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Unshared Minds, Decaying Worlds: Towards a Pathology of Chronic Loneliness. 不共享的思想,衰败的世界:迈向慢性孤独病理学》(Unshared Minds, Decaying Worlds: Towards a Pathology of Chronic Loneliness)。
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2024-07-11 DOI: 10.1093/jmp/jhae020
Ian Marcus Corbin, Amar Dhand

The moment when a person's actual relationships fall short of desired relationships is commonly identified as the etiological moment of chronic loneliness, which can lead to physical and psychological effects like depression, worse recovery from illness and increased mortality. But, this etiology fails to explain the nature and severe impact of loneliness. Here, we use philosophical analysis and neuroscience to show that human beings develop and maintain our world-picture (our sense of what is true, important, and good) through joint attention and action, motivated by friendship, in the Aristotelian sense of "other selves" who share a sense of the true and the good, and desire the good for each other as much as for themselves. The true etiological event of loneliness is the moment one's world-picture becomes unshared. The pathogenesis is a resultant decay of our world-picture, with brain and behavior changes following as sequelae.

当一个人的实际人际关系与期望的人际关系相差甚远时,通常被认为是慢性孤独的病因时刻,它会导致抑郁、疾病恢复更差和死亡率上升等生理和心理影响。但是,这种病因学无法解释孤独的本质和严重影响。在这里,我们通过哲学分析和神经科学来说明,人类是在友谊的驱使下,通过共同的关注和行动来发展和维护我们的世界图景(我们对什么是真、什么是重要、什么是好)的。孤独的真正病因是一个人的世界图景变得不可共享。其发病机理是我们的世界图景随之衰落,大脑和行为也随之发生变化,成为后遗症。
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引用次数: 0
What We Argue About When We Argue About Death. 当我们争论死亡时,我们在争论什么?
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2024-07-11 DOI: 10.1093/jmp/jhae016
Sean Aas

The literature on the determination of death has often if not always assumed that the concept of human death should be defined in terms of the end of the human organism. I argue that this broadly biological conceptualization of human death cannot constitute a basis for agreement in a pluralistic society characterized by a variety of reasonable views on the nature of our existence as embodied beings. Rather, following Robert Veatch, I suggest that we must define death in moralized terms, as the loss of an especially significant sort of moral standing. Departing from Veatch, however, I argue that we should not understand death in terms of the loss of all moral status whatsoever. Rather, I argue, what we should argue about, when we argue about death, is when and why people lose their rights-claims to the protection and promotion of their basic bodily functioning.

关于确定死亡的文献经常甚至总是假定,人类死亡的概念应从人类机体终结的角度来定义。我认为,这种对人类死亡的广义生物学概念化并不能构成在一个多元化社会中达成一致的基础,因为在这个社会中,人们对我们作为具身存在的本质有着各种合理的看法。相反,继罗伯特-维奇(Robert Veatch)之后,我建议我们必须用道德化的术语来定义死亡,将其视为一种特别重要的道德地位的丧失。然而,与维奇不同的是,我认为我们不应该从丧失所有道德地位的角度来理解死亡。相反,我认为,当我们争论死亡问题时,我们应该争论的是人们何时以及为何丧失了他们的权利--对保护和促进其基本身体机能的权利要求。
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引用次数: 0
Genetic Enhancement, Human Rights, and Regioglobal Bioethics. 基因强化、人权和全球生物伦理学。
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2024-07-03 DOI: 10.1093/jmp/jhae029
Ruiping Fan

This article examines the cross-cultural bioethical concerns stemming from the potential use of CRISPR-Cas9 for genetic enhancement projects. It emphasizes the need to differentiate between basic and non-basic human rights when considering genetic enhancement, as recent international declarations lack this distinction. Basic rights possess a universal nature and are applicable across cultures, while non-basic rights are culturally specific and should be determined within respective regions. To illustrate this, the study explores the acceptance or rejection of non-basic rights related to genetic enhancement in two distinct cultural categories: Type-A and Type-B cultures. Type-A cultures predominantly adhere to a liberal moral framework, while Type-B cultures are rooted in Confucian morality. Additionally, the article argues for two basic rights in genetic enhancement: the right to be free from bodily harm and the right to be free from deception. These rights differ from non-basic rights and should be universally upheld in all cultures. By analyzing a hypothetical case and drawing parallels with the He Jiankui incident, the article investigates the violation of these two basic rights in each scenario, regardless of cultural context. Consequently, both cases should be unequivocally rejected in both Type-A and Type-B cultures.

