{"title":"Supplemental Material for L’impact des symptômes de photosensibilité sur la qualité de vie des personnes atteintes d’un traumatisme craniocérébral modéré à grave : Une étude qualitative","authors":"","doi":"10.1037/cbs0000334.supp","DOIUrl":"https://doi.org/10.1037/cbs0000334.supp","url":null,"abstract":"","PeriodicalId":47733,"journal":{"name":"Canadian Journal of Behavioural Science-Revue Canadienne Des Sciences Du Comportement","volume":"32 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2022-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72908685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Supplemental Material for A Longitudinal Study on the Stability and Predictors of Flourishing Among Emerging Adults","authors":"","doi":"10.1037/cbs0000327.supp","DOIUrl":"https://doi.org/10.1037/cbs0000327.supp","url":null,"abstract":"","PeriodicalId":47733,"journal":{"name":"Canadian Journal of Behavioural Science-Revue Canadienne Des Sciences Du Comportement","volume":"174 1 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2022-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83647741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Symptômes dépressifs vécus par les parents dans la population générale: État des travaux québécois et canadiens.","authors":"Marie-Ève Clément, Geneviève Piché, A. Villatte","doi":"10.1037/cbs0000298","DOIUrl":"https://doi.org/10.1037/cbs0000298","url":null,"abstract":"","PeriodicalId":47733,"journal":{"name":"Canadian Journal of Behavioural Science-Revue Canadienne Des Sciences Du Comportement","volume":"20 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78876644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exceptional Canadian contributions to research on cognitive vulnerability to depression.","authors":"David J. A. Dozois, E. Hayden","doi":"10.1037/cbs0000301","DOIUrl":"https://doi.org/10.1037/cbs0000301","url":null,"abstract":"","PeriodicalId":47733,"journal":{"name":"Canadian Journal of Behavioural Science-Revue Canadienne Des Sciences Du Comportement","volume":"1 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77073734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-01Epub Date: 2022-03-12DOI: 10.1016/j.jbc.2022.101829
Caroline E Dewar, Silke Oeljeklaus, Christoph Wenger, Bettina Warscheid, André Schneider
The mitochondrial F1Fo ATP synthase of the parasite Trypanosoma brucei has been previously studied in detail. This unusual enzyme switches direction in functionality during the life cycle of the parasite, acting as an ATP synthase in the insect stages, and as an ATPase to generate mitochondrial membrane potential in the mammalian bloodstream stages. Whereas the trypanosome F1 moiety is relatively highly conserved in structure and composition, the Fo subcomplex and the peripheral stalk have been shown to be more variable. Interestingly, a core subunit of the latter, the normally conserved subunit b, has been resistant to identification by sequence alignment or biochemical methods. Here, we identified a 17 kDa mitochondrial protein of the inner membrane, Tb927.8.3070, that is essential for normal growth, efficient oxidative phosphorylation, and membrane potential maintenance. Pull-down experiments and native PAGE analysis indicated that the protein is both associated with the F1Fo ATP synthase and integral to its assembly. In addition, its knockdown reduced the levels of Fo subunits, but not those of F1, and disturbed the cell cycle. Finally, analysis of structural homology using the HHpred algorithm showed that this protein has structural similarities to Fo subunit b of other species, indicating that this subunit may be a highly diverged form of the elusive subunit b.
