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Association between calcium administration and outcomes during adult cardiopulmonary resuscitation at the emergency department 急诊成人心肺复苏过程中钙的使用与结果的关系
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-04-11 DOI: 10.4103/2452-2473.342805
Wachira Wongtanasarasin, Nat Ungrungseesopon, Nutthida Namsongwong, Pongsatorn Chotipongkul, Onwara Visavakul, Napatsakorn Banping, Worapot Kampeera, Phichayut Phinyo
OBJECTIVES: Calcium administration during cardiac arrest is limited in some circumstances, mainly due to lack of consistent evidence. This study aims to investigate whether calcium therapy administered during cardiac arrest at the Emergency Department is associated with good outcomes, including the probability of return of spontaneous circulation (ROSC), survival to hospital admission, survival to hospital discharge, and favorable neurological outcome at discharge. METHODS: We retrospectively reviewed 599 consecutive adult cardiac arrest events between 2016 and 2018. The primary outcome was the ROSC rate. Secondary outcomes included survival to hospital admission, survival to hospital discharge, and favorable neurologic outcome at hospital discharge. Multivariable logistic regression with inverse probability of treatment weighting was analyzed to examine the association between calcium administration and outcomes. RESULTS: Of 599 events, calcium was administered in 72 (12%) cases. The use of calcium during cardiopulmonary resuscitation (CPR) after adjusting for confounding factors was not associated with any better outcomes, including ROSC (adjusted odds ratio (aOR) 0.53, 95% confidence interval [CI] 0.24–1.17), survival to hospital admission (aOR 1.07, 95% CI 0.47–2.41), survival to hospital discharge (aOR 1.93, 95% CI 0.43–8.56), and favorable neurological outcome (aOR 6.60, 95% CI 0.72–60.74). Besides, calcium use in traumatic cardiac arrest patients was associated with unfavorable outcomes, including ROSC (aOR 0.02, 95% CI 0.00–0.09) and survival to hospital admission (aOR 0.16, 95% CI 0.03–0.84). CONCLUSION: The use of calcium during an adult cardiac arrest was not associated with better outcomes. Although associations drawn from this study did not indicate the causality, given calcium during CPR was linked to poorer outcomes in traumatic cardiac arrest patients, including ROSC and survival to hospital admission.
目的:心脏骤停期间钙的给药在某些情况下是有限的,主要是由于缺乏一致的证据。本研究旨在探讨急诊科心脏骤停期间给予钙治疗是否与良好的预后相关,包括自发循环恢复(ROSC)的概率、入院生存、出院生存以及出院时良好的神经系统预后。方法:我们回顾性分析了2016年至2018年间599例连续的成人心脏骤停事件。主要结果是ROSC率。次要结局包括住院时的生存、出院时的生存和出院时良好的神经预后。采用多变量logistic回归分析治疗权重的逆概率,以检验钙给药与预后之间的关系。结果:在599例事件中,72例(12%)给予钙。校正混杂因素后,心肺复苏(CPR)期间钙的使用与任何较好的结果无关,包括ROSC(校正优势比(aOR) 0.53, 95%可信区间[CI] 0.24-1.17)、生存至住院(aOR 1.07, 95% CI 0.47-2.41)、生存至出院(aOR 1.93, 95% CI 0.43-8.56)和良好的神经预后(aOR 6.60, 95% CI 0.72-60.74)。此外,外伤性心脏骤停患者的钙使用与不良结局相关,包括ROSC (aOR为0.02,95% CI为0.00-0.09)和住院前的生存(aOR为0.16,95% CI为0.03-0.84)。结论:在成人心脏骤停期间使用钙与更好的预后无关。虽然从本研究中得出的关联并没有表明因果关系,但在心肺复苏术中给予钙与创伤性心脏骤停患者较差的预后有关,包括ROSC和住院存活率。
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引用次数: 4
Epidemiology of mass casualty incidents in a tertiary care trauma center in eastern India: A retrospective observational study 印度东部三级护理创伤中心大规模伤亡事件的流行病学:一项回顾性观察研究
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-04-11 DOI: 10.4103/2452-2473.342806
