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Is There a "Best" Way for Patients to Participate in Pharmacovigilance? 患者参与药物警戒有 "最佳 "方法吗?
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2025-02-04 DOI: 10.1093/jmp/jhae038
Austin Due

The underreporting of suspected adverse drug reactions hinders pharmacovigilance. Solutions to underreporting are oftentimes directed at clinicians and healthcare professionals. However, given the recent rise of public inclusion in medical science, solutions may soon begin more actively involving patients. I aim to offer an evaluative framework for future possible proposals that would engage patients with the aim of mitigating underreporting. The framework may also have value in evaluating current reporting practices. The offered framework is composed of three criteria that are bioethical, social-epistemic, and pragmatic: (i) patients should not be exposed to undue harms, for example, nocebo effects; (ii) data should be collected, analyzed, and communicated while prioritizing pharmacovigilance's aims, that is, free from industry bias; and (iii) proposals should account for existing and foreseeable pragmatic constraints like clinician "buy in" and existing reporting infrastructure. Proposals to engage patients in pharmacovigilance that fulfil or address these criteria are preferable to those that do not.

药物不良反应的漏报阻碍了药物警戒工作。解决报告不足的办法通常都是针对临床医生和医疗保健专业人员。然而,鉴于最近公众对医学科学的参与度不断提高,解决方案可能很快就会开始更积极地让患者参与进来。我的目的是为未来可能提出的建议提供一个评估框架,让患者参与进来,从而减少漏报现象。该框架对评估当前的报告实践也有价值。所提供的框架由生物伦理、社会学和实用主义三个标准组成:(i) 不应让患者遭受不必要的伤害,例如,避免效应;(ii) 数据的收集、分析和交流应优先考虑药物警戒的目标,即不受行业偏见的影响;(iii) 建议应考虑到现有的和可预见的实用主义限制,如临床医生的 "认同 "和现有的报告基础设施。关于让患者参与药物警戒的建议,如果符合或满足这些标准,则优于不符合或不满足这些标准的建议。
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引用次数: 0
The WEIRD Trio: The Cultural Gap between Physicians, Learners, and Patients in Pluralistic Societies. WEIRD三人组:多元社会中医生、学习者和患者之间的文化差距。
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2025-02-04 DOI: 10.1093/jmp/jhae040
Lester Liao

Physicians are shaped by sociological and philosophical factors that often differ from those of their patients. This is of particular concern in pluralistic societies when navigating ethical disagreements because physicians often misunderstand or even dismiss patient perspectives as being irrational. This paper examines these factors and why many physicians approach ethics as they do while elucidating various patient perspectives and demonstrating how they make sense when considered from a different cultural worldview. Many physicians are trained in contexts that are WEIRD: Western, educated, industrialized, rich, and democratic. These sociological characteristics tend to go hand in hand with the trio of individualism, secularism, and existentialism. These then shape an approach to ethics that focuses on the individual patient, makes no reference to the divine, and focuses on a patient's personal desires. This contrasts significantly with many patients who are collectivistic or religious, and then make rational decisions based on other values. The social fact of pluralism implores physicians to temper confidence in their own cultures while considering others to promote mutual understanding and improved care. This paper concludes with a discussion of how bridges can be built across cultures without sliding into relativism, beginning with recognizing and communicating our shared moral intuitions.

医生受社会学和哲学因素的影响,往往与病人的观点不同。在多元化社会中,当出现伦理分歧时,这一点尤其值得关注,因为医生往往会误解甚至摒弃病人的观点,认为其不合理。本文探讨了这些因素,以及为什么许多医生在处理伦理问题时会这样做,同时阐明了病人的各种观点,并展示了这些观点在不同文化世界观下的意义。许多医生都是在 "奇怪 "的环境中接受培训的:西方、受过教育、工业化、富裕和民主。这些社会学特征往往与个人主义、世俗主义和存在主义三者齐头并进。这些特点形成了一种以病人个体为中心、不提及神灵、注重病人个人愿望的伦理学方法。这与许多患者的集体主义或宗教信仰形成鲜明对比,他们会根据其他价值观做出理性决定。多元化的社会事实要求医生在考虑其他文化的同时,也要克制对自身文化的信心,以促进相互理解和改善护理。本文最后讨论了如何在不陷入相对主义的情况下建立起跨文化的桥梁,首先是认识和交流我们共同的道德直觉。
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引用次数: 0
The Journal After Fifty Years. 五十年后的期刊
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2025-02-04 DOI: 10.1093/jmp/jhae041
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引用次数: 0
Communicating Genetic Information: An Empathy-based Framework. 遗传信息交流:基于移情的框架。
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2025-02-04 DOI: 10.1093/jmp/jhae036
Riana J Betzler, Jonathan Roberts

