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Comparison of pain and extent of anesthesia in digital blocks for isolated finger lacerations: A randomized controlled trial. 孤立手指裂伤手指阻滞疼痛和麻醉程度的比较:一项随机对照试验。
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-07-01 DOI: 10.4103/tjem.tjem_344_21
Ali Jarragh, Ali Lari, Waleed Burhamah, Mohammed Alherz, Abdullah Nouri, Yahia Alshammari, Ameer Al-Jasim, Sulaiman AlRefai, Naser Alnusif

Objectives: Digital injuries are among the most common presentations to the emergency department. In order to sufficiently examine and manage these injuries, adequate, prompt, and predictable anesthesia is essential. In this trial, we aim to primarily compare the degree of pain and anesthesia onset time between the two-injection dorsal block technique (TD) and the single-injection volar subcutaneous block (SV) technique. Further, we describe the temporal and anatomical effects of both techniques for an accurate delineation of the anesthetized regions.

Methods: This is a single-center prospective randomized controlled trial involving patients presenting with isolated wounds to the fingers requiring primary repair under local anesthesia. Patients were randomized to either the SV or TD blocks. The primary outcome was procedure-related pain (Numerical Rating Scale). Further, we assessed the extent of anesthesia along with the anesthesia onset time.

Results: A total of 100 patients were included in the final analysis, 50 on each arm of the study. The median pain score during injection was significantly higher in patients who received TD block than patients who received SV block (median [interquartile range] = 4 [2.25, 5.00] vs. 3.00 [2.00, 4.00], respectively, P = 0.006). However, anesthesia onset time was not statistically different among the groups (P = 0.39). The extent of anesthesia was more predictable in the dorsal block compared to the volar block.

Conclusion: The single-injection volar subcutaneous blocks are less painful with a similar anesthesia onset time. Injuries presenting in the proximal dorsal region may benefit from the two-injection dorsal blocks, given the anatomical differences and timely anesthesia of the region.

目的:数字损伤是急诊室最常见的表现之一。为了充分检查和处理这些损伤,充分、及时和可预测的麻醉是必不可少的。在本试验中,我们的主要目的是比较两次注射背侧阻滞技术(TD)和单次注射掌侧皮下阻滞技术(SV)的疼痛程度和麻醉开始时间。此外,我们描述了这两种技术的时间和解剖效果,以准确描绘麻醉区域。方法:这是一项单中心前瞻性随机对照试验,涉及在局部麻醉下需要初级修复的孤立手指伤口患者。患者被随机分为SV组和TD组。主要结果是手术相关疼痛(数值评定量表)。此外,我们评估了麻醉程度和麻醉开始时间。结果:最终分析共纳入100例患者,每组各50例。注射过程中,接受TD阻断的患者疼痛评分中位数明显高于接受SV阻断的患者(中位数[四分位数间距]= 4 [2.25,5.00]vs. 3.00 [2.00, 4.00], P = 0.006)。麻醉起效时间各组间差异无统计学意义(P = 0.39)。与掌侧阻滞相比,背侧阻滞的麻醉程度更可预测。结论:单次注射掌侧皮下阻滞在麻醉起效时间相近的情况下疼痛较小。鉴于解剖差异和该区域的及时麻醉,在近背区域出现的损伤可能受益于两次注射背侧阻滞。
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引用次数: 1
Characteristics of pediatric COVID-19 patients admitted to the emergency department and factors associated with pneumonia. 急诊科收治小儿COVID-19患者的特点及肺炎相关因素
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-07-01 DOI: 10.4103/2452-2473.348434
Ali Yurtseven, Caner Turan, Gizem Güner Özenen, Halit Işik, Zümrüt Şahbudak Bal, Rüçhan Sertöz, Eylem Ulaş Saz

Objectives: Coronavirus disease 2019 (COVID-19) that causes a respiratory illness, continues to be a global pandemic. In this study, we purpose to identify the features of children with COVID-19 and the factors affecting disease severity.