C. Mohanty, R. Radhakrishnan, Shine Stephen, Mantu Jain, Asha P. Shetty, Alwin Issac, I. Shaji, Sebastian Chakola
OBJECTIVES: Disasters and mass casualty incidents (MCIs) that cause substantial mortality and morbidity have been increasing worldwide. The emergency department (ED) services manage MCIs by optimizing triage and providing health care with required resources. The present study attempted to describe the epidemiological characteristics and outcomes of MCIs presenting to the ED. METHODS: The present retrospective observational study was conducted at the ED of a tertiary care hospital on patients of MCI for 4 years from 2017 to 2021. The data were extracted from the ED disaster records and other paper-based patient records. Information on patient demography, date and time of arrival, mode of transport, method of arrival (direct or referral), type and mechanism of MCI, ED management, and outcome were recorded. Statistical analysis was performed using R, version 4.1.0. RESULTS: Analysis of 21 MCIs was conducted. Road traffic accidents (RTAs) were the predominant cause of MCIs. The majority of MCI victims, except for those of blast injuries, were men. The victims in medical emergencies were significantly younger than those in other MCI groups (P < 0.001). The majority of patients were brought to ED through ambulance services (n = 120 [47.1%]), followed by private vehicles (n = 112 [44.2%]). Most of the MCI victims (n = 143 [56.2%]) were brought to the ED during evening hours (4 pm–8 pm). The majority of victims belonged to the “Red” triage category (n = 110 [43.3%]). The injury severity score was significantly higher (P = 0.014) in the disaster group than in other trauma MCI groups (20 vs. 17). Autorickshaw occupants were the most common victims of mass casualty RTAs (n = 38 [40%]). Suturing (n = 97 [50%]) and dressing (n = 167 [88%]) were the most common ED procedures required by the victims of trauma MCIs. Of the total, 167 (66%) patients were discharged from the ED, 47 (19%) patients were admitted to wards, 13 (5%) patients were admitted to intensive care units, and 24 (9%) patients got referred to other centers. In addition, two patients died in the ED during treatment, whereas one patient was brought dead. CONCLUSIONS: RTAs dominate the MCIs and are affecting the young producative male population. The present study exhibited the severity of the cases in MCIs and their impact in the health-care setting, therefore signifying the importance of standardized MCI management protocols.
目标:在世界范围内,造成大量死亡率和发病率的灾害和大规模伤亡事件(MCIs)一直在增加。急诊科(ED)服务通过优化分类和提供医疗保健所需的资源来管理mci。本研究试图描述MCI在急诊科的流行病学特征和结局。方法:本回顾性观察性研究是在一家三级医院的急诊科对2017年至2021年4年的MCI患者进行的。数据是从急诊科灾难记录和其他纸质病人记录中提取的。记录患者人口统计、到达日期和时间、交通方式、到达方式(直接或转诊)、MCI类型和机制、ED管理和结果等信息。统计分析使用R 4.1.0版本。结果:对21例MCIs进行了分析。道路交通事故(rta)是MCIs的主要原因。除爆炸伤外,MCI的大多数受害者都是男性。急诊患者年龄明显低于其他MCI组(P < 0.001)。大多数患者通过救护车(n = 120[47.1%])被送往急诊科,其次是私家车(n = 112[44.2%])。大多数MCI患者(143例[56.2%])是在晚上(下午4点至8点)被送到急诊科的。大多数受害者属于“红色”分类(n = 110[43.3%])。灾难组损伤严重程度评分显著高于其他创伤MCI组(20比17)(P = 0.014)。机动三轮车乘客是大规模伤亡rta最常见的受害者(n = 38[40%])。缝合(n = 97[50%])和包扎(n = 167[88%])是创伤性MCIs受害者最常见的ED程序。其中,167例(66%)患者从急诊科出院,47例(19%)患者入住病房,13例(5%)患者入住重症监护病房,24例(9%)患者转诊至其他中心。此外,两名患者在治疗期间在急诊科死亡,而一名患者死亡。结论:rta在MCIs中占主导地位,并影响着年轻的育龄男性人群。本研究显示了MCI病例的严重程度及其对卫生保健环境的影响,因此表明了标准化MCI管理协议的重要性。
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引用次数: 1
