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Vulnerability and non-adherence to treatment in cisgender women living with HIV/AIDS: a scoping review (2000-2024). 感染艾滋病毒/艾滋病的顺性妇女的脆弱性和不坚持治疗:范围审查(2000-2024)。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-02-11 DOI: 10.1186/s13690-026-01852-z
Denise Eliziana de Souza, Cleber Nascimento do Carmo, Simone Monteiro
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引用次数: 0
Long-term trends of laryngeal cancer incidence and mortality in China from 2004 to 2019 by region: age-period-cohort analysis and 15-years projections to 2034. 2004 - 2019年中国各地区喉癌发病率和死亡率的长期趋势:年龄期队列分析和到2034年的15年预测
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-02-11 DOI: 10.1186/s13690-026-01851-0
Hui Shen, Hao-Sen Li, Jia-Jun Wang, Yu Tian, Ya-Xi Suo, Long Xie
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引用次数: 0
Linkage of HIV treatment and population-based surveillance records in rural South Africa: the AHRI Unified Data Platform (AUDP). 南非农村艾滋病毒治疗和基于人口的监测记录的联系:AHRI统一数据平台(AUDP)。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-02-07 DOI: 10.1186/s13690-026-01849-8
Dickman Gareta, Evelyn Lauren, Khumbo Shumba, Cornelius Nattey, Matthew P Fox, Koleka Mlisana, Matthias Egger, Dorina Onoya, Kobus Herbst, Jacob Bor

Background: Integrating HIV clinical records with population-based surveillance data allows the study of health care seeking behaviours, access to care, and predictors of patient outcomes. We implemented a graph-based record linkage algorithm to deduplicate and link HIV clinical and population-based surveillance records in an HIV-endemic setting in rural South Africa.

Methods: We linked four data sources to create the Africa Health Research Institute (AHRI) Unified Data Platform: AHRI's Health and Demographic Surveillance System (HDSS), AHRI Clinic and Hospital Information System (AHRILink), National Health Laboratory Service (NHLS), and Three Integrated Electronic Registers (TIER.Net) HIV care and treatment records. HDSS data were collected between January 1, 2000, and July 31, 2024, through repeated household surveys of over 140,000 individuals. Clinical and laboratory data were obtained for one hospital and 17 clinics in Hlabisa, KwaZulu-Natal, covering the HDSS surveillance area. We implemented a probabilistic record linkage algorithm trained and validated on a subset of records with national identity numbers. We assessed linkage accuracy, computed descriptive statistics for the linked database, and estimated the HIV care cascade for this population.

Results: A total of 986,832 records were successfully linked across the four databases, achieving a sensitivity of 92.7% and a positive predictive value of 96.5% (F-score=0.95). The average number of records (standard deviation (SD)) in TIER.Net, HDSS, AHRILink and NHLS were 1.18 (0.44),1.05 (0.23),1.13 (0.40), and 5.21 (4.24), respectively. The linked data indicated that 12,293 HDSS resident adults (≥15 years) were living with HIV at some point during the 2022 and 2024 surveillance rounds. Of these, 10,622 (86.4%) had ever sought HIV care in the public sector, of whom 10,492 (98.8%) had ever started ART and 7,065 (66.5%) were currently on ART, of whom 6,301 (89.2%) were virally suppressed(viral load<200 copies/mL).

Conclusion: HIV care and population surveillance records from four data sources were deduplicated and linked with high accuracy, revealing persistent gaps in retention in care and viral suppression in an HIV-endemic region in rural South Africa. The AHRI Unified Data Platform offers the potential to deepen our understanding of HIV epidemiology in a well-described population and to improve services for HIV.

Trial registration: Not applicable.

