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Does Femoral Component Rotation Matter in Functionally Aligned Total Knee Arthroplasty? The Effect of Deviations From the Transepicondylar Axis on Patient-Reported Outcomes at 1 Year. 股骨假体旋转对功能对齐全膝关节置换术有影响吗?经髁轴偏离对患者报告1年预后的影响。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2026-02-01 Epub Date: 2025-09-17 DOI: 10.1055/a-2693-0881
John E Farey, Jordan Chew, Jil A Wood, Darren B Chen, Samuel J Macdessi

Femoral component rotation (FCR) in total knee arthroplasty (TKA) is critical for flexion balance and patellofemoral tracking. Deviations from the transepicondylar axis (TEA) have been linked to poor outcomes. This study aimed to assess the impact of FCR on patient-reported outcomes in functionally aligned (FA) TKAs. A total of 448 robotic-assisted FA TKAs with preresection gap balancing were performed in 393 patients between June 1, 2018, and December 31, 2021. Demographic, radiographic, and patient-reported outcome measures (PROMs) were prospectively collected at baseline and 1 year postoperatively. FCR was set within a range of ± 6 degrees relative to the TEA as part of an FA TKA alignment strategy. The primary outcome was the relationship between final intraoperative FCR and PROMs at 1 year, including the Knee injury and Osteoarthritis Outcome Score-12 (KOOS-12) and the EuroQol 5-Dimension-5-Level (EQ5D-5L) score. Mean FCR was 0.0 degrees (SD ± 2.1 degrees, range: -5.8 to 7.0 degrees). At 1 year, KOOS-12 increased by a mean of 44.1 points (p < 0.01), and EQ5D-5L by 7.6 points (p < 0.01). No significant correlation was found between FCR and KOOS-12 (r = -0.09, p = 0.3). A weak negative correlation existed between increasing external FCR and EQ5D-5L (r = -0.12, p = 0.03). Categorizing FCR into internal (<-2 degrees), neutral (± 2 degrees), and external rotation (≥2 degrees) showed no significant differences in outcomes. FA TKA leads to significant improvements in PROMs, regardless of FCR within a functional range, at 1 year postoperatively. The study is a cross-sectional study providing Level III evidence.

全膝关节置换术(TKA)中股骨假体旋转(FCR)对屈曲平衡和髌股追踪至关重要。经髁轴(TEA)的偏离与预后不良有关。本研究旨在评估FCR对功能对齐(FA) tka患者报告结果的影响。2018年6月1日至2021年12月31日期间,393名患者共进行了448例机器人辅助FA tka,并进行了切除前间隙平衡。在基线和术后1年前瞻性收集人口统计学、放射学和患者报告的结果测量(PROMs)。FCR设置在相对于TEA的±6度范围内,作为FA TKA对准策略的一部分。主要终点是术中最终FCR与1年PROMs的关系,包括膝关节损伤和骨关节炎结局评分-12 (KOOS-12)和EuroQol 5维5水平评分(EQ5D-5L)。平均FCR为0.0度(SD±2.1度,范围:-5.8至7.0度)。1年后,KOOS-12平均增加44.1点(p p r = -0.09, p = 0.3)。体外FCR升高与EQ5D-5L呈弱负相关(r = -0.12, p = 0.03)。将FCR分为内部(
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引用次数: 0
Comparative Efficacy of ChatGPT and Gemini in Addressing Patient Queries on Gonarthrosis and Total Knee Arthroplasty: A Randomized Controlled Trial. ChatGPT和Gemini在解决膝关节病和全膝关节置换术患者询问方面的比较疗效:一项随机对照试验。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2026-02-01 Epub Date: 2025-09-19 DOI: 10.1055/a-2693-0756
Serhat Gurbuz, Bulent Karslioglu, Ahmet Keskin, Niyazi Igde, Mustafa Bugra Ayaz, Yunus Imren

