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Responsiveness and minimal important changes of a Persian version of Lymphedema Life Impact Scale, Upper Limb Functional Index, and Quick Disability of the Arm, Shoulder, and Hand in breast cancer-related lymphedema following physiotherapy. 波斯版淋巴水肿生活影响量表、上肢功能指数和手臂、肩部和手部在物理治疗后的反应性和最小重要变化
IF 1.5 4区 医学 Q2 REHABILITATION Pub Date : 2026-01-23 DOI: 10.1080/09593985.2026.2615402
Shima Eftekhar, Neda Mostafaee, Hossein Negahban, Saeedeh Ebrahimzadeh

Introduction: This study aimed to evaluate responsiveness and minimal important changes (MICs) of a Persian version of the Lymphedema Life Impact Scale (LLIS), the Upper Limb Functional Index (ULFI), and the Quick Disability of the Arm, Shoulder, and Hand (Quick DASH) in patients with breast cancer-related lymphedema (BCRL) following physiotherapy intervention.

Methods: The study included 90 participants with breast cancer-related lymphedema (BCRL) who received a physiotherapy intervention. Participants completed the LLIS, ULFI, and Quick DASH questionnaires at baseline and at a 3-week follow-up. A 7-point global rating of change (GRC) was also administered at the follow-up to serve as an external anchor for improvement. Responsiveness was assessed using correlation analysis and receiver operating characteristic (ROC) curve analysis with patients classified as improved or unimproved based on GRC scores. The ROC curve was utilized to identify the optimal cutoff value as MIC.

Results: All three instruments of the LLIS, ULFI, and Quick DASH demonstrated acceptable responsiveness with the area under the curve of 0.84 (95%CI: 0.76-0.92), 0.85 (95%CI: 0.77-0.93), and 0.90 (95%CI: 0.84-0.96), respectively. Correlation analysis showed relationship of the LLIS, ULFI, and Quick DASH with the external anchor fell within moderate to good range (Spearman = 0.55-0.69). The MIC values for the LLIS, ULFI, and Quick DASH were 10.85, 9.5, and 13.05 points, respectively.

Conclusions: The LLIS, ULFI, and Quick DASH demonstrated adequate responsiveness and effectively measured the change in lymphedema, upper limb function, and disability in BCRL patients undergoing physiotherapy intervention. The MIC values reflecting improvement identified for the LLIS, ULFI, and Quick DASH can help clinicians and researchers to detect meaningful change in an individual's clinical status, and to avoid the challenge of either over- or undervaluing treatment efficacy.

本研究旨在评估波斯语版淋巴水肿生命影响量表(LLIS)、上肢功能指数(ULFI)和手臂、肩部和手部快速残疾(Quick DASH)在乳腺癌相关淋巴水肿(BCRL)患者物理治疗干预后的反应性和最小重要变化(mic)。方法:该研究包括90名接受物理治疗干预的乳腺癌相关淋巴水肿(BCRL)患者。参与者在基线和3周随访时完成了LLIS、ULFI和Quick DASH问卷调查。7分的全球变化评级(GRC)也在随访中作为改善的外部锚点。采用相关性分析和受试者工作特征(ROC)曲线分析评估反应性,根据GRC评分将患者分为改善或未改善。利用ROC曲线确定最佳截止值为MIC。结果:LLIS、ULFI和Quick DASH三种仪器的曲线下面积分别为0.84 (95%CI: 0.76 ~ 0.92)、0.85 (95%CI: 0.77 ~ 0.93)和0.90 (95%CI: 0.84 ~ 0.96),均表现出可接受的反应性。相关分析显示,LLIS、ULFI和Quick DASH与外锚的相关性在中等到良好的范围内(Spearman = 0.55-0.69)。LLIS、ULFI、Quick DASH的MIC值分别为10.85、9.5、13.05分。结论:LLIS、ULFI和Quick DASH在接受物理治疗干预的BCRL患者中表现出足够的反应性,并有效地测量了淋巴水肿、上肢功能和残疾的变化。反映LLIS、ULFI和Quick DASH改善的MIC值可以帮助临床医生和研究人员发现个体临床状态的有意义的变化,并避免高估或低估治疗效果的挑战。
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引用次数: 0
Comparison of voice call based and multimodal telerehabilitation after total knee arthroplasty: a randomized controlled trial. 全膝关节置换术后基于语音呼叫和多模式远程康复的比较:一项随机对照试验。
IF 1.5 4区 医学 Q2 REHABILITATION Pub Date : 2026-01-21 DOI: 10.1080/09593985.2026.2618088
Sema Nur Aslan, Sibel Bozgeyik-Bagdatli, Murat Demirel, Bülent Atilla, Gizem Irem Kinikli

Background: Telerehabilitation has emerged as a promising approach in postoperative care following total knee arthroplasty(TKA);nevertheless,the relative effectiveness of different telerehabilitation modules is still under discussion, leaving room for alternative and multimodal program approaches.

Objectives: This study aimed to compare the effectiveness of a multimodal telerehabilitation(MTR) and voice call based telerehabilitation(VTR) in patients undergoing TKA.

Methods: A two-arm randomized controlled trial was conducted with 24 patients (68.42 ± 9.28y) in the MTR group and 21(71.19 ± 7.26y) in the VTR group. The MTR group received weekly digital booklets containing asynchronous exercise videos, one voice call, one video call,and text messages,for a total of three contacts per week. The VTR group received weekly printed booklets and voice calls three times a week(on alternate days) over the 8-week intervention period. Outcomes were assessed face to face at discharge, and at the 4th and 8th postoperative weeks. Measures included Visual Analog Scale(VAS), active and passive range of motion(ROM), Knee Osteoarthritis Outcome Score-Physical Function(KOOS-PS), Five Repetition Sit to Stand Test(5xSST), Brief Fear of Movement(BFoM) Scale, isometric Quadriceps muscle strength, Forgotten Joint Score-12(FJS-12),Exercise Adherence Rating Scale(EARS). The primary outcome was active knee flexion ROM. Statistical significance was set at p < .05; effect sizes (r, W) were reported for the Mann - Whitney U and Wilcoxon tests.

