Oral and Maxillofacial Surgery-Heidelberg最新文献

Purpose: X, formerly known as Twitter, is a popular social media platform that facilitates oral and maxillofacial surgeons to disseminate a wide array of information to a global audience. The purpose of this study is to identify the top influencers in oral and maxillofacial surgery on X, characterize who they are, and relate their social media influence to academic influence.

Methods: We utilized the "BuzzSumo" Application Programming Interface to identify the most followed accounts for the topic search "oral and maxillofacial surgery." A secondary calculator from the Mention API was used to assign a numerical score of "influence" based on their algorithm. The top 100 accounts associated with the highest engagement scores were characterized by name, status as an oral and maxillofacial surgeon/organization, location, and academic h-index.

Results: We found that 52/100 (52%) of users/organizations were oral and maxillofacial surgeons/residents. There was no significant correlation between the h-index and the X engagement score, R² = 0.8316 (P = 0.088). In comparison, other specialties have a higher percentage of practitioners using X and have found a correlation between h-index and X engagement score.

Conclusion: Our results indicate there is a demonstrated need for the creation of more educational content from high-ranking academic sources.

Purpose: To evaluate and compare, using finite elements three-dimensional (3D) analysis, two techniques of stable internal fixation in 2 patterns of sagittal split ramus osteotomy (SSRO) and the repercussions of occlusal load distribution in the postoperative period.

Methods: A 3D finite element model of a hemimandible was created. The models were divided into 2 split patterns of SSRO advanced 5 mm forward, a split pattern (1) following the Epker osteotomy design and another split pattern (2) following Posnick osteotomy design, simulated by CAD (Computer Aided Engineering) Rhinoceros 3D^®. Two internal fixation techniques were simulated by HyperMesh: A- one titanium miniplate of the Arnett system (1 mm) for orthognathic surgery fixed with four monocortical screws; B- one titanium plate fixed with four monocortical screws and one bicortical screw. Resistance, stress and displacement were analyzed applying a 200 N vertical load to the occlusal surface region of the mandibular first molar and a 100 N to the incisal surface of the mandibular central incisor.

Results: The results were presented through the von Mises stress analysis. A difference in the displacement of the models fixed with only one miniplate and four monocortical screws was observed. The models with split pattern (2) presented smaller displacements when compared to the split pattern (1). For metallic components, the split pattern (2) exhibits lower strain values, although it has no significant difference.

Conclusion: The fixation technique B proved to be more rigid and lower stress values both in the bone and in the plate, as well as lower deformation and displacements were shown in comparison to fixation technique A for all mandibular movements and forces.

Aim: In recent years, stereotactic ablative radiotherapy (SABR) has been created. Using one or a small number of dosage fractions, SABR enables the hypofractionated treatment of extracranial tumours, delivering a high biologically effective dose with little damage. This review article explores role of stereotactic ablative radiotherapy in head neck cancers.

Material methods: Using the search parameters SABR, stereotactic radiotherapy, and targeted radiation, the publications were found on PubMed and Scopus. For this review, the closest publications to SABR were consulted from the search results that were returned.

Conclusion: In the treatment of patients with recurring and/or previously irradiated head and neck malignancies, SABR is technically possible, well-tolerated, and performs comparably to other salvage therapy options. It also offers the benefit of a quicker course of therapy. Timetable, increased adherence, and secure delivery in the outpatient context. This presents a chance to provide SABR as a therapy option for a limited number of patients. In order to properly administer a highly conformal ablative dosage to targets (or tumours) in the body, SBRT requires sophisticated technologies in radiation planning and imaging guiding. Because of its highly conformal dose distributions and stereotactic spatial precision in administration, SABR is being employed more and more to treat a range of head and neck tumours.

Purpose: This observational, cross-sectional study evaluated healthy Caucasian Brazilian individuals' normal lip dimensions according to sex and age (20-50 years) using stereophotogrammetry.

Methods: A total of 130 individuals divided into four groups according to sex and age were analyzed using stereophotogrammetry. Ten linear lip, five angular lip, and three lip surface measurements (upper, lower, and total lip vermilion) were obtained. Comparisons were performed using two-way ANOVA.

Results: Mouth width, philtrum width, and lower lip cutaneous height were significantly greater in men than women. The upper lip height, upper lip cutaneous height, and average lower vermilion lip angle were significantly larger in men than women and increased with age (group), with medium or large effect sizes. A sex × group interaction was present for total vermilion height, upper vermilion height, total lip height, lower lip height, average upper vermilion lip angle, average Cupid's bow angle, mentolabial angle, and upper and total vermilion lip areas. When factors interact (sex/group), one affects the outcome of the other.

Conclusions: Relevant linear lip measures were greater in men than women and increased with age in a mixed population from 20 to 50 years old. Thus, the lip and mouth are severly impacted by aging.

Purpose: The bizarre parosteal osteochondromatous proliferation (bpop) is a rare lesion that affects long tubular bones of the feet and hands. Since these lesions are even rarer in the jaws, this systematic review aimed to summarize the up-to-date scientific evidence that can guide health professionals on the diagnosis and treatment of bpop in the jaws.

Methods: This prisma-guided and prospero-registered (crd42024524576) review included case reports with confirmed anatomopathological diagnosis of bpop. The articles were searched in november 2024 in the pubmed, scopus, web of science, scielo, cochrane library, embase, and livivo databases and the academic repositories (proquest, open grey, ibict/bdt, and google scholar) without language or publication date restrictions.

