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Effectiveness of a guided multicomponent internet and mobile gratitude training program - A pragmatic randomized controlled trial 指导性多成分互联网和移动感恩培训计划的效果--实用随机对照试验
IF 3.6 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-11-12 DOI: 10.1016/j.invent.2024.100787
Dirk Lehr , Henning Freund , Bernhard Sieland , Lina Kalon , Matthias Berking , Heleen Riper , David Daniel Ebert

Objective

To investigate the effectiveness of a guided, internet- and smartphone-based gratitude intervention on the transdiagnostic risk-factor ‘repetitive negative thinking’. The multicomponent intervention integrates a variety of gratitude exercises, targeting the cognitive, emotional and behavioural facets of gratitude.

Method

Two hundred adults with pronounced repetitive negative thinking were recruited from the general population. Participants were randomly assigned to either a four-session guided gratitude intervention (n = 100) or waiting list (n = 100). The primary outcome was repetitive negative thinking three months after randomization, with exploratory assessments at six weeks and six months, the latter just for participants in the intervention group.

Results

Following the intention-to-treat principle, by analyses of covariance (ANCOVA), the gratitude intervention group exhibited significantly lower levels of repetitive negative thinking than controls at three months, with d = 0.66, 95 % CI [0.37, 0.94] maintained at six-month follow-up. Significant and meaningful beneficial effects were observed in symptoms of depression (d = 0.42) and generalized anxiety (d = 0.38). These effects were notably stronger in intervention completers who finished at least three sessions.

Conclusions

Results suggest that a multicomponent gratitude intervention is effective at reducing repetitive negative thinking. Multicomponent interventions may be a next step needed to fully realize the potential of gratitude interventions. Such interventions could expand the repertoire of transdiagnostic interventions, especially for repetitive negative thinking. Furthermore, due to its positive connotations, gratitude is a candidate for an indirect intervention aimed at reducing the burden of depression in the general population.

Trial registration

The study is registered in the German Clinical Trial Register (approved primary register of the WHO) as DRKS00006825. The trial protocol can be assessed at: https://www.drks.de/
目的研究基于互联网和智能手机的指导性感恩干预对跨诊断风险因素 "重复性消极思维 "的效果。方法从普通人群中招募了 200 名有明显重复性消极思维的成年人。参与者被随机分配到为期四节的引导式感恩干预(100 人)或等待名单(100 人)中。结果根据意向治疗原则,通过协方差分析(ANCOVA),感恩干预组在三个月后的重复性消极思维水平明显低于对照组,在六个月的随访中,d = 0.66,95 % CI [0.37, 0.94]保持不变。在抑郁症状(d = 0.42)和广泛焦虑症状(d = 0.38)方面,观察到了显著而有意义的有益效果。结论结果表明,多成分感恩干预能有效减少重复性消极思维。多成分干预可能是充分发挥感恩干预潜力所需的下一步。这种干预可以扩大跨诊断干预的范围,尤其是针对重复性消极思维的干预。此外,由于其积极的内涵,感恩也是旨在减轻普通人群抑郁负担的间接干预措施的候选对象。试验注册该研究已在德国临床试验注册中心(世界卫生组织批准的一级注册中心)注册,注册号为 DRKS00006825。试验方案可在以下网址进行评估: https://www.drks.de/
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引用次数: 0
Psychotherapy 2.0 - Application context and effectiveness of sensor technology in psychotherapy with children and adolescents: A systematic review 心理治疗 2.0 - 传感器技术在儿童和青少年心理治疗中的应用环境和效果:系统回顾
IF 3.6 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-11-06 DOI: 10.1016/j.invent.2024.100785
Annika K. Alt , Anja Pascher , Lennart Seizer , Marlene von Fraunberg , Annette Conzelmann , Tobias J. Renner

Background

E-mental health applications have been increasingly used in the psychotherapeutic care of patients for several years. State-of-the-art sensor technology could be used to determine digital biomarkers for the diagnosis of mental disorders. Furthermore, by integrating sensors into treatment, relevant contextual information (e.g. field of gaze, stress levels) could be made transparent and improve the treatment of people with mental disorders. An overview of studies on this approach would be useful to provide information about the current status quo.

Methods

A systematic review of the use of sensor technology in psychotherapy for children and adolescents was conducted with the aim of investigating the use and effectiveness of sensory technology in psychotherapy treatment. Five databases were searched for studies ranging from 2000 to 2023. The study was registered by PROSPERO (CRD42023374219), conducted according to Cochrane recommendations and used the PRISMA reporting guideline.

