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Direct bacterioscopic observation of Helicobacter in the oral cavity, stomach and rectum 口腔、胃、直肠幽门螺杆菌的直接细菌学观察
Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2017.3247
V. Kravtsov, Maria Taame, B. Gumilevskiy
Background Bacterial cells of Helicobacter Pylori (HP) are often found in people with chronic gastritis and peptic ulcer disease (PUD). All patients with symptoms are usually screened for HP bacterial cells by different methods of detection. Studies have shown that HP can colonize the stomach and other parts of the gastorointestinal tract such as the oral cavity and rectum. Aims To visualize and evaluate the bacterial cells of Helicobacter Pylori in vivo in the gastric, oral and rectal mucosa using immunocytochemical detection. Methods Studies were carried out on smears from biopsies of the oral cavity, rectum and stomach (ICD-10K29.3) from seventy patients with chronic gastritis for the detection of Helicobacter pylori (HP) using immunocytochemistry. This technique allows detection of both coccoid and spiral forms of HP. Results Our research demonstrated that the stomach was dominated by spiral forms, with coccoid forms being much less common (on average about 5 per cent). There was a quite different distribution of spirals and cocci in the oral cavity and rectum. The oral cavity demonstrated almost exclusively coccoid forms of HP, rarely spiral and HP were detected only in coccoid forms in the rectum. Bacterioscopic investigation of gastrointestinal mucosa carried out via direct immunocytochemical staining clearly shows that HP mucosal colonization occurs in the stomach (typically more than 50 helical cells in a single field of view), and that HP exits the body through the oral cavity and intestinal tract (5–10 cocci forms in 300 fields of view). Results of HP detection in the oral cavity and rectum corresponded with HP detection in the stomach in 80 per cent and 83 per cent of cases, respectively. Conclusion Immunocytochemical observation of HP in the oral cavity, stomach and rectal mucosa suggests that HP bacterial cells enter the gastrointestinal tract as coccoids, colonize stomach mucosa in vegetative spiral form and leave as coccoid forms. Thus, our data from direct bacterioscopy strongly supports the hypothesis that HP infection spreads and contaminates the gastrointestinal tract through its coccoid forms.
背景幽门螺杆菌(HP)细菌细胞常见于慢性胃炎和消化性溃疡(PUD)患者。所有有症状的患者通常通过不同的检测方法筛查HP细菌细胞。研究表明,HP可以在胃和胃肠道的其他部位如口腔和直肠中定植。目的应用免疫细胞化学方法观察胃、口腔和直肠粘膜中幽门螺杆菌的生长情况。方法对70例慢性胃炎患者进行口腔、直肠和胃活检涂片(ICD-10K29.3)免疫细胞化学检测幽门螺杆菌(HP)。这种技术可以检测出球型和螺旋型HP。结果:我们的研究表明,胃以螺旋型为主,球型较少见(平均约5%)。螺旋菌和球菌在口腔和直肠的分布有很大差异。口腔癌几乎全部呈球型HP,很少呈螺旋状,且HP仅在直肠球型中检出。通过直接免疫细胞化学染色对胃肠道粘膜进行的细菌学检查清楚地表明,HP在胃粘膜定植(通常在单个视野内超过50个螺旋细胞),并且HP通过口腔和肠道排出体外(300个视野内形成5-10个球菌)。口腔和直肠HP检测结果与胃HP检测结果相吻合的比例分别为80%和83%。结论口腔、胃和直肠粘膜HP的免疫细胞化学观察表明,HP细菌细胞以球虫形式进入胃肠道,以营养螺旋形式定植胃粘膜,以球虫形式离开。因此,我们直接细菌学检查的数据有力地支持了HP感染通过其球虫形式传播并污染胃肠道的假设。
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引用次数: 0
Imaging salivary glands post external radiation beam therapy of head and neck tumours 头颈部肿瘤放射治疗后唾液腺成像
Pub Date : 2018-01-01 DOI: 10.21767/amj.2018.3412
Mpumelelo Nyathi
Background Radiation therapy using external radiation beam is an established treatment for head and neck cancers. However, salivary glands are exposed leading to severe impairment of oral health. In order to devise patient care strategies, clinicians can measure the degree of salivary gland impairment using various imaging modalities. Aims The study aimed determining the best imaging modality for measuring salivary glands impairment post external radiation beam therapy of head and neck tumours. Methods A systematic literature review, performed using Google and Science Direct.com search engines. Publications in English on salivary gland imaging modalities post external radiation beam therapy of head and neck cancers were selected. Information on advantages and disadvantages of the imaging modalities was documented. Results The study established that the Magnetic Resonance Imaging (MRI), Computer Tomography (CT), Ultra Sound (US) depict structural changes while salivary gland scintigraphy provides functional information. It was also established that the obstruction of the salivary glands can be measured using Magnetic Resonance – Sialography. Conclusion The salivary gland scintigraphy technique is the most sensitive of all salivary gland imaging modalities with the ability to detect slight parenchymal injuries well before structural changes can be seen using the MRI, CT and US. However, when evaluating the obstruction of the salivary glands ducts, the Magnetic Resonance-Sialography modality offers the best option.