Results: Twelve cases of patients aged between 2 and 72 years (mean 26.5 ± 19.8 years) with equal gender distribution were included. Most lesions were clinically described as nodules or swellings (83.5%), asymptomatic (58.3%), with a mean diameter of 15.8 ± 16.2 mm, located in the mandible (58.3%) and anterior region of the jaws (75%). Radiographically, 66.7% of the lesions had well-defined borders and 91.7% were in continuity with the cortical bone. Histopathological findings revealed pleomorphic chondrocytes (83.3%), hypercellular cartilage (83.3%), and 'blue bone' (50%). All bpop lesions were surgically excised and recurrence was observed in 41.7% of cases with a mean follow-up of 8.8 months.

Conclusion: Since bpop demonstrates a recurrent behavior, further investigations with long-term follow-up periods are needed to address its malignancy potential.

Objective: To assess the currently applied regimens of antithrombotic therapy after microvascular reconstruction.

Methods: A systematic literature review was performed using the MEDLINE/PubMed Database for work published until September 2022. Data synthesis and risk of bias were reported in accordance with NIH Study Quality Assessment Tools guidelines.

Results: 204 articles were found including the keywords either in the abstract or in the title. After screening their abstracts and titles, 41 articles were identified as suitable and the full texts were retrieved. 23 studies were included in this review. No gold standard could be shown; on the contrary, the applied antithrombotic regimens varied widely. A broad consensus could be obtained that Dextran should no longer be used after an increased complication rate was proven. The most commonly used agents are unfractionated (UFH) as well as low molecular weight (LMWH) heparin and acetylsalecylic acid (ASA), although the literature results are partly contradictory.

Conclusions: A consensus could be found that it is useful to perform thromboprophylaxis when the patient is immobilized, but there is no evidence for a survival advantage of the flap by chemical prophylaxis. On the contrary, it has been shown that there is an increased rate of bleeding complications and flap loss combined with the simultaneous use of multiple chemical anticoagulants. In conclusion the generalized use of anticoagulation is explained less by microvascular grafting than by general medical risk factors. Thus, large prospective RCTs will be needed to establish a gold standard therapeutic regimen.

Purpose: The aim of this study was to evaluate the alveolar repair process in rats exposed to nicotine after tooth extraction, using ozonised water and low-power laser therapy (LPLT) as therapeutic adjuvants.

Materials and methods: Thirty wistar rats (Rattus Norvegicus) were used and given the nicotine solution via subcutaneous tissue. After 7 days, the upper right central incisor was surgically extracted. Three days after the surgical procedure, the animals continued to receive nicotine until the day of euthanasia, totalling 21 days after extraction.

Results: The result was that the groups that received coadjuvant therapy had neoformed mature bone, unlike the group that did not receive it.

Conclusions: Based on the literature and the results obtained, we can conclude that nicotine negatively influenced the healing process and bone repair in the alveoli; however, the use of ozonised water and LPLT, even in the presence of nicotine, was effective, as it enhanced the repair process, making them good options for surgical procedures in patients who smoke.

Introduction: Oral potentially malignant disorders impact the oral mucosa and elevate the risk of oral cancer. In India, the high prevalence of oral submucous fibrosis and leukoplakia is attributed to habits such as tobacco use and smoking. Plasminogen activator inhibitor-1 plays a crucial role in cancer progression. Single-nucleotide polymorphisms are the most widespread genetic variations associated with various diseases, including cancers.

Aim: This study aimed to investigate the association between PAI-1 promoter rs2227631 (- 844G > A) and missense variant rs6092 (+ 43G > A) polymorphisms and the susceptibility to OSMF and leukoplakia in a South Indian cohort of chewers and smokers.

Methods: The rs2227631 and rs6092 of PAI-1 were analysed using PCR- RFLP in 285 subjects including OSMF, leukoplakia and healthy controls, along with their habitual factors. The allele frequencies and genotypic associations were examined. The impact of these SNPs on mRNA secondary structure, gene-gene and protein-protein interactions was also analysed using in silico tools.

Results: The habits of chewers and smokers were (79% and 72%) in OSMF and (62% and 75%) in leukoplakia and disease prevalent was (78% and 59%) males and (22% and 26%) females respectively. The G allele of rs2227631 and A allele of rs6092 were significantly associated with the diseases (P < 0.05).

Conclusion: PAI-1 polymorphisms rs2227631 and rs6092 were associated with OSMF and leukoplakia of the south Indian cohort.

Objective: The study aimed to compare and analyze the in vitro mechanical behavior of vertical load on three different sagittal split osteotomy designs proposed by Epker, Wolford, and Wyatt, focusing on the implications of each design on mandibular stability.

Study design: Synthetic polyurethane hemi-mandibular models were used to replicate the osteotomies according to the designs suggested by Epker, Wolford, and Wyatt. Each model group was subjected to linear vertical loading until system failure, with peak load and deformation recorded. The study utilized a controlled sample preparation and loading test to ensure standardization across all groups. Analysis of variance (ANOVA) and the Tukey test were applied to compare the mechanical responses among the different osteotomy designs.

Results: The findings indicated no significant difference in displacement and vertical loading resistance between Groups 1 and 2; however, differences were found in Group 3 (Wyatt), where increased mandibular fragility was observed when screws were placed in thinner bone areas. Statistical analysis showed that the modifications in the osteotomy design led to significant differences in mechanical behavior, particularly in Group 3, highlighting the importance of bone thickness and osteotomy technique on postoperative early stability and mechanical stress distribution.

Conclusions: The study concludes that the choice of sagittal split osteotomy design significantly impacts the mechanical behavior under vertical loading, with particular emphasis on the importance of bone thickness at fixation points and the technique used. The findings suggest a preference for the modification proposed in group 1 and 2 in cases where increased mandibular stability and minimized postoperative complications are desired.