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Readiness for mHealth interventions in Jordan: Refugee camp and urban community survey 约旦移动医疗干预的准备情况:难民营和城市社区调查
IF 4.3 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-05-08 DOI: 10.1016/j.invent.2024.100746
Dror Ben-Zeev , Alexa Beaulieu , Jessy Guler , Anna Larsen , Ahmad Bawaneh

Jordan hosts one of the largest populations of refugees in the world. This study evaluated the capacity, infrastructure, and interest in mobile health interventions to address unmet mental health needs among refugees and non-refugees in Jordan. We surveyed 209 (141 refugees) adults and youth in urban, rural, and refugee camp settings. Survey results indicated that mobile device ownership was lower among refugees than non-refugees (71 % vs. 100 %, respectively). Refugee phone users had less access to smartphones than non-refugees (75 % vs. 96 %, respectively). Refugees and non-refugees reported using mobile devices for diverse activities including calling (83 % vs. 100 %, respectively), texting (28 % vs. 87 %, respectively) social media (45 % vs. 94 %, respectively), watching videos (23 % vs. 90 %, respectively), and studying (34 % vs. 72 %, respectively). Most respondents had reliable access to electricity (75 % vs. 99 %, respectively) and to mobile-cellular service (67 % vs. 97 %, respectively). Refugees and non-refugees differed substantially in their access to WiFi (14 % vs. 91 %, respectively). Both groups identified anger, anxiety, depression, traumatic memories, and eating problems as the most common mental health problems in their communities. Approximately half of refugees (44 %) and non-refugees (50 %) reported that their communities had insufficient or no access to mental health resources. Most refugees (78 %) and non-refugee (87 %) believed that using mobile devices to provide support for people with mental health conditions would be helpful. Overall, both groups' reported access to mobile technologies and openness to digital mental health treatment options suggest that mHealth interventions may be feasible and welcomed in these communities.

约旦是世界上难民人口最多的国家之一。这项研究评估了移动医疗干预的能力、基础设施和兴趣,以解决约旦难民和非难民未得到满足的心理健康需求。我们对城市、农村和难民营环境中的 209 名成人和青年(141 名难民)进行了调查。调查结果显示,难民的移动设备拥有率低于非难民(分别为 71% 和 100%)。难民手机用户使用智能手机的比例低于非难民(分别为 75% 对 96%)。难民和非难民都表示使用移动设备进行各种活动,包括打电话(分别为 83 % 对 100 %)、发短信(分别为 28 % 对 87 %)、社交媒体(分别为 45 % 对 94 %)、看视频(分别为 23 % 对 90 %)和学习(分别为 34 % 对 72 %)。大多数受访者都有可靠的电力供应(分别为 75 % 对 99 %)和移动电话服务(分别为 67 % 对 97 %)。难民和非难民在使用 WiFi 方面差别很大(分别为 14% 和 91%)。两个群体都认为愤怒、焦虑、抑郁、创伤记忆和饮食问题是他们社区中最常见的心理健康问题。大约一半的难民(44%)和非难民(50%)表示,他们所在的社区没有足够的或根本没有心理健康资源。大多数难民(78%)和非难民(87%)认为,使用移动设备为有心理健康问题的人提供支持会有所帮助。总体而言,这两个群体所报告的对移动技术的使用情况以及对数字心理健康治疗方案的开放程度表明,移动医疗干预措施在这些社区是可行的,也是受欢迎的。
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引用次数: 0
Revealing the source: How awareness alters perceptions of AI and human-generated mental health responses 揭示源头:认识如何改变对人工智能和人类产生的心理健康反应的看法
IF 4.3 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-04-27 DOI: 10.1016/j.invent.2024.100745
Gagan Jain , Samridhi Pareek , Per Carlbring

In mental health care, the integration of artificial intelligence (AI) into internet interventions could significantly improve scalability and accessibility, provided that AI is perceived as being as effective as human professionals. This longitudinal study investigates the comparative perceptions of ChatGPT and human mental health support professionals across three dimensions: authenticity, professionalism, and practicality. Initially, 140 participants evaluated responses from both sources without knowing their origin, revealing that AI-generated responses were rated significantly higher across all dimensions. Six months later, the same cohort (n = 111) reassessed these messages with the source of each response disclosed, aiming to understand the impact of source transparency on perceptions and trust towards AI. The results indicate a shift in perception towards human responses, only in terms of authenticity (Cohen's d = 0.45) and reveal a significant correlation between trust in AI and its practicality rating (r = 0.25), but not with authenticity or professionalism. A comparative analysis between blind and informed evaluations revealed a significant shift in favour of human response ratings (Cohen's d = 0.42–0.57), while AI response ratings experienced minimal variation. These findings highlight the nuanced acceptance and role of AI in mental health support, emphasizing that the disclosure of the response source significantly shapes perceptions and trust in AI-generated assistance.