以前曾对布氏锥虫线粒体 F1Fo ATP 合成酶进行过详细研究。这种不寻常的酶在寄生虫的生命周期中转换了功能方向，在昆虫阶段作为 ATP 合成酶，而在哺乳动物的血流阶段作为 ATP 酶产生线粒体膜电位。虽然锥虫 F1 分子的结构和组成相对高度保守，但 Fo 亚复合体和外围柄的结构和组成却比较多变。有趣的是，后者的一个核心亚基，即通常保守的 b 亚基，一直无法通过序列比对或生化方法进行鉴定。在这里，我们发现了一种 17 kDa 的线粒体内膜蛋白质 Tb927.8.3070，它对正常生长、高效氧化磷酸化和膜电位维持至关重要。牵引实验和原生 PAGE 分析表明，该蛋白既与 F1Fo ATP 合酶相关，又是其组装不可或缺的部分。此外，它的敲除降低了 Fo 亚基的水平，但没有降低 F1 亚基的水平，并扰乱了细胞周期。最后，使用 HHpred 算法进行的结构同源性分析表明，该蛋白与其他物种的 Fo 亚基 b 具有结构相似性，表明该亚基可能是难以捉摸的亚基 b 的高度分化形式。
{"title":"Characterization of a highly diverged mitochondrial ATP synthase F<sub>o</sub> subunit in Trypanosoma brucei.","authors":"Caroline E Dewar, Silke Oeljeklaus, Christoph Wenger, Bettina Warscheid, André Schneider","doi":"10.1016/j.jbc.2022.101829","DOIUrl":"10.1016/j.jbc.2022.101829","url":null,"abstract":"<p><p>The mitochondrial F<sub>1</sub>F<sub>o</sub> ATP synthase of the parasite Trypanosoma brucei has been previously studied in detail. This unusual enzyme switches direction in functionality during the life cycle of the parasite, acting as an ATP synthase in the insect stages, and as an ATPase to generate mitochondrial membrane potential in the mammalian bloodstream stages. Whereas the trypanosome F<sub>1</sub> moiety is relatively highly conserved in structure and composition, the F<sub>o</sub> subcomplex and the peripheral stalk have been shown to be more variable. Interestingly, a core subunit of the latter, the normally conserved subunit b, has been resistant to identification by sequence alignment or biochemical methods. Here, we identified a 17 kDa mitochondrial protein of the inner membrane, Tb927.8.3070, that is essential for normal growth, efficient oxidative phosphorylation, and membrane potential maintenance. Pull-down experiments and native PAGE analysis indicated that the protein is both associated with the F<sub>1</sub>F<sub>o</sub> ATP synthase and integral to its assembly. In addition, its knockdown reduced the levels of F<sub>o</sub> subunits, but not those of F<sub>1</sub>, and disturbed the cell cycle. Finally, analysis of structural homology using the HHpred algorithm showed that this protein has structural similarities to F<sub>o</sub> subunit b of other species, indicating that this subunit may be a highly diverged form of the elusive subunit b.</p>","PeriodicalId":47733,"journal":{"name":"Canadian Journal of Behavioural Science-Revue Canadienne Des Sciences Du Comportement","volume":"15 1","pages":"101829"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80092407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Major Depressive Disorder is a highly prevalent, recurrent, and debilitating condition, affecting more than 264 million individuals worldwide. Canadian researchers have made significant contributions to the scientific understanding and treatment of depression. For example, Canada ranks first in the world on the number of articles published on depression (and second on papers determined to be Highly Cited in Field) when considering the proportion of researchers in each country. Canadian psychologists have played a critical role in advancing our knowledge of the epidemiology, vulnerability, treatment, and prevention of depression. This special issue presents a series of state-of-the-art empirical reviews that highlight many of the important contributions-covering cognitive vulnerability, perfectionism, epidemiology, cognitive behavioral therapy (CBT), mindfulness, and emotion-focused therapy-that Canadian psychologists have made to our understanding of depression. Some of the key themes from these reviews are summarized in this editorial. Aside from featuring outstanding scholarship, this special issue also serves as a tribute honoring the monumental contributions that many Canadian psychologists have made and as a catalyst to inspire next generation of depression researchers in Canada.Alternate :La dépression majeure (aussi appelée « dépression clinique ») est un trouble très répandu, périodique et débilitant qui touche plus de 264 millions d'individus de par le monde. Les chercheurs et les chercheures du Canada ont grandement contribué aux connaissances scientifiques sur la dépression et sur ses traitements. Par exemple, le Canada est au premier rang dans le monde pour le nombre d'articles publiés sur la dépression (et au deuxième rang parmi les plus cités dans le domaine) lorsqu'on tient compte de la proportion de chercheurs dans chaque pays. Les psychologues canadiens ont joué un rôle déterminant dans l'avancement des connaissances sur l'épidémiologie, la vulnérabilité, le traitement et la prévention de la dépression. Ce numéro spécial présente des revues de haut niveau qui mettent en relief plusieurs des importantes contributions - concernant la vulnérabilité cognitive, le perfectionnisme, l'épidémiologie, la thérapie cognitivo-comportementale (TCC), la pleine conscience, la thérapie centrée sur les émotions - faites par les psychologues canadiens pour améliorer notre compréhension de la dépression. Certains des principaux thèmes de ces revues sont présentés sommairement dans cet éditorial. En plus de mettre en relief certains des chercheurs remarquables, cette livraison spéciale sert aussi d'hommage à plusieurs psychologues canadiens aux contributions monumentales qui ont, en outre, été des sources d'inspiration pour la prochaine génération de chercheurs au pays sur la dépression.