背景:使用外部放射束的放射治疗是头颈部癌症的一种既定治疗方法。然而,唾液腺的暴露导致口腔健康严重受损。为了制定患者护理策略,临床医生可以使用各种成像方式测量唾液腺损伤的程度。目的探讨头颈部肿瘤放射治疗后唾液腺损伤的最佳成像方式。方法采用谷歌和Science Direct.com搜索引擎进行系统文献综述。选择有关头颈癌外部放射束治疗后唾液腺成像方式的英文出版物。记录了有关成像方式的优缺点的信息。结果磁共振成像(MRI)、计算机断层扫描(CT)、超声成像(US)可以描述涎腺的结构变化,而唾液腺显像可以提供功能信息。同时也证实了唾液腺阻塞可以用磁共振唾液造影来测量。结论唾液腺闪烁成像技术是所有唾液腺成像方式中最敏感的,能够在MRI、CT和US发现结构变化之前发现轻微的实质损伤。然而,当评估唾液腺导管阻塞时,磁共振-唾液造影模式提供了最好的选择。
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引用次数: 0
Sources of information in health education: A cross-sectional study in Portuguese university students 健康教育中的信息来源:葡萄牙大学生的横断面研究
Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2018.3435
Paulo Santos, L. Sá, Luciana Couto, A. Hespanhol
Background Literacy is a public health priority. The way people access health information is changing. It’s crucial to understand this movement towards new communication tools, to better deal with it. Aims To describe the sources of health information in younger population. Methods Cross-sectional study of a sample of Portuguese university students, by survey, asking for the sources of information in health issues, and crossing it with the literacy levels. Results We surveyed 485 participants (77.5 per cent females; median age 23 years). The main source of information was the internet (78.8 per cent; 95 per cent CI:75.1–82.4 per cent), followed by health providers and by family. A linear regression model adjusted for age, gender and having education in health issues, showed that using the internet is adversely associated with the literacy score. Conclusion The internet is preferred to search for health information, but ineffective to improve the literacy rate, making us to conclude for the need of increasing the quality of available resources.
扫盲是公共卫生的优先事项。人们获取健康信息的方式正在发生变化。理解这种向新通信工具发展的趋势,更好地应对它,是至关重要的。目的描述年轻人群健康信息的来源。方法对葡萄牙大学生样本进行横断面研究,通过调查,询问健康问题的信息来源,并将其与文化水平交叉。结果我们调查了485名参与者(77.5%为女性;中位年龄23岁)。信息的主要来源是互联网(78.8%;95%置信区间:75.1 - 82.4%),其次是保健提供者和家庭。对年龄、性别和健康问题教育程度进行调整后的线性回归模型显示,使用互联网与读写能力得分呈负相关。结论互联网是健康信息搜索的首选,但对提高识字率无效,因此我们认为需要提高可用资源的质量。
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引用次数: 11
Effect of hyperemesis gravidarum on child neurodevelopment 妊娠剧吐对儿童神经发育的影响
Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2018.3476
G. Koren, Rana Cohen
Background Pregnancy outcome following hyperemesis gravidarum (HG) has been sparsely reported. This review article aims at critically reviewing the first prospective study of foetal longterm neurodevelopment after maternal HG. Aims This review aimed at critically appraising the first prospective human study that aimed at investigating long term child neurodevelopment after exposure to maternal HG.
