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Cómo un único caso de delirio perioperatorio marca la diferencia 一例围手术期谵妄病例如何带来改变
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.redar.2024.01.003

This report describes how postoperative delirium in an elderly man during the COVID-19 pandemic led to a serious event involving a central venous catheter. Delirium is a common cause of perioperative morbidity and mortality, and is characterised by an alteration in consciousness and perception and a reduced ability to focus, sustain, or shift attention. The event was analysed by a multidisciplinary committee, which developed a risk stratification delirium protocol in order to prevent similar events in the future.

本报告描述了在 COVID-19 大流行期间,一名老人的术后谵妄如何导致涉及中心静脉导管的严重事件。谵妄是围手术期发病和死亡的常见原因,其特征是意识和感知发生改变,集中、维持或转移注意力的能力下降。多学科委员会对该事件进行了分析,并制定了谵妄风险分层协议,以防止今后发生类似事件。
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引用次数: 0
Estimulación del ganglio de Gasser para dolor neuropático del trigémino refractario 刺激加瑟神经节治疗难治性三叉神经痛
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.redar.2024.01.007

Background and objective

Painful trigeminal neuropathy is a complex clinical entity due to its severity and refractoriness to pharmacological and interventional management. We describe our experience in treating refractory painful trigeminal neuropathy (RPTN) with Gasserian ganglion stimulation (GGS).

Materials and methods

Six patients with RPTN were treated with GGS in our unit between 2019 and 2022. The following data were collected: socio-demographic characteristics, triggering event, duration of the disease and treatment received prior to surgery, pre- and post-intervention visual analogue scale score, follow-up time, and pre- and post-intervention functionality and quality of life.

Results

All patients were women who had received aggressive first-, second-, and third-line pharmacological, non-pharmacological, and interventional management before being referred for GGS. Patients reported a 50-72% decrease in pain on visual analogue scale and improved functionality during follow-up.

Conclusions

GGS is a promising therapeutic alternative for patients with RPTN. Although the initial outcomes and experience are encouraging, RPTN is recommended on the basis of safety, reproducibility, and trends observed in clinical practice.

背景和目的疼痛性三叉神经病变是一种复杂的临床实体,因为其严重性和对药物和介入治疗的耐受性。我们介绍了本单位在 2019 年至 2022 年期间使用 GGS 治疗难治性疼痛性三叉神经病(RPTN)的经验。收集了以下数据:社会人口学特征、诱发事件、病程和术前接受的治疗、干预前后的视觉模拟量表评分、随访时间以及干预前后的功能和生活质量。结果所有患者均为女性,在转诊接受 GGS 治疗之前,她们已接受了积极的一线、二线和三线药物、非药物和介入治疗。随访期间,患者的视觉模拟量表显示疼痛减轻了 50%-72% 并改善了功能。虽然最初的结果和经验令人鼓舞,但基于安全性、可重复性和临床实践中观察到的趋势,建议采用 RPTN。
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引用次数: 0
Sarcopenia medida por tomografía como predictor de morbimortalidad en cirugía torácica, una cohorte retrospectiva 通过断层扫描测量的 "肌肉疏松症 "可预测胸外科手术的发病率和死亡率,这是一项回顾性队列研究。
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.redar.2023.08.006
V. Martínez Hurtado , C.D. Ramírez Luján , C.A. Pardo Peña , F.D. Casas Arroyave , A. García

Background

Sarcopenia has been identified as a risk factor for perioperative adverse events. Several studies have shown that tomographic assessment of muscle mass can be an appropriate indicator of sarcopenia associated with morbidity and mortality. The aim of the study was to determine the association between height-adjusted area of the pectoral and erector spinae muscles (haPMA and haESA) and perioperative morbidity and mortality in thoracic surgery.

Methods

Retrospective cohort study. Measurement of muscle areas was performed by tomography. The outcomes were 30-day mortality and postoperative morbidity. The discriminative capacity of the muscle areas was evaluated with an analysis of ROC curves and the Youden index was used to establish a cut-off point. The raw morbidity and mortality risk was determined and adjusted for potential confounders.