Methods: This is a retrospective, observational study was conducted on patients who presented with suspicion of COVID-19 from April 1, 2020, to March 31, 2021, at a tertiary care medical center in Turkey. The characteristics of 640 children who were confirmed to have COVID-19 by real-time reverse transcription-polymerase chain reaction were retrieved from medical records.

Results: The mean age of the cases was 10 ± 6 years, and 56% of them were male. Seasonal difference did not affect the number of cases. The majority of the cases (n = 501, 78%) were infected by family members. Fever (67%) and cough (38%) were common complaints. The mean duration of fever was 1.9 ± 1.1 days. One-fourth of the cases were asymptomatic, 462 (72%) had mild upper respiratory tract infections, and 18 (3%) had pneumonia. Patients with pneumonia were more likely to have comorbidities and had a longer fever duration (both P < 0.001). Fever, cough, and respiratory distress were more common in patients with pneumonia (P = 0.010, P = 0.023, and P < 0.001, respectively). The mean C-reactive protein (CRP) value of the patients with pneumonia was significantly higher than that of the others (P < 0.001). A total of 70 (11%) complicated patients were hospitalized, 5 of them requiring intensive care admission. All hospitalized patients were discharged with recovery.

Conclusions: Although pediatric COVID-19 patients tended to have a mild disease, some children with comorbidities can still develop a severe illness. CRP value is a useful indicator in the diagnosis of COVID-19 pneumonia. Furthermore, the prevalence rate of COVID-19 did not decrease with hot seasons.

2019冠状病毒病(COVID-19)是一种引起呼吸道疾病的疾病,目前仍在全球流行。在本研究中,我们旨在确定COVID-19儿童的特征以及影响疾病严重程度的因素。方法:本研究是一项回顾性观察性研究,对2020年4月1日至2021年3月31日在土耳其一家三级医疗中心疑似COVID-19的患者进行了研究。从病历中检索实时逆转录聚合酶链反应确诊的640例儿童的特征。结果:患者平均年龄为10±6岁,男性占56%。季节差异对病例数没有影响。大多数病例(n = 501, 78%)是由家庭成员感染的。发热(67%)和咳嗽(38%)是常见的主诉。平均发热时间1.9±1.1 d。无症状者占1 / 4,轻度上呼吸道感染462例(72%),肺炎18例(3%)。肺炎患者有合并症的可能性更大,发热持续时间更长(P < 0.001)。发热、咳嗽和呼吸窘迫在肺炎患者中更为常见(P = 0.010, P = 0.023, P < 0.001)。肺炎患者的c反应蛋白(CRP)均值显著高于其他组(P < 0.001)。共有70例(11%)并发症患者住院,其中5例需要重症监护。所有住院患者均康复出院。结论:虽然儿童COVID-19患者往往病情较轻,但一些有合并症的儿童仍可能发展为严重疾病。CRP值是诊断COVID-19肺炎的有用指标。此外,2019冠状病毒病的患病率不随炎热季节而下降。
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引用次数: 1
A rare complication of cardiopulmonary resuscitation applied during transportation by ambulance: A case report of flail chest. 救护车运送过程中心肺复苏的罕见并发症:连枷胸1例。
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-07-01 DOI: 10.4103/2452-2473.348437
Güner Yurtsever, Adnan Yamanoglu, Ejder Saylav Bora, Fatih Esad Topal

Cardiopulmonary resuscitation (CPR) to be applied during patient transfer by ambulance differs from CPR applied in the field or in the hospital in terms of physical condition. Especially the deeper and faster chest compressions recommended in the latest CPR guidelines, when administered during ambulance transport, may result in a further increase in traumatic CPR complications. However, in the current CPR guidelines, there are no clear recommendations regarding additional measures that can be taken to reduce the complications and increase the efficiency of CPR during patient transport. In this study, a case of flail chest that developed after short-term CPR application during ambulance transport is presented. The aim of this study was to evaluate the flail chest complication and solution suggestions that may occur due to chest compressions applied during transportation.