Results

Of the 38.560 hits in the search, only 10 publications met the inclusion criteria, including 3 RCTs and 7 pilot studies with a total of 257 subjects. The study population consisted of children and adolescents aged 6 to 19 years with mental disorders such as OCD, anxiety disorders, PTSD, anorexia nervosa and autistic behavior. The psychotherapy methods investigated were mostly cognitive behavioral therapy (face-to-face contact) with the treatment method of exposure for various disorders. In most cases, ECG, EDA, eye-tracking and movement sensors were used to measure vital parameters. The heterogeneous studies illustrate a variety of potential useful applications of sensor technology in psychotherapy for adolescents. In some studies, the sensors are implemented in a feasible approach to treatment.

Conclusion

Sensors might enrich psychotherapy in different application contexts.
However, so far there is still a lack of further randomized controlled clinical studies that provide reliable findings on the effectiveness of sensory therapy in psychotherapy for children and adolescents. This could stimulate the embedding of such technologies into psychotherapeutic process.
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023374219, identifier [CRD42023374219].
背景几年来,电子心理健康应用越来越多地用于病人的心理治疗。最先进的传感器技术可用于确定诊断精神障碍的数字生物标记。此外,通过将传感器整合到治疗中,相关的背景信息(如注视范围、压力水平)可以变得透明,从而改善对精神障碍患者的治疗。我们对传感器技术在儿童和青少年心理治疗中的应用进行了系统综述,旨在研究感知技术在心理治疗中的应用和效果。我们在五个数据库中搜索了 2000 年至 2023 年的研究。该研究已在 PROSPERO(CRD42023374219)注册,根据 Cochrane 建议进行,并采用了 PRISMA 报告指南。结果在 38.560 次检索中,只有 10 篇出版物符合纳入标准,其中包括 3 项 RCT 和 7 项试点研究,共有 257 名受试者。研究对象包括患有强迫症、焦虑症、创伤后应激障碍、神经性厌食症和自闭症等精神障碍的 6 至 19 岁儿童和青少年。所调查的心理治疗方法主要是认知行为疗法(面对面接触),以及针对各种障碍的暴露治疗方法。在大多数情况下,使用心电图、电子数据采集、眼动跟踪和运动传感器来测量生命参数。这些不同的研究说明了传感器技术在青少年心理治疗中的各种潜在有用应用。在一些研究中,传感器被应用于可行的治疗方法中。结论在不同的应用环境中,传感器可能会丰富心理治疗的内容。然而,迄今为止,仍然缺乏进一步的随机对照临床研究,以提供关于感官疗法在儿童和青少年心理治疗中的有效性的可靠结论。这可以促进将此类技术嵌入心理治疗过程。https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023374219,标识符[CRD42023374219]。
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引用次数: 0
Change processes in cognitive therapy for social anxiety disorder: A comparison of face-to-face and internet-based treatment formats 社交焦虑症认知疗法的改变过程:面对面治疗与网络治疗形式的比较
IF 3.6 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-11-02 DOI: 10.1016/j.invent.2024.100786
Graham R. Thew , Anke Ehlers , David M. Clark

Background

Compared to efficacy research, studies investigating the processes of change in psychological therapy are rare, especially for internet-based interventions. While many online therapies are based on face-to-face therapy protocols, it is unknown whether the processes of clinical improvement differ between these treatment formats.

Objective

To examine candidate change processes in an online therapist-guided cognitive therapy intervention for social anxiety disorder (iCT-SAD), and compare the results to the corresponding face-to-face therapy (CT-SAD).

Methods

Data from a randomised controlled trial (n = 99) were analysed using Multilevel Structural Equation Models, incorporating the temporal precedence of the process variable, and disaggregating the within- and between-subject components of the predictors. These examined three candidate change processes: self-focused attention, negative social cognitions, and depressed mood. Moderated mediation models provided an additional test of the moderating effect of treatment format.

Results

Negative social cognitions and self-focused attention were supported as significant mediators of clinical improvement in both CT-SAD and iCT-SAD. Effects were of similar strength and moderated mediation was not observed. There was also evidence of cyclical relationships between social anxiety symptoms and these process variables. Depressed mood also emerged as a significant but weak mediator in CT-SAD, but not in iCT-SAD. Moderated mediation was not observed.

