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Examining the Relationship Between Community Resources and Early Disability Identification: Variation by Child Race or Ethnicity. 社区资源与早期残疾识别的关系研究:儿童种族或民族差异。
IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-01 Epub Date: 2025-08-16 DOI: 10.1007/s11121-025-01829-4
J LoCasale-Crouch, T Lenahan, Z Shea, J Whittaker, Y Zhang, B Duyile, Y Xu, A Williford

Early identification and intervention support for children with disabilities improve their cognitive, educational, and social outcomes. Studies show that disability identification varies by child race and ethnicity, with children from historically marginalized populations being less likely to be identified during early childhood, where identification tends to happen in the community. One major factor that varies across communities is their resources, broadly defined as the environmental, social, and economic factors within a geographically defined area. While extensive evidence exists noting inequitable distribution of community resources by race and ethnicity, little research has examined whether community resources are associated with differential early disability identification rates. This study explored the association between the availability of community resources and early disability identification and whether it varied by child race or ethnicity. Leveraging 2019 statewide data collected through the Virginia Department of Education (VDOE), we combined information about 91,210 incoming kindergarteners with the Child Opportunity Index 2.0 (COI), a measure of community resources known to be associated with child development. After controlling for multiple covariates, children entering kindergarten at schools in higher-resourced communities were more likely to be identified with a disability prior to kindergarten. Although access to community resources and early disability identification rates varied by child race and/or ethnicity, the interaction effect was not significant. This study has implications for viewing community resources as potential malleable factors to address children's varying needs prior to the start of formal schooling.

对残疾儿童的早期识别和干预支持可以改善他们的认知、教育和社会成果。研究表明,残疾鉴定因儿童的种族和民族而异,来自历史上被边缘化人群的儿童在儿童早期被鉴定的可能性较小,而儿童早期鉴定往往发生在社区中。不同社区之间存在差异的一个主要因素是其资源,广义上定义为地理上确定的区域内的环境、社会和经济因素。虽然存在大量证据表明社区资源按种族和民族分配不公平,但很少有研究调查社区资源是否与不同的早期残疾识别率有关。本研究探讨了社区资源的可用性与早期残疾识别之间的关系,以及它是否因儿童种族或民族而异。利用通过弗吉尼亚州教育部(VDOE)收集的2019年全州数据,我们将91210名即将入学的幼儿园儿童的信息与儿童机会指数2.0 (COI)相结合,这是一种衡量与儿童发展相关的社区资源的指标。在控制了多个协变量后,在资源较丰富的社区进入幼儿园的儿童更有可能在幼儿园之前被识别为残疾。虽然获得社区资源和早期残疾识别率因儿童种族和/或民族而异,但交互作用并不显著。这项研究对将社区资源视为潜在的可塑性因素,以解决儿童在正式学校教育开始之前的不同需求具有启示意义。
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引用次数: 0
Addressing Suicide and Mental Health Through Universal Childhood Intervention: Results from The Seattle Social Development Project. 通过普遍儿童干预解决自杀和心理健康问题:来自西雅图社会发展项目的结果。
IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-01 Epub Date: 2025-10-18 DOI: 10.1007/s11121-025-01834-7
Karl G Hill, Christine M Steeger, Marina Epstein, Jennifer A Bailey, J David Hawkins

The objective of this study is to examine cross-over effects of the Raising Healthy Children universal childhood preventive intervention on adult suicide behaviors and related mental health. A nonrandomized controlled trial was conducted in elementary schools serving higher-risk areas in Seattle, Washington (during ages 6-13, grades 1-6) and followed up at ages 21-39. The panel originated in Seattle but was followed in and out of state. This study examines participants who had been in the intervention (n = 156) vs. control (n = 220) conditions in grades 1-6. The intervention provided teachers with methods of classroom management, parents with family management skills, and children with social-emotional skills training. Outcomes examined were ever suicide ideation, attempt, or completion, and DSM-IV-based criterion counts for depression, generalized anxiety disorder, PTSD, and social phobia across 6 waves, ages 21-39. At follow-up, the intervention group showed significantly lower suicide ideation and behavior, depression, generalized anxiety disorder, PTSD, and social phobia than the control group. Universal childhood preventive intervention can reduce suicide ideation and behaviors and related mental health problems in adulthood. Clinical Trials.gov ID: NCT04075019.

