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Bilateral lipomatous hamartoma of the tongue: A case report in a child with oral-facial-digital syndrome type VI. 双侧舌脂肪瘤:口腔-面部-数字综合征 VI 型患儿的病例报告。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-01-07 DOI: 10.1111/scd.12958
Aline Queiroz, Paulo Sérgio Souza Pina, Myrian Stella Paiva Novaes, Beatriz Dutra, Suzana Cantanhede Orsini Machado de Sousa, Luciane Hiramatsu Azevedo

A hamartoma is a benign proliferation of typical mature cells specific to a particular anatomical site. In the oral cavity, they may occur as isolated cases or be associated with genetic syndromes. Oral-facial-digital syndrome type VI is a rare genetic disorder with an estimated incidence of one in 50,000-250,000 newborns. Here, we report a case of a 2-year-old boy diagnosed with oral-facial-digital syndrome type VI who was referred for evaluation of a bilateral and normochromic to slightly pinkish nodule on the lateral surface of the tongue. Clinically, the child presented hypotonia, low visual acuity, absence of oculocephalic reflex, delay in neuropsychomotor development, and polydactyly in the feet. Excisional biopsies of both sides of the tongue were performed using a 1.5 W high-power diode laser (wavelength of 980 nm), and histopathological analysis revealed abundant mature adipocytes predominantly arranged in lobules that mainly surrounded the minor salivary gland parenchyma. The surgical sites healed with no complications and the patient remains under follow-up for 10 months. Due to the limited literature on this syndrome and the frequent presence of tongue hamartomas in children, dentists need to be familiar with them.

火腿肠瘤是特定解剖部位典型成熟细胞的良性增生。在口腔中,它们可能是孤立的病例,也可能与遗传综合征有关。口腔-面部-数字综合征 VI 型是一种罕见的遗传性疾病,估计发病率为新生儿的五万至二十五万分之一。在此,我们报告了一例被诊断为口腔-面部-数字综合征 VI 型的 2 岁男孩,他因舌头外侧表面出现双侧正常色素至略带粉红色结节而转诊。临床表现为肌张力低下、视力低下、眼脑反射缺失、神经心理运动发育迟缓、双脚多指。使用 1.5 W 高功率二极管激光器(波长 980 nm)对两侧舌头进行了切除活检,组织病理学分析显示,大量成熟的脂肪细胞主要呈小叶状排列,主要围绕着小唾液腺实质。手术部位愈合后没有出现并发症,患者仍在接受 10 个月的随访。由于有关这种综合征的文献资料有限,而且儿童舌骨乳头状瘤经常出现,因此牙科医生需要熟悉这种疾病。
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引用次数: 0
Longitudinal association between oral function and underweight onset among community-dwelling older adults: Role of regular self-weighing. 社区老年人口腔功能与体重不足发病之间的纵向联系:定期自我称重的作用
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-01-08 DOI: 10.1111/scd.12954
Yuta Kubo, Keisuke Fujii, Taiji Noguchi, Takahiro Hayashi, Naoki Tomiyama, Akira Ochi, Hiroyuki Hayashi

Aims: Regular self-weighing is effective in weight management and may help to mitigate the risk of underweight among older adults. We examined which factors of oral function are associated with a risk for underweight among community-dwelling older adults and whether regular self-weighing can mitigate that risk.

Methods: This was a cohort study. Self-administered questionnaires were mailed to 7665 older adults in March 2019 (response rate 74.3%) and 7591 in March 2020 (response rate 74.7%). Among those who responded to both surveys, 3594 older adults who were not underweight in March 2019 were included (follow-up rate: 59.2%). We examined the association between dysphagia, poor masticatory function, and dry mouth and the development of underweight, and whether regular self-weighing reduced the risk for underweight.

Results: The average age ± standard deviation of participants was 71.1 ± 3.4 years. There was a significant association between swallowing difficulty and the occurrence of underweight (odds ratio = 1.65, p = .012). However, this relationship did not differ significantly with regular self-weighing (p = .477).

