Pub Date : 2019-12-01DOI: 10.1097/JOM.0000000000001710
J. Thakar, T. Thatcher, M. Smith, C. Woeller, D. Walker, M. Utell, P. Hopke, Timothy M Mallon, Pamela L Krahl, Patricia Rohrbeck, Y. Go, Dean P. Jones, K. Uppal
OBJECTIVE To develop a computational approach to link clinical outcomes with environmental exposures and molecular variations measured in Department of Defense (DOD) serum-repository samples. METHODS International Classification of Diseases, Ninth Division codes which corresponded to cardiopulmonary symptoms for service personnel were selected to test for associations with deployment-related inhalation hazards and metabolomics, micro-RNA, cytokine, plasma markers, and environmental exposure analyses for corresponding samples. xMWAS and Mummichog were used for integrative network and pathway analysis. RESULTS Comparison between 41 personnel exhibiting new cardio-pulmonary diagnoses after deployment start-date to 25 personnel exhibiting no symptoms identified biomarkers associated with cardiopulmonary conditions. Integrative network and pathway analysis showed communities of clinical, molecular, and environmental markers associated with fatty acid, lipid, nucleotide, and amino acid metabolism pathways. CONCLUSIONS The current proof of principle study establishes a computational framework for integrative analysis of deployment-related exposures, molecular responses, and health outcomes.
{"title":"Integrative Network Analysis Linking Clinical Outcomes With Environmental Exposures and Molecular Variations in Service Personnel Deployed to Balad and Bagram.","authors":"J. Thakar, T. Thatcher, M. Smith, C. Woeller, D. Walker, M. Utell, P. Hopke, Timothy M Mallon, Pamela L Krahl, Patricia Rohrbeck, Y. Go, Dean P. Jones, K. Uppal","doi":"10.1097/JOM.0000000000001710","DOIUrl":"https://doi.org/10.1097/JOM.0000000000001710","url":null,"abstract":"OBJECTIVE\u0000To develop a computational approach to link clinical outcomes with environmental exposures and molecular variations measured in Department of Defense (DOD) serum-repository samples.\u0000\u0000\u0000METHODS\u0000International Classification of Diseases, Ninth Division codes which corresponded to cardiopulmonary symptoms for service personnel were selected to test for associations with deployment-related inhalation hazards and metabolomics, micro-RNA, cytokine, plasma markers, and environmental exposure analyses for corresponding samples. xMWAS and Mummichog were used for integrative network and pathway analysis.\u0000\u0000\u0000RESULTS\u0000Comparison between 41 personnel exhibiting new cardio-pulmonary diagnoses after deployment start-date to 25 personnel exhibiting no symptoms identified biomarkers associated with cardiopulmonary conditions. Integrative network and pathway analysis showed communities of clinical, molecular, and environmental markers associated with fatty acid, lipid, nucleotide, and amino acid metabolism pathways.\u0000\u0000\u0000CONCLUSIONS\u0000The current proof of principle study establishes a computational framework for integrative analysis of deployment-related exposures, molecular responses, and health outcomes.","PeriodicalId":46545,"journal":{"name":"International Journal of Occupational and Environmental Medicine","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82055789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-01DOI: 10.1097/JOM.0000000000001747
Huijun Zhao, Yi-wen Lu, Hong Chen, X. Kuang
W e read with respect the manuscript by Arnetz et al investigating the potential association between work environment, serum dehydroepiandrosteronesulphate (DHEA-S) and interleukin-6 (IL6), and patient care outcomes. Their study demonstrated the DHEA-S and/or IL-6 as biomarkers of nurse stress and patient outcome. However, we have some comments on the biomarker determination. Firstly, some descriptions that make confusion should be clarified. In Section ‘‘study procedure,’’ blood samples were frozen and stored at –80 8C after collection, we guess the samples kept for further analysis should be serum rather than blood. In Tables 2 and 3, the results of DHEA-S and IL-6 were listed without unit. In Section
{"title":"Biomarkers Determination of the Nurse in Various Work Environments.","authors":"Huijun Zhao, Yi-wen Lu, Hong Chen, X. Kuang","doi":"10.1097/JOM.0000000000001747","DOIUrl":"https://doi.org/10.1097/JOM.0000000000001747","url":null,"abstract":"W e read with respect the manuscript by Arnetz et al investigating the potential association between work environment, serum dehydroepiandrosteronesulphate (DHEA-S) and interleukin-6 (IL6), and patient care outcomes. Their study demonstrated the DHEA-S and/or IL-6 as biomarkers of nurse stress and patient outcome. However, we have some comments on the biomarker determination. Firstly, some descriptions that make confusion should be clarified. In Section ‘‘study procedure,’’ blood samples were frozen and stored at –80 8C after collection, we guess the samples kept for further analysis should be serum rather than blood. In Tables 2 and 3, the results of DHEA-S and IL-6 were listed without unit. In Section","PeriodicalId":46545,"journal":{"name":"International Journal of Occupational and Environmental Medicine","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82673505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-22DOI: 10.1097/JOM.0000000000001787
Jussi Tanskanen
OBJECTIVES Study examines the curvilinear associations of working time dimensions (working hours, time pressure, work schedules, and control of work time and pace) on psychological and somatic symptoms. METHODS Representative Finnish Quality-of-Work-Life Surveys conducted in 2003, 2008 and 2013 were restricted to those (N = 11,165) regularly working over 10 h/week with more than one-year tenure in their job. Generalised additive models were utilised in analysis. RESULTS Working hours had U-shaped relationships with psychosomatic symptoms, while time pressure had a threshold effect. Work pace control had linear effect. The effects of work time control and work schedules were insignificant. There were interaction effects between working time dimensions. CONCLUSIONS Organisations should acknowledge the dynamics of working time dimensions. Notably, time pressure has a hazardous relation to psychosomatic symptoms, but working pace control can buffer the negative effect.