The emergence of artificial intelligence (AI) in health care has created novel opportunities for enhancing patient education and alleviating anxiety. This study seeks to evaluate the effectiveness of two leading AI platforms, ChatGPT and Gemini, in delivering accurate and satisfactory responses to patients with gonarthrosis, considering total knee arthroplasty (TKA). A prospective, randomized controlled trial was conducted involving 100 patients diagnosed with gonarthrosis and indicated for TKA. Each patient posed five questions regarding the surgery and postoperative rehabilitation to both ChatGPT and Gemini. Responses were evaluated by two blinded orthopaedic specialists on a 10-point scale for accuracy and patient satisfaction. Patients additionally evaluated their satisfaction with each response using a 10-point scale. The main outcome measures consisted of the average accuracy scores assessed by specialists and the average satisfaction scores reported by patients. Statistical analysis revealed significant differences between ChatGPT and Gemini in both accuracy and patient satisfaction (p < 0.001). ChatGPT demonstrated better performance with a mean accuracy score of 8.7 ± 0.9 compared with Gemini's 7.2 ± 1.1. Patient satisfaction scores aligned with expert evaluations, with ChatGPT achieving a mean satisfaction score of 8.9 ± 0.8 versus Gemini's 7.5 ± 1.2. Notably, ChatGPT excelled in providing comprehensive explanations of surgical procedures (mean score: 9.2 ± 0.7) and postoperative care (9.1 ± 0.8), whereas Gemini performed better in offering concise summaries of recovery timelines (8.4 ± 0.9). This study demonstrates that ChatGPT offers more accurate and satisfactory responses to patient queries regarding gonarthrosis and TKA compared with Gemini. The findings suggest that AI platforms, particularly ChatGPT, can serve as valuable tools in augmenting patient education and potentially reducing preoperative anxiety. Future studies should investigate the incorporation of AI-assisted information delivery into clinical practice and its long-term effects on patient outcomes.

人工智能(AI)在医疗保健领域的出现为加强患者教育和减轻焦虑创造了新的机会。本研究旨在评估两种领先的人工智能平台ChatGPT和Gemini在为考虑全膝关节置换术(TKA)的关节病患者提供准确和满意的反应方面的有效性。一项前瞻性,随机对照试验进行了100名患者诊断为关节病和TKA适应症。每位患者向ChatGPT和Gemini提出5个关于手术和术后康复的问题。回复由两名盲法骨科专家以10分制的准确性和患者满意度进行评估。此外,患者还使用10分制评估他们对每个反应的满意度。主要结果测量包括专家评估的平均准确性得分和患者报告的平均满意度得分。统计分析显示,ChatGPT和Gemini在准确性和患者满意度方面存在显著差异(p
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引用次数: 0
Tibial Slope Variation Across CPAK Phenotypes: A 3D CT-Based Analysis of Osteoarthritic Knees. CPAK表型的胫骨斜率变化:基于3D ct的骨关节炎膝关节分析。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2026-01-30 DOI: 10.1055/a-2796-8289
Vicente Jesús León-Muñoz, José Hurtado-Avilés, Pablo Sanchez-Urgelles, Francisco Lajara-Marco, Mirian López-López, Fernando Santonja-Medina, Joaquin Moya-Angeler

Introduction: The Coronal Plane Alignment of the Knee (CPAK) classification system categorizes nine phenotypes based on constitutional limb alignment and joint line obliquity. Understanding relationships between CPAK phenotypes and tibial slope could streamline total knee arthroplasty planning. This study investigated the correlations between CPAK classification and medial tibial slope in patients with osteoarthritis.

Materials and methods: A retrospective analysis of 622 cases in 535 patients with osteoarthritis undergoing primary total knee arthroplasty was conducted. Three-dimensional computed tomography imaging with MyPlanner® software determined mechanical lateral distal femoral angle, mechanical medial proximal tibial angle, and medial tibial slope. Statistical analysis included multiple linear regression, Pearson correlation, and one-way ANOVA with Tukey post-hoc testing. Outliers were removed using interquartile range criteria, resulting in 581 knees for final analysis.