摘要本研究旨在探讨《养育健康儿童》普及儿童预防干预对成人自杀行为及相关心理健康的交叉影响。一项非随机对照试验在华盛顿州西雅图服务于高风险地区的小学进行(6-13岁,1-6年级),并对21-39岁的学生进行随访。该小组起源于西雅图,但在州内外都受到了关注。本研究调查了1-6年级干预组(n = 156)和对照组(n = 220)的参与者。该干预为教师提供了课堂管理方法,为家长提供了家庭管理技能,为儿童提供了社会情感技能培训。检查的结果是曾经有过自杀念头、企图或自杀未遂,并以dsm - iv为基础的标准计算了21-39岁人群中抑郁症、广泛性焦虑症、创伤后应激障碍和社交恐惧症的6个阶段。在随访中,干预组的自杀意念和行为、抑郁、广泛性焦虑障碍、创伤后应激障碍和社交恐惧症明显低于对照组。普遍的儿童预防干预可以减少成年后的自杀意念和行为以及相关的心理健康问题。临床试验。gov ID: NCT04075019。
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引用次数: 0
Modifications of a Parenting Program in the Context of Scaling-Up and Scaling-Out: Documenting Furaha Teens in Tanzania Using FRAME. 在扩大和扩大的背景下父母教育计划的修改:使用框架记录坦桑尼亚富拉哈青少年。
IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-01 Epub Date: 2025-10-30 DOI: 10.1007/s11121-025-01852-5
Yulia Shenderovich, Mackenzie Martin, Jamie M Lachman, Samwel Mgunga, Esther Ndyetabura, Joyce Wamoyi

Program adaptations or modifications are often necessary to suit local contexts, populations, and resources available. Despite the frequency with which program modifications are made in practice, they are rarely systematically recorded and reported comprehensively, particularly in the context of scale-up delivery led by implementers and in low- and middle-income countries. We use the FRAME framework to document the modifications of a parenting program called Parenting for Lifelong Health for Parents and Adolescents, locally known as Furaha Teens, which was delivered to over 30,000 families in Tanzania in 2020-2021. We draw on thematic analysis of 12 focus groups and 67 semi-structured interviews with program facilitators, coaches, coordinators, and managers (164 participants). Both proactive and reactive modifications were made to the program context and content. Proactive modifications included delivering the program as part of a wider package of services for families with adolescent girls, focused on HIV prevention, and adding HIV-related content. Both proactive and reactive modifications were made to make the material more acceptable to participants, such as by translating into local languages. Modifications to condense the number and frequency of sessions were reactively made by implementers to meet delivery timelines, particularly due to COVID-related closures. Study findings suggest that a range of program modifications may be required to scale programs to large cohorts as well as new contexts. To ensure successful delivery at scale, funders can support implementers in learning from the modifications and encouraging reflection on whether and how modifications affect program fidelity.

