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Comentarios sobre el artículo «Mean airway pressure as a parameter of lung-protective and heart-protective ventilation», de Placenti A, Fratebianchi F 评论:sobre el artículo«平均气道压力作为肺保护和心脏保护通气的参数»,de Placenti a, Fratebianchi F
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2025-06-01 DOI: 10.1016/j.redar.2025.501734
M. de la Matta, D. López-Herrera
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引用次数: 0
Bloqueo del plano serrato intercostal frente al bloqueo del cuadrado lumbar posterior en nefrectomía laparoscópica: estudio aleatorizado, controlado, doble ciego 腹腔镜肾直肠切除术中肋间脊面阻塞与后腰方阻塞:随机对照双盲研究
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2025-06-01 DOI: 10.1016/j.redar.2025.501728
M.T. Fernandez Martin , M.G. Matesanz , J. Andres , H. Muñoz , M.F. Muñoz , A. Fadrique , P. Castillo , P. Casas , S. Lopez

Background

Even though laparoscopic nephrectomy improves the quality of postoperative recovery, it still causes moderate to severe pain. Our objective was to determine whether serratus intercostal plane block (SIPB) was noninferior to posterior quadratus lumborum block (QLB) in terms of pain control and quality of recovery.

Methods

This multicentre, controlled, randomized, blinded study had a sample size of 120 patients who were randomly assigned to SIPB, QLB, and control groups prior to scheduled laparoscopic nephrectomy. We collected the following variables: postoperative dynamic pain scores at 0, 6, 12, and 24 hours, postoperative quality of recovery (QoR15), and total opioid consumption (fentanyl and morphine).

Results

Our results show that SIPB was non-inferior to QLB with regard to the primary endpoint (NRS 0.4/0.9) and quality of recovery (QoR15 112.7/106.85) (P .27). Opioid consumption (fentanyl P .37 and morphine P .9) was similar in the SIPB and QLB groups, and both groups were superior to controls in terms of intraoperative fentanyl consumption (P .001) and pain control (P <.001).

Conclusions

SIPB and QLB showed adequate postoperative pain control, good quality of recovery and lower fentanyl consumption, especially compared to the control group.
尽管腹腔镜肾切除术提高了术后恢复的质量,但仍会引起中度至重度疼痛。我们的目的是确定在疼痛控制和恢复质量方面,锯肌肋间平面阻滞(SIPB)是否优于腰后方肌阻滞(QLB)。方法本研究是一项多中心、随机、盲法、对照研究,共纳入120例患者,随机分为腹腔镜肾切除术前SIPB组、QLB组和对照组。我们收集了以下变量:术后0、6、12和24小时的动态疼痛评分,术后恢复质量(QoR15)和阿片类药物总用量(芬太尼和吗啡)。结果SIPB在主要终点(NRS 0.4/0.9)和恢复质量(QoR15 112.7/106.85)方面均不低于QLB (P .27)。阿片类药物用量(芬太尼P .37,吗啡P .9)在SIPB组和QLB组中相似,两组在术中芬太尼用量(P .001)和疼痛控制(P < 001)方面均优于对照组。结论与对照组相比,ssipb和QLB术后疼痛控制良好,恢复质量好,芬太尼用量低。
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引用次数: 0
Intubación traqueal con videolaringoscopia: superando la barrera del lenguaje 气管插管用视频鼻镜:克服语言障碍
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2025-06-01 DOI: 10.1016/j.redar.2024.501676
M.A. Fernández-Vaquero , A.A.J. van Zundert , M.A. Gómez-Ríos
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引用次数: 0
Rotura traqueal consecuencia de hematoma intramural aórtico sobreinfectado en prótesis de aorta ascendente 升主动脉假体上的主动脉腔内血肿过度感染导致气管破裂
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2025-06-01 DOI: 10.1016/j.redar.2024.06.005
E. Pereda González, A. Cervera Puchades, M.J. Hernández-Cádiz, J. Moreno Pachón, J. de Andrés Ibáñez
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引用次数: 0
Monitorización de la nocicepción mediante índice NoL y su implicación en la reducción de las complicaciones en cirugía abdominal laparoscópica (estudio SIMONE): protocolo de un estudio prospectivo, multicéntrico, observacional de cohortes 使用NoL指数监测伤害及其在减少腹腔镜腹部手术并发症方面的作用(SIMONE研究):一项前瞻性、多中心、观察队列的研究方案
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2025-06-01 DOI: 10.1016/j.redar.2025.501729
A.M. Pascual-Bellosta , C. Aragón-Benedí , S.M. Ortega-Lucea , L. Mínguez-Braulio , M. Buey-Aguilar , A. Abad-Gurumeta , E. Tamayo-Gómez , J. Martinez-Ubieto , Grupo de Estudio SIMONE

