Sleep Health最新文献

{"title":"Sleep: Balancing reason with the subconscious","authors":"Pia B. Edwards, Meir Kryger MD","doi":"10.1016/j.sleh.2024.02.003","DOIUrl":"10.1016/j.sleh.2024.02.003","url":null,"abstract":"","PeriodicalId":48545,"journal":{"name":"Sleep Health","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Board page","authors":"","doi":"10.1016/S2352-7218(24)00086-X","DOIUrl":"https://doi.org/10.1016/S2352-7218(24)00086-X","url":null,"abstract":"","PeriodicalId":48545,"journal":{"name":"Sleep Health","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S235272182400086X/pdfft?md5=9bae2f7d5e61171c29cadcdc20886852&pid=1-s2.0-S235272182400086X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140638358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of insufficient sleep and adequate sleep on cognitive function in healthy adults","authors":"Molly E. Zimmerman PhD ,&nbsp;Giada Benasi PhD ,&nbsp;Christiane Hale MS ,&nbsp;Lok-Kin Yeung PhD ,&nbsp;Justin Cochran BS ,&nbsp;Adam M. Brickman PhD ,&nbsp;Marie-Pierre St-Onge PhD","doi":"10.1016/j.sleh.2023.11.011","DOIUrl":"10.1016/j.sleh.2023.11.011","url":null,"abstract":"<div><h3>Study objectives</h3><p>Although sleep affects a range of waking behaviors, the majority of studies have focused on sleep loss with relatively little attention on sustained periods of adequate sleep. The goal of this study was to use an experimental design to examine the effect of both of these sleep patterns on cognitive performance in healthy adults.</p></div><div><h3>Methods</h3><p>This study used a randomized crossover design. Participants who regularly slept 7-9 hours/night completed two 6-week intervention conditions, adequate sleep (maintenance of habitual bed/wake times) and insufficient sleep (reduction in sleep of 1.5 hours relative to adequate sleep), separated by a 2-6<!--> <!-->weeks (median<!--> <!-->=<!--> <!-->43<!--> <!-->days) washout period. Cognitive functioning was evaluated at baseline and endpoint of each intervention using the NIH Toolbox Cognition Battery. General linear models contrasted scores following each condition to the baseline of the first condition; the baseline of the second condition was included to evaluate practice effects.</p></div><div><h3>Results</h3><p>Sixty-five participants (age 35.9 ± 4.9<!--> <span>years, 89% women, 52% non-White race/ethnicity) completed study procedures. There was improvement in performance on the List Sorting Working Memory task after the adequate sleep condition that exceeded practice effects. Cognitive performance after insufficient sleep did not reach the level expected with practice and did not differ from baseline. A similar pattern was found on the Flanker Inhibitory Control and Attention task.</span></p></div><div><h3>Conclusions</h3><p>These findings contribute to our understanding of the complex interplay between sleep and cognition and demonstrate that consistent, stable sleep of at least 7 hours/night improves working memory and response inhibition in healthy adults.</p></div><div><h3>Clinical Trial Registration</h3><p>The manuscript reports on data from two clinical trials: Impact of Sleep Restriction on Performance in Adults (URL: https://clinicaltrials.gov/ct2/show/NCT02960776, ID Number: NCT02960776) and Impact of Sleep Restriction in Women (URL: https://clinicaltrials.gov/ct2/show/NCT02835261, ID Number: NCT02835261).</p></div>","PeriodicalId":48545,"journal":{"name":"Sleep Health","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139486331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early nap cessation in young children as a correlate of language and psychosocial outcomes: Evidence from a large Canadian sample","authors":"Adam T. Newton PhD ,&nbsp;Paul F. Tremblay PhD ,&nbsp;Laura J. Batterink PhD ,&nbsp;Graham J. Reid PhD","doi":"10.1016/j.sleh.2023.11.010","DOIUrl":"10.1016/j.sleh.2023.11.010","url":null,"abstract":"<div><h3>Objectives</h3><p>Most children stop napping between 2 and 5<!--> <!-->years old. We tested the association of early nap cessation (ie, children who stopped before their third birthday) and language, cognition functioning and psychosocial outcomes.