Sleep Health最新文献_第5页

The relationship between multiple concussions and multidimensional sleep quality in collegiate-aged, active athletes 大学适龄活跃运动员的多次脑震荡与多维睡眠质量之间的关系。

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Sleep Health

Pub Date : 2024-08-01 DOI: 10.1016/j.sleh.2024.04.005

Objectives

Determine the association of cumulative concussion and repetitive head impacts with self-reported sleep quality in healthy collegiate-aged athletes.

Methods

Collegiate-aged athletes (N = 212; mean age 21.00, 62.7% male) completed semistructured interviews for sport and concussion history and the Pittsburgh Sleep Quality Index (PSQI). Number of concussions was retrospectively determined based on the 1993 American Congress of Rehabilitation Medicine (ACRM) criteria; repetitive head impact was measured based on the cumulative years of contact sport exposure. Associations of number of concussions and repetitive head impact exposure with global PSQI score, overall poor (PSQI >5) vs. good sleep, and binarized subscale scores were tested. Secondary analyses were conducted using alternative concussion criteria and metrics of repetitive head impact.

Results

The number of prior concussions was associated with higher PSQI global scores (B(SE) = 0.50(0.13), p < .001). Participants with more concussions were more likely to be poor sleepers (OR = 1.52, p < .001), report poorer sleep quality (OR = 1.29, p = .037), longer sleep latency (OR = 1.34, p = .005), more sleep disturbances (OR = 1.56, p = .001), increased use of sleep medications or sleep aids (OR = 1.35, p = .008), and more sleep-related daily dysfunction (OR = 1.38, p = .002). Similar results were observed for alternative definitions of concussion. No metric of repetitive head impact was associated with any sleep quality metric.

Conclusions

More prior concussions, but not repetitive head impact exposure, are associated with worse self-reported sleep, with subscale analyses showing concussion history associated with multiple aspects of subjective sleep quality rather than sleep quantity. Sleep represents an important factor to consider for future research aimed at characterizing and ultimately preventing adverse long-term health outcomes associated with concussion history.

目标：确定累积性脑震荡和重复性头部撞击与健康大学适龄运动员自我报告的睡眠质量的关系：确定健康大学适龄运动员的累积性脑震荡和重复性头部撞击与自我报告的睡眠质量之间的关系：大学适龄运动员（212 人；平均年龄 21.00 岁，62.7% 为男性）完成了有关运动和脑震荡病史以及匹兹堡睡眠质量指数（PSQI）的半结构化访谈。脑震荡次数根据 1993 年美国康复医学会 (ACRM) 标准进行回顾性测定；重复性头部撞击根据接触体育运动的累积年数进行测量。测试了脑震荡次数和重复性头部撞击与 PSQI 总分、总体睡眠质量差（PSQI >5）与睡眠质量好以及二元化子量表得分之间的关系。使用其他脑震荡标准和重复性头部撞击指标进行了二次分析：结果：既往脑震荡次数与较高的 PSQI 总分相关（B（SE）= 0.50（0.13），P 结论：既往脑震荡次数越多，PSQI 总分就越高，但并不意味着睡眠质量越好：更多的既往脑震荡（而非重复性头部撞击）与自我报告的睡眠质量较差有关，分量表分析表明脑震荡史与主观睡眠质量的多个方面而非睡眠量有关。睡眠是未来研究中需要考虑的一个重要因素，这些研究旨在确定脑震荡病史的特征，并最终预防与脑震荡病史相关的不良长期健康后果。

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引用次数: 0

Instructional approach, sleep, and perceived academic well-being in adolescents during COVID-19: Evidence from the NESTED study COVID-19期间青少年的教学方法、睡眠和学习幸福感：来自 NESTED 研究的证据。

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Sleep Health

Pub Date : 2024-08-01 DOI: 10.1016/j.sleh.2024.04.006

Objectives

At the peak of COVID-19, adolescent life was disrupted as schools adapted their instructional approaches such as online, in-person, or hybrid instruction. We and others have previously commented on how these shifts facilitated longer, later and (more developmentally appropriate) sleep. Here, we report how sleep contributed to associations between remote instruction and broader academic well-being (e.g., cognitive function, school connectedness, and stress).