在救护车运送病人的过程中实施的心肺复苏术(CPR)与在现场或医院实施的心肺复苏术在身体状况方面有所不同。特别是最新CPR指南中建议的更深更快的胸外按压,在救护车运输过程中进行,可能会导致创伤性CPR并发症的进一步增加。然而,在目前的心肺复苏术指南中,没有明确的建议可以采取额外的措施来减少病人转运过程中的并发症和提高心肺复苏术的效率。在这项研究中,连枷胸的情况下,短期心肺复苏术后发展的救护车运输提出。本研究的目的是评估运输过程中胸部按压可能导致的连枷胸并发症及解决建议。
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引用次数: 0
Comparison of endotracheal intubation with Macintosh versus King Vision video laryngoscope using coronavirus disease 2019 barrier box on manikins: A randomized crossover study. 使用Macintosh和King Vision视频喉镜在人体模型上使用冠状病毒2019屏障盒进行气管插管的比较:一项随机交叉研究。
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-07-01 DOI: 10.4103/2452-2473.348436
Satyabrata Guru, Neha Singh, Sangeeta Sahoo, Upendra Hansda, Chittaranjan Mohanty

Background: Coronavirus disease 2019 (COVID-19) virus usually spreads through aerosol and close contact. Frontline health-care workers handle aerosol-generating procedures like endotracheal intubation. To reduce this risk, COVID-19 barrier box came into the picture. However, the COVID-19 barrier box may compromise easy and successful intubation, and their limitation must be studied.

Objectives: The objective of this study was to assess the time to successful intubation with or without the COVID-19 barrier box using the Macintosh laryngoscope and King Vision video laryngoscope (KVVL). We also assessed the first-pass success rate, ease of intubation, Cormack-Lehane (CL) grade, and requirement of external laryngeal manipulation.

Methods: We conducted this manikin-based randomized crossover study to assess the time to successful intubation by anesthesiologists (22) and emergency physicians (11) having 1 year or more experience with or without COVID-19 barrier box by using the Macintosh laryngoscope and KVVL. Our study randomized the sequence of the four different intubation scenarios.

Results: The comparison of mean duration of intubation between KVVL (13.21 ± 4.05 s) and Macintosh laryngoscope (12.89 ± 4.28 s) with COVID-19 barrier box was not statistically significant (95% confidence interval: 1.21-0.97). The ease of intubation, number of attempts, and requirement of external laryngeal manipulation were not statistically significant. Intubations were statistically significant more difficult with barrier box in view of higher CL grade.

Conclusion: Time to intubation was longer with COVID-19 barrier box using KVVL as compared to Macintosh laryngoscope which was statistically not significant.

