Pub Date : 2025-04-03eCollection Date: 2025-04-01DOI: 10.1055/s-0045-1804492
Anne Sailer, Igor Latich, Alexa O Levey
Pain is a complex interplay of psychological, immunological, and sensory experiential factors that leads to discomfort and physical suffering unique to each person. Uncontrolled pain greatly affects quality of life, a person's ability to function in society, and often results in increased healthcare costs. In order to appropriately treat a patient, knowledge of the different types of pain and various combinations of therapies is imperative. Cryoneurolysis is an important adjunctive therapy in pain management. When used in the appropriate clinical setting, it can decrease a patient's pain, opioid consumption, and improve quality of life. This article reviews common targets for cryoneurolysis based on patient pathology and discusses anatomic considerations to ensure the most efficacious and safe patient outcomes.
{"title":"Common Cryoneurolysis Targets in Pain Management: Indications, Critical Anatomy, and Potential Complications.","authors":"Anne Sailer, Igor Latich, Alexa O Levey","doi":"10.1055/s-0045-1804492","DOIUrl":"10.1055/s-0045-1804492","url":null,"abstract":"<p><p>Pain is a complex interplay of psychological, immunological, and sensory experiential factors that leads to discomfort and physical suffering unique to each person. Uncontrolled pain greatly affects quality of life, a person's ability to function in society, and often results in increased healthcare costs. In order to appropriately treat a patient, knowledge of the different types of pain and various combinations of therapies is imperative. Cryoneurolysis is an important adjunctive therapy in pain management. When used in the appropriate clinical setting, it can decrease a patient's pain, opioid consumption, and improve quality of life. This article reviews common targets for cryoneurolysis based on patient pathology and discusses anatomic considerations to ensure the most efficacious and safe patient outcomes.</p>","PeriodicalId":48689,"journal":{"name":"Seminars in Interventional Radiology","volume":"42 2","pages":"205-212"},"PeriodicalIF":1.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-04-03eCollection Date: 2025-04-01DOI: 10.1055/s-0045-1804908
Mihir Khunte, Fabian Max Laage Gaupp
Prostatic artery embolization (PAE) is a minimally invasive treatment for patients with moderate to severe lower urinary tract symptoms and/or urinary retention due to benign prostatic hyperplasia (BPH), as well as hematuria secondary to prostatic bleeding. PAE achieves its therapeutic effect by inducing ischemic necrosis and reducing prostatic volume, while also decreasing neuromuscular tone. This dual mechanism addresses both the static and dynamic components of bladder outflow obstruction associated with BPH. PAE is technically challenging and necessitates in-depth knowledge of the complex and variable anatomy of the pelvic vasculature. Successful outcomes depend on precise identification of the prostatic artery and recognition of anastomoses to surrounding structures to minimize the risk of nontarget embolization and associated complications. This article reviews the prostatic arterial anatomy and explores the role of advanced imaging techniques for preprocedural planning and intraprocedural guidance to optimize procedural safety and efficacy.
{"title":"Anatomy for Prostatic Artery Embolization.","authors":"Mihir Khunte, Fabian Max Laage Gaupp","doi":"10.1055/s-0045-1804908","DOIUrl":"10.1055/s-0045-1804908","url":null,"abstract":"<p><p>Prostatic artery embolization (PAE) is a minimally invasive treatment for patients with moderate to severe lower urinary tract symptoms and/or urinary retention due to benign prostatic hyperplasia (BPH), as well as hematuria secondary to prostatic bleeding. PAE achieves its therapeutic effect by inducing ischemic necrosis and reducing prostatic volume, while also decreasing neuromuscular tone. This dual mechanism addresses both the static and dynamic components of bladder outflow obstruction associated with BPH. PAE is technically challenging and necessitates in-depth knowledge of the complex and variable anatomy of the pelvic vasculature. Successful outcomes depend on precise identification of the prostatic artery and recognition of anastomoses to surrounding structures to minimize the risk of nontarget embolization and associated complications. This article reviews the prostatic arterial anatomy and explores the role of advanced imaging techniques for preprocedural planning and intraprocedural guidance to optimize procedural safety and efficacy.</p>","PeriodicalId":48689,"journal":{"name":"Seminars in Interventional Radiology","volume":"42 2","pages":"213-218"},"PeriodicalIF":1.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-31eCollection Date: 2025-02-01DOI: 10.1055/s-0045-1805046
Ian Ikeda, Robert Kleven, Joshua Cornman-Homonoff
Percutaneous radiologic gastrostomy is indicated for patients who require enteral access for nutritional support, medication administration, and/or decompression. Some patients have comorbidities that increase procedural risk and may require deviation from the conventional approach, such as upper gastrointestinal tract obstruction, ascites, and postsurgical anatomy. In such cases, technical modifications and/or changes to the standard approach may be needed. This review describes several specific scenarios that require special consideration, focusing on clinical management options, risk mitigation techniques, and supportive evidence.