Conclusions: These study findings suggest that to prevent underweight among community-dwelling older adults, it is important to focus on those with poor swallowing function.

目的:定期自我称体重可有效控制体重,有助于减轻老年人体重不足的风险。我们研究了哪些口腔功能因素与居住在社区的老年人体重不足的风险有关,以及定期自我称体重是否能减轻这种风险:这是一项队列研究。分别于 2019 年 3 月和 2020 年 3 月向 7665 名老年人(回复率为 74.3%)和 7591 名老年人(回复率为 74.7%)邮寄了自填式问卷。在这两次调查的回复者中,有 3594 名在 2019 年 3 月体重没有过轻的老年人被纳入调查(随访率:59.2%)。我们研究了吞咽困难、咀嚼功能差、口干与体重不足之间的关系,以及定期自我称重是否会降低体重不足的风险:参与者的平均年龄(标准差)为 71.1 ± 3.4 岁。吞咽困难与体重不足之间存在明显的关联(几率比=1.65,P=0.012)。然而,这种关系与定期自我称重并无显著差异(p = .477):这些研究结果表明,要防止社区老年人体重不足,必须重点关注吞咽功能差的老年人。
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引用次数: 0
Ulectomy in a patient with nephrotic syndrome under investigation for Galloway-Mowat syndrome: a case report. 一名肾病综合征患者在接受加洛韦-莫瓦特综合征检查时进行了尿道切除术:病例报告。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-02-06 DOI: 10.1111/scd.12971
Gabriela Reis Alves, Julia Biliato Javaroni, Ana Paula Gomes E Moura, Alberto Consolaro, Raquel Assed Bezerra Segato

The aim of this study is to report a case in which a patient with nephrotic syndrome underwent surgery to remove fibrous gum tissue (ulectomy). An 8-year-old patient, diagnosed with early onset nephrotic syndrome due to a mutation in the NUP107 gene, had received a kidney transplant and was therefore taking various medications, including immunosuppressants. On oral examination, the patient was found to have a fibrous gingiva that was preventing the eruption of the upper permanent central incisors. A ulectomy was performed and the gingival tissue was sent for histopathological analysis, which showed normal aspects. The upper right central incisor was seen in the oral cavity 15 days after surgery. A second procedure was carried out to facilitate the eruption of the upper left incisor, which was visualized in the oral cavity 30 days later. In addition, oral manifestations such as maxillary atresia, ogival palate and mouth breathing were observed. Therefore, the role of the dental surgeon in the lives of transplanted children is considered important, as they often take various medications that can affect their oral health. Thus, early diagnosis and effective treatment will be essential to prevent future malocclusions and thus improve the quality of life of these patients.

本研究旨在报告一例肾病综合征患者接受手术切除纤维牙龈组织(尿道切除术)的病例。一名 8 岁的患者因 NUP107 基因突变被诊断为早发性肾病综合征,曾接受过肾移植手术,因此正在服用包括免疫抑制剂在内的各种药物。口腔检查发现,患者的牙龈纤维化,阻碍了上恒中切牙的萌出。患者接受了牙槽骨切除术,牙龈组织被送去进行组织病理学分析,结果显示一切正常。术后 15 天,在口腔中看到了右上中切牙。为了促进左上切牙的萌出,进行了第二次手术,30 天后在口腔中看到了这颗切牙。此外,还观察到上颌闭锁、腭咽畸形和口呼吸等口腔表现。因此,牙科医生在移植儿童的生活中扮演着重要的角色,因为他们经常服用各种药物,这些药物可能会影响他们的口腔健康。因此,早期诊断和有效治疗对于预防未来的畸形从而改善这些患者的生活质量至关重要。
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引用次数: 0
The oral health-related quality of life of children with fetal alcohol spectrum disorder. 胎儿酒精谱系障碍儿童与口腔健康相关的生活质量。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-03-12 DOI: 10.1111/scd.12993
Mohammad Saad Khawer, Keith Da Silva

Introduction: A child's oral health impacts their development and quality of life. Children who live with fetal alcohol spectrum disorder (FASD) face barriers to dental care combined with poorer oral health outcomes. However, how this affects their oral health-related quality of life (OHRQoL) is largely unknown. Thus, the aim of this study is to examine the OHRQoL of children living with FASD.

