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Cytomegalovirus (CMV) seroprevalence among women at childbearing age, maternal and congenital CMV infection: policy implications of a descriptive, retrospective, community-based study. 育龄妇女巨细胞病毒(CMV)血清阳性率、孕产妇和先天性巨细胞病毒感染:一项描述性、回顾性、基于社区的研究对政策的影响。
IF 3.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2023-04-25 DOI: 10.1186/s13584-023-00566-9
Assaf Ben Shoham, Yechiel Schlesinger, Ian Miskin, Ziva Kalderon, Rachel Michaelson-Cohen, Yonit Wiener-Well
<p><strong>Background: </strong>Maternal CMV infection during pregnancy, either primary or non-primary, may be associated with fetal infection and long-term sequelae. While guidelines recommend against it, screening for CMV in pregnant women is a prevalent clinical practice in Israel. Our aim is to provide updated, local, clinically relevant, epidemiological information about CMV seroprevalence among women at childbearing age, the incidence of maternal CMV infection during pregnancy and the prevalence of congenital CMV (cCMV), as well as to provide information about the yield of CMV serology testing.</p><p><strong>Methods: </strong>We performed a descriptive, retrospective study of women at childbearing age who were members of Clalit Health Services in the district of Jerusalem and had at least one gestation during the study period (2013-2019). We utilized serial serology tests to determine CMV serostatus at baseline and at pre/periconception and identified temporal changes in CMV serostatus. We then conducted a sub-sample analysis integrating inpatient data on newborns of women who gave birth in a single large medical center. cCMV was defined as either positive urine CMV-PCR test in a sample collected during the first 3 weeks of life, neonatal diagnosis of cCMV in the medical records, or prescription of valganciclovir during the neonatal period.</p><p><strong>Results: </strong>The study population Included 45,634 women with 84,110 associated gestational events. Initial CMV serostatus was positive in 89% women, with variation across different ethno-socioeconomic subgroups. Based on consecutive serology tests, the detected incidence rate of CMV infection was 2/1000 women follow-up years, among initially seropositive women, and 80/1000 women follow-up years, among initially seronegative women. CMV infection in pregnancy was identified among 0.2% of women who were seropositive at pre/periconception and among 10% of women who were seronegative. In a subsample, which included 31,191 associated gestational events, we identified 54 newborns with cCMV (1.9/1000 live births). The prevalence of cCMV among newborns of women who were seropositive at pre/periconception was lower than among newborns of women who were seronegative (2.1 vs. 7.1/1000). Frequent serology tests among women who were seronegative at pre/periconception detected most primary CMV infections in pregnancy that resulted in cCMV (21/24). However, among women who were seropositive, serology tests prior to birth detected none of the non-primary infections that resulted in cCMV (0/30).</p><p><strong>Conclusions: </strong>In this retrospective community-based study among women of childbearing age characterized by multiparity and high seroprevalence of CMV, we find that consecutive CMV serology testing enabled to detect most primary CMV infections in pregnancy that led to cCMV in newborns but failed to detect non-primary CMV infections in pregnancy. Conducting CMV serology tests among seropositi
背景:妊娠期母体 CMV 感染(无论是原发性还是非原发性)可能与胎儿感染和长期后遗症有关。虽然指导原则建议不要对孕妇进行 CMV 筛查,但这在以色列的临床实践中非常普遍。我们的目的是提供有关育龄妇女中 CMV 血清流行率、孕期母体 CMV 感染率和先天性 CMV(cCMV)流行率的最新本地临床流行病学信息,并提供有关 CMV 血清学检测结果的信息:我们对耶路撒冷地区 Clalit 卫生服务机构的育龄妇女进行了一项描述性回顾研究,这些妇女在研究期间(2013-2019 年)至少有过一次妊娠。我们利用序列血清学测试来确定基线和孕前/围产期的 CMV 血清状态,并确定 CMV 血清状态的时间变化。cCMV 的定义是:出生后 3 周内采集的尿液样本中 CMV-PCR 检测呈阳性、病历中新生儿诊断为 cCMV 或新生儿期开具了缬更昔洛韦处方:研究对象包括 45,634 名妇女和 84,110 例相关妊娠事件。89%的妇女最初的 CMV 血清呈阳性,不同种族-社会经济亚群之间存在差异。根据连续的血清学检测,在最初血清呈阳性的妇女中,CMV 感染的检测发病率为 2/1000,在最初血清呈阴性的妇女中,CMV 感染的检测发病率为 80/1000。在孕前/围产期血清反应呈阳性的妇女中,有 0.2%的人在怀孕期间感染了 CMV,而在血清反应呈阴性的妇女中,有 10%的人在怀孕期间感染了 CMV。在包括 31 191 例相关妊娠事件的子样本中,我们发现 54 名新生儿感染了巨细胞病毒(1.9/1000 例活产)。孕前/围产期血清反应阳性妇女的新生儿中 cCMV 感染率低于血清反应阴性妇女的新生儿(2.1 对 7.1/1000)。在孕前/围产期血清学检测呈阴性的妇女中,通过频繁的血清学检测发现了大多数导致 cCMV 的妊娠期原发性 CMV 感染(21/24)。然而,在血清反应呈阳性的妇女中,分娩前的血清检测没有发现导致 cCMV 的非原发性感染(0/30):在这项以社区为基础的回顾性研究中,我们发现在多胎妊娠和 CMV 血清高流行率的育龄妇女中,连续的 CMV 血清学检测能够发现大多数导致新生儿患上 cCMV 的妊娠期原发性 CMV 感染,但未能发现妊娠期非原发性 CMV 感染。尽管有指南建议,但在血清反应阳性的妇女中进行 CMV 血清学检测并没有临床价值,而且成本高昂,还会带来更多的不确定性和困扰。因此,我们建议不要对之前血清学检测呈阳性的妇女进行常规 CMV 血清学检测。我们建议仅在已知血清阴性或血清状态不明的妇女怀孕前进行 CMV 血清学检测。
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引用次数: 0
The COVID-19 Israeli tapestry: the intersectionality health equity challenge. 2019冠状病毒病以色列挂毯:交叉卫生公平挑战。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2023-04-25 DOI: 10.1186/s13584-023-00567-8
Efrat Shadmi, Mohammad Khatib, Sivan Spitzer

