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The Israeli Trauma system during wartime - policy and management. 以色列战时创伤系统--政策与管理。
IF 3.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2024-07-22 DOI: 10.1186/s13584-024-00623-x
Dorit Nitzan, Joseph Mendlovic, Nachman Ash

On October 7, 2023, Hamas terrorists attacked people in their homes, fields, and at a music festival in Israeli communities near the border with Gaza. More than 1,145 men, women, and children were killed, about 1,800 wounded were evacuated to hospitals in the country, and 253 infants, children, women, elderly, and men were abducted. This mass casualty incident (MCI) was the start of a war that is still ongoing. The Israeli medical system, which faced an overwhelming first 24 h, continues to take care of casualties, including those who are injured by missiles that target Israeli residential areas.Israel has a well-established trauma system, and as a result of the experience gained in this war, the system merited review. This was the topic of a meeting of leaders of the Israeli healthcare system, and it forms the basis of this report. The meeting and report provide a platform for presenting the trauma system management during the war, highlighting the strengths of the system as well as its challenges and lessons learned. The participants also brainstormed and discussed possibilities for future improvements.

2023 年 10 月 7 日,哈马斯恐怖分子在以色列与加沙边界附近社区的居民家中、田野和音乐节上发动袭击。超过 1 145 名男子、妇女和儿童丧生,约 1 800 名伤员被送往国内医院,253 名婴儿、儿童、妇女、老人和男子被绑架。这场大规模伤亡事件(MCI)是一场仍在持续的战争的开端。以色列医疗系统在最初的 24 小时内面临着巨大的压力,但仍在继续救治伤员,包括那些被以以色列居民区为目标的导弹炸伤的伤员。以色列有一个完善的创伤系统,由于在这场战争中积累了经验,该系统值得重新审视。这是以色列医疗系统领导人会议的主题,也是本报告的基础。会议和报告为介绍战争期间的创伤系统管理提供了一个平台,突出了该系统的优势及其面临的挑战和吸取的经验教训。与会者还集思广益,讨论了未来改进的可能性。
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引用次数: 0
Frailty and its association with long-term mortality among community-dwelling older adults aged 75 years and over. 体弱及其与 75 岁及以上居住在社区的老年人长期死亡率的关系。
IF 3.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2024-07-16 DOI: 10.1186/s13584-024-00614-y
Maor Lewis, Anthony Heymann, Galia Zacay, Dan Justo

Background: Frailty, a significant risk factor for adverse outcomes and mortality, poses an emerging challenge with profound implications for public health and clinical practice. The measurement of frailty offers potential enhancements in healthcare services for older adults. The prevalence of frailty and its association with long-term mortality in a nationwide, unselected population of community-dwelling older adults, particularly those aged 75 and over, has not been previously studied on a large scale in Israel.

Methods: A retrospective cohort study was conducted at Meuhedet Health Maintenance Organization, Israel's third largest healthcare service provider, serving 1,276,000 people (13.8% of Israelis). The prevalence of frailty and its association with all-cause mortality were studied among older adults aged 75 years and over who were followed for 2-8 years. Frailty, defined by the cumulative deficit method, utilized clinical data from the preceding 10-year period, comprising 28 chronic diseases and age-related health deficits.

Results: The cohort included 43,737 older adults, with a median age of 77 years (IQR 75-82 years); among them, 19,300 (44.1%) were males. Overall, 19,396 (44.3%) older adults were frail: 12,260 (28.0%) mildly frail, 5,533 (12.7%) moderately frail and 1,603 (3.7%) severely frail. During the follow-up period 15,064 (34.4%) older adults died: 4,782 (39.0%) mildly frail, 3,016 (54.5%) moderately frail and 1,080 (67.4%) severely frail. Cox regression analysis demonstrated that mortality was associated with severe frailty (HR 2.63, 95%CI 2.45-2.80), moderate frailty (HR 2.05, 95%CI 1.96-2.14), and mild frailty (HR 1.45, 95%CI 1.39-1.51), independent of age, gender, and population sector. Among patients aged 90 years and over, no significant differences in cumulative survival were found between those with moderate and severe frailty (p = 0.408).

Conclusions: Frailty is prevalent among community-dwelling Israeli older adults aged 75 years and over, and it is associated with long-term mortality. Considering its association with long-term mortality across frailty levels until the age of 90, early identification and intervention for frailty are recommended within this population. Policymakers should consider the use of the cumulative deficit method for evaluating frailty at both the population health and clinical levels.