{"title":"Percutaneous Radiologic Gastrostomy Placement in Challenging Clinical Scenarios.","authors":"Ian Ikeda, Robert Kleven, Joshua Cornman-Homonoff","doi":"10.1055/s-0045-1805046","DOIUrl":"10.1055/s-0045-1805046","url":null,"abstract":"<p><p>Percutaneous radiologic gastrostomy is indicated for patients who require enteral access for nutritional support, medication administration, and/or decompression. Some patients have comorbidities that increase procedural risk and may require deviation from the conventional approach, such as upper gastrointestinal tract obstruction, ascites, and postsurgical anatomy. In such cases, technical modifications and/or changes to the standard approach may be needed. This review describes several specific scenarios that require special consideration, focusing on clinical management options, risk mitigation techniques, and supportive evidence.</p>","PeriodicalId":48689,"journal":{"name":"Seminars in Interventional Radiology","volume":"42 1","pages":"17-21"},"PeriodicalIF":1.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058298/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-31eCollection Date: 2025-04-01DOI: 10.1055/s-0045-1804909
Jacob F Leslie, John B Smirniotopoulos
Trauma, particularly pelvic trauma, is a leading cause of morbidity and mortality in the United States, with hemorrhage being the primary cause of death in these trauma patients. In particular, pelvic fractures often result in substantial vascular injuries, requiring rapid diagnosis, and intervention to prevent fatal outcomes. Multiphase computed tomography angiography (CTA) has emerged as the gold standard for assessing pelvic trauma, facilitating early identification of vascular injuries and active hemorrhage. Interventional radiology (IR) plays a key role in managing these injuries through angiography and embolization, effectively stabilizing hemodynamics and preventing long-term complications such as necrosis or claudication. The complex vascular anatomy of the pelvis, including variants like the corona mortis and aberrant obturator arteries, necessitates careful planning during angiography. Techniques such as nonselective embolization, selective embolization with temporary embolic, and coil embolization are critical in achieving hemostasis. While effective, these procedures carry risks, including rebleeding and complications such as neuropathy and gluteal necrosis. Early activation of the angiography suite and multiphase CTA are essential to improving patient outcomes. This review outlines the anatomy, evaluation, and management strategies for pelvic trauma, emphasizing the importance of rapid intervention and the integral role of IR in controlling hemorrhage and ensuring patient survival.
{"title":"Pelvic Trauma: Anatomy and Interventions.","authors":"Jacob F Leslie, John B Smirniotopoulos","doi":"10.1055/s-0045-1804909","DOIUrl":"10.1055/s-0045-1804909","url":null,"abstract":"<p><p>Trauma, particularly pelvic trauma, is a leading cause of morbidity and mortality in the United States, with hemorrhage being the primary cause of death in these trauma patients. In particular, pelvic fractures often result in substantial vascular injuries, requiring rapid diagnosis, and intervention to prevent fatal outcomes. Multiphase computed tomography angiography (CTA) has emerged as the gold standard for assessing pelvic trauma, facilitating early identification of vascular injuries and active hemorrhage. Interventional radiology (IR) plays a key role in managing these injuries through angiography and embolization, effectively stabilizing hemodynamics and preventing long-term complications such as necrosis or claudication. The complex vascular anatomy of the pelvis, including variants like the corona mortis and aberrant obturator arteries, necessitates careful planning during angiography. Techniques such as nonselective embolization, selective embolization with temporary embolic, and coil embolization are critical in achieving hemostasis. While effective, these procedures carry risks, including rebleeding and complications such as neuropathy and gluteal necrosis. Early activation of the angiography suite and multiphase CTA are essential to improving patient outcomes. This review outlines the anatomy, evaluation, and management strategies for pelvic trauma, emphasizing the importance of rapid intervention and the integral role of IR in controlling hemorrhage and ensuring patient survival.</p>","PeriodicalId":48689,"journal":{"name":"Seminars in Interventional Radiology","volume":"42 2","pages":"139-143"},"PeriodicalIF":1.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-31eCollection Date: 2025-02-01DOI: 10.1055/s-0045-1806797
Robert Kleven, Ian Ikeda, Joshua Cornman-Homonoff
Gastrostomy tubes are a common procedure for interventional radiologists. Several techniques are available to obtain gastric access radiologically, including the antegrade, retrograde, and balloon-assisted techniques. The choice of technique can depend on the patient's clinical presentation and the available services at each institution. Indications, preprocedural workup, technique, and postprocedural care help guide the choice of approach. Three common methods will be reviewed in this article: antegrade, retrograde, and balloon assisted. The antegrade technique is comparable to percutaneous endoscopic gastrostomy placement with a decreased incidence of tube dislodgement compared to the retrograde technique, but it requires reliable oral and esophageal access. The retrograde technique reduces the risk of postprocedural infection, has shorter procedure times, and reduces radiation exposure. The balloon-assisted technique reduces procedure time even more than the antegrade or retrograde technique, with comparable outcomes. Understanding the most common techniques available and how they compare is essential to providing patient-centered care.