Background and objectives

Nociception monitoring allows for the titration of opioid drugs in the intraoperative period in order to avoid under- and overdosing of these drugs and their side effects in the patient's postoperative period. For this reason, a study has been designed with the aim of establishing whether the usefulness of the NoL® (Nociception Level) device for adequate intraoperative nociception monitoring can reduce postoperative complications.

Material and methods

Multicentre, observational, prospective cohort study that will include patients who underwent laparoscopic abdominal surgery under balanced general anaesthesia during one year in different hospital centres in order to assess the incidence of early and late postoperative complications and their relationship with the monitoring of nociception studied through the NoL device. Intraoperative pain management will be based on NoL values (visible NoL group) or hemodynamic parameters according to usual clinical practice (non-visible NoL group).

Results

Approval has been obtained from the Autonomous Research Ethics Committee of Aragon (C.I. EPA23/026, 19 April 2023). SIMONE study was registered at www.clinicaltrials.gov on 30 May 2024 (Identifier: NCT06437743).

Conclusions

The overall data will be published in peer-reviewed journals. The relevance of the SIMONE study lies in being the first nationwide to comprehensively evaluate opioid dosing, postoperative pain, early and late postoperative complications, and the length of hospital stay. A significant reduction in the incidence of postoperative complications such as nausea and vomiting is expected in the group with visible NoL monitoring.
背景和目的:术中对阿片类药物进行痛觉监测,以避免患者术后阿片类药物的剂量不足和过量及其副作用。因此,我们设计了一项研究,目的是确定NoL®(痛觉水平)装置在术中进行足够的痛觉监测是否可以减少术后并发症。材料和方法一项多中心、观察性、前瞻性队列研究,将包括在不同医院中心一年内在平衡全身麻醉下接受腹腔镜腹部手术的患者,以评估术后早期和晚期并发症的发生率及其与通过NoL装置研究的伤害感觉监测的关系。术中疼痛处理依据NoL值(可见NoL组)或临床常规血流动力学参数(不可见NoL组)。已获得阿拉贡自治研究伦理委员会(C.I. epa23 / 026,2023年4月19日)的批准。SIMONE研究于2024年5月30日在www.clinicaltrials.gov注册(标识符:NCT06437743)。结论全部数据将发表在同行评议的期刊上。SIMONE研究的相关性在于,它是全国首个综合评估阿片类药物剂量、术后疼痛、术后早期和晚期并发症以及住院时间的研究。在可见NoL监测组中,术后并发症如恶心和呕吐的发生率有望显著降低。
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引用次数: 0
Efecto de la cafeína en la frecuencia respiratoria, el tiempo de recuperación y la actividad de onda cerebral durante la emergencia de la anestesia con sevoflurano en ratas 大鼠在紧急用硫氟烷麻醉时,咖啡因对呼吸频率、恢复时间和脑电波活动的影响
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2025-06-01 DOI: 10.1016/j.redar.2025.501730
B.M. Çam , H. Topçu , E.S. Tiryaki , G. Arslan

Objective

To determine whether caffeine affects the respiratory rate, recovery time and brain slow-wave (theta and delta) activities during the recovery from sevoflurane anesthesia in rats.

Methods

Male Sprague-Dawley rats (n = 16) were randomly divided into 2 groups: control (saline) and caffeine(75 mg/kg). After tripolar electrode implantation, rats were placed in an anesthesia chamber and brain electrocorticographic wave activities began to be recorded. Anesthesia induction was provided with sevoflurane at 4% concentration (4 L/min O2) for 5 min and when all of the rats became unconscious, sevoflurane concentration was reduced to 3% (4 L/min O2) for anesthesia maintenance. Saline or caffeine was intraperitoneally injected 10 min before discontinuing the anesthesia. After the sevoflurane was cut off, the rats were removed from the gas-tight box and the durations of the respiratory rate, the tail clamp and the righting reflex (full-recovery) were observed and noted. Theta and delta wave numbers and amplitude (above basal activity) as well as the number of theta oscillations were calculated from electrocorticographic recordings.

