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[Impact of SARS-CoV-2 immunization on a breast screening programme.] [SARS-CoV-2免疫接种对乳腺筛查规划的影响]
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-08-31
Teresa Presa Abós, Irene Vicente Zapata, Miguel Chiva De Agustín

Objective: A common secondary effect after SARS-CoV-2 immunization is an increased in size of the axillary lymph nodes ipsilateral to the vaccinated site. Eventually, an increased in size of the axillary lymph nodes may lead to a misinterpretation of the breast screening mammogram, performed in asymptomatic women between the age 50 to 69 years old for early breast cancer diagnosis. The aim of our research was to evaluate the impact of the vaccination for SARS-CoV-2 in the breast screening programmes in terms of recall rates and number of false positive results. As a secondary purpose we would analysed the protocols adopted by different breast screening units around the world after SARS-CoV-2 vaccination.

Methods: Observational and retrospective study analysing breast screening mammograms from a single Breast Cancer Screening Unit in Madrid. The mammograms of previously vaccinated women were analysed, reviewing the axillary lymph nodes and the re-call rate secondary to axillary lymphadenopathies.

Results: Four hundred and twenty three screening mammograms were performed in May 2021 in the University Hospital Ramon y Cajal in Madrid, which is part of the Breast Screening Programme in Madrid, Spain. None of the women previously vaccinated for SARS-CoV-2 were recalled for complementary studies due to an increased in the axillary lymph nodes.

Conclusions: The protocol stablished by the Spanish Society of Breast Image that stands up for a routine breast screening mammogram after SARS-CoV-2 immunization, has no increase in the recall rate or increase in number of false positives.

目的:SARS-CoV-2免疫后常见的继发性效应是接种部位同侧腋窝淋巴结增大。最终,腋窝淋巴结的增大可能导致对乳腺筛查乳房x光检查的误解,在50至69岁之间无症状的妇女中进行早期乳腺癌诊断。本研究的目的是评估在召回率和假阳性结果数量方面接种SARS-CoV-2疫苗对乳腺筛查计划的影响。作为次要目的,我们将分析世界各地不同乳房筛查单位在接种SARS-CoV-2疫苗后采用的方案。方法:观察性和回顾性研究,分析来自马德里单一乳腺癌筛查单位的乳房筛查x线照片。我们分析了以前接种过疫苗的妇女的乳房x线照片,回顾了腋窝淋巴结和继发于腋窝淋巴结病的复发率。结果:2021年5月在马德里Ramon y Cajal大学医院进行了423次乳房x光检查,这是西班牙马德里乳房筛查计划的一部分。由于腋窝淋巴结增加,先前接种过SARS-CoV-2疫苗的妇女均未被召回进行补充研究。结论:西班牙乳腺影像学会制定的方案支持在SARS-CoV-2免疫接种后进行常规乳房筛查,没有增加召回率或假阳性数量。
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引用次数: 0
[Francisco Xavier Balmis (1753-1819) as a member of the Royal Medical Academy of Madrid.] [弗朗西斯科·泽维尔·巴尔米斯(1753-1819),马德里皇家医学院成员]
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-08-05
José Tuells
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引用次数: 0
[Risk factors related to functionality and quality of life in people over 65 years of age with hip fracture.] [与65岁以上髋部骨折患者的功能和生活质量相关的风险因素]
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-07-26
María Victoria Ruiz Romero, María Luz Calero Bernal, Ana Belén Carranza Galván, Ana Laura Blanco Taboada, Antonio Fernández Moyano, María Rocío Fernández Ojeda

Objective: Hip fracture (HF) in the elderly carries high mortality and decreases functionality and quality of life after one year. The aim of this paper was to identify risk factors that influenced functionality (Barthel) and quality of life (EQ-5D) of the elderly with osteoporotic HF.

