Pub Date : 2023-10-17DOI: 10.53730/ijhs.v7ns1.14596
Siddiq Mukkamil Ahmed, M. N. Divyarani, A. N. Roopa, S. M. Sowmya, Raj Mohammed, Rehan Baig, Samiyah Syeed Ahmed
Background: Mucormycosis is a rapidly progressive angioinvasive fungal infection which has a high rate of mortality and morbidity. Mucormycosis most commonly invades the nose and paranasal sinuses presenting as rhinosinusitis. We noted an upsurge in the number of patients affected with Mucormycosis during Covid-19 infection era. Aim: Our study aims to illustrate the histopathology of Mucormycosis in post-Covid-19 patients and also to study the fungal morphology by utilizing special stains. Materials and Methods: We prospectively analysed the histopathological findings of fungal elements in 260 different histopathological samples of mucormycosis in post-covid-19 patients. The clinical and histopathological findings were noted and tabulated. Statistical Analysis Used: The data collected was tabulated and coded in Microsoft excel. All the data of demographic and clinical characteristics were analysed by descriptive statistics and percentage. Tables and graphs were added wherever applicable. Results: Out of 260 cases analysed, most of the patients presented with periorbital swelling followed by headache and nasal block. Histopathologically, most of the cases showed chronic inflammatory reaction with wide areas of necrosis and granuloma formation. The fungal elements have been appreciated and sensitivity of different stains to appreciate the fungal structures have been compared.
{"title":"Histomorphological study of mucormycosis in COVID-19 patients","authors":"Siddiq Mukkamil Ahmed, M. N. Divyarani, A. N. Roopa, S. M. Sowmya, Raj Mohammed, Rehan Baig, Samiyah Syeed Ahmed","doi":"10.53730/ijhs.v7ns1.14596","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14596","url":null,"abstract":"Background: Mucormycosis is a rapidly progressive angioinvasive fungal infection which has a high rate of mortality and morbidity. Mucormycosis most commonly invades the nose and paranasal sinuses presenting as rhinosinusitis. We noted an upsurge in the number of patients affected with Mucormycosis during Covid-19 infection era. Aim: Our study aims to illustrate the histopathology of Mucormycosis in post-Covid-19 patients and also to study the fungal morphology by utilizing special stains. Materials and Methods: We prospectively analysed the histopathological findings of fungal elements in 260 different histopathological samples of mucormycosis in post-covid-19 patients. The clinical and histopathological findings were noted and tabulated. Statistical Analysis Used: The data collected was tabulated and coded in Microsoft excel. All the data of demographic and clinical characteristics were analysed by descriptive statistics and percentage. Tables and graphs were added wherever applicable. Results: Out of 260 cases analysed, most of the patients presented with periorbital swelling followed by headache and nasal block. Histopathologically, most of the cases showed chronic inflammatory reaction with wide areas of necrosis and granuloma formation. The fungal elements have been appreciated and sensitivity of different stains to appreciate the fungal structures have been compared.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135992896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-12DOI: 10.53730/ijhs.v7ns1.14599
Riffat Naseem, Muhammad Israr, Shahzaib Khan, Muhammad Aarab, Muhammad Yousuf, Hafiz Zia Ullah Abid
The morbidity, death, and medication resistance caused by Mycobacterium tuberculosis are global health concern. The Gene Xpert is employed to diagnose TB early and find pyrazinamide (PYR) resistance at the same time. Our goal was to examine the clinical TB situation at Faisalabad's tertiary care institutions and to use Gene Xpert to determine the prevalence of TB and the drug resistance pattern. In this research, 135 samples from probable TB patients were included, and Gene Xpert identified 127 samples as positive. The gender, age group (50 years), sample type (sputum and pleural), and number of M. tuberculosis by ct value (cycle threshold) were all taken into consideration when categorizing the samples. The findings of the current investigation revealed a significant positive frequency of TB in male patients and in the 31-50 years age ranges. Patients with TB had a high prevalence of M. tuberculosis in the low and medium categories. 16 of the 127 TB patients who tested positive for the disease had pyrazinamide resistance. Our study concluded that Gene Xpert is a useful method for quickly diagnosing and treating TB since it can quickly detect M. tuberculosis and pyrazinamide resistance.
