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Effects of dry needling on spasticity and motor function in paralympic athletes: a study protocol for a randomised controlled trial. 干针疗法对残奥运动员痉挛和运动功能的影响:随机对照试验研究方案。
IF 3.9 Q1 SPORT SCIENCES Pub Date : 2024-06-25 eCollection Date: 2024-01-01 DOI: 10.1136/bmjsem-2024-002096
Fatemeh Aliasgharpour, Roshanak Honarpishe, Seyed Hossein Hosseini-Asl, Mohammad Saeid Khonji, Faezeh Abbaschian, Noureddin Nakhostin Ansari, Soofia Naghdi, Pablo Herrero Gallego, Amin Nakhostin-Ansari

No study has evaluated the effects of dry needling on Paralympic athletes. Therefore, in this study, we will evaluate the effect of dry needling on lower limb spasticity and motor performance, as well as the range of motion of Paralympic athletes. The study will be a triple-blinded, randomised controlled trial. Twenty-four athletes aged 18-45 in T35-T38 groups of the International Paralympic Committee classification will be included in the study. Twelve participants will receive dry needling of the quadriceps and gastrocnemius muscles, and 12 will receive placebo treatment with sham needles at similar points. We will assess the spasticity of the quadriceps and gastrocnemius muscles using the Modified Ashworth Scale, evaluate motor function using the Selective Control Assessment of the Lower Extremity Scale and measure ankle range of motion (ROM) with a goniometer. Considering our hypothesis, the athletes who will undergo the dry needling are supposed to achieve better improvements in spasticity, ROM and motor performance. This study can provide useful information to help better decide on managing complications in Paralympics and its long-term outcomes, to cover the current lack in the literature.

目前还没有研究评估干针疗法对残奥运动员的影响。因此,在这项研究中,我们将评估干针疗法对残奥运动员下肢痉挛、运动表现以及运动范围的影响。这项研究将是一项三盲随机对照试验。24 名年龄在 18-45 岁之间、属于国际残奥委员会分类中 T35-T38 组别的运动员将参加这项研究。12 名参与者将接受股四头肌和腓肠肌干针疗法,12 名参与者将在类似穴位接受假针安慰剂治疗。我们将使用 "改良阿什沃斯量表 "评估股四头肌和腓肠肌的痉挛程度,使用 "下肢选择性控制评估量表 "评估运动功能,并使用动态关节角度计测量踝关节的活动范围(ROM)。根据我们的假设,接受干针疗法的运动员在痉挛、活动范围和运动表现方面应该会有更好的改善。这项研究可以提供有用的信息,帮助更好地决定如何处理残奥会并发症及其长期结果,弥补目前文献中的不足。
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引用次数: 0
Shedding light on the non-operative treatment of the forgotten side of the knee: rehabilitation of medial collateral ligament injuries-a systematic review. 揭示膝关节被遗忘一侧的非手术治疗:内侧副韧带损伤的康复--系统综述。
IF 3.9 Q1 SPORT SCIENCES Pub Date : 2024-06-25 eCollection Date: 2024-01-01 DOI: 10.1136/bmjsem-2023-001750
Jasmine Svantesson, Ramana Piussi, Elin Weissglas, Eleonor Svantesson, Alexandra Horvath, Erik Börjesson, Andy Williams, Robert Prill, Kristian Samuelsson, Eric Hamrin Senorski

Objective: The purpose of this study was to review the current literature regarding the non-operative treatment of isolated medial collateral ligament (MCL) injuries.

Design: Systematic review, registered in the Open Science Framework (https://doi.org/10.17605/OSF.IO/E9CP4).

Data sources: The Embase, MEDLINE and PEDro databases were searched; last search was performed on December 2023.

Eligibility criteria: Peer-reviewed original reports from studies that included information about individuals who sustained an isolated MCL injury with non-surgical treatment as an intervention, or reports comparing surgical with non-surgical treatment were eligible for inclusion. Included reports were synthesised qualitatively. Risk of bias was assessed with the Risk of Bias Assessment tool for Non-randomized Studies. Certainty of evidence was determined using the Grading of Recommendations Assessment Development and Evaluation.