Methods: A prospective observational study was made in people over 65 years of age with HF between October 2017 and November 2018. Clinical information was collected from the digital medical record and the scales were measured by telephone at four times: baseline, one month, six months and twelve months. Statistical analysis was made thanks to SPSS vs 25.0. Multivariate analysis was performed using a generalized linear model for repeated measures to determine the relationship of risk factors with functionality and quality of life.

Results: Functionality showed significant differences (p<0.001) between baseline measurement and one month (90 points vs 50); baseline and at twelve months (90 vs 60 points); and that of the month and at twelve months (50 points vs 60). Quality of life also presented significant differences (p<0.001) between baseline and one month (0.587 vs 0.113); and baseline and twelve months (0.220). The functionality should be in transfused and with high surgical risk (p<0.05) and the quality of life will arrive in high surgical risk (p=0.017). Those older than 85 years were the ones who recovered the least after one year, as well as patients with delirium on admission and those who received transfusions. Patients with iron therapy recovered better at six months compared to those who did not and maintained this improvement at twelve months.

Conclusions: Among the main risk factors are advanced age, male sex, transfused, high surgical risk, delirium on admission and malnutrition.

目的:老年人髋部骨折(HF)一年后死亡率高,功能和生活质量下降。本文的目的是确定影响老年骨质疏松性心衰患者功能(Barthel)和生活质量(EQ-5D)的危险因素。方法:在2017年10月至2018年11月期间,对65岁以上HF患者进行前瞻性观察研究。从数字医疗记录中收集临床信息,并通过电话分四次测量量表:基线、1个月、6个月和12个月。使用SPSS vs25.0进行统计分析。使用广义线性模型进行多变量分析,以确定危险因素与功能和生活质量的关系。结论:高龄、男性、输血、手术风险高、入院时谵妄和营养不良是两组患者的主要危险因素。
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引用次数: 0
[Quadruple aim in mHealth project to improve the control of cardiovascular risk factors in a very high-risk population.] [移动医疗项目的四重目标:提高对高危人群心血管危险因素的控制。]
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-07-22
Juan Ruiz-García, Diana Molina Villaverde

Objective: The control of cardiovascular (CV) risk factors in high-risk population is still suboptimal. This fact should make us reconsider current preventive strategies. The objective of this study was to transform the secondary cardiovascular prevention program of the University Hospital of Torrejon (Madrid, Spain), to make it more proactive, preventive, productive and efficient.

Methods: Within the quadruple aim perspective, we present a mHealth project where the patient will include, and periodically review, the parameters and values related to the main CV risk factors (smoking, diet, physical activity, weight, blood pressure, LDL cholesterol and glycosylated hemoglobin), allowing to check if therapeutic objectives recommended in the clinical practice guidelines are achieved, facilitating doctor-patient communication, and generating warnings to reinforce indications and/or intensify the therapeutic and pharmacological measures in case of non-complianc.

Results: A detailed evaluation of the achievement of quadruple aim goals will be performed. Improvements in CV risk control, experience in care, health spending and the healthcare professionals' satisfaction will be assessed.

Conclusions: mHealth offers new opportunities to improve the control of CV risk factors in high-risk patients. Better control might reduce the high cardiovascular morbidity and mortality of this population, helping to reduce health spending and improving the patients' experience and adherence to secondary prevention strategies.

目的:高危人群心血管(CV)危险因素的控制仍不够理想。这一事实应使我们重新考虑目前的预防战略。本研究的目的是改造托雷洪大学医院(西班牙马德里)的心血管二级预防项目,使其更加主动、预防性、生产性和高效率。方法:在四重目标的视角下,我们提出了一个移动健康项目,患者将包括并定期审查与主要心血管危险因素(吸烟、饮食、体育活动、体重、血压、低密度脂蛋白胆固醇和糖化血红蛋白)相关的参数和值,从而检查临床实践指南中推荐的治疗目标是否实现,促进医患沟通。并产生警告,以加强适应症和/或加强治疗和药物措施的情况下,不符合。结果:将对四项目标的实现情况进行详细的评估。将评估心血管疾病风险控制、护理经验、卫生支出和卫生保健专业人员满意度的改善情况。结论:移动医疗为改善高危患者心血管危险因素的控制提供了新的机会。更好的控制可能会降低这一人群的高心血管发病率和死亡率,有助于减少卫生支出,改善患者的体验和对二级预防策略的依从性。
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引用次数: 0
[Mental health consequences of isolation of patients with COVID-19.] [隔离COVID-19患者的心理健康后果]
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-07-21
Elena Navas, Merce López, Miguel Ángel Muñoz, Rafael Abós-Herrándiz, Claudia Gallego, Ana Tobella, Nuria Turmo, Alba Monclús, Alba Martínez, Artur Rami