</p></div><div><h3>Methods</h3><p><span>Data were from a national, longitudinal sample of Canadian children, with three timepoints. Children were 0-to-1 year old at T1, 2-to-3 years old at T2, and 4-to-5 years old at T3. Early nap cessation was tested as a correlate of children’s psychosocial functioning (cross-sectionally and longitudinally), cognitive function (longitudinally), and language skills (longitudinally). There were 4923 children (50.9% male; 90.0% White) and their parents in this study who were included in the main analyses. Parents reported on demographics, perinatal and developmental variables, child functioning, and child sleep. Children completed direct assessments of receptive language and cognitive ability. Nap cessation, demographic, and developmental-control variables were tested as correlates of cross-sectional and longitudinal outcomes using </span>linear regression (with a model-building approach).</p></div><div><h3>Results</h3><p>Early nap cessation correlated with higher receptive language ability (β = 0.059 ± 0.028) and lower anxiety (β = −<!--> <!-->0.039 ± 0.028) at T3, after controlling for known correlates of nap cessation, nighttime sleep, and other sociodemographic correlates of the outcomes. Cognitive ability, hyperactivity-inattention, and aggression were not correlated with nap cessation.</p></div><div><h3>Conclusions</h3><p>Early nap cessation is related to specific benefits (ie, better receptive language and lower anxiety symptoms). These findings align with previous research. Future research should investigate differences associated with late nap cessation and in nap-encouraging cultures, and by ethnicity.</p></div>","PeriodicalId":48545,"journal":{"name":"Sleep Health","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138812699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consumer preferences for sleep-tracking wearables: The role of scientific evaluation and endorsement","authors":"Lindsay P. Schwartz PhD ,&nbsp;Jaime K. Devine PhD ,&nbsp;Jake Choynowski BS ,&nbsp;Steven R. Hursh PhD","doi":"10.1016/j.sleh.2023.11.009","DOIUrl":"10.1016/j.sleh.2023.11.009","url":null,"abstract":"<div><h3>Objectives</h3><p>Accuracy and relevance to health outcomes are important to researchers and clinicians who use consumer sleep technologies, but economic demand motivates consumer sleep technology design. This report quantifies the value of scientific relevance to the general consumer in a dollar amount to convey the importance of device accuracy in terms that consumer sleep technology manufacturers can appreciate.</p></div><div><h3>Methods</h3><p>Survey data were collected from 368 participants on Amazon mTurk. Participants ranked sleep metrics, evaluation methods, and scientific endorsement by perceived level of importance. Participants indicated their likelihood of purchasing a hypothetical consumer sleep technology that had either (1) not been evaluated or endorsed; (2) had been evaluated but not endorsed, and; (3) had been evaluated and endorsed by a sleep science authority. Demand curves determined the relative value of each consumer sleep technology.</p></div><div><h3>Results</h3><p>Devices that were evaluated and endorsed had the most value, followed by those only evaluated, and then those with no evaluation. The unit price at which there was 50% probability of purchase increased by $30 or $48 for evaluation or endorsement, respectively, relative to a nonvalidated device. Respondents indicated the most valuable sleep metric was sleep duration, the most important evaluation method was against laboratory/hospital standards for sleep, and that the highest value of endorsement came from a medical institution.</p></div><div><h3>Conclusions</h3><p>Consumer demand is greatest for a device that has been evaluated by an independent laboratory and is endorsed by a medical institution. Consumer sleep technology manufacturers may be able to increase sales by partnering with sleep science authorities to produce a scientifically superior device.