Conclusion

The online format of therapy showed a similar pattern of change processes to face-to-face treatment, with self-focused attention and negative social cognitions mediating clinical improvement in both treatments. Efforts to improve the efficacy and efficiency of SAD interventions by targeting these factors may therefore be equally applicable to online and face-to-face interventions.
背景与疗效研究相比,调查心理治疗变化过程的研究很少见,尤其是基于互联网的干预。目的 研究社交焦虑症在线治疗师指导的认知疗法干预(iCT-SAD)的候选变化过程,并将结果与相应的面对面疗法(CT-SAD)进行比较。方法 使用多层次结构方程模型分析随机对照试验(n = 99)的数据,将过程变量的时间优先性纳入其中,并对预测因素的受试者内和受试者间成分进行分解。这些模型考察了三个候选变化过程:自我关注、消极社会认知和抑郁情绪。结果在 CT-SAD 和 iCT-SAD 中,负性社会认知和自我关注被认为是临床改善的重要中介因素。两者的效应强度相似,且未观察到调节中介效应。还有证据表明,社交焦虑症状与这些过程变量之间存在周期性关系。在 CT-SAD 中,抑郁情绪也是一个显著但微弱的中介因素,但在 iCT-SAD 中却不是。结论:在线治疗与面对面治疗显示出相似的变化过程模式,自我关注和消极社交认知对两种治疗方法的临床改善都有中介作用。因此,针对这些因素提高SAD干预疗效和效率的努力可能同样适用于在线和面对面干预。
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引用次数: 0
Are there unique facets of therapeutic alliance for users of digital mental health interventions? An examination with the eHealth Therapeutic Alliance Inventory 数字心理健康干预用户的治疗联盟是否有其独特之处?使用电子健康治疗联盟量表进行研究
IF 3.6 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-10-28 DOI: 10.1016/j.invent.2024.100783
Ohad Ashur, Chen R. Saar, Or Brandes, Amit Baumel
Therapeutic alliance (TA) is a well-established predictor of clinical outcomes in traditional psychotherapy. However, its association with outcomes in eHealth interventions has been inconsistent, which might be due to the absence of measurements specifically designed to capture TA in eHealth settings. The eHealth Therapeutic Alliance Inventory (ETAI) incorporates conventional as well as unique eHealth TA subscales, enabling to examine the contribution of new facets of TA beyond traditional concepts. This study investigates the predictive contribution of eHealth TA subscales compared to conventional TA subscales on clinical outcomes and evaluates the concurrent criterion validity of the ETAI. The study was conducted within the framework of a randomized controlled trial involving a 10-week digital parent training program aimed at addressing child disruptive behaviors. Parents were randomly assigned to either an enhanced-quality or a standard-quality program. Parents from 68 families completed the ETAI at five weeks' post-program initiation and at the post-intervention phase. The primary outcome was the improvement in child behavior, measured by the Eyberg Child Behavior Inventory. Positive Pearson correlations were found between all ETAI subscales covering unique eHealth TA aspects, measured at the 5-week time-point, and improvement in child behavior at post-intervention (rs ≥ 0.23, ps < 0.03). The conventional TA subscale showed no significant Pearson correlation with improvement in child behavior. When examining the unique contributions of ETAI-subscales to explain the improvement in child behavior, only ETAI-Perceived Emotional Investment subscale was found to have a unique contribution (β = 0.29, p = 0.019). In addition, scores on most ETAI subscales were significantly higher among parents using the enhanced-quality program compared with the standard program (Cohen's ds > 0.48), reinforcing ETAI's criterion validity. The development of TA scales that incorporates unique eHealth TA subscales show initial promise in predicting outcomes. Further research is needed to better understand how different factors of eHealth TA relate to clinical outcomes across diverse clinical targets and programs.
治疗联盟(TA)是传统心理疗法中预测临床疗效的一个行之有效的指标。然而,在电子健康干预中,治疗联盟与疗效之间的关系并不一致,这可能是由于缺乏专门用于捕捉电子健康环境中治疗联盟的测量指标。电子健康治疗联盟量表(ETAI)包含了传统的和独特的电子健康治疗联盟分量表,从而能够检验传统概念之外的新的治疗联盟方面的贡献。本研究调查了与传统 TA 子量表相比,电子健康 TA 子量表对临床结果的预测贡献,并评估了 ETAI 的并行标准有效性。这项研究是在随机对照试验框架内进行的,该试验涉及一项为期 10 周的数字家长培训计划,旨在解决儿童的干扰行为。家长们被随机分配到增强质量或标准质量的项目中。来自 68 个家庭的家长在项目启动后 5 周和干预后阶段完成了 ETAI。主要结果是儿童行为的改善,采用艾伯格儿童行为量表进行测量。在 5 周时间点测量的涵盖电子健康 TA 独特方面的所有 ETAI 分量表与干预后儿童行为改善之间均存在正的皮尔逊相关性(rs ≥ 0.23, ps < 0.03)。常规 TA 分量表与儿童行为的改善没有明显的皮尔逊相关性。在研究 ETAI 子量表对解释儿童行为改善的独特贡献时,发现只有 ETAI-感知情感投资子量表具有独特贡献(β = 0.29,P = 0.019)。此外,与标准项目相比,大多数 ETAI 子量表的得分在使用增强质量项目的家长中明显更高(Cohen's ds > 0.48),这加强了 ETAI 的标准效度。结合独特的电子健康 TA 子量表开发的 TA 量表在预测结果方面初见成效。要更好地了解电子健康 TA 的不同因素与不同临床目标和项目的临床结果之间的关系,还需要进一步的研究。
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引用次数: 0
Predictors of participant compliance with ecological momentary assessment among individuals with chronic pain who are using cannabis and opioids 使用大麻和阿片类药物的慢性疼痛患者接受生态瞬间评估的预测因素
IF 3.6 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-10-26 DOI: 10.1016/j.invent.2024.100784
Jungin Joo , Janardan Devkota , Bryant M. Stone , Kelly E. Dunn , Vadim Zipunnikov , Ryan Vandrey , Patrick H. Finan , Johannes Thrul

