Revista Espanola de Anestesiologia y Reanimacion最新文献

英文中文

Reglas de predicción clínica en los pacientes con dolor neuropático periférico de etiología traumática tratados con parche de capsaicina al 8% 用辣椒素贴片治疗的外源性周围神经性疼痛患者的临床预测规则

IF 0.8 Q3 ANESTHESIOLOGY

Revista Espanola de Anestesiologia y Reanimacion

Pub Date : 2025-06-26 DOI: 10.1016/j.redar.2025.501880

L. Monteagudo Moreno , P. Cía Blasco , M. Malo Urriés , A. Nuez Polo , C. Marín Zaldívar

Background and objectives

Neuropathic pain (NP) is a widespread, complex disorder that responds differently to pharmacological treatment. The aim of this study was to identify the baseline characteristics of good response to capsaicin 8% patch in patients with trauma-induced peripheral neuropathic pain (PNP).

Materials and methods

We performed a prospective, longitudinal, open-label study in 31 patients with PNP treated with 1-3 applications of the capsaicin 8% patch for 52 weeks. Response to treatment was defined as a reduction in the Visual Analogue Scale (VAS) score compared to baseline. Data from responders and non-responders were compared at the start (month 1) and end (month 12) of treatment. Logistic regression was used to identify predictors of treatment response.

Results

At month 1, responders (n = 17) had significantly larger treatment areas (155.18 cm² vs. 59.21 cm²; P=.004) and reported greater pain relief with treatments received in the previous week in the brief pain questionnaire (34.7% vs. 14.3%; P=.023). At month 12, significant predictors included cold allodynia (OR 8; P=.030), positive for painful cold in the DN4 questionnaire (OR 7.936; P=.019), no penetrating pain (OR 16.800; P=.009), and pain interference with work score < 7.5 (OR 7.917; P=.019).

Conclusions

This study makes a significant contribution to the management of post-traumatic peripheral neuropathic pain by providing tools to personalize treatment and optimize available resources.

背景和目的神经性疼痛（NP）是一种广泛而复杂的疾病，对药物治疗的反应不同。本研究的目的是确定8%辣椒素贴片对创伤性周围神经性疼痛（PNP）患者良好反应的基线特征。材料和方法我们对31例PNP患者进行了一项前瞻性、纵向、开放标签的研究，这些患者接受1-3次8%辣椒素贴剂治疗，持续52周。对治疗的反应被定义为视觉模拟量表（VAS）评分较基线的降低。在治疗开始（第1个月）和结束（第12个月）比较应答者和无应答者的数据。采用Logistic回归来确定治疗反应的预测因素。结果在第1个月，有应答者（n = 17）的治疗面积显著增大(155.18 cm2 vs. 59.21 cm2；P= 0.004)，并且在简短疼痛问卷中报告前一周接受治疗的患者疼痛缓解更大(34.7% vs. 14.3%；P = 0)。在第12个月，显著的预测因子包括冷性异常性痛(OR 8；P= 0.030)， DN4问卷中疼痛性感冒阳性(OR 7.936；P= 0.019)，无穿透性疼痛(OR 16.800；P= 0.009)，疼痛干扰工作得分<；7.5(或7.917；P = .019)。结论本研究为创伤后周围神经性疼痛的治疗提供了个性化治疗和优化现有资源的工具，对创伤后周围神经性疼痛的治疗有重要贡献。

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引用次数: 0

Manejo perioperatorio de los pacientes en tratamiento con agonistas del receptor GLP-1: riesgos y recomendaciones GLP-1受体激动剂治疗患者术后管理：风险和建议

IF 0.8 Q3 ANESTHESIOLOGY

Revista Espanola de Anestesiologia y Reanimacion

Pub Date : 2025-06-18 DOI: 10.1016/j.redar.2025.501859

E. Simón Polo, I. Rubio Jiménez, N. Aguirre Ahedo, M. Sanjuán Fernández

引用次数: 0

Explorar el rol de la citometría de flujo para la evaluación de las células endoteliales en la sepsis humana: una revisión sistemática 探索细胞流量计在评估人类败血症内皮细胞中的作用：系统综述

IF 0.8 Q3 ANESTHESIOLOGY

Revista Espanola de Anestesiologia y Reanimacion

Pub Date : 2025-06-17 DOI: 10.1016/j.redar.2025.501850

M. Bardají-Carrillo , M. Martín-Fernández , A. García-Concejo , Á. Tamayo-Velasco , D. Bernardo , E. Tamayo

Introduction

Given the key role of the endothelium in organ failure secondary to sepsis, we reviewed the available literature on the use of flow cytometry (FC) to analyse endothelial cells in human sepsis.

