Paraquat (PQ) herbicide poisoning is a severe medical problem in developing countries without suitable therapy. This study aimed to investigate the effects of crocin (CCN) and nano crocin (NCCN) on PQ -induced toxicity in the MRC-5 cell line. The results showed that the particle size of NCCN was 140.3 ± 18.0 nm, and the zeta potential of the optimal crocin-loaded niosomes was 23.4 ± 2.8 mV. The NCCN was more effective than CCN in the inhibition of PQ-induced toxicity. Treatment of the MRC-5 cells leads to a decrease in ROS and an increase in SOD, CAT, GPX, and TAC levels in PQ-CCN and PQ-NCCN groups compared with the PQ group. These changes tended to be positively associated with the NCCN compared to CCN. Overall, NCCN was more effective than crocin in treating PQ-induced toxicity in vitro and deserved further preclinical consideration.
{"title":"Nanocrocin Protective Effects on Paraquat-Induced Oxidative Stress in the MRC-5 Cell Line.","authors":"Akram Oftadeh Harsin, Farzin Firozian, Amir Nili Ahmadabadi, Meysam Soleimani, Akram Ranjbar","doi":"10.1007/s12291-022-01096-y","DOIUrl":"10.1007/s12291-022-01096-y","url":null,"abstract":"<p><p>Paraquat (PQ) herbicide poisoning is a severe medical problem in developing countries without suitable therapy. This study aimed to investigate the effects of crocin (CCN) and nano crocin (NCCN) on PQ -induced toxicity in the MRC-5 cell line. The results showed that the particle size of NCCN was 140.3 ± 18.0 nm, and the zeta potential of the optimal crocin-loaded niosomes was 23.4 ± 2.8 mV. The NCCN was more effective than CCN in the inhibition of PQ-induced toxicity. Treatment of the MRC-5 cells leads to a decrease in ROS and an increase in SOD, CAT, GPX, and TAC levels in PQ-CCN and PQ-NCCN groups compared with the PQ group. These changes tended to be positively associated with the NCCN compared to CCN. Overall, NCCN was more effective than crocin in treating PQ-induced toxicity in vitro and deserved further preclinical consideration.</p>","PeriodicalId":47734,"journal":{"name":"Climate and Development","volume":"14 1","pages":"283-290"},"PeriodicalIF":2.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10987410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79182150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-05DOI: 10.1080/17565529.2023.2298805
Linn Burchert
{"title":"Concealing, naming, or tackling inequalities? Art, culture and (In)justice at COP27","authors":"Linn Burchert","doi":"10.1080/17565529.2023.2298805","DOIUrl":"https://doi.org/10.1080/17565529.2023.2298805","url":null,"abstract":"","PeriodicalId":47734,"journal":{"name":"Climate and Development","volume":"25 14","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139383746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-22DOI: 10.1080/17565529.2023.2264259
Mukul Kumar
{"title":"Violent transitions: towards a political ecology of coal and hydropower in India","authors":"Mukul Kumar","doi":"10.1080/17565529.2023.2264259","DOIUrl":"https://doi.org/10.1080/17565529.2023.2264259","url":null,"abstract":"","PeriodicalId":47734,"journal":{"name":"Climate and Development","volume":"15 10","pages":""},"PeriodicalIF":4.3,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138944725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-13DOI: 10.1080/17565529.2023.2289533
Douwe van Schie, K. McNamara, Merewalesi Yee, A. Mirza, Ross Westoby, M. M. Nand, Rawnak Jahan Khan Ranon, R. Clissold, Simon Anderson, S. Huq
{"title":"Valuing a values-based approach for assessing loss and damage","authors":"Douwe van Schie, K. McNamara, Merewalesi Yee, A. Mirza, Ross Westoby, M. M. Nand, Rawnak Jahan Khan Ranon, R. Clissold, Simon Anderson, S. Huq","doi":"10.1080/17565529.2023.2289533","DOIUrl":"https://doi.org/10.1080/17565529.2023.2289533","url":null,"abstract":"","PeriodicalId":47734,"journal":{"name":"Climate and Development","volume":"32 3","pages":""},"PeriodicalIF":4.3,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138976461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-13DOI: 10.1080/17565529.2023.2282486