{"title":"Investigation of variations of pyrazinamide resistance and gene Xpert-based molecular typing in tuberculosis patients","authors":"Riffat Naseem, Muhammad Israr, Shahzaib Khan, Muhammad Aarab, Muhammad Yousuf, Hafiz Zia Ullah Abid","doi":"10.53730/ijhs.v7ns1.14599","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14599","url":null,"abstract":"The morbidity, death, and medication resistance caused by Mycobacterium tuberculosis are global health concern. The Gene Xpert is employed to diagnose TB early and find pyrazinamide (PYR) resistance at the same time. Our goal was to examine the clinical TB situation at Faisalabad's tertiary care institutions and to use Gene Xpert to determine the prevalence of TB and the drug resistance pattern. In this research, 135 samples from probable TB patients were included, and Gene Xpert identified 127 samples as positive. The gender, age group (50 years), sample type (sputum and pleural), and number of M. tuberculosis by ct value (cycle threshold) were all taken into consideration when categorizing the samples. The findings of the current investigation revealed a significant positive frequency of TB in male patients and in the 31-50 years age ranges. Patients with TB had a high prevalence of M. tuberculosis in the low and medium categories. 16 of the 127 TB patients who tested positive for the disease had pyrazinamide resistance. Our study concluded that Gene Xpert is a useful method for quickly diagnosing and treating TB since it can quickly detect M. tuberculosis and pyrazinamide resistance.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136012863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to investigate the clinical efficacy of transarterial chemoembolization (TACE) in conjunction with terminal branches portal vein embolization (TBPVE) in the context of planned hepatectomy. A cohort of five patients afflicted by primary hepatocellular carcinoma who were deemed unsuitable candidates for primary surgical resection was gathered from August 2019 to December 2021. Following the application of TACE in combination with TBPVE as a therapeutic intervention, we observed postoperative general reactions, alterations in tumor biomarkers, hyperplasia of future liver remnant (FLR), and subsequent surgical resection. All patients successfully underwent the combined TACE and TBPVE procedure, achieving a technical success rate of 100%. One week after TACE, alpha-fetoprotein (AFP) levels decreased from 38.52±49.21 to 25.27±37.94 μg/L, and Protein Induced by Vitamin K Absence or Antagonist (PIVKA) levels decreased from 1689.30±1663.83 to 219.03±228.10 μg/L. Two weeks post-TBPVE, FLR exhibited an increment from 350.80±41.17 to 476.00±57.91 mL. The ratio of FLR to standard liver volume (SLV) increased from 30.94%±3.63% to 42.03%±5.62%. The combined application of TACE and TBPVE not only effectively manages tumor progression but also augments the FLR, thereby affording patients with a limited future liver remnant an opportunity for surgical resection of hepatocellular carcinoma.
{"title":"Clinical application of transarterial chemoembolization combined with terminal branches portal vein embolization in planned hepatectomy","authors":"Guoqing Zhu, Wenhao Hu, Wei Xiang, Junwei Ni, Liyang Dong","doi":"10.53730/ijhs.v7ns1.14563","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14563","url":null,"abstract":"This study aimed to investigate the clinical efficacy of transarterial chemoembolization (TACE) in conjunction with terminal branches portal vein embolization (TBPVE) in the context of planned hepatectomy. A cohort of five patients afflicted by primary hepatocellular carcinoma who were deemed unsuitable candidates for primary surgical resection was gathered from August 2019 to December 2021. Following the application of TACE in combination with TBPVE as a therapeutic intervention, we observed postoperative general reactions, alterations in tumor biomarkers, hyperplasia of future liver remnant (FLR), and subsequent surgical resection. All patients successfully underwent the combined TACE and TBPVE procedure, achieving a technical success rate of 100%. One week after TACE, alpha-fetoprotein (AFP) levels decreased from 38.52±49.21 to 25.27±37.94 μg/L, and Protein Induced by Vitamin K Absence or Antagonist (PIVKA) levels decreased from 1689.30±1663.83 to 219.03±228.10 μg/L. Two weeks post-TBPVE, FLR exhibited an increment from 350.80±41.17 to 476.00±57.91 mL. The ratio of FLR to standard liver volume (SLV) increased from 30.94%±3.63% to 42.03%±5.62%. The combined application of TACE and TBPVE not only effectively manages tumor progression but also augments the FLR, thereby affording patients with a limited future liver remnant an opportunity for surgical resection of hepatocellular carcinoma.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135045843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to investigate the clinical efficacy of transarterial chemoembolization (TACE) in conjunction with terminal branches portal vein embolization (TBPVE) in the context of planned hepatectomy. A cohort of five patients afflicted by primary hepatocellular carcinoma who were deemed unsuitable candidates for primary surgical resection was gathered from August 2019 to December 2021. Following the application of TACE in combination with TBPVE as a therapeutic intervention, we observed postoperative general reactions, alterations in tumor biomarkers, hyperplasia of future liver remnant (FLR), and subsequent surgical resection. All patients successfully underwent the combined TACE and TBPVE procedure, achieving a technical success rate of 100%. One week after TACE, alpha-fetoprotein (AFP) levels decreased from 38.52±49.21 to 25.27±37.94 μg/L, and Protein Induced by Vitamin K Absence or Antagonist (PIVKA) levels decreased from 1689.30±1663.83 to 219.03±228.10 μg/L. Two weeks post-TBPVE, FLR exhibited an increment from 350.80±41.17 to 476.00±57.91 mL. The ratio of FLR to standard liver volume (SLV) increased from 30.94%±3.63% to 42.03%±5.62%. The combined application of TACE and TBPVE not only effectively manages tumor progression but also augments the FLR, thereby affording patients with a limited future liver remnant an opportunity for surgical resection of hepatocellular carcinoma.