Messenger ribonucleic acid vaccine-associated immune thrombocytopenia: A rare complication of vaccine. 信使核糖核酸疫苗相关的免疫性血小板减少:一种罕见的疫苗并发症。
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-04-01 DOI: 10.4103/2452-2473.342810
Mehmet Sami Islamoglu, Mehmet Dokur, Betul Borku Uysal, Mehmet Gunduz

Coronavirus disease-2019 continues to have a serious impact in countries with the effect of new variant viruses emerging with mutations. While the effectiveness and protection of the vaccine have been determined all over the world, some vaccine-related side effects can be detected in the form of cases. In our case, the patient was admitted to the emergency department of our hospital with complaints of weakness and progressive rash on his legs. Diffuse petechiae purpura on the legs of the patient was observed and complete blood count revealed thrombocytopenia. Peripheral blood smear supported the blood count test results with thrombocytopenia, secondary causes of thrombocytopenia were excluded, and the patient was diagnosed with vaccine-induced immune thrombocytopenia.

2019冠状病毒病继续对各国产生严重影响,新变异病毒出现了突变。虽然疫苗的有效性和保护作用在世界各地都已得到确定,但可以以病例的形式发现一些与疫苗有关的副作用。在我们的病例中,患者因虚弱和腿部进行性皮疹而被送往我院急诊科。患者腿部可见弥漫性瘀点紫癜,全血细胞计数显示血小板减少。外周血涂片支持血小板减少的血细胞计数检查结果,排除血小板减少的继发原因,诊断为疫苗性免疫性血小板减少症。
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引用次数: 1
Accuracy of emergency physicians' interpretation of computed tomography for urgent-emergent diagnoses in nontraumatic cases. 急诊医师对非创伤性病例急诊诊断的计算机断层扫描解释的准确性。
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-04-01 DOI: 10.4103/2452-2473.342804
Omer Faruk Karakoyun, Nalan Kozaci, Mustafa Avci, Huseyin Uzunay

Objective: The aim of this study is to evaluate the accuracy levels of the emergency physicians (EPs) managing the patient in the interpretation of the urgent-emergent pathological findings in thoracic and abdominal computed tomography (CT) scans.

Methods: The EPs interpreted the CT scans of patients who visited the emergency department because of nontraumatic causes. Then, a radiology instructor made final assessments of these CT scans. Based on the interpretation of the radiology instructor, the false-positive rate, false-negative rate, sensitivity, specificity, positive predictive value, negative predictive value, and kappa coefficient (κ) of the EPs' interpretations of the CT scans were calculated.

Results: A total of 268 thoracics and 185 abdominal CT scans were assessed in our study. The overall sensitivity and specificity of the EPs' interpretation of the thoracic CT scans were 90% and 89%, respectively, whereas the abdominal CT interpretation was 88% and 86%, respectively. There was excellent concordance between the EPs and the radiology instructor with regard to the diagnoses of pneumothorax, pulmonary embolism, pleural effusion, parenchymal pathology, and masses (κ: 0.90, κ: 0.87, κ: 0.71, κ: 0.79, and κ: 0.91, respectively) and to the diagnoses of intraabdominal free fluid, intraabdominal free gas, aortic pathology, splenic pathology, gallbladder pathology, mesenteric artery embolism, appendicitis, gynecological pathology, and renal pathology (κ: 1, κ: 0.92, κ: 0.96, κ: 0.88, κ: 0.80, κ: 0.79, κ: 0.89, κ: 0.88, and κ: 0.82, respectively).

Conclusion: The EPs are successful in the interpretation of the urgent-emergent pathological findings in thoracic and abdominal CT scans.

