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“You tell him that ‘baby, I am protecting myself’”: Women’s agency and constraint around willingness to use pre-exposure prophylaxis in the Masibambane Study “你告诉他‘宝贝,我在保护自己’”:Masibambane研究中女性对使用暴露前预防的代理和约束
IF 2.4 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-01-01 DOI: 10.1177/17455057221087117
A. Harrison, Nonhlonipho Bhengu, Lori Miller, T. Exner, Nonkululeko Tesfay, Slindile Magutshwa, Silindile Khumalo, S. Bergam, S. Hoffman, J. Hanass-Hancock
Objectives: To explore women’s willingness to consider using pre-exposure prophylaxis for HIV prevention in the context of gendered relationship dynamics, in Durban, South Africa. Methods: As formative research prior to development of a gender-informed intervention to introduce pre-exposure prophylaxis to young, urban, educated women, we conducted six focus-group discussions and eight in-depth interviews with 46 women ages 18–25 years, who were not current pre-exposure prophylaxis users. Women were recruited from clinic and community settings using a criterion-based snowball sampling technique. Qualitative data were coded and analyzed thematically, with a team-based consensus approach for final coding, analytical decisions, and data interpretation. Results: Women clearly understood the benefits of pre-exposure prophylaxis for themselves and their partners, focusing on promoting health and their right to protect themselves from HIV infection. At the same time, and in accordance with findings from other studies, women were realistic about the concerns that would arise among male partners, including disapproval, loss of trust, possible loss of the relationship, and in some instances, the potential for violence, if they were to propose pre-exposure prophylaxis use. To resolve this tension, some women advocated for covert use as the best option for themselves and others argued for disclosure, proposing various approaches to working with partners to adopt pre-exposure prophylaxis. The suggestion that both partners use pre-exposure prophylaxis was made repeatedly. Thus, women sought to avoid discussions of trust or lack of trust and a partner’s possible infidelities, choosing instead to focus on preserving or even building a relationship through suggesting pre-exposure prophylaxis use. Conclusion: Women offered diverse narratives on agency and constraint in relation to choosing pre-exposure prophylaxis as a future prevention strategy, as well as ways to engage with their male partners about pre-exposure prophylaxis. These findings speak to the need for interventions to bolster women’s confidence, sense of empowerment, and their communication and decision-making skills for successful HIV prevention.
目的:在南非德班,探讨妇女是否愿意考虑在性别关系动态的背景下使用暴露前预防来预防艾滋病毒。方法:作为在制定性别知情干预措施之前的形成性研究,向年轻、城市、受过教育的女性介绍暴露前预防措施,我们对46名18-25岁的女性进行了6次焦点小组讨论和8次深入访谈 年,他们不是目前的暴露前预防用药者。采用基于标准的滚雪球抽样技术从诊所和社区招募妇女。定性数据按主题进行编码和分析,采用基于团队的共识方法进行最终编码、分析决策和数据解释。结果:妇女清楚地了解暴露前预防对自己和伴侣的好处,重点是促进健康和保护自己免受艾滋病毒感染的权利。同时,根据其他研究的结果,女性对男性伴侣之间可能出现的问题持现实态度,包括不赞成、失去信任、可能失去关系,以及在某些情况下,如果她们建议使用暴露前预防措施,可能会发生暴力。为了解决这种紧张关系,一些女性主张将秘密使用作为自己的最佳选择,而另一些女性则主张披露,提出了与伴侣合作采取暴露前预防措施的各种方法。建议伴侣双方使用暴露前预防措施的建议被反复提出。因此,女性试图避免讨论信任或缺乏信任以及伴侣可能不忠的问题,而是选择通过建议使用暴露前预防措施来专注于维护甚至建立关系。结论:女性提供了关于选择暴露前预防作为未来预防策略的代理和约束的不同叙述,以及与男性伴侣接触暴露前预防的方式。这些发现表明,需要采取干预措施,增强妇女的信心、赋权感,以及她们成功预防艾滋病毒的沟通和决策技能。
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引用次数: 3
Using machine learning to predict help-seeking among 2016–2018 Pregnancy Risk Assessment Monitoring System participants with postpartum depression symptoms 使用机器学习预测2016-2018年妊娠风险评估监测系统中有产后抑郁症症状的参与者的求助情况
IF 2.4 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-01-01 DOI: 10.1177/17455057221139664
R. Fischbein, Heather L Cook, K. Baughman, S. Díaz
Background: Despite the importance of early identification and treatment, postpartum depression often remains largely undiagnosed with unreported symptoms. While research has identified several factors as prompting help-seeking for postpartum depression symptoms, no research has examined help-seeking for postpartum depression using data from a multi-state/jurisdictional survey analyzed with machine learning techniques. Objectives: This study examines help-seeking among people with postpartum depression symptoms using and demonstrating the utility of machine learning techniques. Methods: Data from the 2016–2018 Pregnancy Risk Assessment Monitoring System, a cross-sectional survey matched with birth certificate data, were used. Six US states/jurisdictions included the outcome help-seeking for postpartum depression symptoms and were used in the analysis. An ensemble method, “Super Learner,” was used to identify the best combination of algorithms and most important variables that predict help-seeking among 1920 recently pregnant people who screen positive for postpartum depression symptoms. Results: The Super Learner predicted well and had an area under the receiver operating curve of 87.95%. It outperformed the highest weighted algorithms which were conditional random forest and stochastic gradient boosting. The following variables were consistently among the top 10 most important variables across the algorithms for predicting increased help-seeking: participants who reported having been diagnosed with postpartum depression, having depression during pregnancy, living in particular US states, being a White compared to Black or Asian American individual, and having a higher maternal body mass index at the time of the survey. Conclusion: These results show the utility of using ensemble machine learning techniques to examine complex topics like help-seeking. Healthcare providers should consider the factors identified in this study when screening and conducting outreach and follow-up for postpartum depression symptoms.