Results: A total of 26 reports (1912 patients) were included, of which 18 were published before the year 2000 and 8 after. No differences in non-operative treatment were reported between grade I and II injuries, where immediate weight bearing and ambulation were tolerated, and rehabilitation comprised different types of strengthening exercises with poorly reported details. Some reports used immobilisation with a brace as a treatment method, while others did not use any equipment. The use of a brace and duration of use was inconsistently reported.

Conclusion: There is substantial heterogeneity and lack of detail regarding the non-operative treatment of isolated MCL injuries. This should prompt researchers and clinicians to produce high-quality evidence studies on the promising non-operative treatment of isolated MCL injuries to aid in decision-making and guide rehabilitation after MCL injury.

Level of evidence: Level I, systematic review.

研究目的本研究旨在回顾有关孤立性内侧副韧带(MCL)损伤非手术治疗的现有文献:数据来源:Embase、MEDLINE 和 PEDro:检索了 Embase、MEDLINE 和 PEDro 数据库;最后一次检索于 2023 年 12 月进行:经同行评议的原始研究报告符合纳入条件,这些报告包括以非手术治疗为干预措施的孤立性 MCL 损伤患者的相关信息,或比较手术与非手术治疗的报告。对纳入的报告进行定性综合。采用非随机研究偏倚风险评估工具对偏倚风险进行评估。证据的确定性采用建议分级评估发展和评价法来确定:共纳入 26 篇报告(1912 名患者),其中 18 篇发表于 2000 年之前,8 篇发表于 2000 年之后。I级和II级损伤的非手术治疗方法没有差异,均可立即负重和下地行走,康复治疗包括不同类型的强化训练,但详细报道较少。一些报告使用支架固定作为治疗方法,而另一些报告则不使用任何设备。关于支具的使用和持续时间的报道也不一致:结论:关于孤立性 MCL 损伤的非手术治疗存在很大的异质性,且缺乏细节。这应促使研究人员和临床医生就有希望的孤立性 MCL 损伤非手术治疗方法进行高质量的证据研究,以帮助决策并指导 MCL 损伤后的康复:证据级别:I级,系统综述。
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引用次数: 0
Players are positive regarding injury prevention exercise programmes, but coaches need ongoing support: a survey-based evaluation using the Health Action Process Approach model across one season in amateur and youth football. 球员对预防受伤运动计划持积极态度,但教练需要持续支持:在业余足球和青少年足球的一个赛季中,采用健康行动过程方法模式进行的一项基于调查的评估。
IF 3.9 Q1 SPORT SCIENCES Pub Date : 2024-06-24 eCollection Date: 2024-01-01 DOI: 10.1136/bmjsem-2024-002009
Hanna Lindblom, Ida Åkerlund, Markus Waldén, Sofi Sonesson, Martin Hägglund

Objectives: Implementation of injury prevention exercise programmes (IPEPs) in sports is challenging, and behaviour change among players and coaches is essential for success. The aim was to describe players' and coaches' motivation and coaches' goal pursuit when using IPEPs in amateur and youth football across a season. A secondary aim was to describe players' motivation to engage in IPEP use in relation to presence or absence of injury.

Methods: The study was based on questionnaires to amateur and youth, male and female football players and coaches at baseline, mid-season and post-season in a three-armed randomised trial in 2020 in Sweden. Questionnaires were based on the Health Action Process Approach (HAPA) model with questions about the motivational phase when intention for change is created (players and coaches) and a goal-pursuit phase when intention is translated into action (coaches).

Results: In total, 455 players (126 male), mean age 20.1 years (SD±5.8, range 14-46) and 59 (52 male) coaches took part. Players generally gave positive answers in the HAPA motivational phase (Likert 6-7 on a 1-7 Likert scale). Differences in ratings between injured and uninjured players were minor. Coaches had positive or neutral ratings (Likert 4-6) in the motivational and goal-pursuit phases. Ratings deteriorated across the season, with less positive responses from 40% of players and 38-46% of coaches post-season.

Conclusion: Positive ratings in the HAPA motivational phase indicated fertile ground for IPEP use. Neutral ratings by coaches and deterioration across the season in players and coaches suggest a need for ongoing support for IPEP use.

Trial registration number: NCT04272047.