Background: COVID-19 is disproportionately affecting disadvantaged populations, with greater representation and worse outcomes in low socioeconomic and minority populations, and in persons from marginalized groups. General health care system approaches to inequity reduction (i.e., the minimization of differences in health and health care which are considered unfair or unjust), address the major social determinants of health, such as low income, ethnic affiliation or remote place of residents. Yet, to effectively reduce inequity there is a need for a multifactorial consideration of the aspects that intersect and generate significant barriers to effective care that can address the unique situations that people face due to their gender, ethnicity and socioeconomic situation.

Main body: To address the health equity challenges of diverse population groups in Israel, we propose to adopt an intersectional approach, allowing to better identify the needs and then better tailor the infection prevention and control modalities to those who need them the most. We focus on the two main ethnic - cultural-religious minority groups, that of Arab Palestinian citizens of Israel and Jewish ultra-orthodox (Haredi) communities. Additionally, we address the unique needs of persons with severe mental illness who often experience an intersection of clinical and sociodemographic risks.

Conclusions: This perspective highlights the need for responses to COVID-19, and future pandemic or global disasters, that adopt the unique lens of intersectionality and equity. This requires that the government and health system create multiple messages, interventions and policies which ensure a person and community tailored approach to meet the needs of persons from diverse linguistic, ethnic, religious, socioeconomic and cultural backgrounds. Under-investment in intersectional responses will lead to widening of gaps and a disproportionate disease and mortality burden on societies' most vulnerable groups.

背景:2019冠状病毒病对弱势群体的影响尤为严重,社会经济地位低的人群和少数群体以及边缘群体的代表性更大,结果也更糟。减少不公平现象的一般卫生保健系统方法(即,尽量减少被认为不公平或不公正的卫生和卫生保健方面的差异),处理卫生的主要社会决定因素,如低收入、种族关系或居民的偏远地区。然而,为了有效减少不平等,需要多因素地考虑相互交叉并对有效护理产生重大障碍的各个方面,这些方面可以解决人们因其性别、种族和社会经济状况而面临的独特情况。主体:为了应对以色列不同人口群体的卫生公平挑战,我们建议采取交叉方法,以便更好地确定需求,然后更好地为最需要的人量身定制感染预防和控制方式。我们关注两个主要的民族-文化-宗教少数群体,即以色列的阿拉伯巴勒斯坦公民和犹太极端正统派(Haredi)社区。此外,我们解决严重精神疾病患者的独特需求,他们经常经历临床和社会人口风险的交叉。结论:这一观点强调,应对COVID-19以及未来的大流行或全球灾害,需要采用独特的交叉性和公平性视角。这就要求政府和卫生系统制定多种信息、干预措施和政策,确保采取适合个人和社区的方法,以满足来自不同语言、种族、宗教、社会经济和文化背景的人的需求。对交叉对策的投资不足将导致差距扩大,并对社会中最脆弱群体造成不成比例的疾病和死亡率负担。
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引用次数: 0
Understanding and addressing populations whose prior experience has led to mistrust in healthcare. 了解和解决那些先前经历导致对医疗保健不信任的人群。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2023-04-21 DOI: 10.1186/s13584-023-00565-w
Dan Even, Shifra Shvarts

Background: Policy makers need to maintain public trust in healthcare systems in order to foster citizen engagement in recommended behaviors and treatments. The importance of such commitment has been highlighted by the recent COVID-19 pandemic. Central to public trust is the extent of the accountability of health authorities held responsible for long-term effects of past treatments. This paper addresses the topic of manifestations of trust among patients damaged by radiation treatments for ringworm.