{"title":"Clinical application of transarterial chemoembolization combined with terminal branches portal vein embolization in planned hepatectomy","authors":"Guoqing Zhu, Wenhao Hu, Wei Xiang, Junwei Ni, Liyang Dong","doi":"10.53730/ijhs.v7n3.14563","DOIUrl":"https://doi.org/10.53730/ijhs.v7n3.14563","url":null,"abstract":"This study aimed to investigate the clinical efficacy of transarterial chemoembolization (TACE) in conjunction with terminal branches portal vein embolization (TBPVE) in the context of planned hepatectomy. A cohort of five patients afflicted by primary hepatocellular carcinoma who were deemed unsuitable candidates for primary surgical resection was gathered from August 2019 to December 2021. Following the application of TACE in combination with TBPVE as a therapeutic intervention, we observed postoperative general reactions, alterations in tumor biomarkers, hyperplasia of future liver remnant (FLR), and subsequent surgical resection. All patients successfully underwent the combined TACE and TBPVE procedure, achieving a technical success rate of 100%. One week after TACE, alpha-fetoprotein (AFP) levels decreased from 38.52±49.21 to 25.27±37.94 μg/L, and Protein Induced by Vitamin K Absence or Antagonist (PIVKA) levels decreased from 1689.30±1663.83 to 219.03±228.10 μg/L. Two weeks post-TBPVE, FLR exhibited an increment from 350.80±41.17 to 476.00±57.91 mL. The ratio of FLR to standard liver volume (SLV) increased from 30.94%±3.63% to 42.03%±5.62%. The combined application of TACE and TBPVE not only effectively manages tumor progression but also augments the FLR, thereby affording patients with a limited future liver remnant an opportunity for surgical resection of hepatocellular carcinoma.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-08DOI: 10.53730/ijhs.v7n3.14490
Shengzhang Lin, Zhaohong Wang, Xufan Cai
It has been shown that ginsenosides can inhibit proliferation, migration, and invasion of pancreatic cancer (PC) cells, and promote apoptosis of PC cells. However, the potential mechanisms of ginseng in treating PC metastasis (PCM) have not been fully elucidated. In this study, we employed an integrated bioinformatics approach of network pharmacology analysis. By selecting common targets of diseases and drugs, a drug-component-target-disease network was constructed to analyze the biological functions and signaling pathways involved in the targets. A total of 6 PC samples were includedd, which were divided into primary PC group (PANC-1, n=3) and metastatic PC group. A total of 9263 differentially expressed genes (DEGs) and 14 PC target genes were identified. According to the network pharmacology analysis, we found that ginsenoside Rg3 was associated with the treatment of PCM and identified 6 potential targets. Among them, CD44, EGFR, KRAS, and PRNP were the main DEGs related to the treatment of PC by ginsenoside Rg3. These genes were mainly enriched in the Proteoglycans in Cancer pathway, and KRAS, EGFR, and CD44 were upregulated in the pathway, which may be affected by the ginsenoside Rg3. This provides a new direction for further research on the mechanisms of ginseng in PCM.