目标:在体育运动中实施损伤预防运动计划(IPEP)具有挑战性,球员和教练员的行为改变是成功的关键。本研究旨在描述业余和青少年足球运动员和教练员在整个赛季中使用 IPEP 时的动机和目标追求。次要目的是描述球员使用 IPEP 的动机与是否受伤的关系:研究基于 2020 年在瑞典进行的一项三臂随机试验中对业余和青少年、男性和女性足球运动员和教练员在基线、赛季中期和赛季后进行的问卷调查。问卷以健康行动过程方法(HAPA)模型为基础,问题涉及产生改变意愿的动机阶段(球员和教练)以及将意愿转化为行动的目标追求阶段(教练):共有 455 名球员(126 名男性)(平均年龄 20.1 岁,SD±5.8,14-46 岁不等)和 59 名教练(52 名男性)参加了问卷调查。在 HAPA 激励阶段,球员们普遍给出了积极的答案(李克特量表为 6-7,1-7 分)。受伤球员和未受伤球员的评分差异不大。教练在激励和目标追求阶段的评分为正面或中性(Likert 4-6)。赛季结束后,40% 的球员和 38-46% 的教练的积极评价有所下降:结论:HAPA激励阶段的积极评价是使用IPEP的沃土。教练的中性评价以及球员和教练在整个赛季中的评价下降表明,需要为 IPEP 的使用提供持续支持:NCT04272047.
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引用次数: 0
'I want to ski and race, not just ski': a qualitative study on athletes' and stakeholders' perspectives on return-to-sport in high-performance Snowsports. 我想滑雪和比赛,而不仅仅是滑雪":关于运动员和利益相关者对重返高性能雪上运动的看法的定性研究。
IF 3.9 Q1 Health Professions Pub Date : 2024-06-21 eCollection Date: 2024-01-01 DOI: 10.1136/bmjsem-2024-001967
Philippe O Müller, Moritz Helbling, Evert Verhagen, Jörg Spörri, Caroline Bolling

This study explored stakeholders' perspectives on current practices, challenges and opportunities related to the return-to-sport (RTS) process in high-performance Snowsports. We conducted fourteen semi-structured interviews with athletes, coaches and health professionals from multiple countries using online video platforms. The data were transcribed verbatim and analysed based on constant comparative analysis employing the principles of Grounded Theory. Codes were grouped into categories and main concepts and a conceptual model were derived. According to the participants, RTS should be considered a continuous process to bring the athlete back to competition as fast and safely as possible, whereas speed is often prioritised over safety. Participants described the need for a structured and criteria-based process. Despite the multiple phases and the diversity of involved professionals, the process is individualised and unique, highlighting the value of having the athlete at the centre of the RTS process. It was considered essential to provide a safe environment and build trustworthy relationships. Additionally, access to resources, communication and cooperation among all experts was perceived as critical to successful RTS. Our participants described the value of continuity and an athlete-centred approach to the RTS process. The challenges, such as interprofessional communication, the lack of objective sport-specific criteria, and the diversity of resources and network structures, were perceived as practical issues that influenced the process, which should be tailored for each athlete accordingly to reach a successful RTS.

本研究探讨了利益相关者对高性能雪上运动中重返运动场(RTS)过程的当前实践、挑战和机遇的看法。我们利用在线视频平台对来自多个国家的运动员、教练员和保健专业人员进行了 14 次半结构式访谈。数据被逐字转录,并根据基础理论的原则进行不断比较分析。对代码进行了分类,并得出了主要概念和概念模型。参与者认为,康复训练应被视为一个持续的过程,使运动员尽可能快地、安全地重返赛场,而速度往往比安全更重要。与会者指出,需要有一个结构化的、基于标准的过程。尽管有多个阶段和不同的专业人员参与,但这一过程是个性化和独特的,突出了以运动员为中心的康复治疗过程的价值。提供安全的环境和建立值得信赖的关系被认为是至关重要的。此外,所有专家之间的资源获取、沟通与合作被认为是成功开展康复治疗服务的关键。我们的参与者描述了连续性和以运动员为中心的方法对研究与培训进程的价值。跨专业交流、缺乏针对特定运动的客观标准以及资源和网络结构的多样性等挑战被认为是影响这一过程的实际问题,应根据每位运动员的具体情况进行相应调整,以实现成功的康复治疗。
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引用次数: 0
Establishment of clinical exercise physiology as a regulated healthcare profession in the UK: a progress report. 在英国将临床运动生理学确立为受监管的医疗保健专业:进展报告。
IF 3.9 Q1 Health Professions Pub Date : 2024-06-18 eCollection Date: 2024-01-01 DOI: 10.1136/bmjsem-2024-002033
Helen Jones, Anthony Crozier, Keith George, Gemma Miller, Greg P Whyte, Joanna Rycroft, Andrew Scott, John P Buckley, Gordon McGregor, Christopher David Askew, Sandy Jack, Steffan Birkett, David R Broom, Keith Tolfrey, Anna Campbell, Dawn A Skelton, Lizanne Steenkamp, Jude Savage, Daniel J Green