背景:妊娠剧吐(HG)后的妊娠结局报道很少。这篇综述文章旨在批判性地回顾第一项关于母体汞中毒后胎儿长期神经发育的前瞻性研究。目的本综述旨在批判性地评价第一项旨在调查母体汞中毒后儿童长期神经发育的前瞻性人类研究。
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引用次数: 2
Rehabilitation of an atrophic jaw with three short implants and a customized milled bar overdenture 用三个短种植体和定制的磨条覆盖义齿修复萎缩颌骨
Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2018.3537
António Sérgio Silva, J. Sá, C. Aroso, E. Santos, Luís Neves, J. Mendes
Edentulism is frequently observed in older individuals, and edentulous patients with conventional prostheses have reported lack of retention, support, stability, and chewing and phonation failures. Overdentures are a good option for rehabilitation of edentulous patients. Two or more implants supporting a milled bar with attachments may be used for rehabilitation of these patients, since this arrangement allows very limited rotation and vertical movement, thereby increasing patient satisfaction. This report describes a clinical case involving oral rehabilitation of an atrophic jaw with three short implants and a customized milled bar overdenture.
无牙症在老年人中很常见,无牙患者使用传统义齿后缺乏固位、支撑、稳定性以及咀嚼和发声失败。复盖义齿是无牙患者康复的良好选择。由于这种安排允许非常有限的旋转和垂直运动,因此可以使用两个或更多的植入物来支持带有附件的磨杆,从而提高患者的满意度。本报告描述了一个临床病例涉及口腔康复萎缩颌骨与三个短种植和定制磨棒覆盖义齿。
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引用次数: 0
Gallbladder polyps between ultrasound and histopathology 胆囊息肉超声与组织病理学之间的关系
Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2017.3300
A. R. A. Manasra, H. Qandeel, Mohammad Al Hurani, Tagleb S. Mazahreh, S. Hamouri
Background Gallbladder polyps (GBP) are rare. Ultrasound is the most widely used screening method for Gallbladder pathology. Aims We aim to analyse polyps identified in gallbladders removed by laparoscopy over a 14-year period, and to assess the ability of conventional ultrasound to differentiate GBPs from stones. Methods This is a retrospective study of 11,391 patients who underwent laparoscopic cholecystectomy from 2002–2016. Data concerning patients' characteristics, preoperative ultrasound findings, number and size of lesions, histologic features of polyps and gallbladder were collected. Results Forty-six patients had GBP(s) (0.4 per cent). Mean age was 54(range 17-85), 67.4 per cent were females. Body mass index (BMI) was 30 (range 19-43). GBP(s) were single in 63 per cent of cases. Polyp size ranged between 0.2 and 2.2cm (average 1cm). Preoperative ultrasound successfully differentiated polyps from stones in nine cases (20 per cent). The most common histopathologic pattern was hyperplastic polyps in 18 cases (39.1), followed by cholesterol polyps (28.3 per cent), adenomyoma (13 per cent) and adenoma (8.7 per cent). The rest (10.9 per cent) were malignant polyps (adenocarcinoma). Polyps were associated with chronic cholecystitis in 40/46 patients. Conclusion GBPs are rare. Hyperplastic polyps are the commonest in our region, probably due to chronic inflammation induced by gallstones. Although ultrasound seems to be sensitive to gallbladder lesions; its utility to differentiate polyps from stones is relatively low. Since one tenth of polyps were hiding malignancy, cholecystectomy is advised especially in elderly people.