Results

Caffeine administration increased the respiratory rate during sevoflurane anesthesia; however, no significant difference was seen compared to the control group during the full recovery period. The durations of the tail clamp and the righting reflex, theta oscillations, and slow-wave number and amplitude were decreased with the injection of caffeine.

Conclusions

Acute administration of caffeine accelerates the recovery from sevoflurane anesthesia by affecting the central nervous system. Considering that prolongation of the recovery period from anesthesia increases postoperative delirium, intraoperative caffeine use may reduce risks.
目的观察咖啡因对七氟醚麻醉后大鼠呼吸频率、恢复时间和脑慢波活动的影响。方法16只雄性sd大鼠随机分为对照组(生理盐水)和咖啡因组(75 mg/kg)。三极电极植入后,将大鼠置于麻醉室,记录脑皮质电波活动。麻醉诱导用浓度为4% (4 L/min O2)的七氟醚持续5min,待大鼠全部昏迷后,将七氟醚浓度降至3% (4 L/min O2)维持麻醉。停止麻醉前10分钟腹腔注射生理盐水或咖啡因。切断七氟醚后,将大鼠从气密箱中取出,观察并记录呼吸频率、夹尾持续时间和翻正反射(完全恢复)持续时间。θ波和δ波的数量和振幅(高于基础活动)以及θ波振荡的数量是根据皮质电记录计算的。结果七氟醚麻醉时,给药组呼吸频率增高;然而,在整个恢复期,与对照组相比没有明显差异。注射咖啡因后,大鼠尾夹钳持续时间、翻正反射时间、θ波振荡时间、慢波数量和振幅均明显减少。结论急性给药咖啡因可通过影响中枢神经系统加速七氟醚麻醉后的恢复。考虑到麻醉恢复期的延长会增加术后谵妄,术中使用咖啡因可能会降低风险。
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引用次数: 0
Suzetrigina como analgésico no opioide: entre la necesidad y la evidencia científica 苏曲霉素作为非阿片类止痛药:从必要性到科学证据
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2025-05-28 DOI: 10.1016/j.redar.2025.501858
A. Alcántara Montero
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引用次数: 0
Lesión renal aguda postoperatoria en cirugía mayor abdominal. Utilidad del biomarcador urinario [TIMP-2] × [IGFBP7] (NephroCheck®) 腹部大手术中的急性术后肾脏损伤。尿液生物标志物[TIMP-2] × [IGFBP7] (NephroCheck®)的效用
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2025-05-23 DOI: 10.1016/j.redar.2025.501853
A. Lara-Jiménez , P. Monedero , G. Echarri

Background

The urinary biomarker [TIMP-2] × [IGFBP7] enables the prediction of postoperative acute kidney injury (PO-AKI). Our study aimed to assess the incidence of PO-AKI in high-risk patients undergoing major abdominal surgery and to evaluate the impact of implementing KDIGO renal optimization measures in those with renal stress identified by [TIMP-2] × [IGFBP7].

Materials and methods

This was a prospective study including 182 patients who underwent major abdominal surgery. Perioperative data, [TIMP-2] × [IGFBP7] levels, and the implementation of KDIGO renal protection strategies in the ICU were collected. Predictors of PO-AKI were identified through multivariate analysis.

Results

The overall incidence of PO-AKI was 25.3%, reaching 42.7% in ICU patients. [TIMP-2] × [IGFBP7] showed moderate predictive ability (AUROC = .74), with a PO-AKI incidence of 47.5% in patients with elevated levels. Despite the implementation of KDIGO measures in the ICU, the incidence of PO-AKI in patients with elevated [TIMP-2] × [IGFBP7] was 65.6%. In multivariate analysis, the main predictors of PO-AKI were elevated [TIMP-2] × [IGFBP7] (OR = 6.3; 95% CI: 2.6-15.6; P < .001), male sex (OR = 6.1; 95% CI: 1.9-19.6; P = .002), and ICU admission (OR = 4.5; 95% CI: 1.5-13.6; P = .009).

