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Menopausal hormone therapy: Making sense of current guidelines. 绝经期激素治疗:当前指南的意义。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-07-01 Epub Date: 2025-06-24 DOI: 10.1097/01.JAA.0000000000000226
Ashley Church, Megan Biagi

Abstract: Emerging evidence confirms that menopausal hormone therapy (MHT) remains the most effective treatment for managing vasomotor and genitourinary symptoms of menopause, with a favorable risk-benefit profile in specific patient populations. Recent studies also indicate that initiating MHT in appropriate candidates is associated with reduced cardiovascular disease risk and lower all-cause mortality. This article provides a comprehensive overview of current guidelines for primary care providers, advocating for an evidence-based, patient-centered approach to enhancing menopausal care across diverse patient populations.

摘要:新出现的证据证实,绝经期激素治疗(MHT)仍然是治疗绝经期血管舒缩和泌尿生殖系统症状最有效的治疗方法,在特定患者群体中具有良好的风险-收益特征。最近的研究还表明,在适当的候选者中启动MHT与降低心血管疾病风险和降低全因死亡率相关。本文全面概述了初级保健提供者的现行指南,倡导以证据为基础,以患者为中心的方法来加强不同患者群体的绝经期护理。
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引用次数: 0
If my wounds were visible: The hidden side of intimate partner violence. 如果我的伤口是可见的:亲密伴侣暴力隐藏的一面。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-06-01 Epub Date: 2025-05-27 DOI: 10.1097/01.JAA.0000000000000215
Angela C Meredith
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引用次数: 0
What caused this patient's sunken eye? 是什么导致了这个病人凹陷的眼睛?
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-06-01 Epub Date: 2025-05-27 DOI: 10.1097/01.JAA.0000000000000092
Aujala Mathew, Michelle Lea
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引用次数: 0
Breast cancer screening for patients at higher-than-average risk. 对风险高于平均水平的患者进行乳腺癌筛查。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-06-01 Epub Date: 2025-05-27 DOI: 10.1097/01.JAA.0000000000000213
Vanessa B Mitchell

Abstract: Breast cancer is the most common type of cancer diagnosed in women, excluding skin cancer. It is one of the leading causes of cancer-related deaths and premature deaths in the United States. Given the latest data on breast cancer prevalence, most clinical practice guidelines recommend yearly screening with mammography for women age 40 years and older. However, some women's lifetime risk of breast cancer may be higher than average, requiring additional testing and more intensive screening. Currently, no standard approach to office-based risk assessment has been established in the United States. A woman's unidentified heightened risk can lead to missed opportunities and insufficient screening recommendations. Breast cancer risk assessment is thus critical for identifying women who are at higher-than-average risk for breast cancer and in need of a modified screening plan. This article aims to guide clinicians through assessing a woman's lifetime risk of breast cancer, identifying women at higher-than-average risk, determining which women need to be referred for genetic testing, and managing screening and counseling for patients with nonhereditary higher-than-average risk.

摘要:乳腺癌是女性中除皮肤癌外最常见的癌症类型。它是美国癌症相关死亡和过早死亡的主要原因之一。鉴于有关乳腺癌患病率的最新数据,大多数临床实践指南建议40岁及以上的女性每年进行乳房x光检查。然而,一些女性一生患乳腺癌的风险可能高于平均水平,需要额外的检测和更密集的筛查。目前,美国还没有建立基于办公室的风险评估的标准方法。女性不明的高风险可能导致错过机会和不充分的筛查建议。因此,乳腺癌风险评估对于确定患乳腺癌风险高于平均水平并需要修改筛查计划的妇女至关重要。本文旨在指导临床医生评估女性患乳腺癌的终生风险,确定风险高于平均水平的女性,确定哪些女性需要进行基因检测,并对非遗传性风险高于平均水平的患者进行筛查和咨询。
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引用次数: 0
The expatriate PA. 外籍私人助理。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-06-01 Epub Date: 2025-05-27 DOI: 10.1097/01.JAA.0000000000000214
Roderick S Hooker
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引用次数: 0
Evaluating lymphadenopathy. 评估淋巴结病。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-06-01 Epub Date: 2025-05-27 DOI: 10.1097/01.JAA.0000000000000212
Clay W Walker, Brittney Hulsey, Manuel Pompa

Abstract: Lymphadenopathy (LAD), characterized by abnormal enlargement of lymph nodes, is frequently encountered in clinical practice. Despite its prevalence, the condition's evaluation and management pose significant challenges due to its diverse etiologies, which range from benign conditions to serious malignancies. This article provides a comprehensive overview of LAD, including its etiology, pathophysiology, clinical presentation, and diagnostic evaluation to aid providers, particularly physician associates (PAs), in care of these patients. Through detailed discussions and practical guidance, the article equips PAs with the necessary tools to effectively navigate the complexities of LAD.

摘要/ Abstract摘要:淋巴结病(Lymphadenopathy, LAD)是临床上常见的一种以淋巴结异常肿大为特征的疾病。尽管其发病率很高,但由于其病因多样,从良性疾病到严重恶性疾病,该病的评估和管理面临着重大挑战。本文提供了LAD的全面概述,包括其病因,病理生理学,临床表现和诊断评估,以帮助提供者,特别是医师助理(PAs)照顾这些患者。通过详细的讨论和实践指导,本文为pa提供了必要的工具,以有效地驾驭LAD的复杂性。
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引用次数: 0
A pilot study of PAs in leadership: Exploring pathways, barriers, and support systems. 领导中的pa的初步研究:探索途径、障碍和支持系统。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-06-01 Epub Date: 2025-05-27 DOI: 10.1097/01.JAA.0000000000000109
Marcia Bouton, Robert McKenna, Yolanda Freeman-Hildreth, Theresa Johnson, Ryann Piotrowski, Laura Chenevert

Objectives: The objectives of this study were to determine pathways, barriers, and support systems experienced by physician associates (PAs) in leadership.