Methods

We systematically searched PubMed and Web of Science from inception until November 2024 to identify original research articles describing the use of FC to study human endothelial cells in sepsis.

Results

A total of 395 original articles were found; 36 met the inclusion criteria. Ten studied circulating mature (CEC) or progenitor (CEPC) endothelial cells. High CEC and/or CEPC counts correlated with higher mortality; CEC numbers were increased even before the onset of shock. Twenty-six manuscripts studied the phenotype of different human microvascular endothelial cells (HMEC), and showed that expression of adhesion molecules ICAM-1, VCAM-1 and E-selectin were increased in sepsis, but there was no evidence of their association with severity or mortality.

Conclusion

High CEC and CEPC counts correlate with sepsis severity and mortality, confirming that their assessment by FC can shed some light on early sepsis diagnosis.

鉴于内皮在脓毒症继发器官衰竭中的关键作用，我们回顾了利用流式细胞术（FC）分析人类脓毒症中内皮细胞的现有文献。方法系统检索PubMed和Web of Science从成立到2024年11月，以确定描述使用FC研究脓毒症中的人内皮细胞的原始研究文章。结果共发现原创文章395篇；36例符合纳入标准。10个研究循环成熟（CEC）或祖（CEPC）内皮细胞。高CEC和/或CEPC计数与高死亡率相关；甚至在休克开始前CEC数就增加了。26篇文献研究了不同人微血管内皮细胞（HMEC）的表型，结果显示黏附分子ICAM-1、VCAM-1和e -选择素在脓毒症中表达增加，但没有证据表明它们与严重程度或死亡率相关。结论高CEC和高CEPC计数与脓毒症严重程度和死亡率相关，证实了FC对其的评估有助于脓毒症的早期诊断。

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引用次数: 0

Delirio postoperatorio en adultos mayores: un estudio de cohorte retrospectivo 老年人术后精神错乱：一项回顾性队列研究

IF 0.8 Q3 ANESTHESIOLOGY

Revista Espanola de Anestesiologia y Reanimacion

Pub Date : 2025-06-12 DOI: 10.1016/j.redar.2025.501855

J.A. Vélez-Restrepo , P.A. Betancourt-Ángel , J.D. Caicedo-Jaramillo , F.D. Casas-Arroyave

Introduction and objectives

Postoperative delirium (POD) is an adverse outcome that has garnered significant interest in perioperative medicine, particularly in older adults, due to its association with increased morbidity, mortality, and health care costs. In Colombia, this disease is under-reported due to the lack of POD diagnosis and prevention protocols. The aim of this study was to determine the incidence and potential risk factors of POD, and its association with other postoperative complications.

Materials and methods

This retrospective cohort study was performed at a tertiary care hospital. Patients over 60 years of age who underwent surgery between 2012 and 2019 were included. Random sampling was used to analyse electronic medical records to estimate the incidence of POD, risk factors, and postoperative complications within 7 days of surgery.

Results

A total of 2535 patients were evaluated. The cumulative incidence of POD was 6.0% (95% confidence interval [CI]: 5.1%-6.9%), with most cases (67%) occurring within the first 3 postoperative days. Risk factors associated with POD included a history of psychiatric disorders, preoperative opioid use, ASA (American Society of Anesthesiologists) class III/IV, vascular surgery, urgent or emergency surgery, and functional dependency. POD was also associated with higher in-hospital mortality (OR: 2.9; 95% CI: 1.66-5.07).

Conclusion

POD is common in patients aged over 60 undergoing surgery, particularly those that undergo urgent or emergency procedures and vascular surgery, who are ASA class > III, functionally dependent, and present psychiatric disorders. POD is also associated with increased postoperative morbidity and mortality.