Methods: This cross-sectional survey used the Child Oral Health Impact Profile-Short Form-19 (COHIP-SF-19) to evaluate the OHRQoL quality of life of children (aged 8 to 15) living with FASD, compared to healthy controls.

Results: A total of 332 children (or their caregivers) completed the survey. The survey results showed that children living with FASD reported significantly more untreated dental conditions. The majority of children in the control group experienced a low impact across the majority of COHIP-SF-19 domains. However, children living with FASD experienced significantly higher impact scores related to oral health, functional well-being, and social-emotional well-being.

Conclusion: The results demonstrated that children who live with FASD have a poorer OHRQoL. Overall, more investigation is necessary to identify the best ways to improve the OHRQoL of children living with FASD.

引言儿童的口腔健康影响着他们的发育和生活质量。患有胎儿酒精中毒谱系障碍(FASD)的儿童面临着牙科保健的障碍和较差的口腔健康结果。然而,这对他们与口腔健康相关的生活质量(OHRQoL)有何影响在很大程度上还不得而知。因此,本研究旨在调查 FASD 儿童的口腔健康相关生活质量:这项横断面调查使用儿童口腔健康影响档案-短表-19(COHIP-SF-19)来评估患有 FASD 的儿童(8 至 15 岁)与健康对照组相比的 OHRQoL 生活质量:共有 332 名儿童(或其照顾者)完成了调查。调查结果显示,患有 FASD 的儿童报告的未经治疗的牙科疾病明显增多。对照组中的大多数儿童在 COHIP-SF-19 的大多数领域中受到的影响较小。然而,患有 FASD 的儿童在口腔健康、功能幸福感和社会情感幸福感方面的影响得分明显更高:结论:研究结果表明,患有 FASD 的儿童的 OHRQoL 较差。总体而言,有必要开展更多调查,以确定改善 FASD 儿童 OHRQoL 的最佳方法。
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引用次数: 0
Patient communication protocols for sexually transmitted infections: A systematic review. 性传播感染的患者沟通协议:系统综述。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-02-20 DOI: 10.1111/scd.12976
Laura Borges Kirschnick, Camila Barcellos Calderipe, Alessandro Villa, Erison Santana Dos Santos, Cesar Migliorati, Manoela Domingues Martins, Alan Roger Santos-Silva

Aims: We conducted a systematic review of post-test communication protocols and observational studies regarding counseling for a positive sexually transmitted infection (STI) result and also discuss the role of dental specialist (e.g., oral medicine) in this sense.

Methods and results: The search process followed the parameters of PRISMA 2020 guidelines. MEDLINE/PubMed, Web of Science, Scopus, EMBASE, and LILACS were consulted with a specific search strategy for each one. Additionally, the references of the included studies, grey literature, and experts were consulted. Four protocols and 18 observational studies were included in this systematic review, published between 1997 and 2022 in the Americas and Europe. The communication protocols emphasized the importance of conducting personal and private discussions with patients to address their fears and questions. Among the observational studies, 56% indicated that post-test counseling was either ineffective or absent. Furthermore, 22% of the studies used telephone communication to deliver results to patients.

Conclusions: Our study showed that the communication process of a positive STI result affects the patients in several aspects, as treatment adherence and their relationship with the community. Nevertheless, this process of STI post-test communication seems to be flawed, which brings potential negative effects to patients.