背景:虚弱是导致不良后果和死亡率的一个重要风险因素,是一个新出现的挑战,对公共卫生和临床实践有着深远的影响。对虚弱程度的测量有可能改善老年人的医疗保健服务。以色列以前从未大规模研究过全国范围内未经选择的社区老年人,尤其是 75 岁及以上老年人的体弱患病率及其与长期死亡率的关系:方法:在以色列第三大医疗保健服务提供商 Meuhedet 健康维护组织开展了一项回顾性队列研究,该组织为 127.6 万人(占以色列人的 13.8%)提供服务。研究人员对 75 岁及以上的老年人进行了为期 2 至 8 年的跟踪调查,研究了虚弱的普遍性及其与全因死亡率的关系。虚弱的定义采用累积缺陷法,利用了前 10 年的临床数据,包括 28 种慢性疾病和与年龄相关的健康缺陷:组群包括 43737 名老年人,中位年龄为 77 岁(IQR 75-82 岁);其中 19300 名(44.1%)为男性。总体而言,19,396 名(44.3%)老年人体弱:12,260 名(28.0%)轻度体弱,5,533 名(12.7%)中度体弱,1,603 名(3.7%)重度体弱。在随访期间,15,064 名(34.4%)老年人死亡:4,782 名(39.0%)轻度体弱,3,016 名(54.5%)中度体弱,1,080 名(67.4%)重度体弱。Cox 回归分析表明,死亡率与严重虚弱(HR 2.63,95%CI 2.45-2.80)、中度虚弱(HR 2.05,95%CI 1.96-2.14)和轻度虚弱(HR 1.45,95%CI 1.39-1.51)有关,与年龄、性别和人口部门无关。在90岁及以上的患者中,中度和重度虚弱患者的累积存活率没有明显差异(P = 0.408):在 75 岁及以上居住在社区的以色列老年人中,体弱现象十分普遍,而且与长期死亡率有关。考虑到在 90 岁之前,不同程度的虚弱都与长期死亡率有关,因此建议对这一人群进行早期识别和干预。政策制定者应考虑在人群健康和临床层面使用累积亏损法评估虚弱程度。
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引用次数: 0
Factors affecting decisions of an HMO Drug Exemptions Committee on individual patient requests for coverage of non-formulary drugs. 影响 HMO 药物豁免委员会就患者个人申请承保非处方药的决定的因素。
IF 3.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2024-07-15 DOI: 10.1186/s13584-024-00617-9
Yael Topol, Lior Weiss, Yossi Lomnicky, Inbal Yifrach-Damari, Noa Markovits, Ronen Loebstein, Itai Gueta

Background: In Israel, coverage of health needs is delivered by four health maintenance organizations (HMOs), which are budgeted by the government according to the recommendations of the National Drug Formulary (NDF) Committee. For medications not listed in the NDF, individuals may request to cover the costs by the HMO Exemptions Committee (DEC). The objectives of the current study, a first of its kind, are to document the DEC decision process, to identify its components and to determine the decisions' clinical outcome.

Methods: This retrospective cohort study included all members (≥ age 18) of the Maccabi Healthcare Service (MHS) who submitted a request to the DEC between June 2017 and December 2018. Collected data include patient demographics, clinical information and components of the decision process. Decision success (i.e., clinical outcome correlated with DEC decision) was determined by clinical outcome over at least one-year follow-up.

Results: A total of 335 requests were included. Strong evidence and rare disease were positively associated with approvals, while the availability of alternative treatments and costs were negatively associated. The majority of decisions (75%) met predicted clinical outcomes. Only estimated costs were found to be associated with decision success.

Conclusions: Factors that reduce the potential costs of a requested drug are significantly associated with higher odds for drug approval, but only when the evidence supports potential benefit.

背景:在以色列,保健需求由四个保健组织(HMO)提供,政府根据国家药物表(NDF)委员会的建议为其编制预算。对于未列入 NDF 的药物,个人可向 HMO 豁免委员会(DEC)申请支付费用。本研究是同类研究中的第一项,其目的是记录 DEC 的决策过程,确定其组成部分,并确定决策的临床结果:这项回顾性队列研究包括马卡比医疗服务机构(MHS)在 2017 年 6 月至 2018 年 12 月期间向 DEC 提交申请的所有成员(≥ 18 岁)。收集的数据包括患者人口统计学、临床信息和决策过程的组成部分。决策成功率(即与 DEC 决策相关的临床结果)根据至少一年随访的临床结果确定:结果:共纳入 335 份申请。强有力的证据和罕见疾病与批准呈正相关,而替代疗法的可用性和成本呈负相关。大多数决定(75%)符合预测的临床结果。只有估计成本与决策成功率相关:结论:降低申请药物潜在成本的因素与更高的药物批准几率显著相关,但只有在证据支持潜在益处的情况下。
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引用次数: 0
The importance of vision care for displaced populations: lessons from Israeli evacuees. 为流离失所者提供视力保健的重要性:以色列疏散人员的经验教训。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2024-06-06 DOI: 10.1186/s13584-024-00615-x
Hadas Ben-Eli, Itay Chowers, Ariela Gordon-Shaag