Results: After 8 weeks, a statistically significant difference in pain during activity was observed between the MTR and VTR groups (p < .001, r = 0.62). Both groups showed significant gains in active and passive knee flexion ROM, 5xSST, and KOOS-PS scores (all p < .001), while the MTR group also improved in rest pain, knee extension, and BFoM (all p < .001). At week 8, statistically significant differences were observed between the MTR and VTR groups across all outcome measures (all p < .001).

Conclusion: Both telerehabilitation approaches were effective in improving pain, ROM, and functional outcomes after TKA.Although this study did not compare outcomes with conventional in-person rehabilitation, MTR showed greater overall improvements than VTR. Nevertheless, VTR remains a reasonable alternative when MTR cannot be implemented.

背景:远程康复已经成为全膝关节置换术(TKA)术后护理的一种很有前途的方法;然而,不同的远程康复模块的相对有效性仍在讨论中,为替代和多模式方案方法留下了空间。目的:本研究旨在比较多模式远程康复(MTR)和基于语音呼叫的远程康复(VTR)在TKA患者中的效果。方法:采用两组随机对照试验,MTR组24例(68.42±9.28y), VTR组21例(71.19±7.26y)。MTR组每周收到包含异步运动视频、一次语音通话、一次视频通话和短信的数字小册子,每周共三次联系。在为期8周的干预期内,VTR组每周收到印刷小册子和语音电话,每周三次(隔天)。出院时、术后第4周和第8周面对面评估结果。测量包括视觉模拟量表(VAS)、主动和被动活动范围(ROM)、膝关节骨性关节炎结局评分-物理功能(KOOS-PS)、五次重复坐立测试(5xSST)、短暂运动恐惧(bom)量表、四头肌力量、遗忘关节评分-12(FJS-12)、运动依从性评定量表(EARS)。结果:8周后,MTR组和VTR组在活动时疼痛的差异有统计学意义(p r = 0.62)。两组在主动和被动膝关节屈曲ROM、5xSST和KOOS-PS评分方面均有显著提高(均为pp)。结论:两种远程康复方法均可有效改善TKA后的疼痛、ROM和功能结局。虽然这项研究没有比较传统的面对面康复的结果,但MTR显示出比VTR更大的总体改善。然而,当港铁无法实施时,VTR仍是一个合理的选择。
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引用次数: 0
Does ankle support orthosis and kinesio tape affect evertor muscles strength and their ability to control force signal in chronic ankle instability? A randomized controlled trial. 踝关节支撑矫形器和运动贴会影响慢性踝关节不稳定患者的动肌力量及其控制力信号的能力吗?一项随机对照试验。
IF 1.5 4区 医学 Q2 REHABILITATION Pub Date : 2026-01-21 DOI: 10.1080/09593985.2026.2615382
Nastaran Ghahremanpour-Khotbehsara, Alireza Farsi, Maryam Jalali, Mohammad Yousefi, Fatemeh Azadinia

Background: Ankle musculature serves as active dynamic stabilizers, yet conventional assessment focusing solely on peak torque fails to capture critical aspects of neuromuscular control. The ability to generate accurate, steady forces is paramount for functional joint stability. External supports may modulate sensorimotor function, potentially improving force control.

Objective: To compare the effectiveness of bracing and taping on the quantity and quality of evertor muscle force.

Methods: Sixty participants (18-40 years old) with chronic ankle instability, were randomly allocated to 3 groups: ankle orthosis, kinesio tape, and a control group. Evertor muscle strength, force sense, force steadiness, and kinesiophobia were evaluated at the baseline and at the end of week 4.

Results: The group × time interaction effects were significant for concentric evertor strength at both angular velocities of 60°/s and 120°/s. While orthosis group and kinesio tape group demonstrated significant within-group changes, there was no difference between the two intervention groups (p = .771; dppc2 = -0.17 at angular velocity of 60°/s, and at angular velocity of 120 °/s p = .930; dppc2 = 0.35), between orthosis group and control group (p = .883; dppc2 = 0.76 at angular velocity 60°/s, and p = .800; dppc2 = 0.71 at angular velocity 120°/s), or between kinesio tape group and control group (p = .975; dppc2 = 1.08, and p = .959; dppc2 = 0.39 at 60°/s, and 120°/s respectively). The group × time interaction effect was also significant for kinesiophobia, but there was no significant difference between the two intervention groups, between orthosis group and control group, and between kinesio tape group and control group. The main effects of time were significant for all variables, except for force sense.

Conclusion: Both ankle orthosis and kinesio tape application for four weeks significantly improved evertor muscle strength and reduced kinesiophobia, with notable trends toward improved force steadiness. These findings support their use as effective interventions for enhancing ankle neuromuscular function and mitigating fear of movement.

背景:踝关节肌肉作为主动的动态稳定器,然而传统的评估仅仅关注峰值扭矩未能捕捉到神经肌肉控制的关键方面。产生准确、稳定的力的能力对于功能性关节的稳定性至关重要。外部支撑可以调节感觉运动功能,潜在地改善力控制。目的:比较支具与贴带对外展肌力数量和质量的影响。方法:慢性踝关节不稳患者60例(18-40岁),随机分为3组:踝关节矫形器组、运动肌贴组和对照组。在基线和第4周结束时评估Evertor肌力、力感、力稳定性和运动恐惧症。结果:在角速度为60°/s和120°/s时,同心圆旋转强度组×时间交互效应显著。同时矫正法组和kinesio带组展示了重要的类内变化,两干预组之间没有差别(p = .771; dppc2 = -0.17的角速度60°/ s,和角速度为120°/ s p = .930; dppc2 = 0.35),矫正法组和对照组之间(p = .883; dppc2角速度60°/ s = 0.76, p = .800; dppc2角速度120°/ s = 0.71),或kinesio带组和对照组之间(p = .975;Dppc2 = 1.08, p = 0.959;Dppc2 = 0.39,分别为60°/s和120°/s)。运动恐惧症的组×时间交互作用也有显著性,但干预组与干预组、矫形器组与对照组、运动胶带组与对照组之间无显著性差异。除力感外,时间对所有变量的主要影响均显著。结论:踝关节矫形器和运动肌贴应用四周后,均能显著改善动肌力量,减少运动恐惧症,并有明显的改善力量稳定性的趋势。这些发现支持它们作为增强踝关节神经肌肉功能和减轻运动恐惧的有效干预措施。
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引用次数: 0
Effectiveness of the Spencer technique on pain, disability and range of motion in patients with frozen shoulder: A systematic review and meta-analysis with meta-regression of randomized controlled trials. Spencer技术对肩周炎患者疼痛、残疾和活动范围的疗效:随机对照试验的系统回顾和荟萃分析。
IF 1.5 4区 医学 Q2 REHABILITATION Pub Date : 2026-01-15 DOI: 10.1080/09593985.2026.2615392
Yu-Ya Tsai, Yu-Jhen Chen, Long-Huei Lin