目的:我们对有关性传播感染(STI)阳性结果咨询的检测后沟通协议和观察性研究进行了系统性综述,并讨论了牙科专家(如口腔医学专家)在此方面的作用:搜索过程遵循 PRISMA 2020 指南的参数。参考了 MEDLINE/PubMed、Web of Science、Scopus、EMBASE 和 LILACS,并为每种检索制定了特定的检索策略。此外,还参考了纳入研究的参考文献、灰色文献和专家意见。本系统综述共纳入了 1997 年至 2022 年间在美洲和欧洲发表的 4 份协议和 18 项观察性研究。沟通协议强调了与患者进行个人私下讨论以消除他们的恐惧和疑问的重要性。在观察性研究中,56% 的研究表明,检测后咨询要么无效,要么不存在。此外,22%的研究采用电话沟通的方式将结果告知患者:我们的研究表明,性传播感染阳性结果的沟通过程会在多个方面影响患者,如坚持治疗以及他们与社区的关系。然而,性传播感染检测后的沟通过程似乎存在缺陷,给患者带来了潜在的负面影响。
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引用次数: 0
Digital nasoalveolar molding through presurgical orthopedics in newborns/infants with cleft lip and palate: A comprehensive review and case study. 通过唇腭裂新生儿/婴儿术前矫形进行数字化鼻齿槽成型:全面回顾与病例研究。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-03-11 DOI: 10.1111/scd.12989
Katia Villarreal-Martínez, Victor Fierro-Serna, Miguel A Rosales-Berber, Vanessa Alejandri-Gamboa, Gabriela Torre-Delgadillo, Socorro Ruiz-Rodríguez, Amaury Pozos-Guillén, Arturo Garrocho-Rangel

Aims: This study aims to provide a comprehensive review and case study about the advantages and disadvantages of the application of digital technologies in presurgical orthopedics in newborns/infants with cleft lip and palate (CLCP). Positive changes in the nasal anatomy, maxillary arch, and cleft width could be achieved.

Methods: Three representative cases of newborns/infants with CLCP were managed using the presurgical newborn/infant orthopedics (PSIO) approach. The patients were diagnosed and treated. Detailed descriptions of the impression procedures and PSIO appliance construction and placement were provided for each case.

Results: Case 1 utilized traditional impression techniques, Case 2 employed a semi-digitalized approach with intraoral digital scanning, and Case 3 utilized a completely digitalized method for appliance construction. Positive changes in maxillary arch dimensions and cleft width reduction were observed in all cases.

Conclusions: The management of CLCP in newborns and infants poses a complex challenge with profound implications. The PSIO approach not only facilitates reconstructive surgery but also enhances overall quality of life. Digital tools, like specialized optical scanners and 3D printing, revolutionize the PSIO process, making it more efficient and patient-friendly. Clinical benefits include improved facial morphology, esthetics, feeding, speech, and optimized future surgical results. Despite ongoing efficacy debates, global adoption as the initial surgical approach underscores its value. The integration of digital technologies offers new hope for patients and families, promising a brighter future for those affected by this congenital condition.