Contemporary healthcare environments are becoming increasingly informationally demanding. This requires patients, and those supporting them, to engage with a broad range of expert knowledge. At the same time, patients must find ways to make sense of this information in the context of their own values and needs. In this article, we confront the problem of communication in our current age of complexity. We do this by focusing on a field that has already had to grapple with these issues directly: genetic counseling. We articulate an empathy-based framework that provides a way to integrate the teaching and counseling models of genetic counseling. As well as being useful for those providing genetic counseling in the era of genomic medicine, this framework has the potential to address challenges of communication in healthcare settings beyond genetic counseling. Furthermore, it has important ramifications for ethical debates about autonomy and decision-making.

当代医疗环境对信息的要求越来越高。这就要求患者和那些支持他们的人接触广泛的专家知识。与此同时,患者必须找到在自己的价值观和需求背景下理解这些信息的方法。在本文中,我们将面对当今这个复杂时代的沟通问题。我们通过关注一个已经不得不直接解决这些问题的领域来做到这一点:遗传咨询。我们阐明了一个基于移情的框架,提供了一种整合遗传咨询的教学和咨询模型的方法。除了对基因组医学时代提供遗传咨询的人有用外,该框架还具有解决遗传咨询之外的医疗保健环境中沟通挑战的潜力。此外,它还对有关自主和决策的伦理辩论产生了重要影响。
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引用次数: 0
Where There's Hope, There's Life 1 : On the Importance of Hope in Health Care. 哪里有希望,哪里就有生命 1:论希望在医疗保健中的重要性。
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2025-02-04 DOI: 10.1093/jmp/jhae037
Steve Clarke, Justin Oakley

It is widely supposed that it is important to ensure that patients undergoing medical procedures hope that their treatments will be successful. But why is hope so important, if indeed it is? After examining the answers currently on offer in the literature, we identify a hitherto unrecognized reason for supposing that it is important that patients possess hope for a successful treatment, which draws on prospect theory, Kahneman and Tversky's hugely influential descriptive theory about decision-making in situations of risk and uncertainty. We also consider some concerns about patient consent and the potential manipulation of patients that are raised by our account.

人们普遍认为,必须确保接受医疗程序的病人对治疗的成功抱有希望。但为什么希望如此重要呢?在研究了目前文献中提供的答案后,我们从前景理论(卡尼曼和特维尔斯基关于风险和不确定性情况下决策的极具影响力的描述性理论)中找到了一个迄今为止尚未被认识到的理由,即认为病人对成功治疗抱有希望非常重要。我们还考虑了我们的论述所引发的有关病人同意和可能操纵病人的一些担忧。
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引用次数: 0
The Role of Hospice and Palliative Medicine in the Ars Moriendi. 安宁疗护与姑息治疗在《莫尔迪之歌》中的作用。
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2025-02-04 DOI: 10.1093/jmp/jhae039
Levi Durham

There is disagreement among physicians and medical ethicists on the precise goals of Hospice and Palliative Medicine (HPM). Some think that HPM's goals should differ from those of other branches of medicine and aim primarily at lessening pain, discomfort, and confusion, while others think that HPM's practices should aim, like all other branches of medicine, at promoting health. I take the latter position: using the ars moriendi to set a standard for what it means to die well, I argue that if HPM's practices were to aim at mitigating suffering with little regard to promoting health, some patients would die worse deaths than if HPM's practices were to aim at health. According to the ars moriendi, flourishing at the end of one's life requires that persons exercise their agency and pursue the goods most important to them. On this view, HPM's practices should promote patients' health to enable them to pursue these goods.

医生和医学伦理学家对安宁与姑息医学(HPM)的确切目标存在分歧。一些人认为,安宁与姑息医学的目标应不同于其他医学分支,主要是为了减轻痛苦、不适和困惑,而另一些人则认为,安宁与姑息医学的实践应与所有其他医学分支一样,以促进健康为目标。我持后一种立场:我以 "死亡之神"(ars moriendi)为标准,认为如果人道精神医学的实践以减轻痛苦为目标,而很少考虑促进健康,那么一些病人的死状会比以健康为目标的人道精神医学更糟糕。根据ars moriendi,一个人在生命最后阶段的繁荣需要他行使自己的能动性,追求对他来说最重要的东西。根据这一观点,HPM 的做法应促进病人的健康,使他们能够追求这些利益。
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引用次数: 0
Changing the Paradigm: Practical Wisdom as True North in Medical Education.
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2025-02-01 DOI: 10.1093/jmp/jhae048
Margaret L Plews-Ogan