Background: This study explores vision care priorities and coping mechanisms for Israeli evacuees and following the October 7th, 2023, attack by Hamas, which displaced 150,000 individuals, with about 15,000 being evacuated to the Dead Sea area. Faced with minimal health care infrastructure in the Dead Sea area and often lacking personal belongings, including eyeglasses and ocular medicine, these evacuees confronted significant vision care challenges. This context sets the stage for investigating the emergency vision care needs and solutions for populations affected by conflict and displacement.

Methods: In response to this crisis, a consortium led by Hadassah Academic College's Department of Optometry and the Dept. of Ophthalmology at Hadassah Medical Center established ophthalmic clinics in the Dead Sea region. These clinics offered comprehensive vision care services, including refractive and vision examinations, ophthalmological assessments, ocular imaging, and provision of free glasses. The setup included multiple stations for different vision tests, staffed by an interdisciplinary team of professionals. The study analyzes the effectiveness of these clinics, patient flow challenges, and the psychological impact of vision care in a crisis setting.

Results: Approximately 800 evacuees received examinations, with around 700 pairs of glasses distributed. Notable cases included emergency referrals for serious conditions and instances where glasses served as psychological support. The operation highlighted the necessity of vision care during crises and its potential psychological and social implications. The clinics successfully provided immediate vision care, but challenges in patient flow and insufficient electronic medical record integration were noted. The experience underscores the importance of prepared eye care interventions in crises. Recommendations for health policy decision-makers include establishing a national emergency vision care network, developing standardized treatment protocols, training local health workers, and raising public awareness about eye health in emergencies.

Conclusions: The consortium's effort in providing urgent vision care to evacuees from the Hamas attack on Israel demonstrates the critical role of rapid, organized eye care in crisis situations. Vision care, along with hearing and mobility, is often overlooked during evacuations but is vital for the well-being and survival of evacuees, especially under trying circumstances. This project serves as a model for future humanitarian interventions, emphasizing the importance of addressing overlooked healthcare issues once the immediate crisis has passed, and the need for strategic planning in health care policy for similar emergency scenarios.

背景:2023 年 10 月 7 日,哈马斯发动袭击,造成 15 万人流离失所,其中约 1.5 万人被疏散到死海地区。面对死海地区极少的医疗基础设施,以及通常缺乏包括眼镜和眼科药物在内的个人物品,这些撤离者面临着巨大的视力保健挑战。这一背景为研究受冲突和流离失所影响人群的紧急视力保健需求和解决方案提供了基础:为了应对这场危机,哈大沙学术学院验光系和哈大沙医疗中心眼科部领导的一个联合体在死海地区建立了眼科诊所。这些诊所提供全面的视力保健服务,包括屈光和视力检查、眼科评估、眼部成像和提供免费眼镜。诊所的设置包括多个不同视力检测站,由跨学科的专业团队提供服务。研究分析了这些诊所的有效性、病人流量挑战以及危机环境下视力保健的心理影响:结果:约有 800 名疏散人员接受了检查,并分发了约 700 副眼镜。值得注意的案例包括严重疾病的紧急转诊和眼镜作为心理支持的情况。这次行动强调了危机期间视力保健的必要性及其潜在的心理和社会影响。诊所成功地提供了即时的视力保健服务,但也注意到在病人流动和电子病历整合方面存在的挑战。这次经验强调了在危机中进行有准备的视力保健干预的重要性。对卫生政策决策者的建议包括建立全国紧急视力保健网络、制定标准化治疗方案、培训当地卫生工作者以及提高公众对紧急情况下眼睛健康的认识:联合体为从哈马斯袭击以色列事件中撤离的人员提供紧急视力保健服务的努力表明,快速、有组织的眼保健服务在危机情况下发挥着至关重要的作用。视力保健与听力和行动能力一样,在撤离过程中经常被忽视,但对于撤离人员的福祉和生存却至关重要,尤其是在艰难的情况下。该项目为未来的人道主义干预行动树立了典范,强调了在紧急危机过去后解决被忽视的医疗保健问题的重要性,以及为类似紧急情况制定医疗保健政策战略规划的必要性。
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引用次数: 0
Timely care for age-related macular degeneration: a qualitative study among retina specialists in Israel. 老年黄斑变性的及时治疗:对以色列视网膜专家的定性研究。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2024-06-04 DOI: 10.1186/s13584-024-00616-w
Vicki Myers, Osnat Luxenburg, Rachel Wilf-Miron, Hani Levkovitch Verbin

Background: Age-related macular degeneration (AMD) affects quality of life and independence, and its incidence and prevalence are increasing due to ageing of the population. Access to effective timely treatment can improve vision and reduce incidence of blindness. This study aimed to explore the perspectives of ophthalmologists in the Israeli public healthcare system regarding timely treatment of AMD patients.