背景:将艾滋病毒临床记录与基于人群的监测数据相结合,可以研究寻求医疗保健的行为、获得医疗保健的机会和患者预后的预测因素。我们实施了一种基于图形的记录链接算法,在南非农村艾滋病流行环境中,对艾滋病临床和基于人群的监测记录进行去重复和链接。方法:我们将四个数据源连接起来创建非洲卫生研究所(AHRI)统一数据平台:非洲卫生研究所的健康和人口监测系统(HDSS)、非洲卫生研究所诊所和医院信息系统(AHRILink)、国家卫生实验室服务(NHLS)和三个综合电子登记(TIER)。Net)艾滋病毒护理和治疗记录。HDSS数据收集于2000年1月1日至2024年7月31日,通过对超过14万人的重复家庭调查。获得了夸祖鲁-纳塔尔省Hlabisa的一家医院和17家诊所的临床和实验室数据,涵盖了艾滋病监测地区。我们实现了一个概率记录链接算法,该算法在具有国家身份号码的记录子集上进行了训练和验证。我们评估了链接的准确性,计算了链接数据库的描述性统计数据,并估计了该人群的HIV护理级联。结果:4个数据库共成功链接986,832条记录,灵敏度为92.7%,阳性预测值为96.5% (F-score=0.95)。TIER中平均记录数(标准差)。Net、HDSS、AHRILink、NHLS分别为1.18(0.44)、1.05(0.23)、1.13(0.40)、5.21(4.24)。相关数据显示,在2022年和2024年的监测期间,有12293名HDSS居民成年人(≥15岁)感染了艾滋病毒。其中,10,622人(86.4%)曾在公共部门寻求艾滋病毒治疗,其中10,492人(98.8%)曾开始抗逆转录病毒治疗,7,065人(66.5%)目前正在接受抗逆转录病毒治疗,其中6,301人(89.2%)病毒受到抑制(病毒载量)。结论:来自四个数据源的艾滋病毒治疗和人口监测记录被重复删除,并与高精度联系在一起,揭示了南非农村艾滋病毒流行地区在护理和病毒抑制方面的持续差距。AHRI统一数据平台有可能加深我们对艾滋病毒流行病学的了解,并改善艾滋病毒服务。试验注册:不适用。
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引用次数: 0
How water quality affects perceived risk of waterborne disease: evidence from Zapopan, Mexico. 水质如何影响水传播疾病的感知风险:来自墨西哥Zapopan的证据。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-02-06 DOI: 10.1186/s13690-026-01847-w
Alejandro Lome-Hurtado, Pia Berger, Hugo Briseno

Background: Access to safe and clean drinking water is a key determinant of public health and well-being. This study explores the relationship between perceived unpleasant odor of tap water (as a proxy of water quality) and perception of health risks from tap water, in low- and middle-income areas of Mexico, emphasizing the role of perceptions shaped by sensory indicators such as taste, color, and odor. The connection between perceived unpleasant odor of tap water and perceived risk warrants attention as a public health concern, given its potential to influence consumer behavior, risk exposure, and trust in health-related products and services.

Methods: The analysis draws on household survey data collected through face-to-face interviews in Zapopan, Jalisco, Mexico, in October 2018, complemented with a review of existing literature. Statistical regression models were executed to assess the association between perceived water quality and perceived health risk from drinking tap water.

Results: The analysis shows that households perceiving an unpleasant odor in tap water had 29% higher odds of identifying it as a health risk (OR = 1.29), controlling for socioeconomic and demographic conditions.

Conclusions: The findings underscore the need for public health interventions that address both actual and perceived water quality. Integrated water policies should prioritize equity, strengthen community trust, and incorporate engagement strategies to mitigate health risks linked to water insecurity.

背景:获得安全和清洁的饮用水是公共健康和福祉的关键决定因素。本研究探讨了墨西哥低收入和中等收入地区自来水令人不愉快的气味(作为水质的代表)与自来水健康风险感知之间的关系,强调了由味道、颜色和气味等感官指标形成的感知的作用。感知到的自来水难闻气味与感知到的风险之间的联系值得作为一个公共卫生问题予以关注,因为它有可能影响消费者行为、风险暴露以及对与健康相关的产品和服务的信任。方法:分析利用2018年10月在墨西哥哈利斯科州萨帕潘通过面对面访谈收集的住户调查数据,并对现有文献进行回顾。采用统计回归模型评估感知水质与饮用自来水感知健康风险之间的关系。结果:分析表明,在控制社会经济和人口条件的情况下,感受到自来水中令人不快的气味的家庭将其识别为健康风险的几率高出29% (OR = 1.29)。结论:研究结果强调需要采取公共卫生干预措施,解决实际和感知的水质问题。综合水政策应优先考虑公平,加强社区信任,并纳入参与战略,以减轻与水不安全有关的健康风险。
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引用次数: 0
Evaluating changes and predictors of intention to act on health in urban development: a single-arm pre-post mixed-methods study of the changing mindsets intervention. 评估城市发展中对健康采取行动意愿的变化和预测因素:一项关于改变思维方式干预的单臂前后混合方法研究
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-02-06 DOI: 10.1186/s13690-026-01843-0
Sophie L Turnbull, Martha Jordan, Rebecca J Linnett, Krista Bondy
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引用次数: 0
Changes in premature mortality burden due to lung cancer attributable to tobacco exposure in rural southwest China: three repeated cross-sectional studies from 2013 to 2025. 中国西南农村烟草暴露导致肺癌过早死亡负担的变化:2013 - 2025年三项重复横断面研究
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-02-04 DOI: 10.1186/s13690-026-01848-9
Guo-Hui Li, Qing-Rou Bao, Rui-Min Shi, Fan Gu, Guo-Yu Ma, Allison Rabkin Golden, Le Cai

Background: Tobacco exposure remains the leading preventable cause of lung cancer. However, long-term trends in tobacco-related lung cancer premature mortality have been insufficiently studied in rural China. This study aimed to determine premature mortality burden due to lung cancer attributable to smoking and secondhand smoke (SHS) exposure in rural southwest China from 2013 to 2025.