Methods: For this mixed-methods case study (quan/qual), we sampled 600 files of Israeli patients submitting claims to the National Center for Compensation of Scalp Ringworm Victims in the years 1995-2014, following damage from radiation treatments received between 1946 and 1960 in Israel and/or abroad. Qualitative data were analyzed with descriptive statistics, and correlations were analyzed with chi-square tests. Verbal data were analyzed by the use of systematic content analysis.

Results: Among 527 patients whose files were included in the final analysis, 42% held authorities responsible. Assigning responsibility to authorities was more prevalent among claimants born in Israel than among those born and treated abroad (χ2 = 6.613, df = 1, p = 0.01), claimants reporting trauma (χ2 = 4.864, df = 1, p = 0.027), and claimants living in central cities compared with those in suburban areas (χ2 = 18.859, df = 6, p < 0.01). Men, younger claimants, patients with a psychiatric diagnosis, and patients from minority populations expressed mistrust in health regulators.

Conclusions: Examining populations' perceived trust in healthcare institutions and tailoring health messages to vulnerable populations can promote public trust in healthcare systems.

背景:决策者需要维持公众对医疗保健系统的信任,以促进公民参与推荐的行为和治疗。最近的COVID-19大流行凸显了这种承诺的重要性。公众信任的核心是对过去治疗的长期影响负责的卫生当局的问责程度。本文讨论了放射治疗损伤的癣患者之间的信任表现。方法:在这个混合方法的案例研究中,我们抽样了1995-2014年期间向国家头皮癣受害者赔偿中心提交索赔的600名以色列患者,这些患者在1946年至1960年期间在以色列和/或国外接受放射治疗造成的损伤。定性资料采用描述性统计分析,相关性采用卡方检验分析。口头资料采用系统的内容分析法进行分析。结果:在纳入最终分析的527例患者中,42%的患者认为当局有责任。在以色列出生的索赔人比在国外出生和治疗的索赔人更普遍地将责任分配给当局(χ2 = 6.613, df = 1, p = 0.01),索赔人报告创伤(χ2 = 4.864, df = 1, p = 0.027),居住在中心城市的索赔人比居住在郊区的索赔人更普遍(χ2 = 18.859, df = 6, p)。检查民众对卫生保健机构的感知信任,并为弱势群体量身定制卫生信息,可以促进公众对卫生保健系统的信任。
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引用次数: 1
A 10-year comparison of short versus long-term court-ordered psychiatric hospitalization: a follow-up study. 一项为期10年的短期与长期法院命令精神病院的比较:一项随访研究。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2023-04-20 DOI: 10.1186/s13584-023-00561-0
Daniel Argo, Khaled Daibas, Igor Barash, Moshe Z Abramowitz
<p><strong>Background: </strong>The Israel Mental Health Act of 1991 stipulates a process for court-ordered involuntary psychiatric hospitalization. As in many Western countries, this process is initiated when an individual is deemed "not criminally responsible by reason of mental disorder (NCR-MD)" or "incompetent to stand trial (IST)." A patient thus hospitalized may be discharged by the district psychiatric committee (DPC). The decision rendered by the DPC is guided by an amendment to the Mental Health Act that states that the length of the hospitalization should be in accordance with the maximum time of incarceration associated with the alleged crime. Little empirical research has been devoted to the psychiatric, medical, and social outcome of short versus long-term hospitalization under court order.</p><p><strong>Methods: </strong>In our study we examined the outcomes of court-ordered criminal commitments over a 10-year period (2005-2015) at the Jerusalem Mental Health Center with a catchment area of 1.5 million. We found 136 cases (between the ages of 18 and 60) of criminal commitments during that period and used the average length of hospitalization, 205 days, as a cutoff point between short and long stays. We compared the outcomes of short and long hospitalizations of discharged patients using a follow-up phone survey (at least 7 years post-discharge) and data extracted from the Israel National Register to include recidivism, patient satisfaction and trust in the system, readmission, and demise.</p><p><strong>Results: </strong>We found no statistically significant difference between short-term and long-term hospitalizations for reducing instances of re-hospitalization (p = 0.889) and recidivism (p = 0.54), although there was a slight trend toward short-term hospitalization vis-à-vis reduced recidivism. We did not find a statistical difference in mortality or incidents of suicide between the two groups, but the absolute numbers are higher than expected in both of them. Moreover, our survey showed that short-term hospitalization inspired more trust in the legal process (conduct of the DPC), in pharmacological treatment satisfaction, and in understanding the NCR-MD as a step toward avoiding future hospitalization and that it resulted in a higher level of patient satisfaction.</p><p><strong>Conclusions: </strong>The results we present show that as far as recidivism and readmission are concerned, there is no evidence to suggest that there is an advantage to long-term hospitalization. Although there may be unmeasured variables not investigated in the present study that might have contributed to the discrepancy between long- and short-term hospitalization, we believe that longer hospitalizations may not serve the intended treatment purpose. Additionally, the high cost of long-term hospitalization and overcrowded wards are obviously major practical drawbacks. The impact of the clinical outcomes should be reflected in medico-legal legislation and
背景:1991年《以色列精神卫生法》规定了法院命令非自愿精神病住院的程序。与许多西方国家一样,当一个人被认为“由于精神障碍(NCR-MD)而不承担刑事责任”或“无法接受审判(IST)”时,就会启动这一程序。因此住院的病人可由区精神病委员会(DPC)批准出院。DPC作出的决定以《精神卫生法》修正案为指导,该修正案规定,住院时间应与与所指控罪行有关的最长监禁时间相一致。很少有实证研究专门针对法院命令下短期与长期住院治疗的精神病学、医学和社会结果。方法:在我们的研究中,我们检查了耶路撒冷心理健康中心(集水区150万)10年间(2005-2015年)法院下令犯罪的结果。我们发现在此期间有136例(年龄在18至60岁之间)犯罪行为,并使用平均住院时间205天作为短期和长期住院的分界点。我们通过随访电话调查(出院后至少7年)比较出院患者短期和长期住院的结果,并从以色列国家登记册中提取数据,包括再犯、患者满意度和对系统的信任、再入院和死亡。结果:我们发现短期和长期住院在减少再次住院(p = 0.889)和再犯(p = 0.54)方面没有统计学上的显著差异,尽管短期住院与-à-vis减少再犯有轻微的趋势。我们没有发现两组在死亡率或自杀事件上有统计学差异,但绝对数字都高于预期。此外,我们的调查显示,短期住院激发了对法律程序(DPC的行为),药理治疗满意度以及将NCR-MD理解为避免未来住院的一步的更多信任,并导致更高水平的患者满意度。结论:我们目前的研究结果表明,就累犯和再入院而言,没有证据表明长期住院有优势。虽然在本研究中可能存在未测量的变量,这些变量可能导致长期和短期住院之间的差异,但我们认为长期住院可能无法达到预期的治疗目的。此外,长期住院费用高和病房过度拥挤显然是主要的实际缺点。临床结果的影响应反映在医疗法律立法中,特别是法院命令的住院治疗中。
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引用次数: 0
The COVID-19 pandemic posed many dilemmas for policymakers, which sometimes resulted in unprecedented decision-making. 2019冠状病毒病大流行给决策者带来了许多困境,有时导致前所未有的决策。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2023-04-18 DOI: 10.1186/s13584-023-00564-x
Nachman Ash, Noa Triki, Ruth Waitzberg