Itishree Pattnaik, Kuntala Lahiri-Dutt
{"title":"Feminization of hunger in climate change: linking rural women’s health and wellbeing in India","authors":"Itishree Pattnaik, Kuntala Lahiri-Dutt","doi":"10.1080/17565529.2023.2282486","DOIUrl":"https://doi.org/10.1080/17565529.2023.2282486","url":null,"abstract":"","PeriodicalId":47734,"journal":{"name":"Climate and Development","volume":"132 37","pages":""},"PeriodicalIF":4.3,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139004320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-10DOI: 10.1080/17565529.2023.2287744
George Dakurah, Prince Osei-Wusu Adjei, Henny Osbahr
{"title":"We used to ‘chase the rains’ away in the past: the role of cultural values and beliefs in shaping farmers’ perceptions of climate variability and change in North-west Ghana","authors":"George Dakurah, Prince Osei-Wusu Adjei, Henny Osbahr","doi":"10.1080/17565529.2023.2287744","DOIUrl":"https://doi.org/10.1080/17565529.2023.2287744","url":null,"abstract":"","PeriodicalId":47734,"journal":{"name":"Climate and Development","volume":"178 ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138982480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.1080/17565529.2023.2282482
Richard Grant, S. S. Roy, Camilla Jimenez Zablah, Perla Aquino, Madisyn Simpson, Paula Viala
{"title":"Climate adaptation and resilience indices for the Caribbean region: an assessment of four leading indices","authors":"Richard Grant, S. S. Roy, Camilla Jimenez Zablah, Perla Aquino, Madisyn Simpson, Paula Viala","doi":"10.1080/17565529.2023.2282482","DOIUrl":"https://doi.org/10.1080/17565529.2023.2282482","url":null,"abstract":"","PeriodicalId":47734,"journal":{"name":"Climate and Development","volume":"27 12","pages":""},"PeriodicalIF":4.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138627192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-14DOI: 10.1080/17565529.2023.2266420
Yang Li, Yuxuan Liang, Jianchi Tian, Yan Sun, Meijun Meng
ABSTRACTConsidering the dual objectives of financial climate policies (such as carbon tax) -mitigating climate change and supporting economic growth, our paper aims to discover the unique process of increasing support for financial climate policies, which was a lack of attention before. Building on the structural equation modelling analysis of a nationwide longitudinal survey including 2322 valid samples in China, this research finds the positive influence of climate anxiety and economic anticipation on the support for financial climate policies, driven by the enhancement of perceived win-win benefits of policies. The findings provide researchers with a new perspective in understanding public support for financial climate policies and the psychological process underneath. Policy-makers could benefit from the findings by strategically managing the climate anxiety and economic anticipation of the public and raising public awareness of personal benefits beyond climate benefits when implementing financial climate policies.KEYWORDS: Climate changefinancial climate policiesclimate anxietyeconomic anticipationperceived benefit Disclosure statementNo potential conflict of interest was reported by the author(s).Additional informationFundingThis work was supported by the National Natural Science Foundation of China [grant number 71902005].Notes on contributorsYang LiYang Li is an associate professor of Marketing at Beijing Technology and Business University.Yuxuan LiangYuxuan Liang is a postgraduate student at Beijing Technology and Business University.Jianchi TianJianchi Tian is a postgraduate student at Chinese Academy of Sciences and University of Chinese Academy of Sciences.Yan SunYan Sun is the professor of Psychology at Chinese Academy of Sciences and University of Chinese Academy of Sciences.Meijun MengMeijun Meng is a postgraduate student at Beijing Technology and Business University.