Methods: Years of life lost (YLL) per 1,000 and mortality rate per 100,000 due to lung cancer were calculated from medical death certificates, while smoking and SHS exposure data were collected from three waves of cross-sectional interviews conducted in 2013, 2019, and 2025 among individuals aged ≥ 35 years in rural China. The population attributable fraction (PAF) was used to derive mortality and YLL due to lung cancer attributable to tobacco exposure.

Results: From 2013 to 2025, prevalence of smoking increased in men (75.56% vs. 81.12%, P < 0.01) but declined in women (2.34% vs. 1.40%, P < 0.01), while prevalence of exposure to SHS decreased significantly both in men (34.66% vs. 20.57%, P < 0.01) and women (44.12% vs. 28.24%, P < 0.01). The mortality and YLL rate of lung cancer rose significantly from 11.67 to 38.34 per 100,000 population and from 1.77 to 4.92 per 1,000 population, respectively. These increasing rates were also observed in both sexes, with the largest relative increase occurring among men. The age-standardized mortality and YLL rate of lung cancer attributable to both smoking and exposure to SHS increased consistently in men and women over the study period. Further, smoking contributed much more to mortality and YLL due to lung cancer than exposure to SHS in men, while the difference in contributions among women was less pronounced.

Conclusions: The premature mortality burden due to lung cancer attributable to smoking and SHS exposure has increased substantially in rural southwest China over the twelve-year study period. Future lung cancer prevention and management efforts should prioritize reducing smoking in men as well as strengthening protections against SHS exposure in women and other non-smoking populations.