目的:本研究旨在对数字技术在唇腭裂新生儿/婴儿术前矫形中的应用利弊进行全面回顾和案例研究。方法:方法:采用术前新生儿/婴儿矫形(PSIO)方法对三例具有代表性的新生儿/婴儿唇腭裂患者进行了治疗。对患者进行了诊断和治疗。结果:结果:病例 1 采用了传统的印模技术,病例 2 采用了口内数字扫描的半数字化方法,而病例 3 则采用了完全数字化的矫治器制作方法。所有病例的上颌牙弓尺寸和裂隙宽度都有积极的变化:新生儿和婴儿 CLCP 的治疗是一项复杂的挑战,影响深远。PSIO 方法不仅有利于重建手术,还能提高整体生活质量。专用光学扫描仪和三维打印等数字化工具彻底改变了 PSIO 流程,使其更高效、更方便患者。临床效果包括改善面部形态、美观、进食、语言能力,以及优化未来的手术效果。尽管对其疗效的争论仍在继续,但作为最初的手术方法在全球范围内的采用凸显了其价值。数字技术的整合为患者和家属带来了新的希望,有望为先天性疾病患者带来更光明的未来。
{"title":"Digital nasoalveolar molding through presurgical orthopedics in newborns/infants with cleft lip and palate: A comprehensive review and case study.","authors":"Katia Villarreal-Martínez, Victor Fierro-Serna, Miguel A Rosales-Berber, Vanessa Alejandri-Gamboa, Gabriela Torre-Delgadillo, Socorro Ruiz-Rodríguez, Amaury Pozos-Guillén, Arturo Garrocho-Rangel","doi":"10.1111/scd.12989","DOIUrl":"10.1111/scd.12989","url":null,"abstract":"<p><strong>Aims: </strong>This study aims to provide a comprehensive review and case study about the advantages and disadvantages of the application of digital technologies in presurgical orthopedics in newborns/infants with cleft lip and palate (CLCP). Positive changes in the nasal anatomy, maxillary arch, and cleft width could be achieved.</p><p><strong>Methods: </strong>Three representative cases of newborns/infants with CLCP were managed using the presurgical newborn/infant orthopedics (PSIO) approach. The patients were diagnosed and treated. Detailed descriptions of the impression procedures and PSIO appliance construction and placement were provided for each case.</p><p><strong>Results: </strong>Case 1 utilized traditional impression techniques, Case 2 employed a semi-digitalized approach with intraoral digital scanning, and Case 3 utilized a completely digitalized method for appliance construction. Positive changes in maxillary arch dimensions and cleft width reduction were observed in all cases.</p><p><strong>Conclusions: </strong>The management of CLCP in newborns and infants poses a complex challenge with profound implications. The PSIO approach not only facilitates reconstructive surgery but also enhances overall quality of life. Digital tools, like specialized optical scanners and 3D printing, revolutionize the PSIO process, making it more efficient and patient-friendly. Clinical benefits include improved facial morphology, esthetics, feeding, speech, and optimized future surgical results. Despite ongoing efficacy debates, global adoption as the initial surgical approach underscores its value. The integration of digital technologies offers new hope for patients and families, promising a brighter future for those affected by this congenital condition.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140102629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Symmetrical lipomatosis of the tongue: A comprehensive case report offering clinical and histopathological perspectives. 对称性舌脂肪瘤病:提供临床和组织病理学视角的综合病例报告。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-02-04 DOI: 10.1111/scd.12970
Vithor Zago Esteves, Jorge Esquiche León, Andreia Bufalino
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引用次数: 0
Oral candida lesions and Candida tropicalis: Potential prognostic markers in end-of-life cancer patients. 口腔念珠菌病变和热带念珠菌:临终癌症患者的潜在预后标志。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-01-02 DOI: 10.1111/scd.12955
Maiko Shimosato, Shinpei Kada, Eriko Yase, Naoki Sakane

Aims: Oral candidosis is common in patients with end-of-life cancer; however, its prognosis is unclear. We aimed to assess oral candidosis and Candida species as prognostic indicators in palliative care for these patients.

Methods: We consecutively included palliative care patients, assessed for candidosis via microbiological techniques, and classified into three groups by the extent of oral lesions. The association between oral candidosis and overall survival was assessed using a Cox proportional hazards model adjusted by performance status (PS).

Results: We studied 142 patients (median age 77; 52.8% women) with a 76.1% oral candidosis prevalence. Candida albicans (80.6%) was the most common species. Oral lesions were classified as none, grade 1 (28.7%), or ≥ grade 2 (14.8%). During follow-up, Cox models identified ≥grade 2 lesions (aHR = 2.04; 95% CI: 1.18-3.54; p = .011) and Candida tropicalis (aHR = 2.38; 95% CI: 1.03-5.55; p = .044) as predictors.

Conclusion: The extent of oral candidosis lesions or the presence of C. tropicalis may serve as prognostic indicator in patients with end-of-life cancer. Therefore, solely concentrating on the prevalence and frequency of fungal species may be insufficient for predicting life prognosis; it is advisable to assess these parameters through both visual examination and culture.