</p></div>","PeriodicalId":48545,"journal":{"name":"Sleep Health","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139049610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors for achieving optimal sleep in healthy children: Exploring sleep patterns in a sleep extension trial","authors":"Barbara C. Galland PhD ,&nbsp;Jillian J. Haszard PhD ,&nbsp;Rosie Jackson MDiet ,&nbsp;Silke Morrison PhD ,&nbsp;Kim Meredith-Jones PhD ,&nbsp;Dawn E. Elder FRACP, PhD ,&nbsp;Dean Beebe PhD ,&nbsp;Rachael W. Taylor PhD","doi":"10.1016/j.sleh.2023.09.012","DOIUrl":"10.1016/j.sleh.2023.09.012","url":null,"abstract":"<div><h3>Study objectives</h3><p>Earlier bedtimes can help some children get more sleep, but we don’t know which children, or what features of their usual sleep patterns could predict success with this approach. Using data from a randomized crossover trial of sleep manipulation, we sought to determine this.</p></div><div><h3>Methods</h3><p>Participants were 99 children aged 8-12<!--> <!-->years (49.5% female) with no sleep disturbances. Sleep was measured by actigraphy at baseline and over a restriction or extension week (1 hour later or earlier bedtime respectively), randomly allocated and separated by a washout week. Data were compared between baseline (week 1) and extension weeks only (week 3 or 5), using linear or logistic regression analyses as appropriate, controlling for randomization order.</p></div><div><h3>Results</h3><p>One hour less total sleep time than average at baseline predicted 29.7 minutes (95% CI: 19.4, 40.1) of sleep gained and 3.45 (95% CI: 1.74, 6.81) times higher odds of successfully extending sleep by &gt;30 minutes. Per standardized variable, less total sleep time and a shorter sleep period time were the strongest predictors (significant odds ratios (ORs) of 2.51 and 2.28, respectively). Later sleep offset, more variability in sleep timing and lower sleep efficiency also predicted sleep gains. The sleep period time cut-point that optimized prediction of successful sleep gains was &lt;8 hours 28 minutes with 75% of children’s baseline sleep in that range.</p></div><div><h3>Conclusions</h3><p>Children with a baseline sleep period time &lt;8½ hours a night obtained the most sleep from earlier bedtimes maintained over a week, demonstrating experimentally the value of earlier bedtimes to improve sleep.</p></div><div><h3>Clinical Trials Registry</h3><p>Australian New Zealand Clinical Trial Registry, ACTRN12618001671257, <span>https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=367587&amp;isReview=true</span><svg><path></path></svg>.</p></div>","PeriodicalId":48545,"journal":{"name":"Sleep Health","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2352721823002334/pdfft?md5=19d2653fb2bc3c02111eb3f0aac488ca&pid=1-s2.0-S2352721823002334-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trajectories of sleep duration and quality and their association with mild cognitive impairment, frailty, and all-cause mortality","authors":"Aarón Salinas-Rodríguez MSc ,&nbsp;Betty Manrique-Espinoza PhD ,&nbsp;Karla Moreno-Tamayo PhD ,&nbsp;Selene Guerrero-Zúñiga MD","doi":"10.1016/j.sleh.2023.12.002","DOIUrl":"10.1016/j.sleh.2023.12.002","url":null,"abstract":"<div><h3>Objectives</h3><p>To identify longitudinal trajectories of sleep duration<span> and quality and estimate their association with mild cognitive impairment<span>, frailty, and all-cause mortality.</span></span></p></div><div><h3>Methods</h3><p>We used data from three waves (2009, 2014, 2017) of the WHO Study on Global Aging and Adult Health in Mexico. The sample consisted of 2722 adults aged 50 and over. Sleep duration and quality were assessed by self-report. Sleep trajectories were determined by applying growth mixture models. Mixed-effects logistic (mild cognitive impairment) and ordinal logistic (frailty), and Cox proportional hazards (all-cause mortality) models were fitted.</p></div><div><h3>Results</h3><p><span><span>Three classes for sleep duration (“optimal-stable,” “long-increasing,” and “short-decreasing”) and quality (“very good-increasing,” “very good-decreasing,” and “moderate/poor stable”) were identified. Compared to the optimal-stable group, the long-increasing trajectory had greater odds for </span>mild cognitive impairment (odds ratio</span> <!-->=<!--> <!-->1.68, 95% CI: 1.01-2.78) and frailty (odds ratio<!--> <!-->=<!--> <!