Pub Date : 2025-11-11eCollection Date: 2025-01-01DOI: 10.1136/bmjsem-2025-002766
Solveig Hausken-Sutter, Christian Moen, Emilie Scholten Sjølie, Christian Thue Bjørndal, Grethe Myklebust, Merete Møller, Hege Grindem
Effective youth sport injury interventions exist, but their use in applied settings is limited by low coach adherence and lack of contextual adaptation. To address this, the #Utviklingsklar intervention was developed, a club-based intervention for youth handball and football, based on interdisciplinary programme theory and collaboration with sport organisation partners and user groups (club leaders, coaches, parents, players). The intervention supports coaches and club leaders in developing team-specific plans to improve injury-preventive practices for warm-up, strength training and pain and injury management. This qualitative feasibility study, based on observation and interview data, examines the acceptability, practicality, possibilities and challenges of #Utviklingsklar's e-learning and workshop activities. Three workshops led by physiotherapists were observed, involving 23 participants (17 coaches, three club leaders and three workshop leaders). Subsequently, 15 participants consented to be interviewed, comprising 10 coaches, two club leaders and three workshop leaders. Data were analysed using deductive thematic analysis principles. The e-learning was found to be user-friendly, accessible and relevant, while the workshop was valued for fostering discussions and collaboration around team-specific injury prevention plans and practices. However, some coaches sought more tailored content (ie, topics related to their own specific training sessions and players), and workshop leaders expressed a need for additional preparation and practice time to feel confident in their roles. Improved communication of #Utviklingsklar's flexible approach, along with enhanced preparation and practice for workshop leaders in supporting coaches' and club leaders' development of team-specific plans and practices, is needed to enhance understanding and engagement across clubs.
{"title":"#Utviklingsklar: a club-based intervention to develop plans and practices for injury prevention in youth sport-acceptability, practicality, possibilities and challenges among club leaders, coaches and workshop leaders.","authors":"Solveig Hausken-Sutter, Christian Moen, Emilie Scholten Sjølie, Christian Thue Bjørndal, Grethe Myklebust, Merete Møller, Hege Grindem","doi":"10.1136/bmjsem-2025-002766","DOIUrl":"10.1136/bmjsem-2025-002766","url":null,"abstract":"<p><p>Effective youth sport injury interventions exist, but their use in applied settings is limited by low coach adherence and lack of contextual adaptation. To address this, the #Utviklingsklar intervention was developed, a club-based intervention for youth handball and football, based on interdisciplinary programme theory and collaboration with sport organisation partners and user groups (club leaders, coaches, parents, players). The intervention supports coaches and club leaders in developing team-specific plans to improve injury-preventive practices for warm-up, strength training and pain and injury management. This qualitative feasibility study, based on observation and interview data, examines the acceptability, practicality, possibilities and challenges of #Utviklingsklar's e-learning and workshop activities. Three workshops led by physiotherapists were observed, involving 23 participants (17 coaches, three club leaders and three workshop leaders). Subsequently, 15 participants consented to be interviewed, comprising 10 coaches, two club leaders and three workshop leaders. Data were analysed using deductive thematic analysis principles. The e-learning was found to be user-friendly, accessible and relevant, while the workshop was valued for fostering discussions and collaboration around team-specific injury prevention plans and practices. However, some coaches sought more tailored content (ie, topics related to their own specific training sessions and players), and workshop leaders expressed a need for additional preparation and practice time to feel confident in their roles. Improved communication of #Utviklingsklar's flexible approach, along with enhanced preparation and practice for workshop leaders in supporting coaches' and club leaders' development of team-specific plans and practices, is needed to enhance understanding and engagement across clubs.</p>","PeriodicalId":47417,"journal":{"name":"BMJ Open Sport & Exercise Medicine","volume":"11 4","pages":"e002766"},"PeriodicalIF":3.2,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12606477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145514551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-05eCollection Date: 2025-01-01DOI: 10.1136/bmjsem-2025-002806
Matthew G Neill, Lauren N Miutz, Michaela K Chadder, Jean-Michel Galarneau, Josh J Burkart, Jonathan D Smirl, Carolyn Emery
Objective: Recovery duration following adolescent sport-related concussion (SRC) is variable. Previous research revealed exercise intolerance is associated with delayed recovery (predominantly male Australian cohort). Additional sport contexts and considerations of sex are necessary. This study investigated sex-specific associations between exercise intolerance and time-to-medical clearance to return-to-sport (RTS) following SRC in adolescents (ages 10-19).
Methods: Adolescent athletes participating in the pan-Canadian SHRed Concussions cohort study were included within 14 days following a physician diagnosed SRC. Participants completed the Buffalo Concussion Treadmill Test (BCTT). Pre-BCTT Sport Concussion Assessment Tool 5 (SCAT5) Symptom Severity Score (SSS;/132) and concussion Overall Condition score (OC;/10) were recorded. Termination criteria for BCTT were participants who experienced ≥3/10 increase for OC (exercise intolerant) or reached volitional fatigue (≥180bpm, ≥18/20 rating of perceived exertion, exercise tolerant).
Results: 281 adolescents (126 male and 155 female), of whom 204 (72.6%) (100 male (79.4%), 104 female (67.1%)) were exercise tolerant and 77 (27.4%) (26 male (20.6%), 51 female (32.9%)) were intolerant following SRC. Based on the point estimate, females had a 1.45 times higher risk of exercise intolerance compared with males (risk ratio=1.45, 95% CI 0.96 to 2.20). Exercise intolerance was associated with a 36% longer medical clearance time to RTS following SRC for females (time ratio=1.36, 95% CI 1.12 to 1.64), while for males, no association was observed (time ratio=1.13, 95% CI 0.90 to 1.42) (adjusted for age, BCTT duration, SCAT5 SSS and days from SRC to BCTT).