Methods

Adolescents from all 50 U.S. states (n = 4068) completed online self-report surveys in fall 2020. Instructional approach was operationalized from fully in-person instruction to fully asynchronous online education. Sleep parameters included sleep timing and duration, sleep disturbances, and sleep-related impairments. Perceived academic well-being was defined as cognitive function, school connectedness, and school-related stress. Sleep and perceived academic well-being are examined across instructional approaches, in their association, and in structural models.

Results

Sleep and perceived academic well-being differed between hybrid and online instruction groups. Less variable or disturbed sleep was associated both with in-person instruction, and with positive outcomes in cognitive function, school connectedness, and stress domains. Sleep mediated a substantial portion of variance in perceived academic well-being attributable to instructional approach.

Conclusion

These data highlight the need to protect both healthy sleep and in-person instruction. Appropriate sleep timing and duration, fewer sleep disturbances and sleep-related impairments accounted for a substantial degree of variance in the association between remote instruction on academic outcomes. While many students experienced “lost learning” because of COVID-19, this study joins a broader discussion of ensuring developmentally appropriate school-start times to support both sleep and achievement.

目标：在 COVID-19 高峰期，由于学校调整了教学方法，如在线、面对面或混合教学，青少年的生活被打乱了。我们和其他人曾就这些转变如何有助于延长睡眠时间、推迟睡眠时间和（更适合发育的）睡眠时间发表过评论。在此，我们将报告睡眠如何促进远程教学与更广泛的学业福祉（如认知功能、学校联系和压力）之间的联系：来自美国 50 个州的青少年（n = 4068）在 2020 年秋季完成了在线自我报告调查。教学方法从完全面对面教学到完全异步在线教育。睡眠参数包括睡眠时间和持续时间、睡眠障碍和睡眠相关损伤。感知到的学业幸福感定义为认知功能、与学校的联系以及与学校相关的压力。在不同的教学方法、它们之间的关联以及结构模型中，对睡眠和感知学业幸福感进行了研究：混合教学组和在线教学组的睡眠和学业幸福感有所不同。睡眠不稳定或睡眠紊乱较少与面对面教学有关，也与认知功能、学校联系和压力领域的积极结果有关。睡眠在很大程度上调节了因教学方法而产生的学业幸福感差异：这些数据强调了保护健康睡眠和面对面教学的必要性。适当的睡眠时间和持续时间、较少的睡眠障碍和与睡眠相关的损伤在很大程度上解释了远程教学与学习成绩之间的关系。虽然许多学生因 COVID-19 而 "失去了学习机会"，但这项研究也加入了更广泛的讨论，即确保适当的开学时间，以保证睡眠和学习成绩。

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引用次数: 0

Associations of prediabetes and sleep duration, and inflammation as a mediator in the China Health and Retirement Longitudinal Study 中国健康与退休纵向研究》中糖尿病前期与睡眠时间的关系，以及炎症作为中介的作用。

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Sleep Health

Pub Date : 2024-08-01 DOI: 10.1016/j.sleh.2024.01.011

Objective

The objective of this study was to examine the relationship between sleep duration and prediabetes, as well as to evaluate the influence of inflammation in mediating this association.

Methods

A total of 4632 participants from the China Health and Retirement Longitudinal Study (CHARLS) were included in this study, comprising both baseline and 4-year follow-up data. The prospective relationship between sleep duration and the risk of prediabetes was examined using logistic regression models. We used multinomial logistic regression to evaluate the impact of prediabetes on sleep duration changes over follow-up, assessing the role of C-reactive protein in the association using mediation analysis.

Results

Participants with short sleep duration (<5 hours) had a higher risk of prediabetes (odds ratios = 1.381 [95% CI: 1.028-1.857]) compared to those with normal sleep durations (7-8 hours). However, excessive sleep durations ( $\geq$ 9 hours) did not show a statistically significant association with prediabetes risk. Moreover, individuals at least 60 years old who experienced short sleep durations exhibited a higher risk of prediabetes. Individuals with prediabetes were more likely to have shorter sleep duration than excessive sleep duration (relative risk ratios = 1.280 [95% CI: 1.059-1.547]). The mediation analysis revealed a mediating effect of C-reactive protein on the association between prediabetes and reduced sleep duration.