{"title":"Bending Work Time: Curvilinear Relationship Between Working Time Dimensions and Psychological and Somatic Symptoms.","authors":"Jussi Tanskanen","doi":"10.1097/JOM.0000000000001787","DOIUrl":"https://doi.org/10.1097/JOM.0000000000001787","url":null,"abstract":"OBJECTIVES\u0000Study examines the curvilinear associations of working time dimensions (working hours, time pressure, work schedules, and control of work time and pace) on psychological and somatic symptoms.\u0000\u0000\u0000METHODS\u0000Representative Finnish Quality-of-Work-Life Surveys conducted in 2003, 2008 and 2013 were restricted to those (N = 11,165) regularly working over 10 h/week with more than one-year tenure in their job. Generalised additive models were utilised in analysis.\u0000\u0000\u0000RESULTS\u0000Working hours had U-shaped relationships with psychosomatic symptoms, while time pressure had a threshold effect. Work pace control had linear effect. The effects of work time control and work schedules were insignificant. There were interaction effects between working time dimensions.\u0000\u0000\u0000CONCLUSIONS\u0000Organisations should acknowledge the dynamics of working time dimensions. Notably, time pressure has a hazardous relation to psychosomatic symptoms, but working pace control can buffer the negative effect.","PeriodicalId":46545,"journal":{"name":"International Journal of Occupational and Environmental Medicine","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72833255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-20DOI: 10.1097/JOM.0000000000001786
Seyoung Lee, J. Yoon, Y. Kang, Taeshik Kim, J. Koo, Mo-Yeol Kang
OBJECTIVE To investigate the relationship between musculoskeletal pain (MSP) and ill-health retirement (IHR) and modifying role of socioeconomic factors. METHODS The data used were samples from the Korean Longitudinal Study of Aging from 2006 to 2014. IHR was defined as retirement due to health problems before regular retirement age. Hazard ratio (HR) was calculated using Cox proportional hazards model to determine the effects of MSP and covariance on IHR. RESULTS People who have "any site of pain" were more likely to experience IHR than people with no pain. In the subgroup analysis, Risk of IHR due to MSP was higher in the 60 s, white-collar, and high-income earners than the other groups. CONCLUSIONS MSP has a substantial negative impact on labor force participation, and there was a clear effect modification of socioeconomic status on IHR risk.
{"title":"Effect of Socioeconomic Factors on the Relationship Between Musculoskeletal Pain and Ill-Health Retirement in Korea: Results from the Korean Longitudinal Study of Aging.","authors":"Seyoung Lee, J. Yoon, Y. Kang, Taeshik Kim, J. Koo, Mo-Yeol Kang","doi":"10.1097/JOM.0000000000001786","DOIUrl":"https://doi.org/10.1097/JOM.0000000000001786","url":null,"abstract":"OBJECTIVE\u0000To investigate the relationship between musculoskeletal pain (MSP) and ill-health retirement (IHR) and modifying role of socioeconomic factors.\u0000\u0000\u0000METHODS\u0000The data used were samples from the Korean Longitudinal Study of Aging from 2006 to 2014. IHR was defined as retirement due to health problems before regular retirement age. Hazard ratio (HR) was calculated using Cox proportional hazards model to determine the effects of MSP and covariance on IHR.\u0000\u0000\u0000RESULTS\u0000People who have \"any site of pain\" were more likely to experience IHR than people with no pain. In the subgroup analysis, Risk of IHR due to MSP was higher in the 60 s, white-collar, and high-income earners than the other groups.\u0000\u0000\u0000CONCLUSIONS\u0000MSP has a substantial negative impact on labor force participation, and there was a clear effect modification of socioeconomic status on IHR risk.","PeriodicalId":46545,"journal":{"name":"International Journal of Occupational and Environmental Medicine","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82042124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-20DOI: 10.1097/JOM.0000000000001785
B. Mayer, Steffen Guenther
OBJECTIVE The aim of this longitudinal retrospective study was to identify possible determinants of absence from work in a productive company in Tyrol/Austria. METHODS Data of 974 workers and employees were analyzed. Times of absence were analyzed descriptively and the impact of their possible determinants was evaluated by means of hierarchical linear models. RESULTS The extent of absence was constant during the observed period, i.e. former measures of health promotion were not effective. The number of sick days was, among others, significantly associated with working status (worker/employee, p < 0.001) and the company's department (commercial division, p < 0.001). CONCLUSIONS A number of determinants for increased operational absence were identified. These may be considered specifically when adapting workplace health management. Since the observed times of absence mostly not normally distributed, future reports shall use nonparametric methods.