背景:尽管早期识别和治疗很重要,但产后抑郁症通常在很大程度上仍未得到诊断,症状未报告。虽然研究已经确定了促使产后抑郁症症状寻求帮助的几个因素,但没有研究使用机器学习技术分析的多州/司法管辖区调查数据来检查产后抑郁症的寻求帮助。目的:本研究使用并展示了机器学习技术的实用性,调查了产后抑郁症患者的求助情况。方法:使用2016–2018年妊娠风险评估监测系统的数据,这是一项与出生证明数据相匹配的横断面调查。美国六个州/司法管辖区纳入了产后抑郁症症状的结果求助,并用于分析。一种名为“超级学习者”的综合方法被用来确定1920名产后抑郁症症状筛查呈阳性的新近怀孕者中预测求助的算法和最重要变量的最佳组合。结果:Super Learner预测效果好,在受试者工作曲线下的面积为87.95%,优于条件随机森林和随机梯度提升等加权最高的算法。以下变量始终是预测求助增加的算法中最重要的十个变量之一:报告被诊断患有产后抑郁症、怀孕期间患有抑郁症、生活在美国特定州、与黑人或亚裔相比是白人的参与者,并且在调查时具有较高的母体体重指数。结论:这些结果表明了使用集成机器学习技术来检查诸如求助之类的复杂主题的实用性。医疗保健提供者在对产后抑郁症症状进行筛查、外展和随访时,应考虑本研究中确定的因素。
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引用次数: 0
Willingness to use and distribute HIV self-test kits to clients and partners: A qualitative analysis of female sex workers’ collective opinion and attitude in Côte d’Ivoire, Mali, and Senegal 向客户和伴侣使用和分发艾滋病毒自检试剂盒的意愿:Côte科特迪瓦、马里和塞内加尔女性性工作者集体意见和态度的定性分析
IF 2.4 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-01-01 DOI: 10.1177/17455057221092268
O. Ky-Zerbo, A. Desclaux, S. Boye, Anthony Vautier, Nicolas Rouveau, B. Kouadio, Arlette Simo Fotso, D. Pourette, M. Maheu-Giroux, S. Sow, Cheick Sidi Camara, Clémence Doumenc-Aïdara, A. Keita, M. Boily, R. Silhol, Marc d’Elbée, A. Bekelynck, Papa Alioune Gueye, Papa Moussa Diop, Olivier Geoffroy, Odé Kanku Kamemba, S. Diallo, E. Ehui, Cheick Tidiane Ndour, J. Larmarange
Background: In West Africa, female sex workers are at increased risk of HIV acquisition and transmission. HIV self-testing could be an effective tool to improve access to and frequency of HIV testing to female sex workers, their clients and partners. This article explores their perceptions regarding HIV self-testing use and the redistribution of HIV self-testing kits to their partners and clients. Methods: Embedded within ATLAS, a qualitative study was conducted in Côte-d’Ivoire, Mali, and Senegal in 2020. Nine focus group discussions were conducted. A thematic analysis was performed. Results: A total of 87 participants expressed both positive attitudes toward HIV self-testing and their willingness to use or reuse HIV self-testing. HIV self-testing was perceived to be discreet, confidential, and convenient. HIV self-testing provides autonomy from testing by providers and reduces stigma. Some perceived HIV self-testing as a valuable tool for testing their clients who are willing to offer a premium for condomless sex. While highlighting some potential issues, overall, female sex workers were optimistic about linkage to confirmatory testing following a reactive HIV self-testing. Female sex workers expressed positive attitudes toward secondary distribution to their partners and clients, although it depended on relationship types. They seemed more enthusiastic about secondary distribution to their regular/emotional partners and regular clients with whom they had difficulty using condoms, and whom they knew enough to discuss HIV self-testing. However, they expressed that it could be more difficult with casual clients; the duration of the interaction being too short to discuss HIV self-testing, and they fear violence and/or losing them. Conclusion: Overall, female sex workers have positive attitudes toward HIV self-testing use and are willing to redistribute to their regular partners and clients. However, they are reluctant to promote such use with their casual clients. HIV self-testing can improve access to HIV testing for female sex workers and the members of their sexual and social network.