Conclusions

Short sleep duration was identified as a risk factor for the incidence of prediabetes. Conversely, prediabetes was found to contribute to shorter sleep duration rather than excessive sleep duration. Moreover, elevated levels of C-reactive protein may serve as a potential underlying mechanism that links prediabetes with shorter sleep.

研究目的本研究的目的是探讨睡眠时间与糖尿病前期之间的关系，并评估炎症在调解这种关系中的影响：方法：本研究纳入了中国健康与退休纵向研究（CHARLS）的4632名参与者，包括基线数据和4年随访数据。我们使用逻辑回归模型研究了睡眠时间与糖尿病前期风险之间的前瞻性关系。我们使用多项式逻辑回归评估了糖尿病前期对随访期间睡眠时间变化的影响，并使用中介分析评估了 C 反应蛋白在两者关系中的作用：结果：睡眠时间短的参与者（结论：睡眠时间短被认为是糖尿病前期的一个风险因素：睡眠时间短被认为是糖尿病前期发病率的一个风险因素。相反，糖尿病是睡眠时间过短而不是睡眠时间过长造成的。此外，C 反应蛋白水平的升高可能是糖尿病前期与睡眠时间短之间的潜在联系机制。

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引用次数: 0

Inequities in adolescent sleep health in Aotearoa New Zealand: Cross-sectional survey findings 新西兰奥特亚罗瓦青少年睡眠健康的不平等：横断面调查结果。

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Sleep Health

Pub Date : 2024-08-01 DOI: 10.1016/j.sleh.2024.05.007

Objectives

To investigate ethnic inequities in, and social determinants of, adolescent sleep health in Aotearoa New Zealand.

Methods

Analysis of self-report data from a cross-sectional survey of secondary school students (12- to 18-year-olds). Analyses included weighted prevalence estimates of good and poor sleep health stratified by ethnicity, and multivariable logistic regression models concurrently adjusted for ethnicity, school year, gender, rurality, neighborhood deprivation, school decile, housing deprivation, sleeping elsewhere due to lack of adequate housing, unsafe environment, and racism.

Results

Inequities in social determinants of health were evident for Māori (Indigenous peoples of Aotearoa New Zealand; n = 1528) and minoritized (Pacific n = 1204; Asian n = 1927; Middle Eastern, Latin American, and African [MELAA] n = 210; and ‘Other' ethnicity n = 225) adolescents. A greater proportion of Māori, Pacific, Asian, MELAA, and ‘Other' adolescents had short sleep, compared to European (n = 3070). Māori, Pacific, Asian, and MELAA adolescents were more likely to report late bedtimes (after midnight), and Māori, Pacific, and ‘Other' adolescents were more likely to report early waketimes (5 AM-6 AM or earlier), on school days. Rurality, neighborhood deprivation, school-level deprivation, housing deprivation, sleeping elsewhere due to inadequate housing, unsafe environments, and racism partially, but not fully, explained associations between ethnicity and short sleep, late bedtimes, and early waketimes.

Conclusions

Ethnic inequities exist in adolescent sleep health in Aotearoa New Zealand. Socio-political actions are needed to address racism and colonialism as root causes of ethnic inequities in adolescent sleep, to ensure all young people are afforded the basic human right of good sleep health and associated mental and physical well-being.