Conclusions

PO-AKI is common after major abdominal surgery, particularly in ICU patients. The [TIMP-2] × [IGFBP7] biomarker allows for early identification of at-risk patients, although the implementation of KDIGO measures in the ICU did not significantly reduce its incidence.
尿生物标志物[TIMP-2] × [IGFBP7]能够预测术后急性肾损伤(PO-AKI)。本研究旨在评估接受腹部大手术的高危患者PO-AKI的发生率,并评估实施KDIGO肾脏优化措施对[TIMP-2] × [IGFBP7]识别的肾应激患者的影响。材料和方法这是一项前瞻性研究,包括182例接受腹部大手术的患者。收集围手术期数据、[TIMP-2] × [IGFBP7]水平及KDIGO肾保护策略在ICU的实施情况。通过多变量分析确定PO-AKI的预测因素。结果PO-AKI总发生率为25.3%,ICU患者发生率为42.7%。[TIMP-2] × [IGFBP7]具有中等预测能力(AUROC = .74),升高的患者PO-AKI发生率为47.5%。尽管在ICU实施了KDIGO措施,但在[TIMP-2] × [IGFBP7]升高的患者中,PO-AKI的发生率为65.6%。在多因素分析中,PO-AKI的主要预测因子为[TIMP-2] × [IGFBP7]升高(OR = 6.3;95% ci: 2.6-15.6;P & lt;.001),男性(OR = 6.1;95% ci: 1.9-19.6;P = .002), ICU住院率(OR = 4.5;95% ci: 1.5-13.6;p = .009)。结论spoo - aki在腹部大手术后较为常见,尤其是在ICU患者中。[TIMP-2] × [IGFBP7]生物标志物允许早期识别高危患者,尽管在ICU实施KDIGO措施并没有显著降低其发生率。
{"title":"Lesión renal aguda postoperatoria en cirugía mayor abdominal. Utilidad del biomarcador urinario [TIMP-2] × [IGFBP7] (NephroCheck®)","authors":"A. Lara-Jiménez ,&nbsp;P. Monedero ,&nbsp;G. Echarri","doi":"10.1016/j.redar.2025.501853","DOIUrl":"10.1016/j.redar.2025.501853","url":null,"abstract":"<div><h3>Background</h3><div>The urinary biomarker [TIMP-2]<!--> <!-->×<!--> <!-->[IGFBP7] enables the prediction of postoperative acute kidney injury (PO-AKI). Our study aimed to assess the incidence of PO-AKI in high-risk patients undergoing major abdominal surgery and to evaluate the impact of implementing KDIGO renal optimization measures in those with renal stress identified by [TIMP-2]<!--> <!-->×<!--> <!-->[IGFBP7].</div></div><div><h3>Materials and methods</h3><div>This was a prospective study including 182 patients who underwent major abdominal surgery. Perioperative data, [TIMP-2]<!--> <!-->×<!--> <!-->[IGFBP7] levels, and the implementation of KDIGO renal protection strategies in the ICU were collected. Predictors of PO-AKI were identified through multivariate analysis.</div></div><div><h3>Results</h3><div>The overall incidence of PO-AKI was 25.3%, reaching 42.7% in ICU patients. [TIMP-2]<!--> <!-->×<!--> <!-->[IGFBP7] showed moderate predictive ability (AUROC<!--> <!-->=<!--> <!-->.74), with a PO-AKI incidence of 47.5% in patients with elevated levels. Despite the implementation of KDIGO measures in the ICU, the incidence of PO-AKI in patients with elevated [TIMP-2]<!--> <!-->×<!--> <!-->[IGFBP7] was 65.6%. In multivariate analysis, the main predictors of PO-AKI were elevated [TIMP-2]<!--> <!-->×<!--> <!-->[IGFBP7] (OR<!--> <!-->=<!--> <!-->6.3; 95%<!--> <!-->CI: 2.6-15.6; <em>P</em> <!-->&lt;<!--> <!-->.001), male sex (OR<!--> <!-->=<!--> <!-->6.1; 95%<!--> <!-->CI: 1.9-19.6; <em>P</em> <!-->=<!--> <!-->.002), and ICU admission (OR<!--> <!-->=<!--> <!-->4.5; 95%<!--> <!-->CI: 1.5-13.6; <em>P</em> <!-->=<!--> <!-->.009).</div></div><div><h3>Conclusions</h3><div>PO-AKI is common after major abdominal surgery, particularly in ICU patients. The [TIMP-2]<!--> <!-->×<!--> <!-->[IGFBP7] biomarker allows for early identification of at-risk patients, although the implementation of KDIGO measures in the ICU did not significantly reduce its incidence.</div></div>","PeriodicalId":46479,"journal":{"name":"Revista Espanola de Anestesiologia y Reanimacion","volume":"72 7","pages":"Article 501853"},"PeriodicalIF":0.8,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144722121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Actualización en el tratamiento del dolor neuropático del Grupo de Interés Especial en Dolor Neuropático de la Asociación Internacional para el Estudio del Dolor 国际疼痛研究协会神经性疼痛特别关注小组神经性疼痛治疗的最新情况
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2025-05-22 DOI: 10.1016/j.redar.2025.501856
A. Alcántara Montero
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引用次数: 0
Variabilidad de la frecuencia cardiaca para la evaluación de la capacidad funcional en programas de rehabilitación multimodal en cirugía del adulto: Protocolo Estudio PreANI 多模式成人手术康复方案中功能能力评估的心率变异性:ANI前研究方案
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2025-05-12 DOI: 10.1016/j.redar.2025.501849
C. Aragón-Benedí , S. Ortega-Lucea , A. Pascual-Bellosta , M. Corcoy-Bidasolo , J. Longas-Vailen , J. Martinez-Ubieto , Grupo de Investigación Estudio PreANI