为了适应当地环境、人口和可用资源,通常需要对程序进行调整或修改。尽管在实践中经常对规划进行修改,但很少有系统地记录和全面报告,特别是在由执行者领导的扩大交付的背景下以及在低收入和中等收入国家。我们使用FRAME框架记录了一项名为“父母和青少年终身健康育儿”的育儿计划的修改情况,该计划在当地被称为Furaha Teens,于2020-2021年向坦桑尼亚的3万多个家庭提供了该计划。我们对12个焦点小组进行了专题分析,并对项目协调员、教练、协调员和管理者(164名参与者)进行了67次半结构化访谈。对项目背景和内容进行了主动和被动的修改。积极的修改包括将该方案作为更广泛的一揽子服务的一部分提供给有青春期女孩的家庭,重点是预防艾滋病毒,并增加与艾滋病毒有关的内容。进行了主动和被动的修改,使材料更容易被参与者接受,例如将其翻译成当地语言。实施者积极作出修改,缩短会议次数和频率,以满足交付时间表,特别是由于与covid - 19相关的关闭。研究结果表明,可能需要进行一系列的程序修改,以将程序扩展到大型队列以及新的环境中。为了确保大规模的成功交付,资助者可以支持执行者从修改中学习,并鼓励反思修改是否以及如何影响项目的保真度。
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引用次数: 0
Qualitative Mediation Analysis: an Important Method for Exploring Mediating Mechanisms in Prevention Science. 质性中介分析:预防科学探索中介机制的重要方法。
IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-01 Epub Date: 2025-08-23 DOI: 10.1007/s11121-025-01836-5
Joanna J Kim, David P MacKinnon

Mediating variables serve a primary role in devising intervention theories and applying them to practice. Prevention scientists have repeatedly called for understanding how and why an independent variable (X; e.g., intervention) is related to a dependent variable (Y; e.g., drug use). Quantitative mediation is used to describe mediating variables that intervene in the causal path from X to Y. Most methodological development for mediation analysis has focused on statistical methods and the assumptions necessary for valid application of these statistical methods. The current paper describes how qualitative methods extend into mediation research and the unique strength of qualitative mediation in identifying potential mediators and mechanisms of change not previously hypothesized. Taking examples from prevention research, we outline how qualitative mediation generates unique and complementary information about mediating mechanisms that may only be available through interviews, focus groups, observation, archival analysis, and other qualitative methodology. We briefly describe cautions when using qualitative mediation including reliance of retrospective reports, potential to influence interviewees, and selective sampling. We underline how qualitative mediation analysis is particularly well suited for exploratory studies and extracting mechanisms of action for new or adapted interventions in prevention science.

中介变量在设计干预理论并将其应用于实践中起着主要作用。预防科学家一再呼吁了解自变量(X,例如干预)与因变量(Y,例如药物使用)之间的关系。定量中介用于描述干预从X到y的因果路径的中介变量。大多数中介分析的方法发展都集中在统计方法和有效应用这些统计方法所必需的假设上。本文描述了定性方法如何扩展到中介研究中,以及定性中介在识别潜在中介和以前未假设的变化机制方面的独特优势。以预防研究为例,我们概述了定性调解如何产生关于调解机制的独特和补充信息,这些信息可能只能通过访谈、焦点小组、观察、档案分析和其他定性方法获得。我们简要描述了使用定性中介时的注意事项,包括对回顾性报告的依赖,对受访者的潜在影响以及选择性抽样。我们强调定性中介分析如何特别适合于探索性研究和提取预防科学中新的或适应性干预措施的作用机制。
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引用次数: 0
Schools' Readiness for Child Sexual Abuse Prevention Education: an Overview of Theoretical Models. 学校防范儿童性虐待教育的准备:理论模型综述。
IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-01 Epub Date: 2025-10-01 DOI: 10.1007/s11121-025-01843-6
Yuejiao Wu, Kerryann Walsh, Sonia L J White, Lyra L'Estrange

Schools' readiness appears an important factor influencing their implementation of violence prevention programs. This review was undertaken to identify, describe, and compare existing theoretical readiness models and their strengths and limitations, and to select an appropriate theoretical model to underpin the study of schools' readiness for child sexual abuse (CSA) prevention education. This, in turn, would guide development of a new instrument to assess schools' readiness for CSA prevention. Searches were conducted from September to December 2022 in ERIC, PsychINFO, PubMed, Science Direct, Sociological Abstracts, Web of Science, and Google Scholar, and handsearches were made in academic journals. We included peer-reviewed papers published in English that reported the development, testing, or use of a theoretical readiness model at an organizational level. We identified three candidate groups of theoretical models from 85 papers: the community readiness model, the multidimensional child maltreatment prevention readiness model, and organizational readiness for change theories. These models were appraised using four criteria for selecting implementation science theories and frameworks (Birken et al. 2017). We propose Weiner's (2009) organizational readiness for change as the most plausible theoretical model with both descriptive and analytical potential for assessing schools' readiness for child sexual abuse prevention education, and discuss the conceptual and empirical strengths and weaknesses of the identified models. The review has demonstrated the utility of applying criteria (Birken et al. 2017) to appraise and select theoretical readiness models in CSA prevention education and other implementation research areas.