背景:在西非,女性性工作者感染和传播艾滋病毒的风险增加。艾滋病毒自我检测可能是一种有效的工具,可以改善女性性工作者、她们的客户和伴侣获得艾滋病毒检测的机会和频率。本文探讨了他们对艾滋病毒自检使用和艾滋病毒自检包重新分配给他们的伴侣和客户的看法。方法:嵌入ATLAS,于2020年在Côte-d科特迪瓦、马里和塞内加尔进行定性研究。共进行了九次焦点小组讨论。进行了专题分析。结果:共有87名参与者对HIV自检持积极态度,并愿意使用或重复使用HIV自检。艾滋病毒自检被认为是谨慎、保密和方便的。艾滋病毒自我检测提供了不受提供者检测的自主权,并减少了耻辱感。有些人认为艾滋病毒自我检测是一种有价值的工具,可以检测那些愿意支付额外费用进行无套性行为的客户。虽然强调了一些潜在的问题,但总体而言,女性性工作者对在反应性艾滋病毒自我检测后进行确认性检测的联系持乐观态度。女性性工作者对向伴侣和客户进行二次分配持积极态度,尽管这取决于关系类型。他们似乎更热衷于向他们的固定/情感伴侣和固定客户分发避孕套,他们很难与他们使用避孕套,并且他们足够了解他们来讨论艾滋病毒自我检测。然而,他们表示,与临时客户打交道可能会更加困难;互动时间太短,无法讨论艾滋病毒自我检测,他们害怕暴力和/或失去艾滋病毒自我检测。结论:总体而言,女性性工作者对艾滋病毒自检的态度是积极的,并愿意将其重新分配给其固定伴侣和客户。然而,他们不愿意向他们的临时客户推广这种使用。艾滋病毒自我检测可以改善女性性工作者及其性和社会网络成员获得艾滋病毒检测的机会。
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引用次数: 5
An Exploratory Study of Gender Role Stress and Psychological Distress of Women in Kosovo 科索沃妇女性别角色压力与心理困扰的探索性研究
IF 2.4 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-01-01 DOI: 10.1177/17455057221097823
Kaltrina Kelmendi, L. Jemini-Gashi
Introduction: Although investigations of changing gender roles have been performed globally, most studies have been conducted in high-income countries, and studies from emerging and developing countries are lacking. This study aims to examine the factor structure of the feminine gender role stress scale among women (FGRS) and explore its relationship with psychological distress (PD). Methods: A cross-sectional study was carried out with 656 women from Kosovo using a convenience sampling technique during October 2017 and March 2018. The data were collected through face-to-face interviews and analyzed using the Statistical Package for the Social Sciences version 21 and Mplus 7.3. Confirmatory factor analysis (CFA) and path analysis were used to understand the goodness-of-fit of the FGRS scale in the Kosovo context and explore the relationship between the FGRS scale and PD when treated as latent variables. Multivariance analysis of variance (ANOVA) was used to understand the differences between groups of women based on employment and FGRS. Multinomial logistic regression was used to assess the prediction of different domains of FGRS for PD separately for each category while controlling for age. Results: After demonstrating that the five-factor model of the FGRS showed a good fit to the data in this sample of Kosovo women, analyses revealed that the FGRS domains (fear of victimization and behaving with assertiveness) were positively associated with psychological distress. Conclusion: The findings validate the usefulness of the FGRS scale in a sample of Kosovar women. The intersectionality perspective was used to interpret the importance of multiple layers of vulnerabilities and their coexistence, including education, socioeconomic status, and their implications for health inequalities.