在心理健康护理领域,将人工智能(AI)整合到互联网干预措施中可以显著提高可扩展性和可及性,前提是人们认为人工智能与人类专业人员一样有效。这项纵向研究调查了 ChatGPT 和人类心理健康支持专业人员在真实性、专业性和实用性三个方面的比较看法。最初,140 名参与者在不知道两种来源的回复来源的情况下对其进行了评估,结果显示,人工智能生成的回复在所有维度上的评分都明显更高。六个月后,同一批参与者(n = 111)重新评估了这些信息,并披露了每条回复的来源,旨在了解来源透明度对人工智能认知和信任的影响。结果表明,仅在真实性方面,人们对人工回复的看法发生了转变(Cohen's d = 0.45),并揭示了人工智能信任度与其实用性评级之间的显著相关性(r = 0.25),但与真实性或专业性无关。对盲评和知情评测的比较分析表明,人工智能的响应评级在很大程度上倾向于人类(Cohen's d = 0.42-0.57),而人工智能的响应评级变化极小。这些研究结果突显了人工智能在心理健康支持中的细微接受度和作用,强调了回复来源的公开性在很大程度上影响了人们对人工智能生成的援助的看法和信任。
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引用次数: 0
Guided web app intervention for reducing symptoms of depression in postpartum women: Results of a feasibility randomized controlled trial 减少产后妇女抑郁症状的指导性网络应用干预:可行性随机对照试验的结果
IF 4.3 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-04-25 DOI: 10.1016/j.invent.2024.100744
Pamela Franco , Marcia Olhaberry , Saskia Kelders , Antonia Muzard , Pim Cuijpers

Background

Chile faces a significant postpartum depression prevalence and treatment gap, necessitating accessible interventions. While cognitive-behavioral internet-based interventions have proven effective in high-income countries, this field is underdeveloped in Chile. Based on the country's widespread use of digital technology, a guided 8-week cognitive-behavioral web app intervention named “Mamá, te entiendo” was developed.

Objective

This study aimed to assess the acceptability and feasibility of “Mamá, te entiendo”, for reducing depressive symptomatology in postpartum women.

Methods

Sixty-five postpartum women with minor or major depression were randomly assigned to either intervention or waitlist. Primary outcomes centered on study feasibility, intervention feasibility, and acceptability. Semi-structured interviews with a sub-sample enriched the understanding of participants' experiences. Secondary outcomes included mental health variables assessed at baseline, post-intervention, and 1-month follow-up.

Results

Chilean women displayed great interest in the intervention. 44.8 % of participants completed the intervention. Participants reported high satisfaction and engagement levels, with interviewees highlighting the value of the intervention's content, exercises, and therapist's feedback. However, preliminary efficacy analysis didn't reveal a significant interaction between group and time for outcome measures.

Discussion

This research represents a pioneering effort in Chile to evaluate an internet-based intervention for postpartum depression symptoms. The demonstrated feasibility and acceptability highlight the potential of integrating technology-driven approaches into mental health interventions. However, the intervention did not demonstrate superiority, as both groups exhibited similar positive progress in several outcomes. Therefore, the following research phase should involve a larger and more diverse sample to assess the intervention's effectiveness, identify influencing factors, and determine the individuals who benefit the most.

背景智利的产后抑郁症发病率和治疗缺口都很大,因此有必要采取干预措施。在高收入国家,基于互联网的认知行为干预被证明是有效的,但在智利,这一领域却发展不足。本研究旨在评估 "Mamá, te entiendo "在减少产后妇女抑郁症状方面的可接受性和可行性。方法 65 名患有轻度或重度抑郁症的产后妇女被随机分配到干预或等待名单中。主要结果集中在研究可行性、干预可行性和可接受性上。对部分样本进行的半结构化访谈丰富了对参与者经历的了解。次要结果包括基线、干预后和 1 个月随访时评估的心理健康变量。44.8%的参与者完成了干预。参与者的满意度和参与度都很高,受访者强调了干预内容、练习和治疗师反馈的价值。然而,初步的疗效分析并未显示出组别与时间之间在结果测量上的显著交互作用。已证明的可行性和可接受性凸显了将技术驱动方法整合到心理健康干预中的潜力。然而,干预措施并没有显示出优越性,因为两组在几项结果上都取得了类似的积极进展。因此,下一阶段的研究应涉及更大、更多样化的样本,以评估干预的有效性,找出影响因素,并确定受益最大的人群。
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引用次数: 0
Telephone support vs. self-guidance in an Internet-based self-administered psychological program for the treatment of depression: Protocol for a hybrid type 1 effectiveness-implementation randomized controlled trial 基于互联网的抑郁症治疗自控心理方案中的电话支持与自我指导:混合型 1 效应-实施随机对照试验方案
IF 4.3 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-04-20 DOI: 10.1016/j.invent.2024.100742
Rosa Lorente-Català , Pablo Font-Furnieles , Raquel Escriva-Sanchis , Clara Bertó-García , Pere Vera-Albero , Azucena García-Palacios