Results

A total of 509 patients taken to thoracic surgery were included. The incidence of 30-day mortality was 7.3%. An association was found between muscle areas and 30-day mortality and pneumonia, with adequate discriminative power for mortality (AUC 0.68 for haPMA and 0.67 for haESA). An haPMA less than 10 and haESA less than 8.5 cm2/m2 were identified as a risk factor for 30-day mortality with an adjusted OR of 2.34 (95%CI 1.03 – 5.15) and 2.22 (95%CI 1.10 – 6.04) respectively.

Conclusions

Sarcopenia, defined as low muscle area in the pectoral and erector spinae muscles, is associated with increased morbidity and mortality in patients undergoing thoracic surgery.

背景肌肉疏松症已被确定为围术期不良事件的风险因素。多项研究表明,肌肉质量断层扫描评估可作为与发病率和死亡率相关的肌肉疏松症的适当指标。该研究旨在确定胸廓手术中胸肌和竖脊肌的身高调整面积(haPMA 和 haESA)与围术期发病率和死亡率之间的关系。通过断层扫描测量肌肉面积。研究结果为 30 天死亡率和术后发病率。通过 ROC 曲线分析评估了肌肉面积的判别能力,并使用尤登指数确定了分界点。结果 共纳入了 509 名接受胸外科手术的患者。30天死亡率为7.3%。研究发现,肌肉面积与 30 天死亡率和肺炎之间存在关联,对死亡率有足够的鉴别力(haPMA 的 AUC 为 0.68,haESA 为 0.67)。haPMA 小于 10 和 haESA 小于 8.5 cm2/m2 被确定为 30 天死亡率的风险因素,调整后 OR 分别为 2.34(95%CI 1.03 - 5.15)和 2.22(95%CI 1.10 - 6.04)。
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引用次数: 0
El riesgo de hipertermia maligna es bajo en casos de neuromiotonía 神经肌张力障碍患者发生恶性高热的风险较低。
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.redar.2023.07.007
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引用次数: 0
Hipotensión postoperatoria: ¿es seguro el uso intraoperatorio de dexmedetomidina en pacientes frágiles? 术后低血压:术中使用右美托咪定对体弱患者安全吗?
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.redar.2024.01.001
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引用次数: 0
Lavado pulmonar total bilateral bajo soporte con membrana de oxigenación extracorpórea veno-venosa en un caso de proteinosis alveolar grave 在静脉体外膜氧合支持下对一例严重肺泡蛋白沉积症患者进行双侧全肺灌洗。
IF 0.9 Q3 ANESTHESIOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.redar.2023.07.005

We present the case of a 71-year-old woman with severe bilateral primary alveolar proteinosis admitted for bilateral whole lung lavage (WLL) with a double-lumen endotracheal tube. She had a cardiac arrest of respiratory origin during the procedure and recovered after one minute of advanced resuscitation. A second LLP was scheduled under respiratory support with veno-venous extracorporeal membrane oxygenation (VV-ECMO). During this second WLL the patient was completely VV-ECMO-dependent, and the procedure was successfully completed. She was gradually weaned over the next 48 hours. The patient was finally discharged after clinical improvement and home oxygen therapy was discontinued. WLL is the treatment of choice for severe cases of alveolar proteinosis. In rare cases the intervention may be poorly tolerated due to the degree of lung involvement. This case illustrates how VV-ECMO support is an option that may benefit this subgroup of at-risk patients.