Background: The COVID-19 pandemic evolved through five phases, beginning with 'the great threat', then moving through 'the emergence of variants', 'vaccines euphoria', and 'the disillusionment', and culminating in 'a disease we can live with'. Each phase required a different governance response. With the progress of the pandemic, data were collected, evidence was created, and health technology was developed and disseminated. Policymaking shifted from protecting the population by limiting infections with non-pharmaceutical interventions to controlling the pandemic by prevention of severe disease with vaccines and drugs for those infected. Once the vaccine became available, the state started devolving the responsibility for the individual's health and behavior.

Main body: Each phase of the pandemic posed new and unique dilemmas for policymakers, which resulted in unprecedented decision-making. Restrictions to individual's rights such as a lockdown or the 'Green Pass policy' were unimaginable before the pandemic. One of the most striking decisions that the Ministry of Health made was approving the third (booster) vaccine dose in Israel, before it was approved by the FDA or any other country. It was possible to make an informed, evidence-based decision due to the availability of reliable and timely data. Transparent communication with the public probably promoted adherence to the booster dose recommendation. The boosters made an important contribution to public health, even though their uptake was less than the uptake for the initial doses. The decision to approve the booster illustrates seven key lessons from the pandemic: health technology is key; leadership is crucial (both political and professional); a single body should coordinate the actions of all stakeholders involved in the response, and these should collaborate closely; policymakers need to engage the public and win their trust and compliance; data are essential to build a suitable response; and nations and international organizations should collaborate in preparing for and responding to pandemics, because viruses travel without borders.

Conclusion: The COVID-19 pandemic posed many dilemmas for policymakers. The lessons learned from the actions taken to deal with them should be incorporated into preparedness for future challenges.