{"title":"Common Determinants of Absence from Work in Employees and Workers: A Retrospective Analysis of Personal and Economical Aspects.","authors":"B. Mayer, Steffen Guenther","doi":"10.1097/JOM.0000000000001785","DOIUrl":"https://doi.org/10.1097/JOM.0000000000001785","url":null,"abstract":"OBJECTIVE\u0000The aim of this longitudinal retrospective study was to identify possible determinants of absence from work in a productive company in Tyrol/Austria.\u0000\u0000\u0000METHODS\u0000Data of 974 workers and employees were analyzed. Times of absence were analyzed descriptively and the impact of their possible determinants was evaluated by means of hierarchical linear models.\u0000\u0000\u0000RESULTS\u0000The extent of absence was constant during the observed period, i.e. former measures of health promotion were not effective. The number of sick days was, among others, significantly associated with working status (worker/employee, p < 0.001) and the company's department (commercial division, p < 0.001).\u0000\u0000\u0000CONCLUSIONS\u0000A number of determinants for increased operational absence were identified. These may be considered specifically when adapting workplace health management. Since the observed times of absence mostly not normally distributed, future reports shall use nonparametric methods.","PeriodicalId":46545,"journal":{"name":"International Journal of Occupational and Environmental Medicine","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82572295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-19DOI: 10.1097/JOM.0000000000001781
Yongjoo Kim, M. Zaitsu, K. Tsuno, Xiaoyu Li, Sunmin Lee, S. Jang, I. Kawachi
OBJECTIVE To examine the association between occupational class and high-sensitivity C-reactive protein (hsCRP) in Korean workers. METHODS We used a nationally representative sample of Koreans (n = 2,591) aged 19-65 years from the 2015 Korea National Health and Nutrition Examination Survey. The concentration of hsCRP (mg/L) was assessed by a high sensitivity immunoturbidimetric assay. Current occupation was categorized as: white-collar (managers/professionals), pink-collar (clerks/service/sales), blue-collar (craft/equipment/machine-assembling, agricultural/forestry/fishery, and elementary-level labor), or unemployed. Cross-sectional linear regression models adjusted for sociodemographic/work-related/health conditions and behaviors. RESULTS Compared with blue-collar workers, white-collar workers showed significantly higher levels of hsCRP ( = 0.16, 95% CI: 0.02, 0.30) after adjusting for all covariates, whereby the pattern was more pronounced among professionals. However, the association was not significant for unemployed and pink-collar workers. CONCLUSIONS Findings suggest that Korean white-collar workers, particularly professionals, have elevated levels of inflammation.
{"title":"Occupational Differences in C-Reactive Protein Among Working-age Adults in South Korea.","authors":"Yongjoo Kim, M. Zaitsu, K. Tsuno, Xiaoyu Li, Sunmin Lee, S. Jang, I. Kawachi","doi":"10.1097/JOM.0000000000001781","DOIUrl":"https://doi.org/10.1097/JOM.0000000000001781","url":null,"abstract":"OBJECTIVE\u0000To examine the association between occupational class and high-sensitivity C-reactive protein (hsCRP) in Korean workers.\u0000\u0000\u0000METHODS\u0000We used a nationally representative sample of Koreans (n = 2,591) aged 19-65 years from the 2015 Korea National Health and Nutrition Examination Survey. The concentration of hsCRP (mg/L) was assessed by a high sensitivity immunoturbidimetric assay. Current occupation was categorized as: white-collar (managers/professionals), pink-collar (clerks/service/sales), blue-collar (craft/equipment/machine-assembling, agricultural/forestry/fishery, and elementary-level labor), or unemployed. Cross-sectional linear regression models adjusted for sociodemographic/work-related/health conditions and behaviors.\u0000\u0000\u0000RESULTS\u0000Compared with blue-collar workers, white-collar workers showed significantly higher levels of hsCRP ( = 0.16, 95% CI: 0.02, 0.30) after adjusting for all covariates, whereby the pattern was more pronounced among professionals. However, the association was not significant for unemployed and pink-collar workers.\u0000\u0000\u0000CONCLUSIONS\u0000Findings suggest that Korean white-collar workers, particularly professionals, have elevated levels of inflammation.","PeriodicalId":46545,"journal":{"name":"International Journal of Occupational and Environmental Medicine","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90225430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-19DOI: 10.1097/JOM.0000000000001779
M. Diebig, N. Dragano, U. Körner, T. Lunau, I. C. Wulf, P. Angerer
OBJECTIVE The rapid development of technology is changing working conditions of many employees. With this, appropriate measurement instruments to capture work-related psychosocial risks to create healthy working conditions are becoming more and more important. Therefore, we developed and validated a questionnaire to assess stressors in work settings which are characterized by a high degree of digitization. METHOD The validation was based on two independent studies with data collected in four subsamples. All participants were asked about their working conditions and health-related topics using online questionnaires. RESULTS The resulting 16-item questionnaire consists of five scales: work load, boundary permeability, participation, leader support, and usability. CONCLUSIONS The results show that the five identified stressors showed acceptable to good values with regard to reliability (internal consistencies, test-retest reliabilities, and interrater agreement) as well as (convergent and concurrent) validity.