引言:尽管在全球范围内对性别角色的变化进行了调查,但大多数研究都是在高收入国家进行的,缺乏来自新兴国家和发展中国家的研究。本研究旨在检验女性性别角色压力量表(FGRS)的因素结构,并探讨其与心理困扰(PD)的关系。方法:在2017年10月至2018年3月期间,使用方便抽样技术对656名科索沃妇女进行了横断面研究。数据是通过面对面访谈收集的,并使用社会科学版21和Mplus 7.3的统计包进行分析。使用验证性因素分析(CFA)和路径分析来理解FGRS量表在科索沃背景下的拟合优度,并探索将FGRS量计作为潜在变量时与PD之间的关系。采用多因素方差分析(ANOVA)来了解基于就业和FGRS的女性群体之间的差异。在控制年龄的同时,使用多项式逻辑回归分别评估每个类别的FGRS对PD的不同领域的预测。结果:在证明FGRS的五因素模型与科索沃妇女样本中的数据非常吻合后,分析表明,FGRS领域(对受害的恐惧和行为自信)与心理困扰呈正相关。结论:研究结果验证了FGRS量表在科索沃妇女样本中的有用性。交叉性视角被用来解释多层脆弱性及其共存的重要性,包括教育、社会经济地位及其对健康不平等的影响。
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引用次数: 2
Pregnant women’s knowledge, attitude, and associated factors toward obstetric ultrasound in public hospitals, Ethiopia, 2021: Multi-centered cross-sectional study 埃塞俄比亚,2021年公立医院孕妇对产科超声的知识、态度及相关因素:多中心横断面研究
IF 2.4 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-01-01 DOI: 10.1177/17455057221091357
W. Molla, N. Mengistu, Aregahegn Wudneh
Background: Obstetric ultrasound is a harmless, cheap, and noninvasive imaging modality that helps to scan a pregnant mother and delivers parents with a real-time image of the fetus. As the number of pregnancies rises globally, the demand for obstetric ultrasound becomes even more pressing. Objectives: To assess pregnant women’s knowledge, attitude, and associated factors toward obstetric ultrasound in public hospitals, Ethiopia. Methods: Institutional based cross-sectional study was employed. Systematic random technique was used to select 419 pregnant women from 10 April 2021 through 2 June 2021. A structured questionnaire was used to collect data during a face-to-face interview. Then the data were coded, cleaned, and entered into Epidemiological data version (EPIDATA) 3.1 and exported to the statistical package for Social Science version 23.0 for analyses. Bivariate and multivariable logistic regression model was used to identify statistically significant associations between dependent and independent variables. The odds ratio at 95% confidence interval with p-value 0.05% was considered statistically significant. Result: The majority of the study participants, 179 (42.8%), have ages ⩾ 25 years. Magnitude of having good knowledge and positive attitude of pregnant women toward obstetric ultrasound was 35.5% and 69.5%, respectively. Residence (adjusted odds ratio: 3.934; 95% confidence interval: 3.125–6.761), educational status (adjusted odds ratio: 3.614; 95% confidence interval: 1.986–5.964), and parity (adjusted odds ratio: 2.7621; 95% confidence interval: 1.68–3.275) were significantly associated with knowledge. Whereas exposure to obstetrical ultrasound in current pregnancy (adjusted odds ratio: 2.726; 95% confidence interval: 1.632–3.629), knowledge on obstetrical ultrasound (adjusted odds ratio: 3.92; 95% confidence interval: 1.324–3.120), and educational status (adjusted odds ratio: 2.84; 95% confidence interval: 1.337–3.381) were significantly associated with attitude. Conclusion: The level of good knowledge and positive attitude toward obstetric ultrasound was 35.5% and 69.5%, respectively, and it can be improved with appropriate interventions like ensuring the practice of obstetric ultrasound scan to all antenatal women. Obstetric care providers at the antenatal care units should advice pregnant women for obstetric ultrasound scan as per World Health Organization recommendations of one obstetric ultrasound scan before 24 weeks of gestation.
背景:产科超声是一种无害的、廉价的、无创的成像方式,它有助于扫描怀孕的母亲,并为父母提供胎儿的实时图像。随着全球怀孕人数的增加,对产科超声的需求变得更加迫切。目的:了解埃塞俄比亚公立医院孕妇对产科超声的知识、态度及相关因素。方法:采用基于机构的横断面研究。采用系统随机技术从2021年4月10日至2021年6月2日选取了419名孕妇。在面对面访谈中,采用结构化问卷收集数据。然后对数据进行编码、清洗,输入流行病学数据版本(EPIDATA) 3.1,导出到社会科学版本23.0的统计包中进行分析。使用双变量和多变量逻辑回归模型来确定因变量和自变量之间的统计学显著相关性。比值比在95%置信区间p值为0.05%时被认为具有统计学意义。结果:大多数研究参与者,179(42.8%),年龄大于或等于25岁。孕妇对产科超声知识知晓率为35.5%,对产科超声态度积极率为69.5%。居住地(调整后优势比:3.934;95%可信区间:3.125-6.761)、教育状况(校正优势比:3.614;95%置信区间:1.986-5.964)和奇偶性(校正优势比:2.7621;95%置信区间:1.68-3.275)与知识显著相关。而妊娠期接受产科超声检查(调整优势比:2.726;95%可信区间:1.632-3.629)、产科超声知识(调整优势比:3.92;95%可信区间:1.324-3.120)、教育状况(调整后优势比:2.84;95%可信区间:1.337 ~ 3.381)与态度显著相关。结论:产妇对产科超声的知晓率为35.5%,对产科超声的积极态度为69.5%,通过适当的干预措施,如确保所有产前妇女都能进行产科超声检查,可以提高产科超声知晓率和积极态度。产前保健单位的产科护理提供者应建议孕妇进行产科超声扫描,按照世界卫生组织的建议,在妊娠24周之前进行一次产科超声扫描。
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引用次数: 0