Background

Depression is already the leading psychological disability around the world, impairing daily life, well-being, and social functioning and leading to personal and social costs. Despite the effectiveness of Evidence-Based Psychological Practices (EBPP), a significant percentage of depressive individuals remain untreated, especially in Primary Care (PC) settings in Spain. There are numerous barriers that limit access to EBPPs, including high costs, professional training, and adherence problems. Information and Communication Technologies (ICTs) offer a cost-effective way to disseminate and scale EBPPs to address these barriers. The iCBT program Smiling is Fun has been demonstrated to be a cost-effective treatment for depression in various Randomized Control Trials. However, adherence and implementation problems in real-world settings need to be addressed. Implementation research can help evaluate these challenges by identifying facilitators and barriers to the implementation process in PC. In this regard, including human support has been pointed out as a possible key factor in addressing the population's mental health needs and promoting treatment adherence.

Objective

The current study aims to examine the effectiveness, adherence rates, and implementation process of Smiling is Fun to address depression in a PC setting considering the influence of telephone support vs no support.

Methods

The proposed research is a Hybrid Effectiveness-Implementation Type I study, with a two-armed randomized controlled design, which will test a clinical intervention for major depressive disorder while gathering information on its implementation in a real-world setting. The study will include adult patients with mild to moderate symptoms of depression. Participants will be randomly assigned to one of two groups: self-applied psychotherapy or self-applied psychotherapy with psychotherapeutic telephone support. The trial will recruit 110 patient participants, with a loss-to-follow-up rate of 30 %.

Discussion

A study protocol for a hybrid effectiveness-implementation study is presented with the aim to assess the implementation of Smiling is Fun for the treatment of depression in PC. The study evaluates the influence of telephone support during a self-administered intervention compared to unguided self-administration. The main goal is to address the barriers and facilitators of the implementation process and to promote treatment adherence. Ultimately, the results of the study could help in the uptake of sustainable resources so that the population could gain better access to psychological interventions in mental health services.

Registration

ClinicalTrials.gov; NCT06230237.

背景抑郁症已经成为全世界最主要的心理残疾,影响着人们的日常生活、幸福感和社会功能,并导致个人和社会成本增加。尽管循证心理疗法(EBPP)效果显著,但仍有相当比例的抑郁症患者未得到治疗,尤其是在西班牙的初级保健(PC)机构中。有许多障碍限制了 EBPP 的使用,包括高昂的费用、专业培训和坚持问题。信息和通信技术(ICT)为传播和推广 EBPPs 提供了一种具有成本效益的方法,以解决这些障碍。在多项随机对照试验中,iCBT 项目 "微笑很有趣 "已被证明是一种经济有效的抑郁症治疗方法。然而,在现实环境中的坚持和实施问题仍有待解决。实施研究可以通过确定 PC 实施过程中的促进因素和障碍,帮助评估这些挑战。本研究旨在考察 "微笑很有趣 "在 PC 环境中治疗抑郁症的有效性、依从率和实施过程,同时考虑电话支持与无支持的影响。方法本研究是一项混合有效性-实施 I 型研究,采用双臂随机对照设计,将测试重度抑郁障碍的临床干预措施,同时收集其在实际环境中的实施信息。研究对象包括轻度至中度抑郁症状的成年患者。参与者将被随机分配到两组中的一组:自我应用心理疗法或自我应用心理疗法加电话心理治疗支持。该试验将招募 110 名患者参加,随访损失率为 30%。讨论本文介绍了一项混合效果-实施研究的研究方案,旨在评估 "微笑很有趣 "在 PC 抑郁症治疗中的实施情况。与无指导的自我管理相比,该研究评估了在自我管理干预过程中电话支持的影响。主要目的是解决实施过程中的障碍和促进因素,并提高治疗的依从性。最终,研究结果将有助于可持续资源的吸收,从而使人们能更好地获得心理健康服务中的心理干预措施。
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引用次数: 0
The use of coaching in smartphone app-based cognitive behavioral therapy for body dysmorphic disorder 在基于智能手机应用程序的身体畸形障碍认知行为疗法中使用教练技术
IF 4.3 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-04-18 DOI: 10.1016/j.invent.2024.100743
Emily E. Bernstein , Jennifer L. Greenberg , Hilary Weingarden , Ivar Snorrason , Berta Summers , Jasmine Williams , Rachel Quist , Joshua Curtiss , Oliver Harrison , Sabine Wilhelm

Background

Body dysmorphic disorder (BDD) is severe and undertreated. Digital mental health could be key to expanding access to evidence-based treatments, such as cognitive behavioral therapy for BDD (CBT-BDD). Coach guidance is posited to be essential for effective uptake of digital interventions. However, little is known about how different patients may use coaching, what patterns correspond to meaningful outcomes, and how to match coaching to patient needs.