Conclusion: Exertion testing may identify female adolescents at higher risk of delayed medical clearance recovery to RTS, informing the comprehensive clinical management of SRC.
目的:青少年运动相关脑震荡(SRC)的恢复时间是可变的。先前的研究表明,运动不耐受与延迟恢复有关(主要是澳大利亚男性队列)。额外的运动背景和性别的考虑是必要的。本研究调查了青少年(10-19岁)SRC后运动不耐受与医疗许可时间(RTS)之间的性别特异性关联。方法:参加泛加拿大SHRed脑震荡队列研究的青少年运动员在医生诊断为SRC后14天内纳入。参与者完成了布法罗脑震荡跑步机测试(BCTT)。记录bctt前运动脑震荡评估工具5 (SCAT5)症状严重程度评分(SSS;/132)和脑震荡总体状况评分(OC;/10)。BCTT的终止标准是OC(运动不耐受)增加≥3/10或达到意志疲劳(≥180bpm,感知运动强度评分≥18/20)的参与者。结果:281名青少年(男性126人,女性155人),其中运动耐受204人(72.6%)(男性100人(79.4%),女性104人(67.1%)),运动不耐受77人(27.4%)(男性26人(20.6%),女性51人(32.9%))。根据点估计,女性患运动不耐受的风险是男性的1.45倍(风险比=1.45,95% CI 0.96 - 2.20)。运动不耐受与女性SRC后到RTS的医学清除时间延长36%相关(时间比=1.36,95% CI 1.12至1.64),而对于男性,没有观察到相关(时间比=1.13,95% CI 0.90至1.42)(调整年龄、BCTT持续时间、SCAT5 SSS和从SRC到BCTT的天数)。结论:用力试验可识别女性青少年延迟医学清除恢复到RTS的高风险,为SRC的综合临床管理提供信息。
{"title":"Exercise intolerance and time to medical clearance to return to sport following sport-related concussion in adolescents.","authors":"Matthew G Neill, Lauren N Miutz, Michaela K Chadder, Jean-Michel Galarneau, Josh J Burkart, Jonathan D Smirl, Carolyn Emery","doi":"10.1136/bmjsem-2025-002806","DOIUrl":"10.1136/bmjsem-2025-002806","url":null,"abstract":"<p><strong>Objective: </strong>Recovery duration following adolescent sport-related concussion (SRC) is variable. Previous research revealed exercise intolerance is associated with delayed recovery (predominantly male Australian cohort). Additional sport contexts and considerations of sex are necessary. This study investigated sex-specific associations between exercise intolerance and time-to-medical clearance to return-to-sport (RTS) following SRC in adolescents (ages 10-19).</p><p><strong>Methods: </strong>Adolescent athletes participating in the pan-Canadian SHRed Concussions cohort study were included within 14 days following a physician diagnosed SRC. Participants completed the Buffalo Concussion Treadmill Test (BCTT). Pre-BCTT Sport Concussion Assessment Tool 5 (SCAT5) Symptom Severity Score (SSS;/132) and concussion Overall Condition score (OC;/10) were recorded. Termination criteria for BCTT were participants who experienced ≥3/10 increase for OC (exercise intolerant) or reached volitional fatigue (≥180bpm, ≥18/20 rating of perceived exertion, exercise tolerant).</p><p><strong>Results: </strong>281 adolescents (126 male and 155 female), of whom 204 (72.6%) (100 male (79.4%), 104 female (67.1%)) were exercise tolerant and 77 (27.4%) (26 male (20.6%), 51 female (32.9%)) were intolerant following SRC. Based on the point estimate, females had a 1.45 times higher risk of exercise intolerance compared with males (risk ratio=1.45, 95% CI 0.96 to 2.20). Exercise intolerance was associated with a 36% longer medical clearance time to RTS following SRC for females (time ratio=1.36, 95% CI 1.12 to 1.64), while for males, no association was observed (time ratio=1.13, 95% CI 0.90 to 1.42) (adjusted for age, BCTT duration, SCAT5 SSS and days from SRC to BCTT).</p><p><strong>Conclusion: </strong>Exertion testing may identify female adolescents at higher risk of delayed medical clearance recovery to RTS, informing the comprehensive clinical management of SRC.</p>","PeriodicalId":47417,"journal":{"name":"BMJ Open Sport & Exercise Medicine","volume":"11 4","pages":"e002806"},"PeriodicalIF":3.2,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12593449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145483363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-29eCollection Date: 2025-01-01DOI: 10.1136/bmjsem-2025-002776
Ryan Summersby, Niamh Sheehan, Chris Bleakley, Brian Caulfield, Mark Matthews, Natalie Klempel, Sinead Holden
Despite the developmental benefits of sport in adolescence, injury is common and can have a profound impact beyond just physical symptoms. This qualitative study aims to explore the lived experiences of adolescent athletes with sports- related injury in Ireland. This was a qualitative study using one-on-one semi-structured interviews and a phenomenology method. Twenty-one secondary school students from across the Island of Ireland aged 15-18 years who had experienced a sports-related injury within the last 2 years agreed to take part. Reflexive thematic analysis was used to analyse the collected data. Seventeen adolescents (eight female, mean age 16.2 (range 15-18) years) from five different sports were included for analysis. Predominantly negative experiences were described with four overarching themes identified through thematic analysis: playing through pain and injury, the social influence on playing through pain and injury behaviour, the psychological impact of sports injury and player confidence and its role in returning to sport. In conclusion, a culture of playing through pain and even injury is widely accepted in adolescent sports and is influenced by the social circles that surround these young athletes. The impact of sports injury goes beyond just the physical, with these athletes experiencing devastation and a loss of identity due to their absence from sport. Sports coaches can help reduce this negative impact by keeping injured players involved in the team/sport as much as possible. Conversely, sports injury also provided opportunity for personal growth in some cases, improving mental resilience and self-reliance.