目标：调查新西兰奥特亚罗瓦地区青少年睡眠健康的种族不平等和社会决定因素：调查新西兰奥特亚罗瓦地区青少年睡眠健康方面的种族不平等和社会决定因素：对中学生（12-18 岁）横断面调查的自我报告数据进行分析。分析包括按种族分层的睡眠健康良好和睡眠健康不良的加权流行率估计值，以及同时调整种族、学年、性别、乡村、邻里贫困、学校十分位数、住房贫困、因缺乏适当住房而睡在别处、不安全环境和种族主义的多变量逻辑回归模型：毛利人（新西兰奥特亚罗瓦土著居民；n = 1528）和少数民族（太平洋裔 n = 1204；亚裔 n = 1927；中东、拉美和非洲裔 [MELAA] n = 210；"其他 "族裔 n = 225）青少年在健康的社会决定因素方面存在明显的不平等。与欧裔青少年（n = 3070）相比，毛利青少年、太平洋裔青少年、亚裔青少年、中东、拉美和非洲裔青少年以及 "其他 "青少年睡眠时间较短的比例更高。毛利青少年、太平洋裔青少年、亚裔青少年和拉丁美洲及加勒比海地区青少年更有可能在上学日晚睡（午夜之后），而毛利青少年、太平洋裔青少年和 "其他 "青少年更有可能在上学日早醒（早上5点至6点或更早）。乡村、社区贫困、学校贫困、住房贫困、因住房不足而在其他地方睡觉、不安全的环境以及种族主义可以部分解释（但不能完全解释）种族与睡眠时间短、晚睡和早醒之间的关系：结论：在新西兰奥特亚罗瓦，青少年睡眠健康方面存在种族不平等。需要采取社会政治行动，解决导致青少年睡眠不平等的种族根源--种族主义和殖民主义问题，以确保所有青少年都能享有良好的睡眠健康及相关身心健康的基本人权。

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引用次数: 0

Heterogeneities in sleep duration and quality among U.S. immigrants from different racial and ethnic backgrounds 来自不同种族和民族背景的美国移民在睡眠时间和质量方面的异质性。

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Sleep Health

Pub Date : 2024-08-01 DOI: 10.1016/j.sleh.2024.03.006

Objectives

Sleep plays an essential role in well-being. Although U.S. immigrants are considerably growing, few studies have examined sleep in this diverse population, particularly those from Asian backgrounds. It is also unclear how sleep differs by the length of residence across immigrant groups. In this study, we examined the relationships among race/ethnicity, length of residence, and sleep using a nationally representative cohort of U.S. immigrants.

Methods

We analyzed data from the 2013-2018 National Health Interview Survey. The sample (N = 27,761; 14% ≥65 years old) included foreign-born adults from the following racial/ethnic backgrounds: non-Hispanic White, non-Hispanic Black, Asian (Chinese, Filipino, Asian Indian), and Hispanic/Latino. Length of residence was categorized as <5, 5-9, 10-14, and ≥15 years. Sleep was assessed with self-reported sleep duration (normal, short, and long) and poor sleep quality (trouble falling asleep, trouble staying asleep, and waking up unrested).

Results

Filipino and Hispanic/Latino immigrants reported the highest prevalence of short (41.8%) and long (7.0%) sleep, respectively. Non-Hispanic White immigrants had the highest prevalence rate across all three poor sleep quality measures (range 17.7-41.5%). Length of residence ≥15 years was significantly associated with worse sleep, and it moderated White-Asian differences in sleep quality. Immigrants from different racial/ethnic groups showed variations in sleep patterns as they resided longer in the US.

Conclusions

Immigrants exhibited substantial heterogeneities in sleep. Future research should investigate the contributing factors to the variations in their sleep patterns, both between groups and within the same group of immigrants, in order to inform tailored interventions.

目标睡眠对身心健康起着至关重要的作用。虽然美国移民人数大幅增长，但很少有研究对这一多样化人群，尤其是来自亚洲背景的移民的睡眠情况进行调查。此外，目前还不清楚不同移民群体的居住时间长短对睡眠有何影响。在这项研究中，我们利用具有全国代表性的美国移民队列研究了种族/族裔、居住时间和睡眠之间的关系：我们分析了 2013-2018 年全国健康访谈调查的数据。样本（N = 27,761; 14% ≥65岁）包括来自以下种族/族裔背景的外国出生成年人：非西班牙裔白人、非西班牙裔黑人、亚裔（中国人、菲律宾人、亚洲印第安人）和西班牙裔/拉丁美洲人。居住时间按结果分类：菲律宾裔移民和西班牙裔/拉丁美洲裔移民的睡眠时间最短（41.8%），睡眠时间最长（7.0%）。非西班牙裔白人移民在所有三项睡眠质量不良指标中的患病率最高（范围为 17.7%-41.5%）。居住时间≥15年与睡眠质量较差有显著相关性，而且它能调节白人与亚洲人在睡眠质量上的差异。来自不同种族/族裔群体的移民在美国居住时间越长，睡眠模式越不同：结论：移民在睡眠方面表现出很大的异质性。未来的研究应调查造成移民睡眠模式差异的因素，包括不同群体之间和同一移民群体内部的差异，以便为有针对性的干预措施提供信息。

