaching assistants' beliefs and practices regarding mentoring in the context of an online introductory biology CURE: an exploratory study. 研究生助教在在线生物入门 CURE 中的指导信念和实践:一项探索性研究。
IF 1.9 Q2 EDUCATION, SCIENTIFIC DISCIPLINES Pub Date : 2024-09-13 DOI: 10.1128/jmbe.00150-24
Karen A Santillan,Andrea M Rediske,Jeffrey T Olimpo
Course-based undergraduate research experiences (CUREs) have been identified as a promising approach to engage large numbers of students in discovery-based investigations in the biological sciences. As the prevalence of CUREs continues to increase nationwide, the role of graduate teaching assistants (TAs) in facilitating these courses has simultaneously grown. In addition to serving as instructors of CUREs, previous research suggests that educators-including TAs-must also adopt additional roles, including that of a mentor. However, few studies have explicitly examined CURE TAs' beliefs and practices regarding mentorship. To address this need, we conducted an exploratory, concurrent mixed methods study to better understand TAs' self-reported mentoring skills levels and their experiences acting as potential mentors in the context of an online introductory biology SEA-PHAGES CURE. Results indicate that TAs (N = 12) believed themselves most skilled in areas related to listening and communication, building rapport with students, and encouraging independence with respect to student research projects. Analysis of open-ended survey data further demonstrated that the overwhelming majority of TAs (n = 10) considered themselves to be mentors, citing a diversity of rationales reflective of both psychosocial and instrumental forms of mentoring support. Collectively, these outcomes contribute to a growing body of literature on the nature and level of involvement of TAs within CURE learning environments, particularly with respect to their posited role as mentors.
以课程为基础的本科生研究经历(CUREs)被认为是让大量学生参与生物科学领域以发现为基础的研究的一种很有前途的方法。随着 CUREs 在全国范围内的普及,研究生助教(TAs)在促进这些课程中的作用也在同步增长。以往的研究表明,教育者(包括助教)除了担任 CUREs 的指导教师外,还必须扮演其他角色,包括导师的角色。然而,很少有研究明确考察了团结与种族平等教育助教在导师制方面的信念和实践。为了满足这一需求,我们开展了一项探索性、并行混合方法研究,以更好地了解助教自我报告的指导技能水平,以及他们在在线生物入门 SEA-PHAGES CURE 中担任潜在指导者的经历。结果表明,助教(N = 12)认为自己在倾听与交流、与学生建立融洽关系以及鼓励学生独立完成研究项目等方面的技能最为娴熟。对开放式调查数据的分析进一步表明,绝大多数助教(n = 10)认为自己是导师,并列举了各种理由,反映了指导支持的社会心理和工具形式。总之,这些成果为越来越多关于助教在团结与种族平等委员会学习环境中的参与性质和程度的文献做出了贡献,尤其是关于助教作为导师的假设角色。
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引用次数: 0
PULSE Ambassadors program: empowering departments to transform STEM education for inclusion and student success. PULSE 大使计划:增强各部门改造 STEM 教育的能力,以实现包容和学生的成功。
IF 1.9 Q2 EDUCATION, SCIENTIFIC DISCIPLINES Pub Date : 2024-09-12 DOI: 10.1128/jmbe.00052-24
Alix D Dowling Fink,Taylor Allen,Paul E Arriola,Edwin J Barea-Rodriguez,Nitya P Jacob,Michael Ira Kelrick,Joann Otto,C Gary Reiness,Jacqueline Washington
The Partnership for Undergraduate Life Sciences Education (PULSE) is a non-profit educational organization committed to promoting the transformation of undergraduate STEM education by supporting departments in removing barriers to access, equity, and inclusion and in adopting evidence-based teaching and learning practices. The PULSE Ambassadors Campus Workshop program enables faculty and staff members of host departments to 1) develop communication, shared leadership, and inclusion skills for effective team learning; 2) implement facilitative leadership skills (e.g., empathic listening and collaboration); 3) create a shared vision and departmental action plan; and 4) integrate diversity, equity, and inclusion practices in the department and curriculum. From the first workshop in 2014, teams of trained Ambassadors conducted workshops at 58 institutions, including associate, bachelor, master, and doctoral institutions. In their workshop requests, departments cited several motivations: desire to revise and align their curriculum with Vision and Change recommendations, need for assistance with ongoing curricular reform, and wish for external assistance with planning processes and communication. Formative assessments during and immediately following workshops indicated that key outcomes were met. Post-workshop interviews of four departments confirm progress achieved on action items and development of individual department members as agents of change. The PULSE Ambassadors program continues to engage departments to improve undergraduate STEM education and prepare departments for the challenges and uncertainties of the changing higher education landscape.