胆囊息肉(GBP)是一种罕见的疾病。超声是胆囊病理检查中应用最广泛的筛查方法。我们的目的是分析14年来腹腔镜胆囊切除术中发现的息肉,并评估常规超声区分GBPs和结石的能力。方法对2002-2016年11391例腹腔镜胆囊切除术患者进行回顾性研究。收集患者的特点、术前超声表现、病变的数量和大小、息肉和胆囊的组织学特征。结果46例患者有GBP(s)(0.4%)。平均年龄54岁(17-85岁),女性占67.4%。身体质量指数(BMI)为30(范围19-43)。GBP(s)在63%的情况下是单身。息肉大小在0.2 ~ 2.2cm之间(平均1cm)。术前超声成功区分息肉和结石9例(20%)。最常见的组织病理类型是增生性息肉,18例(39.1%),其次是胆固醇息肉(28.3%),腺肌瘤(13%)和腺瘤(8.7%)。其余(10.9%)为恶性息肉(腺癌)。46例患者中有40例伴有慢性胆囊炎。结论GBPs少见。增生性息肉是我们地区最常见的,可能是由于胆结石引起的慢性炎症。虽然超声似乎对胆囊病变很敏感;它在区分息肉和结石方面的效用相对较低。由于十分之一的息肉隐藏着恶性肿瘤,因此建议对老年人进行胆囊切除术。
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引用次数: 1
The effect of maternal position on foetal middle cerebral to umbilical artery resistance index ratio 产妇体位对胎儿大脑中动脉与脐动脉阻力指数比值的影响
Pub Date : 2018-01-01 DOI: 10.21767/amj.2018.3251
N. Farshchian, M. Salehi, Parisa Bahrami Kamangar
Background Foetal distress is the distress of the foetus prior to or during labour and is used to describe foetal hypoxia. Aims As exact determination of foetal middle cerebral artery (MCA) to umbilical artery resistance index (RI) ratio has important role in the diagnosis of foetal distress, any factor that can alter this ratio can affect diagnosis of foetal distress. Therefore, we decided to investigate the role of maternal position and its effect on foetal MCA/umbilical artery RI ratio. Methods In this quasi-experimental study, a total of 27 pregnant mothers who aged 17 to 43 years and gestational age range of 26 to 39 weeks were studied by colour Doppler ultrasound. RI of the MCA and umbilical artery was measured at three positions, namely supine, right lateral decubitus, and left lateral decubitus positions. Results There was no significant difference regarding MCA/umbilical artery RI ratio between supine and right lateral decubitus (P=0.48), right and left lateral decubitus (P=0.67), and supine vs. left lateral decubitus (P=0.39). Likewise, no difference was seen regarding MCA/umbilical artery pulsatility index (PI) between supine and right lateral decubitus (P=0.20), right and left lateral decubitus (P=0.35), and supine vs. left lateral decubitus (P=0.80). Conclusion Maternal position did not have significant effect on MCA/umbilical artery RI ratio.
胎儿窘迫是指分娩前或分娩过程中胎儿的窘迫,用于描述胎儿缺氧。目的胎儿大脑中动脉(MCA)与脐动脉阻力指数(RI)比值的准确测定对胎儿窘迫的诊断具有重要意义,任何改变该比值的因素都可能影响胎儿窘迫的诊断。因此,我们决定研究产妇位置及其对胎儿MCA/脐动脉RI比率的影响。方法对27例17 ~ 43岁、孕龄26 ~ 39周的孕妇进行彩色多普勒超声检查。分别在仰卧位、右侧卧位和左侧卧位测量MCA和脐动脉的RI。结果仰卧位与右侧侧卧位、右侧侧卧位与左侧侧卧位、右侧侧卧位与左侧侧卧位的MCA/脐动脉RI比值无显著差异(P=0.48)。同样,在仰卧位与右侧侧卧位(P=0.20)、右侧侧卧位与左侧侧卧位(P=0.35)以及左侧侧卧位与仰卧位(P=0.80)之间的MCA/脐动脉脉搏指数(PI)也没有差异。结论产妇体位对MCA/脐动脉RI比值无显著影响。
{"title":"The effect of maternal position on foetal middle cerebral to umbilical artery resistance index ratio","authors":"N. Farshchian, M. Salehi, Parisa Bahrami Kamangar","doi":"10.21767/amj.2018.3251","DOIUrl":"https://doi.org/10.21767/amj.2018.3251","url":null,"abstract":"Background Foetal distress is the distress of the foetus prior to or during labour and is used to describe foetal hypoxia. Aims As exact determination of foetal middle cerebral artery (MCA) to umbilical artery resistance index (RI) ratio has important role in the diagnosis of foetal distress, any factor that can alter this ratio can affect diagnosis of foetal distress. Therefore, we decided to investigate the role of maternal position and its effect on foetal MCA/umbilical artery RI ratio. Methods In this quasi-experimental study, a total of 27 pregnant mothers who aged 17 to 43 years and gestational age range of 26 to 39 weeks were studied by colour Doppler ultrasound. RI of the MCA and umbilical artery was measured at three positions, namely supine, right lateral decubitus, and left lateral decubitus positions. Results There was no significant difference regarding MCA/umbilical artery RI ratio between supine and right lateral decubitus (P=0.48), right and left lateral decubitus (P=0.67), and supine vs. left lateral decubitus (P=0.39). Likewise, no difference was seen regarding MCA/umbilical artery pulsatility index (PI) between supine and right lateral decubitus (P=0.20), right and left lateral decubitus (P=0.35), and supine vs. left lateral decubitus (P=0.80). Conclusion Maternal position did not have significant effect on MCA/umbilical artery RI ratio.","PeriodicalId":46823,"journal":{"name":"Australasian Medical Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68183812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Influence of different orthodontic brackets and chemical preparations of ceramic crowns on shear bond strength 不同托槽及化学制剂对陶瓷冠剪切粘结强度的影响
Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2018.3318
Blerim Mehmeti, Fehim Haliti, Bleron Azizi, J. Kelmendi, Donika Ilijazi Shahiqi, S. Jakovljević, S. Milošević
Background Bonding to ceramic restorations remains a major challenge to orthodontists, especially due to an increasing number of adults seeking orthodontic treatment. Aims The objective of this research was to investigate the influence of two chemical methods used for surface conditioning of ceramic crowns, on shear bond strength (SBS) of metallic and ceramic orthodontic brackets bonded to ceramic surfaces. Methods The study was conducted on 48 prepared specimens of metallic and ceramic orthodontic brackets bonded to ceramic crowns, conditioned with two different etching materials: hydrofluoric acid (HFA), or phosphoric acid, and subsequently, silane. SBS was tested using Universal Testing Machine. The samples were analysed using Scanning Electron Microscope, to determine adhesive remnant index (ARI). Statistical data was processed with ANOVA, and ARI was evaluated using x 2 test, with level of significance α=0.05. Results SBS values of the groups etched with HFA and silane, compared to the groups etched with phosphoric acid and silane, are not significantly increased. However, ceramic brackets show significantly higher SBS values than metallic brackets. Conclusion Both types of ceramic surface conditioning procedures have similar features and provide strong enough SBS values to realize the orthodontic treatment. Also, the assumption that only the type of bracket significantly affects the SBS value can be accepted.
结合陶瓷修复体仍然是正畸医生面临的主要挑战,特别是由于越来越多的成年人寻求正畸治疗。目的研究两种化学方法对金属和陶瓷正畸托槽与陶瓷表面的剪切结合强度(SBS)的影响。方法对48个金属和陶瓷正畸托槽固定在陶瓷冠上,用两种不同的蚀刻材料:氢氟酸(HFA)或磷酸,然后是硅烷进行研究。SBS采用万能试验机进行测试。用扫描电镜对样品进行分析,测定黏合剂残留指数(ARI)。统计资料采用方差分析处理,ARI采用x2检验,显著性水平α=0.05。结果与磷酸和硅烷腐蚀组相比,HFA和硅烷腐蚀组的SBS值没有显著升高。然而,陶瓷支架的SBS值明显高于金属支架。结论两种陶瓷表面调理方法具有相似的特点,均能提供足够强的SBS值来实现正畸治疗。此外,可以接受只有括号类型会显著影响SBS值的假设。
{"title":"Influence of different orthodontic brackets and chemical preparations of ceramic crowns on shear bond strength","authors":"Blerim Mehmeti, Fehim Haliti, Bleron Azizi, J. Kelmendi, Donika Ilijazi Shahiqi, S. Jakovljević, S. Milošević","doi":"10.21767/AMJ.2018.3318","DOIUrl":"https://doi.org/10.21767/AMJ.2018.3318","url":null,"abstract":"Background Bonding to ceramic restorations remains a major challenge to orthodontists, especially due to an increasing number of adults seeking orthodontic treatment. Aims The objective of this research was to investigate the influence of two chemical methods used for surface conditioning of ceramic crowns, on shear bond strength (SBS) of metallic and ceramic orthodontic brackets bonded to ceramic surfaces. Methods The study was conducted on 48 prepared specimens of metallic and ceramic orthodontic brackets bonded to ceramic crowns, conditioned with two different etching materials: hydrofluoric acid (HFA), or phosphoric acid, and subsequently, silane. SBS was tested using Universal Testing Machine. The samples were analysed using Scanning Electron Microscope, to determine adhesive remnant index (ARI). Statistical data was processed with ANOVA, and ARI was evaluated using x 2 test, with level of significance α=0.05. Results SBS values of the groups etched with HFA and silane, compared to the groups etched with phosphoric acid and silane, are not significantly increased. However, ceramic brackets show significantly higher SBS values than metallic brackets. Conclusion Both types of ceramic surface conditioning procedures have similar features and provide strong enough SBS values to realize the orthodontic treatment. Also, the assumption that only the type of bracket significantly affects the SBS value can be accepted.","PeriodicalId":46823,"journal":{"name":"Australasian Medical Journal","volume":"11 1","pages":"107-112"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68184154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Pulmonary rehabilitation in moderate pulmonary hypertension 中度肺动脉高压的肺康复治疗
Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2018.3467
J. Peña, Nathalie Torres del Castillo, J. C. Valencia, Vicente B enavides Cordoba