背景:2019冠状病毒病(COVID-19)病毒通常通过气溶胶和密切接触传播。一线医护人员处理气管内插管等产生气溶胶的程序。为了降低这种风险,COVID-19屏障箱应运而生。然而,COVID-19屏障盒可能会影响插管的简单和成功,必须研究其局限性。目的:本研究的目的是评估使用Macintosh喉镜和King Vision视频喉镜(KVVL)成功插管或不使用COVID-19屏障盒的时间。我们还评估了一次通过成功率、插管难易程度、Cormack-Lehane (CL)分级和喉外操作的要求。方法:我们进行了一项基于人体模型的随机交叉研究,评估麻醉医师(22名)和急诊医师(11名)使用Macintosh喉镜和KVVL使用或不使用COVID-19屏障盒1年及以上经验的成功插管时间。我们的研究将四种不同插管方案的顺序随机化。结果:带COVID-19屏障盒的KVVL喉镜(13.21±4.05 s)与Macintosh喉镜(12.89±4.28 s)的平均插管时间比较,差异无统计学意义(95%可信区间:1.21 ~ 0.97)。插管难易程度、插管次数、喉外操作要求差异无统计学意义。考虑到更高的CL级别,使用屏障盒插管有统计学意义。结论:与Macintosh喉镜相比,KVVL使用COVID-19屏障盒插管时间更长,差异无统计学意义。
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引用次数: 1
Defective barcode sign – A newer sonographic sign in hydropneumothorax 条形码缺陷征象——气胸积液的一种较新的超声征象
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-04-11 DOI: 10.4103/2452-2473.342809
S. Mahalingam, G. Rajendran, A. Sadasivam, Manu Ayyan, V. Pillai
Effusive pneumothorax can be hemopneumothorax, pyopneumothorax, or hydropneumothorax depending on the type of fluid compartment within the pleural cavity. Hydropneumothorax is the abnormal collection of air and serous fluid within the pleural cavity. Here, we report a case of a 34-year-old male who presented to the emergency department with cough and breathlessness. We did bedside point-of-care ultrasound-assisted clinical evaluation as the patient was vitally unstable, which showed “hydro point” and “defective barcode sign,” which suggested hydropneumothorax. We present these clinical evaluation details, imaging/sonographic findings, and patient management in this case report.
根据胸膜腔内液体腔的类型,积液性气胸可分为血气胸、脓气胸或气胸积液。气胸是胸膜腔内空气和浆液的异常聚集。在这里,我们报告一个34岁的男性谁提出了咳嗽和呼吸困难的急诊科。由于患者生命不稳定,我们做了床边点超声辅助临床评估,显示“hydro point”和“defective barcode sign”,提示气胸积液。我们在本病例报告中介绍这些临床评估细节,影像学/超声检查结果和患者管理。
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引用次数: 1
Cardiac tamponade due to right atrial rupture 右心房破裂引起的心包填塞
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-04-11 DOI: 10.4103/2452-2473.342803
G. Rajendran, G. Babu, Vinodha Chandrasekar, Rajeshwari Kagne, B. Nathan
Cardiac tamponade is a cardiac emergency that requires urgent intervention. Cardiac tamponade due to penetrating cardiac injury requires urgent thoracotomy. As per the guidelines, pericardiocentesis can be done as a bridge to thoracotomy. However, no clear guidelines exist on the management of cardiac tamponade due to blunt cardiac injury. In the following case report, we propose a management plan for blunt cardiac injury in the emergency department. In the following case report, we describe a patient with a road traffic accident who had a blunt cardiac injury and had cardiac tamponade for whom we did not do emergency pericardiocentesis. Instead, we managed the patient with iv fluids and blood transfusion and the patient was taken up for immediate emergency thoracotomy. Not all cardiac tamponade requires pericardiocentesis. Cardiac tamponade due to injury to the low-pressure system can be best managed by initial resuscitation followed by emergency thoracotomy. We also propose a management plan for managing a patient with cardiac tamponade due to blunt cardiac injury when the injury can be visible in the low-pressure chambers.
心脏填塞是一种需要紧急干预的心脏急症。由于心脏穿透性损伤导致的心包填塞需要紧急开胸。根据指南,心包穿刺术可以作为开胸手术的桥梁。然而,对于钝性心脏损伤引起的心包填塞的处理尚无明确的指导方针。在以下的病例报告中,我们提出了在急诊科钝性心脏损伤的处理方案。在下面的病例报告中,我们描述了一位道路交通事故患者,他有钝性心脏损伤和心脏填塞,我们没有对他进行紧急心包穿刺术。相反,我们对病人进行了静脉输液和输血,并立即对病人进行了紧急开胸手术。并非所有的心包填塞都需要心包穿刺。由于低压系统损伤引起的心包填塞可以通过初始复苏和紧急开胸来最好地处理。我们还提出了一个管理计划,处理钝性心脏损伤引起的心包填塞,当损伤可以在低压室中看到时。
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引用次数: 0