In 2021, a 'call to action' was published to highlight the need for professional regulation of clinical exercise physiologists to be established within UK healthcare systems to ensure patient safety and align training and regulation with other health professions. This manuscript provides a progress report on the actions that Clinical Exercise Physiology UK (CEP-UK) has undertaken over the past 4 years, during which time clinical exercise physiologists have implemented regulation and gained formal recognition as healthcare professionals in the UK. An overview of the consultation process involved in creating a regulated health profession, notably the development of policies and procedures for both individual registration and institutional master's degree (MSc) accreditation is outlined. Additionally, the process for developing an industry-recognised scope of practice, a university MSc-level curriculum framework, the Academy for Healthcare Science Practitioner standards of proficiency and Continuing Professional Development opportunities is included. We outline the significant activities and milestones undertaken by CEP-UK and provide insight and clarity for other health professionals to understand the training and registration process for a clinical exercise physiologist in the UK. Finally, we include short, medium and long-term objectives for the future advocacy development of this workforce in the UK.

2021 年,英国发布了一份 "行动呼吁",强调有必要在英国医疗系统内建立临床运动生理学家的专业监管,以确保患者安全,并使培训和监管与其他医疗专业保持一致。本手稿就英国临床运动生理学协会(CEP-UK)在过去 4 年中采取的行动提供了一份进展报告,在此期间,英国临床运动生理学协会已实施了监管,并获得了英国医疗保健专业人士的正式认可。本文概述了创建受监管的健康专业所涉及的咨询过程,特别是个人注册和机构硕士学位 (MSc) 认证的政策和程序的制定过程。此外,还包括制定行业认可的实践范围、大学硕士课程框架、医疗保健科学从业人员学院能力标准和继续职业发展机会的过程。我们概述了英国临床运动生理学家协会开展的重要活动和取得的里程碑式成果,并为其他医疗专业人士提供了深入的见解和清晰的思路,帮助他们了解英国临床运动生理学家的培训和注册流程。最后,我们还列出了英国该职业队伍未来宣传发展的短期、中期和长期目标。
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引用次数: 0
Heavy resistance training at retirement age induces 4-year lasting beneficial effects in muscle strength: a long-term follow-up of an RCT. 退休年龄进行大强度阻力训练可在 4 年内对肌肉力量产生持久的有益影响:一项 RCT 的长期跟踪研究。
IF 3.9 Q1 Health Professions Pub Date : 2024-06-18 eCollection Date: 2024-01-01 DOI: 10.1136/bmjsem-2024-001899
Mads Bloch-Ibenfeldt, Anne Theil Gates, Karoline Karlog, Naiara Demnitz, Michael Kjaer, Carl-Johan Boraxbekk

Objectives: Muscle function and size decline with age, but long-term effects of resistance training in older adults are largely unknown. Here, we explored the long-lasting (3 years) effects of 1 year of supervised resistance training with heavy loads.

Methods: The LIve active Successful Ageing (LISA) study was a parallel group randomised controlled trial at a university hospital in Denmark. Older adults (n=451) at retirement age were randomised to 1 year of heavy resistance training (HRT), moderate-intensity training (MIT) or a non-exercising control group (CON). Primary outcome measure was leg extensor power. Secondary outcomes included maximal isometric quadriceps torque (isometric leg strength) and body composition (dual-energy X-ray absorptiometry (DXA)). Participants completed test procedures at baseline, following the 1-year intervention, and 2 and 4 years post study start.