Introduction: Frozen shoulder (FS) is a disabling condition marked by pain and restricted mobility. The Spencer technique is a structured manual therapy protocol that has been used in clinical practice. However, evidence regarding its effectiveness remains inconsistent. This study systematically evaluated its effects on pain, disability, shoulder range of motion, and potential moderating factors.

Methods: Following PRISMA 2020 guidelines, a comprehensive search of PubMed, Physiotherapy Evidence Database (PEDro), and Medline-Ovid was conducted up to September 2025. Sixteen randomized controlled trials involving 659 participants were included. Outcomes assessed were pain, disability, and shoulder range of motion (external rotation [ER], abduction [ABD], internal rotation [IR]). Random-effects meta-analysis, subgroup, sensitivity, and meta-regression analyses were performed.

Results: The Spencer technique demonstrated positive effects compared with conventional physical therapies (CPTs) in reducing pain, improving disability, and range of motion, including ER, ABD, and IR. However, it did not show superiority over other manual therapies. Meta-regression identified the addition of muscle energy technique as a significant moderator associated with greater improvements in pain intensity (β =  -2.095, p = .012), disability (β =  -1.623, p = .001), and range of motion, including ER (β = 3.878, p < .001), ABD (β = 3.686, p < .001), and IR (β = 1.941, p = .009).

Conclusion: The Spencer technique provides clinical benefits compared with CPTs. However, it does not demonstrate significant superiority over other manual therapy approaches in patients with FS. Incorporation of muscle energy technique enhances its therapeutic effects. Future trials with long-term follow-up and stage-specific analyses are warranted to clarify treatment durability or optimize clinical application.

简介:肩周炎(FS)是一种以疼痛和活动受限为特征的致残疾病。斯宾塞技术是一种结构化的手工治疗方案,已在临床实践中使用。然而,关于其有效性的证据仍然不一致。本研究系统地评估了其对疼痛、残疾、肩部活动范围和潜在调节因素的影响。方法:根据PRISMA 2020指南,综合检索PubMed、物理治疗证据数据库(PEDro)和Medline-Ovid,直至2025年9月。纳入16项随机对照试验,涉及659名受试者。评估的结果是疼痛、残疾和肩关节活动度(外旋[ER]、外展[ABD]、内旋[IR])。进行随机效应meta分析、亚组分析、敏感性分析和meta回归分析。结果:与传统物理疗法(CPTs)相比,Spencer技术在减轻疼痛、改善残疾和活动范围(包括ER、ABD和IR)方面显示出积极的效果。然而,它并没有表现出优于其他手工疗法的优势。meta回归发现,肌肉能量技术的加入与疼痛强度的显著改善相关(β = -2.095, p =)。012),残疾(β = -1.623, p =。001年),和延展性,包括ER(β= 3.878,pβ= 3.686,pβ= 1.941,p = .009)。结论:与CPTs相比,Spencer技术具有临床优势。然而,在FS患者中,它并没有表现出明显优于其他手工治疗方法的优势。肌能技术的结合提高了其治疗效果。未来有必要进行长期随访和具体阶段分析的试验,以阐明治疗的持久性或优化临床应用。
{"title":"Effectiveness of the Spencer technique on pain, disability and range of motion in patients with frozen shoulder: A systematic review and meta-analysis with meta-regression of randomized controlled trials.","authors":"Yu-Ya Tsai, Yu-Jhen Chen, Long-Huei Lin","doi":"10.1080/09593985.2026.2615392","DOIUrl":"https://doi.org/10.1080/09593985.2026.2615392","url":null,"abstract":"<p><strong>Introduction: </strong>Frozen shoulder (FS) is a disabling condition marked by pain and restricted mobility. The Spencer technique is a structured manual therapy protocol that has been used in clinical practice. However, evidence regarding its effectiveness remains inconsistent. This study systematically evaluated its effects on pain, disability, shoulder range of motion, and potential moderating factors.</p><p><strong>Methods: </strong>Following PRISMA 2020 guidelines, a comprehensive search of PubMed, Physiotherapy Evidence Database (PEDro), and Medline-Ovid was conducted up to September 2025. Sixteen randomized controlled trials involving 659 participants were included. Outcomes assessed were pain, disability, and shoulder range of motion (external rotation [ER], abduction [ABD], internal rotation [IR]). Random-effects meta-analysis, subgroup, sensitivity, and meta-regression analyses were performed.</p><p><strong>Results: </strong>The Spencer technique demonstrated positive effects compared with conventional physical therapies (CPTs) in reducing pain, improving disability, and range of motion, including ER, ABD, and IR. However, it did not show superiority over other manual therapies. Meta-regression identified the addition of muscle energy technique as a significant moderator associated with greater improvements in pain intensity (<i>β</i> =  -2.095, <i>p</i> = .012), disability (<i>β</i> =  -1.623, <i>p</i> = .001), and range of motion, including ER (<i>β</i> = 3.878, <i>p</i> < .001), ABD (<i>β</i> = 3.686, <i>p</i> < .001), and IR (<i>β</i> = 1.941, <i>p</i> = .009).</p><p><strong>Conclusion: </strong>The Spencer technique provides clinical benefits compared with CPTs. However, it does not demonstrate significant superiority over other manual therapy approaches in patients with FS. Incorporation of muscle energy technique enhances its therapeutic effects. Future trials with long-term follow-up and stage-specific analyses are warranted to clarify treatment durability or optimize clinical application.</p>","PeriodicalId":48699,"journal":{"name":"Physiotherapy Theory and Practice","volume":" ","pages":"1-17"},"PeriodicalIF":1.5,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145991478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the role of experiential learning in shaping physical therapy student self-efficacy for neurologic practice: A mixed methods study. 探索体验式学习在塑造神经内科物理治疗学生自我效能感中的作用:一项混合方法研究。
IF 1.5 4区 医学 Q2 REHABILITATION Pub Date : 2026-01-15 DOI: 10.1080/09593985.2026.2615385
Martha D Cullaty, Jenny Hall, David Halpin, Lisa Allison-Jones