Methods: Qualitative semi-structured interviews were conducted in 2020-2021 with 22 senior ophthalmologists, from 10 general hospitals and from two HMOs, representing different geographic regions. All interviewees specialize in retinal diseases and work with AMD patients. Interviews discussed patient pathways involved in the diagnosis and treatment of AMD, access to care, and obstacles to timely care. Thematic analysis was conducted.

Results: Based on the interviews, we describe the usual referral and treatment pathways. Themes included regional disparities, long wait times in some areas, a lack of retina specialists, differences in referral pathways, inappropriate use of emergency department to obtain timely treatment, and second-line treatment not fully covered by insurance, most affecting the weakest segments of the population.

Conclusions: Loss of vision incurs high health and societal costs. In the context of insufficient medical manpower in Israel, the healthcare system will need to assess future resources to cope with accumulating burden of AMD cases over time in an ageing population. Precise referral information, and simultaneous referral to imaging and retinal clinics, may minimize delays in treatment. Awareness of AMD symptoms and the importance of early intervention could be highlighted by campaigns, particularly among high-risk groups.

Highlights: • Interviews with hospital-based and community ophthalmologists showed regional disparities in AMD treatment, with long wait times and a lack of retina specialists in some areas. • Differences in referral pathways, inappropriate use of emergency department to obtain timely treatment, and second line treatment not fully covered by insurance were highlighted. • The healthcare system will need to assess future resources to cope with accumulating burden of AMD cases over time in an ageing population • Precise referral information, and simultaneous referral to imaging and retinal clinics, may minimize delays in treatment. • Awareness of AMD symptoms and the importance of early intervention should be emphasized in high-risk groups.

背景:年龄相关性黄斑变性(AMD)影响生活质量和独立性,其发病率和流行率因人口老龄化而不断上升。及时获得有效治疗可以改善视力,降低失明率。本研究旨在探讨以色列公共医疗系统中的眼科医生对及时治疗 AMD 患者的看法:2020-2021 年,我们对来自 10 家综合医院和两家 HMO(代表不同地区)的 22 名资深眼科医生进行了半结构式定性访谈。所有受访者均擅长视网膜疾病,并为 AMD 患者提供服务。访谈讨论了诊断和治疗老年性视网膜病变所涉及的患者路径、获得护理的途径以及及时护理的障碍。我们进行了专题分析:根据访谈,我们描述了通常的转诊和治疗途径。主题包括地区差异、某些地区等待时间过长、缺乏视网膜专科医生、转诊途径存在差异、为获得及时治疗而不适当地使用急诊科、二线治疗未完全纳入保险范围等,这些问题对人口中最弱势的群体影响最大:结论:视力丧失会造成高昂的医疗和社会成本。在以色列医护人员不足的情况下,医疗系统需要评估未来的资源,以应对随着时间推移人口老龄化而不断增加的 AMD 病例负担。准确的转诊信息以及同时转诊至影像和视网膜诊所可最大限度地减少治疗延误。可以通过宣传活动,特别是针对高危人群的宣传活动,提高人们对老年性视网膜病变症状和早期干预重要性的认识:- 对医院和社区眼科医生的访谈显示,AMD 的治疗存在地区差异,有些地区的等待时间很长,而且缺乏视网膜专科医生。- 转诊途径的差异、为获得及时治疗而不适当地使用急诊科以及二线治疗未完全纳入保险范围等问题也得到了强调。- 医疗系统需要评估未来的资源,以应对随着人口老龄化而不断累积的老年性视网膜病变病例--准确的转诊信息以及同时转诊至影像科和视网膜科,可最大限度地减少治疗延误。- 应在高危人群中强调对老年性视网膜病变症状的认识和早期干预的重要性。
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引用次数: 0
Demographic and injury trends for car crash casualties hospitalized in Level I Trauma centers over two decades: data from the National Trauma Registry. 二十年来在一级创伤中心住院的车祸伤员的人口统计和受伤趋势:来自国家创伤登记处的数据。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2024-05-29 DOI: 10.1186/s13584-024-00613-z
Sharon Goldman, Irit Cohen-Manheim, Irina Radomislensky, Bella Savitsky, Moran Bodas

Background: During the past two decades, there have been many changes in automotive and medical technologies, road infrastructure, trauma systems, and demographic changes which may have influenced injury outcomes. The aim of this study was to examine injury trends among traffic casualties, specifically private car occupants, hospitalized in Level I Trauma Centers (TC).