学校是否做好准备似乎是影响其实施暴力预防方案的一个重要因素。本综述旨在识别、描述和比较现有的理论准备模型及其优势和局限性,并选择合适的理论模型来支持学校对儿童性虐待(CSA)预防教育的准备研究。反过来,这将指导开发一种新的工具,以评估学校预防CSA的准备情况。检索于2022年9月至12月在ERIC、PsychINFO、PubMed、Science Direct、Sociological Abstracts、Web of Science和b谷歌Scholar中进行,并在学术期刊中进行手工检索。我们收录了用英语发表的同行评审论文,这些论文报告了在组织层面上理论准备模型的开发、测试或使用。我们从85篇论文中确定了三个候选理论模型组:社区准备模型、多维儿童虐待预防准备模型和组织变革准备理论。这些模型使用选择实施科学理论和框架的四个标准进行评估(Birken et al. 2017)。我们提出Weiner(2009)的组织变革准备作为最合理的理论模型,具有描述性和分析潜力,可用于评估学校对儿童性虐待预防教育的准备情况,并讨论已确定模型的概念和经验优势和弱点。该综述证明了应用标准(Birken et al. 2017)在CSA预防教育和其他实施研究领域评估和选择理论准备模型的效用。
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引用次数: 0
Supplementing Program Profiles in Evidence Clearinghouses with Insights for Practice: a Qualitative Investigation of Application to Youth Mentoring Programs in CrimeSolutions. 以实践见解补充证据交换所的项目概况:犯罪解决方案中青年指导计划应用的定性调查。
IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-01 Epub Date: 2025-10-08 DOI: 10.1007/s11121-025-01841-8
Aisha N Griffith, Julia Pryce, David L DuBois, Timothy Brezina, Kelly E Stewart, Michael Garringer

Evidence-based program repositories have been designed to help practitioners in their decision-making. Most repositories supplement summaries of effectiveness evidence with information intended to assist with implementation of each included program (e.g., training costs). It is less common for guidance to be included to support translation of findings for a broader range of purposes, such as enhancing related programs already in place. To help address this gap within the area of youth mentoring, the National Mentoring Resource Center has appended "Insights for Mentoring Practitioners" to profiles of 47 mentoring programs included in the CrimeSolutions.gov repository of the National Institute of Justice. We qualitatively analyzed these commentaries to elucidate themes across them that can inform the development and improvement of mentoring programs. Themes included (1) ensuring alignment across program goals, design, implementation, and evaluation; (2) connecting the intervention to mentees' home, parents, and larger environment; (3) tailoring mentor engagement and support to effectively serve youth; and (4) optimizing the role of mentoring within multi-component programs. Discussion focuses on how findings inform the improvement of mentoring programs, and how content geared toward the translation of evidence to practice could enhance and improve evidence repositories.

基于证据的程序存储库被设计用来帮助从业者做出决策。大多数存储库用信息补充有效性证据的摘要,这些信息旨在帮助实现每个包括的项目(例如,培训成本)。不太常见的情况是,为更广泛的目的(如加强现有的相关项目)提供指导,以支持对研究结果的翻译。为了帮助解决青年辅导领域的这一差距,国家辅导资源中心在国家司法研究所的犯罪解决方案网站(crimessolutions .gov)中收录的47个辅导项目的简介中附加了“辅导从业者的见解”。我们定性地分析了这些评论,以阐明它们之间的主题,这些主题可以为指导计划的发展和改进提供信息。主题包括(1)确保项目目标、设计、实施和评估的一致性;(2)将干预与被指导者的家庭、父母和更大的环境联系起来;(3)量身定制导师参与和支持,有效服务青年;(4)优化师徒在多组件项目中的作用。讨论的重点是研究结果如何为指导项目的改进提供信息,以及将证据转化为实践的内容如何加强和改进证据库。
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引用次数: 0
Preschool Expulsion Risk Factors: Teachers' Ratings of Preschoolers' Challenging Behaviors Vary by the Cooperativeness of their Parents. 幼儿驱逐危险因素:教师对幼儿挑战行为的评价随家长合作程度的不同而不同。
IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-01 Epub Date: 2025-09-15 DOI: 10.1007/s11121-025-01838-3
Courtney A Zulauf-McCurdy, Rechele Brooks, Andrew N Meltzoff