目的:口腔念珠菌病在临终癌症患者中很常见,但其预后尚不明确。我们的目的是评估口腔念珠菌病和念珠菌种类作为这些患者姑息治疗的预后指标:我们连续纳入了姑息治疗患者,通过微生物学技术评估了念珠菌病,并根据口腔病变程度分为三组。结果:我们研究了 142 名患者(中位数)的口腔念珠菌病和总生存期之间的关系:我们研究了 142 名患者(中位年龄 77 岁;52.8% 为女性),其口腔念珠菌病发病率为 76.1%。白色念珠菌(80.6%)是最常见的菌种。口腔病变分为无、1级(28.7%)或≥2级(14.8%)。在随访期间,Cox 模型发现≥2 级病变(aHR = 2.04;95% CI:1.18-3.54;p = .011)和热带念珠菌(aHR = 2.38;95% CI:1.03-5.55;p = .044)是预测因素:结论:口腔念珠菌病变的程度或热带念珠菌的存在可作为临终癌症患者的预后指标。结论:口腔念珠菌病病变的程度或热带念珠菌的存在可作为临终癌症患者的预后指标,因此,仅关注真菌种类的流行率和频率可能不足以预测预后;建议通过肉眼检查和培养来评估这些参数。
{"title":"Oral candida lesions and Candida tropicalis: Potential prognostic markers in end-of-life cancer patients.","authors":"Maiko Shimosato, Shinpei Kada, Eriko Yase, Naoki Sakane","doi":"10.1111/scd.12955","DOIUrl":"10.1111/scd.12955","url":null,"abstract":"<p><strong>Aims: </strong>Oral candidosis is common in patients with end-of-life cancer; however, its prognosis is unclear. We aimed to assess oral candidosis and Candida species as prognostic indicators in palliative care for these patients.</p><p><strong>Methods: </strong>We consecutively included palliative care patients, assessed for candidosis via microbiological techniques, and classified into three groups by the extent of oral lesions. The association between oral candidosis and overall survival was assessed using a Cox proportional hazards model adjusted by performance status (PS).</p><p><strong>Results: </strong>We studied 142 patients (median age 77; 52.8% women) with a 76.1% oral candidosis prevalence. Candida albicans (80.6%) was the most common species. Oral lesions were classified as none, grade 1 (28.7%), or ≥ grade 2 (14.8%). During follow-up, Cox models identified ≥grade 2 lesions (aHR = 2.04; 95% CI: 1.18-3.54; p = .011) and Candida tropicalis (aHR = 2.38; 95% CI: 1.03-5.55; p = .044) as predictors.</p><p><strong>Conclusion: </strong>The extent of oral candidosis lesions or the presence of C. tropicalis may serve as prognostic indicator in patients with end-of-life cancer. Therefore, solely concentrating on the prevalence and frequency of fungal species may be insufficient for predicting life prognosis; it is advisable to assess these parameters through both visual examination and culture.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139089050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mucocutaneous histoplasmosis as the first manifestation of AIDS. 粘膜组织胞浆菌病是艾滋病的首发症状。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-02-06 DOI: 10.1111/scd.12972
Janaina B Medina, Francèle Monguilhott-Falbo, Cristiane Teixeira-Leite, Marilia Trierveiler, Paulo Henrique Braz-Silva, Karem L Ortega

Immunosuppressed patients can present with opportunistic infections resulting from an intrinsic systemic disease, which easily evolves into more aggressive and less common conditions. This work reports a clinical case of a female patient with histoplasmosis lesions in the nasal and oral mucosa, including pulmonary, hematological, and hepatic impairment, which led to the diagnosis of HIV seropositivity. In the presence of severe immunosuppression, morbidity is increased due to deep fungal infections and their unusual clinical characteristics can make diagnosis difficult. Therefore, it can be very helpful to recognize these clinical characteristics in order to determine early diagnostic interventions. It is important to recognize mucocutaneous manifestations of histoplasmosis because the biopsy of these lesions, and subsequent histopathological analysis, is one of the quickest, safest, and cheapest methods of diagnosis.