我们为您介绍一例患有严重双侧原发性肺泡蛋白沉积症的 71 岁女性病例,她入院时使用双腔气管插管进行双侧全肺灌洗(WLL)。她在手术过程中呼吸心跳骤停,经过一分钟的高级复苏后恢复。在静脉体外膜肺氧合(VV-ECMO)呼吸支持下,安排了第二次 LLP。在第二次 LLP 期间,患者完全依赖 VV-ECMO,手术顺利完成。在接下来的 48 小时内,她逐渐断奶。患者最终在临床好转后出院,并停止了家庭氧疗。肺泡蛋白沉积症是严重肺泡蛋白沉积症的首选治疗方法。在极少数病例中,由于肺部受累的程度不同,患者对这种治疗方法的耐受性可能很差。本病例说明了 VV-ECMO 支持是如何使这部分高危患者受益的。
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引用次数: 0
Masa intracardíaca 心内肿块
IF 1.3 Q3 Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.redar.2023.02.004
J. Llau García, J. Moreno Pachón, E. Mateo Rodríguez, J. de Andrés Ibáñez
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引用次数: 0
Diseños de formación en anestesia en Europa: estudio basado en una encuesta realizado por el comité de residentes de la European Society of Anaesthesiology and Intensive Care (ESAIC) 欧洲的麻醉培训设计:欧洲麻醉学和重症监护学会(ESAIC)住院医师培训委员会开展的一项调查研究。
IF 1.3 Q3 Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.redar.2023.08.005
I. Abramovich , I. Crisan , D. Sobreira Fernandes , S. De Hert , A. Lukic , G. Norte , B. Matias , M. Majić , J. Berger-Estilita

Background

Anaesthesiology training programs in Europe vary in duration, content, and requirements for completion. This survey-based study conducted by the Trainees Committee of the European Society of Anaesthesiology and Intensive Care explores current anaesthesia training designs across Europe.

Methods

Between May and July 2018, we sent a 41-item online questionnaire to all National Trainee Representatives, members of the National Anaesthesiologists Societies Committee, and Council Representatives of the European Society of Anaesthesiology and Intensive Care (ESAIC) of all member countries. We cross-validated inconsistent data with different country representatives.

Results

Forty-three anaesthesiologists from the 39 associated ESAIC countries completed the questionnaire. Results showed considerable variability in teaching formats, frequency of teaching sessions during training, and differences in assessments made during and at the end of training. The reported duration of training was 60 months in 59% (n = 23) of participating countries, ranging from 24 months in Russia and Ukraine to 84 months in the UK.

Conclusion

This study shows the significant differences in anaesthesiology training formats across Europe, and highlights the importance of developing standardised training programs to ensure a consistent level of training and to improve patient safety. This study provides valuable insights into European anaesthesia training, and underlines the need for further research and collaboration to improve requirements.

背景欧洲的麻醉学培训项目在持续时间、内容和完成要求方面各不相同。欧洲麻醉学和重症监护学会受训人员委员会开展的这项基于调查的研究探讨了欧洲各地目前的麻醉培训设计。方法2018年5月至7月期间,我们向所有成员国的所有国家受训人员代表、国家麻醉医师学会委员会成员以及欧洲麻醉学和重症监护学会(ESAIC)理事会代表发送了一份包含41个项目的在线问卷。我们与不同国家的代表对不一致的数据进行了交叉验证。结果来自欧洲麻醉与重症监护学会 39 个相关国家的 43 名麻醉医师完成了问卷调查。结果显示,教学形式、培训期间教学课程的频率以及培训期间和培训结束时的评估差异很大。59%的参与国(n = 23)报告的培训时间为 60 个月,从俄罗斯和乌克兰的 24 个月到英国的 84 个月不等。本研究为欧洲麻醉培训提供了宝贵的见解,并强调了进一步研究和合作以提高要求的必要性。
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引用次数: 0
Presión media de la vía aérea: ¿parámetro integrador de ventilación pulmonar y circulatoria protectoras? 平均气道压力:保护性肺通气和循环通气的综合参数?
IF 1.3 Q3 Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.redar.2024.01.006
A. Placenti, F. Fratebianchi

Mean airway pressure (MAP) is the mean pressure generated in the airway during a single breath (inspiration + expiration), and is displayed on most anaesthesia and intensive care ventilators. This parameter, however, is not usually monitored during mechanical ventilation because it is poorly understood and usually only used in research. One of the main determinants of MAP is PEEP. This is because in respiratory cycles with an I:E ratio of 1:2, expiration is twice as long as inspiration. Although MAP can be used as a surrogate for mean alveolar pressure, these parameters differ considerably in some situations. Recently, MAP has been shown to be a useful prognostic factor for respiratory morbidity and mortality in mechanically ventilated patients of various ages. Low MAP has been associated with a lower incidence of 90-day mortality, shorter ICU stay, and shorter mechanical ventilation time. MAP also affects haemodynamics: there is evidence of a causal relationship between high MAP and low perfusion index, both of which are associated with poor prognosis in mechanically ventilated patients. Elevated MAP values have also been associated with high central venous pressure and lactate, which are indicative of ventilator-associated right ventricular failure and tissue hypoperfusion, respectively. MAP, therefore, is an important parameter to measure in clinical practice. The aim of this review has been to identify the determinants of MAP, the pros and cons of using MAP instead of traditional protective ventilation parameters, and the evidence that supports the use of MAP in clinical practice.

