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Nanocrocin Protective Effects on Paraquat-Induced Oxidative Stress in the MRC-5 Cell Line. 纳米霉素对百草枯诱导的 MRC-5 细胞系氧化应激的保护作用
IF 2.1 3区 环境科学与生态学 Q1 DEVELOPMENT STUDIES Pub Date : 2024-04-01 Epub Date: 2022-11-17 DOI: 10.1007/s12291-022-01096-y
Akram Oftadeh Harsin, Farzin Firozian, Amir Nili Ahmadabadi, Meysam Soleimani, Akram Ranjbar

Paraquat (PQ) herbicide poisoning is a severe medical problem in developing countries without suitable therapy. This study aimed to investigate the effects of crocin (CCN) and nano crocin (NCCN) on PQ -induced toxicity in the MRC-5 cell line. The results showed that the particle size of NCCN was 140.3 ± 18.0 nm, and the zeta potential of the optimal crocin-loaded niosomes was 23.4 ± 2.8 mV. The NCCN was more effective than CCN in the inhibition of PQ-induced toxicity. Treatment of the MRC-5 cells leads to a decrease in ROS and an increase in SOD, CAT, GPX, and TAC levels in PQ-CCN and PQ-NCCN groups compared with the PQ group. These changes tended to be positively associated with the NCCN compared to CCN. Overall, NCCN was more effective than crocin in treating PQ-induced toxicity in vitro and deserved further preclinical consideration.

百草枯(PQ)除草剂中毒在发展中国家是一个严重的医疗问题,但却没有合适的治疗方法。本研究旨在探讨巴豆素(CCN)和纳米巴豆素(NCCN)对百草枯诱导的 MRC-5 细胞系毒性的影响。结果表明,NCCN的粒径为140.3 ± 18.0 nm,最佳巴豆毒素载体的zeta电位为23.4 ± 2.8 mV。在抑制 PQ 诱导的毒性方面,NCCN 比 CCN 更有效。与 PQ 组相比,PQ-CCN 组和 PQ-NCCN 组处理 MRC-5 细胞后,ROS 水平下降,SOD、CAT、GPX 和 TAC 水平上升。与 CCN 相比,这些变化往往与 NCCN 呈正相关。总体而言,NCCN 在治疗 PQ 诱导的体外毒性方面比巴豆苷更有效,值得进一步进行临床前研究。
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引用次数: 0
Concealing, naming, or tackling inequalities? Art, culture and (In)justice at COP27 隐藏、命名还是解决不平等问题?COP27 上的艺术、文化与(不)公正
IF 4.3 3区 环境科学与生态学 Q1 DEVELOPMENT STUDIES Pub Date : 2024-01-05 DOI: 10.1080/17565529.2023.2298805
Linn Burchert
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引用次数: 0
Violent transitions: towards a political ecology of coal and hydropower in India 暴力过渡:走向印度煤炭和水电政治生态学
IF 4.3 3区 环境科学与生态学 Q1 DEVELOPMENT STUDIES Pub Date : 2023-12-22 DOI: 10.1080/17565529.2023.2264259
Mukul Kumar
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引用次数: 0
Valuing a values-based approach for assessing loss and damage 采用基于价值的方法评估损失和损害
IF 4.3 3区 环境科学与生态学 Q1 DEVELOPMENT STUDIES Pub Date : 2023-12-13 DOI: 10.1080/17565529.2023.2289533
Douwe van Schie, K. McNamara, Merewalesi Yee, A. Mirza, Ross Westoby, M. M. Nand, Rawnak Jahan Khan Ranon, R. Clissold, Simon Anderson, S. Huq
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引用次数: 0
Feminization of hunger in climate change: linking rural women’s health and wellbeing in India 气候变化中的饥饿女性化:将印度农村妇女的健康与福祉联系起来
IF 4.3 3区 环境科学与生态学 Q1 DEVELOPMENT STUDIES Pub Date : 2023-12-13 DOI: 10.1080/17565529.2023.2282486
Itishree Pattnaik, Kuntala Lahiri-Dutt
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引用次数: 0
We used to ‘chase the rains’ away in the past: the role of cultural values and beliefs in shaping farmers’ perceptions of climate variability and change in North-west Ghana 我们过去曾'赶走'雨水:文化价值观和信仰在塑造加纳西北部农民对气候多变性和气候变化的认识方面的作用
IF 4.3 3区 环境科学与生态学 Q1 DEVELOPMENT STUDIES Pub Date : 2023-12-10 DOI: 10.1080/17565529.2023.2287744
George Dakurah, Prince Osei-Wusu Adjei, Henny Osbahr
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引用次数: 0
The developmental state's legacy and corporate carbon emission performance: evidence from Taiwanese firms between 2014 and 2018 发展型国家的遗产与企业碳排放绩效:来自 2014 年至 2018 年台湾企业的证据
IF 4.3 3区 环境科学与生态学 Q1 DEVELOPMENT STUDIES Pub Date : 2023-12-01 DOI: 10.1080/17565529.2023.2287743
C. Pien, Chia-wei Chao, Kuei-tien Chou
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引用次数: 0
Climate adaptation and resilience indices for the Caribbean region: an assessment of four leading indices 加勒比地区气候适应性和复原力指数:对四个主要指数的评估
IF 4.3 3区 环境科学与生态学 Q1 DEVELOPMENT STUDIES Pub Date : 2023-12-01 DOI: 10.1080/17565529.2023.2282482
Richard Grant, S. S. Roy, Camilla Jimenez Zablah, Perla Aquino, Madisyn Simpson, Paula Viala
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引用次数: 0
How to win public support for financial climate policies: both climate anxiety and economic anticipation work 如何赢得公众对金融气候政策的支持:气候焦虑和经济预期都有效