Methods: A retrospective cohort study was performed based on data from the Israel National Trauma Registry. The data included occupants of private cars hospitalized in all six Level I TC due to a traffic collision related injury between January 1, 1998 and December 31, 2019. Demographic, injury and hospitalization characteristics and in-hospital mortality were analyzed. Chi-squared (X2) test, multivariable logistic regression models and Spearman's rank correlation were used to analyze injury data and trends.

Results: During the study period, 21,173 private car occupants (14,078 drivers, 4,527 front passengers, and 2,568 rear passengers) were hospitalized due to a traffic crash. The percentage of females hospitalized due to a car crash increased from 37.7% in 1998 to 53.7% in 2019. Over a twofold increase in hospitalizations among older adult drivers (ages 65+) was observed, from 6.5% in 1998 to 15.7% in 2018 and 12.6% in 2019. While no increase was observed for severe traumatic brain injury, a statistically significant increase in severe abdominal and thoracic injuries was observed among the non-Jewish population along with a constant decrease in in-hospital mortality.

Conclusions: This study provides interesting findings regarding injury and demographic trends among car occupants during the past two decades. Mortality among private car occupant casualties decreased during the study period, however an increase in serious abdominal and thoracic injuries was identified. The results should be used to design and implement policies and interventions for reducing injury and disability among car occupants.

背景:在过去的二十年中,汽车和医疗技术、道路基础设施、创伤系统以及人口结构的变化都发生了许多变化,这些变化可能会对伤害结果产生影响。本研究旨在探讨在一级创伤中心(TC)住院治疗的交通事故伤员(尤其是私家车乘员)的受伤趋势:方法:根据以色列国家创伤登记处的数据进行了一项回顾性队列研究。数据包括 1998 年 1 月 1 日至 2019 年 12 月 31 日期间因交通碰撞相关伤害而在所有六个一级创伤中心住院治疗的私家车乘员。对人口统计学、受伤和住院特征以及住院死亡率进行了分析。采用卡方检验(X2)、多变量逻辑回归模型和斯皮尔曼等级相关性分析受伤数据和趋势:在研究期间,21,173 名私家车乘客(14,078 名司机、4,527 名前排乘客和 2,568 名后排乘客)因交通事故住院。因车祸住院的女性比例从 1998 年的 37.7% 上升到 2019 年的 53.7%。老年驾驶员(65 岁以上)的住院率增加了两倍多,从 1998 年的 6.5% 增加到 2018 年的 15.7% 和 2019 年的 12.6%。虽然没有观察到严重脑外伤的增加,但在非犹太人口中观察到严重腹部和胸部损伤有统计学意义的显著增加,同时院内死亡率持续下降:这项研究提供了有关过去 20 年间汽车乘客受伤情况和人口趋势的有趣发现。在研究期间,私家车乘员的死亡率有所下降,但发现腹部和胸部严重受伤的人数有所增加。研究结果应用于设计和实施减少汽车乘客受伤和残疾的政策和干预措施。
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引用次数: 0
Correction to: The Hamas massacre of Oct 7, 2023, and its aftermath, medical crimes, and the Lancet commission report on medicine, Nazism, and the Holocaust. 更正:2023 年 10 月 7 日哈马斯大屠杀及其后果、医疗犯罪以及柳叶刀委员会关于医学、纳粹主义和大屠杀的报告。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2024-05-07 DOI: 10.1186/s13584-024-00610-2
Shmuel P Reis, Hedy S Wald
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引用次数: 0
Exploring pre-MRI imaging tests: patient survey reveals potential implications for healthcare efficiency in Israel. 探索核磁共振成像前的成像检查:患者调查揭示了对以色列医疗效率的潜在影响。
IF 3.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2024-04-01 DOI: 10.1186/s13584-024-00593-0
Arielle Kaim, Clara Singer, Lucia Bergovoy-Yellin, Osnat Luxenburg, Sharona Vaknin, Noga Boldor, Rachel Wilf-Miron, Vicki Myers

Background: Medical imaging tests are vital in healthcare but can be costly, impacting national health expenditures. Magnetic resonance imaging (MRI) is a crucial diagnostic tool for assessing medical conditions. However, the rising demand for MRI scans has frequently strained available resources. This study aimed to estimate the prevalence of different imaging tests in individuals who eventually had an MRI, in the Israeli public health system.

Methods: An online survey of patient experience of scheduling an MRI was conducted in January-February 2023, among 557 Israeli adults, representing all four health maintenance organizations (HMOs). All participants had undergone an MRI in the public health system within the past year.