背景:2019冠状病毒病大流行经历了五个阶段,从“巨大威胁”开始,然后经历了“变种的出现”、“疫苗兴奋”和“幻灭”,最后达到“一种我们可以忍受的疾病”。每个阶段都需要不同的治理响应。随着大流行的进展,收集了数据,创造了证据,开发和传播了卫生技术。政策制定从通过非药物干预措施限制感染来保护人口转向通过为感染者接种疫苗和药物预防严重疾病来控制大流行。一旦有了疫苗,国家就开始下放对个人健康和行为的责任。正文:大流行的每个阶段都给决策者带来了新的和独特的困境,从而导致前所未有的决策。对个人权利的限制,如封锁或“绿色通行证政策”,在大流行之前是不可想象的。卫生部做出的最惊人的决定之一是在FDA或任何其他国家批准之前,在以色列批准了第三剂(加强剂)疫苗。由于有可靠和及时的数据,因此有可能做出知情的、基于证据的决定。与公众的透明沟通可能促进了对加强剂量建议的遵守。增强剂对公众健康做出了重要贡献,尽管它们的吸收比最初剂量的吸收要少。批准加强疫苗的决定说明了大流行的七个关键教训:卫生技术是关键;领导力至关重要(无论是政治上的还是专业上的);一个单一的机构应协调参与应对的所有利益攸关方的行动,这些利益攸关方应密切合作;政策制定者需要让公众参与进来,赢得他们的信任和遵从;数据对于制定适当的应对措施至关重要;各国和国际组织应该合作,为流行病做好准备并作出反应,因为病毒是无国界传播的。结论:新冠肺炎大流行给政策制定者带来了许多困境。应对这些挑战所采取的行动所取得的经验教训应纳入应对未来挑战的准备工作中。
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引用次数: 1
"I'm 'just' a community pediatrician" views and challenges of pediatricians working in the community in Israel. “我‘只是’一名社区儿科医生”以色列社区儿科医生的观点和挑战。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2023-04-17 DOI: 10.1186/s13584-023-00563-y
Shulamit Pinchover, Rony Berger-Raanan, Maya Yaari, Mary Rudolf, Lisa Rubin, Dafna Idan-Prusak, Vera Skvirsky, Tirzah Margolin, Hava Gadassi

Background: There are ongoing changes around the world in the training and practice of pediatricians who work in the community. These changes are driven by the understanding that pediatricians are required to provide not only acute primary care but also to address more comprehensive concerns, particularly the 'new morbidities'. The present study examines the professional identity of Israeli pediatricians in the community in light of these changes, the barriers and challenges to their work and professional adaptations in the field.

Methods: We used a mixed-methods approach, collecting the perspectives of 137 pediatricians who work in the community through an anonymous online survey, followed by in-depth semi-structured interviews with 11 community pediatricians.

Results: The survey results show that community pediatricians in Israel have limited knowledge on a variety of developmental, behavioral and emotional issues; that they lack working relationships with medical or other professionals; and are rarely engaged with other community services. Three main themes arose from the interviews that support and deepen the survey results: perceptions of the profession (pediatrics in the community vs. community pediatrics), the stature of pediatricians in the community (during residency, the choice to work in the community, their daily work) and barriers and change in community pediatrics (isolation, limited resources and challenges arising from the nature of community work).

Conclusions: The present study sheds light on the professional identity and the day-to-day challenges and successes of pediatricians working in the community. Continuing medical education, providing a supportive framework and professional community, better resources, more time with patients, and tools and opportunities for professional development would help pediatricians who work in the community to overcome some of these challenges. The research findings reinforce the need for policy change in the field of community pediatrics with a specific community training curriculum, provision of more resources and ongoing support for pediatricians. This requires partnership between the HMOs, the Ministry of Health, the Scientific Council (Israel Medical Association, professional organizations) and NGOs in order to turn individual-level solutions into system-level and policy-changing solutions.

背景:在世界范围内,在社区工作的儿科医生的培训和实践正在发生变化。这些变化是由于人们认识到儿科医生不仅需要提供急性初级保健,还需要解决更全面的问题,特别是“新发病率”。本研究考察了以色列儿科医生在社区的职业认同,根据这些变化,障碍和挑战,他们的工作和专业适应领域。方法:我们采用混合方法,通过匿名在线调查收集了137名在社区工作的儿科医生的观点,随后对11名社区儿科医生进行了深入的半结构化访谈。结果:调查结果显示,以色列的社区儿科医生对各种发育、行为和情绪问题的了解有限;他们缺乏与医疗或其他专业人士的工作关系;很少参与其他社区服务。从支持和深化调查结果的访谈中产生了三个主要主题:对专业的看法(社区儿科与社区儿科),社区儿科医生的地位(住院期间,在社区工作的选择,他们的日常工作)以及社区儿科的障碍和变化(孤立,资源有限和社区工作性质带来的挑战)。结论:本研究揭示了在社区工作的儿科医生的职业认同、日常挑战和成功。继续医学教育,提供一个支持性的框架和专业社区,更好的资源,更多的时间与病人相处,以及专业发展的工具和机会,将帮助在社区工作的儿科医生克服其中一些挑战。研究结果强调需要在社区儿科领域进行政策改革,制定具体的社区培训课程,提供更多的资源,并为儿科医生提供持续的支持。这需要卫生保健组织、卫生部、科学理事会(以色列医学协会、专业组织)和非政府组织之间的伙伴关系,以便将个人层面的解决方案转化为系统层面和改变政策的解决方案。
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引用次数: 0
Rational and irrational vaccine hesitancy. 合理和不合理的疫苗犹豫。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2023-03-28 DOI: 10.1186/s13584-023-00560-1
Manfred S Green