目的:本研究的目的是评估急诊医生(EPs)在解释胸部和腹部计算机断层扫描(CT)的紧急病理发现时的准确性水平。方法:EPs对因非创伤性原因就诊的急诊患者的CT扫描进行解释。然后,放射学讲师对这些CT扫描结果进行最终评估。根据放射学讲师的解释,计算EPs对CT扫描解释的假阳性率、假阴性率、敏感性、特异性、阳性预测值、阴性预测值和kappa系数(κ)。结果:在我们的研究中,共评估了268个胸部和185个腹部CT扫描。EPs对胸部CT扫描的总体敏感性和特异性分别为90%和89%,而腹部CT的总体敏感性和特异性分别为88%和86%。在气胸、肺栓塞、胸膜积液、实质病理、肿块的诊断上,EPs与指导医师的诊断具有良好的一致性(κ: 0.90, κ: 0.87, κ: 0.71, κ: 0.79, κ: 0.91),在腹内游离液、腹内游离气、主动脉病理、脾病理、胆囊病理、肠系膜动脉栓塞、阑尾炎、妇科病理、肾脏病理诊断上,EPs与指导医师的诊断具有良好的一致性(κ: 1, κ: 1)。κ0.92,κ:0.96:0.88,κ:0.80,κ:0.79,κ:0.89,κ:0.88,和κ:分别为0.82)。结论:EPs在解释胸部和腹部CT扫描中的紧急病理表现方面是成功的。
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引用次数: 1
Scrub typhus manifesting as electrocardiographic disturbance: A case report and review of literature 以心电图紊乱为表现的恙虫病1例报告及文献复习
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/2452-2473.336103
Samiksha Gupta, Gautam Jesrani, S. Gaba, Monica Gupta
Scrub typhus (ST) has wide organ system involvement, but cardiac involvement is paramount in this spectrum due to early hemodynamic compromise. Various forms of cardiac involvement have been described in the literature, but we are describing rare electrocardiographic changes in the ST infection. A young male presented in our emergency department with complaints of restlessness and vomiting of 2 days' duration. The patient was having stable vitals on presentation, but his electrocardiogram (ECG) demonstrated second-degree atrioventricular block type 1 (also known Mobitz 1) and Osborn wave in the precordial leads. Further, he was having thrombocytopenia and eventually diagnosed with ST. For this, appropriate antibiotic treatment was given, which led to considerable symptomatic improvement and reversal of the ECG changes.
恙虫病(ST)有广泛的器官系统受累,但由于早期血流动力学损害,心脏受累是最重要的。文献中描述了各种形式的心脏受累,但我们描述的是ST感染中罕见的心电图变化。一名年轻男性以躁动和呕吐2天的主诉来到我们的急诊科。患者入院时生命体征稳定,但心电图显示二度房室传导阻滞1型(也称为Mobitz 1型)和心前导联Osborn波。此外,他患有血小板减少症,最终被诊断为st。为此,给予适当的抗生素治疗,导致症状明显改善,心电图变化逆转。
{"title":"Scrub typhus manifesting as electrocardiographic disturbance: A case report and review of literature","authors":"Samiksha Gupta, Gautam Jesrani, S. Gaba, Monica Gupta","doi":"10.4103/2452-2473.336103","DOIUrl":"https://doi.org/10.4103/2452-2473.336103","url":null,"abstract":"Scrub typhus (ST) has wide organ system involvement, but cardiac involvement is paramount in this spectrum due to early hemodynamic compromise. Various forms of cardiac involvement have been described in the literature, but we are describing rare electrocardiographic changes in the ST infection. A young male presented in our emergency department with complaints of restlessness and vomiting of 2 days' duration. The patient was having stable vitals on presentation, but his electrocardiogram (ECG) demonstrated second-degree atrioventricular block type 1 (also known Mobitz 1) and Osborn wave in the precordial leads. Further, he was having thrombocytopenia and eventually diagnosed with ST. For this, appropriate antibiotic treatment was given, which led to considerable symptomatic improvement and reversal of the ECG changes.","PeriodicalId":46536,"journal":{"name":"Turkish Journal of Emergency Medicine","volume":"218 7 1","pages":"47 - 50"},"PeriodicalIF":0.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90750432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Catheter-directed thrombolysis in a COVID-19 patient complicated with pulmonary embolism 导管溶栓治疗新冠肺炎合并肺栓塞1例