前言和目的术后谵妄（POD）是围手术期医学中引起极大兴趣的不良后果，特别是在老年人中，因为它与发病率、死亡率和医疗费用的增加有关。在哥伦比亚，由于缺乏POD诊断和预防方案，该病的报告不足。本研究的目的是确定POD的发生率、潜在危险因素及其与其他术后并发症的关系。材料和方法本回顾性队列研究在一家三级保健医院进行。在2012年至2019年期间接受手术的60岁以上患者被纳入研究范围。采用随机抽样的方法对电子病历进行分析，估计手术后7天内POD的发生率、危险因素和术后并发症。结果共评估2535例患者。POD的累积发生率为6.0%(95%可信区间[CI]: 5.1%-6.9%)，大多数病例（67%）发生在术后前3天。与POD相关的危险因素包括精神疾病史、术前阿片类药物使用、ASA（美国麻醉医师协会）III/IV级、血管手术、紧急或紧急手术和功能依赖。POD还与较高的住院死亡率相关(OR: 2.9；95% ci: 1.66-5.07)。结论60岁以上手术患者中pod较为常见，特别是急诊或急诊手术及血管手术患者，ASA级；III，功能依赖，目前有精神障碍。POD也与术后发病率和死亡率增加有关。

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引用次数: 0

Viabilidad y aceptabilidad de una app para el seguimiento del dolor agudo postoperatorio en cirugía mayor ambulatoria 用于追踪大型门诊手术急性术后疼痛的应用程序的可行性和可接受性

IF 0.8 Q3 ANESTHESIOLOGY

Revista Espanola de Anestesiologia y Reanimacion

Pub Date : 2025-06-02 DOI: 10.1016/j.redar.2025.501854

S. Vitale, M.I. Fábregas Blanco, P. Ricós Bugeda, R. Torruella Turró, H. Fernández Fernández, E. Reñé de Antonio

Introduction

By allowing intensive monitoring of acute postoperative pain (APP), mHealth could be clinically useful in contexts with a high prevalence of moderate to severe APP.

Objectives

The primary objective was to evaluate the feasibility and acceptability of an app for monitoring APP. The secondary objectives were to describe APP during the first week of the postoperative period, to analyse factors associated with it and to assess adherence and satisfaction with analgesic treatment.

Materials and methods

Observational and prospective study in patients undergoing surgery under major ambulatory surgery regimen who reported the intensity of APP for 7 days with an app. We determined the proportions that agreed to use it and who made trajectories of APP ≥ 5 days, the pattern of use of the app and the results. Risk factors associated with APP were analyzed. Satisfaction with APP control and adherence to the analgesic regimen were assessed through surveys.

Results

A percentage of 53.4 of patients measured their APP with the app. The main reason for exclusion was technological limitations (75.1%). An uninterrupted APP trajectory of ≥ 5 days was traced in 74.4% of patients and a high prevalence of moderate to severe APP was observed, as well as a high proportion of patients who adhered little or not at all and were little or not at all satisfied with the analgesic results obtained.

Conclusions

Monitoring APP with the app used was feasible and accepted by patients. It provided clinically useful information by allowing APP trajectories to be traced and detecting high proportions of patients with moderate to severe APP, dissatisfied with the analgesic results obtained and non-compliant with analgesic guidelines.

通过加强对急性术后疼痛（APP）的监测，mHealth在中度至重度APP高发的情况下可以在临床上发挥作用。目的主要目的是评估应用程序监测APP的可行性和可接受性。次要目的是描述术后第一周的APP，分析与APP相关的因素，并评估对镇痛治疗的依从性和满意度。材料与方法观察性和前瞻性研究，在大门诊手术方案下接受手术的患者中，使用APP报告了7天的APP强度。我们确定了同意使用APP的比例，并制作了APP≥5天的轨迹，以及APP的使用模式和结果。分析与APP相关的危险因素。通过调查评估APP控制的满意度和对镇痛方案的依从性。结果53.4%的患者使用APP进行APP测量，排除的主要原因是技术限制（75.1%）。74.4%的患者有≥5天不间断的APP轨迹，中重度APP的发生率较高，且有较高比例的患者很少或根本不坚持，对获得的镇痛效果不满意或根本不满意。结论采用该APP进行APP监测是可行的，并为患者所接受。它提供了临床有用的信息，允许追踪APP轨迹，并检测出高比例的中度至重度APP患者，不满意所获得的镇痛效果和不遵守镇痛指南。