Introduction: Self-efficacy, one's confidence in performing specific tasks, is a theoretically grounded construct integral to learner motivation, engagement, and perceived readiness for clinical practice. As the prevalence of individuals with neurologic conditions increases, it is essential that physical therapy students develop the confidence and competence needed to meet the complex needs of this population.

Objective: The purpose of this study was to examine how participation in a structured experiential learning program with individuals with neurologic conditions influenced physical therapy students' self-efficacy for neurologic practice.

Methods: A sequential-explanatory mixed methods design was used across three academic semesters with second-year DPT students (n = 32). Quantitative data were first collected via the Physiotherapy Self-Efficacy neurologic subscale, and a 2 × 3 repeated measures ANOVA assessed changes over time and across semesters. Qualitative narrative reflections were then thematically analyzed using deductive and inductive coding to contextualize the quantitative findings.

Results: Twenty-eight students completed the study; three students did not complete all instruments, and one student withdrew from the program. Students' self-efficacy significantly improved over time (F(1, 27) = 131.14, p < .001), by semester (F(1, 38) = 71.60, p < .001), and with a time-by-semester interaction (F(1, 40) = 8.12, p = .003). Four themes helped explain these increases in self-efficacy: concrete experiences, developing confidence for practice, social modeling, and emerging professional identity.

Conclusion: Structured experiential learning with neurologic populations was associated with significant increases in physical therapy students' self-efficacy for neurologic clinical practice. Findings highlight its value in fostering student confidence, professional identity, and task-specific competence. Future research should examine these outcomes across diverse programs.

自我效能感,一个人在执行特定任务时的信心,是一个理论基础的结构,是学习者动机、参与和临床实践感知准备的组成部分。随着患有神经系统疾病的个体的患病率增加,物理治疗学生培养满足这一人群复杂需求所需的信心和能力是至关重要的。目的:本研究的目的是探讨参与神经系统疾病个体的结构化体验学习计划如何影响物理治疗学生在神经系统实践中的自我效能感。方法:采用顺序解释混合方法设计,对DPT二年级学生(n = 32)进行了三个学期的研究。定量数据首先通过物理治疗自我效能神经量表收集,并采用2 × 3重复测量方差分析评估随时间和学期的变化。然后使用演绎和归纳编码对定性叙事反射进行主题分析,以将定量结果置于语境中。结果:28名学生完成研究;三名学生没有完成所有的乐器,一名学生退出了这个项目。学生自我效能感随时间显著提高(F(1,27) = 131.14, p p p = 0.003)。四个主题有助于解释这些自我效能感的增加:具体的经历,培养实践的信心,社会榜样和新兴的职业身份。结论:神经内科人群的结构化体验式学习与物理治疗学生神经内科临床实践自我效能感的显著提高有关。研究结果强调了它在培养学生信心、职业认同和特定任务能力方面的价值。未来的研究应该在不同的项目中检验这些结果。
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引用次数: 0
Investigating acute care physical therapy in general medicine: a retrospective analysis of utilization and effectiveness. 调查急诊物理治疗在普通医学:回顾性分析的利用和有效性。
IF 1.5 4区 医学 Q2 REHABILITATION Pub Date : 2026-01-13 DOI: 10.1080/09593985.2025.2609880
James P Crick, Gabriel N Alain, Cristiane Meirelles, Marka Gehrig, Lisa Juckett, Carmen Quatman, Catherine Quatman-Yates

Background: Physical therapy (PT) has been associated with improved patient- and system- outcomes for hospitalized patients. However, significant variation exists in PT delivery to general medicine patients, and there has been little research exploring the utilization and effectiveness of PT in this population.

Purpose: The purpose of this study is to investigate the utilization and effectiveness of PT for acutely hospitalized general medicine patients, focusing on the relationship between PT minutes per day provided and patient functional improvement and discharge disposition.

Methods: This retrospective observational cohort study analyzed clinical data from 7693 patients admitted to an urban academic medical center between July 2021 and December 2023. Patients included were at least 18 years old, discharged alive, and received at least two PT visits. The primary predictor variable was minutes per day of PT provided. The primary outcome was functional improvement, measured by the Activity Measure for Post-Acute Care (AM-PAC) Basic Mobility "six-clicks" score. The secondary outcome was discharge to home. Multivariable logistic regression models were used to estimate adjusted odds ratios (aOR) for functional improvement and discharge disposition.

Results: Each 10-minute increase in PT minutes per day provided positively associated with functional improvement (aOR = 1.16 per 10-minute increase, 95% CI 1.07-1.25, p < .0001) and discharge to home (aOR = 1.22 per 10-minute increase, 95% CI 1.13-1.31, p < .0001). Higher daily PT thresholds showed increasing adjusted probabilities of functional improvement and discharge home, though gains in functional improvement plateaued beyond 30 minutes per day.

Conclusion: Increased daily PT was associated with greater functional improvement and higher likelihood of discharge to home. These results support more intentional PT resource allocation and suggest that identifying clinically meaningful treatment thresholds may help guide therapist decision-making.