{"title":"Development and Validation of a Questionnaire to Measure Psychosocial Work Stressors in Modern Working Environments.","authors":"M. Diebig, N. Dragano, U. Körner, T. Lunau, I. C. Wulf, P. Angerer","doi":"10.1097/JOM.0000000000001779","DOIUrl":"https://doi.org/10.1097/JOM.0000000000001779","url":null,"abstract":"OBJECTIVE\u0000The rapid development of technology is changing working conditions of many employees. With this, appropriate measurement instruments to capture work-related psychosocial risks to create healthy working conditions are becoming more and more important. Therefore, we developed and validated a questionnaire to assess stressors in work settings which are characterized by a high degree of digitization.\u0000\u0000\u0000METHOD\u0000The validation was based on two independent studies with data collected in four subsamples. All participants were asked about their working conditions and health-related topics using online questionnaires.\u0000\u0000\u0000RESULTS\u0000The resulting 16-item questionnaire consists of five scales: work load, boundary permeability, participation, leader support, and usability.\u0000\u0000\u0000CONCLUSIONS\u0000The results show that the five identified stressors showed acceptable to good values with regard to reliability (internal consistencies, test-retest reliabilities, and interrater agreement) as well as (convergent and concurrent) validity.","PeriodicalId":46545,"journal":{"name":"International Journal of Occupational and Environmental Medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84430861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-19DOI: 10.1097/JOM.0000000000001782
Daniela Renger, M. Miché, A. Casini
OBJECTIVE The present research systematically investigates the role of recognition experiences at work as a protective factor for burnout. METHOD In two cross-sectional studies (N = 328 and N = 220) with employees we measured via online questionnaires three forms of recognition (achievement-based social esteem, equality-based respect and need-based care) from coworkers and supervisors as predictors and burnout among employees as outcome. RESULTS Using multiple regression analyses, study 1 provided initial evidence that both supervisor and coworker recognition were negatively associated with employees' burnout. Study 2 further demonstrated that whereas respect experiences were especially crucial for lowering emotional exhaustion, care was primarily linked to reduced depersonalization and esteem to heightened personal accomplishment. CONCLUSION We discuss how positive recognition experiences can be fostered in organizations in order to buffer the negative effects burnout can cause.
{"title":"Professional Recognition At Work: The protective Role of Esteem, Respect and Care For Burnout Among Employees.","authors":"Daniela Renger, M. Miché, A. Casini","doi":"10.1097/JOM.0000000000001782","DOIUrl":"https://doi.org/10.1097/JOM.0000000000001782","url":null,"abstract":"OBJECTIVE\u0000The present research systematically investigates the role of recognition experiences at work as a protective factor for burnout.\u0000\u0000\u0000METHOD\u0000In two cross-sectional studies (N = 328 and N = 220) with employees we measured via online questionnaires three forms of recognition (achievement-based social esteem, equality-based respect and need-based care) from coworkers and supervisors as predictors and burnout among employees as outcome.\u0000\u0000\u0000RESULTS\u0000Using multiple regression analyses, study 1 provided initial evidence that both supervisor and coworker recognition were negatively associated with employees' burnout. Study 2 further demonstrated that whereas respect experiences were especially crucial for lowering emotional exhaustion, care was primarily linked to reduced depersonalization and esteem to heightened personal accomplishment.\u0000\u0000\u0000CONCLUSION\u0000We discuss how positive recognition experiences can be fostered in organizations in order to buffer the negative effects burnout can cause.","PeriodicalId":46545,"journal":{"name":"International Journal of Occupational and Environmental Medicine","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73486977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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