Methods: Focus group interviews were conducted with 20 PA leaders. Thematic evaluation revealed inductive themes. Moderate interrater agreement was achieved.

Results: Most participants were female, White, and non-Hispanic, with 13 to 23 years of experience as a PA. Participants obtained leadership positions via training, dedication to service, and networking. Participants were motivated to pursue leadership roles by issues related to compensation, time, and autonomy. Biased perception of PA roles and corporate and legal issues were the most common barriers to achieving leadership positions. Participants recommended that PAs interested in leadership self-promote and that they embrace both altruism and a growth mindset.

Conclusion: PA leaders achieved leadership positions via dedication, networking, and training. Corporate, legal, and perceptual barriers exist. Employers and PA organizations can support PA leaders with training, compensation, protected time, and autonomy. Celebration of the value of PA leadership is needed.

目的:本研究的目的是确定医师助理(PAs)在领导中经历的途径、障碍和支持系统。方法:对20名PA领导进行焦点小组访谈。主题评价揭示归纳主题。取得了适度的判读一致。结果:大多数参与者为女性,白人,非西班牙裔,具有13至23年的私人助理经验。参与者通过培训、奉献服务和网络获得领导职位。参与者被与报酬、时间和自主权相关的问题激励着去追求领导角色。对私人助理角色以及公司和法律问题的偏见是获得领导职位的最常见障碍。参与者建议,对领导力感兴趣的个人助理应该自我推销,并同时拥有利他主义和成长心态。结论:PA领导者通过奉献、网络和培训获得领导地位。公司、法律和认知障碍都存在。雇主和PA组织可以通过培训、补偿、保护时间和自主权来支持PA领导。有必要颂扬巴勒斯坦权力机构的领导价值。
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引用次数: 0
Advancing the APRN and PA professions through medical staff membership: An organizational case study. 通过医务人员成员资格推进APRN和PA专业:一个组织案例研究。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-06-01 Epub Date: 2025-05-27 DOI: 10.1097/01.JAA.0000000000000098
Paula Brooks, Ebrahim Barkoudah

Abstract: Granting medical staff membership to advanced practice registered nurses (APRNs) and physician associates (PAs) is a national trend endorsed by The Joint Commission in 1983 and by the Centers for Medicare & Medicaid Services in 2012. APRNs and PAs must participate in the system in which medical care policies are made and communicated. Medical staff privileges enable these clinicians to help develop and implement hospital and medical staff policies that improve the quality and appropriateness of patient care. Medical staff membership also encourages a culture that promotes interprofessional and collaborative practice, enhancing and strengthening clinician relationships. Through education and by updating bylaws, rules, and regulations, APRNs and PAs at our facility can now admit patients, and they have a voice and vote in medical staff governance committees that affect their practice.

摘要:向高级执业注册护士(aprn)和医师助理(PAs)授予医务人员会员资格是1983年联合委员会和2012年医疗保险和医疗补助服务中心认可的一种全国性趋势。aprn和pa必须参与医疗保健政策制定和沟通的系统。医务人员特权使这些临床医生能够帮助制定和实施提高患者护理质量和适当性的医院和医务人员政策。医务人员的成员资格也鼓励一种文化,促进跨专业和合作的做法,加强和加强临床医生的关系。通过教育和更新规章制度,我们机构的aprn和pa现在可以接收病人,他们在影响他们实践的医务人员管理委员会中有发言权和投票权。
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引用次数: 0
In the line of duty. 在工作中。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-06-01 Epub Date: 2025-05-27 DOI: 10.1097/01.JAA.0000000000000216
Brian T Maurer
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引用次数: 0
Multisystem immune-related adverse reactions with immune checkpoint inhibitors. 免疫检查点抑制剂的多系统免疫相关不良反应。
IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-06-01 Epub Date: 2025-05-27 DOI: 10.1097/01.JAA.0000000000000211
Amy Jayson, Maria Tsambarlis, Hardik Thakkar, Steven P Ludlow, Misbahuddin Syed

Abstract: Immune checkpoint inhibitors have transformed oncologic practice, producing durable responses in many patients with advanced malignancies. However, these treatments can cause immune-related adverse reactions. This article describes a patient with metastatic non-small cell lung cancer who developed toxicities involving multiple organ systems shortly after receiving combined ipilimumab and nivolumab. Although toxicity is more common in just one organ system, multisystem adverse reactions are possible, and clinicians who recognize and manage these reactions promptly can improve patient outcomes.

免疫检查点抑制剂已经改变了肿瘤学实践,在许多晚期恶性肿瘤患者中产生持久的反应。然而,这些治疗方法可能引起免疫相关的不良反应。这篇文章描述了一位转移性非小细胞肺癌患者,在接受伊匹单抗和纳武单抗联合治疗后不久出现涉及多器官系统的毒性。虽然毒性在一个器官系统中更常见,但多系统不良反应是可能的,及时识别和处理这些反应的临床医生可以改善患者的预后。
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引用次数: 0
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Jaapa-Journal of the American Academy of Physician Assistants
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