背景:物理治疗(PT)与住院患者患者和系统预后的改善有关。然而,在普通医学患者中,PT的给药情况存在显著差异,并且很少有研究探讨PT在这一人群中的利用和有效性。目的:本研究的目的是探讨急性住院全科患者PT的使用和有效性,重点研究每日提供PT分钟数与患者功能改善和出院处置的关系。方法:本回顾性观察队列研究分析了2021年7月至2023年12月在某城市学术医疗中心就诊的7693例患者的临床资料。纳入的患者至少18岁,活着出院,并接受了至少两次PT访问。主要预测变量是每天提供的PT分钟数。主要结果是功能改善,通过急性护理后活动测量(AM-PAC)基本活动能力“六点击”评分来衡量。次要结果是出院回家。多变量logistic回归模型用于估计功能改善和出院处置的调整优势比(aOR)。结果:每天每增加10分钟的PT时间与功能改善呈正相关(aOR = 1.16 / 10分钟增加,95% CI 1.07-1.25, p p)。结论:每天增加PT时间与更大的功能改善和更大的出院可能性相关。这些结果支持更有意识的PT资源分配,并表明确定临床有意义的治疗阈值可能有助于指导治疗师决策。
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引用次数: 0
Functional immersive rehabilitation for a severely burned patient with refractory pain: A case report. 重度烧伤患者难治性疼痛的沉浸式功能康复1例报告。
IF 1.5 4区 医学 Q2 REHABILITATION Pub Date : 2026-01-12 DOI: 10.1080/09593985.2026.2615378
Cristián Lathrop, Carolina Pino, Benjamín Peralta-Wieland

Background: Severe burn injuries often lead to prolonged hospitalization, functional impairments, and painful necessary interventions such as physical and occupational therapy. Pharmacological pain management is often insufficient and associated with adverse effects, highlighting the need for integrative strategies that combine pain modulation with functional rehabilitation.

Objective: To evaluate the feasibility and impact of immersive virtual reality (VR) rehabilitation for pain modulation, functional recovery, and health economics in a severely burned patient.

Case description: A 24-year-old firefighter sustained burns over 60% of total body surface area resulting in refractory pain and requiring prolonged intensive care unit stay. A rehabilitation protocol combining immersive motor training with conventional therapy was implemented, consisting of 12 sessions using a VR system designed to modulate pain and enhance motor engagement. Outcomes included Numerical Rating Scale (NRS) for pain, VR experience, Functional Independence Measure (FIM), User Satisfaction Evaluation Questionnaire (USEQ), and medication costs.

Outcomes: Procedural pain decreased from severe (median NRS: 8/10) to moderate (4/10), with greater immersion correlating with lower pain intensity. Functionally, the patient progressed from full dependence (FIM: 13/91) to assisted ambulation (45/91), reaching improved independence by 8 months (59/91). The intervention was well tolerated (USEQ: 93.33%) with a reduced need for analgesic medication, resulting in a substantial cost savings (overall 59% reduction in total analgesic costs).

Conclusion: Immersive rehabilitation was a feasible, non-pharmacologic strategy that enhanced recovery, reduced pain, and decreased pharmacologic costs for a complex patient recovering from severe burns.

背景:严重的烧伤往往导致长期住院,功能损伤和痛苦的必要干预,如物理和职业治疗。药物疼痛管理往往不足,并伴有不良反应,强调需要将疼痛调节与功能康复相结合的综合策略。目的:评价沉浸式虚拟现实(VR)康复对严重烧伤患者疼痛调节、功能恢复和健康经济学的可行性和影响。病例描述:一名24岁的消防员烧伤面积超过全身表面积的60%,导致难治性疼痛,需要长期住在重症监护室。实施了一项将沉浸式运动训练与传统疗法相结合的康复方案,包括12个会话,使用旨在调节疼痛和增强运动参与的VR系统。结果包括疼痛数值评定量表(NRS)、虚拟现实体验、功能独立性量表(FIM)、用户满意度评估问卷(USEQ)和药物费用。结果:手术疼痛从严重(中位NRS: 8/10)下降到中度(4/10),浸泡程度越深,疼痛强度越低。在功能上,患者从完全依赖(FIM: 13/91)发展到辅助行走(45/91),8个月时达到改善的独立性(59/91)。该干预措施耐受性良好(USEQ: 93.33%),减少了镇痛药物的需求,从而节省了大量成本(总镇痛成本降低了59%)。结论:沉浸式康复是一种可行的非药物治疗策略,对于复杂的严重烧伤患者来说,它能促进康复,减轻疼痛,降低药物费用。
{"title":"Functional immersive rehabilitation for a severely burned patient with refractory pain: A case report.","authors":"Cristián Lathrop, Carolina Pino, Benjamín Peralta-Wieland","doi":"10.1080/09593985.2026.2615378","DOIUrl":"https://doi.org/10.1080/09593985.2026.2615378","url":null,"abstract":"<p><strong>Background: </strong>Severe burn injuries often lead to prolonged hospitalization, functional impairments, and painful necessary interventions such as physical and occupational therapy. Pharmacological pain management is often insufficient and associated with adverse effects, highlighting the need for integrative strategies that combine pain modulation with functional rehabilitation.</p><p><strong>Objective: </strong>To evaluate the feasibility and impact of immersive virtual reality (VR) rehabilitation for pain modulation, functional recovery, and health economics in a severely burned patient.</p><p><strong>Case description: </strong>A 24-year-old firefighter sustained burns over 60% of total body surface area resulting in refractory pain and requiring prolonged intensive care unit stay. A rehabilitation protocol combining immersive motor training with conventional therapy was implemented, consisting of 12 sessions using a VR system designed to modulate pain and enhance motor engagement. Outcomes included Numerical Rating Scale (NRS) for pain, VR experience, Functional Independence Measure (FIM), User Satisfaction Evaluation Questionnaire (USEQ), and medication costs.</p><p><strong>Outcomes: </strong>Procedural pain decreased from severe (median NRS: 8/10) to moderate (4/10), with greater immersion correlating with lower pain intensity. Functionally, the patient progressed from full dependence (FIM: 13/91) to assisted ambulation (45/91), reaching improved independence by 8 months (59/91). The intervention was well tolerated (USEQ: 93.33%) with a reduced need for analgesic medication, resulting in a substantial cost savings (overall 59% reduction in total analgesic costs).</p><p><strong>Conclusion: </strong>Immersive rehabilitation was a feasible, non-pharmacologic strategy that enhanced recovery, reduced pain, and decreased pharmacologic costs for a complex patient recovering from severe burns.</p>","PeriodicalId":48699,"journal":{"name":"Physiotherapy Theory and Practice","volume":" ","pages":"1-8"},"PeriodicalIF":1.5,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of an evidence-based modified developmental physiotherapy intervention on muscle tone, motor functions, and trunk control in a child with hereditary spastic paraplegia type 47: A case report. 循证改良发育物理治疗干预对47型遗传性痉挛性截瘫儿童肌张力、运动功能和躯干控制的影响:1例报告
IF 1.5 4区 医学 Q2 REHABILITATION Pub Date : 2026-01-12 DOI: 10.1080/09593985.2026.2615379
Bayram Sırrı