The practice of medicine is a complex endeavor requiring high levels of knowledge and technical capability, and the capacity to apply the skills and knowledge to do the right thing in the right way, for the right reason, in a particular context. The orchestration of the virtues, managing uncertainty, applying knowledge and technical skills to a particular individual in a particular circumstance, and exercising the virtues in challenging circumstances, are the tasks of practical wisdom. Centuries ago, Aristotle suggested that capacities for wise action are developed through practice, experience, and reflection. Neuroscience and cognitive psychology are now beginning to contribute to our understanding of the complex interplay between emotion, cognition, and behavior that is necessary for wise action, and how this capacity for wise action can be developed. In this paper, I propose that wisdom offers an appropriate true north for medical education. Wisdom shifts the focus beyond the simple acquisition of knowledge and technical skills and integrates essential virtues like compassion, trustworthiness, humility, and the balancing of the virtues, into the professional formation for medical students. Informed by the humanities, the neurosciences, and the social sciences, we must now integrate the skills and practices necessary to the development of practical wisdom into medical education at all levels.

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引用次数: 0
Virtue Monism and Medical Practice: Practical Wisdom as Cross-Situational Ethical Expertise.
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2025-02-01 DOI: 10.1093/jmp/jhae051
Mario De Caro, Federico Bina, Sofia Bonicalzi, Riccardo Brunetti, Michel Croce, Skaistė Kerusauskaite, Claudia Navarini, Elena Ricci, Maria Silvia Vaccarezza

This article defends the centrality of practical wisdom in medical practice by building on a monistic view of moral virtue, termed the "Aretai model," according to which possession of practical wisdom is necessary and sufficient for virtuousness, grounding both moral growth and effective moral behavior. From this perspective, we argue that practical wisdom should be conceived as a cross-situational ethical expertise consisting of four skills:moral perception, moral deliberation, emotion regulation, and moral motivation. Conceiving of practical wisdom as both overall virtuousness and ethical expertise makes it possible to deal adequately with the uniqueness of concrete ethically relevant situations. We contend that this becomes particularly evident in the context of medical practice, both in terms of decision-making and action-taking, especially in the most challenging or contentious clinical cases. We conclude the article by suggesting the potential implications of the Aretai model for continuing education in medical and healthcare professions.

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引用次数: 0
Understanding the Psychology of Practical Wisdom.
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2025-01-22 DOI: 10.1093/jmp/jhae050
Howard Nusbaum

The longstanding view of doctors as scientists has been an emphasis in the MCAT and medical school training. However, the AAMC recommended recognizing the importance of social and behavioral science for medicine. There is also a growing realization that being a smart problem solver and the physician as scientist model emphasizes a cold cognitive problem-solving paradigm that overlooks other human capacities that may be critical to medical reasoning and decision-making. Considering a smart physician versus a wise physician, intelligence and problem-solving are important, but a wise physician can use other important capacities beyond intelligence and rationality. This could benefit patients by introducing patient and family perspective taking, as well as compassion in doctor-patient interaction. By reconceptualizing professions from the perspective of practical wisdom, this may increase resilience to problems such as burnout. I outline some psychological capacities viewed as important in wise reasoning that are not about traditional views of intelligence. I argue that wise reasoning is not a native talent but a skill that can be developed. I argue that different kinds of experiences can increase aspects of empathy, epistemic humility, perspective taking, and wise reasoning and I examine evidence that wise reasoning may increase resilience.

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引用次数: 0
Challenges Facing the Appeal to Practical Wisdom in Medicine and Beyond. 医学及其他领域对实践智慧诉求面临的挑战。
IF 1.3 3区 哲学 Q3 ETHICS Pub Date : 2025-01-07 DOI: 10.1093/jmp/jhae047
Christian B Miller

As work on practical wisdom and medicine accelerates, now is a good time to outline some important challenges that any approach to developing an account of this virtue faces. More specifically, I develop five challenges having to do with the existence and nature of practical wisdom, and whether it connects with objective and general normative truths. The main goal is to provide a guide to the challenges themselves and some of the options available for tackling them, rather than trying to resolve them here.

随着对实用智慧和医学的研究加速,现在是勾勒出任何发展这种美德的方法所面临的一些重要挑战的好时机。更具体地说,我提出了与实践智慧的存在和本质有关的五个挑战,以及它是否与客观和一般规范真理有关。本文的主要目标是为挑战本身提供指导,并提供一些可用的解决方案,而不是试图在这里解决它们。
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引用次数: 0
期刊
Journal of Medicine and Philosophy
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