Background

Cannabis may be an alternative or adjunct to opioid therapy for chronic pain. However, there are limited data on patterns of opioid medication and medical cannabis use. The current study investigated the feasibility of using Ecological Momentary Assessment (EMA) to assess patterns of prescription opioids and medical cannabis among individuals experiencing chronic pain.

Method

The study included 133 participants recruited online. Participants were 42.6 (SD = 13.9) years old on average and the majority were men (57.9 %) and Non-Hispanic White (63.2 %). Participants completed a baseline assessment, followed by 30 days of EMA data collection with four randomly prompted past-hour surveys and one daily diary per day, and a follow-up survey that assessed perceived EMA burden. Simple and multivariable linear regression models were estimated to investigate participant predictors of the proportion of EMA surveys completed (past-hour surveys and daily diaries in separate models).

Results

Compliance rates for EMA prompts were 89.7 % for daily diaries and 63.3 % for past-hour surveys. In multivariable regression, participants holding a graduate degree completed a lower proportion of daily diaries (b = −0.109, SE = 0.052, p < .05) and past-hour surveys (b = −0.148, SE = 0.071, p < .05), compared to those with less than a 4-year degree. Participants completing a higher proportion of daily diaries reported greater ease of use at follow-up (b = 0.050, SE = 0.022, p < .05) and those completing a higher proportion of past-hour surveys desired higher rewards (b = 0.066, SE = 0.033, p < .05).

Conclusions

Study results confirm the feasibility of using EMA methods to assess patterns of prescription opioids and medical cannabis among individuals experiencing chronic pain.
背景大麻可以替代或辅助阿片类药物治疗慢性疼痛。然而,有关阿片类药物和医用大麻使用模式的数据十分有限。本研究调查了使用生态瞬间评估(EMA)评估慢性疼痛患者处方阿片类药物和医用大麻使用模式的可行性。参与者平均年龄为 42.6 岁(SD = 13.9),大多数为男性(57.9%)和非西班牙裔白人(63.2%)。参与者完成了基线评估,随后进行了为期 30 天的 EMA 数据收集,包括四次随机提示的过去小时调查和一次每日日记,以及一次评估 EMA 负担感知的后续调查。对简单和多变量线性回归模型进行了估算,以调查参与者完成 EMA 调查比例的预测因素(过去小时调查和每日日记在不同的模型中)。在多变量回归中,与拥有 4 年以下学位的参与者相比,拥有研究生学位的参与者完成每日日记(b = -0.109,SE = 0.052,p < .05)和过去小时调查(b = -0.148,SE = 0.071,p < .05)的比例较低。研究结果证实了使用 EMA 方法评估慢性疼痛患者处方阿片类药物和医用大麻使用模式的可行性。
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引用次数: 0
Evaluating the web-based ‘Partner in Balance’ program for informal caregivers of people with Huntington's disease: A pilot study 评估针对亨廷顿氏病患者非正式照顾者的网络 "平衡伙伴 "计划:试点研究
IF 3.6 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-10-21 DOI: 10.1016/j.invent.2024.100782
Maud M.J. Daemen , Lizzy M.M. Boots , Mayke Oosterloo , Marjolein E. de Vugt , Annelien A. Duits

Background

Huntington's disease (HD) poses significant challenges for both affected individuals and their informal caregivers. With the progression of HD, caregivers frequently prioritize caring for the person with HD over their own well-being. ‘Partner in Balance’ (PiB) is an 8-week online self-management program guided by a personal coach, developed to help caregivers of people with HD cope with challenging situations and develop skills to increase resilience and prevent overburdening.

Aims

This pilot study evaluates the feasibility and preliminary effects of the PiB-HD program.

Methods

The study employed a pre-post design. Perceived feasibility by HD caregivers was evaluated using both quantitative and qualitative measures. Preliminary effects were based on self-report measures of self-efficacy, mastery, mood, quality of life, and capability to function. Coaches' evaluations were conducted using a questionnaire.