Background: Most current studies on Hereditary Spastic Paraplegia (HSP) focus on adolescents and adults. There is a lack of research on the effectiveness of structured, evidence-based developmental physiotherapy during early childhood. While early intervention strategies for children with motor development delays offer a useful framework, no specific guidelines have been developed for early physiotherapy in HSP. This report aimed to describe the effects of a home-based, evidence-based developmental physiotherapy approach in a child diagnosed with HSP Type 47 (SPG47).

Case description: A two-year-old child with SPG47 participated with parental consent. Before intervention, the child was unable to stand up using support or take more than a few side steps. Muscle tone, motor function, functional level, and trunk control were assessed using MAS, GMFCS, GMFM-66, and SATCo, respectively.

Interventions: A developmental physiotherapy program based on current evidence was implemented at home for 2 hours daily over 8 weeks, with daily home implementation by the family. The intervention was grounded in family-centered care principles and evidence-based early developmental physiotherapy, tailored to the child's clinical presentation.

Outcomes: After the program, GMFM-66 increased by 7.2%. The child gained the ability to stand independently and take more than five side steps. MAS scores improved, SATCo increased from level 6 to 7, and GMFCS improved from level III to II.

Conclusion: In this child with SPG47, an early structured developmental physiotherapy approach was associated with improved motor function and reduced spasticity, supported by motor learning, environmental adaptations, and family involvement. Integrating early intervention principles with HSP-specific considerations enabled targeted task progression and practical home implementation. These findings apply only to this child, and further research is needed to determine whether similar strategies may benefit children with AP4B1-related HSP.

背景:目前大多数关于遗传性痉挛性截瘫(HSP)的研究集中在青少年和成人。关于结构化的、基于证据的儿童早期发育物理治疗的有效性的研究缺乏。虽然运动发育迟缓儿童的早期干预策略提供了一个有用的框架,但没有针对HSP的早期物理治疗制定具体的指导方针。本报告旨在描述以家庭为基础的循证发育物理治疗方法在诊断为47型HSP (SPG47)的儿童中的效果。病例描述:一名患有SPG47的两岁儿童在父母同意的情况下参与。在干预之前,这个孩子不能用辅助站起来,也不能多走几步。分别使用MAS、GMFCS、GMFM-66和SATCo评估肌肉张力、运动功能、功能水平和躯干控制。干预措施:基于现有证据的发育物理治疗方案在家中实施,每天2小时,持续8周,每天由家庭实施。干预以家庭为中心的护理原则和基于证据的早期发育物理疗法为基础,根据儿童的临床表现量身定制。结果:项目结束后,GMFM-66增加了7.2%。孩子获得了独立站立的能力,并能走五个以上的侧步。MAS评分提高,SATCo从6级提高到7级,GMFCS从III级提高到II级。结论:在该SPG47患儿中,在运动学习、环境适应和家庭参与的支持下,早期结构化发育物理治疗方法与改善运动功能和减少痉挛有关。将早期干预原则与hsp特定考虑相结合,可以实现有针对性的任务进展和实际的家庭实施。这些发现只适用于这名儿童,需要进一步的研究来确定类似的策略是否可以使ap4b1相关的HSP儿童受益。
{"title":"Effect of an evidence-based modified developmental physiotherapy intervention on muscle tone, motor functions, and trunk control in a child with hereditary spastic paraplegia type 47: A case report.","authors":"Bayram Sırrı","doi":"10.1080/09593985.2026.2615379","DOIUrl":"https://doi.org/10.1080/09593985.2026.2615379","url":null,"abstract":"<p><strong>Background: </strong>Most current studies on Hereditary Spastic Paraplegia (HSP) focus on adolescents and adults. There is a lack of research on the effectiveness of structured, evidence-based developmental physiotherapy during early childhood. While early intervention strategies for children with motor development delays offer a useful framework, no specific guidelines have been developed for early physiotherapy in HSP. This report aimed to describe the effects of a home-based, evidence-based developmental physiotherapy approach in a child diagnosed with HSP Type 47 (SPG47).</p><p><strong>Case description: </strong>A two-year-old child with SPG47 participated with parental consent. Before intervention, the child was unable to stand up using support or take more than a few side steps. Muscle tone, motor function, functional level, and trunk control were assessed using MAS, GMFCS, GMFM-66, and SATCo, respectively.</p><p><strong>Interventions: </strong>A developmental physiotherapy program based on current evidence was implemented at home for 2 hours daily over 8 weeks, with daily home implementation by the family. The intervention was grounded in family-centered care principles and evidence-based early developmental physiotherapy, tailored to the child's clinical presentation.</p><p><strong>Outcomes: </strong>After the program, GMFM-66 increased by 7.2%. The child gained the ability to stand independently and take more than five side steps. MAS scores improved, SATCo increased from level 6 to 7, and GMFCS improved from level III to II.</p><p><strong>Conclusion: </strong>In this child with SPG47, an early structured developmental physiotherapy approach was associated with improved motor function and reduced spasticity, supported by motor learning, environmental adaptations, and family involvement. Integrating early intervention principles with HSP-specific considerations enabled targeted task progression and practical home implementation. These findings apply only to this child, and further research is needed to determine whether similar strategies may benefit children with AP4B1-related HSP.</p>","PeriodicalId":48699,"journal":{"name":"Physiotherapy Theory and Practice","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physical therapists' perspectives on a large language model-powered knowledge translation tool for guideline adherence: A qualitative focus group study. 物理治疗师对指南依从性的大型语言模型驱动的知识翻译工具的观点:一项定性焦点小组研究。
IF 1.5 4区 医学 Q2 REHABILITATION Pub Date : 2026-01-06 DOI: 10.1080/09593985.2025.2606058
Diane Rosen, Dorian Zwanzig, Barbara Vogel, Michael Erhart, Nils Lennart Reiter