Auricular avulsion injuries: Literature review and management algorithm 耳穴撕脱伤:文献回顾及处理方法
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-04-11 DOI: 10.4103/2452-2473.342811
Mohamed A. Al-Ali, F. Abu-Zidan
Traumatic ear avulsion (TEA) may have tremendous psychological consequences if not managed properly. There are no clear guidelines on the surgical management of these injuries, especially in developing countries where microsurgical facilities are lacking. We aimed to review the literature on surgical management of TEA with the main focus on direct re-attachment (DR) so as to develop a surgical management algorithm that can be applied in the absence of microsurgical facilities. We performed an extensive review of the relevant English literature on papers indexed in PubMed describing TEA repaired with DR without restriction to a specific publication time window. A total of 28 cases in 18 publications were reviewed and analyzed. Our results indicate that in the acute setting with no available microvascular expertise, DR of auricular avulsion injuries can be better than other nonmicrosurgical techniques in generating good esthetic results, especially in incomplete auricular avulsion and small segment avulsion. The operative approach depends on the clinical setting. DR of the auricular avulsion injuries is an accepted approach. It produces good cosmetic outcomes while preserving the auricular area for future reconstruction in case of re-attachment failure.
外伤性耳部撕脱术(TEA)如果处理不当,可能会造成严重的心理后果。对于这些损伤的外科治疗没有明确的指导方针,特别是在缺乏显微外科设备的发展中国家。我们旨在回顾有关TEA手术管理的文献,主要关注直接再附着(DR),以开发一种可以在缺乏显微外科设备的情况下应用的手术管理算法。我们对PubMed检索的相关英文文献进行了广泛的回顾,这些文献描述了用DR修复TEA,不受特定出版时间窗口的限制。本文对18篇文献中的28例病例进行了综述和分析。我们的研究结果表明,在没有微血管专业知识的急性情况下,耳廓撕脱伤的DR比其他非显微手术技术更能产生良好的美学效果,特别是在不完全性耳廓撕脱伤和小段撕脱伤中。手术入路取决于临床情况。耳部撕脱伤的DR是一种公认的方法。它产生了良好的美容效果,同时保留了耳廓区域,以便在再植失败的情况下将来重建。
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引用次数: 2
A case report on rectus sheath hematoma in an intubated COVID-19 patient 新型冠状病毒肺炎插管患者直肌鞘血肿1例报告
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-04-11 DOI: 10.4103/2452-2473.342807
Bhasyani Nagaretnam
Rectus sheath hematoma (RSH) is a life-threatening condition. Its pathology lies behind its unique anatomy. Critically ill COVID-19 patients are managed in the emergency department for longer periods while awaiting critical care admission. Therefore, more complex procedures such as prone positioning are performed in the emergency department to ensure patient care continues. We report this case of RSH in an intubated critically ill COVID-19 patient requiring prone position. During her stay in the Emergency Department Acute Care Unit, she developed anemia, uremia, and worsening hypoxia. Emergency contrast-enhanced computed tomography leads to our diagnosis of RSH. She was treated with a conservative approach and blood transfusion. We would like to highlight this case for its diagnostic complexity since this ventilated patient required both biochemical and radiological markers to diagnose RSH in combination with high suspicion levels. RSH must be considered in patients with risk factors such as prone position and anticoagulant usage. Last, a holistic approach to critically ill patients will not only benefit patients but also health-care profession. The direction of care should be decided based on the patient's condition, imaging, and hospital resources.
直肌鞘血肿(RSH)是一种危及生命的疾病。它独特的解剖结构背后隐藏着病理学。COVID-19危重患者在等待重症监护住院期间,在急诊科接受更长时间的管理。因此,更复杂的程序,如俯卧位在急诊科进行,以确保病人护理的继续。我们报告了一例需要俯卧位的插管危重COVID-19患者的RSH。在急诊科急症监护室住院期间,她出现贫血、尿毒症和缺氧恶化。紧急对比增强计算机断层扫描导致我们诊断为RSH。她接受了保守治疗和输血。我们想强调这个病例的诊断复杂性,因为这个通气的病人需要生化和放射学标记来诊断RSH,并结合高怀疑水平。有俯卧位和使用抗凝剂等危险因素的患者必须考虑RSH。最后,对危重患者采取全面的治疗方法,不仅有利于患者,也有利于医疗保健行业。护理方向应根据患者的病情、影像学和医院资源来决定。