{"title":"How to win public support for financial climate policies: both climate anxiety and economic anticipation work","authors":"Yang Li, Yuxuan Liang, Jianchi Tian, Yan Sun, Meijun Meng","doi":"10.1080/17565529.2023.2266420","DOIUrl":"https://doi.org/10.1080/17565529.2023.2266420","url":null,"abstract":"ABSTRACTConsidering the dual objectives of financial climate policies (such as carbon tax) -mitigating climate change and supporting economic growth, our paper aims to discover the unique process of increasing support for financial climate policies, which was a lack of attention before. Building on the structural equation modelling analysis of a nationwide longitudinal survey including 2322 valid samples in China, this research finds the positive influence of climate anxiety and economic anticipation on the support for financial climate policies, driven by the enhancement of perceived win-win benefits of policies. The findings provide researchers with a new perspective in understanding public support for financial climate policies and the psychological process underneath. Policy-makers could benefit from the findings by strategically managing the climate anxiety and economic anticipation of the public and raising public awareness of personal benefits beyond climate benefits when implementing financial climate policies.KEYWORDS: Climate changefinancial climate policiesclimate anxietyeconomic anticipationperceived benefit Disclosure statementNo potential conflict of interest was reported by the author(s).Additional informationFundingThis work was supported by the National Natural Science Foundation of China [grant number 71902005].Notes on contributorsYang LiYang Li is an associate professor of Marketing at Beijing Technology and Business University.Yuxuan LiangYuxuan Liang is a postgraduate student at Beijing Technology and Business University.Jianchi TianJianchi Tian is a postgraduate student at Chinese Academy of Sciences and University of Chinese Academy of Sciences.Yan SunYan Sun is the professor of Psychology at Chinese Academy of Sciences and University of Chinese Academy of Sciences.Meijun MengMeijun Meng is a postgraduate student at Beijing Technology and Business University.","PeriodicalId":47734,"journal":{"name":"Climate and Development","volume":"26 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134957300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
While the Pacific region stands at the forefront of climate change related impacts, we need to hear from those most affected especially in terms of the mental health and wellbeing impacts for our Pacific communities. This exploratory study is led and carried out by Pacific and Indigenous researchers with Pacific peoples and seeks to place Pacific voices front and centre of its practice and analysis. This multi-country study was undertaken with Pacific experts and knowledge holders in Aotearoa New Zealand, the Cook Islands and Niuē. This paper foregrounds Pacific perspectives, and considers how western concepts, such as eco- and climate anxiety, can be best applied to understand the mental distress of climate change for Pacific peoples. We demonstrate that there is a deep interconnection between climate change and mental health and wellbeing, and the impacts of this link has been cultural nuanced and defined by and for Pacific peoples.
{"title":"Anchored in pacific protocols – climate change, mental health and wellbeing","authors":"Christina Newport, Jemaima Tiatia-Siau, KDee Aimiti Ma'ia'i, Yvonne Underhill-Sem, Alistair Woodward","doi":"10.1080/17565529.2023.2255563","DOIUrl":"https://doi.org/10.1080/17565529.2023.2255563","url":null,"abstract":"While the Pacific region stands at the forefront of climate change related impacts, we need to hear from those most affected especially in terms of the mental health and wellbeing impacts for our Pacific communities. This exploratory study is led and carried out by Pacific and Indigenous researchers with Pacific peoples and seeks to place Pacific voices front and centre of its practice and analysis. This multi-country study was undertaken with Pacific experts and knowledge holders in Aotearoa New Zealand, the Cook Islands and Niuē. This paper foregrounds Pacific perspectives, and considers how western concepts, such as eco- and climate anxiety, can be best applied to understand the mental distress of climate change for Pacific peoples. We demonstrate that there is a deep interconnection between climate change and mental health and wellbeing, and the impacts of this link has been cultural nuanced and defined by and for Pacific peoples.","PeriodicalId":47734,"journal":{"name":"Climate and Development","volume":"19 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135340414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}