{"title":"Mechanisms of ginseng in pancreatic cancer metastasis","authors":"Shengzhang Lin, Zhaohong Wang, Xufan Cai","doi":"10.53730/ijhs.v7n3.14490","DOIUrl":"https://doi.org/10.53730/ijhs.v7n3.14490","url":null,"abstract":"It has been shown that ginsenosides can inhibit proliferation, migration, and invasion of pancreatic cancer (PC) cells, and promote apoptosis of PC cells. However, the potential mechanisms of ginseng in treating PC metastasis (PCM) have not been fully elucidated. In this study, we employed an integrated bioinformatics approach of network pharmacology analysis. By selecting common targets of diseases and drugs, a drug-component-target-disease network was constructed to analyze the biological functions and signaling pathways involved in the targets. A total of 6 PC samples were includedd, which were divided into primary PC group (PANC-1, n=3) and metastatic PC group. A total of 9263 differentially expressed genes (DEGs) and 14 PC target genes were identified. According to the network pharmacology analysis, we found that ginsenoside Rg3 was associated with the treatment of PCM and identified 6 potential targets. Among them, CD44, EGFR, KRAS, and PRNP were the main DEGs related to the treatment of PC by ginsenoside Rg3. These genes were mainly enriched in the Proteoglycans in Cancer pathway, and KRAS, EGFR, and CD44 were upregulated in the pathway, which may be affected by the ginsenoside Rg3. This provides a new direction for further research on the mechanisms of ginseng in PCM.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135250979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-08DOI: 10.53730/ijhs.v7ns1.14490
Zhaohong Wang, Xufan Cai, Shengzhang Lin
It has been shown that ginsenosides can inhibit proliferation, migration, and invasion of pancreatic cancer (PC) cells, and promote apoptosis of PC cells. However, the potential mechanisms of ginseng in treating PC metastasis (PCM) have not been fully elucidated. In this study, we employed an integrated bioinformatics approach of network pharmacology analysis. By selecting common targets of diseases and drugs, a drug-component-target-disease network was constructed to analyze the biological functions and signaling pathways involved in the targets. A total of 6 PC samples were includedd, which were divided into primary PC group (PANC-1, n=3) and metastatic PC group. A total of 9263 differentially expressed genes (DEGs) and 14 PC target genes were identified. According to the network pharmacology analysis, we found that ginsenoside Rg3 was associated with the treatment of PCM and identified 6 potential targets. Among them, CD44, EGFR, KRAS, and PRNP were the main DEGs related to the treatment of PC by ginsenoside Rg3. These genes were mainly enriched in the Proteoglycans in Cancer pathway, and KRAS, EGFR, and CD44 were upregulated in the pathway, which may be affected by the ginsenoside Rg3. This provides a new direction for further research on the mechanisms of ginseng in PCM.
{"title":"Mechanisms of ginseng in pancreatic cancer metastasis","authors":"Zhaohong Wang, Xufan Cai, Shengzhang Lin","doi":"10.53730/ijhs.v7ns1.14490","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14490","url":null,"abstract":"It has been shown that ginsenosides can inhibit proliferation, migration, and invasion of pancreatic cancer (PC) cells, and promote apoptosis of PC cells. However, the potential mechanisms of ginseng in treating PC metastasis (PCM) have not been fully elucidated. In this study, we employed an integrated bioinformatics approach of network pharmacology analysis. By selecting common targets of diseases and drugs, a drug-component-target-disease network was constructed to analyze the biological functions and signaling pathways involved in the targets. A total of 6 PC samples were includedd, which were divided into primary PC group (PANC-1, n=3) and metastatic PC group. A total of 9263 differentially expressed genes (DEGs) and 14 PC target genes were identified. According to the network pharmacology analysis, we found that ginsenoside Rg3 was associated with the treatment of PCM and identified 6 potential targets. Among them, CD44, EGFR, KRAS, and PRNP were the main DEGs related to the treatment of PC by ginsenoside Rg3. These genes were mainly enriched in the Proteoglycans in Cancer pathway, and KRAS, EGFR, and CD44 were upregulated in the pathway, which may be affected by the ginsenoside Rg3. This provides a new direction for further research on the mechanisms of ginseng in PCM.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135198051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-04DOI: 10.53730/ijhs.v7ns1.14588
Loai. N. Said, Elham A. Al Atrash
Induction of labor may be necessary in around twenty-five to thirty percent of a woman's subsequent pregnancies when she has already given birth through cesarean section. During our research, the objective had been to ascertain the rate of spontaneous vaginal birth, rate of cesarean section, and rate of complications that followed the induction of labor with transcervical foley catheter in females who had previously had 1 cesarean section. This retrospective cohort trial was performed in the largest city in Palestine at a tertiary teaching hospital. In subsequent pregnancy, pregnant cases with a history of a prior CS delivery (n = 306) underwent labor induction at term with a Foley catheter. Women who underwent labor induction with transcervical foley catheter at Al-Ahli Hospital in Hebron, Palestine. From April 2017 until March 2020. Our research revealed that 46.7 percent of women had spontaneous vaginal births, 14.4 percent had assisted vaginal births, and one woman experienced uterine rupture. The frequency of postpartum hemorrhage is 30 percent, the most prevalent complication. 10 percent and 5 percent of mothers experienced intrapartum and postpartum infections, correspondingly. 5% of newborns had a confirmed infection, and there was one perinatal fatality related to uterine rupture.