Objective: The COVID-19 pandemic has had a negative effect on the mental health on the population. It is unknown if the different types of patient isolation affect them equally. The objective of the study was to determine if the effect on the psychological discomfort caused by the isolation of the population with COVID-19 in a hotel supervised by health professionals was different compared with those who were isolated at home.

Methods: Patients diagnosed with COVID-19 during the first pandemic wave in Barcelona, consecutively selected from the Primary Care lists. A telephone survey was carried out to collect information about mental health in patients who were isolated in a hotel compared to those isolated at their homes. Descriptive statistics were performed and the study variables were analyzed using mean and standard deviation, count (percentage), Chi-square test, and Student's t-test. Logistic regression models were carried out selecting frustration and anger/irritability as response variables.

Results: Of the 89 patients included, 45 (50.6%) were isolated at their homes and 44 (49.4%) at the hotel. Frustration was identified in 48.3% and irritability in 29.2% of the most patients. Most of those who presented frustration were between 45 and 65 years old, while 50% of those who felt irritability were younger. Multivariate models confirmed that patients isolated at home showed a higher risk of frustration (Odds ratio 4,12; 95% Confidence interval 1,60-11,49) and irritability (Odds ratio 3,81; 95% Confidence interval 1,32-12,10), respectively.

Conclusions: Patients isolated at home show a higher risk of presenting feelings of frustration and irritability than isolated patients in supervised hotels.

目的:新冠肺炎疫情对人群心理健康产生了负面影响。目前尚不清楚不同类型的患者隔离对他们的影响是否相同。该研究的目的是确定在卫生专业人员监督的酒店隔离COVID-19人群对心理不适的影响是否与在家中隔离的人群不同。方法:从巴塞罗那第一波大流行期间诊断为COVID-19的患者,连续从初级保健名单中选择。进行了一项电话调查,以收集在酒店隔离的患者与在家中隔离的患者的心理健康信息。进行描述性统计,并采用均数和标准差、计数(百分比)、卡方检验和学生t检验对研究变量进行分析。选择挫折和愤怒/易怒为反应变量,建立Logistic回归模型。结果:89例患者中,家中隔离45例(50.6%),酒店隔离44例(49.4%)。48.3%的患者有挫败感,29.2%的患者有易怒感。大多数表现出挫败感的人年龄在45岁到65岁之间,而50%感到烦躁的人更年轻。多变量模型证实,在家隔离的患者表现出更高的沮丧风险(优势比4,12;95%可信区间1,60-11,49)和易怒(优势比3,81;95%置信区间分别为1,32-12,10)。结论:在家隔离的患者比在监管的酒店隔离的患者表现出更高的沮丧感和烦躁感。
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引用次数: 0
[When it will be possible the interdisciplinary dialogue about the management of the COVID-19 syndemic?] [关于COVID-19综合征管理的跨学科对话何时可能?]
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-07-12
Constanza Jacques-Aviñó, Israel Rodríguez Giralt, Marisol E Ruiz, Laura Medina-Perucha, Maria Sol Anigstein, Anna Berenguera

Since countries and their institutions began to feel overwhelmed by COVID-19, it has not been surprising to hear the complaints, ailments and discomforts of millions of people who have experienced significant emotional and material losses. It has been a cluster of factors that have been crossed by biological, socioeconomic and cultural phenomena, interconnected with each other, and that have become structural. Despite the broad contribution of the scientific field to the study of this phenomenon, the different disciplines in general, and those from the Social Sciences in particular, have had little participation and opportunities for communication and research. A good indicator to assess the priorities regarding the generation of knowledge is to observe the number of relevant publications and total citations, among which biomedical ones stand out . This invites a tremendously necessary debate since, considering the complexity of the phenomenon, we wonder why it has not been proportional to the collaboration of the different disciplines when considering its approach.