背景:烟草暴露仍然是肺癌的主要可预防原因。然而,中国农村地区与烟草相关的肺癌过早死亡的长期趋势尚未得到充分研究。本研究旨在确定2013 - 2025年中国西南农村吸烟和二手烟暴露导致的肺癌过早死亡负担。方法:根据医学死亡证明计算肺癌导致的每1000年生命损失年(YLL)和每10万死亡率,同时从2013年、2019年和2025年对中国农村年龄≥35岁的个体进行的三波横断面访谈中收集吸烟和SHS暴露数据。使用人口归因分数(PAF)计算烟草暴露导致肺癌的死亡率和YLL。结果:从2013年到2025年,男性吸烟率上升(75.56% vs. 81.12%)。结论:在12年的研究期间,中国西南农村地区吸烟和暴露于SHS导致的肺癌过早死亡负担大幅增加。未来的肺癌预防和管理工作应优先考虑减少男性吸烟,并加强对女性和其他非吸烟人群接触二手烟的保护。
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引用次数: 0
Smoking status and cessation duration in relation to the progression of cardio-renal-metabolic multimorbidity: a prospective cohort study from the UK Biobank. 吸烟状况和戒烟持续时间与心肾代谢多病进展相关:来自英国生物银行的一项前瞻性队列研究。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-02-03 DOI: 10.1186/s13690-026-01846-x
Xinhui Liu, Shuo Wu, Heng Zhang, Fuzhong Xue
<p><strong>Background: </strong>This study aimed to investigate the association of smoking status and years since cessation with the onset, progression, and prognosis of cardio-renal-metabolic (CRM) multimorbidity (CRMM).</p><p><strong>Methods: </strong>This study included participants from the UK Biobank who were free of CRM disease at baseline. Covariates adjusted Cox proportional hazards models were employed to evaluate the associations of smoking status and years since smoking cessation with the risks of individual CRM diseases, including ischemic heart disease (IHD), stroke, type 2 diabetes (T2D), and chronic kidney disease (CKD), as well as with each state in CRMM progression, including first CRM disease (FCRMD), CRMM (defined as the occurrence of two or more CRM diseases), and death. Multi-state models were used to analyze the associations between smoking-related behaviors and CRMM progression. The effects of smoking cessation were further explored within subgroups according to sex, age at smoking initiation, smoking duration, smoking intensity, and genetic risk scores for individual CRM diseases.</p><p><strong>Results: </strong>In total, 356,071 participants (median age 57 years; 44.9% male) who were free of CRM disease (healthy) at baseline and had complete information on smoking status were included. During a median follow-up of 13.6 years, 56,786 participants developed a FCRMD, and 11,508 progressed to CRMM, of whom 2,796 subsequently died. Across all transitions from healthy to FCRMD, then to CRMM, and ultimately to death, current smoking had a greater impact on transitions leading to mortality. Compared with never smokers, current smokers had an adjusted hazard ratio of 1.44 (95% CI: 1.40-1.47) for the transition from healthy to FCRMD and 2.49 (95% CI: 2.38-2.60) for the transition from healthy to death. Approximately 25 years of smoking cessation were required for risks across all transitions in CRMM progression among former smokers to became not significantly different from those of never smokers. Compared with current smokers, former smokers experienced significantly lower risks for transitions leading to death shortly after cessation, whereas risk reductions for the transitions from healthy to FCRMD and from FCRMD to CRMM were not observed until more than 5 and 20 years after cessation, respectively. When disease-specific transitions were further considered, longer post-cessation periods were required to achieve significant risk reductions for transitions from healthy to T2D or CKD and from IHD or T2D to death, compared with current smokers. The effects of smoking cessation on CRMM progression varied by sex and previous smoking behavior, but not by genetic susceptibility to specific CRM diseases.</p><p><strong>Conclusion: </strong>Smoking has substantial but varied impacts across transitions in CRMM progression and disease-specific pathways. Long-term smoking cessation is an important strategy for reducing the risk of CRMM onset
背景:本研究旨在探讨吸烟状况和戒烟年限与心肾代谢(CRM)多病(CRMM)的发病、进展和预后的关系。方法:本研究纳入了基线时无CRM疾病的英国生物银行参与者。采用协变量调整的Cox比例风险模型来评估吸烟状况和戒烟年限与个体CRM疾病风险的关系,包括缺血性心脏病(IHD)、中风、2型糖尿病(T2D)和慢性肾病(CKD),以及与CRMM进展的每个状态的关系,包括首次CRM疾病(FCRMD)、CRMM(定义为两种或两种以上CRM疾病的发生)和死亡。采用多状态模型分析吸烟相关行为与CRMM进展之间的关系。根据性别、开始吸烟年龄、吸烟持续时间、吸烟强度和个体CRM疾病的遗传风险评分,在亚组中进一步探讨戒烟的影响。结果:共有356,071名参与者(中位年龄57岁,44.9%为男性)在基线时无CRM疾病(健康),并有完整的吸烟状况信息。在中位13.6年的随访期间,56,786名参与者发展为FCRMD, 11,508名进展为CRMM,其中2,796名随后死亡。在从健康到FCRMD,然后到CRMM,最终到死亡的所有转变中,当前吸烟对导致死亡率的转变有更大的影响。与从不吸烟者相比,目前吸烟者从健康过渡到FCRMD的调整风险比为1.44 (95% CI: 1.40-1.47),从健康过渡到死亡的调整风险比为2.49 (95% CI: 2.38-2.60)。戒烟约25年后,前吸烟者与从不吸烟者之间的CRMM进展的所有转变的风险没有显著差异。与目前的吸烟者相比,曾经的吸烟者在戒烟后不久发生转变导致死亡的风险显著降低,而从健康到FCRMD和从FCRMD到CRMM的转变风险分别在戒烟后5年和20年以上才观察到。当进一步考虑特定疾病的转变时,与当前吸烟者相比,戒烟后需要更长的时间才能显著降低从健康转变为T2D或CKD以及从IHD或T2D转变为死亡的风险。戒烟对CRMM进展的影响因性别和既往吸烟行为而异,但不受特定CRM疾病的遗传易感性的影响。结论:吸烟在CRMM进展和疾病特异性途径的转变中具有实质性但不同的影响。长期戒烟是降低CRMM发病和进展风险的重要策略。有特定吸烟习惯的人(如男性或重度吸烟者)和处于某些过渡状态的人在戒烟后的短期内需要特别注意。
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引用次数: 0
India's digital-first approach to sickle cell disease elimination. 印度消除镰状细胞病的数字优先方法。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-02-02 DOI: 10.1186/s13690-025-01819-6
Akhil R Nair
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引用次数: 0
Implementation and evaluation of a peer-to-peer support program in oncology: study protocol for the PaRole Onco France model. 肿瘤学中点对点支持项目的实施和评估:法国假释Onco模型的研究方案。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-30 DOI: 10.1186/s13690-025-01827-6
Yaël Busnel, Marie-Pascale Pomey, Anne Termoz, Véronique Christophe, Christophe Tournigand, Emmanuelle Jouet, Laurie Panse, Stéphane Cognon, Claude Ganter, Alexandra Villate, Pauline Maisani, Marie Preau, Julie Haesebaert
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引用次数: 0
Mental health help-seeking behaviour among migrant workers and migrant domestic workers in Singapore: a mixed-methods study. 新加坡移徙工人和移徙家庭佣工的心理健康求助行为:一项混合方法研究。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-30 DOI: 10.1186/s13690-026-01844-z
Mythily Subramaniam, Yunjue Zhang, Pratika Satghare, Yen Sin Koh, Anitha Jeyagurunathan, Yun Ting Lee, S Archana, M Iskandar Shah, Jason Ch Yap, Chee Yong Lim, Lenny Azuree, Halina Talib, Siow Ann Chong
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引用次数: 0
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