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/2452-2473.336102
B. Kocas, K. Kılıçkesmez
Since December 2019, the novel coronavirus (COVID-19) outbreak has become an important public health problem and one of the most common causes of morbidity and mortality worldwide. COVID-19 is highly associated with thromboembolic events, like deep venous thrombosis and pulmonary embolism (PE). Catheter-directed thrombolysis (CDT) provides effective reperfusion for the treatment of PE. We report a patient who was presented with intermediate-risk PE and had a saccular aneurysm of the anterior cerebral artery. The patient was suffered from recent COVID-19 infection and ischemic stroke. As the patient had high bleeding risk for full-dose systemic thrombolytic therapy, CDT was the preferred method for reperfusion. Finally, the patient was discharged from the hospital uneventfully 4 days later. In the setting of high bleeding risk, CDT seems to be an effective and safe approach in patients with intermediate-risk PE.
自2019年12月以来,新型冠状病毒(COVID-19)疫情已成为一个重要的公共卫生问题,也是全球最常见的发病和死亡原因之一。COVID-19与深静脉血栓形成和肺栓塞(PE)等血栓栓塞事件高度相关。导管定向溶栓(CDT)为PE的治疗提供了有效的再灌注。我们报告一个病人谁提出了中等风险PE和脑前动脉囊状动脉瘤。患者近期感染新冠病毒并缺血性中风。由于全剂量全身溶栓治疗患者出血风险高,CDT是再灌注的首选方法。4天后,患者顺利出院。在高出血风险的情况下,CDT似乎是一种有效和安全的方法,用于中度风险PE患者。
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引用次数: 1
Resuscitation of hemorrhagic shock using normal saline does not damage the glycocalyx in the immediate resuscitation phase 失血性休克复苏使用生理盐水不损害糖萼在立即复苏阶段
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/2452-2473.336100
A. Pudjiadi, A. Firmansyah, D. M. Gunanti Soeyono, S. Bardosono, S. A. Jusman, Minarma Siagian, M. Lubis
OBJECTIVES: The objectives were to study the effect of aggressive resuscitation using normal saline on hemodynamics, serum atrial natriuretic peptide (ANP), syndecan-1 (marker of endothelial glycocalyx shedding), and extravascular lung water index (ELWI) following hemorrhagic shock. METHODS: Eleven male piglets (Sus scrofa) underwent blood drawing to create 20% drop in mean arterial pressure (MAP). Two-phase resuscitation was performed: Phase 1 using normal saline of an equal volume of blood drawn to create shock and Phase 2 using 40 ml/kg BW of normal saline to simulate hypervolemia and hemodilution. Heart rate, MAP, cardiac index (CI), systemic vascular resistance index, oxygen delivery (DO2), global end-diastolic volume index, ELWI, hemoglobin (Hb), lactate, ANP, and syndecan-1 at each phase and up to 60 min following Phase 2 resuscitation were recorded. RESULTS: Phase 2 resuscitation significantly decreased Hb concentration (P = 0.006), however, DO2 was maintained (P = 1.000). CI increased from shock to Phase 1 (P = 0.029) and further increase in Phase 2 resuscitation (P = 0.001). Overall, there was a transient increase of ANP following Phase 1 resuscitation, from 85.20 ± 40.86 ng/L at baseline to 106.42 ± 33.71 ng/L (P = 0.260). Serum syndecan-1 and ELWI change at all phases were not significant. CONCLUSIONS: We demonstrate compensatory protective mechanism despite overzealous fluid resuscitation. Compensatory increased CI despite decreased Hb maintained DO2. In the absence of inflammation, serum ANP did not increase significantly, no glycocalyx shedding occurred, subsequently no change in ELWI. We show that factors other than volume overload are more dominant in causing glycocalyx shedding.