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引用次数: 0

Estimación del volumen mínimo efectivo 90% (VME90) de Ropivacaína® al 0,5% en bloqueo interescalénico ecoguiado para analgesia postoperatoria en cirugía artroscópica de hombro: un estudio prospectivo observacional de determinación de dosis y evaluación de la función diafragmática 在肩部关节镜手术中，Ropivacain®的最低有效剂量为90% （VME90）至0.5%，用于术后镇痛的超声间钙调阻滞：一项剂量测定和隔膜功能评估的前瞻性观察研究

IF 0.9 Q3 ANESTHESIOLOGY

Revista Espanola de Anestesiologia y Reanimacion

Pub Date : 2025-06-01 DOI: 10.1016/j.redar.2025.501731

B. Moreno , V. Domingo , M. Granell , J.M. Palanca , S. Selfa

Background and objectives

Ultrasound-guided ISB is the most widely-used nerve block in upper limb surgery. The aim of this study was to determine the MEV90 of 0.5% ropivacaine in ISB for analgesia in arthroscopic shoulder surgery.

Methodology

Double-blind observational post-authorization study of a medicinal product for human use. Thirty-two ASA I-III patients aged between 18 and 75 years undergoing arthroscopic shoulder surgery were recruited. We used the Dixon up-down method, whereby the dose is increased or decreased by 1 ml depending on the failure or success of the block. The initial dose was 20 ml of 0.5% ropivacaine. The study was stopped after achieving the minimum 5 negative-positive deflections. Secondary variables were the duration of the block, total analgesia consumption over the first 24 hours, and incidence of DP.

Results

The effective LA dose for postoperative analgesia in arthroscopic shoulder surgery was 6.8 ml in 50% of patients (MEV50) (90% CI: 6.234.7.465) and 7.733 ml in 90% of patients (MEV90) (90% CI: 7.393-9.109). Median sensory block duration was 772.5 minutes. The incidence of partial and total DP in QB was 34% and 41%, respectively.

Conclusion

A dose of 7.733 ml of 0.5% ropivacaine provides effective postoperative analgesia in arthroscopic shoulder surgery in 90% of patients. This lower dose reduces the likelihood of side effects.

背景与目的超声引导下的ISB是上肢手术中应用最广泛的神经阻滞。本研究的目的是确定0.5%罗哌卡因在ISB中用于关节镜肩关节手术镇痛的MEV90。方法：一种人用药品批准后的双盲观察性研究。我们招募了32名年龄在18 - 75岁之间接受肩关节镜手术的ASA I-III型患者。我们采用Dixon上下法，根据阻滞的失败或成功，剂量增加或减少1ml。初始剂量为20ml 0.5%罗哌卡因。在达到最小5个负-正偏转后停止研究。次要变量是阻滞的持续时间，前24小时的总镇痛消耗和DP的发生率。结果肩关节镜手术患者术后镇痛的有效剂量为6.8 ml (MEV50) (90% CI: 6.234.7.465), 7.733 ml (MEV90) （90% CI: 7.393-9.109）。中位感觉阻滞持续时间为772.5分钟。QB部分DP和全部DP的发生率分别为34%和41%。结论7.733 ml 0.5%罗哌卡因对90%的肩关节镜手术患者具有良好的术后镇痛效果。这种较低的剂量减少了副作用的可能性。