Introduction Pulmonary Rehabilitation has been used in Chronic Obstructive Pulmonary Disease, becoming an essential strategy in its treatment; however, in pathologies such as Pulmonary Hypertension, the benefits in the quality of life and tolerance to the effort are still discussed. Therefore, the aim of this case report is to evaluate the effect of an integral pulmonary rehabilitation intervention in a patient with moderate pulmonary hypertension secondary to respiratory disease. Case details A patient with moderate pulmonary hypertension secondary to lung disease, who attended an integral pulmonary rehabilitation program during 8 weeks of muscle training, aerobic exercise, breathing exercises, individualized education and psychological/ nutritional counselling were performed. Results Significant improvement in tolerance to effort, reduction of symptoms and health-related quality of life after the intervention was achieved. Conclusion Pulmonary rehabilitation in moderate pulmonary hypertension generated beneficial changes in terms of symptoms and functionality in the patient reported.
肺部康复治疗已成为慢性阻塞性肺疾病治疗的重要手段;然而,在诸如肺动脉高压等疾病中,对生活质量和耐受性的益处仍在讨论中。因此,本病例报告的目的是评估综合肺部康复干预对继发于呼吸系统疾病的中度肺动脉高压患者的效果。病例资料1例继发于肺部疾病的中度肺动脉高压患者,在8周的肌肉训练、有氧运动、呼吸运动、个体化教育和心理/营养咨询期间进行了综合肺部康复计划。结果干预后患者的耐受力、症状减轻和健康相关生活质量均有显著改善。结论中度肺动脉高压患者的肺康复在症状和功能方面产生了有益的变化。
{"title":"Pulmonary rehabilitation in moderate pulmonary hypertension","authors":"J. Peña, Nathalie Torres del Castillo, J. C. Valencia, Vicente B enavides Cordoba","doi":"10.21767/AMJ.2018.3467","DOIUrl":"https://doi.org/10.21767/AMJ.2018.3467","url":null,"abstract":"Introduction Pulmonary Rehabilitation has been used in Chronic Obstructive Pulmonary Disease, becoming an essential strategy in its treatment; however, in pathologies such as Pulmonary Hypertension, the benefits in the quality of life and tolerance to the effort are still discussed. Therefore, the aim of this case report is to evaluate the effect of an integral pulmonary rehabilitation intervention in a patient with moderate pulmonary hypertension secondary to respiratory disease. Case details A patient with moderate pulmonary hypertension secondary to lung disease, who attended an integral pulmonary rehabilitation program during 8 weeks of muscle training, aerobic exercise, breathing exercises, individualized education and psychological/ nutritional counselling were performed. Results Significant improvement in tolerance to effort, reduction of symptoms and health-related quality of life after the intervention was achieved. Conclusion Pulmonary rehabilitation in moderate pulmonary hypertension generated beneficial changes in terms of symptoms and functionality in the patient reported.","PeriodicalId":46823,"journal":{"name":"Australasian Medical Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68186317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Amelanotic melanoma of the skin – detailed review of the problem 皮肤无色素黑色素瘤的详细问题综述
Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2018.3511
S. Strashilov, V. Kirov, A. Yordanov, Yoana I. Simeonova, Miroslava Mihailova Strashilova
Background Malignant melanoma (MM) of the skin accounts for about one per cent of all malignancies in humans. Amelanotic melanoma is a rare tumour, diagnosed in eight per cent of all melanomas. Aims The study aimed to analyse our clinical experience with amelanotic MM of the skin and the statistical data from a retrospective five year analysis of pigmented and amelanotic types of skin melanoma. Furthermore, we compare our results to those from other teams' studies. To reach the corresponding in-depth conclusions. Methods The study included 151 patients with malignant melanoma of the skin, diagnosed and treated at Dr. Georgi Stranski University in Pleven, Bulgaria, between 2012 and 2016. All the patients signed informed consent forms. Results Of the 151 patients we studied, 14 (9.3 per cent) were diagnosed with amelanotic melanoma. The average Breslow thickness in patients with amelanotic MM was 4.2mm, while in pigmented MM patients it 2.1mm. Local recurrence rates (35.7 per cent) were higher in patients with amelanotic melanoma. Distant metastases were found in 39 of all tested patients with melanoma. Of the 14 patients with amelanotic MM, eight had such metastases. Conclusion Amelanotic melanoma was diagnosed too late. Local recurrences were six times as many as the ones diagnosed in pigment melanoma. Distant metastases were twice as many, and mortality rates were three times higher.