本科生生命科学教育合作组织(PULSE)是一个非营利性教育组织,致力于通过支持各院系消除入学、公平和包容方面的障碍以及采用循证教学实践来促进本科生 STEM 教育的转型。PULSE 大使校园工作坊计划使主办部门的教职员工能够:1)发展有效团队学习的沟通、共同领导和包容技能;2)实施促进性领导技能(如移情聆听和协作);3)创建共同愿景和部门行动计划;以及 4)在部门和课程中整合多样性、公平性和包容性实践。从 2014 年的第一次研讨会开始,经过培训的大使团队在 58 所院校举办了研讨会,包括副学士、学士、硕士和博士院校。在提出举办研讨会的请求时,各院系提出了几个动机:希望根据 "愿景与变革 "的建议修订和调整课程;在持续的课程改革中需要帮助;希望在规划流程和沟通方面获得外部援助。研讨会期间和紧接研讨会之后进行的形成性评估表明,主要成果均已实现。对四个系进行的工作坊后访谈证实了在行动项目上取得的进展,以及各系成员作为变革推动者的发展。PULSE 大使计划将继续与各院系合作,以改善本科生的 STEM 教育,并使各院系做好准备,应对不断变化的高等教育环境中的挑战和不确定性。
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引用次数: 0
Collaborative learning in the digital age: empowering tuberculosis researchers through virtual training. 数字时代的协作学习:通过虚拟培训增强结核病研究人员的能力。
IF 1.9 Q2 EDUCATION, SCIENTIFIC DISCIPLINES Pub Date : 2024-09-11 DOI: 10.1128/jmbe.00114-24
Anzaan Dippenaar,Taime Sylvester,Christopher Ealand,Nabila Ismail,Niaina Rakotosamimanana,Michele Miller,Bavesh D Kana,Rob M Warren,
Integrating whole genome sequencing (WGS) of the Mycobacterium tuberculosis complex into routine care, surveillance, and research in high tuberculosis burden settings remains challenging due to limited resources and skills. While technological platforms for scaling WGS are emerging, scaling wet lab and analytic components often depends on partnerships where such skills have been established. To address this, a virtual training program was developed. Over 12 weeks, 21 trainees from five Southern African institutes engaged in learning from curated theoretical content and interactive virtual meetings with experienced instructors. The training program, developed by a diverse team of experts in molecular biology, biomedical research, microbiology, and tuberculosis research, provided comprehensive coverage aligned with the latest advancements. Teaching strategies included interactive mentor-led sessions and real-time feedback, together with facilitated knowledge exchange and understanding. The virtual training program yielded several successes. Of note, trainees submitted three scientific articles for peer review, based on their acquired knowledge and its application in research. The program also fostered collaborations on Mycobacterium tuberculosis WGS among participants, showcasing the potential for networking and future joint projects. While the virtual training program encountered challenges related to the pandemic, limited resources, trainee engagement, and language barriers, these were creatively mitigated. To improve future training sessions, a platform assessing participant engagement and information retention is recommended. Wider collaborative efforts among experts and institutions in collating resources will lead to more comprehensive training programs. Addressing challenges such as internet connectivity issues and language barriers is crucial for ensuring inclusivity and enhancing the overall learning experience. In conclusion, the virtual training program successfully provided knowledge and skill training in WGS to trainees, leading to scientific article submissions and collaborations. Furthermore, content creators benefited from improved science communication and training opportunities.