Preschool children in the United States are expelled at a rate of about 250 per day with a disproportionate number being Black children. There is a need to better understand how to prevent preschool expulsion. Using a random-assignment experiment, preschool teachers (N = 95; 92% female; 61% White) were assigned to one of eight conditions: child race (Black vs. White) × child gender (boy vs. girl) × parental cooperativity (cooperative vs. uncooperative). Teachers read two controlled vignettes: one about a child and one about that child's parents. The child vignette described the child's challenging classroom behavior (identical behavior for all children); the parent vignette described a subsequent meeting with the child's parents (half of the parents were described as uncooperative with the teacher and half as cooperative). After each vignette, teachers were asked to complete sections of the Preschool Expulsion Risk Measure (PERM) to assess two known risk factors for preschool expulsion: (a) teachers' perception of the disruptiveness of the child's classroom behavior and (b) teachers' feelings of hopelessness about changing the child's behavior. Even though the child's challenging behavior was controlled (by experimental design), teachers' construal of the child's behavior and teachers' feelings of hopelessness towards the child were significantly influenced by the descriptions of parental cooperation. Variations in results by child race and child gender are also reported. Findings indicate that teachers' perceptions of parents may be a particularly important factor to prevent children from preschool expulsion.

在美国,学龄前儿童每天被开除的人数约为250人,其中黑人儿童的比例不成比例。有必要更好地了解如何防止学龄前儿童被驱逐。采用随机分配实验,95名幼儿教师(92%为女性,61%为白人)被分配到8个条件中的一个:儿童种族(黑人与白人)×儿童性别(男孩与女孩)×父母合作(合作与不合作)。老师们阅读了两篇对照小短文:一篇是关于一个孩子的,另一篇是关于孩子父母的。儿童小插图描述了儿童具有挑战性的课堂行为(所有儿童的行为相同);家长小短文描述了随后与孩子父母的会面(一半的父母被描述为不与老师合作,一半的父母被描述为合作)。在每个小插曲之后,教师被要求完成学前驱逐风险测量(PERM)的部分,以评估两个已知的学前驱逐风险因素:(a)教师对儿童课堂行为破坏性的感知和(b)教师对改变儿童行为的绝望感。即使儿童的挑战行为被控制(通过实验设计),教师对儿童行为的解释和教师对儿童的绝望感也受到父母合作描述的显著影响。还报告了儿童种族和儿童性别的结果差异。研究结果表明,教师对家长的看法可能是防止儿童学龄前被驱逐的一个特别重要的因素。
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引用次数: 0
Why Do Student Perceptions of Teachers' Condemning of the Bullying and Empathy-Raising Lead to Intention to Stop Bullying? The Role of Emotions. 为什么学生对教师谴责欺凌和移情培养的认知会导致停止欺凌的意图?情绪的作用。
IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-01 Epub Date: 2025-09-12 DOI: 10.1007/s11121-025-01839-2
Eerika Johander, Tiina Turunen, Claire F Garandeau, Christina Salmivalli