Results: Multiple linear regression revealed minimal correlation between coronal alignment and tibial slope (TS = 26.35 - 0.1045 aHKA - 0.1004 JLO; r² = 0.0233). Arithmetic hip-knee-ankle angle and joint line obliquity explained only 2.33% of tibial slope variance. Contour mapping demonstrated no discernible patterns in data distribution. Despite weak correlations, ANOVA identified statistically significant differences between CPAK groups for tibial slope (F = 2.97; P = 0.003). Tukey post-hoc analysis revealed significant differences between CPAK group I and groups V and VII, with mean differences ranging 1.39° to 2.06°.

Conclusions: No clinically meaningful relationship exists between CPAK classification and tibial slope in osteoarthritic knees. While statistical significance differences were observed between certain CPAK groups, the extremely low correlation coefficient and small effect sizes indicate these differences fall within measurement variability and are substantially smaller than tibial slope variations that influence total knee arthroplasty outcomes. CPAK classification cannot reliably predict sagittal plane morphology, necessitating an independent, comprehensive three-dimensional assessment of coronal and sagittal characteristics during surgical planning.

膝关节冠状面对齐(CPAK)分类系统根据体质肢体对齐和关节线倾角对9种表型进行了分类。了解CPAK表型与胫骨坡度的关系可以简化全膝关节置换术计划。本研究探讨骨关节炎患者CPAK分型与胫骨内侧斜度的关系。材料与方法:回顾性分析535例行原发性全膝关节置换术的622例骨关节炎患者的资料。三维计算机断层成像与MyPlanner®软件确定机械外侧股骨远端角度,机械内侧胫骨近端角度和胫骨内侧斜率。统计分析包括多元线性回归、Pearson相关、单因素方差分析和Tukey事后检验。使用四分位数范围标准去除异常值,最终分析581个膝关节。结果:多元线性回归显示冠状位与胫骨斜率相关性最小(TS = 26.35 - 0.1045 aHKA - 0.1004 JLO; r²= 0.0233)。算术髋膝踝角和关节线倾角仅能解释2.33%的胫骨斜率变化。等高线图在数据分布上没有明显的规律。尽管相关性较弱,但方差分析发现CPAK组间胫骨斜率差异有统计学意义(F = 2.97; P = 0.003)。Tukey事后分析显示,CPAK I组与V、VII组之间存在显著差异,平均差异为1.39°至2.06°。结论:膝关节骨性关节炎患者CPAK分型与胫骨斜度无临床意义。虽然在某些CPAK组之间观察到具有统计学意义的差异,但极低的相关系数和较小的效应量表明,这些差异属于测量变异性,并且远远小于影响全膝关节置换术结果的胫骨斜率变化。CPAK分类不能可靠地预测矢状面形态,需要在手术计划时对冠状面和矢状面特征进行独立、全面的三维评估。
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引用次数: 0
Osteophyte Bony Balancing in Robotic Total Knee Arthroplasty: A Surgical Technique and Predictive Algorithm for Soft Tissue Laxity. 机器人全膝关节置换术中的骨赘骨平衡:一种外科技术和软组织松弛的预测算法。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2026-01-29 DOI: 10.1055/a-2796-8119
Olivia Bono, James V Bono

Introduction: The removal of osteophytes during total knee arthroplasty (TKA) results in reduced soft tissue tension, which may result in joint laxity. Thus, for gap balancing, a surgeon may try to predict the effect of osteophyte removal on the resulting flexion and extension gap before any bone cuts are made and before those osteophytes are removed. Posterior osteophytes, however, are relatively inaccessible, since their removal can be done only after posterior bone cuts are made on the femur. Any laxity created by posterior osteophyte removal cannot be corrected by adjusting bone cuts because they have already been made. The authors have developed a predictive algorithm for use in robotic TKA which anticipates the effect of osteophyte removal, allowing adjustment in bony resection before any bone cuts are made.