Results: Results showed that 60% of participants underwent other imaging tests before their MRI scan. Of those, computed tomography (CT) scans (43%), X-rays (39%), and ultrasounds (32%) were the most common additional imaging procedures. In addition, of the 60% of participants, 23% had undergone more than one prior imaging examination.

Conclusions: These findings highlight the high prevalence of preliminary imaging tests prior to MRI, with many patients undergoing multiple tests for the same problem. The health system may need to evaluate whether current clinical guidelines defining the use of various imaging tests are cost-effective.

背景:医学影像检查在医疗保健中至关重要,但成本高昂,影响国民健康支出。磁共振成像(MRI)是评估医疗状况的重要诊断工具。然而,核磁共振成像扫描需求的不断增长常常使可用资源捉襟见肘。本研究旨在估算以色列公共卫生系统中最终接受核磁共振成像检查的患者接受不同成像检查的比例:方法:2023 年 1 月至 2 月,我们对 557 名以色列成年人进行了核磁共振成像检查预约体验在线调查,调查对象包括所有四家健康维护组织 (HMO)。所有参与者在过去一年内均在公共医疗系统接受过核磁共振成像检查:结果显示,60%的参与者在接受核磁共振成像扫描前接受了其他成像检查。其中,计算机断层扫描(CT)(43%)、X 光(39%)和超声波(32%)是最常见的附加成像程序。此外,在 60% 的参与者中,23% 的人之前接受过一次以上的成像检查:这些研究结果突显了在进行核磁共振成像之前进行初步成像检查的普遍性,许多患者因同一问题接受了多次检查。医疗系统可能需要评估目前界定使用各种成像检查的临床指南是否具有成本效益。
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引用次数: 0
Drug shortages in Israel, revisited: a bitter pill to swallow. 以色列药品短缺问题再探:难以下咽的苦果。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2024-03-18 DOI: 10.1186/s13584-024-00600-4
Eyal Schwartzberg, Eli Marom, Alla Vishkautzan, Einat Gorelik, Segev Shani

Background: In 2017, we published an article addressing drug shortages (DS) in Israel, exploring regulatory perspectives, challenges, and potential solutions. Since then, DS remain a significant concern for patients, healthcare providers, and policymakers globally. In this updated article, we revisit the topic, providing new insights, data, and analysis on the current DS landscape in Israel, efforts to mitigate them, and propose strategies to combat this escalating issue.

Methods: We conducted a comprehensive search of the Israeli Ministry of Health (MOH) DS database, spanning from 2014 to the present. We extracted DS numbers and their reasons. Further searches on the Israeli MOH website, pharmaceutical division archives, and the internet yielded official MOH publications and correspondence regarding regulatory responses to DS from 2017 onwards. Additionally, two specific cases of DS were examined to analyze their handling. Recent activities and publications from the Israeli MOH aimed at reducing DS were also reviewed.

Results: Between 2014 and 2022, DS surged 2.66-fold. Total DS were 3228; 672 due to commercial reasons, and 2556 to operational reasons (20.5% and 79.5% respectively). The average duration of intermittent DS increased 1.56-fold, from 85 to 133 days. Manufacturers informed the MOH 22 days prior to actual shortage on average. Analyzing 2022's DS (640) by ATC groups, prominent categories included nervous system drugs (18%), drugs acting on the alimentary tract and metabolism (14%), and dermatologicals (11%). Operational DS in 2022 (n = 564) were primarily due to stock delivery delays (38%), stock over-utilization (12%), and raw material shortages (9%). Sixteen official MOH publications on DS were identified from 2017 onwards. Moreover, two high-impact DS case studies were examined.

Conclusion: Despite routine monitoring by the Israeli MOH and updating the DS policy throughout this period, DS persist, intensifying annually and posing serious health risks. This trend mirrors international patterns, affecting countries globally. In Israel's uniquely structured healthcare system, with its swift stakeholder cooperation and implementation capabilities, more effective DS management is conceivable. We propose ten universally applicable rules to address DS challenges.