{"title":"Foley catheter for induction of labor after cesarean section","authors":"Loai. N. Said, Elham A. Al Atrash","doi":"10.53730/ijhs.v7ns1.14588","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14588","url":null,"abstract":"Induction of labor may be necessary in around twenty-five to thirty percent of a woman's subsequent pregnancies when she has already given birth through cesarean section. During our research, the objective had been to ascertain the rate of spontaneous vaginal birth, rate of cesarean section, and rate of complications that followed the induction of labor with transcervical foley catheter in females who had previously had 1 cesarean section. This retrospective cohort trial was performed in the largest city in Palestine at a tertiary teaching hospital. In subsequent pregnancy, pregnant cases with a history of a prior CS delivery (n = 306) underwent labor induction at term with a Foley catheter. Women who underwent labor induction with transcervical foley catheter at Al-Ahli Hospital in Hebron, Palestine. From April 2017 until March 2020. Our research revealed that 46.7 percent of women had spontaneous vaginal births, 14.4 percent had assisted vaginal births, and one woman experienced uterine rupture. The frequency of postpartum hemorrhage is 30 percent, the most prevalent complication. 10 percent and 5 percent of mothers experienced intrapartum and postpartum infections, correspondingly. 5% of newborns had a confirmed infection, and there was one perinatal fatality related to uterine rupture.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135592504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joyce Osebe Kenyanya, Gideon Kikuvi, Peter Wanzala, Josephat Nyagero
Purpose: To determine maternal factors associated with low birth weight among neonates born at Thika Level Five Hospital in Kiambu County, Kenya.
Methodology: Cross sectional convergent design was employed. The target group composed of mothers who delivered in the hospital during the study period (July-August, 2019). Census method was used to recruit participants for a quantitative study. Purposive sampling was used to select participants for FGDs and KIIs. Sample size was determined using the Cochran formula. Desired sample size was 210 mothers which was adjusted to 215 participants. Independent variables included: socio-demographic, socio-economic, socio-cultural, behavioral, and health of the mothers. Dependent variable was LBW which was classified further into LBW, very LBW, extremely LBW. (UNICEF, 2010). Quantitative and qualitative data were analyzed using Stata statistical version 14, logistic regression and NVivo version 14 respectively,
Findings: ≥35 years of mothers OR=13.67, p=0.018, CL [1.55-120.12] and the second born children OR=2.98; p=0.025; CL [1.15-7.73] were associated with the overall LBW. Secondary level education OR=0.35; p=0.03; CL [0.14-0.91] was a protection against LBW. Meru OR=17.429, p=0.016, CI [1.7162-176.991] and other tribes OR=10.479, p=0.048, CI [1.025-107.124] were associated with low birth weight. Hypertension OR=3.59; p=0.038; CL [0.14-0.91] and malaria (OR=51.250, p=0.005, CL [3.185-822.132]) were associated with very LBW. ANC-attendance (OR=0.068, p=0.37, CL [0.0055-0.845]) was a protection against extremely LBW OR= 0.07; p=0,037; CL [0.01-0.85].
Unique Contribution to Theory, Policy and Practice: ≥35 years of mothers are risk factors for low birth weight. Second child is at risk of being low birth weight. Neonates of Meru origin and other minority ethnic groups in Thika are at risk of being LBW. Secondary level education is a protection against low birth weight. Hypertension and malaria are risk factors for very low birth weight. ANC-attendance is a protection against extremely low birth weight. The County Government of Kiambu should develop suitable strategies of strengthening maternal and child services at level one.