平均气道压 (MAP) 是指单次呼吸(吸气 + 呼气)过程中气道内产生的平均压力,大多数麻醉和重症监护呼吸机都会显示该值。然而,在机械通气过程中通常不会对这一参数进行监测,因为人们对其了解甚少,而且通常仅用于研究。PEEP 是决定 MAP 的主要因素之一。这是因为在 I:E 比为 1:2 的呼吸周期中,呼气时间是吸气时间的两倍。虽然 MAP 可用作平均肺泡压的替代物,但在某些情况下这些参数会有很大差异。最近的研究表明,平均肺泡压是不同年龄机械通气患者呼吸系统发病率和死亡率的有效预后因素。低 MAP 与较低的 90 天死亡率、较短的重症监护室住院时间和较短的机械通气时间有关。血压也会影响血液动力学:有证据表明,高血压和低灌注指数之间存在因果关系,两者都与机械通气患者的不良预后有关。MAP 值升高还与中心静脉压和乳酸升高有关,而中心静脉压和乳酸升高分别表明呼吸机相关性右心室衰竭和组织灌注不足。因此,MAP 是临床实践中需要测量的一个重要参数。本综述旨在确定 MAP 的决定因素、使用 MAP 代替传统保护性通气参数的利弊以及支持在临床实践中使用 MAP 的证据。
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引用次数: 0
Manejo de la anemia periquirúrgica en cirugía electiva. Conclusiones y recomendaciones según metodología Delphi-UCLA 择期手术围手术期贫血的管理。根据 Delphi-UCLA 方法得出的结论和建议。
IF 1.3 Q3 Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.redar.2023.11.008
V. Moral , A. Abad Motos , C. Jericó , M.L. Antelo Caamaño , J. Ripollés Melchor , E. Bisbe Vives , J.A. García Erce , en nombre del Panel de expertos seleccionado para la realización del ejercicio Delphi

Introduction

Preoperative anemia affects approximately one third of surgical patients. It increases the risk of blood transfusion and influences short- and medium-term functional outcomes, increases comorbidities, complications and costs. The «Patient Blood Management» (PBM) programs, for integrated and multidisciplinary management of patients, are considered as paradigms of quality care and have as one of the fundamental objectives to correct perioperative anemia. PBM has been incorporated into the schemes for intensified recovery of surgical patients: the recent Enhanced Recovery After Surgery 2021 pathway (in Spanish RICA 2021) includes almost 30 indirect recommendations for PBM.

Objective

To make a consensus document with RAND/UCLA Delphi methodology to increase the penetration and priority of the RICA 2021 recommendations on PBM in daily clinical practice.

Material and methods

A coordinating group composed of 6 specialists from Hematology-Hemotherapy, Anesthesiology and Internal Medicine with expertise in anemia and PBM was formed. A survey was elaborated using Delphi RAND/UCLA methodology to reach a consensus on the key areas and priority professional actions to be developed at the present time to improve the management of perioperative anemia. The survey questions were extracted from the PBM recommendations contained in the RICA 2021 pathway. The development of the electronic survey (Google Platform) and the management of the responses was the responsibility of an expert in quality of care and clinical safety.

Participants were selected by invitation from speakers at AWGE-GIEMSA scientific meetings and national representatives of PBM-related working groups (Seville Document, SEDAR HTF section and RICA 2021 pathway participants).