背景:2017 年,我们发表了一篇关于以色列药物短缺(DS)的文章,探讨了监管视角、挑战和潜在解决方案。从那时起,药物短缺仍然是全球患者、医疗服务提供者和政策制定者关注的一个重要问题。在这篇更新的文章中,我们重新审视了这一话题,提供了有关以色列目前DS状况的新见解、数据和分析,以及为缓解DS所做的努力,并提出了应对这一不断升级的问题的策略:我们对以色列卫生部(MOH)的 DS 数据库进行了全面搜索,时间跨度从 2014 年至今。我们提取了 DS 数量及其原因。通过进一步搜索以色列卫生部网站、制药部门档案和互联网,我们获得了卫生部自 2017 年以来有关 DS 监管对策的官方出版物和信函。此外,还研究了两个具体的 DS 案例,以分析其处理情况。此外,还审查了以色列卫生部近期旨在减少 DS 的活动和出版物:结果:2014 年至 2022 年间,DS 激增了 2.66 倍。DS 总数为 3228 个;其中 672 个是由于商业原因,2556 个是由于操作原因(分别占 20.5%和 79.5%)。间歇性 DS 的平均持续时间增加了 1.56 倍,从 85 天增加到 133 天。制造商平均在实际短缺前 22 天通知卫生部。按ATC类别分析2022年的DS(640种),主要类别包括神经系统药物(18%)、作用于消化道和新陈代谢的药物(14%)以及皮肤病药物(11%)。2022 年运行中的 DS(564 人)主要是由于库存交付延迟(38%)、库存过度使用(12%)和原材料短缺(9%)造成的。自 2017 年起,共发现 16 份有关 DS 的卫生部官方出版物。此外,还研究了两个影响较大的 DS 案例:尽管以色列卫生部在此期间进行了例行监测并更新了 DS 政策,但 DS 依然存在,并且每年都在加剧,造成了严重的健康风险。这一趋势反映了国际模式,影响着全球各国。以色列的医疗保健系统结构独特,利益相关者合作迅速,执行能力强,因此可以对 DS 进行更有效的管理。我们提出了十条普遍适用的规则,以应对 DS 挑战。
{"title":"Drug shortages in Israel, revisited: a bitter pill to swallow.","authors":"Eyal Schwartzberg, Eli Marom, Alla Vishkautzan, Einat Gorelik, Segev Shani","doi":"10.1186/s13584-024-00600-4","DOIUrl":"10.1186/s13584-024-00600-4","url":null,"abstract":"<p><strong>Background: </strong>In 2017, we published an article addressing drug shortages (DS) in Israel, exploring regulatory perspectives, challenges, and potential solutions. Since then, DS remain a significant concern for patients, healthcare providers, and policymakers globally. In this updated article, we revisit the topic, providing new insights, data, and analysis on the current DS landscape in Israel, efforts to mitigate them, and propose strategies to combat this escalating issue.</p><p><strong>Methods: </strong>We conducted a comprehensive search of the Israeli Ministry of Health (MOH) DS database, spanning from 2014 to the present. We extracted DS numbers and their reasons. Further searches on the Israeli MOH website, pharmaceutical division archives, and the internet yielded official MOH publications and correspondence regarding regulatory responses to DS from 2017 onwards. Additionally, two specific cases of DS were examined to analyze their handling. Recent activities and publications from the Israeli MOH aimed at reducing DS were also reviewed.</p><p><strong>Results: </strong>Between 2014 and 2022, DS surged 2.66-fold. Total DS were 3228; 672 due to commercial reasons, and 2556 to operational reasons (20.5% and 79.5% respectively). The average duration of intermittent DS increased 1.56-fold, from 85 to 133 days. Manufacturers informed the MOH 22 days prior to actual shortage on average. Analyzing 2022's DS (640) by ATC groups, prominent categories included nervous system drugs (18%), drugs acting on the alimentary tract and metabolism (14%), and dermatologicals (11%). Operational DS in 2022 (n = 564) were primarily due to stock delivery delays (38%), stock over-utilization (12%), and raw material shortages (9%). Sixteen official MOH publications on DS were identified from 2017 onwards. Moreover, two high-impact DS case studies were examined.</p><p><strong>Conclusion: </strong>Despite routine monitoring by the Israeli MOH and updating the DS policy throughout this period, DS persist, intensifying annually and posing serious health risks. This trend mirrors international patterns, affecting countries globally. In Israel's uniquely structured healthcare system, with its swift stakeholder cooperation and implementation capabilities, more effective DS management is conceivable. We propose ten universally applicable rules to address DS challenges.</p>","PeriodicalId":46694,"journal":{"name":"Israel Journal of Health Policy Research","volume":"13 1","pages":"14"},"PeriodicalIF":4.5,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10946123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disclosure following a medical error: lessons learned from a national initiative of workshops with patients, healthcare teams, and executives. 医疗事故发生后的信息披露:从与患者、医疗团队和管理人员举办的全国性研讨会中汲取的经验教训。
IF 4.5 4区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2024-03-11 DOI: 10.1186/s13584-024-00599-8
Adi Finkelstein, Mayer Brezis, Amiad Taub, Dana Arad

Background: Despite the increase in disclosures of medical errors, transparency remains a challenge. Recognized barriers include shame, fear of litigation, disciplinary actions, and loss of patient trust. In 2018, the Israeli Ministry of Health initiated a series of workshops about disclosure of medical errors. The workshops involved medical center executives, healthcare providers, patients, and family members of patients who had previously been harmed by a medical error. This study presents the lessons learned about perceived challenges in disclosure of errors in 15 such workshops.