由于资源和技能有限,将结核分枝杆菌复合体的全基因组测序(WGS)纳入结核病高负担地区的日常护理、监测和研究工作仍具有挑战性。虽然扩大 WGS 规模的技术平台正在出现,但扩大湿实验室和分析组件的规模往往取决于已建立此类技能的合作伙伴关系。为此,我们开发了一个虚拟培训计划。在为期 12 周的时间里,来自南部非洲 5 个研究所的 21 名受训人员参与学习了精心策划的理论内容,并与经验丰富的讲师进行了互动式虚拟会议。该培训计划由分子生物学、生物医学研究、微生物学和结核病研究领域的不同专家团队开发,提供了与最新进展相一致的全面内容。教学策略包括导师主导的互动课程和实时反馈,以及促进知识交流和理解。虚拟培训计划取得了多项成果。值得一提的是,学员们根据所学知识及其在研究中的应用,提交了三篇科学文章供同行评审。该计划还促进了学员之间在结核分枝杆菌 WGS 方面的合作,展示了联网和未来联合项目的潜力。虽然虚拟培训计划遇到了与大流行病、有限资源、学员参与和语言障碍有关的挑战,但这些挑战都得到了创造性的缓解。为了改进今后的培训课程,建议建立一个平台,评估学员的参与情况和信息保留情况。专家和机构之间在整理资源方面更广泛的合作将促成更全面的培训计划。应对互联网连接问题和语言障碍等挑战对于确保包容性和提升整体学习体验至关重要。总之,虚拟培训计划成功地为学员提供了 WGS 方面的知识和技能培训,促成了科学文章的提交和合作。此外,内容创作者也从更好的科学交流和培训机会中受益。
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引用次数: 0
PROPEL: a scalable model for postbaccalaureate training to promote diversity in the biomedical workforce. PROPEL:可扩展的学士后培训模式,以促进生物医学劳动力的多样性。
IF 1.6 Q2 EDUCATION, SCIENTIFIC DISCIPLINES Pub Date : 2024-09-10 DOI: 10.1128/jmbe.00122-24
Jessica Allen, Ekland Abdiwahab, Meghan D Morris, Claude Jourdan Le Saux, Paola Betancur, K Mark Ansel, Ryan D Hernandez, Todd G Nystul

Promoting diversity in the scientific workforce is crucial for harnessing the potential of available talent and ensuring equitable access to Science, Technology, Engineering, Mathematics, and Medicine (STEM-M) careers. We have developed an innovative program called Postbaccalaureate Research Opportunity to Promote Equity in Learning (PROPEL) that provides scientific and career development training for postbaccalaureate scholars from historically excluded backgrounds in STEM-M fields with an interest in pursuing a PhD or MD/PhD degree. Our program is distinct from other postbaccalaureate programs in that scholars are hired by individual labs rather than funded centrally by the program. This funding mechanism removes the idea that central funding is necessary to encourage faculty to train diverse scholars and allows the program to scale dynamically according to the needs of the scientific community. The PROPEL program started in 2020 with six scholars and has since grown to an enrollment of over 100, making it the largest postbaccalaureate program for biomedical research in the country. Here, we describe the program structure and curriculum, our strategy for recruitment, the enrollment trends, the program demographics, metrics of scholar engagement, and outcomes for scholars who completed the program in 2023. Our experience demonstrates the strong demand from both scholars and faculty for programming of this type and describes the feasibility of implementation.