Two strategies used by teachers in targeted antibullying interventions, condemning of the bullying behavior and empathy-raising, have been shown to positively predict bullies' intention to stop bullying. However, the mechanism through which they work remains unknown. We tested whether moral emotions (guilt and shame), and empathic emotion (sadness) mediated the effects of students' perceptions of teachers' condemning and empathy-raising messages on their intention to stop bullying. A normative sample of 277 seventh-grade students (Mage = 12.93, SD = 0.49; 47% female) was asked to imagine having bullied a peer and being invited to a discussion with a teacher. They saw a video vignette with one of three messages: condemning, empathy-raising or a combination of both. Analyses revealed that the effects of perceived condemning of the bullying behavior on intention to stop were primarily mediated by feelings of guilt, while the effects of perceived empathy-raising were mediated by both sadness and guilt. Shame was not associated with intention to stop bullying and did not mediate the effects of the perceptions. These findings suggest that targeted anti-bullying interventions should aim to evoke guilt and sadness (or empathic concern) rather than shame.

教师在有针对性的反欺凌干预中使用的两种策略,谴责欺凌行为和移情培养,已被证明对欺凌者停止欺凌的意图有正向预测作用。然而,它们起作用的机制尚不清楚。我们测试了道德情绪(内疚和羞耻)和共情情绪(悲伤)是否介导了学生对教师谴责和提高共情信息的感知对他们停止欺凌的意图的影响。277名七年级学生(Mage = 12.93, SD = 0.49; 47%为女生)被要求想象自己欺负过同学,并被邀请与老师进行讨论。他们看了一段视频,上面有三种信息之一:谴责、同情或两者兼而有之。分析发现,感知谴责霸凌行为对停止意向的影响主要由内疚感介导,而感知移情提高对停止意向的影响主要由悲伤和内疚感介导。羞耻与停止欺凌的意图无关,也没有调节感知的影响。这些发现表明,有针对性的反欺凌干预措施应该旨在唤起内疚和悲伤(或共情关怀),而不是羞耻。
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引用次数: 0
Development and Validation of an Electronic Health Record-Derived Prediction Model for Preventing COVID-19 Hospitalization and Death. 预防COVID-19住院和死亡的电子健康记录预测模型的开发和验证
IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-10-20 DOI: 10.1007/s11121-025-01844-5
R Yates Coley, Rachel Hays, Roy E Pardee, Sharon Fuller, Kristine Rogers, Claire L Allen, David E Arterburn, Robert K Frazier, Daniel J Kent, Sophia Mun, Tolani Mwatha, Paul Thottingal, Emily O Westbrook

Hospitalization and death following COVID-19 infection continue to pose a major public health concern and place strain on health system resources. Outpatient antiviral medication can reduce the risk of COVID-19 hospitalization and death for those at risk of poor outcomes, but identifying high-risk populations who may benefit most from treatment is challenging. The objective of this study was to develop and validate a prediction model for the composite outcome of hospitalization or death in the 14 days following COVID-19 infection. Our sample included 67,530 COVID-19 infections documented in outpatient care and occurring between April 1, 2020, and November 1, 2022, for 64,529 Kaiser Permanente Washington patients who did not receive outpatient antiviral treatment; 1378 (2.0%) of these infections resulted in hospitalization or death. Our prediction model, estimated using logistic regression with LASSO variable selection and ridge penalization, included 19 risk factors and showed high performance, including an area under the curve of 0.825 (95% confidence interval 0.813-0.836). Among the 10% of infections with the highest risk predictions, the true positive rate was 48% (46-51%) and the positive predictive value was 9.9% (9.2-10.6%). Supplemental analyses confirmed strong model performance across racial and ethnic subgroups and over time. We also present our process for selecting a risk threshold above which to recommend antiviral treatment and discuss considerations for prospective clinical implementation. This project demonstrates that machine learning tools can be used by health systems to deliver timely, targeted secondary prevention to reduce the risk of serious illness or death.