Results

In total, 18 caregivers completed the intervention. Findings demonstrate positive responses regarding the program's usability, relevance, and acceptability. Participants found the program helpful in addressing challenges, gaining insight into their actions, and feeling better equipped with skills to face future challenges. Descriptive statistics suggest that the PiB-HD program shows potential for reducing stress and anxiety. Additionally, coaches (n = 9) viewed the program positively for its usability, integration potential into their work, flexibility, and time efficiency.

Conclusions

The PiB-HD program proved to be feasible, usable and acceptable for caregivers of people with HD. These results provide directions for further research into the effectiveness of PiB-HD, and can already be utilized to advise on the deployment of eHealth in the provision of HD care.
背景亨廷顿氏病(Huntington's disease,HD)给患者及其非正式护理人员都带来了巨大的挑战。随着亨廷顿舞蹈症病情的发展,照顾者往往会将照顾亨廷顿舞蹈症患者置于自己的福祉之上。平衡中的伙伴"(PiB)是一项为期 8 周的在线自我管理计划,由一名私人教练指导,旨在帮助 HD 患者的照顾者应对具有挑战性的情况,并培养他们提高适应能力和防止负担过重的技能。采用定量和定性的方法评估血液透析护理人员认为的可行性。初步效果基于对自我效能、掌握程度、情绪、生活质量和功能能力的自我报告测量。结果共有 18 名护理人员完成了干预。结果表明,该计划的可用性、相关性和可接受性都得到了积极的回应。参与者认为该计划有助于应对挑战、深入了解自己的行为,并感觉自己具备了更好的技能来应对未来的挑战。描述性统计结果表明,PiB-HD 计划具有减轻压力和焦虑的潜力。结论事实证明,PiB-HD 计划对于 HD 患者的照顾者来说是可行的、可用的和可接受的。这些结果为进一步研究 PiB-HD 的有效性提供了方向,并可用于在提供 HD 护理的过程中为电子保健的部署提供建议。
{"title":"Evaluating the web-based ‘Partner in Balance’ program for informal caregivers of people with Huntington's disease: A pilot study","authors":"Maud M.J. Daemen ,&nbsp;Lizzy M.M. Boots ,&nbsp;Mayke Oosterloo ,&nbsp;Marjolein E. de Vugt ,&nbsp;Annelien A. Duits","doi":"10.1016/j.invent.2024.100782","DOIUrl":"10.1016/j.invent.2024.100782","url":null,"abstract":"<div><h3>Background</h3><div>Huntington's disease (HD) poses significant challenges for both affected individuals and their informal caregivers. With the progression of HD, caregivers frequently prioritize caring for the person with HD over their own well-being. ‘Partner in Balance’ (PiB) is an 8-week online self-management program guided by a personal coach, developed to help caregivers of people with HD cope with challenging situations and develop skills to increase resilience and prevent overburdening.</div></div><div><h3>Aims</h3><div>This pilot study evaluates the feasibility and preliminary effects of the PiB-HD program.</div></div><div><h3>Methods</h3><div>The study employed a pre-post design. Perceived feasibility by HD caregivers was evaluated using both quantitative and qualitative measures. Preliminary effects were based on self-report measures of self-efficacy, mastery, mood, quality of life, and capability to function. Coaches' evaluations were conducted using a questionnaire.</div></div><div><h3>Results</h3><div>In total, 18 caregivers completed the intervention. Findings demonstrate positive responses regarding the program's usability, relevance, and acceptability. Participants found the program helpful in addressing challenges, gaining insight into their actions, and feeling better equipped with skills to face future challenges. Descriptive statistics suggest that the PiB-HD program shows potential for reducing stress and anxiety. Additionally, coaches (<em>n</em> = 9) viewed the program positively for its usability, integration potential into their work, flexibility, and time efficiency.</div></div><div><h3>Conclusions</h3><div>The PiB-HD program proved to be feasible, usable and acceptable for caregivers of people with HD. These results provide directions for further research into the effectiveness of PiB-HD, and can already be utilized to advise on the deployment of eHealth in the provision of HD care.</div></div>","PeriodicalId":48615,"journal":{"name":"Internet Interventions-The Application of Information Technology in Mental and Behavioural Health","volume":"38 ","pages":"Article 100782"},"PeriodicalIF":3.6,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness and prediction of treatment adherence to guided internet-based cognitive behavioral therapy for health anxiety: A cohort study in routine psychiatric care 基于互联网的认知行为疗法治疗健康焦虑的效果和坚持治疗的预测:常规精神科护理中的队列研究
IF 3.6 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-10-16 DOI: 10.1016/j.invent.2024.100780
Susanna Österman , Erland Axelsson , Erik Forsell , Cecilia Svanborg , Nils Lindefors , Erik Hedman-Lagerlöf , Volen Z. Ivanov

Objective

Health anxiety, also known as hypochondriasis, is a common psychiatric disorder which leads to considerable distress and is associated with high societal costs. Internet-based cognitive behavioural therapy (ICBT) for health anxiety has demonstrated efficacy in randomized controlled trials (RCTs), but there is limited knowledge regarding its effectiveness in real-world settings. This study aimed to evaluate the clinical effectiveness of guided ICBT for health anxiety in routine psychiatric care, including symptom change, treatment adherence, and potential negative effects. Additionally, we explored predictors of treatment adherence.