重度抑郁症是一种非常普遍、反复发作和使人衰弱的疾病，影响着全世界超过2.64亿人。加拿大研究人员对抑郁症的科学理解和治疗做出了重大贡献。例如，考虑到每个国家研究人员的比例，加拿大在抑郁症方面发表的文章数量上排名世界第一(在该领域被高度引用的论文数量上排名第二)。加拿大心理学家在提高我们对抑郁症的流行病学、脆弱性、治疗和预防的认识方面发挥了关键作用。本期特刊介绍了一系列最新的实证研究，突出了许多重要的贡献——包括认知脆弱性、完美主义、流行病学、认知行为疗法(CBT)、正念和情感聚焦疗法——加拿大心理学家对我们对抑郁症的理解所做的贡献。本文总结了这些评论中的一些关键主题。除了突出杰出的学术成就外，这期特刊还对许多加拿大心理学家做出的巨大贡献表示敬意，并作为激励加拿大下一代抑郁症研究人员的催化剂。替代方案:不可抗力(aussi appelsamade«danci.com/»)est un trouble truts remacimpandu, danci.com/和danci.com/加上2.64亿d' individual de par le monde。加拿大国立大学和加拿大国立大学联合资助了一项研究:科学研究、研究和研究。例如，“加拿大est au premier rang and le le monde de de de de de articles de publicpublicsamas sur la samacress”(et au deuxi rang parmiles and citcitsdamesanddomaine)或“de de chercheurs dandchaque pays”。心理学家加拿大人不需要旅行或旅行，也不需要旅行或旅行，也不需要旅行或旅行，也不需要旅行或旅行。在这些重要贡献中- -关于脆弱的、完美的、有组织的、有组织的、有良知的、有组织的、有组织的、有组织的、有组织的、有组织的、有组织的、有组织的- - -加拿大人将有组织的、有组织的、有组织的和有组织的。某些基本原则的规定，不包括所有的薪金，也不包括所有的薪金和薪金。此外，在某些情况下，某些人的情绪会得到缓解，例如，在某些情况下，某些人的情绪会得到缓解，例如，在某些情况下，某些人的情绪会得到缓解，例如，在某些情况下，某些人的情绪会得到缓解，例如，某些人的情绪会得到缓解。
{"title":"Introduction to the special issue on exceptional Canadian contributions to research in depression.","authors":"David J. A. Dozois","doi":"10.1037/cbs0000318","DOIUrl":"https://doi.org/10.1037/cbs0000318","url":null,"abstract":"Major Depressive Disorder is a highly prevalent, recurrent, and debilitating condition, affecting more than 264 million individuals worldwide. Canadian researchers have made significant contributions to the scientific understanding and treatment of depression. For example, Canada ranks first in the world on the number of articles published on depression (and second on papers determined to be Highly Cited in Field) when considering the proportion of researchers in each country. Canadian psychologists have played a critical role in advancing our knowledge of the epidemiology, vulnerability, treatment, and prevention of depression. This special issue presents a series of state-of-the-art empirical reviews that highlight many of the important contributions-covering cognitive vulnerability, perfectionism, epidemiology, cognitive behavioral therapy (CBT), mindfulness, and emotion-focused therapy-that Canadian psychologists have made to our understanding of depression. Some of the key themes from these reviews are summarized in this editorial. Aside from featuring outstanding scholarship, this special issue also serves as a tribute honoring the monumental contributions that many Canadian psychologists have made and as a catalyst to inspire next generation of depression researchers in Canada.Alternate :La dépression majeure (aussi appelée « dépression clinique ») est un trouble très répandu, périodique et débilitant qui touche plus de 264 millions d'individus de par le monde. Les chercheurs et les chercheures du Canada ont grandement contribué aux connaissances scientifiques sur la dépression et sur ses traitements. Par exemple, le Canada est au premier rang dans le monde pour le nombre d'articles publiés sur la dépression (et au deuxième rang parmi les plus cités dans le domaine) lorsqu'on tient compte de la proportion de chercheurs dans chaque pays. Les psychologues canadiens ont joué un rôle déterminant dans l'avancement des connaissances sur l'épidémiologie, la vulnérabilité, le traitement et la prévention de la dépression. Ce numéro spécial présente des revues de haut niveau qui mettent en relief plusieurs des importantes contributions - concernant la vulnérabilité cognitive, le perfectionnisme, l'épidémiologie, la thérapie cognitivo-comportementale (TCC), la pleine conscience, la thérapie centrée sur les émotions - faites par les psychologues canadiens pour améliorer notre compréhension de la dépression. Certains des principaux thèmes de ces revues sont présentés sommairement dans cet éditorial. En plus de mettre en relief certains des chercheurs remarquables, cette livraison spéciale sert aussi d'hommage à plusieurs psychologues canadiens aux contributions monumentales qui ont, en outre, été des sources d'inspiration pour la prochaine génération de chercheurs au pays sur la dépression.","PeriodicalId":47733,"journal":{"name":"Canadian Journal of Behavioural Science-Revue Canadienne Des Sciences Du Comportement","volume":"48 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77101815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Hewitt, Martin M. Smith, Sabrina Ge, Marcia Mössler, G. Flett