Key recommendations for developing a national action plan to advance the sexual and reproductive health and rights of women living with HIV in Canada 关于制定国家行动计划以促进加拿大感染艾滋病毒妇女的性健康和生殖健康及权利的主要建议
IF 2.4 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-01-01 DOI: 10.1177/17455057221090829
A. Kaida, B. Cameron, Tracey Conway, Jasmine Cotnam, Jessica Danforth, A. de Pokomandy, Brenda Gagnier, S. Godoy, Rebecca Gormley, S. Greene, Muluba Habanyama, Mina Kazemi, C. Logie, M. Loutfy, J. MacGillivray, R. Masching, D. Money, V. Nicholson, Zoë Osborne, N. Pick, Margarite Sánchez, W. Tharao, S. Watt, Manjulaa Narasimhan
Action on the World Health Organization Consolidated guideline on sexual and reproductive health and rights of women living with HIV requires evidence-based, equity-oriented, and regionally specific strategies centred on priorities of women living with HIV. Through community–academic partnership, we identified recommendations for developing a national action plan focused on enabling environments that shape sexual and reproductive health and rights by, with, and for women living with HIV in Canada. Between 2017 and 2019, leading Canadian women’s HIV community, research, and clinical organizations partnered with the World Health Organization to convene a webinar series to describe the World Health Organization Consolidated guideline, define sexual and reproductive health and rights priorities in Canada, disseminate Canadian research and best practices in sexual and reproductive health and rights, and demonstrate the importance of community–academic partnerships and meaningful engagement of women living with HIV. Four webinar topics were pursued: (1) Trauma and Violence-Aware Care/Practice; (2) Supporting Safer HIV Disclosure; (3) Reproductive Health, Rights, and Justice; and (4) Resilience, Self-efficacy, and Peer Support. Subsequent in-person (2018) and online (2018–2021) consultation with > 130 key stakeholders further clarified priorities. Consultations yielded five cross-cutting key recommendations: 1. Meaningfully engage women living with HIV across research, policy, and practice aimed at advancing sexual and reproductive health and rights by, with, and for all women. 2. Centre Indigenous women’s priorities, voices, and perspectives. 3. Use language that is actively de-stigmatizing, inclusive, and reflective of women’s strengths and experiences. 4. Strengthen Knowledge Translation efforts to support access to and uptake of contemporary sexual and reproductive health and rights information for all stakeholders. 5. Catalyse reciprocal relationships between evidence and action such that action is guided by research evidence, and research is guided by what is needed for effective action. Topic-specific sexual and reproductive health and rights recommendations were also identified. Guided by community engagement, recommendations for a national action plan on sexual and reproductive health and rights encourage Canada to enact global leadership by creating enabling environments for the health and healthcare of women living with HIV. Implementation is being pursued through consultations with provincial and national government representatives and policy-makers.
根据世界卫生组织关于艾滋病毒感染妇女性健康和生殖健康及权利的综合准则采取行动,需要以艾滋病毒感染妇女的优先事项为中心,采取循证、公平和针对区域的战略。通过社区-学术伙伴关系,我们确定了制定一项国家行动计划的建议,该计划的重点是为加拿大感染艾滋病毒的妇女、与她们一起以及为她们塑造性健康和生殖健康及权利的有利环境。2017年至2019年间,加拿大领先的妇女艾滋病毒社区、研究和临床组织与世界卫生组织合作,召开了一系列网络研讨会,以描述世界卫生组织的综合指南,确定加拿大的性健康和生殖健康及权利优先事项,传播加拿大在性健康和生殖健康及权利方面的研究和最佳做法,并表明社区-学术伙伴关系和艾滋病毒感染妇女有意义参与的重要性。举办了四个网络研讨会主题:(1)创伤和暴力意识护理/实践;(2) 支持更安全的艾滋病毒披露;(3) 生殖健康、权利和正义;以及(4)弹性、自我效能和同伴支持。随后亲自(2018年)和在线(2018-2021年)咨询 > 130个主要利益攸关方进一步明确了优先事项。协商产生了五项贯穿各领域的关键建议:1。有意义地让感染艾滋病毒的妇女参与旨在促进所有妇女的性健康和生殖健康及权利的研究、政策和实践。2.以土著妇女的优先事项、声音和观点为中心。3.使用积极去污名化、包容和反映女性优势和经历的语言。4.加强知识翻译工作,支持所有利益攸关方获取和吸收当代性健康和生殖健康及权利信息。5.促进证据和行动之间的相互关系,使行动以研究证据为指导,研究以有效行动所需的内容为指导。还确定了针对具体专题的性健康和生殖健康及权利建议。在社区参与的指导下,关于性健康和生殖健康及权利的国家行动计划的建议鼓励加拿大发挥全球领导作用,为感染艾滋病毒的妇女的健康和保健创造有利的环境。目前正在通过与省和国家政府代表和决策者协商来执行。
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引用次数: 0
Prevalence of episiotomy practice and factors associated with it in Ethiopia, systematic review and meta-analysis 埃塞俄比亚外阴切开术的患病率及其相关因素,系统回顾和荟萃分析
IF 2.4 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-01-01 DOI: 10.1177/17455057221091659
Zerihun Figa Deyaso, Tesfaye Temesgen Chekole, Rediet Gido Bedada, W. Molla, Etaferahu Bekele Uddo, Tizalegn Tesfaye Mamo