Methods

Participants were 77 adults who received a 12-week guided smartphone CBT-BDD. Bachelor's-level coaches were available via asynchronous messaging. We analyzed the 400 messages sent by users to coaches during treatment. Message content was coded using the efficiency model of support (i.e., usability, engagement, fit, knowledge, and implementation). We aimed to clarify when and for what purposes patients with BDD used coaching, and if we can meaningfully classify patients by these patterns. We then assessed potential baseline predictors of coach usage, and whether distinct patterns relate to clinical outcomes.

Results

Users on average sent 5.88 messages (SD = 4.51, range 1–20) and received 9.84 (SD = 5.74, range 2–30). Regarding frequency of sending messages, latent profile analysis revealed three profiles, characterized by: (1) peak mid-treatment (16.88 %), (2) bimodal/more communication early and late in treatment (10.39 %), and (3) consistent low/no communication (72.73 %). Regarding content, four profiles emerged, characterized by mostly (1) engagement (51.95 %), (2) fit (15.58 %), (3) knowledge (15.58 %), and (4) miscellaneous/no messages (16.88 %). There was a significant relationship between frequency profile and age, such that the early/late peak group was older than the low communication group, and frequency profile and adherence, driven by the mid-treatment peak group completing more modules than the low contact group. Regarding content, the engagement and knowledge groups began treatment with more severe baseline symptoms than the fit group. Content profile was associated with dropout, suggesting higher dropout rates in the miscellaneous/no contact group and reduced rates in the engagement group. There was no relationship between profile membership and other outcomes.

Discussion

The majority of participants initiated little contact with their coach and the most common function of communications was to increase engagement. Results suggest that older individuals may prefer or require more support than younger counterparts early in treatment. Additionally, whereas individuals using coaching primarily for engagement may be at lower risk of dropping out, those who do not engage at all may be at elevated risk. Findings can support more personalized, data-driven coaching protocols and more efficient allocation of coaching resources.

背景身体畸形障碍(BDD)是一种严重的疾病,而且治疗效果不佳。数字心理健康可能是扩大循证治疗(如 BDD 认知行为疗法 CBT-BDD)覆盖面的关键。教练指导被认为是有效采用数字干预措施的关键。然而,人们对不同患者如何使用教练指导、哪些模式与有意义的结果相对应以及如何使教练指导与患者需求相匹配等问题知之甚少。本科水平的教练可通过异步信息进行指导。我们分析了用户在治疗过程中发送给教练的 400 条信息。我们使用支持效率模型(即可用性、参与度、契合度、知识和实施)对信息内容进行了编码。我们旨在明确 BDD 患者何时及出于何种目的使用教练,以及我们能否根据这些模式对患者进行有意义的分类。然后,我们评估了教练使用的潜在基线预测因素,以及不同模式是否与临床结果相关。结果患者平均发送 5.88 条信息(SD = 4.51,范围 1-20),收到 9.84 条信息(SD = 5.74,范围 2-30)。关于发送信息的频率,潜在特征分析显示出三种特征:(1) 在治疗中期达到高峰(16.88%),(2) 在治疗早期和晚期出现双峰/更多交流(10.39%),(3) 持续低交流/无交流(72.73%)。在内容方面,出现了四种情况,主要特点是:(1) 参与(51.95 %),(2) 适合(15.58 %),(3) 知识(15.58 %),(4) 杂项/无信息(16.88 %)。频率分布和年龄之间存在明显的关系,早期/晚期高峰组的年龄大于低沟通组;频率分布和坚持率之间也存在明显的关系,中期治疗高峰组比低接触组完成了更多的模块。在内容方面,参与组和知识组开始治疗时的基线症状比适应组严重。内容特征与辍学率有关,表明杂项/未接触组的辍学率较高,而参与组的辍学率较低。讨论大多数参与者很少主动与教练联系,最常见的沟通功能是提高参与度。结果表明,在治疗初期,老年人可能比年轻人更喜欢或需要更多的支持。此外,主要通过教练提高参与度的人辍学风险可能较低,而完全不参与的人辍学风险可能较高。研究结果有助于制定更加个性化、以数据为导向的辅导方案,并更有效地分配辅导资源。
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引用次数: 0
Effects of a single session low-threshold digital intervention for procrastination behaviors among university students (Focus): Findings from a randomized controlled trial 单次低阈值数字干预对大学生拖延行为的影响(聚焦):随机对照试验结果
IF 4.3 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-04-08 DOI: 10.1016/j.invent.2024.100741
Katarina Åsberg , Marie Löf , Marcus Bendtsen

Introduction

Procrastination behaviors are common among university students, and have been found to be associated with stress, symptoms of depression, anxiety, and poorer academic performance. There is a need for interventions that can reach students at scale, and therefore this study aimed to estimate the effects of a single session low-threshold digital intervention (Focus) for procrastination behaviors among university students in Sweden.