{"title":"Maternal Factors Associated with Low Birth Weight Among Neonates Born at Thika Level 5 Hospital in Kiambu County, Kenya","authors":"Joyce Osebe Kenyanya, Gideon Kikuvi, Peter Wanzala, Josephat Nyagero","doi":"10.47941/ijhs.1464","DOIUrl":"https://doi.org/10.47941/ijhs.1464","url":null,"abstract":"Purpose: To determine maternal factors associated with low birth weight among neonates born at Thika Level Five Hospital in Kiambu County, Kenya.
 Methodology: Cross sectional convergent design was employed. The target group composed of mothers who delivered in the hospital during the study period (July-August, 2019). Census method was used to recruit participants for a quantitative study. Purposive sampling was used to select participants for FGDs and KIIs. Sample size was determined using the Cochran formula. Desired sample size was 210 mothers which was adjusted to 215 participants. Independent variables included: socio-demographic, socio-economic, socio-cultural, behavioral, and health of the mothers. Dependent variable was LBW which was classified further into LBW, very LBW, extremely LBW. (UNICEF, 2010). Quantitative and qualitative data were analyzed using Stata statistical version 14, logistic regression and NVivo version 14 respectively,
 Findings: ≥35 years of mothers OR=13.67, p=0.018, CL [1.55-120.12] and the second born children OR=2.98; p=0.025; CL [1.15-7.73] were associated with the overall LBW. Secondary level education OR=0.35; p=0.03; CL [0.14-0.91] was a protection against LBW. Meru OR=17.429, p=0.016, CI [1.7162-176.991] and other tribes OR=10.479, p=0.048, CI [1.025-107.124] were associated with low birth weight. Hypertension OR=3.59; p=0.038; CL [0.14-0.91] and malaria (OR=51.250, p=0.005, CL [3.185-822.132]) were associated with very LBW. ANC-attendance (OR=0.068, p=0.37, CL [0.0055-0.845]) was a protection against extremely LBW OR= 0.07; p=0,037; CL [0.01-0.85].
 Unique Contribution to Theory, Policy and Practice: ≥35 years of mothers are risk factors for low birth weight. Second child is at risk of being low birth weight. Neonates of Meru origin and other minority ethnic groups in Thika are at risk of being LBW. Secondary level education is a protection against low birth weight. Hypertension and malaria are risk factors for very low birth weight. ANC-attendance is a protection against extremely low birth weight. The County Government of Kiambu should develop suitable strategies of strengthening maternal and child services at level one.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135695902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.53730/ijhs.v7ns1.14583
Ghidi Abdelkader
Sports medicine is the science that studies the most important injuries that athletes may be exposed to During discussions or training. It also shows how these injuries can be prevented. In this study, the researcher has revealed the importance of this science in the mathematical sciences field, and revealed the importance of studying this science, then to benefit from the previous experiences of doctors in this significant specialty. Also, integrating it into the modern training methodology. The researcher followed the descriptive approach. The results were clear about the importance and role of sports medicine in the field of sports.
{"title":"importance of sports medicine in modern sports among Algerian teams","authors":"Ghidi Abdelkader","doi":"10.53730/ijhs.v7ns1.14583","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14583","url":null,"abstract":"Sports medicine is the science that studies the most important injuries that athletes may be exposed to During discussions or training. It also shows how these injuries can be prevented. In this study, the researcher has revealed the importance of this science in the mathematical sciences field, and revealed the importance of studying this science, then to benefit from the previous experiences of doctors in this significant specialty. Also, integrating it into the modern training methodology. The researcher followed the descriptive approach. The results were clear about the importance and role of sports medicine in the field of sports.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135372850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-30DOI: 10.53730/ijhs.v7ns1.14579
Yamen Almeghawesh
Background: aberrant & accelerated wound-healing process that results in hypertrophic scarring causes extracellular matrix & collagen to deposit abnormally in the dermis. After tissue damage occurs, a defensive reaction called tissue repair occurs. Aim; in this review; we aimed to present the effectiveness of low-energy fractional carbon dioxide laser therapy in treating hypertrophic scars following surgery. Summary: A safe & effective approach for treating hypertrophic burn scars is fractional ablative CO2 laser therapy. Even though more treatment sessions have been necessary for satisfying outcomes, a big improvement can be seen after just one round of therapy. Combination therapy with other modalities can decrease the need for repetition of therapy as efficacy increases. Though, in some studies, combination therapy may shorten the duration of studied case downtime & in others, combination therapy may increase side effects. essential for laser energy setting needs to be adjusted for each hypertrophic scar condition. larger research population & longer follow-up period are recommended.
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