Results: At the 4-year assessment, 369 participants attended (mean age=71 years, 61% women). The main finding was that across all four time points, there was a significant group×time interaction in isometric leg strength (F6,1049=8.607, p<0.001, η 2 =0.05). Individuals in HRT maintained baseline performance in isometric leg strength (Baseline: 149.7±51.5 Nm, 4 years: 151.5±51.1 Nm, t(1050)=1.005, p=1.00) while participants in CON and MIT decreased.

Conclusion: In well-functioning older adults at retirement age, 1 year of HRT may induce long-lasting beneficial effects by preserving muscle function.

Trial registration number: NCT02123641.

目的:肌肉的功能和大小会随着年龄的增长而下降,但阻力训练对老年人的长期影响在很大程度上是未知的。在此,我们探讨了在监督下进行为期一年的大负荷阻力训练的长期(3 年)效果:积极成功老龄化研究(LISA)是在丹麦一所大学医院进行的平行分组随机对照试验。处于退休年龄的老年人(451 人)被随机分配到为期一年的大负荷阻力训练组(HRT)、中等强度训练组(MIT)或非运动对照组(CON)。主要结果指标为腿部伸肌力量。次要结果包括最大等距股四头肌扭矩(等距腿部力量)和身体成分(双能 X 射线吸收测定法(DXA))。参与者在基线、1 年干预后、研究开始后的 2 年和 4 年完成了测试程序:在为期 4 年的评估中,共有 369 人参加(平均年龄为 71 岁,61% 为女性)。主要发现是,在所有四个时间点上,等长腿部力量存在显著的组别×时间交互作用(F6,1049=8.607, p η 2 =0.05)。接受 HRT 的个体保持了等长腿部力量的基线表现(基线:149.7±51.5 牛米,4 年:151.5±51.1 牛米):151.5±51.1牛米,t(1050)=1.005,p=1.00),而CON和MIT的参与者则有所下降:结论:对于处于退休年龄、身体机能良好的老年人,1年的HRT可能会通过保护肌肉功能而产生持久的益处:NCT02123641。
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引用次数: 0
Psychological readiness for injury recovery: evaluating psychometric properties of the IPRRS and assessing group differences in injured physically active individuals. 受伤恢复的心理准备:评估 IPRRS 的心理测量特性,并评估受伤体能活动者的群体差异。
IF 4.8 Q1 Health Professions Pub Date : 2024-06-17 eCollection Date: 2024-01-01 DOI: 10.1136/bmjsem-2023-001869
Alexandra Dluzniewski, Madeline P Casanova, Sarah Ullrich-French, Christopher J Brush, Lindsay W Larkins, Russell T Baker

Objectives: The primary purpose of the study was to assess the one-factor and two-factor structure of the Injury Psychological Readiness to Return to Sport Scale (IPRRS) in an injured physically active population using confirmatory factor analysis (CFA) procedures and assess group (ie, sex, age, injury type, athlete status) and longitudinal differences using structural equation modelling (eg, invariance testing).

Methods: The non-experimental study included a sample of 629 physically active individuals who suffered a musculoskeletal injury who sought treatment at an outpatient integrated sport medicine and rehabilitation therapy clinic. Participants filled out a questionnaire packet at three time points. Data analysis included a CFA and multigroup and longitudinal invariance.

Results: Sample mean age was 26.3 years, with females comprising 49.5%. Chronic injuries represented 29.6% of the sample and 35.0% were classified as competitive athletes. A six-item, one-factor model was confirmed in the sample with factor loadings ranging from 0.67 to 0.86. Multigroup and longitudinal invariance were established. Multigroup invariance demonstrated null differences between sex and injury type, and statistical differences between age and athlete status subgroups. Longitudinal invariance demonstrated a statistically significant increase in psychological readiness over time.

Conclusions: The findings support the use of the IPRRS as a tool to measure aspects of psychological readiness. Clinicians and researchers can use the IPRRS to assess interventions in future research.