Methods and analysis

A two-arm, parallel groups (1:1), single blind randomized controlled trial was conducted between February 8 to April 26, 2023. The study used email to invite university students across Sweden to participate in the trial. Both the intervention and the control group were invited to assess their current procrastination behaviors using the Pure Procrastination Scale (PPS). The intervention group immediately received feedback and behavior change advice by means of an interactive website, while the control group was shown their total PPS score without any further feedback. Students were included in the study if they scored 20 points or more on the PPS. Our primary outcome was procrastination behavior measured at 2 months post-randomization. Analyses were conducted using multilevel regression models estimated with Bayesian inference.

Results

A total of 2209 participants (intervention: 1109, control: 1100) were randomized. The average age of participants was 26.4 years (SD = 7.8) and 65 % were women (n = 1442). The mean PPS score at baseline was 35.6 points (of a maximum of 60). Primary outcome data were available for 45 % (n = 498) of the intervention group and 55 % (n = 601) of the control group. The evidence suggested no marked difference between groups regarding any of the outcomes, although there was weak evidence of lower physical activity in the intervention group. Qualitative findings from open-ended responses uncovered a variety of views on procrastination and perceived problems that may follow. Those not feeling supported by Focus explained having troubles adopting the advice given and converting their intentions into action without more continuous support.

Conclusions

Access to a single session of feedback and behavior change advice by means of an interactive website did not produce differential self-reported procrastination among university students who took the opportunity to self-assess their behaviors. The findings are limited by assessment reactivity due to screening at baseline and attrition to follow-up.

导言:拖延行为在大学生中很常见,并被发现与压力、抑郁症状、焦虑症和较差的学习成绩有关。因此,本研究旨在估算单次低阈值数字干预(Focus)对瑞典大学生拖延行为的影响。方法与分析2023年2月8日至4月26日期间进行了一项双臂、平行组(1:1)、单盲随机对照试验。研究通过电子邮件邀请瑞典全国的大学生参与试验。干预组和对照组都受邀使用 "纯粹拖延量表"(PPS)评估他们当前的拖延行为。干预组立即通过互动网站获得反馈和行为改变建议,而对照组则只显示其 PPS 总分,不提供任何进一步的反馈。如果学生在 PPS 上的得分达到或超过 20 分,则被纳入研究范围。我们的主要研究结果是随机分组后 2 个月的拖延行为测量结果。我们使用贝叶斯推理估计的多层次回归模型进行了分析。参与者的平均年龄为 26.4 岁(SD = 7.8),65% 为女性(n = 1442)。基线时的 PPS 平均分为 35.6 分(最高分为 60 分)。干预组和对照组的主要结果数据分别为 45%(n = 498)和 55%(n = 601)。尽管有微弱的证据表明干预组的体育活动量较低,但证据表明组间在任何结果上都没有明显差异。从开放式回答中得出的定性结果揭示了对拖延和可能随之产生的问题的各种看法。那些没有得到 Focus 支持的人解释说,如果没有更多持续的支持,他们很难采纳所给出的建议,也很难将自己的意图转化为行动。由于基线筛选和随访时的自然减员,研究结果受到了评估反应性的限制。
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引用次数: 0
Efficacy of a web-based psychoeducational intervention, Fex-can sex, for young adult childhood cancer survivors with sexual dysfunction: A randomized controlled trial 基于网络的心理教育干预 "Fex-can sex "对患有性功能障碍的年轻成年儿童癌症幸存者的疗效:随机对照试验
IF 4.3 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-04-07 DOI: 10.1016/j.invent.2024.100739
Kristina Fagerkvist , Kirsi Jahnukainen , Lisa Ljungman , Claudia Lampic , Lena Wettergren

Background

No web-based interventions addressing sexual problems are available for young adult survivors of childhood cancer.

Aim

This study aimed to test the efficacy of a web-based psychoeducational intervention, Fex-Can Sex, to alleviate sexual problems in young adults treated for cancer during childhood.

Method

This randomized controlled trial tested the effects of a 12-week, self-help, web-based intervention. Young adults (aged 19–40) reporting sexual dysfunction were drawn from a population-based national cohort of childhood cancer survivors and randomized to either an intervention group (IG, n = 142) or a wait-list control group (CG, n = 136). The primary outcome was ‘Satisfaction with sex life’ assessed by the PROMIS® SexFS v 2.0. Secondary outcomes included other SexFS domains, body image (BIS), emotional distress (HADS), health-related quality of life (EORTC QLQ-C30), and sex-related self-efficacy. Surveys were completed at baseline (T0), directly after the intervention (T1), and three months later (T2). The effects of the intervention were tested using t-test and linear mixed models, including intention-to-treat (ITT) and subgroups analysis. Adherence was based on log data extracted from the website system. The intervention included an open-ended question about perceived sexual problems.