{"title":"\"I was devastated… sport is like an addiction nearly\": a qualitative study examining young athletes' experiences with injury in sport.","authors":"Ryan Summersby, Niamh Sheehan, Chris Bleakley, Brian Caulfield, Mark Matthews, Natalie Klempel, Sinead Holden","doi":"10.1136/bmjsem-2025-002776","DOIUrl":"10.1136/bmjsem-2025-002776","url":null,"abstract":"<p><p>Despite the developmental benefits of sport in adolescence, injury is common and can have a profound impact beyond just physical symptoms. This qualitative study aims to explore the lived experiences of adolescent athletes with sports- related injury in Ireland. This was a qualitative study using one-on-one semi-structured interviews and a phenomenology method. Twenty-one secondary school students from across the Island of Ireland aged 15-18 years who had experienced a sports-related injury within the last 2 years agreed to take part. Reflexive thematic analysis was used to analyse the collected data. Seventeen adolescents (eight female, mean age 16.2 (range 15-18) years) from five different sports were included for analysis. Predominantly negative experiences were described with four overarching themes identified through thematic analysis: playing through pain and injury, the social influence on playing through pain and injury behaviour, the psychological impact of sports injury and player confidence and its role in returning to sport. In conclusion, a culture of playing through pain and even injury is widely accepted in adolescent sports and is influenced by the social circles that surround these young athletes. The impact of sports injury goes beyond just the physical, with these athletes experiencing devastation and a loss of identity due to their absence from sport. Sports coaches can help reduce this negative impact by keeping injured players involved in the team/sport as much as possible. Conversely, sports injury also provided opportunity for personal growth in some cases, improving mental resilience and self-reliance.</p>","PeriodicalId":47417,"journal":{"name":"BMJ Open Sport & Exercise Medicine","volume":"11 4","pages":"e002776"},"PeriodicalIF":3.2,"publicationDate":"2025-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12574393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-27eCollection Date: 2025-01-01DOI: 10.1136/bmjsem-2025-002686
Libby Jean Gracias, Brooke E Patterson, Andrea B Mosler, Bryn Savill, Indianna Franke, Kay M Crossley, Patrick Clifton, Michael Makdissi, Catherine Willmott, Anik Shawdon, Jonathan Reyes, Matthew G King
Objective: Junior Australian football players with sport-related concussion (SRC) often do not access optimal healthcare. We aimed to evaluate the feasibility of an industry-supported healthcare programme that removed financial and logistical barriers to accessing care for SRC and adherence to the Australian Football League's (AFL) SRC management guidelines.
Methods: Junior Australian football players (from a Melbourne-based league of 9852; under 8-18 competitions) who sustained a suspected or diagnosed SRC during the 2023 season were recruited. Players underwent assessment and management for SRC by a sport and exercise medicine registrar, including return to school and play planning in accordance with the AFL guidelines. Outcomes included programme demand, implementation, acceptability and adherence to the AFL's guidelines (median, (range) days for return to school, training and play).
Results: From 154 eligible players, 58 (37.7%) participated, resulting in a weekly demand of 4.1 players (95% CI 3.1 to 5.2). 49 players were diagnosed with an SRC, and 9 players were cleared for SRC at their initial appointment. 44 players with SRC (89.8%) adhered to all medical advice and returned to play after receiving a medical clearance. All players returned to school (1 (0-10) days), unrestricted training (16 (2-53) days) and play (21 (7-63) days).
Conclusion: The low programme demand indicates financial constraints and/or access to medical practitioners are not the main barriers for players with suspected SRC to formally seek healthcare in a metropolitan context. Those who did participate demonstrated high levels of appointment attendance, acceptability and adherence to AFL guidelines.