Methods: Data collection included participant observations in 15 workshops, full audio recordings of all of the workshops, and documentation of detailed field notes. Analysis was performed under thematic analysis guidelines.

Results: We identified four main themes: "Providers agree on the value of disclosure of a medical error to the patient"; "Emotional challenges of disclosure of medical error to patients"; "The medico-legal discourse challenges transparency"; and "Providers and patients call for a change in the culture regarding disclosure of medical errors". Participant observations indicated that the presence of a patient who had experienced a tragedy in another hospital, and who was willing to share it created an intimate atmosphere that enabled an open conversation between parties.

Conclusion: The study shows the moral, human, and educational values of open discourse in a protective setting after the occurrence of a medical error. We believe that workshops like these may help foster a culture of institutional disclosure following medical errors. We recommend that the Ministry of Health extend such workshops to all healthcare facilities, establish guidelines and mandate training for skills in disclosure for all providers.

背景:尽管披露医疗事故的情况越来越多,但透明度仍然是一项挑战。公认的障碍包括羞耻感、对诉讼的恐惧、纪律处分以及失去患者的信任。2018 年,以色列卫生部发起了一系列关于披露医疗事故的研讨会。参与研讨会的有医疗中心管理人员、医疗服务提供者、患者以及曾受到医疗事故伤害的患者家属。本研究介绍了在 15 次此类研讨会上所汲取的有关披露医疗事故所面临挑战的经验教训:数据收集包括 15 场研讨会的参与者观察、所有研讨会的完整录音以及详细的现场记录。结果:我们确定了四个主题:"在工作坊中,我们发现了哪些挑战?我们确定了四大主题:"医疗服务提供者认同向患者披露医疗事故的价值";"向患者披露医疗事故的情感挑战";"医学法律话语挑战透明度";以及 "医疗服务提供者和患者呼吁改变披露医疗事故的文化"。参与者的观察表明,一位曾在另一家医院经历过悲剧并愿意分享的患者的存在营造了一种亲密的氛围,使双方能够进行坦诚的对话:这项研究表明,在医疗事故发生后的保护性环境中进行公开对话具有道德、人文和教育价值。我们相信,类似的研讨会可能有助于培养医疗事故发生后的机构披露文化。我们建议卫生部将此类研讨会推广到所有医疗机构,制定指导方针,并强制要求对所有医疗服务提供者进行披露技能培训。
{"title":"Disclosure following a medical error: lessons learned from a national initiative of workshops with patients, healthcare teams, and executives.","authors":"Adi Finkelstein, Mayer Brezis, Amiad Taub, Dana Arad","doi":"10.1186/s13584-024-00599-8","DOIUrl":"10.1186/s13584-024-00599-8","url":null,"abstract":"<p><strong>Background: </strong>Despite the increase in disclosures of medical errors, transparency remains a challenge. Recognized barriers include shame, fear of litigation, disciplinary actions, and loss of patient trust. In 2018, the Israeli Ministry of Health initiated a series of workshops about disclosure of medical errors. The workshops involved medical center executives, healthcare providers, patients, and family members of patients who had previously been harmed by a medical error. This study presents the lessons learned about perceived challenges in disclosure of errors in 15 such workshops.</p><p><strong>Methods: </strong>Data collection included participant observations in 15 workshops, full audio recordings of all of the workshops, and documentation of detailed field notes. Analysis was performed under thematic analysis guidelines.</p><p><strong>Results: </strong>We identified four main themes: \"Providers agree on the value of disclosure of a medical error to the patient\"; \"Emotional challenges of disclosure of medical error to patients\"; \"The medico-legal discourse challenges transparency\"; and \"Providers and patients call for a change in the culture regarding disclosure of medical errors\". Participant observations indicated that the presence of a patient who had experienced a tragedy in another hospital, and who was willing to share it created an intimate atmosphere that enabled an open conversation between parties.</p><p><strong>Conclusion: </strong>The study shows the moral, human, and educational values of open discourse in a protective setting after the occurrence of a medical error. We believe that workshops like these may help foster a culture of institutional disclosure following medical errors. We recommend that the Ministry of Health extend such workshops to all healthcare facilities, establish guidelines and mandate training for skills in disclosure for all providers.</p>","PeriodicalId":46694,"journal":{"name":"Israel Journal of Health Policy Research","volume":"13 1","pages":"13"},"PeriodicalIF":4.5,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10926562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140094802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Israel Journal of Health Policy Research
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