Results

No effect of the intervention was found in the primary outcome. Regarding secondary outcomes, the IG reported less vaginal dryness (Lubrication subscale) than the CG at T1 (p = 0.048) and T2 (p = 0.023). Furthermore, at T1, the IG reported less emotional distress than the CG (p = 0.047). Subgroup analyses showed that those with greater sexual problems at T0 improved over time (T1 and T2), regardless of group allocation. Overall, adherence to the intervention was low and participants' activity levels did not change the results. Additionally, some members of the IG reported increased understanding and acceptance of their sexual problems.

Conclusion

The Fex-Can Sex intervention shows potential to improve sexual function, especially among those with greater dysfunction. To increase adherence and effect, we recommend the intervention to be further developed including more tailored content.

Clinical trial registration

ISRCTN Registry, trial number: 33081791 (registered on November 27, 2019).

背景目前还没有针对儿童癌症年轻幸存者性问题的网络干预措施。方法这项随机对照试验测试了为期 12 周的自助式网络干预措施的效果。报告性功能障碍的年轻人(19-40 岁)来自全国儿童癌症幸存者人群,他们被随机分配到干预组(IG,n = 142)或候补对照组(CG,n = 136)。主要结果是 "性生活满意度",由 PROMIS® SexFS v 2.0 评估。次要结果包括其他 SexFS 领域、身体形象 (BIS)、情绪困扰 (HADS)、健康相关生活质量 (EORTC QLQ-C30) 和性相关自我效能。调查分别在基线(T0)、干预后(T1)和三个月后(T2)完成。干预效果采用 t 检验和线性混合模型进行检验,包括意向治疗(ITT)和亚组分析。依从性基于从网站系统中提取的日志数据。干预措施包括一个关于感知到的性问题的开放式问题。关于次要结果,在 T1(p = 0.048)和 T2(p = 0.023)时,IG 报告的阴道干涩程度(润滑分量表)低于 CG。此外,在 T1 阶段,IG 报告的情绪困扰少于 CG(p = 0.047)。分组分析表明,在 T0 阶段性问题较严重的患者,随着时间的推移(T1 和 T2),情况有所改善,与分组无关。总体而言,干预的坚持率较低,参与者的活动水平并没有改变结果。结论 "Fex-Can 性 "干预显示出改善性功能的潜力,尤其是对那些有较大性功能障碍的人。为了提高依从性和效果,我们建议进一步开发该干预措施,包括更多量身定制的内容。临床试验注册ISRCTN Registry,试验编号:33081791(注册日期:2019年11月27日)。
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引用次数: 0
Effectiveness of internet-delivered cognitive behavioural therapy for anxiety and obsessive-compulsive disorders within routine clinical care in rural Sweden 在瑞典农村地区的常规临床护理中,通过互联网提供认知行为疗法治疗焦虑症和强迫症的效果
IF 4.3 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-04-06 DOI: 10.1016/j.invent.2024.100738
Sarah Vigerland , Sandra Fredlander , Kristina Aspvall , Maral Jolstedt , Fabian Lenhard , David Mataix-Cols , Brjánn Ljótsson , Eva Serlachius

Few studies have evaluated the implementation of ICBT in regular child and adolescent mental health services (CAMHS). This study aimed to explore the acceptability, feasibility, and effectiveness of ICBT for children and adolescents with anxiety disorders and obsessive-compulsive disorder (OCD) within a rural CAMHS. The study also explored outcome predictors and long-term outcomes.

Eighty-three participants were consecutively recruited from a non-specialized CAMHS in Region Jämtland Härjedalen in northern Sweden. Therapist-guided ICBT was offered during 12 weeks to children aged 8–17 with an anxiety disorder or OCD. Acceptability and feasibility measures included treatment adherence, treatment satisfaction, and adverse events. The primary outcome measure was the Clinical Global Impression–Severity. Secondary measures of effectiveness included clinician-, self-, and parent-ratings of symptom severity and functional impairment. Assessments were completed at baseline, post-treatment, and three-month follow-up (primary endpoint). A two-year follow up was conducted using medical records. Potential predictors included both patient characteristics and treatment variables.

Results indicated that ICBT was both acceptable and feasible according to study measures. Statistically significant improvements were found from baseline to the three-month follow-up on clinician rated severity (B [SE] = −0.92 [0.09]; p < .001), as well as on all secondary measures. Forty-three percent of participants no longer fulfilled criteria for their principal disorder at the three-month follow-up. No serious adverse events were reported. Clinical improvement was highest among children with higher functioning at baseline (B [SE] = −0.05 [0.02]; p < .05). Forty-six percent of participants had been in contact with CAMHS during the two-year follow-up period, mainly for reasons other than their initial diagnosis. Findings suggest that ICBT could be an acceptable and feasible treatment option for young people with anxiety disorders and OCD in rural non-specialized CAMHS settings. Further studies are needed to confirm treatment effectiveness in this setting. Trial registration: NCT02926365.