An episiotomy is one of the most commonly performed obstetrics surgeries indicated in emergencies during the second stage of labor like fetal distress, dystocia, and tight perineum. As a result, this systematic review and meta-analysis aimed to assess the prevalence of episiotomy practice and associated factors in Ethiopia. Ten cross-sectional studies with a total population of 3718 were included in this study. The search was done using online databases like PubMed, HINARI, Web of Science, other gray, and online repositories of Universities. All the included papers were extracted and appraised using the standard extraction sheet format of JOANNA Briggs Institute. The Cochran Q-test and I2 statistics test were used to test the heterogeneity of studies. To detect the publication bias of the included studies, a funnel plot and Egger’s test were used. The pooled prevalence of episiotomy practice and the odds ratio with a 95% confidence interval were presented using forest plots. The overall pooled prevalence of episiotomy practice was 45.11% (95% CI; 37.04–53.18; I2 = 96.3%). Prolonged second stage of labor (OR: 4.79, 95% CI: 3.03, 7.57), face presentation (OR: 4.26, 95% CI: 1.21, 15.07), birth weight > 4000 g (OR: 6.71, 95% CI: 3.14–14.33), instrumental delivery (OR: 4.26, 95% CI 2.95, 6.14), and primiparity (OR: 3.70, 95% CI: 1.90, 7.2) were factors associated with episiotomy practice. The overall prevalence of episiotomy practice was higher in Ethiopia compared to studies conducted in other countries. The prolonged second stage of labor, face presentation, birth weight > 4000 g, instrumental delivery, and primiparity of women were the factors associated with episiotomy practice. Therefore, efforts should be made to prevent routine episiotomy practice through creating awareness, adjusting national guidelines, affecting the World Health Organization episiotomy policy, and monitoring the activities of the health care facilities in executing the protocols.
会阴切开术是最常见的产科手术之一,用于分娩第二阶段的紧急情况,如胎儿窘迫、难产和会阴紧张。因此,本系统综述和荟萃分析旨在评估外阴切开术在埃塞俄比亚的流行程度及其相关因素。本研究纳入了10项横断面研究,共3718人。搜索是使用在线数据库,如PubMed, HINARI, Web of Science,其他灰色和在线大学知识库完成的。所有纳入的论文均采用乔安娜布里格斯研究所的标准提取表格格式进行提取和评价。采用Cochran q检验和I2统计量检验检验研究的异质性。为检测纳入研究的发表偏倚,采用漏斗图和Egger检验。外阴切开术的总流行率和95%置信区间的比值比采用森林图表示。外阴切开术的总流行率为45.11% (95% CI;37.04 - -53.18;i2 = 96.3%)。第二产程延长(OR: 4.79, 95% CI: 3.03, 7.57)、面部表现(OR: 4.26, 95% CI: 1.21, 15.07)、出生体重> 4000 g (OR: 6.71, 95% CI: 3.14-14.33)、器械分娩(OR: 4.26, 95% CI: 2.95, 6.14)和初产(OR: 3.70, 95% CI: 1.90, 7.2)是与会阴切开术相关的因素。与其他国家进行的研究相比,埃塞俄比亚外阴切开术的总体流行率更高。第二产程延长、面部表现、出生体重> 4000 g、辅助分娩和女性初产是影响会阴切开术的因素。因此,应通过提高认识、调整国家准则、影响世界卫生组织的外阴切开术政策和监测卫生保健机构在执行议定书方面的活动,努力防止常规的外阴切开术做法。
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引用次数: 5
The effectiveness of antioxidant therapy (vitamin C) in an experimentally induced mouse model of ovarian endometriosis 抗氧化疗法(维生素C)在实验诱导的卵巢子宫内膜异位症小鼠模型中的有效性
IF 2.4 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-01-01 DOI: 10.1177/17455057221096218
Hayedeh Hoorsan, M. Simbar, F. Tehrani, F. Fathi, N. Mosaffa, H. Riazi, L. Akradi, Sherko Nasseri, Shayan Bazrafkan
Objectives: This study investigates the therapeutic effect of vitamin C on the development of endometrial lesions and fecundity disorders in the ovarian induction model of mouse endometriosis. Methods: Ovarian endometriosis was surgically induced in 14 NMRI female mice (treatment group, N = 7) and (control group, N = 7). Three days after the second surgery (to assess endometriotic implant), the mice were randomized into two intervention groups: control (placebo) and treatment (50 mg/kg vitamin C every two days orally for four weeks) groups. In the oestrus phase, the mice were sacrificed. In macroscopic assessment, endometriotic implants were evaluated in size, volume, weight, growth score and adhesion score. The microscopic assessment examined the ovarian tissue (the number of antral follicles, corpus luteum and atretic follicles) and endometriotic lesion (histologic and trichrome fibrosis scores). Results: Post-treatment implant volume, growth score, adhesion extent score and adhesion severity score were significantly lower in the treatment group (vitamin C) in comparison with the control group (placebo) (p < 0.0001). The difference between the median