{"title":"Heterogeneities in sleep duration and quality among U.S. immigrants from different racial and ethnic backgrounds","authors":"","doi":"10.1016/j.sleh.2024.03.006","DOIUrl":"10.1016/j.sleh.2024.03.006","url":null,"abstract":"<div><h3>Objectives</h3><p>Sleep plays an essential role in well-being. Although U.S. immigrants are considerably growing, few studies have examined sleep in this diverse population, particularly those from Asian backgrounds. It is also unclear how sleep differs by the length of residence across immigrant groups. In this study, we examined the relationships among race/ethnicity, length of residence, and sleep using a nationally representative cohort of U.S. immigrants.</p></div><div><h3>Methods</h3><p>We analyzed data from the 2013-2018 National Health Interview Survey. The sample (N = 27,761; 14% ≥65 years old) included foreign-born adults from the following racial/ethnic backgrounds: non-Hispanic White, non-Hispanic Black, Asian (Chinese, Filipino, Asian Indian), and Hispanic/Latino. Length of residence was categorized as <5, 5-9, 10-14, and ≥15years. Sleep was assessed with self-reported sleep duration (normal, short, and long) and poor sleep quality (trouble falling asleep, trouble staying asleep, and waking up unrested).</p></div><div><h3>Results</h3><p>Filipino and Hispanic/Latino immigrants reported the highest prevalence of short (41.8%) and long (7.0%) sleep, respectively. Non-Hispanic White immigrants had the highest prevalence rate across all three poor sleep quality measures (range 17.7-41.5%). Length of residence ≥15years was significantly associated with worse sleep, and it moderated White-Asian differences in sleep quality. Immigrants from different racial/ethnic groups showed variations in sleep patterns as they resided longer in the US.</p></div><div><h3>Conclusions</h3><p>Immigrants exhibited substantial heterogeneities in sleep. Future research should investigate the contributing factors to the variations in their sleep patterns, both between groups and within the same group of immigrants, in order to inform tailored interventions.</p></div>","PeriodicalId":48545,"journal":{"name":"Sleep Health","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disparities in sleep duration and quality by industry of employment and occupational class among Native Hawaiian/Pacific Islanders and non-Hispanic Whites in the United States 美国夏威夷原住民/太平洋岛民和非西班牙裔白人在睡眠时间和睡眠质量方面的差异（按就业行业和职业等级划分）。

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Sleep Health

Pub Date : 2024-08-01 DOI: 10.1016/j.sleh.2024.05.006

Objective

To investigate disparities in the work-sleep relationship between Native Hawaiian/Pacific Islanders (NHPIs) and non-Hispanic (NH)-White populations.

Methods

Using data from a nationally representative sample of U.S. adults (n = 20,828) in the 2014 National Health Interview Survey, we estimated prevalence of short sleep duration (<7 hours) among NHPIs (10%) and NH-Whites for each of 7 employment industry categories and 3 occupational classes. Mean age was 41 ± 0.5 years for NHPIs and 49 ± 0.2 years for NH-Whites. Women comprised 52% of both groups.

Results

NHPIs were more likely than NH-Whites to report short sleep duration across all industry of employment categories (except for food and accommodation services) and occupational classes. The disparity was widest among NHPI and NH-White workers in the “professional/management" industry category, with NHPIs having higher prevalence of very short (<6 hours; 20% vs. 7%) and short sleep (30% vs. 22%) durations and lower prevalence of recommended sleep duration (45% vs. 68%) and waking up feeling rested (53% vs. 67%). Among the occupational classes, the NHPI-White disparity was widest among participants who held support service occupations. Although professionals had the lowest and laborers had the highest prevalence of short sleep among the three occupational classes in both NHPI and NH-White groups, short sleep duration prevalence was higher among NHPI professionals (35%) than NH-White laborers (33%). NH-White workers across industry and occupational classes had higher sleep medication use prevalence compared to NHPI workers.