自从各国及其机构开始感到被COVID-19压垮以来,听到数百万人的抱怨、疾病和不适就不足为奇了,他们经历了重大的情感和物质损失。它是一组因素,这些因素被生物、社会经济和文化现象交叉,相互联系,并已成为结构性因素。尽管科学领域对这一现象的研究做出了广泛的贡献,但一般来说,不同学科,特别是社会科学学科,很少参与,也很少有机会进行交流和研究。观察相关出版物的数量和总引用量是评估知识生成优先级的一个很好的指标,其中生物医学方面的出版物尤为突出。这引起了一场非常必要的辩论,因为考虑到这一现象的复杂性,我们想知道为什么在考虑其方法时,它与不同学科的合作不成比例。
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引用次数: 0
[Analysis of the efficiency of hospitals in Castilla y León (Spain)]. [卡斯蒂利亚医院效率分析León(西班牙)]。
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-07-05
Carlos Cabezas Pascual, Alberto Pérez-Rubio, Jose María Eiros Bouza

Objective: The analysis of efficiency represents an area of growing interest in the field of public management. Hospital efficiency depends mainly on the use that the institution makes of its resources and their cost. The importance of hospital efficiency studies is justified by the fact that health spending is the second most important item of public spending. The objective of the present study focused on the analysis of the degree of efficiency with which the public hospitals of Castilla y León were managed.

Methods: The scope of the research was limited to the 14 hospitals of the Public Health Service of Castilla y León (Sacyl), taking the five-year period 2014-2018 as the study period. For the analysis, the non-parametric technique of Data Envelopment Analysis (DEA) was used. Both constant returns to scale (CRS) and variable returns to scale (VRS) have been used, calculating the global technical efficiency, pure technical efficiency and scale efficiency for each health institution.

Results: The grouped results showed that the global technical efficiency (GTE) had reached an average of 92.02%, the pure technical efficiency (PTE) 94.10% and the scale efficiency (EE) 97.74%.

Conclusions: The DEA is presented as a valid technique for analyzing the efficiency of hospitals, with the efficiency of all groups of hospitals (groups I, III and IV) being very similar in terms of PTE, around 97%, with the exception of group II hospitals that are the least efficient.

目的:效率分析是公共管理领域中一个日益引起人们兴趣的领域。医院的效率主要取决于机构对其资源的利用及其成本。医疗支出是公共支出中第二重要的项目,这一事实证明了医院效率研究的重要性。本研究的目的是分析卡斯蒂利亚León公立医院的管理效率。方法:研究范围限于卡斯蒂利亚León (Sacyl)公共卫生服务的14家医院,以2014-2018年5年为研究期。分析采用数据包络分析(DEA)的非参数技术。采用恒定规模收益(CRS)和可变规模收益(VRS)两种方法,分别计算各卫生机构的全球技术效率、纯技术效率和规模效率。结果:分组结果显示,整体技术效率(GTE)平均达到92.02%,纯技术效率(PTE)平均达到94.10%,规模效率(EE)平均达到97.74%。结论:DEA是一种有效的分析医院效率的技术,所有医院组(I、III和IV组)的效率在PTE方面非常相似,约为97%,除了效率最低的II组医院。
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引用次数: 0
[Study protocol: A strategy for deprescribing statins and ezetimibe in primary prevention of cardiovascular disease in patients older than 75 years: health outcomes analysis.] [研究方案:他汀类药物和依折麦布在75岁以上患者心血管疾病一级预防中的应用策略:健康结果分析]
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-06-29
Natalia Alzueta Istúriz, Julen Fernández González, Amaya Echeverría Gorriti, Patricia García González, Lorea Sanz Álvarez, Mª Concepción Celaya Lecea, Oihane Goñi Zamarbide, Mª Teresa Acín Gericó, Rafael Bartolomé Resano, Javier Garjón Parra