Background: Clinical practice guidelines support healthcare professionals in making evidence-based decisions, yet guideline adherence among physical therapists remains inconsistent. To address this gap, a prototype digital knowledge translation tool powered by a large language model (LLM) was developed, with content based on two exemplary high-quality German national guidelines.

Objective: To (1) explore the experiences of German physical therapists using the tool, (2) assess their perspectives on its utilization in clinical practice, and (3) compare perceptions between outpatient and inpatient settings.

Methods: Six focus group interviews were conducted: three in a university hospital inpatient setting and three in outpatient physical therapy practices. Discussions were analyzed using qualitative content analysis with inductive and deductive coding.

Results: Twenty physical therapists (11 inpatient, 9 outpatient) participated. Overall experiences were positive, though prolonged response times were criticized. Utilization was thought to depend on time availability and workplace digitization. The tool's potential assisting with clinical questions was highlighted. No considerable differences in experiences across settings were noted. Inpatient therapists envisioned using the tool between sessions for personal knowledge enhancement, whereas outpatient therapists anticipated utilization during sessions for patient education.

Conclusion: LLM-based knowledge translation tools may contribute to improving guideline adherence among physical therapists. Successful implementation requires assessment of digital infrastructure, relevance to clinical needs, and users' digital literacy. Further research should evaluate the quality of LLM-generated summaries to ensure validity and trustworthiness, and optimize the tools' usability regarding speed and content. Development should also prompt ethical considerations about their role in clinical decision-making and patient care.

背景:临床实践指南支持医疗保健专业人员做出基于证据的决策,然而物理治疗师对指南的依从性仍然不一致。为了解决这一差距,开发了一个由大型语言模型(LLM)驱动的原型数字知识翻译工具,其内容基于两个典型的高质量德国国家指南。目的:(1)探索德国物理治疗师使用该工具的经验,(2)评估他们在临床实践中使用该工具的观点,(3)比较门诊和住院设置之间的看法。方法:进行6个焦点小组访谈:3个在大学医院住院,3个在门诊物理治疗实践。采用归纳编码和演绎编码的定性内容分析方法对讨论进行分析。结果:20名物理治疗师(住院11名,门诊9名)参与。总体体验是积极的,尽管长时间的响应时间受到批评。利用率被认为取决于时间可用性和工作场所的数字化。强调了该工具在协助解决临床问题方面的潜力。不同环境下的体验没有显著差异。住院治疗师设想在会议之间使用该工具来提高个人知识,而门诊治疗师则期望在会议期间使用该工具来进行患者教育。结论:基于法学硕士的知识翻译工具可能有助于提高物理治疗师对指南的依从性。成功实施需要评估数字基础设施、与临床需求的相关性以及用户的数字素养。进一步的研究应该评估法学硕士生成的摘要的质量,以确保有效性和可信度,并优化工具在速度和内容方面的可用性。发展还应促使对其在临床决策和患者护理中的作用的伦理考虑。
{"title":"Physical therapists' perspectives on a large language model-powered knowledge translation tool for guideline adherence: A qualitative focus group study.","authors":"Diane Rosen, Dorian Zwanzig, Barbara Vogel, Michael Erhart, Nils Lennart Reiter","doi":"10.1080/09593985.2025.2606058","DOIUrl":"https://doi.org/10.1080/09593985.2025.2606058","url":null,"abstract":"<p><strong>Background: </strong>Clinical practice guidelines support healthcare professionals in making evidence-based decisions, yet guideline adherence among physical therapists remains inconsistent. To address this gap, a prototype digital knowledge translation tool powered by a large language model (LLM) was developed, with content based on two exemplary high-quality German national guidelines.</p><p><strong>Objective: </strong>To (1) explore the experiences of German physical therapists using the tool, (2) assess their perspectives on its utilization in clinical practice, and (3) compare perceptions between outpatient and inpatient settings.</p><p><strong>Methods: </strong>Six focus group interviews were conducted: three in a university hospital inpatient setting and three in outpatient physical therapy practices. Discussions were analyzed using qualitative content analysis with inductive and deductive coding.</p><p><strong>Results: </strong>Twenty physical therapists (11 inpatient, 9 outpatient) participated. Overall experiences were positive, though prolonged response times were criticized. Utilization was thought to depend on time availability and workplace digitization. The tool's potential assisting with clinical questions was highlighted. No considerable differences in experiences across settings were noted. Inpatient therapists envisioned using the tool between sessions for personal knowledge enhancement, whereas outpatient therapists anticipated utilization during sessions for patient education.</p><p><strong>Conclusion: </strong>LLM-based knowledge translation tools may contribute to improving guideline adherence among physical therapists. Successful implementation requires assessment of digital infrastructure, relevance to clinical needs, and users' digital literacy. Further research should evaluate the quality of LLM-generated summaries to ensure validity and trustworthiness, and optimize the tools' usability regarding speed and content. Development should also prompt ethical considerations about their role in clinical decision-making and patient care.</p>","PeriodicalId":48699,"journal":{"name":"Physiotherapy Theory and Practice","volume":" ","pages":"1-14"},"PeriodicalIF":1.5,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sacral osteoblastoma masquerading as sacroiliac joint dysfunction: A case report. 以骶髂关节功能障碍为伪装的骶骨成骨细胞瘤1例。
IF 1.5 4区 医学 Q2 REHABILITATION Pub Date : 2026-01-05 DOI: 10.1080/09593985.2025.2604117
William J Hanney, Morey J Kolber, Abigail W Anderson, William Hanney, Vivek Vemugunta

Background: Lumbosacral pain is a common musculoskeletal complaint that is typically mechanical in nature. However, rare conditions such as osteoblastoma can mimic benign spinal pain, leading to diagnostic delays and protracted care.