Conclusions

The work environment via occupation type may contribute to racial/ethnic disparities in short sleep. Further investigations are warranted.

目的调查夏威夷原住民/太平洋岛民（NHPIs）与非西班牙裔（NH）白人之间工作与睡眠关系的差异：利用 2014 年全国健康访谈调查中具有全国代表性的美国成年人样本（n = 20828）的数据，我们估算了睡眠时间短的流行率（结果：夏威夷原住民比非夏威夷原住民更容易出现睡眠时间短的情况：在所有行业的就业类别（食品和住宿服务除外）和职业类别中，国家高收入人群比国家高收入白人更有可能报告睡眠时间短。在 "专业/管理 "行业类别中，国家高危人群和国家高危人群-白人之间的差距最大，国家高危人群睡眠时间极短的发生率更高（结论：工作环境和职业类型可能会导致种族/族裔睡眠时间短的差异。有必要进行进一步调查。

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引用次数: 0

Sleep Health Times NSF 睡眠健康时报》NSF

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Sleep Health

Pub Date : 2024-08-01 DOI: 10.1016/S2352-7218(24)00155-4

引用次数: 0

Disadvantaged social status contributed to sleep disorders: An observational and genome-wide gene-environment interaction analysis 弱势社会地位导致睡眠障碍：一项观察性和全基因组的基因-环境交互作用分析。

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Sleep Health

Pub Date : 2024-08-01 DOI: 10.1016/j.sleh.2024.03.003

Background

Sleep is a natural and essential physiological need for individuals. Our study aimed to research the associations between accumulated social risks and sleep disorders.

Methods

In this study, we came up with a polysocial risk score (PsRS), which is a cumulative social risk index composed of 13 social determinants of health. This research includes 239,165 individuals with sleep disorders and social determinants of health data from the UK Biobank cohort. First, logistic regression models were performed to examine the associations of social determinants of health and sleep disorders, including chronotype, narcolepsy, insomnia, snoring, short and long sleep duration. Then, PsRS was calculated based on statistically significant social determinants of health for each sleep disorder. Third, a genome-wide gene-environment interaction study was conducted to explore the interactions between single-nucleotide polymorphisms and PsRS in relation to sleep disorders.

Results

Higher PsRS scores were associated with worse sleep status, with the adjusted odds ratio (OR) ranging from 1.10 (95% Confidence interval [CI]: 1.09-1.11) to 1.29 (95% CI: 1.27-1.30) for sleep disorders. Emotional stress (OR = 1.36, 95% CI: 1.28-1.43) and not in paid employment (OR = 2.62, 95% CI: 2.51-2.74) were found to have significant contributions for sleep disorders. Moreover, multiple single-nucleotide polymorphisms were discovered to have interactions with PsRS, such as FRAS1 (P = 2.57 × 10⁻¹⁴) and CACNA1A (P = 8.62 × 10⁻¹⁴) for narcolepsy, and ACKR3 (P = 1.24 × 10⁻⁸) for long sleep.

Conclusions

Our findings suggested that cumulative social risks was associated with sleep disorders, while the interactions between genetic susceptibility and disadvantaged social status are risk factors for the development of sleep disorders.

背景介绍睡眠是人的自然生理需求。我们的研究旨在探讨累积的社会风险与睡眠障碍之间的关联：在这项研究中，我们提出了一个多社会风险评分（PsRS），这是一个由 13 个健康的社会决定因素组成的累积性社会风险指数。这项研究包括英国生物库队列中的 239,165 名睡眠障碍患者和健康社会决定因素数据。首先，通过逻辑回归模型来研究健康的社会决定因素与睡眠障碍的关联，包括慢性型、嗜睡症、失眠、打鼾、睡眠时间短和睡眠时间长。然后，根据对每种睡眠障碍具有统计学意义的健康社会决定因素计算出 PsRS。第三，进行了一项全基因组基因-环境交互作用研究，以探讨单核苷酸多态性与睡眠障碍相关的PsRS之间的交互作用：PsRS得分越高，睡眠状况越差，调整后的睡眠障碍几率比（OR）从1.10（95% 置信区间[CI]：1.09-1.11）到1.29（95% 置信区间：1.27-1.30）不等。研究发现，情绪压力（OR = 1.36，95% CI：1.28-1.43）和未从事有偿工作（OR = 2.62，95% CI：2.51-2.74）对睡眠障碍有显著影响。此外，还发现多个单核苷酸多态性与 PsRS 有相互作用，如 FRAS1（P = 2.57 × 10-14）和 CACNA1A（P = 8.62 × 10-14）与嗜睡症有关，ACKR3（P = 1.24 × 10-8）与长睡眠有关：我们的研究结果表明，累积的社会风险与睡眠障碍有关，而遗传易感性和弱势社会地位之间的相互作用是睡眠障碍发生的风险因素。