In the first round of the survey, the anonymized online questionnaire had 28 questions: 20 of them were about PBM concepts included in ERAS guidelines (2 about general PBM organization, 10 on diagnosis and treatment of preoperative anemia, 3 on management of postoperative anemia, 5 on transfusion criteria) and 8 on pending aspects of research. Responses were organized according to a 10-point Likter scale (0: strongly disagree to 10: strongly agree). Any additional contributions that the participants considered appropriate were allowed. They were considered consensual because all the questions obtained an average score of more than 9 points, except one (question 14).

The second round of the survey consisted of 37 questions, resulting from the reformulation of the questions of the first round and the incorporation of the participants’ comments. It consisted of 2 questions about general organization of PBM programme, 15 questions on the diagnosis and treatment of preoperative anemia; 3 on the management of postoperative anemia, 6 on transfusional criteria and finally 11 questions on aspects pending od future investigations.

Stati

导言术前贫血影响着约三分之一的手术患者。贫血会增加输血风险,影响中短期功能预后,增加合并症、并发症和费用。患者血液管理"(PBM)计划是对患者进行多学科综合管理,被视为优质护理的典范,其基本目标之一是纠正围手术期贫血。PBM 已被纳入手术患者的强化恢复计划:最近的《2021 年术后强化恢复路径》(西班牙语:RICA 2021)包括近 30 项有关 PBM 的间接建议。目标采用兰德/加州大学洛杉矶分校德尔菲法编制一份共识文件,以提高 RICA 2021 有关 PBM 建议在日常临床实践中的渗透率和优先级。材料和方法由来自血液学-血液治疗学、麻醉学和内科学的 6 位在贫血和 PBM 方面具有专长的专家组成一个协调小组。采用德尔菲兰德/加州大学洛杉矶分校的方法制定了一份调查问卷,以便就目前改善围手术期贫血管理的关键领域和优先专业行动达成共识。调查问题摘自 RICA 2021 路径中的 PBM 建议。参与者是应邀从 AWGE-GIEMSA 科学会议的发言人和 PBM 相关工作组的国家代表(塞维利亚文件、SEDAR HTF 部分和 RICA 2021 途径参与者)中选出的:在第一轮调查中,匿名在线问卷共有 28 个问题:其中 20 个是关于 ERAS 指南中的 PBM 概念(2 个是关于一般 PBM 组织,10 个是关于术前贫血的诊断和治疗,3 个是关于术后贫血的管理,5 个是关于输血标准),8 个是关于有待研究的方面。回答采用 10 分制(0 分:非常不同意,10 分:非常同意)。参与者还可以提出他们认为合适的其他意见。除了一个问题(问题 14)外,所有问题的平均得分都超过了 9 分,因此这些问题被认为是一致同意的。第二轮调查包括 37 个问题,是对第一轮调查的问题进行重新编排并吸收了参与者的意见后产生的。第二轮调查包括 37 个问题,这些问题是对第一轮调查问题的重新制定,并结合了参与者的意见。第二轮调查包括 2 个关于 PBM 计划一般组织的问题、15 个关于术前贫血诊断和治疗的问题、3 个关于术后贫血管理的问题、6 个关于输血标准的问题,以及 11 个关于有待未来调查的方面的问题。统计处理:表列出每个调查问题的平均值、中位数和 25-75 分位间值(表 1、表 2 和表 3)。除 3 项建议外,其他建议均在 8 分以上,且大部分建议的平均分在 9 分或以上。这些建议分为:1. "对所有有潜在出血风险的外科手术患者(包括孕妇)进行术前贫血检测和病因诊断是非常重要和必要的"。- 2. "术前治疗贫血应充分提前,并提供所有必要的血液捐助,以纠正这种状况"。3. "对于中度贫血 Hb 8-10 g/dL 且病情稳定的患者,术前输注任何单位的包装红细胞都是毫无道理的,因为这些患者可能要进行出血手术,而且手术不能延迟"。4. "建议普及外科和产科患者输注红细胞的限制性标准"。5. "应治疗术后贫血,以改善术后效果,加快术后短期和中期恢复"。我们的工作有助于确定适合在每家医院和所有患者中实施 PBM 计划的举措和绩效。
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引用次数: 0
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Revista Espanola de Anestesiologia y Reanimacion
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