Objective: The benefit-risk balance of statins and ezetimibe as primary prevention of cardiovascular disease is controversial in elderly patients due to the doubts about their effectiveness and certainty about adverse effects. The aim of this paper was to analyze health outcomes of a statin and ezetimibe deprescription strategy in patients aged 75 or older treated with these drugs for primary prevention of cardiovascular disease.

Methods: An observational ambispective cohort study was made to evaluate health outcomes after the implementation of a strategy for deprescribing statins and ezetimibe in patients aged 75 or older who take these drugs for primary prevention of cardiovascular disease. To avoid the risk of bias due to non-random assignment of patients to different groups, a propensity score will be calculated for each patient using logistic regression. The outcome of interest will be the deprescription or not of statins or ezetimibe. Time to hospital admission or death from any cause and other variables related to health outcomes will be analysed. Groups with and without statin or ezetimibe deprescription will be compared by survival analysis using Cox regression to estimate the hazard ratio.

Conclusions: It is expected to obtain health outcomes of the strategy of deprescribing statins and ezetimibe in primary prevention in patients aged 75 or older. They will provide information on the advisability of continuing the strategy.

目的:他汀类药物和依折替贝作为老年患者心血管疾病一级预防的利弊平衡存在争议,因为对其有效性存在疑问,对不良反应存在确定性。本论文的目的是分析75岁及以上患者使用他汀类药物和依折替贝去处方策略用于心血管疾病一级预防的健康结果。方法:一项观察性双视角队列研究,评估75岁及以上服用他汀类药物和依折替米布进行心血管疾病一级预防的患者在实施该策略后的健康结果。为了避免因患者非随机分配到不同组而产生的偏倚风险,将使用逻辑回归计算每个患者的倾向评分。感兴趣的结果将是他汀类药物或依折可布的停用或禁用。将分析入院时间或任何原因导致的死亡以及与健康结果相关的其他变量。有和没有他汀或依折麦布去处方组将通过生存分析进行比较,使用Cox回归来估计风险比。结论:在75岁及以上患者的一级预防中,他汀类药物和依折麦布联合应用可获得预期的健康结果。他们将提供关于继续该战略是否可取的信息。
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引用次数: 0
[Descriptive analysis of triggers, outcomes and the response of the health systems of child drowning in Galicia (Spain). A 17-year retrospective study.] [对加利西亚(西班牙)儿童溺水的触发因素、结果和卫生系统应对措施的描述性分析]。一项为期17年的回顾性研究。
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-06-22
Patricia Sánchez-Lloria, Roberto Barcala-Furelos, Martín Otero-Agra, Silvia Aranda-García, Óscar Cosido-Cobos, Jorge Blanco-Prieto, Ignacio Muñoz-Barús, Antonio Rodríguez-Núñez

Objective: Drowning is one of major public health problem in childhood. The aim of this paper was to describe the characteristics, locations, interventions and outcomes of child drowning in Galicia over 17 years.

Methods: Retrospective study of 100% of data of drowning amongst children aged 0-14 in the 2004-2020 period who were attended by the 061 emergency services in Galicia (Spain) was made. The characteristics of the incident, the victim's profile, location, type of medical care given and whether the victim survived or died were analysed using the Chi Square test to compare relative frequencies, and Odds Ratio to estimate the risk.