促进科学人才队伍的多元化对于发挥现有人才的潜力以及确保公平地获得科学、技术、工程、数学和医学(STEM-M)职业至关重要。我们制定了一项名为 "促进学习公平的学士后研究机会"(PROPEL)的创新计划,为来自 STEM-M 领域、历来受排斥、有志于攻读博士学位或医学博士/博士学位的学士后学者提供科学和职业发展培训。我们的项目与其他学士后项目的不同之处在于,学者由各个实验室聘用,而不是由项目集中资助。这种资助机制消除了中央资助是鼓励教师培养多元化学者的必要条件这一想法,并使该计划能够根据科学界的需求动态扩展。PROPEL 项目于 2020 年启动,最初只有六名学者,后来发展到 100 多人,成为美国最大的生物医学研究学士后项目。在此,我们将介绍项目的结构和课程、招生策略、招生趋势、项目人口统计、学者参与度指标以及 2023 年完成项目的学者的成果。我们的经验证明了学者和教师对此类项目的强烈需求,并介绍了项目实施的可行性。
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引用次数: 0
Opportunities for guiding development: insights from first-year life science majors' use of metacognition. 指导发展的机会:从一年级生命科学专业学生使用元认知中获得的启示。
IF 1.6 Q2 EDUCATION, SCIENTIFIC DISCIPLINES Pub Date : 2024-09-05 DOI: 10.1128/jmbe.00053-24
Julie Dangremond Stanton, Stephanie M Halmo, Rayna J Carter, Kira A Yamini, Deborah Ososanya

Students with strong metacognitive skills are positioned to learn and achieve more than peers who are still developing their metacognition. Yet, many students come to college without well-developed metacognitive skills. As part of a longitudinal study on metacognitive development, we asked when, why, and how first-year life science majors use metacognitive skills of planning, monitoring, and evaluating. Guided by the metacognition framework, we collected data from 52 undergraduates at three institutions using semi-structured interviews. We found that first-year students seek study recommendations from instructors, peers, and online resources when they plan their study strategies. First-year students struggle to accurately monitor their understanding and benefit when instructors help them confront what they do not yet know. First-year students evaluate the effectiveness of their study plans at two specific points: immediately after taking an exam and/or after receiving their grade on an exam. While first-year students may be particularly open to suggestions on how to learn, they may need help debunking myths about learning. First-year students acknowledge they are still learning to monitor and welcome formative assessments that help them improve the accuracy of their monitoring. First-year students may be primed to receive guidance on their metacognition at the points when they are most likely to evaluate the effectiveness of their study strategies and plans. Based on our results, we offer suggestions for instructors who want to support first-year students to further develop their metacognition.

元认知能力强的学生比元认知能力尚待提高的学生学习能力更强,成绩更好。然而,许多学生在进入大学时,元认知能力并没有得到很好的发展。作为元认知发展纵向研究的一部分,我们询问了生命科学专业一年级学生何时、为何以及如何使用计划、监控和评估等元认知技能。在元认知框架的指导下,我们通过半结构式访谈收集了三所院校 52 名本科生的数据。我们发现,一年级学生在规划学习策略时,会从导师、同学和网络资源中寻求学习建议。一年级学生很难准确监控自己对知识的理解,而当教师帮助他们正视自己尚未掌握的知识时,他们会受益匪浅。一年级学生在两个特定的时间点评估学习计划的有效性:考试后和/或考试成绩出来后。一年级学生可能特别乐于接受关于如何学习的建议,但他们可能需要帮助来揭穿关于学习的迷思。一年级学生承认他们仍在学习监控,并欢迎能帮助他们提高监控准确性的形成性评估。一年级学生在最有可能评估自己的学习策略和计划的有效性的时候,可能最容易接受有关元认知的指导。基于我们的研究结果,我们为希望支持一年级学生进一步发展元认知的教师提供了建议。
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引用次数: 0
Optogenetic control of Drosophila neurons: a laboratory practical for undergraduates and outreach. 果蝇神经元的光遗传学控制:面向本科生和推广人员的实验室实践。
IF 1.6 Q2 EDUCATION, SCIENTIFIC DISCIPLINES Pub Date : 2024-09-03 DOI: 10.1128/jmbe.00086-24
Andrew D Renault

Teaching aspects of neuroscience to large undergraduate classes can be difficult in terms of the cost of equipment involved such as microscopes and electrophysiology equipment, the time taken to master techniques such as dissection or intracellular recording, and ethical concerns when using vertebrates. Here, I describe a practical that uses behavioral readouts and optogenetics on Drosophila that can be implemented with minimal cost as well as reduced ethical concerns and uses mostly observational techniques. The practical can be used to teach aspects of genetics and the tools for manipulating neuronal activity for ascribing neuronal function. The practical can be customized to fit different undergraduate levels and learning objectives.

在大班本科生中讲授神经科学方面的知识可能很困难,因为涉及到显微镜和电生理设备等设备的成本、掌握解剖或细胞内记录等技术所需的时间,以及使用脊椎动物时的伦理问题。在这里,我将介绍一种在果蝇身上使用行为读数和光遗传学的实践方法,这种方法可以以最低的成本实施,并减少了伦理方面的顾虑,而且主要使用的是观察技术。该实践可用于教授遗传学方面的知识以及操纵神经元活动以确定神经元功能的工具。该实践活动可根据不同的本科生水平和学习目标进行定制。
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引用次数: 0
期刊
Journal of Microbiology & Biology Education
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