目的:澳大利亚青少年足球运动员与运动相关的脑震荡(SRC)往往不能获得最佳的医疗保健。我们的目的是评估行业支持的医疗保健计划的可行性,该计划消除了SRC获得护理的财务和后勤障碍,并遵守了澳大利亚足球联盟(AFL) SRC管理指南。方法:招募在2023赛季期间患有疑似或诊断为SRC的澳大利亚青少年足球运动员(来自墨尔本的9852个联赛;8-18岁以下比赛)。运动员接受了体育和运动医学注册师对SRC的评估和管理,包括根据AFL的指导方针返回学校和比赛计划。结果包括项目需求、实施、可接受性和对AFL指导方针的遵守(中位数,(范围)返回学校、训练和比赛的天数)。结果:在154名符合条件的玩家中,58名(37.7%)参与,导致每周需要4.1名玩家(95% CI 3.1至5.2)。49名球员被诊断为SRC, 9名球员在最初的预约中被批准为SRC。44名患有SRC的球员(89.8%)遵守了所有医疗建议,并在接受医疗检查后重返赛场。所有球员返回学校(1(0-10)天),无限制训练(16(2-53)天)和比赛(21(7-63)天)。结论:低项目需求表明,经济限制和/或获得医疗从业人员并不是怀疑患有SRC的球员在大都市环境中正式寻求医疗保健的主要障碍。那些参与的人表现出高水平的预约出勤率,可接受性和对AFL指导方针的遵守。
{"title":"Industry-supported healthcare programme for concussion management in junior community Australian football.","authors":"Libby Jean Gracias, Brooke E Patterson, Andrea B Mosler, Bryn Savill, Indianna Franke, Kay M Crossley, Patrick Clifton, Michael Makdissi, Catherine Willmott, Anik Shawdon, Jonathan Reyes, Matthew G King","doi":"10.1136/bmjsem-2025-002686","DOIUrl":"10.1136/bmjsem-2025-002686","url":null,"abstract":"<p><strong>Objective: </strong>Junior Australian football players with sport-related concussion (SRC) often do not access optimal healthcare. We aimed to evaluate the feasibility of an industry-supported healthcare programme that removed financial and logistical barriers to accessing care for SRC and adherence to the Australian Football League's (AFL) SRC management guidelines.</p><p><strong>Methods: </strong>Junior Australian football players (from a Melbourne-based league of 9852; under 8-18 competitions) who sustained a suspected or diagnosed SRC during the 2023 season were recruited. Players underwent assessment and management for SRC by a sport and exercise medicine registrar, including return to school and play planning in accordance with the AFL guidelines. Outcomes included programme demand, implementation, acceptability and adherence to the AFL's guidelines (median, (range) days for return to school, training and play).</p><p><strong>Results: </strong>From 154 eligible players, 58 (37.7%) participated, resulting in a weekly demand of 4.1 players (95% CI 3.1 to 5.2). 49 players were diagnosed with an SRC, and 9 players were cleared for SRC at their initial appointment. 44 players with SRC (89.8%) adhered to all medical advice and returned to play after receiving a medical clearance. All players returned to school (1 (0-10) days), unrestricted training (16 (2-53) days) and play (21 (7-63) days).</p><p><strong>Conclusion: </strong>The low programme demand indicates financial constraints and/or access to medical practitioners are not the main barriers for players with suspected SRC to formally seek healthcare in a metropolitan context. Those who did participate demonstrated high levels of appointment attendance, acceptability and adherence to AFL guidelines.</p>","PeriodicalId":47417,"journal":{"name":"BMJ Open Sport & Exercise Medicine","volume":"11 4","pages":"e002686"},"PeriodicalIF":3.2,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12557732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145393851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-27eCollection Date: 2025-01-01DOI: 10.1136/bmjsem-2024-002394
Atle Kongsvold, Mats Flaaten, Eivind Schjelderup Skarpsno, Aleksej Logacjov, Kerstin Bach, Tom Ivar Lund Nilsen, Paul Jarle Mork
Objectives: To examine the contribution of walking, running and cycling to moderate-to-vigorous physical activity (MVPA) and total physical activity (TPA) across and within seasons in adolescents and adults.
Methods: We included 4433 adolescents (mean age 15.4 years, range 13-17, 56.4% female) and 28 082 adults (mean age 53.1 years, range 18-103, 56.9% female) who participated in the population-based HUNT Study from 2017 to 2019. Participants wore two accelerometers (mean wear time 5.6 days (SD 1.1), range 1-7 days), one on the thigh and one on the lower back, to determine MVPA (defined as moderate/brisk walking (>4.0 km/hour), running and cycling) and TPA (MVPA plus slow walking (≤4.0 km/hour)).
Results: Median MVPA (min/week) across seasons was 224 (36% of TPA) in adolescents and 152 (24% of TPA), 150 (22% of TPA), 100 (17% of TPA) and 34 (8% of TPA) in adults aged 18-49, 50-64, 65-74 and ≥75 years, respectively. Slow walking constituted 64% of TPA across seasons among adolescents, increasing to 92% among those aged ≥75 years.Within seasons, moderate/brisk walking constituted 77-82% of MVPA in adolescents and 72-99% in adults. Adolescents accumulated 104 min/week (IQR 58-175) less MVPA during winter than summer. The corresponding differences in adults aged 18-49 and 50-64 years were 59 (40-90) and 51 (33-77), min/week, respectively. Seasonal differences in MVPA were less pronounced in the age groups 65-74 and ≥75 years.
Conclusion: Moderate/brisk walking is the main contributor to MVPA in adolescents and adults. The level of MVPA, its seasonal variation and its relative proportion of TPA decrease from adolescence throughout adulthood.