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引用次数: 3
Manual versus mechanical chest compression in in-hospital cardiac arrest: A retrospective cohort in emergency department patients 手动与机械胸外按压在院内心脏骤停:回顾性队列急诊科患者
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-04-11 DOI: 10.4103/2452-2473.342808
A. Şener, G. P. Günaydın, F. Tanrıverdi, Ayhan Özhasenekler, Ş. Gökhan, Gülhan Kurtoğlu Çelik, Özcan Sağlam, Nihal Ertürk
OBJECTIVE: Mechanical chest compression (CC) devices are frequently used in in-hospital and out-of-hospital settings. In this study, mechanical and manual CC in in-hospital cardiac arrest was compared in terms of survival. METHODS: Adult patients who were admitted to the emergency department (ED) for 2 years period and had cardiac arrest in the ED were included in this retrospective, observational study. Return of spontaneous circulation (ROSC), 7-day and 30-day survival and hospital discharge data were compared between the two groups of patients who underwent manual CC and those who had mechanical CC with the Lund University Cardiac Assist System-2 device. RESULTS: Although the rate of ROSC in the mechanical CC group was lower than in the manual CC group, this difference was not statistically significant (41.7% vs. 50.4%; P = 0.133). The 7-day survival rate was found to be statistically significantly higher in the mechanical CC group (19.4% vs. 8.9%; P = 0.012). The 30-day survival rate was also found to be high in the mechanical CC group, but this difference was not statistically significant (10.6% vs. 7.3%; P = 0.339). CONCLUSION: In the light of these results, we can say that the use of piston-based mechanical CC devices in ED may be beneficial. More reliable results can be obtained with a prospective study to be performed in the ED.
目的:机械胸外按压(CC)装置在医院内外的应用非常广泛。在这项研究中,比较了院内心脏骤停患者的机械和手动CC的生存率。方法:回顾性观察性研究纳入了在急诊科(ED)住院2年并在ED发生心脏骤停的成年患者。比较两组患者的自发循环恢复(ROSC)、7天和30天的生存和出院数据,这两组患者分别采用隆德大学心脏辅助系统-2装置进行手动CC和机械CC。结果:虽然机械CC组ROSC发生率低于手动CC组,但差异无统计学意义(41.7% vs 50.4%;P = 0.133)。机械CC组7天生存率显著高于机械CC组(19.4% vs. 8.9%;P = 0.012)。机械CC组的30天生存率也较高,但差异无统计学意义(10.6% vs. 7.3%;P = 0.339)。结论:基于这些结果,我们可以说在ED中使用活塞式机械CC装置可能是有益的。在急诊科进行前瞻性研究可以获得更可靠的结果。
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引用次数: 0
The effect of calcium gluconate in the treatment of hyperkalemia 葡萄糖酸钙治疗高钾血症的效果
IF 0.9 Q3 EMERGENCY MEDICINE Pub Date : 2022-04-11 DOI: 10.4103/2452-2473.342812
N. G. Celebi Yamanoglu, Adnan Yamanoğlu
OBJECTIVES: Intravenous (IV) calcium salts are routinely recommended as a cardio-protective therapy in the emergency treatment of severe hyperkalemia. However, this recommendation is supported by a low level of evidence and is anecdotal. The aim of this study is to determine the effectiveness of IV Calcium (Ca) gluconate in the treatment of hyperkalemia. MATERIALS AND METHODS: Patients with hyperkalemia and with the electrocardiogram (ECG) changes due to hyperkalemia over a 1 year period were included in this prospective observational study. Patients’ ECGs were measured, before and after IV Ca-gluconate treatment and after normalization of potassium levels. Wilcoxon test and McNemar's test were used to compare the ECG parameters before and after Ca-gluconate therapy. RESULTS: The mean potassium value of 111 patients who met the inclusion criteria was 7.1 ± 0.6 mmol/l. In this study, a total of 243 ECG pathology related to hyperkalemia, 