COVID-19感染后的住院和死亡继续构成重大公共卫生问题,并给卫生系统资源带来压力。门诊抗病毒药物治疗可以降低那些预后不良的人因COVID-19住院和死亡的风险,但确定可能从治疗中获益最多的高危人群具有挑战性。本研究的目的是建立并验证COVID-19感染后14天住院或死亡综合结局的预测模型。我们的样本包括门诊护理记录的67,530例COVID-19感染,发生在2020年4月1日至2022年11月1日之间,其中包括64,529名未接受门诊抗病毒治疗的华盛顿凯撒医疗机构患者;其中1378例(2.0%)感染导致住院或死亡。我们的预测模型使用LASSO变量选择和山脊惩罚的逻辑回归估计,包括19个危险因素,并显示出很高的性能,包括曲线下面积为0.825(95%置信区间为0.813-0.836)。在预测风险最高的10%感染中,真阳性率为48%(46 ~ 51%),阳性预测值为9.9%(9.2 ~ 10.6%)。补充分析证实了模型在种族和民族亚群体和时间上的强大表现。我们还介绍了选择风险阈值的过程,高于该阈值推荐抗病毒治疗,并讨论了前瞻性临床实施的考虑因素。该项目表明,机器学习工具可以被卫生系统用于提供及时、有针对性的二级预防,以降低严重疾病或死亡的风险。
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引用次数: 0
Addressing Structural Factors to Prevent Youth Violence Through a Multisector Collaborative Approach. 通过多部门合作方法解决结构性因素以预防青少年暴力。
IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-10-14 DOI: 10.1007/s11121-025-01845-4
Valerie M Thompson, Jomella Watson-Thompson, Donte L Bernard, Lauratu Bah

Youth violence is a significant public health concern with differential impacts on youth who reside in high-burden communities. Structural factors, including institutional practices and policies, contribute to the concentration of youth within neighborhoods where violence is more likely to occur. Across disciplines, scholars have identified structural factors that affect not only the prevalence of violence but also environmental conditions that make violence more likely. Consequently, interventions may fall short of addressing the root causes of violence, perpetuating cycles of harm rather than fostering long-term solutions. It is crucial to advance community and societal level approaches to address macro-level factors influencing youth violence. The Institute of Medicine's Framework for Collaborative Public Health Action suggests that community coalitions may contribute to preventing youth violence by facilitating multisectoral engagement across socioecological levels to promote sustainable change. Guided by this framework, the ThrYve Coalition in Kansas City convened over 40 community partners across 15 sectors to address youth violence (Watson-Thompson et al., 2020). Through a collaborative process, 87 change lever strategies (i.e., strategies to implement program, policy, practice changes) were identified to support community and systems-level improvements aligned with risk and protective factors related to youth violence. Between 2018 and 2022, the ThrYve Coalition implemented more than 199 community changes, addressing social and structural determinants related to youth violence. This study examines the collaborative process for facilitating change as part of a comprehensive community intervention to prevent youth violence.

青年暴力是一个重大的公共卫生问题,对生活在高负担社区的青年有不同的影响。结构性因素,包括体制做法和政策,导致青年集中在更容易发生暴力的社区内。跨学科的学者们已经确定了结构性因素,这些因素不仅影响暴力的流行,而且还影响使暴力更有可能发生的环境条件。因此,干预措施可能无法解决暴力的根源,使伤害的循环永久化,而不是促进长期解决办法。必须推进社区和社会一级的办法,以处理影响青年暴力的宏观因素。医学研究所的《公共卫生合作行动框架》建议,社区联盟可以通过促进跨社会生态层面的多部门参与来促进可持续变革,从而有助于预防青少年暴力。在这一框架的指导下,堪萨斯城的ThrYve联盟召集了15个部门的40多个社区合作伙伴来解决青年暴力问题(Watson-Thompson et al., 2020)。通过合作过程,确定了87项变革杠杆战略(即实施计划、政策和实践变革的战略),以支持社区和系统层面的改进,这些改进与青少年暴力相关的风险和保护因素相一致。在2018年至2022年期间,繁荣联盟实施了199多项社区变革,解决了与青年暴力有关的社会和结构决定因素。本研究探讨了促进变革的合作过程,作为预防青少年暴力的综合社区干预的一部分。
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Prevention Science
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