Background and objectives

Despite the implementation of multimodal rehabilitation programs, postoperative complications are common in some surgeries, and patient recovery is not as rapid as expected. This study was designed to evaluate whether postoperative outcomes can be improved by assessing preoperative functional reserve and frailty on the basis of heart rate variability, specifically energy and the ANIm value, in patients following prehabilitation programs.

Material and method

Prospective, observational cohort study that will include patients undergoing colorectal oncology surgery within a multimodal rehabilitation program. Patients will be monitored with the ANI device at 2 time points: initial (first pre-anaesthesia consultation, 4 weeks before surgery) and second consultation (1 week before surgery). Data will be collected on heart rate variability, energy, and ANIm values, cardiopulmonary exercise test scores, and other parameters.

Results

We will analyse the correlation between heart rate variability indices and current functional assessment parameters, physiological reserve, and frailty (ASA scale, 6-minute walk test, MUST scale, and Clinical Frailty Scale). Our hypothesis is that higher energy levels will correlate with better postoperative outcomes, fewer complications, and shorter hospital stays. Statistical analysis will respect all principles of confidentiality and privacy. The results will be published in peer-reviewed journals.

Conclusions

This study aims to provide a new tool for assessing frailty and functional reserve in surgical patients as a means of improving prehabilitation programs and postoperative outcomes.
背景与目的尽管实施了多模式康复方案,但术后并发症在一些手术中很常见,患者的恢复并不像预期的那样快。本研究旨在通过评估术前功能储备和虚弱程度(基于心率变异性,特别是能量和ANIm值)来评估患者在康复前的预后是否可以得到改善。材料和方法前瞻性、观察性队列研究,将包括在多模式康复计划中接受结直肠肿瘤手术的患者。患者将在2个时间点使用ANI设备进行监测:初始(第一次麻醉前会诊,术前4周)和第二次会诊(术前1周)。将收集心率变异性、能量和animm值、心肺运动测试分数和其他参数的数据。结果我们将分析心率变异性指标与当前功能评估参数、生理储备和虚弱(ASA量表、6分钟步行测试、MUST量表和临床虚弱量表)之间的相关性。我们的假设是,更高的能量水平与更好的术后结果、更少的并发症和更短的住院时间相关。统计分析将尊重所有保密和隐私原则。研究结果将发表在同行评议的期刊上。结论本研究旨在为评估手术患者的虚弱和功能储备提供一种新的工具,作为改善康复计划和术后预后的手段。
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引用次数: 0
期刊
Revista Espanola de Anestesiologia y Reanimacion
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