79 of which included main rhythm disorders, and the remaining 164 were nonrhythm disorders in ECG parameters, were analyzed. No statistically significant changes were determined in patients’ nonrhythm ECG disorders with IV Ca-gluconate treatment (P = 0.125). However, nine of the 79 main rhythm disorders due to hyperkalemia improved with calcium gluconate treatment and this change was statistically significant (P < 0.004). CONCLUSION: IV Ca-gluconate therapy was found to be effective, albeit to a limited degree, in main rhythm ECG disorders due to hyperkalemia, but it was not found to be effective in nonrhythm ECG disorders due to hyperkalemia. Therefore, Ca-gluconate may be effective only in the main rhythm disorders due to hyperkalemia.
目的:静脉(IV)钙盐被常规推荐作为严重高钾血症紧急治疗的心脏保护疗法。然而,这一建议的证据水平较低,而且是道听途说。本研究的目的是确定静脉注射葡萄糖酸钙治疗高钾血症的有效性。材料和方法:本前瞻性观察研究纳入了1年以上高钾血症患者和因高钾血症而出现心电图改变的患者。在静脉注射葡萄糖酸钙治疗前后和钾水平正常化后,测量患者的心电图。采用Wilcoxon试验和McNemar试验比较葡萄糖酸盐治疗前后的心电图参数。结果:符合纳入标准的111例患者平均钾值为7.1±0.6 mmol/l。本研究共分析243例与高钾血症相关的心电图病理,其中79例为主要节律障碍,其余164例为心电图参数非节律障碍。静脉注射葡萄糖酸钙治疗患者的非节律性心电图疾病无统计学意义变化(P = 0.125)。然而,79例高钾血症引起的主要节律障碍中有9例在葡萄糖酸钙治疗后得到改善,这一变化具有统计学意义(P < 0.004)。结论:葡萄糖酸钠静脉治疗对高钾血症引起的主要心律失常有一定的疗效,但对高钾血症引起的非心律失常无明显疗效。因此,葡萄糖酸钙可能仅对高钾血症引起的主要节律障碍有效。
{"title":"The effect of calcium gluconate in the treatment of hyperkalemia","authors":"N. G. Celebi Yamanoglu, Adnan Yamanoğlu","doi":"10.4103/2452-2473.342812","DOIUrl":"https://doi.org/10.4103/2452-2473.342812","url":null,"abstract":"OBJECTIVES: Intravenous (IV) calcium salts are routinely recommended as a cardio-protective therapy in the emergency treatment of severe hyperkalemia. However, this recommendation is supported by a low level of evidence and is anecdotal. The aim of this study is to determine the effectiveness of IV Calcium (Ca) gluconate in the treatment of hyperkalemia. MATERIALS AND METHODS: Patients with hyperkalemia and with the electrocardiogram (ECG) changes due to hyperkalemia over a 1 year period were included in this prospective observational study. Patients’ ECGs were measured, before and after IV Ca-gluconate treatment and after normalization of potassium levels. Wilcoxon test and McNemar's test were used to compare the ECG parameters before and after Ca-gluconate therapy. RESULTS: The mean potassium value of 111 patients who met the inclusion criteria was 7.1 ± 0.6 mmol/l. In this study, a total of 243 ECG pathology related to hyperkalemia, 79 of which included main rhythm disorders, and the remaining 164 were nonrhythm disorders in ECG parameters, were analyzed. No statistically significant changes were determined in patients’ nonrhythm ECG disorders with IV Ca-gluconate treatment (P = 0.125). However, nine of the 79 main rhythm disorders due to hyperkalemia improved with calcium gluconate treatment and this change was statistically significant (P < 0.004). CONCLUSION: IV Ca-gluconate therapy was found to be effective, albeit to a limited degree, in main rhythm ECG disorders due to hyperkalemia, but it was not found to be effective in nonrhythm ECG disorders due to hyperkalemia. Therefore, Ca-gluconate may be effective only in the main rhythm disorders due to hyperkalemia.","PeriodicalId":46536,"journal":{"name":"Turkish Journal of Emergency Medicine","volume":"108 1","pages":"75 - 82"},"PeriodicalIF":0.9,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81334187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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Turkish Journal of Emergency Medicine
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