Method

A longitudinal cohort study of 447 patients enrolled in 12 weeks of ICBT for health anxiety between 2018 and 2020 in an outpatient psychiatric clinic specializing in ICBT. Primary outcome measure was the 14-item Short Health Anxiety Inventory (SHAI-14) and a within-group design with repeated measures was utilized for the primary analysis.

Results

Participants showed significant improvements from pre- to post-treatment (d = 1.61). At post-treatment, 60 % (95 % CI 58–62) demonstrated statistically reliable change (RCI), and 44 % (95 % CI 42–46) were in remission. On average, participants completed 7 (SD = 4) out of 12 treatment modules. For each additional completed module, the mean reduction was 0.31 (95 % CI 0.10 to 0.54) points on the SHAI-14.

Conclusions

Guided ICBT for health anxiety can be effective when delivered within the context of routine psychiatric care. The study suggests that effect sizes are comparable with those in RCTs and higher treatment adherence is associated with better outcomes in health anxiety. ICBT could be used to increase availability to effective therapy for health anxiety.
目标健康焦虑症又称疑病症,是一种常见的精神疾病,会给患者带来极大的痛苦,并造成高昂的社会成本。基于互联网的健康焦虑认知行为疗法(ICBT)已在随机对照试验(RCT)中证明了其疗效,但对其在现实环境中的有效性了解有限。本研究旨在评估在常规精神科治疗中采用引导式 ICBT 治疗健康焦虑的临床效果,包括症状变化、治疗依从性和潜在的负面影响。此外,我们还探讨了治疗依从性的预测因素。方法在 2018 年至 2020 年期间,在一家专门从事 ICBT 的精神科门诊中,447 名患者参加了为期 12 周的 ICBT 健康焦虑纵向队列研究。主要结果测量指标为14项健康焦虑短量表(SHAI-14),并采用重复测量的组内设计进行主要分析。结果参与者从治疗前到治疗后都有显著改善(d = 1.61)。在治疗后,60%(95% CI 58-62)的患者出现了统计上可靠的变化(RCI),44%(95% CI 42-46)的患者病情得到缓解。参与者平均完成了 12 个治疗模块中的 7 个(SD = 4)。每多完成一个治疗模块,SHAI-14 的平均得分就会降低 0.31 分(95 % CI 0.10 至 0.54 分)。研究表明,ICBT 的疗效与 RCT 的疗效相当,而且治疗依从性越高,焦虑症的治疗效果越好。综合治疗焦虑症可用于增加有效治疗焦虑症的机会。
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引用次数: 0
Internet-based cognitive behavioural therapy for insomnia comorbid with chronic benign pain – A randomized controlled trial 基于互联网的认知行为疗法治疗合并慢性良性疼痛的失眠症--随机对照试验
IF 3.6 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-10-14 DOI: 10.1016/j.invent.2024.100781
K. Bothelius , S. Jernelöv , V. Kaldo , C. Lu , M.-M. Stråle , M. Jansson-Fröjmark

Background

Comorbid sleep disturbances are common among individuals with chronic pain, and Cognitive Behavioural Therapy for Insomnia (CBT-i) has proven effective for such individuals. Nonetheless, research on web-based CBT-i tailored for patients with both chronic pain and insomnia is limited. This study aimed to evaluate the feasibility and efficacy of internet-based CBT-i and to explore potential mechanisms underlying treatment outcomes.

Methods

In this study, 85 participants suffering from comorbid insomnia and chronic pain were randomized into two groups: Internet-based CBT for Insomnia (ICBT-i) and Internet-based Applied Relaxation (IAR). Both interventions spanned eight weeks, supported by therapeutic guidance throughout.

Results

Participation was modest, with an average module completion of 2.0 out of 8 for ICBT-i and 2.4 for IAR. Both interventions significantly alleviated insomnia symptoms on one of the insomnia measures post-treatment, without notable differences between them. Directly after treatment, IAR outperformed ICBT-i in reducing pain interference, anxiety, and in enhancing self-rated health, though these differences lessened at the 6-month follow-up. Potential therapeutic mechanisms may involve attenuating maladaptive sleep beliefs and augmenting sleep-related willingness.