Materials and methods: The cross-sectional area of the posterior femoral osteophytes is measured on the sagittal plane of the preoperative CAT scan. The authors method of osteophyte correction is to make changes to the tibial cut based on the size and shape of the posterior osteophytes, as they believe the laxity created by osteophyte removal affect both extension and flexion. The amount and specific location of bony resection is then determined based on the size and location (posteromedial vs posterolateral) of the osteophytes.

Results: Through the described technique, the authors have found that the amount of laxity created by osteophyte removal correlates directly to the dimension of the osteophyte over which the soft tissue extends.

Conclusion: The size and shape of initially inaccessible posterior osteophytes, determined using CAT scan-based imaging, was used to create a predictive bony balancing algorithm, designed to be incorporated with the surgeon's preferred bony balancing technique. Our predictive algorithm anticipates the laxity created by osteophyte removal prior to their removal and can be used to alter bone resection parameters and/or implant parameters (e.g., thickness of a tibial liner) to accommodate the increased laxity, allowing for the conservation of bone and correction of deformity.

导读:全膝关节置换术(TKA)中骨赘的去除导致软组织张力降低,这可能导致关节松弛。因此,为了平衡间隙,外科医生可能会在进行任何骨切割和骨赘去除之前,尝试预测骨赘去除对产生的屈伸间隙的影响。然而,后路骨赘相对难以切除,因为它们只能在股骨后路骨切割后切除。由于后路骨赘清除造成的任何松弛都不能通过调整骨切口来纠正,因为它们已经发生了。作者已经开发了一种用于机器人TKA的预测算法,该算法可以预测骨赘去除的效果,允许在任何骨切割之前调整骨切除。材料和方法:在术前CAT扫描矢状面测量股骨后骨赘的横截面积。作者矫正骨赘的方法是根据后路骨赘的大小和形状对胫骨切口进行改变,因为他们认为骨赘去除造成的松弛会影响伸展和屈曲。然后根据骨赘的大小和位置(后内侧vs后外侧)确定骨切除的数量和具体位置。结果:通过所描述的技术,作者发现骨赘去除产生的松弛量与软组织延伸的骨赘的尺寸直接相关。结论:使用基于CAT扫描的成像确定最初无法进入的后路骨赘的大小和形状,用于创建预测性骨平衡算法,该算法旨在与外科医生首选的骨平衡技术相结合。我们的预测算法在骨赘去除之前预测骨赘去除所产生的松弛,并可用于改变骨切除参数和/或植入物参数(例如胫骨衬里的厚度)以适应增加的松弛,从而保护骨骼和矫正畸形。
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引用次数: 0
Revision Total Knee Arthroplasty for Arthrofibrosis. 全膝关节置换术治疗关节纤维化。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2026-01-29 DOI: 10.1055/a-2778-9096
Rolanda Willacy, Giles R Scuderi

Arthrofibrosis is a common issue that can occur after a primary total knee arthroplasty (TKA) and is a significant cause of patient dissatisfaction. As the annual incidence of TKA in the United States rises, the prevalence of arthrofibrosis will rise. The prevalence of this outcome has been reported between 1.3 and 5.3%. The range of values is attributed to the varying quantitative thresholds of flexion and/or extension loss used to define arthrofibrosis. This causes a significant burden on the healthcare system, with a reported 27.5% of the 90-day readmissions after TKA due to arthrofibrosis. This can lead to debilitating results for the affected patients with pain, abnormal gait, fatigue, and difficulty rising from the seated position. The definition of stiffness has changed over the years. This underscores the increasing expectations that both surgeons and patients have for total knee replacements. Management of arthrofibrosis includes both nonoperative and operative modalities. The treatment algorithm includes physical therapy and manipulation under anesthesia (MUA). Physical therapy is most used, while revision arthroplasty is typically reserved as a last resort.