-->1.66, 95% CI: 1.13-2.46), and higher risk for all-cause mortality (hazard ratio<!--> <!-->=<!--> <!-->1.91, 95% CI: 1.14-3.19); and the short-decreasing class had a higher probability of frailty (odds ratio<!--> <!-->=<!--> <!-->1.83, 95% CI: 1.26-2.64). Regarding the sleep quality, the moderate/poor stable trajectory had higher odds of frailty (odds ratio<!--> <!-->=<!--> <!-->1.71, 95% CI: 1.18-2.47) than very good-increasing group.</p></div><div><h3>Conclusions</h3><p>These results have important implications for clinical practice and public health policies<span><span>, given that the evaluation and treatment<span> of sleep disorders need more attention in primary care settings. Interventions to detect and treat sleep disorders should be integrated into clinical practice to prevent or delay the appearance of alterations in older adults' physical and cognitive function. Further research on sleep quality and duration is warranted to understand their contribution to </span></span>healthy aging.</span></p></div>","PeriodicalId":48545,"journal":{"name":"Sleep Health","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The associations between instructional approach, sleep characteristics and adolescent mental health: Lessons from the COVID-19 pandemic","authors":"Patricia Wong PhD ,&nbsp;Lisa J. Meltzer PhD ,&nbsp;David Barker PhD ,&nbsp;Sarah M. Honaker PhD ,&nbsp;Judith A. Owens MD, MPH ,&nbsp;Jared M. Saletin PhD ,&nbsp;Azizi Seixas PhD ,&nbsp;Kyla L. Wahlstrom PhD ,&nbsp;Amy R. Wolfson PhD ,&nbsp;Mary A. Carskadon PhD","doi":"10.1016/j.sleh.2023.11.013","DOIUrl":"10.1016/j.sleh.2023.11.013","url":null,"abstract":"<div><h3>Objectives</h3><p>To test whether adolescents’ mental health during the COVID-19 pandemic is associated with the combination of their instructional approach(es) and their sleep patterns.</p></div><div><h3>Design</h3><p>Cross-sectional.</p></div><div><h3>Setting</h3><p>Adolescents were recruited through social media outlets in October and November 2020 to complete an online survey.</p></div><div><h3>Participants</h3><p>Participants were 4442 geographically and racially diverse, community-dwelling students (grades 6-12, 51% female, 36% non-White, 87% high schoolers).</p></div><div><h3>Measurements</h3><p><span>Participants completed items from the PROMIS Pediatric Depressive Symptoms and Anxiety scales. Participants reported their instructional approach(es), bedtimes, and wake times for each day in the past week. Participants were categorized into five combined instructional approach groups. Average sleep opportunity was calculated as the average time between bedtime and waketime. </span>Social jetlag was calculated as the difference between the average sleep midpoint preceding non-scheduled and scheduled days.</p></div><div><h3>Results</h3><p><span>Emotional distress was elevated in this sample, with a large proportion of adolescents reporting moderate-severe (T-score ≥ 65) levels of depressive symptoms (49%) and anxiety (28%). There were significant differences between instructional approach groups, such that adolescents attending all schooldays in-person reported the lowest depressive symptom and anxiety T-scores (</span><em>P</em> &lt; .001, <em>η</em>_<em>p</em>² = .012), but also the shortest sleep opportunity (<em>P</em> &lt; .001, <em>η</em>_<em>p</em>² = .077) and greatest social jetlag (<em>P</em> &lt; .001, <em>η</em>_<em>p</em>² = .037) of all groups. Adolescents attending school in person, with sufficient sleep opportunity (≥8-9 hours/night) and limited social jetlag (&lt;2 hours) had significantly lower depressive (<em>η</em>_<em>p</em>² = .014) and anxiety (<em>η</em>_<em>p</em>² = .008) T-scores than other adolescents.</p></div><div><h3>Conclusions</h3><p>Prioritizing in-person education and promoting healthy sleep patterns (more sleep opportunity, more consistent sleep schedules) may help bolster adolescent mental health.</p></div>","PeriodicalId":48545,"journal":{"name":"Sleep Health","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep improvements following atopic dermatitis management in young children","authors":"Jodi A. Mindell PhD ,&nbsp;Erin S. Leichman PhD ,&nbsp;Amisha M. Parikh-Das PhD, MPH ,&nbsp;Christina Lee MS ,&nbsp;Joseph W. Aquilina MD","doi":"10.1016/j.sleh.2023.10.015","DOIUrl":"10.1016/j.sleh.2023.10.015","url":null,"abstract":"<div><h3>Objectives</h3><p><span>The purpose of this pilot study was to assess improvements in associated sleep and caregiver mood following treatment of </span>atopic dermatitis<span> in young children.