研究目的本研究的主要目的是利用确证因子分析(CFA)程序,评估体力活动受伤人群的 "重返运动损伤心理准备量表"(IPRRS)的单因子和双因子结构,并利用结构方程建模(如不变量测试)评估群体(即性别、年龄、损伤类型、运动员状态)和纵向差异:这项非实验研究的样本包括 629 名在综合运动医学和康复治疗门诊接受治疗的肌肉骨骼损伤患者。参与者在三个时间点填写了调查问卷。数据分析包括 CFA 和多组及纵向不变量分析:样本平均年龄为 26.3 岁,女性占 49.5%。慢性损伤占样本的 29.6%,35.0% 属于竞技运动员。在样本中确认了一个由六个项目组成的单因子模型,因子载荷在 0.67 至 0.86 之间。多组不变量和纵向不变量均已确定。多组不变量表明,性别和受伤类型之间的差异为零,年龄和运动员身份亚组之间存在统计学差异。纵向不变性表明,随着时间的推移,心理准备度在统计学上有显著提高:研究结果支持使用 IPRRS 作为测量心理准备的工具。临床医生和研究人员可在未来的研究中使用 IPRRS 评估干预措施。
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引用次数: 0
Measure do not guess: a call to action to end assumed and estimated menstrual cycle phases in research. 不要猜测,要测量:呼吁采取行动,结束研究中假定和估计的月经周期阶段。
IF 4.8 Q1 Health Professions Pub Date : 2024-06-17 eCollection Date: 2024-01-01 DOI: 10.1136/bmjsem-2024-002095
Richard J Burden, Marco Altini, Eva Ferrer, Tessa R Flood, Gary Lewin, Sophia Nimphius, Stuart M Phillips, Kirsty J Elliott-Sale
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引用次数: 0
What did we learn about elite student-athlete mental health systems from the COVID-19 pandemic? 我们从 COVID-19 大流行病中学到了哪些关于精英学生运动员心理健康系统的知识?
IF 4.8 Q1 Health Professions Pub Date : 2024-06-17 eCollection Date: 2024-01-01 DOI: 10.1136/bmjsem-2023-001733
Kaitlin Simpson, Graham Baker, Emily Cameron-Blake, Debbie Palmer, Grant Jarvie, Paul Kelly

Elite student-athletes (SAs) in higher education (HE) have distinct mental health (MH) risks. The COVID-19 pandemic put pressure on systems and increased elite SA vulnerability to adverse MH outcomes. The aim of this study was to explore the provision and management of MH in elite HE sports settings during the time of COVID-19 pandemic stress. The secondary aim was to identify lessons and opportunities to enhance future mental healthcare systems and services for elite SAs. A qualitative study design was used to investigate the views of three groups (athletic directors, coaches and sport healthcare providers). Ten key leaders were purposively recruited from HE institutions in Canada, the USA and the United Kingdom. They represented various universities from the National College Athletic Association, U SPORTS Canada and British Universities and Colleges Sport. Semistructured interviews were conducted, recorded, transcribed and thematically analysed. Five key themes were identified: (1) The pandemic disruption had salient impacts on motivation and how elite SAs engaged with sport (2) when student sport systems are under pressure, support staff perceive a change in duties and experience their own MH challenges, (3) the pandemic increased awareness about MH care provision and exposed systemic challenges, (4) digital transformation in MH is complex and has additional challenges for SAs and (5) there were some positive outcomes of the pandemic, lessons learnt and a resulting motivation for systems change. Participants highlighted future opportunities for MH provision in elite university sport settings. Four recommendations were generated from the results.