皮肤恶性黑色素瘤(MM)约占人类所有恶性肿瘤的1%。无色素黑色素瘤是一种罕见的肿瘤,占所有黑色素瘤的8%。目的:本研究旨在分析我们治疗无色素性皮肤MM的临床经验,以及回顾性分析5年来皮肤黑色素瘤的色素型和无色素型的统计数据。此外,我们将我们的研究结果与其他团队的研究结果进行比较。得出相应的深入结论。该研究纳入了151例皮肤恶性黑色素瘤患者,这些患者于2012年至2016年在保加利亚普列文的Georgi Stranski博士大学诊断和治疗。所有患者都签署了知情同意书。结果在我们研究的151例患者中,14例(9.3%)被诊断为无色素黑色素瘤。无色素MM患者的平均Breslow厚度为4.2mm,而色素MM患者的平均Breslow厚度为2.1mm。无色素黑色素瘤患者的局部复发率(35.7%)更高。在所有接受检测的黑色素瘤患者中,有39例发现了远处转移。在14例无黑色素瘤MM患者中,8例发生了此类转移。结论无色素黑色素瘤诊断太晚。局部复发率是黑色素瘤患者的6倍。远处转移的病例是前者的两倍,死亡率是后者的三倍。
{"title":"Amelanotic melanoma of the skin – detailed review of the problem","authors":"S. Strashilov, V. Kirov, A. Yordanov, Yoana I. Simeonova, Miroslava Mihailova Strashilova","doi":"10.21767/AMJ.2018.3511","DOIUrl":"https://doi.org/10.21767/AMJ.2018.3511","url":null,"abstract":"Background Malignant melanoma (MM) of the skin accounts for about one per cent of all malignancies in humans. Amelanotic melanoma is a rare tumour, diagnosed in eight per cent of all melanomas. Aims The study aimed to analyse our clinical experience with amelanotic MM of the skin and the statistical data from a retrospective five year analysis of pigmented and amelanotic types of skin melanoma. Furthermore, we compare our results to those from other teams' studies. To reach the corresponding in-depth conclusions. Methods The study included 151 patients with malignant melanoma of the skin, diagnosed and treated at Dr. Georgi Stranski University in Pleven, Bulgaria, between 2012 and 2016. All the patients signed informed consent forms. Results Of the 151 patients we studied, 14 (9.3 per cent) were diagnosed with amelanotic melanoma. The average Breslow thickness in patients with amelanotic MM was 4.2mm, while in pigmented MM patients it 2.1mm. Local recurrence rates (35.7 per cent) were higher in patients with amelanotic melanoma. Distant metastases were found in 39 of all tested patients with melanoma. Of the 14 patients with amelanotic MM, eight had such metastases. Conclusion Amelanotic melanoma was diagnosed too late. Local recurrences were six times as many as the ones diagnosed in pigment melanoma. Distant metastases were twice as many, and mortality rates were three times higher.","PeriodicalId":46823,"journal":{"name":"Australasian Medical Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68186664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
期刊
Australasian Medical Journal
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