Conclusions

The study encountered low engagement rates, with approximately one-third of participants not completing any module. The limited efficacy of ICBT-i may be due to low treatment involvement, with few patients completing key techniques like sleep compression and stimulus control. Despite the low adherence, both interventions yielded post-treatment improvements in insomnia symptoms, but to establish internet-based treatments for insomnia as a viable option in chronic pain management, patient engagement must be improved.
背景慢性疼痛患者普遍存在睡眠障碍,而失眠认知行为疗法(CBT-i)已被证明对这类患者有效。然而,针对慢性疼痛和失眠患者量身定制的基于网络的 CBT-i 研究还很有限。本研究旨在评估基于网络的 CBT-i 的可行性和疗效,并探索治疗结果的潜在机制。方法在本研究中,85 名同时患有失眠症和慢性疼痛的参与者被随机分为两组:基于互联网的失眠 CBT(ICBT-i)和基于互联网的应用放松(IAR)。结果参与率不高,ICBT-i 的平均模块完成率为 2.0(满分 8 分),IAR 的平均模块完成率为 2.4(满分 8 分)。在治疗后的失眠测量中,两种干预方法都能明显减轻失眠症状,但两者之间没有明显差异。治疗后,IAR 在减少疼痛干扰、焦虑和提高自我健康评价方面的表现优于 ICBT-i,但这些差异在 6 个月的随访中有所缩小。潜在的治疗机制可能包括减轻不良睡眠信念和增强与睡眠相关的意愿。结论该研究的参与率较低,约有三分之一的参与者没有完成任何模块。ICBT-i 的疗效有限可能是由于治疗参与度低,只有少数患者完成了睡眠压缩和刺激控制等关键技术。尽管坚持率较低,但这两种干预方法都能在治疗后改善失眠症状,但要将基于互联网的失眠治疗方法确立为慢性疼痛治疗的可行选择,必须提高患者的参与度。
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引用次数: 0
The Sleep Course: An inclusive trial examining the feasibility, acceptability, and preliminary efficacy of a digital sleep intervention for adults with self-reported sleep difficulties 睡眠课程:一项包容性试验,针对自我报告有睡眠困难的成年人,研究数字睡眠干预的可行性、可接受性和初步疗效
IF 3.6 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-10-05 DOI: 10.1016/j.invent.2024.100778
Amelia J. Scott, Taylor Hathway, Madelyne A. Bisby, Nickolai Titov, Blake F. Dear
Cognitive Behavioural Therapy for Insomnia (CBTi) is a well-established first-line treatment for insomnia and sleep difficulties, yet numerous barriers hinder its widespread adoption. One potential criticism of the existing evidence base for CBTi is that many trials exclude participants that would commonly be seen in in primary care, such as those aged over 65, with comorbid health conditions, or prescribed sleep medication. The current pilot study therefore aimed to assess the acceptability and efficacy of a brief, digitally delivered sleep intervention, the Sleep Course, using a broad range of participants. Participants (n = 74) completed the 6-week, 4-lesson intervention alongside measures of sleep disturbance, sleep-related impairment, depression, anxiety and sleep-wake patterns (via sleep diary). Generalized estimating equations analysis modelled change in participants' outcomes from pre- to post-treatment and 3-month follow-up, and subgroup analyses explored the role of possible moderators (e.g., age over 65, co-morbidities, and concurrent prescription medication use). The intervention was associated with good rates of satisfaction (79 %) and lesson completion (70 %). Results showed significant and large reductions in insomnia, sleep disturbance and associated symptoms (e.g., d = 1.06–1.37 change in insomnia symptoms). Evidence of high acceptability and clinical improvement was found irrespective of age, physical comorbidity, and sleep medication use. However, there was evidence of less improvement among those taking medications or having tried psychological treatment in the past. These results provide strong preliminary evidence for the intervention as an acceptable, efficacious and scalable treatment for a broad range of participants with sleep difficulties. Larger randomised controlled trials are needed.
失眠认知行为疗法(CBTi)是治疗失眠和睡眠障碍的一种行之有效的一线疗法,但有许多障碍阻碍了它的广泛采用。CBTi现有证据基础的一个潜在诟病是,许多试验排除了初级保健中常见的参与者,如65岁以上、有合并症或服用睡眠药物的患者。因此,目前的试点研究旨在通过广泛的参与者来评估简短的数字式睡眠干预--"睡眠课程"--的可接受性和疗效。参与者(n = 74)在完成为期 6 周、共 4 课时的干预措施的同时,还对睡眠障碍、睡眠相关损伤、抑郁、焦虑和睡眠-觉醒模式(通过睡眠日记)进行了测量。广义估计方程分析模拟了参与者从治疗前到治疗后以及3个月随访期间的结果变化,分组分析探讨了可能的调节因素(如65岁以上、合并疾病和同时使用处方药)的作用。干预的满意率(79%)和课程完成率(70%)都很高。结果表明,失眠、睡眠障碍和相关症状明显大幅减少(例如,失眠症状的变化d = 1.06-1.37)。有证据表明,无论年龄、身体合并症和睡眠药物使用情况如何,该疗法都具有很高的可接受性和临床改善效果。不过,有证据表明,那些正在服用药物或过去曾尝试过心理治疗的人的症状改善程度较低。这些结果提供了有力的初步证据,证明该干预方法是一种可接受、有效且可推广的治疗方法,适用于有睡眠障碍的广大参与者。还需要进行更大规模的随机对照试验。
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引用次数: 0
Online social platform engagement by young treatment seekers in a digital vaping cessation intervention: Effects on confidence in the ability to quit vaping and vaping abstinence 数字化戒烟干预中青年戒烟者参与在线社交平台的情况:对戒烟能力和戒烟信心的影响
IF 3.6 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-10-04 DOI: 10.1016/j.invent.2024.100779
Elizabeth K. Do , Sarah Cha , Shreya Tulsiani , Giselle Edwards , Linda Q. Yu , Michael S. Amato , Megan A. Jacobs , Elizabeth C. Hair