高等教育(HE)中的精英学生运动员(SAs)有明显的心理健康(MH)风险。COVID-19 大流行对系统造成了压力,并增加了精英体育运动员对不良心理健康后果的脆弱性。本研究的目的是探讨在 COVID-19 大流行的压力下,精英高等教育体育环境中心理健康的提供和管理情况。次要目的是找出经验教训和机遇,以加强未来为精英体育运动员提供的心理保健系统和服务。研究采用定性研究设计,调查三个群体(体育总监、教练和体育保健提供者)的观点。从加拿大、美国和英国的高等院校有目的地招募了 10 名主要领导。他们代表了来自全国大学生体育协会、加拿大 U SPORTS 以及英国大学和学院体育的各所大学。我们进行了半结构式访谈,并对访谈内容进行了记录、转录和主题分析。确定了五个关键主题:(1) 大流行病的破坏对精英体育指导员参与体育运动的动机和方式产生了显著影响,(2) 当学生体育系统面临压力时,辅助人员会感受到职责的变化,并体验到自身在心理健康方面面临的挑战,(3) 大流行病提高了人们对心理健康护理服务的认识,并暴露了系统性挑战,(4) 心理健康方面的数字化转型非常复杂,对体育指导员来说是额外的挑战,(5) 大流行病产生了一些积极的结果,从中吸取了经验教训,并由此产生了系统变革的动力。与会者强调了在精英大学体育环境中提供保健服务的未来机遇。研究结果提出了四项建议。
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引用次数: 0
Cardiac troponin concentrations following exercise and the association with cardiovascular disease and outcomes: rationale and design of the prospective TREAT cohort study. 运动后心肌肌钙蛋白浓度以及与心血管疾病和预后的关系:前瞻性 TREAT 队列研究的原理和设计。
IF 4.8 Q1 Health Professions Pub Date : 2024-06-13 eCollection Date: 2024-01-01 DOI: 10.1136/bmjsem-2024-002070
Sylvan L J E Janssen, Sacha K Lamers, Wim H M Vroemen, Ellen J S Denessen, Kristian Berge, Otto Bekers, Maria T E Hopman, Monique Brink, Jesse Habets, Robin Nijveldt, Wouter M Van Everdingen, Vincent L Aengevaeren, Alma M A Mingels, Thijs M H Eijsvogels

Exercise can produce transient elevations of cardiac troponin (cTn) concentrations, which may resemble the cTn release profile of myocardial infarction. Consequently, clinical interpretation of postexercise cTn elevations (ie, values above the 99th percentile upper reference limit) remains challenging and may cause clinical confusion. Therefore, insight into the physiological versus pathological nature of postexercise cTn concentrations is warranted. We aim to (1) establish resting and postexercise reference values for recreational athletes engaged in walking, cycling or running exercise; (2) compare the prevalence of (sub)clinical coronary artery disease in athletes with high versus low postexercise cTn concentrations and (3) determine the association between postexercise cTn concentrations and the incidence of major adverse cardiovascular events (MACE) and mortality during long-term follow-up. For this purpose, the prospective TRoponin concentrations following Exercise and the Association with cardiovascular ouTcomes (TREAT) observational cohort study was designed to recruit 1500 recreational athletes aged ≥40 to <70 years who will participate in Dutch walking, cycling and running events. Baseline and postexercise high-sensitivity cTnT and cTnI concentrations will be determined. The prevalence and magnitude of coronary atherosclerosis on computed tomography (eg, coronary artery calcium score, plaque type, stenosis degree and CT-derived fractional flow reserve) will be compared between n=100 athletes with high postexercise cTn concentrations vs n=50 age-matched, sex-matched and sport type-matched athletes with low postexercise cTn concentrations. The incidence of MACE and mortality will be assessed in the entire cohort up to 20 years follow-up. The TREAT study will advance our understanding of the clinical significance of exercise-induced cTn elevations in middle-aged and older recreational athletes. Trial registration number NCT06295081.

运动可导致心肌肌钙蛋白(cTn)浓度短暂升高,这可能与心肌梗死的 cTn 释放特征相似。因此,对运动后 cTn 升高(即值超过第 99 百分位数参考上限)的临床解释仍具有挑战性,可能会造成临床混乱。因此,有必要深入了解运动后 cTn 浓度的生理和病理性质。我们的目标是:(1) 为从事步行、骑自行车或跑步运动的休闲运动员建立静息和运动后参考值;(2) 比较运动后 cTn 浓度高与低的运动员中(亚)临床冠状动脉疾病的患病率;(3) 确定运动后 cTn 浓度与长期随访期间主要不良心血管事件(MACE)发生率和死亡率之间的关联。为此,我们设计了前瞻性的运动后促肾上腺皮质激素浓度与心血管事件的关系(TREAT)观察性队列研究,招募了 1500 名年龄≥40 岁的休闲运动员参加,试验注册号为 NCT06295081。
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BMJ Open Sport & Exercise Medicine
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