本文探讨了可能使用 CRISPR-Cas9 进行基因强化项目所引发的跨文化生物伦理问题。文章强调,在考虑基因强化问题时,有必要区分基本人权和非基本人权,因为近期的国际宣言缺乏这种区分。基本权利具有普遍性,适用于各种文化,而非基本权利则具有文化特殊性,应在各地区内确定。为了说明这一点,本研究探讨了两个不同文化类别对与基因强化有关的非基本权利的接受或拒绝:A 类文化和 B 类文化。A 型文化主要遵循自由道德框架,而 B 型文化则植根于儒家道德。此外,文章还论证了基因强化中的两项基本权利:不受身体伤害的权利和不受欺骗的权利。这些权利与非基本权利不同,应在所有文化中得到普遍维护。文章通过分析一个假设的案例,并将其与贺建奎事件相比较,探讨了这两项基本权利在不同文化背景下受到侵犯的情况。因此,无论在 A 型文化还是 B 型文化中,这两种情况都应被明确拒绝。
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引用次数: 0
The Dynamics of Disease: Toward a Processual Theory of Health. 疾病的动态:迈向健康过程理论》。
IF 1.6 3区 哲学 Q3 ETHICS Pub Date : 2024-04-20 DOI: 10.1093/jmp/jhae014
Thor Hennelund Nielsen

The following article presents preliminary reflections on a processual theory of health and disease. It does this by steering the discussion more toward an ontology of organisms rather than conceptual analysis of the semantic content of the terms "health" and "disease." In the first section, four meta-theoretical assumptions of the traditional debate are identified and alternative approaches to the problems are presented. Afterwards, the view that health and disease are constituted by a dynamic relation between demands imposed on an organism and individual presuppositions for adequate response is developed. In the last section, the paper takes stock of three possible objections to and clarifies some implications of this approach to the notions of health and disease.

以下文章对健康与疾病的过程性理论进行了初步思考。文章将讨论更多地引向有机体本体论,而不是对 "健康 "和 "疾病 "这两个术语的语义内容进行概念分析。在第一节中,作者指出了传统辩论中的四个元理论假设,并提出了解决这些问题的替代方法。随后,论文提出了健康和疾病是由强加给有机体的要求与个人做出适当反应的前提条件之间的动态关系构成的观点。在最后一节中,本文总结了三种可能的反对意见,并阐明了这种方法对健康和疾病概念的一些影响。
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引用次数: 0
The Social Epistemology of Clinical Placebos. 临床安慰剂的社会认识论》。
IF 1.6 3区 哲学 Q3 ETHICS Pub Date : 2024-04-20 DOI: 10.1093/jmp/jhae010
Melissa Rees

Many extant theories of placebo focus on their causal structure wherein placebo effects are those that originate from select features of the therapy (e.g., client expectations or "incidental" features like size and shape). Although such accounts can distinguish placebos from standard medical treatments, they cannot distinguish placebos from everyday occurrences, for example, when positive feedback improves our performance on a task. Providing a social-epistemological account of a treatment context can rule out such occurrences, and furthermore reveal a new way to distinguish clinical placebos from standard medical treatments.

许多现存的安慰剂理论都将重点放在其因果结构上,即安慰剂效应源于疗法的特定特征(如客户期望或大小和形状等 "偶然 "特征)。虽然这种说法可以将安慰剂与标准医疗区分开来,但却无法将安慰剂与日常现象区分开来,例如,当积极反馈提高了我们的任务绩效时。对治疗环境进行社会认识论解释可以排除此类情况的发生,并进一步揭示了区分临床安慰剂和标准医疗的新方法。
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引用次数: 0
A Fictionalist Account of Open-Label Placebo. 关于开放标签安慰剂的虚构故事
IF 1.6 3区 哲学 Q3 ETHICS Pub Date : 2024-04-20 DOI: 10.1093/jmp/jhae008
Doug Hardman

The placebo effect is now generally defined widely as an individual's response to the psychosocial context of a clinical treatment, as distinct from the treatment's characteristic physiological effects. Some researchers, however, argue that such a wide definition leads to confusion and misleading implications. In response, they propose a narrow definition restricted to the therapeutic effects of deliberate placebo treatments. Within the framework of modern medicine, such a scope currently leaves one viable placebo treatment paradigm: the non-deceptive and non-concealed administration of "placebo pills" or open-label placebo (OLP) treatment. In this paper, I consider how the placebo effect occurs in OLP. I argue that a traditional, belief-based account of OLP is paradoxical. Instead, I propose an account based on the non-doxastic attitude of pretence, understood within a fictionalist framework.