{"title":"Contribution of walking, running and cycling to moderate-to-vigorous and total physical activity in adolescents and adults across and within seasons: cross-sectional data from the Norwegian HUNT Study.","authors":"Atle Kongsvold, Mats Flaaten, Eivind Schjelderup Skarpsno, Aleksej Logacjov, Kerstin Bach, Tom Ivar Lund Nilsen, Paul Jarle Mork","doi":"10.1136/bmjsem-2024-002394","DOIUrl":"10.1136/bmjsem-2024-002394","url":null,"abstract":"<p><strong>Objectives: </strong>To examine the contribution of walking, running and cycling to moderate-to-vigorous physical activity (MVPA) and total physical activity (TPA) across and within seasons in adolescents and adults.</p><p><strong>Methods: </strong>We included 4433 adolescents (mean age 15.4 years, range 13-17, 56.4% female) and 28 082 adults (mean age 53.1 years, range 18-103, 56.9% female) who participated in the population-based HUNT Study from 2017 to 2019. Participants wore two accelerometers (mean wear time 5.6 days (SD 1.1), range 1-7 days), one on the thigh and one on the lower back, to determine MVPA (defined as moderate/brisk walking (>4.0 km/hour), running and cycling) and TPA (MVPA plus slow walking (≤4.0 km/hour)).</p><p><strong>Results: </strong>Median MVPA (min/week) across seasons was 224 (36% of TPA) in adolescents and 152 (24% of TPA), 150 (22% of TPA), 100 (17% of TPA) and 34 (8% of TPA) in adults aged 18-49, 50-64, 65-74 and ≥75 years, respectively. Slow walking constituted 64% of TPA across seasons among adolescents, increasing to 92% among those aged ≥75 years.Within seasons, moderate/brisk walking constituted 77-82% of MVPA in adolescents and 72-99% in adults. Adolescents accumulated 104 min/week (IQR 58-175) less MVPA during winter than summer. The corresponding differences in adults aged 18-49 and 50-64 years were 59 (40-90) and 51 (33-77), min/week, respectively. Seasonal differences in MVPA were less pronounced in the age groups 65-74 and ≥75 years.</p><p><strong>Conclusion: </strong>Moderate/brisk walking is the main contributor to MVPA in adolescents and adults. The level of MVPA, its seasonal variation and its relative proportion of TPA decrease from adolescence throughout adulthood.</p>","PeriodicalId":47417,"journal":{"name":"BMJ Open Sport & Exercise Medicine","volume":"11 4","pages":"e002394"},"PeriodicalIF":3.2,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12574398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-27eCollection Date: 2025-01-01DOI: 10.1136/bmjsem-2025-002731
Kazutaka Fukushima, Kazuyuki Kamahara, Anna Tomori, Yoshio Nakata
Objectives: To describe the characteristics of COVID-19 among elite Japanese athletes and their return-to-play (RTP) time.
Methods: We retrospectively reviewed clinical records at the Japan Institute of Sports Sciences between June 2022 and May 2023. Elite athletes who underwent periodic health examinations were examined by a physician to confirm COVID-19 history, symptoms and the RTP time.
Results: Of 994 athletes, 456 had a COVID-19 history (mean±SD, 23.3±4.6 years; 56% male). Most infections occurred during the sixth wave (Omicron variant), followed by the seventh and eighth waves, with 88% recorded after the fifth wave. Indoor athletes were more frequently affected than outdoor athletes (306 vs 150, p<0.05). Badminton athletes were the most commonly affected athletes (16%), followed by volleyball (10%) and handball (7%). Among those with a history of COVID-19, 89% reported symptoms, while 11% were asymptomatic. Fever was the most common symptom (80%), followed by sore throat (58%) and cough (44%). The median (IQR) RTP time was 10 (7-14) days. Overall, 472 athletes resumed play within 28 days, while 20 returned after 28 days. RTP delays were more frequent before Omicron (9/59 athletes) than after (11/433 athletes, p<0.05).
Conclusion: COVID-19 was more common among indoor sports athletes, primarily during the Omicron wave, with most cases being symptomatic but resolving quickly. These findings likely reflect factors such as close-contact training, immune changes during intensive training and international travel and may help characterise COVID-19 outcomes in elite athletes.
{"title":"COVID-19 infection and return-to-play outcomes of elite athletes in Japan: a retrospective descriptive study.","authors":"Kazutaka Fukushima, Kazuyuki Kamahara, Anna Tomori, Yoshio Nakata","doi":"10.1136/bmjsem-2025-002731","DOIUrl":"10.1136/bmjsem-2025-002731","url":null,"abstract":"<p><strong>Objectives: </strong>To describe the characteristics of COVID-19 among elite Japanese athletes and their return-to-play (RTP) time.</p><p><strong>Methods: </strong>We retrospectively reviewed clinical records at the Japan Institute of Sports Sciences between June 2022 and May 2023. Elite athletes who underwent periodic health examinations were examined by a physician to confirm COVID-19 history, symptoms and the RTP time.</p><p><strong>Results: </strong>Of 994 athletes, 456 had a COVID-19 history (mean±SD, 23.3±4.6 years; 56% male). Most infections occurred during the sixth wave (Omicron variant), followed by the seventh and eighth waves, with 88% recorded after the fifth wave. Indoor athletes were more frequently affected than outdoor athletes (306 vs 150, p<0.05). Badminton athletes were the most commonly affected athletes (16%), followed by volleyball (10%) and handball (7%). Among those with a history of COVID-19, 89% reported symptoms, while 11% were asymptomatic. Fever was the most common symptom (80%), followed by sore throat (58%) and cough (44%). The median (IQR) RTP time was 10 (7-14) days. Overall, 472 athletes resumed play within 28 days, while 20 returned after 28 days. RTP delays were more frequent before Omicron (9/59 athletes) than after (11/433 athletes, p<0.05).</p><p><strong>Conclusion: </strong>COVID-19 was more common among indoor sports athletes, primarily during the Omicron wave, with most cases being symptomatic but resolving quickly. These findings likely reflect factors such as close-contact training, immune changes during intensive training and international travel and may help characterise COVID-19 outcomes in elite athletes.</p>","PeriodicalId":47417,"journal":{"name":"BMJ Open Sport & Exercise Medicine","volume":"11 4","pages":"e002731"},"PeriodicalIF":3.2,"publicationDate":"2025-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12574401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-16eCollection Date: 2025-01-01DOI: 10.1136/bmjsem-2025-002724
Jan Ekstrand, Vanna Roos, Anna Hallén, Katrine Okholm Kryger, Håkan Bengtsson
Objectives: Our aim was to describe the absence days caused by the 30 most frequent injury diagnoses in elite European women's club football.
Methods: Members of the medical staff in football clubs participating in the Union of European Football Associations (UEFA) Women's Elite Club Injury Study (WECIS) reported injury occurrences from a total of 72 team-seasons. Injury absence was defined as the number of days between injury occurrence and when the injured player was allowed to return to full participation by the medical team.