很少有研究对 ICBT 在常规儿童和青少年心理健康服务(CAMHS)中的实施情况进行评估。本研究旨在探讨 ICBT 在农村儿童和青少年心理健康服务机构中对患有焦虑症和强迫症(OCD)的儿童和青少年的可接受性、可行性和有效性。该研究还对结果预测因素和长期结果进行了探讨。研究人员从瑞典北部耶姆特兰海耶达伦地区的一家非专业儿童和青少年心理健康服务机构连续招募了 83 名参与者。在治疗师指导下,对 8-17 岁患有焦虑症或强迫症的儿童进行了为期 12 周的 ICBT 治疗。可接受性和可行性测量包括治疗依从性、治疗满意度和不良事件。主要结果测量指标是临床总体印象-严重程度。疗效的次要测量指标包括临床医生、自我和家长对症状严重程度和功能障碍的评分。评估在基线、治疗后和三个月随访(主要终点)时完成。利用医疗记录进行了为期两年的随访。潜在的预测因素包括患者特征和治疗变量。结果表明,根据研究措施,综合心理治疗是可接受和可行的。从基线到三个月随访期间,临床医生评定的严重程度(B [SE] = -0.92 [0.09]; p <.001)以及所有次要测量指标均有明显改善。43%的参与者在三个月的随访中不再符合其主要障碍的标准。没有严重不良事件的报告。基线功能较高的儿童的临床改善程度最高(B [SE] = -0.05 [0.02]; p <.05)。在为期两年的随访期间,46% 的参与者曾与儿童心理卫生服务机构有过接触,主要原因并非最初的诊断。研究结果表明,对于在农村非专业儿童青少年心理健康服务机构中患有焦虑症和强迫症的青少年来说,综合心理治疗是一种可以接受且可行的治疗方法。在这种情况下,还需要进一步的研究来确认治疗效果。试验注册:NCT02926365.
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引用次数: 0
Exploring individual's public trust in the NHS Test and Trace System – A pragmatic reflexive thematic analysis 探究个人对英国国家医疗服务系统(NHS)检验和追踪系统的公众信任--实用反思性专题分析
IF 4.3 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-04-04 DOI: 10.1016/j.invent.2024.100740
C.M. Babbage , H. Wagner , L. Dowthwaite , V. Portillo , E. Perez , J. Fischer

Context

Digital contact tracing uses automated systems and location technology embedded on smartphone software for efficient identification of individuals exposed to COVID-19. Such systems are only effective with high compliance, yet compliance is mediated by public trust in the system. This work explored the perception of individual's trust and expectation of the broader Test and Trace system in the United Kingdom (UK) with the upcoming release of the National Health Service's (NHS) COVID-19 app as a case example.

Methods

Twelve adults underwent online semi-structured interviews in August 2020, prior to public availability of the COVID-19 app. Pragmatic reflexive thematic analysis was applied inductively to explore common themes between participants, using an organic and recursive process (Braun & Clarke, 2019).

Results

Themes highlighted features of the technology that would be perceived to be trustworthy (Theme 1), and concerns relating to i) whether users would comply with a T&T system (Theme 2) and ii) how a T&T system would handle user's personal data (Theme 3). Two further themes built on aspects of automation within a T&T system and its impact on trust (Theme 4) and how the media altered perceptions of the T&T system (Theme 5).

Conclusions

Participants outlined the need for different user requirements that could be built into the NHS COVID-19 app that would support increased adherence. Concurrently, participants raised questions surrounding personal data and privacy of their data, plus the level of automated versus manual tasks, which impacted perception of trust in the app and wider system. Additionally, themes highlighted that T&T systems do not happen within a vacuum, but within a pre-existing environment influenced by variables such as the media and perception of other's compliance to T&T.

Implications

Since it's roll-out, controversies surrounding the UK T&T system include concerns about privacy, stigma and uptake. Considering the current piece of work, which anticipated similar concerns prior to public access to COVID-19 app, engaging with the public may have been an important step in improving the perception and compliance with the app. Principles fundamental to patient and public involvement (PPI) and Responsible Research and Innovation (RRI) such as the inclusion of the public in the early development of research and aligning the outcomes of research and innovation with broader societal values and expectations would have been well-applied to this system and should be applied to future autonomous systems requiring high public uptake.