In the paper published recently in this journal, Kumar et al. explained why the key to improved COVID-19 vaccine uptake is to understand societal reactions leading to vaccine hesitancy. They conclude that communications strategies should be tailored to the different phases of vaccine hesitancy. However, within the theoretical framework provided in their paper, vaccine hesitancy should be recognized as having both rational and irrational components. Rational vaccine hesitancy is a natural result of the inherent uncertainties in the potential impact of vaccines in controlling the pandemic. In general, irrational hesitancy is based on baseless information obtained from hearsay and deliberately false information. Risk communication should address both with transparent, evidence-based information. Rational concerns can be allayed by sharing the process in which dilemmas and uncertainties are dealt with by the health authorities. Messages on irrational concerns need to address head on the sources spreading unscientific and unsound information. In both cases, there is a need to develop risk communication that restores trust in the health authorities.

在最近发表在该杂志上的论文中,Kumar等人解释了为什么改善COVID-19疫苗摄取的关键是了解导致疫苗犹豫的社会反应。他们的结论是,传播战略应该针对疫苗犹豫的不同阶段进行调整。然而,在他们的论文提供的理论框架内,应该认识到疫苗犹豫既有合理的成分,也有不合理的成分。合理的疫苗犹豫是疫苗在控制大流行方面潜在影响的固有不确定性的自然结果。一般来说,非理性犹豫是基于从道听途说中获得的毫无根据的信息和故意虚假的信息。风险沟通应通过透明的、基于证据的信息解决这两个问题。通过分享卫生当局处理困境和不确定性的过程,可以减轻合理的关切。有关非理性担忧的信息需要迎头解决传播不科学和不健全信息的来源。在这两种情况下,都需要开展风险沟通,以恢复对卫生当局的信任。
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引用次数: 0
Rethinking the path from evidence to decision-making. 重新思考从证据到决策的路径。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2023-03-27 DOI: 10.1186/s13584-023-00559-8
Alon Rasooly, Eliana Ben-Sheleg, Nadav Davidovitch, Moriah Ellen

Evidence-informed decision-making is increasingly recognized as a standard for policymaking in many fields, including public health. However, many challenges exist in identifying the appropriate evidence, disseminating it to different stakeholders, and implementing it in various settings. The Israel Implementation Science and Policy Engagement Centre (IS-PEC) was established at Ben-Gurion University of the Negev to "bridge the gap" between scientific research and policy. As an illustrative case study, IS-PEC is conducting a scoping review on strategies to engage senior citizens in Israel when developing health policy. In May 2022, IS-PEC brought together international experts and Israeli stakeholders to increase knowledge in the field of evidence-informed policy, develop a research agenda, strengthen international collaborations, and create a community for sharing experience, research, and best practices. Panelists presented the importance of communicating clear, accurate bottom-line messages with the media. Also, they highlighted the once-in-a-generation opportunity to promote the uptake of evidence in public health due to the increased public interest in evidence-informed policymaking post-COVID-19 pandemic and the need to build systems and centers to support the systematic use of evidence. Group discussions focused on various aspects of communication, including challenges and strategies when communicating to policymakers, understanding the nuances of communication between scientists, journalists, and the public, and some ethical issues surrounding data visualization and infographics. Panelists participated in a passionate debate regarding whether and how values play a role when conducting, analyzing, and communicating evidence. Takeaway lessons from the workshop included that going forward, Israel must create lasting systems and a sustainable environment for evidence-informed policy. Novel and interdisciplinary academic programs must be developed to train future policymakers in various fields, including public health, public policy, ethics, communication, social marketing, and infographics. Sustainable professional relationships between journalists, scientists, and policymakers must be fostered and strengthened based on mutual respect and a shared commitment to creating, synthesizing, implementing, and communicating high-quality evidence to serve the public and individual wellbeing.