免疫抑制患者可能会因内在的系统性疾病而出现机会性感染,这种感染很容易演变成更具侵袭性和更少见的病症。本研究报告了一例女性患者的临床病例,该患者的鼻腔和口腔粘膜出现组织胞浆菌病病变,包括肺部、血液学和肝脏功能受损,最终被诊断为艾滋病毒血清阳性。在存在严重免疫抑制的情况下,深部真菌感染的发病率会增加,而且其不寻常的临床特征会给诊断带来困难。因此,识别这些临床特征对确定早期诊断干预措施很有帮助。识别组织胞浆菌病的粘膜表现非常重要,因为对这些病变进行活检和随后的组织病理学分析是最快速、安全和廉价的诊断方法之一。
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引用次数: 0
The evaluation of clinical factors affecting oral health impacts on the quality of life of Iranian elderly patients visiting dental clinics: A cross-sectional study. 评估影响口腔健康的临床因素对就诊于牙科诊所的伊朗老年患者生活质量的影响:一项横断面研究。
IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-01 Epub Date: 2024-03-02 DOI: 10.1111/scd.12980
Nazanin Mirhosseini, Reyhaneh Shoorgashti, Simin Lesan

Background: Iran will soon have an aging population. Healthcare providers must consider factors affecting the quality of life for those 60 and older. Understanding oral health as one of these factors can improve the elderly's quality of life. Oral health-related quality of life (OHRQoL) is a crucial reflection of individuals' general well-being and their overall quality of life linked to health. This study aimed to evaluate the OHRQoL among elderly Iranians referring to Azad University of Medical Sciences in Tehran.

Methods: In this cross-sectional study, 171 individuals over 65 (93 men and 78 women) were evaluated using OHIP-14 and GOHAI-12 questionnaires to analyze their quality of life. Gender, age, systemic diseases, using medications and dentures, the number of remaining teeth, and oral lesions were recorded. Salivary flow and xerostomia were analyzed with the spitting method and xerostomia index questionnaire, respectively. Also, four main flavor solutions were used to evaluate the taste perception. Data were analyzed using PASS11 and p value < .05 was the significance level.

Results: Based on OHIP-14 and GOHAI-12, Iranian older people's quality of life can be affected by cardiovascular diseases, hypertension, xerostomia, and the number of remaining teeth (p < .05). The results also showed a significant correlation between the OHIP-14 and GOHAI-12 scores (p < .001). Both indexes revealed that the number of remaining teeth, xerostomia, salivary flow, and taste perception greatly influenced participants' quality of life. More remaining teeth, improved salivary flow, and better perception of sweetness and sourness were all linked to a higher quality of life, while increased xerostomia, reduced salivary flow, and bitter taste perception were linked to a decline in overall well-being. Cardiovascular diseases, hypertension, and medication use were also found to significantly impact quality of life.

Conclusion: This study's results indicate that cardiovascular diseases, hypertension, dry mouth, and tooth loss can negatively impact the elderly's quality of life. So, improving both systemic and oral health is vital for enhancing life quality in this age group.

背景伊朗即将进入人口老龄化社会。医疗服务提供者必须考虑影响 60 岁及以上老年人生活质量的因素。了解口腔健康是这些因素之一,可以提高老年人的生活质量。与口腔健康相关的生活质量(OHRQoL)是个人总体幸福感及其与健康相关的整体生活质量的重要体现。本研究旨在评估在德黑兰阿扎德医科大学就诊的伊朗老年人的口腔健康相关生活质量:在这项横断面研究中,使用 OHIP-14 和 GOHAI-12 问卷对 171 名 65 岁以上的老人(93 名男性和 78 名女性)进行了评估,以分析他们的生活质量。性别、年龄、全身性疾病、使用药物和假牙情况、剩余牙齿数量以及口腔病变情况均被记录在案。唾液流量和口干症分别通过吐唾液法和口干症指数问卷进行分析。此外,还使用了四种主要的味觉溶液来评估味觉感知。使用 PASS11 和 P 值对数据进行分析:根据 OHIP-14 和 GOHAI-12,伊朗老年人的生活质量会受到心血管疾病、高血压、口腔干燥症和剩余牙齿数量的影响(P 结论:本研究结果表明,心血管疾病、高血压、口腔干燥症和剩余牙齿数量会影响老年人的生活质量:本研究结果表明,心血管疾病、高血压、口干和牙齿脱落会对老年人的生活质量产生负面影响。因此,改善全身和口腔健康对提高这一年龄组的生活质量至关重要。
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引用次数: 0
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Special Care in Dentistry
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