关节纤维化是原发性全膝关节置换术(TKA)后常见的问题,也是患者不满意的重要原因。随着TKA在美国年发病率的上升,关节纤维化的患病率也将上升。据报道,这一结果的发生率在1.3%至5.3%之间。该数值的范围归因于用于定义关节纤维化的屈曲和/或伸展损失的不同定量阈值。这给医疗保健系统带来了沉重的负担,据报道,TKA后90天内再入院的患者中有27.5%是由于关节纤维化。这会导致患者身体虚弱,出现疼痛、步态异常、疲劳和难以从坐姿起身。多年来,刚度的定义发生了变化。这强调了外科医生和患者对全膝关节置换术的期望越来越高。关节纤维化的治疗包括非手术和手术两种方式。治疗算法包括物理治疗和麻醉下操作(MUA)。物理治疗是最常用的,而翻修关节置换术通常作为最后的手段。
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引用次数: 0
Diagnosis and Clinical Assessment of Arthrofibrosis after Total Knee Arthroplasty: Challenges and Evolving Standards. 全膝关节置换术后关节纤维化的诊断和临床评估:挑战和不断发展的标准。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2026-01-27 DOI: 10.1055/a-2780-8167
Amir Human Hoveidaei, Chase W Smitterberg, Reza M Katanbaf, Monica Misch, Ysa Le, James Nace, Ronald E Delanois, Michael A Mont

Arthrofibrosis is a common complication following total knee arthroplasty (TKA), characterized by excessive fibrous tissue formation within the joint, leading to restricted range of motion (ROM), pain, and functional impairment. Accurate diagnosis is essential for distinguishing arthrofibrosis from other causes of postoperative knee stiffness, such as infection, mechanical block, or malalignment. This review aims to explore current diagnostic methods and evolving standards for arthrofibrosis after TKA, focusing on (1) clinical differentiation from other causes of knee stiffness; (2) assessment and diagnostic criteria; (3) imaging, laboratory, and histopathological techniques; and (4) an integrated diagnostic algorithm and future directions. Diagnosis is primarily based on persistent ROM limitation (flexion <90 degrees or extension >5 degrees) for more than 12 weeks, after excluding infection and mechanical causes. Advanced magnetic resonance imaging (MRI) with metal artifact reduction techniques can be used to visualize intra-articular fibrosis, with an MRI-based synovial classification correlating with ROM deficits and severity. Synovial fluid analysis helps rule out infection, and histopathology is employed when the diagnosis remains unclear. The study proposes a stepwise diagnostic algorithm that integrates clinical, imaging, and laboratory findings and discusses future directions for optimizing diagnosis and treatment pathways to improve patient outcomes.

关节纤维化是全膝关节置换术(TKA)后常见的并发症,其特征是关节内纤维组织形成过多,导致活动范围受限(ROM)、疼痛和功能损害。准确的诊断对于区分关节纤维化与术后膝关节僵硬的其他原因(如感染、机械阻滞或对齐不良)至关重要。本综述旨在探讨TKA后关节纤维化的现有诊断方法和不断发展的标准,重点关注1)膝关节僵硬与其他原因的临床区分;2)评估诊断标准;3)影像学、实验室和组织病理学技术;4)综合诊断算法及未来发展方向。在排除感染和机械原因后,诊断主要基于持续ROM限制(屈曲< 90°或伸直≤5°)超过12周。先进的磁共振成像(MRI)与金属伪影还原技术可用于观察关节内纤维化,基于MRI的滑膜分类与ROM缺陷和严重程度相关。滑液分析有助于排除感染,当诊断不明确时采用组织病理学。该研究提出了一种整合临床、影像学和实验室结果的逐步诊断算法,并讨论了优化诊断和治疗途径以改善患者预后的未来方向。
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引用次数: 0
Comparable Outcome Scores for Medial Collateral Ligament Reconstruction and Repair in Isolated and Combined Grade III Injuries, with Lower Rates of Complication Following Repair at Two-Year Follow-Up. 独立和联合III级损伤的内侧副韧带重建和修复的可比结果评分,在两年随访中修复后并发症发生率较低。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2026-01-27 DOI: 10.1055/a-2778-8771
Benjamin Tyler Lack, Justin T Childers, Colton C Mowers, Andrea M Javier, Garrett R Jackson, Derrick M Knapik, Steven F DeFroda, Clayton W Nuelle, Jorge Chahla