循证决策日益被认为是包括公共卫生在内的许多领域的决策标准。然而,在确定适当的证据、向不同的利益攸关方传播证据以及在各种环境中实施证据方面存在许多挑战。以色列实施科学与政策参与中心(IS-PEC)在内盖夫的本-古里安大学成立,旨在“弥合科学研究与政策之间的差距”。作为一个说明性案例研究,以色列卫生政策委员会正在对在制定卫生政策时使以色列老年人参与的战略进行范围审查。2022年5月,IS-PEC汇集了国际专家和以色列利益攸关方,以增加在循证政策领域的知识,制定研究议程,加强国际合作,并创建一个分享经验、研究和最佳做法的社区。小组成员提出了与媒体沟通清晰、准确的底线信息的重要性。此外,他们还强调,由于在covid -19大流行后公众对循证决策的兴趣增加,以及需要建立系统和中心以支持系统使用证据,因此这是促进公共卫生证据吸收的一代人一次的机会。小组讨论集中在沟通的各个方面,包括与决策者沟通时的挑战和策略,理解科学家、记者和公众之间沟通的细微差别,以及围绕数据可视化和信息图表的一些伦理问题。小组成员参与了一场关于价值观是否以及如何在指导、分析和交流证据时发挥作用的激烈辩论。讲习班的教训包括,以色列必须为循证政策创造持久的制度和可持续的环境。必须开发新颖和跨学科的学术课程来培训各个领域的未来决策者,包括公共卫生、公共政策、伦理、通信、社会营销和信息图表。必须在相互尊重和共同致力于创造、综合、实施和传播高质量证据的基础上,培养和加强记者、科学家和政策制定者之间可持续的专业关系,以服务于公众和个人福祉。
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引用次数: 0
Trends and correlated outcomes in population-level prescription opioid and transdermal fentanyl use in Israel. 以色列人口水平处方阿片类药物和透皮芬太尼使用的趋势和相关结果
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2023-03-20 DOI: 10.1186/s13584-023-00558-9
Barak Shapira, Ronny Berkovitz, Ziona Haklai, Nehama Goldberger, Irena Lipshitz, Paola Rosca

Background: In the last twenty years, there was a documented increase in prescription opioid procurement in Israel. However, there is still little evidence of the association between opioid procurement rates, health service utilisation in secondary care, and enrollment rates to substance use disorder treatment programmes. In this study, we show trends in the reports of opioid-related hospitalisations, emergency department visits, enrollment to community-based outpatient treatment for Prescription Opioid Use Disorder and opioid-related mortality rates. Additionally, we examine potential correlations between these health service utilisation rates and prescription opioid procurement rates at the population level, with a focus on transdermal fentanyl.

Methods: A longitudinal study at the population level. We used seven-year data on indicators of opioid-related morbidity, prescription opioid procurement data for 2015-2021, and six-year opioid-related mortality data for 2015-2020. We measure the correlation between procurement rates of prescription opioids in Oral Morphine Equivalent per capita, and aggregated rates obtained from hospital administrative data for hospitalisations, emergency department visits, and patient enrolment in specialised prescription opioid use disorder outpatient treatment in the community setting.

Results: Between 2015 and 2021, procurement rates in primary care per capita for all prescription opioids increased by 85%, while rates of transdermal fentanyl procurement increased by 162%. We found a significant positive correlation at the population level, between annual opioid procurement rates, and rates per population of opioid-related visits to emergency departments (r = 0.96, p value < 0.01, [CI 0.74-0.99]), as well as a positive correlation with the rates per population of patient enrolment in specialised prescription opioid use disorder outpatient treatment (r = 0.93, p value = 0.02, [CI 0.58-0.99]). Opioid-related mortality peaked in 2019 at 0.31 deaths per 100,000 but decreased to 0.20 deaths per 100,000 in 2020.

Conclusion: Data shows that all-opioid and transdermal fentanyl procurement has increased yearly between 2015 and 2021. This increase is positively correlated with a growing demand for community-based Prescription Opioid Use Disorder outpatient treatment. Efforts to reduce opioid-related morbidity may require effective approaches toward appropriate prescribing, monitoring, and further increasing access to prescription opioid outpatient treatment.

背景:在过去的二十年中,以色列的处方阿片类药物采购有所增加。然而,仍然很少有证据表明阿片类药物采购率、二级保健中的卫生服务利用率和药物使用障碍治疗方案的入学率之间存在关联。在本研究中,我们展示了阿片类药物相关住院、急诊就诊、处方阿片类药物使用障碍社区门诊治疗登记和阿片类药物相关死亡率报告的趋势。此外,我们在人口水平上研究了这些卫生服务利用率与处方阿片类药物采购率之间的潜在相关性,重点是透皮芬太尼。方法:在人口水平上进行纵向研究。我们使用了阿片类药物相关发病率指标的7年数据、2015-2021年阿片类药物处方采购数据和2015-2020年6年阿片类药物相关死亡率数据。我们测量了口服吗啡当量中处方阿片类药物的人均购买率与从住院、急诊就诊和社区环境中专门处方阿片类药物使用障碍门诊治疗的医院行政数据中获得的总比率之间的相关性。结果:2015年至2021年间,所有处方阿片类药物的人均初级保健采购率增加了85%,而透皮芬太尼采购率增加了162%。我们发现,在人口水平上,阿片类药物的年度采购率与阿片类药物相关的急诊就诊率之间存在显著的正相关(r = 0.96, p值)。结论:数据显示,2015年至2021年间,全阿片类药物和透皮芬太尼的采购量逐年增加。这一增长与社区处方阿片类药物使用障碍门诊治疗需求的增长呈正相关。努力减少阿片类药物相关的发病率可能需要有效的方法,以适当的处方,监测,并进一步增加获得处方阿片类药物门诊治疗。
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引用次数: 2
When policy meets reality: the new 18-hour on-call shift policy and the Israeli anesthesia workforce crisis. 当政策遇到现实:新的18小时随叫随到轮班政策和以色列麻醉劳动力危机。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2023-03-02 DOI: 10.1186/s13584-023-00556-x
Ariel Wimpfheimer, Charles Weissman, Shai Fein, Yehuda Ginosar