{"title":"Percutaneous Radiologic Gastrostomy Tube Placement Techniques.","authors":"Robert Kleven, Ian Ikeda, Joshua Cornman-Homonoff","doi":"10.1055/s-0045-1806797","DOIUrl":"10.1055/s-0045-1806797","url":null,"abstract":"<p><p>Gastrostomy tubes are a common procedure for interventional radiologists. Several techniques are available to obtain gastric access radiologically, including the antegrade, retrograde, and balloon-assisted techniques. The choice of technique can depend on the patient's clinical presentation and the available services at each institution. Indications, preprocedural workup, technique, and postprocedural care help guide the choice of approach. Three common methods will be reviewed in this article: antegrade, retrograde, and balloon assisted. The antegrade technique is comparable to percutaneous endoscopic gastrostomy placement with a decreased incidence of tube dislodgement compared to the retrograde technique, but it requires reliable oral and esophageal access. The retrograde technique reduces the risk of postprocedural infection, has shorter procedure times, and reduces radiation exposure. The balloon-assisted technique reduces procedure time even more than the antegrade or retrograde technique, with comparable outcomes. Understanding the most common techniques available and how they compare is essential to providing patient-centered care.</p>","PeriodicalId":48689,"journal":{"name":"Seminars in Interventional Radiology","volume":"42 1","pages":"9-16"},"PeriodicalIF":1.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-31eCollection Date: 2025-04-01DOI: 10.1055/s-0045-1806854
Daryl Goldman, Brandon D Philbrick, Amol Mehta, Alex Devarajan, Brian Giovanni, Michael Travis Caton
Transarterial embolization of external carotid artery (ECA) branches is increasingly performed for the management of epistaxis, preoperative embolization of head and neck tumors, treatment of dural arteriovenous fistulas, and, more recently, for the treatment of chronic subdural hematoma. As new indications for ECA embolization in the management of conditions like chronic subdural hematoma continue to be identified, it is imperative that interventionalists understand the presence of intricate anastomoses between the extracranial and intracranial arterial systems, which confer significant procedural risks. Failure to account for these connections can result in devastating complications such as stroke, blindness, or cranial nerve injury due to nontarget embolization. This review examines the key anatomical territories of ECA-internal carotid artery anastomoses: the orbital region, petrous-cavernous region, and upper cervical region. These areas, often involving embryological remnants or collateral channels that enlarge in response to pathology, represent potential conduits for inadvertent embolization. We discuss the importance of preprocedural angiography to document anastomosis locations, embolic material selection, special considerations in the context of pathology, and techniques to mitigate risks. Specific considerations for each anatomical region are discussed, with a focus on critical anastomoses, embolization risks, and prevention strategies.
{"title":"Critical Procedural Anatomy of High-Risk External Carotid Artery-Internal Carotid Artery Anastomoses.","authors":"Daryl Goldman, Brandon D Philbrick, Amol Mehta, Alex Devarajan, Brian Giovanni, Michael Travis Caton","doi":"10.1055/s-0045-1806854","DOIUrl":"10.1055/s-0045-1806854","url":null,"abstract":"<p><p>Transarterial embolization of external carotid artery (ECA) branches is increasingly performed for the management of epistaxis, preoperative embolization of head and neck tumors, treatment of dural arteriovenous fistulas, and, more recently, for the treatment of chronic subdural hematoma. As new indications for ECA embolization in the management of conditions like chronic subdural hematoma continue to be identified, it is imperative that interventionalists understand the presence of intricate anastomoses between the extracranial and intracranial arterial systems, which confer significant procedural risks. Failure to account for these connections can result in devastating complications such as stroke, blindness, or cranial nerve injury due to nontarget embolization. This review examines the key anatomical territories of ECA-internal carotid artery anastomoses: the orbital region, petrous-cavernous region, and upper cervical region. These areas, often involving embryological remnants or collateral channels that enlarge in response to pathology, represent potential conduits for inadvertent embolization. We discuss the importance of preprocedural angiography to document anastomosis locations, embolic material selection, special considerations in the context of pathology, and techniques to mitigate risks. Specific considerations for each anatomical region are discussed, with a focus on critical anastomoses, embolization risks, and prevention strategies.</p>","PeriodicalId":48689,"journal":{"name":"Seminars in Interventional Radiology","volume":"42 2","pages":"190-195"},"PeriodicalIF":1.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-28eCollection Date: 2025-08-01DOI: 10.1055/s-0045-1806798
Salvatore J A Sclafani
The Trauma Radiology Service (TRS) at Kings County Hospital was founded in 1976 and immediately integrated into its trauma surgical service (TSS), one of the earliest trauma centers in the United States. For more than 35 years, the TRS introduced surgeons to many applications of advanced diagnostic imaging and interventional procedures that can be used in the care of the injured. Some of these are now standards of practice throughout the world. Arterial embolizations of critical vessels to the brain and viscera, the peripheral and central vasculature, and nonvascular procedures for complications of trauma were described, and indications and techniques were shared through key publications. An understanding of Dr. Ludwik Fleck's epistemology, with thought collectives, thought styles, and collective moods, helps explain the successful integration of interventional radiology in the trauma center.