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引用次数: 0

Sleep duration, napping behaviors and restless legs syndrome during pregnancy and the trajectories of ultrasonographic measures of fetal growth: Findings from the NICHD Fetal Growth Studies–Singletons 孕期睡眠时间、午睡行为和不安腿综合征与胎儿生长的超声波测量轨迹：NICHD胎儿生长研究-Singletons的发现。

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Sleep Health

Pub Date : 2024-08-01 DOI: 10.1016/j.sleh.2024.04.004

Objectives

Given the plausible mechanisms and the lacking of empirical evidence, the study aims to investigate how gestational sleep behaviors and the development of sleep disorders, such as restless legs syndrome, influence ultrasonographic measures of fetal growth.

Methods

The study included 2457 pregnant women from the NICHD Fetal Growth Studies - Singletons (2009-2013), who were recruited between 8-13 gestational weeks and followed up to five times during pregnancy. Women were categorized into six groups based on their total sleep hours and napping frequency. The trajectory of estimated fetal weight from 10-40 weeks was derived from three ultrasonographic measures. Linear mixed effect models were applied to model the estimated fetal weight in relation to self-reported sleep-napping behaviors and restless legs syndrome status, adjusting for age, race and ethnicity, education, parity, prepregnancy body mass index category, infant sex, and prepregnancy sleep-napping behavior.

Results

From enrollment to near delivery, pregnant women’s total sleep duration and nap frequency declined and restless legs syndrome symptoms frequency increased generally. No significant differences in estimated fetal weight were observed by sleep-napping group or by restless legs syndrome status. Results remained similar in sensitivity analyses and stratified analyses by women’s prepregnancy body mass index category (normal vs. overweight/obese) or by infant sex.

Conclusions

Our data indicate that there is no association between sleep during pregnancy—assessed as total sleep duration and napping frequency, nor restless legs syndrome symptoms—and fetal growth from weeks 10 to 40 in healthy pregnant women.

研究目的本研究旨在探讨妊娠期睡眠行为和睡眠障碍（如不安腿综合征）的发展如何影响胎儿生长的超声测量：该研究纳入了美国国家卫生与健康研究所（NICHD）胎儿生长研究--单胎（2009-2013年）中的2457名孕妇，她们在妊娠8-13周时被招募，并在妊娠期间接受了长达5次的随访。研究人员根据孕妇的总睡眠时间和午睡频率将其分为六组。10-40周期间的胎儿估计体重轨迹是通过三种超声波测量得出的。线性混合效应模型用于模拟估计胎儿体重与自我报告的睡眠打盹行为和不安腿综合征状态之间的关系，并对年龄、种族和民族、教育程度、奇偶数、孕前体重指数类别、婴儿性别和孕前睡眠打盹行为进行了调整：结果：从入学到临近分娩，孕妇的总睡眠时间和午睡次数均有所减少，不安腿综合征症状的出现频率普遍增加。在估计胎儿体重方面，睡眠中断组和不安腿综合征症状组没有发现明显差异。在敏感性分析和按妇女孕前体重指数类别（正常与超重/肥胖）或婴儿性别进行的分层分析中，结果仍然相似：我们的数据表明，在健康孕妇中，孕期睡眠（评估为总睡眠时间和小睡频率）或不安腿综合征症状与第10周至第40周的胎儿生长之间没有关联。

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引用次数: 0

Cover 2: Editorial Board 封面 2：编辑委员会

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Sleep Health

Pub Date : 2024-08-01 DOI: 10.1016/S2352-7218(24)00137-2

引用次数: 0