Results: In total, 2 390 injuries were registered and included in the study. Sixty-six per cent of these injuries were included among the 30 most common injury diagnoses. Most of the injuries included among the 30 most common were mild leading to a median absence of 7 days or less in 397 cases (23%) or moderate leading to a median absence of 7-28 days in 1177 cases (69%). Severe injuries accounted for a median absence of ≥28 days in 140 cases (8%) were less common and included only four diagnoses, all related to knee injuries. These four diagnoses, however, caused 35% of all absence during the study period.
Conclusion: Most of the time lost due to injuries in elite European women's football teams results from moderate and severe injuries. This article provides guidelines for expected time-loss for the most common injury types in women's professional football and will aid clinicians to make more accurate estimations of when players can be expected to return to participation following injuries.
{"title":"Return to play time for the 30 most common injuries in the UEFA Women's Elite Club Injury Study.","authors":"Jan Ekstrand, Vanna Roos, Anna Hallén, Katrine Okholm Kryger, Håkan Bengtsson","doi":"10.1136/bmjsem-2025-002724","DOIUrl":"10.1136/bmjsem-2025-002724","url":null,"abstract":"<p><strong>Objectives: </strong>Our aim was to describe the absence days caused by the 30 most frequent injury diagnoses in elite European women's club football.</p><p><strong>Methods: </strong>Members of the medical staff in football clubs participating in the Union of European Football Associations (UEFA) Women's Elite Club Injury Study (WECIS) reported injury occurrences from a total of 72 team-seasons. Injury absence was defined as the number of days between injury occurrence and when the injured player was allowed to return to full participation by the medical team.</p><p><strong>Results: </strong>In total, 2 390 injuries were registered and included in the study. Sixty-six per cent of these injuries were included among the 30 most common injury diagnoses. Most of the injuries included among the 30 most common were mild leading to a median absence of 7 days or less in 397 cases (23%) or moderate leading to a median absence of 7-28 days in 1177 cases (69%). Severe injuries accounted for a median absence of ≥28 days in 140 cases (8%) were less common and included only four diagnoses, all related to knee injuries. These four diagnoses, however, caused 35% of all absence during the study period.</p><p><strong>Conclusion: </strong>Most of the time lost due to injuries in elite European women's football teams results from moderate and severe injuries. This article provides guidelines for expected time-loss for the most common injury types in women's professional football and will aid clinicians to make more accurate estimations of when players can be expected to return to participation following injuries.</p>","PeriodicalId":47417,"journal":{"name":"BMJ Open Sport & Exercise Medicine","volume":"11 4","pages":"e002724"},"PeriodicalIF":3.2,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12542716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145356549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-15eCollection Date: 2025-01-01DOI: 10.1136/bmjsem-2024-002346
Saurav Kataria, Harriet Mellor, Stephen P Bird, Peter Thain, Mark Williams, Tom Cresswell, Andy Howse, Camilla Nykjaer, Dane Vishnubala
Objectives: To describe injury epidemiology in British basketball, assess sex-based differences and injury risk factors.
Methods: 122 athletes from British basketball leagues and national teams completed an online questionnaire collecting demographic, sporting and injury data from the 2021/2022 season. A medical-attention and 24-hour time-loss injury definition was used. Injury incidence rate (IIR) (injuries/1000 athlete-exposure (AE) hours) was calculated as (number of injuries/season AE-hours)×1000. Mann-Whitney tests assessed sex differences in IIRs. Χ2 tests assessed sex differences in injury proportions. Linear regression assessed relationships between IIR and reported risk factors.
Results: 46 men and 76 women (median age (IQR): 23.0 years (19.0-26.0)) reported 140 injuries. Median IIR was 2.1 injuries/1000 AE-hours (IQR: 0.0-3.5). Lower limb injuries were most common (70.7%), specifically ankle (32.9%) and knee (25.7%). No significant sex differences were noted in injury site, type, mechanism, timing or severity. Higher IIR was associated with advancing age (B=0.182, 95% CI: 0.038 to 0.325, p=0.014), increased weight (B=0.140, 95% CI: 0.071 to 0.210, p≤0.001), female sex (B=2.214, 95% CI: 0.424 to 4.003, p=0.016), comorbidities (B=2.782, 95% CI: 0.967 to 4.598, p=0.003) and 1-3 years of elite experience (B=2.950, 95% CI: 1.561 to 4.340, p≤0.001 vs 3-8 years). Guards (B=4.996, 95% CI: 3.603 to 6.389, p≤0.001) and forwards (B=3.180, 95% CI: 1.627 to 4.732, p≤0.001) were associated with higher IIR than centres.
Conclusion: Lower limb injuries were most common. IIR was positively associated with age, weight, female sex, comorbidities and 1-3 years of elite experience. Guards and forwards had the strongest associations compared with centres. Findings may inform targeted injury prevention strategies. Future research should prospectively assess injury risk.