</span></p></div><div><h3>Methods</h3><p>Participants included children (n = 23; <em>M</em>_age<span> = 22.0 months) and their caregivers. Topical management of atopic dermatitis was conducted for 2 weeks, with measures of skin, sleep (child, caregiver), and mood (caregiver) at baseline and day 14.</span></p></div><div><h3>Results</h3><p>Topical management resulted in significant improvements in child skin, with associated increases in sleep consolidation. There were similar improvements in caregiver nightwakings, with nighttime sleep duration improving by over an hour. Caregivers also reported more energy to engage with their family and feeling better rested.</p></div><div><h3>Conclusions</h3><p>Overall, topical management significantly improved atopic dermatitis. There were concomitant improvements in sleep outcomes for children and their caregivers, as well as caregiver mood. Daily management of atopic dermatitis may result in improvements in not just skin health but also sleep and family well-being.</p></div>","PeriodicalId":48545,"journal":{"name":"Sleep Health","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138812718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-reported sleep and physical function during and after hospitalization","authors":"Christine M. Willinger MD, MPH ,&nbsp;Kimberly J. Waddell PhD, MSCI ,&nbsp;Vineet Arora MD, MPP ,&nbsp;Mitesh S. Patel MD, MBA ,&nbsp;S. Ryan Greysen MD, MHS","doi":"10.1016/j.sleh.2023.12.001","DOIUrl":"10.1016/j.sleh.2023.12.001","url":null,"abstract":"<div><h3>Purpose</h3><p>Poor sleep is associated with morbidity and mortality in the community; however, the health impact of poor sleep during and after hospitalization is poorly characterized. Our purpose was to describe trends in patient-reported sleep and physical function during and after hospitalization and evaluate sleep as a predictor of function after discharge.</p></div><div><h3>Methods</h3><p>This is a secondary analysis of trial data with 232 adults followed for 3<!--> <span><span>months after hospital discharge. Main measures were patient-reported surveys on sleep (Pittsburgh Sleep Quality Index) and physical function (Katz </span>Activities of Daily Living<span><span>, Lawton Instrumental Activities of Daily Living, and </span>Nagi Mobility Scale) were collected during hospitalization and at 1, 5, 9, and 13</span></span> <!-->weeks postdischarge.</p></div><div><h3>Results</h3><p>Patient-reported sleep declined significantly during hospitalization and remained worse for 3<!--> <span>months postdischarge (median Pittsburgh Sleep Quality Index</span> <!-->=<!--> <!-->8 vs. 6, <em>p</em> &lt; .001). In parallel, mobility declined significantly from baseline and remained worse at each follow-up time (median Nagi score<!--> <!-->=<!--> <!-->2 vs. 0, <em>p</em><span> &lt; .001). Instrumental activities of daily living similarly decreased during and after hospitalization, but basic activities of daily living were unaffected. In adjusted time-series logistic regression<span> models, the odds of mobility impairment were 1.48 times higher for each 1-point increase in Pittsburgh Sleep Quality Index score over time (95% CI 1.27-1.71, </span></span><em>p</em> &lt; .001).</p></div><div><h3>Conclusions</h3><p>Patient-reported sleep worsened during hospitalization, did not improve significantly for 3<!--> <span>months after hospitalization, and poor sleep was a significant predictor of functional impairment over this time. Sleep dysfunction that begins with hospitalization may persist and prevent functional recovery after discharge.</span></p></div><div><h3>Trial registration</h3><p>The primary study was registered at ClinicalTrials.gov NCT03321279.</p></div>","PeriodicalId":48545,"journal":{"name":"Sleep Health","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139049611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}