3区 环境科学与生态学 Q1 DEVELOPMENT STUDIES Pub Date : 2023-11-14 DOI: 10.1080/17565529.2023.2266420
Yang Li, Yuxuan Liang, Jianchi Tian, Yan Sun, Meijun Meng
ABSTRACTConsidering the dual objectives of financial climate policies (such as carbon tax) -mitigating climate change and supporting economic growth, our paper aims to discover the unique process of increasing support for financial climate policies, which was a lack of attention before. Building on the structural equation modelling analysis of a nationwide longitudinal survey including 2322 valid samples in China, this research finds the positive influence of climate anxiety and economic anticipation on the support for financial climate policies, driven by the enhancement of perceived win-win benefits of policies. The findings provide researchers with a new perspective in understanding public support for financial climate policies and the psychological process underneath. Policy-makers could benefit from the findings by strategically managing the climate anxiety and economic anticipation of the public and raising public awareness of personal benefits beyond climate benefits when implementing financial climate policies.KEYWORDS: Climate changefinancial climate policiesclimate anxietyeconomic anticipationperceived benefit Disclosure statementNo potential conflict of interest was reported by the author(s).Additional informationFundingThis work was supported by the National Natural Science Foundation of China [grant number 71902005].Notes on contributorsYang LiYang Li is an associate professor of Marketing at Beijing Technology and Business University.Yuxuan LiangYuxuan Liang is a postgraduate student at Beijing Technology and Business University.Jianchi TianJianchi Tian is a postgraduate student at Chinese Academy of Sciences and University of Chinese Academy of Sciences.Yan SunYan Sun is the professor of Psychology at Chinese Academy of Sciences and University of Chinese Academy of Sciences.Meijun MengMeijun Meng is a postgraduate student at Beijing Technology and Business University.
摘要考虑到金融气候政策(如碳税)的双重目标——减缓气候变化和支持经济增长,本文旨在发现以往缺乏关注的金融气候政策支持增加的独特过程。本文通过对全国2322个有效样本的纵向调查进行结构方程建模分析,发现气候焦虑和经济预期对金融气候政策支持的正向影响,其驱动因素是政策感知共赢效益的增强。这一发现为研究人员理解公众对金融气候政策的支持及其背后的心理过程提供了一个新的视角。政策制定者可以通过战略性地管理公众的气候焦虑和经济预期,并在实施金融气候政策时提高公众对气候利益之外的个人利益的认识,从而从研究结果中受益。关键词:气候变化金融气候政策气候焦虑经济预期感知利益披露声明作者未报告潜在利益冲突。本研究得到国家自然科学基金资助[批准号:71902005]。作者简介杨力,北京工商大学市场营销学副教授。梁宇轩,北京工商大学研究生。田建池,中国科学院、中国科学院大学研究生。孙岩,中国科学院、中国科学院大学心理学教授。孟美君,北京工商大学研究生。
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引用次数: 0
Anchored in pacific protocols – climate change, mental health and wellbeing 以太平洋议定书为基础——气候变化、心理健康和福祉
3区 环境科学与生态学 Q1 DEVELOPMENT STUDIES Pub Date : 2023-11-08 DOI: 10.1080/17565529.2023.2255563
Christina Newport, Jemaima Tiatia-Siau, KDee Aimiti Ma'ia'i, Yvonne Underhill-Sem, Alistair Woodward
While the Pacific region stands at the forefront of climate change related impacts, we need to hear from those most affected especially in terms of the mental health and wellbeing impacts for our Pacific communities. This exploratory study is led and carried out by Pacific and Indigenous researchers with Pacific peoples and seeks to place Pacific voices front and centre of its practice and analysis. This multi-country study was undertaken with Pacific experts and knowledge holders in Aotearoa New Zealand, the Cook Islands and Niuē. This paper foregrounds Pacific perspectives, and considers how western concepts, such as eco- and climate anxiety, can be best applied to understand the mental distress of climate change for Pacific peoples. We demonstrate that there is a deep interconnection between climate change and mental health and wellbeing, and the impacts of this link has been cultural nuanced and defined by and for Pacific peoples.
虽然太平洋地区站在气候变化相关影响的最前沿,但我们需要听取受影响最严重的人的意见,特别是在对我们太平洋社区的心理健康和福祉影响方面。这项探索性研究由太平洋和土著研究人员与太平洋人民一起领导和开展,旨在将太平洋的声音置于其实践和分析的前沿和中心。这项多国研究是与新西兰奥特罗阿、库克群岛和纽伊的太平洋专家和知识持有者一起进行的。本文从太平洋的角度出发,考虑如何最好地应用西方的概念,如生态和气候焦虑,来理解太平洋人民因气候变化而遭受的精神痛苦。我们证明,气候变化与心理健康和福祉之间存在着深刻的联系,这种联系的影响在文化上是微妙的,并由太平洋人民定义。
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引用次数: 0
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