Title: Comparable Outcome Scores for Medial Collateral Ligament Reconstruction and Repair in Grade III Injuries, with Lower Rates of Complication Following Repair at Two-Year Follow-Up: A Systematic Review Purpose: To compare patient-reported outcomes and complications of MCL repair versus reconstruction in patients with grade III medial collateral ligament (MCL) injuries, and to report whether these were isolated or associated lesions, with minimum 2-year follow-up.

Methods: A comprehensive search of PubMed, Scopus, and Embase was conducted from database inception to August 2024 according to PRISMA 2020 guidelines. Studies reporting outcomes and complications following repair or reconstruction of grade III MCL injuries with ≥2-year follow-up were included. Data on concomitant procedures were extracted to determine the frequency of isolated versus combined lesions.

Results: Twelve studies met criteria, comprising 388 patients: 277 underwent MCL reconstruction and 111 underwent MCL repair. Mean follow-up was 37.6 months for reconstruction and 56.2 months for repair. The majority of injuries were combined lesions, with concomitant ACL reconstruction performed in 70.8% of reconstruction and 58.6% of repair cohorts. Postoperative IKDC scores ranged 54.3-89 for reconstruction and 79.1-88.8 for repair; Lysholm scores ranged 59.4-94.8 and 83.8-98.5, respectively. Complications occurred in 14.4% of reconstruction and 4.5% of repair patients, most commonly range of motion deficits. Reoperation rates were comparable (6.1% vs 7.2%).

Conclusion: Both reconstruction and repair for grade III MCL injuries yielded favorable outcomes at ≥2-year follow-up. MCL repair demonstrated slightly higher IKDC and Lysholm scores with fewer complications overall. Most cases involved combined MCL and ACL injuries, highlighting the rarity of isolated grade III MCL lesions.

目的:比较III级内侧副韧带(MCL)损伤患者报告的MCL修复与重建的结果和并发症,并报告这些是孤立的还是相关的病变,至少随访2年。方法:根据PRISMA 2020指南,从数据库建立到2024年8月,对PubMed、Scopus和Embase进行综合检索。研究报告III级MCL损伤修复或重建后的结果和并发症,随访≥2年。提取伴随手术的数据以确定单独病变与合并病变的频率。结果:12项研究符合标准,包括388例患者:277例进行了MCL重建,111例进行了MCL修复。重建组平均随访37.6个月,修复组平均随访56.2个月。大多数损伤是合并病变,在70.8%的重建和58.6%的修复队列中,同时进行了ACL重建。术后重建IKDC评分54.3-89分,修复IKDC评分79.1-88.8分;Lysholm得分分别为59.4-94.8分和83.8-98.5分。14.4%的重建患者和4.5%的修复患者出现并发症,最常见的是运动范围缺损。再手术率比较(6.1% vs 7.2%)。结论:III级MCL损伤的重建和修复在≥2年的随访中均获得了良好的结果。MCL修复显示IKDC和Lysholm评分略高,并发症总体较少。大多数病例涉及MCL和ACL合并损伤,突出了孤立的III级MCL病变的罕见性。
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引用次数: 0
Arthrofibrosis After Total Knee Arthroplasty Managed with Manipulation Under Anesthesia. 全膝关节置换术后的关节纤维化。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2026-01-22 DOI: 10.1055/a-2779-0459
Lawrence Jajou, Giles R Scuderi