weight of endometriotic implants, epithelialization of implant tissue, trichrome fibrosis scores and follicle number in the two groups (treatment and control) was statistically significant (p < 0.05). Atretic follicles were significantly decreased after vitamin C therapy (p < 0.05). Although the numbers of corpus luteum seemed to be more preserved in specimens from the control group, there was no statistical significance between the two groups’ histological scores. Conclusion: As a result, we may imply that vitamin C has a significant effect on reducing the induction and growth of endometrial implants, improving the fecundity function of ovaries, and consequently prevention of endometriosis-associated cancers. Further research is needed to improve targeted interventions resulting in the prevention and treatment of human endometriosis.
目的:本研究探讨维生素C对小鼠子宫内膜异位症卵巢诱导模型中子宫内膜病变和繁殖力障碍的治疗作用。方法:14只NMRI雌性小鼠(治疗组,N = 7) 和(对照组,N = 7) 。第二次手术(评估子宫内膜异位植入物)三天后,将小鼠随机分为两个干预组:对照组(安慰剂)和治疗组(每两天口服50 mg/kg维生素C,持续四周)。在发情期,处死小鼠。在宏观评估中,对子宫内膜异位植入物的大小、体积、重量、生长评分和粘附评分进行评估。显微镜评估检查了卵巢组织(窦卵泡、黄体和闭锁卵泡的数量)和子宫内膜异位病变(组织学和三色纤维化评分)。结果:与对照组(安慰剂)相比,治疗组(维生素C)治疗后植入物体积、生长评分、粘附程度评分和粘附严重程度评分显著降低(p < 0.0001)。两组(治疗组和对照组)子宫内膜异位植入物的中位重量、植入物组织的上皮化、三色纤维化评分和卵泡数之间的差异具有统计学意义(p < 维生素C治疗后萎缩卵泡明显减少(p < 0.05)。尽管对照组的标本中黄体数量似乎保存得更多,但两组的组织学评分之间没有统计学意义。结论:因此,我们可能暗示维生素C对减少子宫内膜植入物的诱导和生长,改善卵巢的生殖功能,从而预防子宫内膜异位症相关癌症具有显著作用。需要进一步的研究来改进有针对性的干预措施,从而预防和治疗人类子宫内膜异位症。
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引用次数: 5
Liver transplantation does not increase morbidity or mortality in women undergoing surgery for breast cancer 肝移植不会增加癌症手术妇女的发病率或死亡率
IF 2.4 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2021-11-11 DOI: 10.1177/17455057221097554
G. Veillette, M. Castaldi, S. Roberts, A. Parsikia, A. Choubey, K. Okumura, R. Latifi, Jorge Ortiz
Purpose: The incidence of breast cancer following solid organ transplantation is comparable to the age-matched general population. The rate of de novo breast cancer following liver transplantation varies. Furthermore, there is limited information on the management and outcomes of breast cancer in liver transplant recipients. We aim to evaluate the impact of liver transplantation on breast cancer surgery outcomes and compare the outcomes after breast cancer surgery in liver transplant recipient in transplant versus non-transplant centers. Methods: National Inpatient Sample database was accessed to identify liver transplant recipient with breast cancer. Mortality, complications, hospital charges, and total length of stay were evaluated with multivariate logistic regression testing. Weighted multivariate regression models were employed to compare outcomes at transplant and non-transplant centers. Results: Ninety-nine women met inclusion criteria for liver transplantation + breast cancer and were compared against women with breast cancer without liver transplantation (n = 736,527). Liver transplantation + breast cancer had lower performance status as confirmed via higher Elixhauser Comorbidity Index (20.5% vs 10.2%, p < 0001). There were significantly more complications in the liver transplantation cohort when compared to the non-liver transplant recipient (15.0% vs 8.2%, p = 0.012). However, on multivariate analysis, liver transplantation was not an independent risk factor for post-operative complications following breast cancer surgery (odd ratio, 1.223, p = 0.480). Cost associated with breast cancer care was significantly higher in those with liver transplantation (2.621, p < 0.001). Breast conservation surgery in liver transplantation had shorter length of stay as compared to breast cancer alone (odds ratio, 0.568, p = 0.027) in all hospitals. Conclusion: Liver transplantation does not increase short-term mortality when undergoing breast cancer surgery. Although there were significantly more complications in the liver transplantation cohort when compared to the non-liver transplant recipient (15.0% vs 8.2%, p = 0.012), on multivariate analysis, liver transplantation was not an independent risk factor for postoperative complications following breast cancer surgery. Breast cancer management in liver transplant recipient at non-transplant centers incurred higher charges but no difference in complication rate or length of stay when compared to transplant centers.