Background

The evidence-based vaping cessation program, This is Quitting (TIQ), has been found to be effective in promoting abstinence among young people who use e-cigarettes.

Purpose

To estimate acceptability and engagement with Discord among treatment seeking youth and young adults and assess the benefit of adding an online social platform via Discord to TIQ.

Methods

Between February and March 2023, 527 TIQ participants (aged 13–24 years) were invited to join Discord with other TIQ users (TIQ Discord). Participants completed two online surveys, at baseline and 1-month post study enrollment. Descriptive statistics were used to describe acceptability and engagement with TIQ Discord. Chi-square, Fisher's exact, and t-tests were used to compare changes in confidence in ability to quit and vaping abstinence across those who joined and engaged with TIQ Discord, compared to those receiving TIQ only.

Results

Among the n = 319 who were invited to TIQ Discord and provided follow-up data, 57.4 % joined. Among those who joined (n = 183), 61.7 % engaged with TIQ Discord by contributing at least one message or reaction. The mean number of contributed messages was 4.0 (median = 1, range = 1 to 51) and reactions was 0.31 (median = 0, range = 0 to 14). Engaging with TIQ Discord was positively associated with increased confidence in quitting at follow-up (p-value = 0.02), but vaping abstinence at follow-up did not differ (p-value = 0.87).

Discussion

Over half of participants who were invited to TIQ Discord joined – indicating high acceptability and an uptake rate that is higher than what is typically observed for online cessation communities. Engagement was positively associated with proximal outcomes, but self-selection prevents causal attribution. Pilot study results suggest acceptability of Discord for providing digital cessation support to young people in combination with a text-message cessation intervention.
背景以证据为基础的电子烟戒烟计划 "这就是戒烟(TIQ)"已被发现能有效促进使用电子烟的年轻人戒烟。目的评估寻求治疗的青少年和年轻成年人对 Discord 的接受度和参与度,并评估通过 Discord 在 TIQ 中添加在线社交平台的益处。方法在 2023 年 2 月至 3 月期间,邀请 527 名 TIQ 参与者(13-24 岁)与其他 TIQ 用户一起加入 Discord(TIQ Discord)。参与者分别在基线和研究注册后 1 个月内完成了两次在线调查。描述性统计用于描述对 TIQ Discord 的接受度和参与度。使用卡方检验、费雪精确检验和 t 检验来比较加入并参与 TIQ Discord 的人与只接受 TIQ 的人在戒烟能力和禁烟信心方面的变化。在加入者(n = 183)中,61.7% 的人参与了 TIQ Discord,至少贡献了一条信息或作出了反应。贡献的消息平均数量为 4.0(中位数 = 1,范围 = 1 至 51),反应平均数量为 0.31(中位数 = 0,范围 = 0 至 14)。参与 TIQ Discord 与随访时戒烟信心的增加呈正相关(p 值 = 0.02),但随访时的吸烟戒断率没有差异(p 值 = 0.87)。参与度与近端结果呈正相关,但自我选择阻碍了因果关系。试点研究结果表明,Discord 与短信戒烟干预相结合,可为年轻人提供数字戒烟支持。
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引用次数: 0
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Internet Interventions-The Application of Information Technology in Mental and Behavioural Health
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