{"title":"Estimación del volumen mínimo efectivo 90% (VME90) de Ropivacaína® al 0,5% en bloqueo interescalénico ecoguiado para analgesia postoperatoria en cirugía artroscópica de hombro: un estudio prospectivo observacional de determinación de dosis y evaluación de la función diafragmática","authors":"B. Moreno , V. Domingo , M. Granell , J.M. Palanca , S. Selfa","doi":"10.1016/j.redar.2025.501731","DOIUrl":"10.1016/j.redar.2025.501731","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Ultrasound-guided ISB is the most widely-used nerve block in upper limb surgery. The aim of this study was to determine the MEV90 of 0.5% ropivacaine in ISB for analgesia in arthroscopic shoulder surgery.</div></div><div><h3>Methodology</h3><div>Double-blind observational post-authorization study of a medicinal product for human use. Thirty-two ASA I-III patients aged between 18 and 75 years undergoing arthroscopic shoulder surgery were recruited. We used the Dixon up-down method, whereby the dose is increased or decreased by 1ml depending on the failure or success of the block. The initial dose was 20ml of 0.5% ropivacaine. The study was stopped after achieving the minimum 5 negative-positive deflections. Secondary variables were the duration of the block, total analgesia consumption over the first 24hours, and incidence of DP.</div></div><div><h3>Results</h3><div>The effective LA dose for postoperative analgesia in arthroscopic shoulder surgery was 6.8ml in 50% of patients (MEV50) (90% CI: 6.234.7.465) and 7.733ml in 90% of patients (MEV90) (90% CI: 7.393-9.109). Median sensory block duration was 772.5minutes. The incidence of partial and total DP in QB was 34% and 41%, respectively.</div></div><div><h3>Conclusion</h3><div>A dose of 7.733ml of 0.5% ropivacaine provides effective postoperative analgesia in arthroscopic shoulder surgery in 90% of patients. This lower dose reduces the likelihood of side effects.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 6","pages":"Article 501731"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

¿Debería actualizarse la definición de dolor neuropático? 神经性疼痛的定义应该更新吗？

IF 0.9 Q3 ANESTHESIOLOGY

Revista Espanola de Anestesiologia y Reanimacion

Pub Date : 2025-06-01 DOI: 10.1016/j.redar.2025.501751

A. Alcántara Montero

引用次数: 0

Aplicación de chatbots de inteligencia artificial generativa en el campo de la anestesia 人工智能聊天机器人在麻醉领域的应用

IF 0.9 Q3 ANESTHESIOLOGY

Revista Espanola de Anestesiologia y Reanimacion

Pub Date : 2025-06-01 DOI: 10.1016/j.redar.2024.501667

A. Barroso , R. Casans

引用次数: 0

Evolución de la práctica médica: de la eminencia a la inteligencia artificial 医疗实践的演变：从卓越到人工智能

IF 0.9 Q3 ANESTHESIOLOGY

Revista Espanola de Anestesiologia y Reanimacion

Pub Date : 2025-06-01 DOI: 10.1016/j.redar.2025.501804

H.S. Manzolillo , A. Espinosa , S. Benitez , J. Ripollés-Melchor

引用次数: 0

Eficacia de la combinación del bloqueo ecoguiado del cordón espermático y el bloqueo del nervio ilioinguinal para analgesia en herniotomía inguinal pediátrica: estudio controlado aleatorizado 在儿科腹股沟疝气切开术中，回声导向精子束阻滞和腹股沟神经阻滞联合治疗镇痛的有效性：一项随机对照研究

IF 0.9 Q3 ANESTHESIOLOGY

Revista Espanola de Anestesiologia y Reanimacion

Pub Date : 2025-06-01 DOI: 10.1016/j.redar.2024.501675

E.M. Elemam, I. Abdelbaser, K. Elbahrawy, M.M. Alseoudy, S. El Kenany

Introduction and objectives

US-guided ilioinguinal nerve block (IINB) is a common analgesic regional technique in pediatric inguinal herniotomy. However, alone it could not provide complete analgesia for such surgery due to spare of the genital branch of the genitofemoral nerve (GFN) and some sympathetic fibers. Spermatic cord block (SCB) can block both of them. This study aimed to assess the analgesic effects of combining US-guided spermatic SCB and IINB in pediatric patients subjected to elective open inguinal herniotomies.

Patients and methods

A total of 50 male pediatric patients who underwent inguinal herniotomy were included in the current prospective, randomized, controlled study. Patients were randomly allocated to two groups: one group received IINB and the other received combined IINB and SCB. The number of patients who required rescue analgesia after surgery was the primary outcome parameter, whereas assessment of the intraoperative hemodynamic parameters (MAP: mean arterial pressure; HR: heart rate), total consumption of paracetamol, postoperative pain score, and occurrence of adverse events were the secondary outcome measures.