安慰剂效应现在一般被广泛定义为个人对临床治疗的社会心理背景的反应,有别于治疗的生理效应特征。然而,一些研究人员认为,这种宽泛的定义会导致混淆和误导。对此,他们提出了一个狭义的定义,仅限于蓄意安慰剂治疗的疗效。在现代医学的框架内,这样的范围目前只剩下一种可行的安慰剂治疗范例:非欺骗性和非隐蔽性地服用 "安慰剂药片 "或开放标签安慰剂(OLP)治疗。在本文中,我将探讨安慰剂效应是如何在 OLP 中产生的。我认为,传统的、基于信念的 OLP 解释是自相矛盾的。相反,我提出了一种基于非悖论的伪装态度的解释,在虚构主义的框架内加以理解。
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引用次数: 0
Three Arguments Against Institutional Conscientious Objection, and Why They Are (Metaphysically) Unconvincing. 反对制度性良心反对的三个论点,以及为什么它们(从形而上学角度)无法令人信服。
IF 1.6 3区 哲学 Q3 ETHICS Pub Date : 2024-04-20 DOI: 10.1093/jmp/jhae012
Xavier Symons, Reginald Mary Chua

The past decade has seen a burgeoning of scholarly interest in conscientious objection in healthcare. While the literature to date has focused primarily on individual healthcare practitioners who object to participation in morally controversial procedures, in this article we consider a different albeit related issue, namely, whether publicly funded healthcare institutions should be required to provide morally controversial services such as abortions, emergency contraception, voluntary sterilizations, and voluntary euthanasia. Substantive debates about institutional responsibility have remained largely at the level of first-order ethical debate over medical practices which institutions have refused to offer; in this article, we argue that more fundamental questions about the metaphysics of institutions provide a neglected avenue for understanding the basis of institutional conscientious objection. To do so, we articulate a metaphysical model of institutional conscience, and consider three well-known arguments for undermining institutional conscientious objection in light of this model. We show how our metaphysical analysis of institutions creates difficulties for justifying sanctions on institutions that conscientiously object. Thus, we argue, questions about the metaphysics of institutions are deserving of serious attention from both critics and defenders of institutional conscientious objection.

在过去的十年中,学术界对医疗保健领域依良心拒服兵役的兴趣日益浓厚。迄今为止,相关文献主要关注的是反对参与有道德争议程序的医疗从业者个人,而在本文中,我们考虑的是一个虽然相关但却不同的问题,即是否应要求公共资助的医疗机构提供有道德争议的服务,如堕胎、紧急避孕、自愿绝育和自愿安乐死。关于医疗机构责任的实质性争论主要停留在对医疗机构拒绝提供的医疗行为的一阶伦理争论层面;在本文中,我们认为关于医疗机构形而上学的更基本问题为理解医疗机构良心反对的基础提供了一个被忽视的途径。为此,我们阐述了制度良知的形而上学模式,并根据这一模式考虑了三个众所周知的破坏制度性依良心拒服兵役的论点。我们展示了我们对机构的形而上学分析如何为制裁出于良心拒服兵役的机构带来困难。因此,我们认为,有关制度形而上学的问题值得制度良心反对的批评者和捍卫者认真关注。
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引用次数: 0
Psychopathology and Metaphysics: Can One Be a Realist About Mental Disorder? 精神病理学与形而上学:能否成为精神障碍的现实主义者?
IF 1.6 3区 哲学 Q3 ETHICS Pub Date : 2024-04-20 DOI: 10.1093/jmp/jhae013
Simoni Iliadi

Metaphysical realism about mental disorder is the thesis that mental disorder exists mind-independently. There are two ways to challenge metaphysical realism about mental disorder. The first is by denying that mental disorder exists. The second is by denying that mental disorder exists mind-independently. Or, differently put, by arguing that mental disorder is mind-dependent. The aim of this paper is three-fold: (a) to examine three ways in which mental disorder can be said to be mind-dependent (namely, by being causally dependent on the human mind, by being weakly dependent on human attitudes, and by being strongly dependent on human attitudes), (b) to clarify their differences, and (c) to discuss their implications regarding metaphysical realism about mental disorder. I argue that mental disorder being mind-dependent in the first two senses is compatible with metaphysical realism about mental disorder, whereas mental disorder being mind-dependent in the third sense is not.