目的:研究生理盐水积极复苏对失血性休克后血流动力学、血清房利钠肽(ANP)、syndecan-1(内皮糖基脱落标志物)和血管外肺水指数(ELWI)的影响。方法:对11头公仔猪(Sus scrofa)进行抽血,使平均动脉压(MAP)下降20%。进行两阶段复苏:第一阶段使用等量抽取的生理盐水造成休克,第二阶段使用40 ml/kg体重的生理盐水模拟高血容量和血液稀释。记录各阶段及二期复苏后60分钟内的心率、MAP、心脏指数(CI)、全身血管阻力指数、氧输送(DO2)、整体舒张末期容积指数、ELWI、血红蛋白(Hb)、乳酸、ANP和syndecan-1。结果:2期复苏显著降低Hb浓度(P = 0.006),但维持DO2 (P = 1.000)。从休克到第一阶段CI增加(P = 0.029),在第二阶段复苏时CI进一步增加(P = 0.001)。总体而言,第一阶段复苏后ANP短暂增加,从基线时的85.20±40.86 ng/L增加到106.42±33.71 ng/L (P = 0.260)。各期血清syndecan-1及ELWI变化均无统计学意义。结论:我们证明了过度液体复苏的代偿保护机制。尽管Hb降低,补偿性CI增加维持了DO2。在无炎症的情况下,血清ANP无明显升高,糖萼无脱落,ELWI无变化。我们发现,在引起糖萼脱落中,体积过载以外的因素更占主导地位。
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引用次数: 0
Clinical outcomes of in-hospital cardiac arrest in a tertiary hospital and factors related to 28-day survival: A retrospective cohort study 某三级医院院内心脏骤停的临床结局与28天生存率相关因素:一项回顾性队列研究
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/2452-2473.336101
M. Yakar, N. Yakar, Müslüm Akkılıç, Rasim Onur Karaoğlu, Tarkan Mıngır, N. Turgut
OBJECTIVES: The primary aim was to define factors related to the return of spontaneous circulation (ROSC) after in-hospital cardiac arrest (IHCA), and the secondary aim was to determine factors related to 28-day mortality in patients admitted to intensive care unit (ICU) after ROSC. METHODS: In this retrospective study, we included the patients who suffered from IHCA in a tertiary hospital between July 2016 and April 2019. Pre- and post-resuscitation characteristics of the patients and event characteristics were defined to reveal the independent factors associated with ROSC and 28-day survival. RESULTS: A total of 254 patients (median age 73 years, 58.3% males) underwent cardiopulmonary resuscitation (CPR). The ROSC rate was 45.7%. Of all, 51 patients (median age, 63 years, 54.9% males) were admitted to in-hospital ICUs. The 28-day survival rate was 31.4%. The independent risk factors were chronic kidney disease (odds ratio [OR], 3.18, 95% confidence interval [CI], 1.37–7.19, P = 0.007), chronic obstructive pulmonary disease (OR, 2.84, 95% CI, 1.23–6.61, P = 0.015), asystole as an initial rhythm (OR, 2.94, 95% CI, 1.27–6.79, P = 0.012), multi-trauma-related complications (OR, 21.11, 95% CI, 4.71–94.69, P < 0.001), and septic shock (OR, 4.10; 95% CI, 1.16–14.54, P = 0.029) for ROSC; and a cerebral performance category score >2 (OR, 20.86, 95% CI, 2.74–158.65, P = 0.003), Acute Physiology and Chronic Health Evaluation II score >14 (OR, 7.58, 95% CI, 1.06–54.23, P = 0.044) for 28-day mortality. CONCLUSIONS: Independent risk factors related to ROSC and 28-day mortality were defined in the study. However, further studies are needed to devise new strategies for increased hospital discharge with preserved neurologic functions.