目的:实体器官移植后癌症的发病率与年龄匹配的普通人群相当。肝移植后新发癌症的发生率各不相同。此外,关于肝移植受者乳腺癌症的治疗和结果的信息有限。我们的目的是评估肝移植对乳腺癌症手术结果的影响,并比较移植中心和非移植中心的肝移植受者在乳腺癌症手术后的结果。方法:访问全国住院病人样本数据库,确定癌症肝移植受者。死亡率、并发症、住院费用和总住院时间采用多变量逻辑回归检验进行评估。采用加权多变量回归模型比较移植中心和非移植中心的结果。结果:99名女性符合肝移植纳入标准 + 并与未进行肝移植的癌症乳腺癌患者进行比较(n = 736527)。肝移植 + 通过较高的Elixhauser合并症指数证实,癌症的表现状态较低(20.5%对10.2%,p < 0001)。与非肝移植受者相比,肝移植队列中的并发症明显更多(15.0%vs 8.2%,p = 然而,在多变量分析中,肝移植并不是乳腺癌症手术后并发症的独立危险因素(奇数比,1.223,p = 与乳腺癌症治疗相关的费用在肝移植患者中显著升高(2.621,p < 与单纯的乳腺癌症相比,肝移植保乳手术的住院时间更短(比值比,0.568,p = 0.027)。结论:肝移植不增加乳腺癌症手术的短期死亡率。尽管与非肝移植受者相比,肝移植队列中的并发症明显更多(15.0%vs 8.2%,p = 0.012),在多变量分析中,肝移植不是乳腺癌症手术后并发症的独立危险因素。与移植中心相比,非移植中心肝移植受者的乳腺癌症治疗费用更高,但并发症发生率或住院时间没有差异。
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引用次数: 0
Prevention of pre-eclampsia with low dose aspirin in primigravida 小剂量阿司匹林预防初发期子痫前期
IF 2.4 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2020-02-13 DOI: 10.15406/mojwh.2020.09.00264
Oreekha Amin, Nasira Tasnim, S. Naeem
Pre-eclampsia is a multi-system disorder of pregnancy associated with hypertension and proteinuria. Its incidence varies between 2-10%, depending on the population studied. Moreover, it is the second leading cause of direct maternal and fetal deaths in Pakistan.1 Although, there is obvious predisposition in certain people to develop pre-eclampsia, the risk is 5-7% among primigravida women.2 Further, while the origin of the pre-eclampsia remains unclear, it is believed that pre-eclampsia is associated with the deep placentation disorders. The physiological change-over of uterine spiral arteries between 8-16weeks of gestation is the classical placental disorder associated with the pre-eclampsia.3 Moreover; elevated platelet triggering is the set component of pathophysiology of pre-eclampsia. This may persuade to platelet utilization and ensuing the microvasculature’s coagulation system set off, which sequentially leads to endothelial injury, vasospasm and end organ damage.
子痫前期是一种与高血压和蛋白尿相关的妊娠多系统疾病。其发病率在2-10%之间,取决于所研究的人群。此外,在巴基斯坦,子痫是导致产妇和胎儿直接死亡的第二大原因。尽管某些人明显易患先兆子痫,但在初产妇中,风险为5-7%此外,虽然先兆子痫的起源尚不清楚,但人们认为先兆子痫与深部胎盘障碍有关。子宫螺旋动脉在妊娠8-16周之间的生理变化是典型的与子痫前期相关的胎盘紊乱此外;血小板升高触发是子痫前期病理生理的固定组成部分。这可能导致血小板的利用和微血管凝血系统的启动,从而导致内皮损伤、血管痉挛和终末器官损伤。
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引用次数: 4
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Womens Health
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