背景数字接触追踪利用智能手机软件中嵌入的自动化系统和定位技术,有效识别接触 COVID-19 的个人。此类系统只有在高度合规的情况下才会有效,但合规性取决于公众对系统的信任度。这项研究以英国国家卫生服务系统(NHS)即将发布的 COVID-19 应用程序为例,探讨了英国个人对更广泛的检测和追踪系统的信任和期望。方法在 COVID-19 应用程序公开发布之前,12 名成年人于 2020 年 8 月接受了在线半结构式访谈。实事求是的反思性主题分析采用有机和递归的过程,以归纳的方式探索参与者之间的共同主题(Braun & Clarke, 2019)。结果主题强调了人们认为值得信赖的技术特征(主题 1),以及与 i) 用户是否会遵守 T&T 系统(主题 2)和 ii) T&T 系统将如何处理用户的个人数据(主题 3)有关的担忧。另外两个主题分别是 T&T 系统中的自动化及其对信任的影响(主题 4)以及媒体如何改变人们对 T&T 系统的看法(主题 5)。同时,参与者还提出了有关个人数据和数据隐私,以及自动化与人工任务水平的问题,这影响了对应用程序和更广泛系统的信任感。此外,这些主题还强调,T&T 系统并不是在真空中发生的,而是在受媒体和对其他人遵守 T&T 的看法等变量影响的原有环境中发生的。考虑到目前的工作在公众使用 COVID-19 应用程序之前就已经预见到了类似的问题,与公众接触可能是改善对该应用程序的看法和遵守情况的重要一步。患者与公众参与(PPI)和负责任的研究与创新(RRI)的基本原则,如让公众参与研究的早期开发,使研究与创新的成果与更广泛的社会价值观和期望相一致等,本应很好地应用于该系统,并应应用于未来需要大量公众使用的自主系统。
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引用次数: 0
Evaluation of effectiveness and acceptability of a psychological treatment for smoking cessation combined with a smartphone App: A pilot study 评估戒烟心理治疗与智能手机应用程序相结合的有效性和可接受性:试点研究
IF 4.3 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-03-30 DOI: 10.1016/j.invent.2024.100737
María Barroso-Hurtado, Ana López-Durán, Carmela Martínez-Vispo, Daniel Suárez-Castro, Elisardo Becoña

Despite the increasing number of mobile-based interventions to quit smoking over the last years, few studies have investigated the efficacy of smoking cessation interventions blended with smartphone Apps. The present pilot study aims to examine the preliminary effectiveness and acceptability of a cognitive-behavioral treatment combined with a smartphone App, compared to the same psychological treatment without the App. The sample comprised 206 treatment-seeking smokers, who were assigned to: 1) an experimental group receiving a cognitive-behavioral intervention combined with the “Non Fumo” App (n = 102), and 2) a control group receiving only the cognitive-behavioral intervention to quit smoking (n = 104). Results concerning the primary outcomes showed no significant differences between conditions in point-prevalence abstinence rates at 12-month follow-up (35.30 % in the experimental group vs. 31.70 % in the control group) and in treatment acceptability. Regarding the secondary outcomes, both groups obtained similar point-prevalence abstinence rates at the end of treatment (61.80 % vs. 65.40 %), at 3-month (42.20 % vs. 45.20 %, respectively) and 6-month follow-ups (37.30 % vs. 37.50 %). No significant differences were found between conditions in prolonged abstinence rates at 6-month (35.3 % vs. 35.6 %) and 12-month follow-ups (30.4 % vs. 26.9 %). Overall, good abstinence rates and treatment acceptability were obtained, although there were no significant differences between conditions. More research is needed to establish clear conclusions about the efficacy of psychological smoking cessation treatments blended with smartphone Apps.

尽管近年来基于手机的戒烟干预措施越来越多,但很少有研究调查了与智能手机应用程序相结合的戒烟干预措施的效果。本试验研究旨在考察认知行为疗法与智能手机应用程序相结合的初步有效性和可接受性,并与不使用应用程序的相同心理疗法进行比较。样本由 206 名寻求治疗的吸烟者组成,他们被分配到:1)实验组,接受认知行为治疗,同时使用智能手机应用程序;2)对照组,接受认知行为治疗,同时使用智能手机应用程序:1)接受认知行为干预与 "Non Fumo "应用程序相结合的实验组(102 人);2)仅接受认知行为干预戒烟的对照组(104 人)。有关主要结果的研究结果表明,在 12 个月的随访中,实验组与对照组在点戒烟率(实验组为 35.30%,对照组为 31.70%)和治疗可接受性方面没有明显差异。在次要结果方面,两组在治疗结束时(61.80% 对 65.40%)、3 个月随访时(42.20% 对 45.20%)和 6 个月随访时(37.30% 对 37.50%)的点戒断率相似。在 6 个月随访(35.3% 对 35.6%)和 12 个月随访(30.4% 对 26.9%)中,不同条件下的长期戒断率没有明显差异。总体而言,虽然治疗条件之间没有显著差异,但戒断率和治疗可接受性都不错。还需要进行更多的研究,才能对结合智能手机应用程序的心理戒烟疗法的疗效得出明确的结论。
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Internet Interventions-The Application of Information Technology in Mental and Behavioural Health
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