{"title":"Epidemiology of injuries in British basketball: a retrospective cross-sectional study.","authors":"Saurav Kataria, Harriet Mellor, Stephen P Bird, Peter Thain, Mark Williams, Tom Cresswell, Andy Howse, Camilla Nykjaer, Dane Vishnubala","doi":"10.1136/bmjsem-2024-002346","DOIUrl":"10.1136/bmjsem-2024-002346","url":null,"abstract":"<p><strong>Objectives: </strong>To describe injury epidemiology in British basketball, assess sex-based differences and injury risk factors.</p><p><strong>Methods: </strong>122 athletes from British basketball leagues and national teams completed an online questionnaire collecting demographic, sporting and injury data from the 2021/2022 season. A medical-attention and 24-hour time-loss injury definition was used. Injury incidence rate (IIR) (injuries/1000 athlete-exposure (AE) hours) was calculated as (number of injuries/season AE-hours)×1000. Mann-Whitney tests assessed sex differences in IIRs. Χ<sup>2</sup> tests assessed sex differences in injury proportions. Linear regression assessed relationships between IIR and reported risk factors.</p><p><strong>Results: </strong>46 men and 76 women (median age (IQR): 23.0 years (19.0-26.0)) reported 140 injuries. Median IIR was 2.1 injuries/1000 AE-hours (IQR: 0.0-3.5). Lower limb injuries were most common (70.7%), specifically ankle (32.9%) and knee (25.7%). No significant sex differences were noted in injury site, type, mechanism, timing or severity. Higher IIR was associated with advancing age (B=0.182, 95% CI: 0.038 to 0.325, p=0.014), increased weight (B=0.140, 95% CI: 0.071 to 0.210, p≤0.001), female sex (B=2.214, 95% CI: 0.424 to 4.003, p=0.016), comorbidities (B=2.782, 95% CI: 0.967 to 4.598, p=0.003) and 1-3 years of elite experience (B=2.950, 95% CI: 1.561 to 4.340, p≤0.001 vs 3-8 years). Guards (B=4.996, 95% CI: 3.603 to 6.389, p≤0.001) and forwards (B=3.180, 95% CI: 1.627 to 4.732, p≤0.001) were associated with higher IIR than centres.</p><p><strong>Conclusion: </strong>Lower limb injuries were most common. IIR was positively associated with age, weight, female sex, comorbidities and 1-3 years of elite experience. Guards and forwards had the strongest associations compared with centres. Findings may inform targeted injury prevention strategies. Future research should prospectively assess injury risk.</p>","PeriodicalId":47417,"journal":{"name":"BMJ Open Sport & Exercise Medicine","volume":"11 4","pages":"e002346"},"PeriodicalIF":3.2,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12530424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145330512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a global health issue due to its high prevalence, yet the impact of accelerometer-measured physical activity on clinical outcomes remains unclear. This study aims to examine the associations of physical activity with the risk of liver cirrhosis, cancer, cardiovascular disease (CVD) incidence and mortality.
Methods: 32 681 MASLD participants with accelerometer-derived physical activity data from the UK Biobank were analysed. Physical activity intensity was categorised into light (LPA), moderate (MPA) and vigorous (VPA) intensity. Cox proportional hazard and acceleration failure models were employed to assess associations between physical activity duration and outcomes.
Results: During a median follow-up of 7.5-7.9 years, 1883 deaths, 151 liver cirrhosis, 3312 cancers and 6657 CVD events were recorded. Physical activity, regardless of intensity, was consistently associated with a reduced risk of liver cirrhosis, CVD and all-cause mortality. Compared with non-MASLD individuals, our analysis indicates that longer duration of physical activity, specifically >1945 min/week of LPA or >383 min/week of MPA may theoretically eliminate the excess risk of mortality associated with MASLD.
Conclusions: Among MASLD individuals, longer physical activity duration, regardless of intensity, was associated with reduced risks of liver cirrhosis and mortality. MPA and VPA were associated with lower CVD risk, while VPA was associated with reduced cancer risk, highlighting the potential benefits of increasing the intensity and duration of physical activity in MASLD management.
{"title":"Physical activity and the risk of cardiovascular disease, cirrhosis, cancer and mortality among individuals with MASLD: a prospective cohort study.","authors":"Sihua Xu, Yiyuan Xiao, Chaoyu Xu, Xiaoya Zeng, Liangyu Zhao, Tuojian Li, Deke Jiang, Rong Na, Haitao Chen","doi":"10.1136/bmjsem-2025-002702","DOIUrl":"10.1136/bmjsem-2025-002702","url":null,"abstract":"<p><strong>Objectives: </strong>Metabolic dysfunction-associated steatotic liver disease (MASLD) is a global health issue due to its high prevalence, yet the impact of accelerometer-measured physical activity on clinical outcomes remains unclear. This study aims to examine the associations of physical activity with the risk of liver cirrhosis, cancer, cardiovascular disease (CVD) incidence and mortality.</p><p><strong>Methods: </strong>32 681 MASLD participants with accelerometer-derived physical activity data from the UK Biobank were analysed. Physical activity intensity was categorised into light (LPA), moderate (MPA) and vigorous (VPA) intensity. Cox proportional hazard and acceleration failure models were employed to assess associations between physical activity duration and outcomes.</p><p><strong>Results: </strong>During a median follow-up of 7.5-7.9 years, 1883 deaths, 151 liver cirrhosis, 3312 cancers and 6657 CVD events were recorded. Physical activity, regardless of intensity, was consistently associated with a reduced risk of liver cirrhosis, CVD and all-cause mortality. Compared with non-MASLD individuals, our analysis indicates that longer duration of physical activity, specifically >1945 min/week of LPA or >383 min/week of MPA may theoretically eliminate the excess risk of mortality associated with MASLD.</p><p><strong>Conclusions: </strong>Among MASLD individuals, longer physical activity duration, regardless of intensity, was associated with reduced risks of liver cirrhosis and mortality. MPA and VPA were associated with lower CVD risk, while VPA was associated with reduced cancer risk, highlighting the potential benefits of increasing the intensity and duration of physical activity in MASLD management.</p>","PeriodicalId":47417,"journal":{"name":"BMJ Open Sport & Exercise Medicine","volume":"11 4","pages":"e002702"},"PeriodicalIF":3.2,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12519692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145303969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-13eCollection Date: 2025-01-01DOI: 10.1136/bmjsem-2025-002678
Leonard Tanko Tankeng, Christian Eyoum, Gilbert Mua Akwa, Randol Tsowa Vouomene, Veronique Ange Ngo Bilong, Livingstone Dziany, Narcisse Tinkeu, Maurice Douryang
Objectives: To assess the mental health status of referees in Cameroonian professional football and identify associated risk factors.