目的:主要目的是确定院内心脏骤停(IHCA)后自发循环恢复(ROSC)的相关因素,次要目的是确定ROSC后入住重症监护病房(ICU)患者28天死亡率的相关因素。方法:在这项回顾性研究中,我们纳入了2016年7月至2019年4月在某三级医院患有IHCA的患者。定义患者复苏前后特征和事件特征,以揭示与ROSC和28天生存率相关的独立因素。结果:共有254例患者(中位年龄73岁,58.3%男性)接受了心肺复苏(CPR)。ROSC率为45.7%。51例患者(中位年龄63岁,男性54.9%)入住院内icu。28天生存率为31.4%。独立危险因素为慢性肾脏疾病(优势比[OR], 3.18, 95%可信区间[CI], 1.37-7.19, P = 0.007)、慢性阻塞性肺疾病(OR, 2.84, 95% CI, 1.23-6.61, P = 0.015)、作为初始节律的心脏骤停(OR, 2.94, 95% CI, 1.27-6.79, P = 0.012)、多创伤相关并发症(OR, 21.11, 95% CI, 4.71-94.69, P < 0.001)和感染性休克(OR, 4.10;ROSC的95% CI, 1.16-14.54, P = 0.029);28天死亡率脑功能分类评分>2 (OR, 20.86, 95% CI, 2.74-158.65, P = 0.003),急性生理和慢性健康评估II评分>14 (OR, 7.58, 95% CI, 1.06-54.23, P = 0.044)。结论:研究确定了与ROSC和28天死亡率相关的独立危险因素。然而,需要进一步的研究来设计新的策略来增加保留神经功能的出院率。
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引用次数: 1
Extracorporeal membrane oxygenation experiences during COVID-19 pandemic, third wave with younger patients: A retrospective observational study 第三波COVID-19大流行期间年轻患者的体外膜氧合经验:一项回顾性观察研究
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/2452-2473.336106
A. Küçük, M. Küçük, O. Ayçiçek, G. Altun, A. Özdemir
OBJECTIVES: In this article, the results of severe coronavirus disease 2019 (COVID-19) cases followed with extracorporeal membrane oxygenation (ECMO) support in a 3-month period in the third wave when there were an increased number of cases of young patients in our intensive care unit (ICU) were presented. METHODS: The study was carried out with all COVID-19 patients who were given ECMO support in our tertiary referral hospital ICU after obtaining the consent of the Ministry of Health Scientific Research Platform and after the approval of the local ethics committee. Patient data were obtained retrospectively from intensive care bedside follow-up charts and computer records. The demographic and clinical characteristics of the patients were presented in average, median, and percentages. The data of the patients were evaluated and compared with the current literature. RESULTS: ECMO treatment was applied in seven patients who were followed up with severe COVID-19 pneumonia in the last 3 months. Venovenous extracorporeal membrane oxygenation (VV-ECMO) was applied to all patients. Five (71.5%) of seven patients were weaned from ECMO. Four (57.2%) of seven patients were discharged from the ICU and hospital in good health. While two of the patients had a cesarean section (C/S) before ECMO, one patient underwent C/S under ECMO. All three newborns were delivered via C/S and all were premature (C/S dates were 35 weeks, 32 weeks, and 27 weeks), and all were discharged from the hospital in good health. CONCLUSION: Our experience shows that ECMO in COVID-19 patients is a lifesaving treatment option that can be successfully applied in severe acute respiratory distress syndrome cases who do not respond to conventional treatments.