Results

The number of patients who needed rescue analgesia was significantly lower in IINB/SCB group (12%) than IINB group (41%), P = .025. The median (interquartile range) total dose of paracetamol consumption was significantly lower in the IINB/SCB group [0 (0-0)] mg/kg than in the IINB group [0 (0-15)], P = 0.02. Pain score was significantly (P < 0.05) lower in the IINB/SCB group than in the IINB group at all-time points. Both MAP and HR were significantly higher in the IINB group than in the IINB/SCB group during traction on hernial sac, P < 0.05. Occurrence of adverse events was comparable in both groups.

Conclusions

Adding SCB to IINB can provide better quality of postoperative analgesia and more stable intraoperative hemodynamics in pediatric patients undergoing inguinal hernia repair.

简介与目的美国导引髂腹股沟神经阻滞（IINB）是小儿腹股沟疝切开术中常用的局部镇痛技术。然而，由于生殖股神经（GFN）的生殖分支和一些交感神经纤维的缺失，单独使用它不能为此类手术提供完全镇痛。精索阻滞（SCB）可以阻断两者。本研究旨在评估us引导下精索SCB与IINB联合应用于择期腹股沟疝切开患儿的镇痛效果。患者和方法本前瞻性、随机、对照研究共纳入50例接受腹股沟疝切开术的儿科男性患者。患者随机分为两组：一组接受IINB治疗，另一组接受IINB和SCB联合治疗。术后需要抢救性镇痛的患者数量是主要结局参数，而术中血流动力学参数(MAP：平均动脉压；HR：心率)、扑热息痛总用量、术后疼痛评分和不良事件的发生是次要结局指标。结果IINB/SCB组需要抢救性镇痛的患者数量（12%）明显低于IINB组（41%），P = 0.025。IINB/SCB组扑热息痛总剂量中位数[0 (0-0)]mg/kg显著低于IINB组[0 (0-15)],P = 0.02。疼痛评分差异有统计学意义(P <；0.05) IINB/SCB组低于IINB组。牵疝囊时，IINB组MAP和HR均显著高于IINB/SCB组，P <；0.05. 两组不良事件的发生率具有可比性。结论在小儿腹股沟疝修补术中加入SCB可提供更好的术后镇痛质量和更稳定的术中血流动力学。

{"title":"Eficacia de la combinación del bloqueo ecoguiado del cordón espermático y el bloqueo del nervio ilioinguinal para analgesia en herniotomía inguinal pediátrica: estudio controlado aleatorizado","authors":"E.M. Elemam, I. Abdelbaser, K. Elbahrawy, M.M. Alseoudy, S. El Kenany","doi":"10.1016/j.redar.2024.501675","DOIUrl":"10.1016/j.redar.2024.501675","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>US-guided ilioinguinal nerve block (IINB) is a common analgesic regional technique in pediatric inguinal herniotomy. However, alone it could not provide complete analgesia for such surgery due to spare of the genital branch of the genitofemoral nerve (GFN) and some sympathetic fibers. Spermatic cord block (SCB) can block both of them. This study aimed to assess the analgesic effects of combining US-guided spermatic SCB and IINB in pediatric patients subjected to elective open inguinal herniotomies.</div></div><div><h3>Patients and methods</h3><div>A total of 50 male pediatric patients who underwent inguinal herniotomy were included in the current prospective, randomized, controlled study. Patients were randomly allocated to two groups: one group received IINB and the other received combined IINB and SCB. The number of patients who required rescue analgesia after surgery was the primary outcome parameter, whereas assessment of the intraoperative hemodynamic parameters (MAP: mean arterial pressure; HR: heart rate), total consumption of paracetamol, postoperative pain score, and occurrence of adverse events were the secondary outcome measures.</div></div><div><h3>Results</h3><div>The number of patients who needed rescue analgesia was significantly lower in IINB/SCB group (12%) than IINB group (41%), <em>P</em>  =0.02. Pain score was significantly (<em>P</em>  <0.05. Occurrence of adverse events was comparable in both groups.</div></div><div><h3>Conclusions</h3><div>Adding SCB to IINB can provide better quality of postoperative analgesia and more stable intraoperative hemodynamics in pediatric patients undergoing inguinal hernia repair.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 6","pages":"Article 501675"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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