Methods: A cross-sectional analytical study was conducted among referees from the Cameroon Elite One, Elite Two and Female Super League during the 2024-2025 season. The Depression Anxiety Stress Scale-21 was used to assess mental health status after officiating a match, classifying scores as normal, mild, moderate, severe or extremely severe for depression, anxiety and stress symptoms. Data were analysed using R Studio (V.4.2.2). Logistic regression identified associations with statistical significance set at p<0.05.
Results: Out of 179 professional referees in Cameroon, 150 (83.8%) participated. Ages ranged from 18 to 45 years (mean=30±5.86 years). Depression symptoms were observed in 28%, with higher rates in assistant referees (32.4%) than in central referees (23.7%). Anxiety symptoms were present in 42.7% of participants, while 12% exhibited stress symptoms. Lower level referees had higher levels of all symptoms. Notably, 90.5% of referees with symptoms of depression had at least one additional mental health symptom. Severe symptoms of depression co-occurred with severe anxiety and stress symptoms. Having another profession significantly increased risks of depression symptoms (p=0.007, OR 7.7) and anxiety (p=0.003, OR 4.2). Performance concerns were the main psychological stressor (74.0%).
Conclusion: Cameroonian referees experience high levels of depression, anxiety and stress symptoms, with assistant referees more affected. Holding another profession increases mental health risks. Targeted interventions are needed to address psychological stressors and improve referees' well-being.
目的:评估喀麦隆职业足球裁判的心理健康状况,并确定相关的危险因素。方法:对喀麦隆英甲联赛、英甲联赛和女超联赛2024-2025赛季裁判进行横断面分析研究。使用抑郁焦虑压力量表-21来评估裁判比赛后的心理健康状况,将抑郁、焦虑和压力症状分为正常、轻度、中度、重度或极重度。数据分析使用R Studio (V.4.2.2)。逻辑回归在结果中确定了具有统计学显著性的关联:在喀麦隆的179名专业裁判中,150名(83.8%)参与了调查。年龄18 ~ 45岁,平均30±5.86岁。有抑郁症状者占28%,其中助理裁判(32.4%)高于中央裁判(23.7%)。42.7%的参与者出现焦虑症状,12%的参与者表现出压力症状。水平较低的裁判的所有症状水平较高。值得注意的是,90.5%有抑郁症状的裁判至少有一种额外的心理健康症状。严重的抑郁症状与严重的焦虑和压力症状同时发生。拥有其他职业显著增加抑郁症状(p=0.007, OR 7.7)和焦虑(p=0.003, OR 4.2)的风险。表现担忧是主要的心理压力源(74.0%)。结论:喀麦隆裁判经历了高度的抑郁、焦虑和压力症状,助理裁判受到的影响更大。从事其他职业会增加心理健康风险。需要有针对性的干预措施来解决心理压力源,提高裁判的幸福感。
{"title":"Mental health of professional football referees in Cameroon: exploring challenges and developing support interventions.","authors":"Leonard Tanko Tankeng, Christian Eyoum, Gilbert Mua Akwa, Randol Tsowa Vouomene, Veronique Ange Ngo Bilong, Livingstone Dziany, Narcisse Tinkeu, Maurice Douryang","doi":"10.1136/bmjsem-2025-002678","DOIUrl":"10.1136/bmjsem-2025-002678","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the mental health status of referees in Cameroonian professional football and identify associated risk factors.</p><p><strong>Methods: </strong>A cross-sectional analytical study was conducted among referees from the Cameroon Elite One, Elite Two and Female Super League during the 2024-2025 season. The Depression Anxiety Stress Scale-21 was used to assess mental health status after officiating a match, classifying scores as normal, mild, moderate, severe or extremely severe for depression, anxiety and stress symptoms. Data were analysed using R Studio (V.4.2.2). Logistic regression identified associations with statistical significance set at p<0.05.</p><p><strong>Results: </strong>Out of 179 professional referees in Cameroon, 150 (83.8%) participated. Ages ranged from 18 to 45 years (mean=30±5.86 years). Depression symptoms were observed in 28%, with higher rates in assistant referees (32.4%) than in central referees (23.7%). Anxiety symptoms were present in 42.7% of participants, while 12% exhibited stress symptoms. Lower level referees had higher levels of all symptoms. Notably, 90.5% of referees with symptoms of depression had at least one additional mental health symptom. Severe symptoms of depression co-occurred with severe anxiety and stress symptoms. Having another profession significantly increased risks of depression symptoms (p=0.007, OR 7.7) and anxiety (p=0.003, OR 4.2). Performance concerns were the main psychological stressor (74.0%).</p><p><strong>Conclusion: </strong>Cameroonian referees experience high levels of depression, anxiety and stress symptoms, with assistant referees more affected. Holding another profession increases mental health risks. Targeted interventions are needed to address psychological stressors and improve referees' well-being.</p>","PeriodicalId":47417,"journal":{"name":"BMJ Open Sport & Exercise Medicine","volume":"11 4","pages":"e002678"},"PeriodicalIF":3.2,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12519685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}