Case presentation: An 18-year-old male college student presented to physical therapy, via direct access, with persistent right-sided lumbosacral pain of 6 weeks. His pain worsened with general activity and lying supine. Clinical examination was pathognomonic of sacroiliac (SI) joint dysfunction, and clinical guidelines did not indicate a need for imaging. Four weeks of conservative management for presumed SI joint dysfunction was initiated and included mobilization, stabilization exercises, and use of an SI support belt. Despite adherence to an evidence-based plan of care, the patient failed to demonstrate clinically important improvement in pain and function based on previously established minimal clinically important difference thresholds. The patient ultimately, over the course of care, exhibited intermittent difficulty with bladder voiding and was referred to his family physician and ultimately a surgeon for further evaluation.

Diagnosis: Subsequent magnetic resonance imaging (MRI) and computed tomography (CT) revealed a lobulated, multi-cystic lesion involving the right sacrum extending into the S1 and S2 neural foramina. A CT-guided biopsy confirmed the diagnosis of osteoblastoma with secondary aneurysmal bone cyst features. Intervention: The patient underwent surgical excision of the tumor with decompression of the S1-S2 nerve roots. A multidisciplinary team including orthopedic and neurosurgical specialists performed the procedure without complication.

Outcomes: Postoperative recovery was uneventful, and follow-up MRI at 6 months and 1 year showed no evidence of recurrence. The patient, via telephone communication, reported resolution of symptoms and pre-morbid return to function at the 1-year post-operative period.

Conclusion: This case underscores the importance of considering red flags when patients are recalcitrant to standard interventions. A poor response to conservative care should prompt a referral for imaging.

背景:腰骶痛是一种常见的肌肉骨骼疾病,典型的机械性质。然而,罕见的情况,如成骨细胞瘤可以模拟良性脊柱疼痛,导致诊断延误和长期护理。病例介绍:一名18岁男大学生,因右侧腰骶部持续疼痛6周,经直接入路接受物理治疗。他的疼痛随着一般活动和仰卧而加重。临床检查是骶髂(SI)关节功能障碍的病理特征,临床指南并未表明需要影像学检查。对假定的骶髂关节功能障碍进行为期四周的保守治疗,包括活动、稳定练习和使用骶髂支撑带。尽管患者坚持循证治疗计划,但根据先前建立的最小临床重要差异阈值,患者未能表现出临床上重要的疼痛和功能改善。最终,在治疗过程中,患者表现出间歇性膀胱排尿困难,并被转介给他的家庭医生和外科医生进行进一步评估。诊断:随后的磁共振成像(MRI)和计算机断层扫描(CT)显示一分叶状、多囊性病变累及右侧骶骨,并延伸至S1和S2神经孔。ct引导下的活检证实了成骨细胞瘤伴继发性动脉瘤样骨囊肿的诊断。干预措施:患者行手术切除肿瘤并减压S1-S2神经根。包括骨科和神经外科专家在内的多学科团队进行了手术,无并发症。结果:术后恢复顺利,随访6个月和1年MRI未见复发。患者通过电话交流,报告了术后1年症状的缓解和病前功能的恢复。结论:该病例强调了当患者对标准干预措施不适应时考虑危险信号的重要性。对保守治疗的不良反应应提示转诊影像学检查。
{"title":"Sacral osteoblastoma masquerading as sacroiliac joint dysfunction: A case report.","authors":"William J Hanney, Morey J Kolber, Abigail W Anderson, William Hanney, Vivek Vemugunta","doi":"10.1080/09593985.2025.2604117","DOIUrl":"10.1080/09593985.2025.2604117","url":null,"abstract":"<p><strong>Background: </strong>Lumbosacral pain is a common musculoskeletal complaint that is typically mechanical in nature. However, rare conditions such as osteoblastoma can mimic benign spinal pain, leading to diagnostic delays and protracted care.</p><p><strong>Case presentation: </strong>An 18-year-old male college student presented to physical therapy, via direct access, with persistent right-sided lumbosacral pain of 6 weeks. His pain worsened with general activity and lying supine. Clinical examination was pathognomonic of sacroiliac (SI) joint dysfunction, and clinical guidelines did not indicate a need for imaging. Four weeks of conservative management for presumed SI joint dysfunction was initiated and included mobilization, stabilization exercises, and use of an SI support belt. Despite adherence to an evidence-based plan of care, the patient failed to demonstrate clinically important improvement in pain and function based on previously established minimal clinically important difference thresholds. The patient ultimately, over the course of care, exhibited intermittent difficulty with bladder voiding and was referred to his family physician and ultimately a surgeon for further evaluation.</p><p><strong>Diagnosis: </strong>Subsequent magnetic resonance imaging (MRI) and computed tomography (CT) revealed a lobulated, multi-cystic lesion involving the right sacrum extending into the S1 and S2 neural foramina. A CT-guided biopsy confirmed the diagnosis of osteoblastoma with secondary aneurysmal bone cyst features. Intervention: The patient underwent surgical excision of the tumor with decompression of the S1-S2 nerve roots. A multidisciplinary team including orthopedic and neurosurgical specialists performed the procedure without complication.</p><p><strong>Outcomes: </strong>Postoperative recovery was uneventful, and follow-up MRI at 6 months and 1 year showed no evidence of recurrence. The patient, via telephone communication, reported resolution of symptoms and pre-morbid return to function at the 1-year post-operative period.</p><p><strong>Conclusion: </strong>This case underscores the importance of considering red flags when patients are recalcitrant to standard interventions. A poor response to conservative care should prompt a referral for imaging.</p>","PeriodicalId":48699,"journal":{"name":"Physiotherapy Theory and Practice","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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