Arthrofibrosis after total knee arthroplasty (TKA) is the result of excessive scar formation because of the inflammatory insult of surgery. This formation can lead to significant loss of range of motion, pain, and functional deficits requiring further treatment. Although much has been researched on arthrofibrosis, it continues to lack definitive diagnostic testing. This has led to an array of approaches and treatments to relieve patients of this complication. In response to the inflammatory insult caused by TKA, arthrofibrosis occurs because of an overactivation and proliferation of myofibroblasts. This leads to an abundant deposition of type I collagen and scar tissue formation. This general cascade has been found to be associated with multiple signaling pathways involving primarily transforming growth factor-beta. Additionally, there is a multifactorial component of risk factors and comorbidities, which contribute to the formation of arthrofibrosis. Arthrofibrosis is diagnosed as both a clinical diagnosis and a diagnosis of exclusion. Using the patient's history, clinical examination, and diagnostic testing to rule out other etiologies, one can obtain the diagnosis of arthrofibrosis. While stiffness is an umbrella term that is commonly used interchangeably with arthrofibrosis, it is imperative to use the diagnostic testing to systematically rule out other causes of stiffness. There is no definitive imaging, biopsy, or biomarker test specific for arthrofibrosis currently, which makes obtaining a definitive diagnosis difficult. Nonoperative and operative treatment options are available for the treatment of arthrofibrosis. Most conservative approaches begin with physical therapy, appropriate pain management, and oral anti-inflammatory medication. Treatment options rise in invasiveness with manipulation under anesthesia, arthroscopic lysis of adhesions, open lysis of adhesions, and ultimately revision TKA. This review will focus on the role of manipulation under anesthesia in the setting of arthrofibrosis.

全膝关节置换术(TKA)后的关节纤维化是由于手术的炎症性损伤导致过度瘢痕形成的结果。这种形成可导致明显的活动范围丧失、疼痛和功能缺陷,需要进一步治疗。尽管已经对关节纤维化进行了大量研究,但仍然缺乏明确的诊断测试。这导致了一系列的方法和治疗来减轻这种并发症的患者。病理生理学:在TKA引起的炎症性损伤的反应中,由于肌成纤维细胞的过度激活和增殖而发生关节纤维化。这导致I型胶原蛋白的大量沉积和疤痕组织的形成。这种普遍的级联已被发现与多种主要涉及转化生长因子- β (tgf - β)的信号通路有关。此外,有一个多因素的危险因素和合并症,有助于形成关节纤维化。诊断:关节纤维化诊断为临床诊断和排除诊断。通过患者的病史、临床检查和诊断测试来排除其他病因,可以得到关节纤维化的诊断。虽然僵硬是一个总括性术语,通常与关节纤维化互换使用,但必须使用诊断测试系统地排除僵硬的其他原因。目前尚无针对关节纤维化的明确的影像学、活检或生物标志物检测,这使得获得明确的诊断变得困难。治疗:关节纤维化有非手术和手术两种治疗方法。大多数保守的治疗方法以物理治疗、适当的疼痛管理和口服消炎药开始。治疗选择增加了麻醉下操作的侵入性,关节镜下粘连松解,开放粘连松解,最终翻修全膝关节置换术。本文将重点讨论麻醉下操作在关节纤维化中的作用。
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引用次数: 0
Return to Sport Following ACL Repair: A Systematic Review. ACL修复后恢复运动:系统回顾。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2026-01-21 DOI: 10.1055/a-2779-0367
Cooper Williams, Antonio Da Costa, Aghdas Movassaghi, Het Chavda, Vani Sabesan