Results: During the period under study, 100 child drownings were recorded. In 55%, the main cause was lack of supervision. Young children (aged 0-4) primarily drowned in pools, and pre-teens and teenagers (aged 10-14) in the sea. In 42% of the incidents, bystanders performed CPR (37% included ventilation). Emergency services took 12 minutes on average to arrive at the scene. 6% died in situ and of the rest, were taken to hospital and admitted in 47% PICU, 26% ward, 8% discharged from Accident and Emergency (43% with pulmonary oedema, 41% with supplemental oxygen, 13% with IMV/NIMV [invasive mechanical ventilation/non-invasive]). Pneumonia was the most common complication and survival to discharge was 77%.

Conclusions: Small children usually drown in pools and water facilities because of lack of supervision, whereas adolescents usually drown in the sea. CPR started by bystanders and the fast response of emergency services contributed to a high rate of survival. A large amount of data was lost during the process: accurate, standardized coding of drowning is necessary.

目的:溺水是儿童主要公共卫生问题之一。本文的目的是描述的特点,地点,干预措施和结果的儿童溺水在加利西亚超过17年。方法:回顾性研究2004-2020年期间在加利西亚(西班牙)061急救中心就诊的0-14岁儿童中100%的溺水数据。使用卡方检验来比较相对频率,并使用优势比来估计风险,分析了事件的特征、受害者的概况、地点、所提供的医疗护理类型以及受害者是否存活或死亡。结果:在研究期间,记录了100名儿童溺水事件。55%的人认为主要原因是缺乏监管。幼儿(0-4岁)主要在游泳池中溺水,青少年和青少年(10-14岁)在海里溺水。在42%的事故中,旁观者进行了心肺复苏术(37%包括通气)。紧急救援人员平均需要12分钟才能到达现场。6%的患者当场死亡,其余的患者送往医院,47%的患者住在PICU, 26%的患者住在病房,8%的患者从急症室出院(43%的患者患有肺水肿,41%的患者接受了补充氧气,13%的患者接受了IMV/NIMV[有创机械通气/无创通气])。肺炎是最常见的并发症,出院存活率为77%。结论:由于缺乏监管,幼儿溺水多发生在水池和水上设施,而青少年溺水多发生在海里。由旁观者开始的心肺复苏术和紧急服务的快速反应有助于提高生存率。在这个过程中,大量的数据丢失了:准确、标准化的溺水编码是必要的。
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引用次数: 0
[Lean Six Sigma in the implementation of automated dispensing systems: improving the safe use of medications in thoracic surgery.] [精益六西格玛在自动配药系统的实施:提高胸外科药物的安全使用]
IF 1.1 4区 医学 Q2 Medicine Pub Date : 2022-04-12
Siria Pablos Bravo, José Manuel Caro Teller, Candelas López-López, Ana María Carro Ruiz, Ana María Guede González, José Miguel Ferrari Piquero

Objective: Medications errors are a major problem that can cause a harm to inpatients. The main objective of the study was to compared medication errors in pharmacotherapeutic process before and after to carried out an intervention: to implant an automated dispensing cabine with to use Lean Six Sigma methodology. The secondary objective was to assess process performance, sigma level and defects per one million opportunities for medication error.

Methods: Quasi-experimental and randomized study carried out in a Thoracic Surgery Unit of a Spanish Hospital. A pharmaceutic recorded and assesed the medication errors detected during pre-intervention period (july-august 2017) and post-intervention period (march-april 2018). The steps analyzed were dispensing, storage and compounding/administration. The pharmacist observed a third of the medication dispensed, stored and compounded/administered during the study period. The observed medication was randomly selected using AleatorMetod.xls software. To perform the statistical analysis, Student's t test and Mann-Whitney U test were used to compare quantitative variables, and Chi-square test for qualitative variables. A significance level of p<0.05 was considered.

Results: The pharmaceutic recorded 4,538 drugs. After intervention, medication errors were decreased a 49% in total pharmacotherapeutic process (12.06% vs 6.15%; p<0.001). In addition, errors were decreased a 91.6% (4.27% vs 0.36%; p=0.004) in the step of medication storage; and a 75.8% (22.52% vs 5.46%; p<0.001) in the step of drugs compounding/administration. However, medication errors were increased in the step of medication dispensing (4.51% vs 15.29%; p<0.001). The process performance increased a 6% (87.9% vs 93.9%), sigma level increased from 2.67 to 3.04 and defects per one million opportunities for medication error decreased a 49%.