关于精神障碍的形而上学现实主义是指精神障碍的存在与思维无关。挑战关于精神障碍的形而上学现实主义有两种方法。第一种是否认精神障碍的存在。第二种方法是否认精神障碍独立于思想而存在。或者换一种说法,认为精神障碍是依赖于心智的。本文的目的有三:(a) 探讨精神障碍依赖于心灵的三种方式(即因果依赖于人的心灵、弱依赖于人的态度和强依赖于人的态度),(b) 澄清它们之间的区别,(c) 讨论它们对精神障碍形而上学现实主义的影响。我认为,前两种意义上的精神障碍依赖于心灵与关于精神障碍的形而上学现实主义是一致的,而第三种意义上的精神障碍依赖于心灵则不一致。
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引用次数: 0
The Altruism Requirement as Moral Fiction. 作为道德虚构的利他要求。
IF 1.6 3区 哲学 Q3 ETHICS Pub Date : 2024-04-20 DOI: 10.1093/jmp/jhae011
Luke Semrau

It is widely agreed that living kidney donation is permitted but living kidney sales are not. Call this the Received View. One way to support the Received View is to appeal to a particular understanding of the conditions under which living kidney transplantation is permissible. It is often claimed that donors must act altruistically, without the expectation of payment and for the sake of another. Call this the Altruism Requirement. On the conventional interpretation, the Altruism Requirement is a moral fact. It states a legitimate constraint on permissible transplantation and is accepted on the basis of cogent argument. The present paper offers an alternative interpretation. I suggest the Altruism Requirement is a moral fiction-a kind of motivated falsehood. It is false that transplantation requires altruism. But the Requirement serves a purpose. Accepting it allows kidney donation but not kidney sale. It, in short, rationalizes the Received View.

人们普遍认为,允许活体捐肾,但不允许活体卖肾。这就是 "公认观点"。支持 "接受的观点 "的一种方法是呼吁人们对允许活体肾移植的条件的特定理解。人们经常声称,捐献者必须利他,不求回报,为他人着想。这就是 "利他主义要求"。按照传统的解释,"利他主义要求 "是一个道德事实。它说明了对允许移植的合法限制,并在有力论证的基础上被接受。本文提出了另一种解释。我认为 "利他主义要求 "是一种道德虚构--一种有动机的谎言。移植需要利他主义是假的。但这一要求是有目的的。接受这一要求允许捐肾,但不允许卖肾。简而言之,它使接受观点合理化。
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引用次数: 0
Expanding the Use of Continuous Sedation Until Death and Physician-Assisted Suicide. 扩大使用持续镇静至死和医生协助自杀。
IF 1.6 3区 哲学 Q3 ETHICS Pub Date : 2024-04-20 DOI: 10.1093/jmp/jhae009
Samuel H LiPuma, Joseph P Demarco

The controversy over the equivalence of continuous sedation until death (CSD) and physician-assisted suicide/euthanasia (PAS/E) provides an opportunity to focus on a significant extended use of CSD. This extension, suggested by the equivalence of PAS/E and CSD, is designed to promote additional patient autonomy at the end-of-life. Samuel LiPuma, in his article, "Continuous Sedation Until Death as Physician-Assisted Suicide/Euthanasia: A Conceptual Analysis" claims equivalence between CSD and death; his paper is seminal in the equivalency debate. Critics contend that sedation follows proportionality protocols for which LiPuma's thesis does not adequately account. Furthermore, sedation may not eliminate consciousness, and as such LiPuma's contention that CSD is equivalent to neocortical death is suspect. We not only defend the equivalence thesis, but also expand it to include additional moral considerations. First, we explain the equivalence thesis. This is followed by a defense of the thesis against five criticisms. The third section critiques the current use of CSD. Finally, we offer two proposals that, if adopted, would broaden the use of PAS/E and CSD and thereby expand options at the end-of-life.

关于持续镇静至死(CSD)和医生协助自杀/安乐死(PAS/E)等同性的争议为关注持续镇静至死的重要扩展应用提供了一个机会。持续镇静至死(CSD)和医生协助自杀/安乐死(PAS/E)的等同性所暗示的这种扩展旨在促进生命末期患者的更多自主权。塞缪尔-利普马(Samuel LiPuma)在其文章《持续镇静至死作为医生协助自杀/安乐死:概念分析》中声称持续镇静至死与死亡等同;他的论文在等同性辩论中具有开创性意义。批评者认为,镇静剂遵循相称性协议,而 LiPuma 的论文并没有充分说明这一点。此外,镇静剂可能不会消除意识,因此 LiPuma 关于 CSD 等同于新皮质死亡的论点值得怀疑。我们不仅要为等效论进行辩护,还要将其扩展到更多的道德考量。首先,我们解释等同论。随后,我们针对五种批评意见为该论点进行辩护。第三部分对目前使用的 CSD 进行了批评。最后,我们提出了两项建议,如果这些建议被采纳,将会扩大 PAS/E 和 CSD 的使用范围,从而增加生命末期的选择。
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引用次数: 0
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Journal of Medicine and Philosophy
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