目的:本文介绍了重症监护病房(ICU)年轻患者数量增加的第三波重症肺炎(COVID-19)病例后3个月内体外膜氧合(ECMO)支持的结果。方法:经卫生部科研平台同意并经当地伦理委员会批准,在我院三级转诊医院ICU接受ECMO支持的所有COVID-19患者进行研究。患者资料回顾性地从重症监护床边随访图表和计算机记录中获得。患者的人口学和临床特征以平均值、中位数和百分比表示。对患者资料进行评估,并与现有文献进行比较。结果:最近3个月随访的7例重症COVID-19肺炎患者均采用ECMO治疗。所有患者均行静脉-静脉体外膜氧合(VV-ECMO)。7例患者中有5例(71.5%)脱离ECMO。7例患者中4例(57.2%)健康出院。其中2例患者在ECMO前进行了剖宫产(C/S), 1例患者在ECMO下进行了C/S。所有三名新生儿均通过C/S分娩,均为早产儿(C/S日期分别为35周、32周和27周),均健康出院。结论:我们的经验表明,ECMO在COVID-19患者中是一种挽救生命的治疗选择,可以成功应用于常规治疗无效的严重急性呼吸窘迫综合征病例。
{"title":"Extracorporeal membrane oxygenation experiences during COVID-19 pandemic, third wave with younger patients: A retrospective observational study","authors":"A. Küçük, M. Küçük, O. Ayçiçek, G. Altun, A. Özdemir","doi":"10.4103/2452-2473.336106","DOIUrl":"https://doi.org/10.4103/2452-2473.336106","url":null,"abstract":"OBJECTIVES: In this article, the results of severe coronavirus disease 2019 (COVID-19) cases followed with extracorporeal membrane oxygenation (ECMO) support in a 3-month period in the third wave when there were an increased number of cases of young patients in our intensive care unit (ICU) were presented. METHODS: The study was carried out with all COVID-19 patients who were given ECMO support in our tertiary referral hospital ICU after obtaining the consent of the Ministry of Health Scientific Research Platform and after the approval of the local ethics committee. Patient data were obtained retrospectively from intensive care bedside follow-up charts and computer records. The demographic and clinical characteristics of the patients were presented in average, median, and percentages. The data of the patients were evaluated and compared with the current literature. RESULTS: ECMO treatment was applied in seven patients who were followed up with severe COVID-19 pneumonia in the last 3 months. Venovenous extracorporeal membrane oxygenation (VV-ECMO) was applied to all patients. Five (71.5%) of seven patients were weaned from ECMO. Four (57.2%) of seven patients were discharged from the ICU and hospital in good health. While two of the patients had a cesarean section (C/S) before ECMO, one patient underwent C/S under ECMO. All three newborns were delivered via C/S and all were premature (C/S dates were 35 weeks, 32 weeks, and 27 weeks), and all were discharged from the hospital in good health. CONCLUSION: Our experience shows that ECMO in COVID-19 patients is a lifesaving treatment option that can be successfully applied in severe acute respiratory distress syndrome cases who do not respond to conventional treatments.","PeriodicalId":46536,"journal":{"name":"Turkish Journal of Emergency Medicine","volume":"9 1","pages":"36 - 43"},"PeriodicalIF":0.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76355183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Abdominal twitches due to ICD lead dislodgement; A case report ICD导联脱位引起的腹部抽搐;病例报告
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-01-01 DOI: 10.4103/2452-2473.336099
Yusuf Oktay, Muhammed Rıdvan Ersoysal, Burcin Akgun, G. Kuş, E. Arslan
Malfunctions of implantable cardiac devices have the potential to be catastrophic. A 63-year-old patient was admitted to our emergency department with new-onset abdominal pain and sensation of twitching on his abdominal wall. One month ago, an implantable cardioverter-defibrillator (ICD) was implanted in him to prevent malignant ventricular arrhythmias. An electrocardiogram was obtained that showed pace spikes unrelated to QRS complexes. The patient was diagnosed with ICD lead dislodgement and the lead was repositioned in another procedure. In conclusion, emergency physicians should be familiar with the problems of implantable cardiac devices.
植入式心脏装置的故障可能是灾难性的。一位63岁的病人因新发腹痛和腹壁抽搐而被急诊科收治。一个月前,一个植入式心脏转复除颤器(ICD)被植入他体内,以防止恶性室性心律失常。获得的心电图显示与QRS复合物无关的心率峰值。患者被诊断为ICD导联脱位,并在另一次手术中重新定位导联。总之,急诊医生应该熟悉植入式心脏装置的问题。
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Turkish Journal of Emergency Medicine
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