{"title":"The Origins of Interventional Radiology as a Treatment of the Trauma Patient: A Personal Perspective.","authors":"Salvatore J A Sclafani","doi":"10.1055/s-0045-1806798","DOIUrl":"https://doi.org/10.1055/s-0045-1806798","url":null,"abstract":"<p><p>The Trauma Radiology Service (TRS) at Kings County Hospital was founded in 1976 and immediately integrated into its trauma surgical service (TSS), one of the earliest trauma centers in the United States. For more than 35 years, the TRS introduced surgeons to many applications of advanced diagnostic imaging and interventional procedures that can be used in the care of the injured. Some of these are now standards of practice throughout the world. Arterial embolizations of critical vessels to the brain and viscera, the peripheral and central vasculature, and nonvascular procedures for complications of trauma were described, and indications and techniques were shared through key publications. An understanding of Dr. Ludwik Fleck's epistemology, with thought collectives, thought styles, and collective moods, helps explain the successful integration of interventional radiology in the trauma center.</p>","PeriodicalId":48689,"journal":{"name":"Seminars in Interventional Radiology","volume":"42 4","pages":"390-400"},"PeriodicalIF":1.3,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12614750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145543464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-27eCollection Date: 2025-02-01DOI: 10.1055/s-0045-1806738
Sonia J Giyanani, Marianne E Bonanno, Derek Tang, Robert C Ward
{"title":"Imaging in Interventional Radiology: Breast Cryoablation.","authors":"Sonia J Giyanani, Marianne E Bonanno, Derek Tang, Robert C Ward","doi":"10.1055/s-0045-1806738","DOIUrl":"10.1055/s-0045-1806738","url":null,"abstract":"","PeriodicalId":48689,"journal":{"name":"Seminars in Interventional Radiology","volume":"42 1","pages":"101-113"},"PeriodicalIF":1.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-26eCollection Date: 2025-04-01DOI: 10.1055/s-0045-1806737
Colin Brown, Jonathan Du, Erika Yee, Lisa Kang
{"title":"Nontargeted Liver Biopsy in Children.","authors":"Colin Brown, Jonathan Du, Erika Yee, Lisa Kang","doi":"10.1055/s-0045-1806737","DOIUrl":"10.1055/s-0045-1806737","url":null,"abstract":"","PeriodicalId":48689,"journal":{"name":"Seminars in Interventional Radiology","volume":"42 2","pages":"244-250"},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144081466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-10eCollection Date: 2024-12-01DOI: 10.1055/s-0045-1804998
Momodou L Jammeh, Michael Rabaza, Parag J Patel
Ruptured abdominal aortic aneurysm are a critical vascular emergency. A coordinated, multidisciplinary management pathway can aid in timely diagnosis, triage, and coordination of best care. We present our institutional care algorithm for rAAA with an accompanying case example.
{"title":"Multidisciplinary Management of Aortic Emergencies: Ruptured Abdominal Aortic Aneurysms.","authors":"Momodou L Jammeh, Michael Rabaza, Parag J Patel","doi":"10.1055/s-0045-1804998","DOIUrl":"10.1055/s-0045-1804998","url":null,"abstract":"<p><p>Ruptured abdominal aortic aneurysm are a critical vascular emergency. A coordinated, multidisciplinary management pathway can aid in timely diagnosis, triage, and coordination of best care. We present our institutional care algorithm for rAAA with an accompanying case example.</p>","PeriodicalId":48689,"journal":{"name":"Seminars in Interventional Radiology","volume":"41 6","pages":"531-535"},"PeriodicalIF":1.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}