Conclusions: To implant an automated dispensing cabinet with Lean Six Sigma methodology helps create a safer environment for the inpatient, reducing medication errors in the steps of storage and preparation/administration, as well as improving the total process performance and sigma level.

目的:用药差错是对住院患者造成伤害的主要问题之一。本研究的主要目的是比较药物治疗过程中的用药错误,在进行干预之前和之后:植入自动配药柜,使用精益六西格玛方法。次要目标是评估过程性能、西格玛水平和每百万分之一次用药错误机会的缺陷。方法:在西班牙某医院胸外科进行准实验和随机研究。A药房记录并评估了干预前(2017年7月- 8月)和干预后(2018年3月- 4月)发现的用药错误。分析的步骤是配药、储存和配药/给药。药剂师在研究期间观察了三分之一的药物分配、储存和配制/施用。采用aleatormethod .xls软件随机抽取观察用药。进行统计分析时,定量变量比较采用Student’st检验和Mann-Whitney U检验,定性变量比较采用卡方检验。结果具有显著性水平:共记录药品4538种。干预后,整个药物治疗过程中的用药错误减少了49% (12.06% vs 6.15%;结论:采用精益六西格玛方法植入自动配药柜有助于为住院患者创造更安全的环境,减少储存和制备/给药环节的用药错误,提高整个过程的绩效和西格玛水平。
{"title":"[Lean Six Sigma in the implementation of automated dispensing systems: improving the safe use of medications in thoracic surgery.]","authors":"Siria Pablos Bravo,&nbsp;José Manuel Caro Teller,&nbsp;Candelas López-López,&nbsp;Ana María Carro Ruiz,&nbsp;Ana María Guede González,&nbsp;José Miguel Ferrari Piquero","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Medications errors are a major problem that can cause a harm to inpatients. The main objective of the study was to compared medication errors in pharmacotherapeutic process before and after to carried out an intervention: to implant an automated dispensing cabine with to use Lean Six Sigma methodology. The secondary objective was to assess process performance, sigma level and defects per one million opportunities for medication error.</p><p><strong>Methods: </strong>Quasi-experimental and randomized study carried out in a Thoracic Surgery Unit of a Spanish Hospital. A pharmaceutic recorded and assesed the medication errors detected during pre-intervention period (july-august 2017) and post-intervention period (march-april 2018). The steps analyzed were dispensing, storage and compounding/administration. The pharmacist observed a third of the medication dispensed, stored and compounded/administered during the study period. The observed medication was randomly selected using AleatorMetod.xls software. To perform the statistical analysis, Student's t test and Mann-Whitney U test were used to compare quantitative variables, and Chi-square test for qualitative variables. A significance level of p<0.05 was considered.</p><p><strong>Results: </strong>The pharmaceutic recorded 4,538 drugs. After intervention, medication errors were decreased a 49% in total pharmacotherapeutic process (12.06% vs 6.15%; p<0.001). In addition, errors were decreased a 91.6% (4.27% vs 0.36%; p=0.004) in the step of medication storage; and a 75.8% (22.52% vs 5.46%; p<0.001) in the step of drugs compounding/administration. However, medication errors were increased in the step of medication dispensing (4.51% vs 15.29%; p<0.001). The process performance increased a 6% (87.9% vs 93.9%), sigma level increased from 2.67 to 3.04 and defects per one million opportunities for medication error decreased a 49%.</p><p><strong>Conclusions: </strong>To implant an automated dispensing cabinet with Lean Six Sigma methodology helps create a safer environment for the inpatient, reducing medication errors in the steps of storage and preparation/administration, as well as improving the total process performance and sigma level.</p>","PeriodicalId":47152,"journal":{"name":"Revista Espanola De Salud Publica","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10502923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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