Perfectionism is a personality style that has been described for decades as highly relevant to depression. Over the past 30 years, our work, as well as the work of other Canadian and international researchers, has attempted to understand the cause and maintenance of perfectionism and the role that this pernicious personality style plays in predisposing individuals to various problems, such as depression. In the present article, we outline our multidimensional and multilevel descriptive model of perfectionism and summarize several models of perfectionism and depression that we have focused on over the years, both from a diathesis–stress perspective and from a more complex developmental and relational perspective. We, then, outline the extant research that we and others have conducted based on these models and conclude by providing a description of and evidence for a dynamic-relational treatment of perfectionism that functions to reduce depressive symptoms and vulnerability to depression. Our article underscores the importance of perfectionism by discussing how it is involved both directly in creating a predisposition to depression and indirectly in precluding accessing, initiating, and benefitting from depression treatment.
{"title":"Perfectionism and its role in depressive disorders.","authors":"P. Hewitt, Martin M. Smith, Sabrina Ge, Marcia Mössler, G. Flett","doi":"10.1037/cbs0000306","DOIUrl":"https://doi.org/10.1037/cbs0000306","url":null,"abstract":"Perfectionism is a personality style that has been described for decades as highly relevant to depression. Over the past 30 years, our work, as well as the work of other Canadian and international researchers, has attempted to understand the cause and maintenance of perfectionism and the role that this pernicious personality style plays in predisposing individuals to various problems, such as depression. In the present article, we outline our multidimensional and multilevel descriptive model of perfectionism and summarize several models of perfectionism and depression that we have focused on over the years, both from a diathesis–stress perspective and from a more complex developmental and relational perspective. We, then, outline the extant research that we and others have conducted based on these models and conclude by providing a description of and evidence for a dynamic-relational treatment of perfectionism that functions to reduce depressive symptoms and vulnerability to depression. Our article underscores the importance of perfectionism by discussing how it is involved both directly in creating a predisposition to depression and indirectly in precluding accessing, initiating, and benefitting from depression treatment.","PeriodicalId":47733,"journal":{"name":"Canadian Journal of Behavioural Science-Revue Canadienne Des Sciences Du Comportement","volume":"1 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89130857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emotion-focused therapy for depression: Canadian contributions.","authors":"L. Greenberg, J. Watson","doi":"10.1037/cbs0000317","DOIUrl":"https://doi.org/10.1037/cbs0000317","url":null,"abstract":"","PeriodicalId":47733,"journal":{"name":"Canadian Journal of Behavioural Science-Revue Canadienne Des Sciences Du Comportement","volume":"23 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73454020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Canadian contributions to cognitive behavioral therapy for depression.","authors":"L. Quilty, Leanne Quigley, K. Dobson","doi":"10.1037/cbs0000293","DOIUrl":"https://doi.org/10.1037/cbs0000293","url":null,"abstract":"","PeriodicalId":47733,"journal":{"name":"Canadian Journal of Behavioural Science-Revue Canadienne Des Sciences Du Comportement","volume":"154 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83788914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mindfulness meditation in the long-term management of mood disorders: Contributions by Canadian researchers.","authors":"Amanda L. Shamblaw, Z. Segal","doi":"10.1037/cbs0000286","DOIUrl":"https://doi.org/10.1037/cbs0000286","url":null,"abstract":"","PeriodicalId":47733,"journal":{"name":"Canadian Journal of Behavioural Science-Revue Canadienne Des Sciences Du Comportement","volume":"11 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79708659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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