Background: The Israeli physician workforce faces multiple challenges. These include planned policies reducing physician on-call from 26 to 18 h and, from 2026, allowing only graduates of Ministry of Health approved foreign medical schools to take the Israeli licensing examination and an ongoing physician shortage (2019: Israel had 3.19 physicians/1000 persons vs. OECD average of 3.49 physicians/1000 persons). This study examines the potential impact of these planned policies on the Israeli anesthesiology workforce.

Methods: Surveys conducted among 34 public and private Israeli hospital anesthesiology department chairs collected data on their department's number of weekday on-call anesthesiologists and current shortage of anesthesiologists. A subsequent survey collected data on each anesthesiologist in the workforce, including the country where they studied medicine.

Results: Each weekday night there were 114 on-call anesthesiologists; 72 residents and 42 attendings. Using productive work coefficients, this translates to 104 resident and 51 attending anesthesiologists. Furthermore, 21 departments had existing anesthesia workforce shortages totaling 110 anesthesiologists. There were 873 anesthesiologists from non-OECD countries whose medical schools are not accredited by the World Federation for Medical Education, of whom 332 were residents (61.9% of residents). Only 20.1% of anesthesiology residents were Israeli medical school graduates.

Conclusions: Descriptive survey data assessed the immediate and long-term consequences for the healthcare system and anesthesiology workforce of two new Health Ministry policies. Implementing the 18-h policy will immediately remove from the daytime workforce 155 anesthesiologists and who will be unavailable to staff elective surgery operating rooms. This will compound the current national shortage of 110 anesthesiologists. It is unclear how to replace this shortfall since there are no surplus Israeli physicians and very few Israeli graduates choose anesthesiology as a specialty. This situation will be exacerbated after 2026 when graduates of certain foreign medical schools will be unable to enter the medical workforce, further reducing the pool of potential anesthesiology residents. Both policies were promulgated without adequate operational and budgetary planning or fiscal or workforce resources; implementation of the 18-h on-call policy has already been postponed. Therefore, new or updated policies must be accompanied by specific operational plans, budgetary allocations and funds for additional workforce.

背景:以色列医生队伍面临多重挑战。其中包括计划中的政策,将医生随叫随到的时间从26小时减少到18小时,从2026年起,只允许卫生部批准的外国医学院的毕业生参加以色列执照考试,以及医生持续短缺(2019年:以色列有3.19名医生/1000人,而经合组织平均为3.49名医生/1000人)。本研究考察了这些计划政策对以色列麻醉学劳动力的潜在影响。方法:对以色列34家公立和私立医院麻醉科主任进行调查,收集其部门工作日随叫随到的麻醉师数量和当前麻醉师短缺的数据。随后的一项调查收集了劳动力中每个麻醉师的数据,包括他们学习医学的国家。结果:每个工作日晚上有114名值班麻醉医师;72名住院医生和42名主治医生。使用生产性工作系数,这意味着104名住院麻醉师和51名主治麻醉师。此外,21个科室存在麻醉人员短缺,共计110名麻醉医师。来自非经合组织国家的麻醉医师有873名,他们的医学院没有获得世界医学教育联合会的认可,其中332名是住院医师(占住院医师的61.9%)。只有20.1%的麻醉科住院医生是以色列医学院毕业生。结论:描述性调查数据评估了两项卫生部新政策对医疗保健系统和麻醉学工作人员的直接和长期影响。实施18小时政策将立即从日间工作队伍中撤出155名麻醉师,这些麻醉师将无法在工作人员选择的手术手术室工作。这将加剧目前全国110名麻醉师的短缺。目前尚不清楚如何弥补这一缺口,因为以色列没有多余的医生,而且很少有以色列毕业生选择麻醉学作为专业。2026年以后,某些外国医学院的毕业生将无法进入医疗队伍,这种情况将进一步恶化,从而进一步减少潜在的麻醉科住院医师人数。这两项政策都是在没有充分的业务和预算规划或财政或人力资源的情况下颁布的;18小时随叫随到政策的实施已经被推迟。因此,新的或更新的政策必须伴随着具体的业务计划、预算拨款和额外劳动力的资金。
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引用次数: 1
期刊
Israel Journal of Health Policy Research
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