Anterior cruciate ligament (ACL) injuries are among the most common sports-related knee injuries, affecting athletes across varying levels of competition. ACL repair procedures have become a popular treatment option to repair these lesions. There is a need for a comprehensive analysis of recent studies among a growing body of literature to better understand return to sport (RTS), return to previous level (RPL), and timing of RTS following these procedures. A systematic review was performed using the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. A literature search of PubMed, Embase, Scopus, and SPORTDiscus databases was performed on October 11, 2024. Two independent reviewers screened 2,098 articles. The inclusion criteria included studies from 2000 to the present, a minimum of 12-month follow-up, level of evidence (LOE) I to IV, English language, and reported outcomes after ACL repair procedures with RTS data. Data were stratified by ACL repair technique for subgroup analysis. RTS, RPL, and RTS timing were reported as ranges to reflect study variability. The 16 studies included 614 athletes with RTS rates ranging from 36% to 100%. Seven studies report RPL encompassing 342 athletes with RPL rates ranging from 60% to 81%. The average time for athletes to RTS ranged from 5.9 to 11.9 months. ACL repair with bone marrow stimulation achieved RTS rates ranging from 78% to 92%. Primary repair techniques demonstrated RTS rates from 67% to 100%, while primary repair with internal brace techniques demonstrated RTS rates ranging from 36% to 100%. RTS rates following the Bridge-Enhanced ACL Repair (BEAR) technique were only reported in one study, and reported an RTS rate at 88%. The majority of patients undergoing ACL repair RTS, with a majority also returning to preinjury levels between 4 and 11.9 months postsurgery. ACL repair techniques are a viable treatment option in the correct patient population.LOE is IV; systematic review of level IV studies.

前言:前交叉韧带(ACL)损伤是最常见的与运动相关的膝关节损伤之一,影响着不同水平的运动员。前交叉韧带修复手术已成为修复这些病变的流行治疗选择。有必要对越来越多的文献中最近的研究进行综合分析,以便更好地理解重返运动(RTS)、重返先前水平(RPL)以及遵循这些程序重返运动的时间。方法:采用2020年系统评价和荟萃分析首选报告项目(PRISMA)指南进行系统评价。检索PubMed、Embase、Scopus、SportsDISCUS数据库,检索时间为2024年10月11日。两名独立审稿人筛选了2098篇文章。纳入标准为:2000年至今的研究,至少随访12个月,证据水平1-4,英语语言,ACL修复手术后报告的RTS数据结果。采用ACL修复技术对数据进行分层亚组分析。RTS、RPL和RTS时间被报告为反映研究可变性的范围。结果:16项研究包括614名运动员,RTS率从36%到100%不等。七项研究报告了342名运动员的RPL, RPL率从60%到81%不等。运动员恢复运动的平均时间从5.9个月到11.9个月不等。骨髓刺激修复ACL的RTS率为78-92%。初级修复技术显示RTS率为67-100%,而内部支架技术的初级修复显示RTS率为36-100%。BEAR技术后的RTS率仅在一项研究中报道,报告的运动恢复率为88%。结论:大多数接受前交叉韧带修复的患者恢复运动,大多数患者在术后4-11.9个月恢复到损伤前水平。ACL修复技术在正确的患者群体中是一种可行的治疗选择。
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引用次数: 0
Increased Time from Onset of Symptoms to Revision Anterior Cruciate Ligament Reconstruction is Associated with More Intra-Articular Pathology. 从症状出现到前交叉韧带重建翻修的时间增加与更多的关节内病理相关。
IF 1.6 4区 医学 Q3 ORTHOPEDICS Pub Date : 2026-01-20 DOI: 10.1055/a-2778-8916
George Durisek, Bryce Dzubara, Zachary Burnett, Ryan H Barnes, David C Flanigan, Parker Cavendish, Eric Milliron, Robert A Duerr, Christopher C Kaeding, Robert A Magnussen

This cohort study aimed to identify whether time greater than 3 months between the onset of new symptoms of instability after primary anterior cruciate ligament (ACL) reconstruction (ACLR) and subsequent revision ACLR influences outcomes of revision surgery. We hypothesized greater than 3 months from onset of symptoms to revision ACLR is associated with increased intra-articular damage and poorer outcomes following revision ACLR. A retrospective chart review was conducted to identify patients who underwent revision ACLR at a large tertiary referral institution between 2008 and 2019. Demographic, surgical, and postsurgical data were collected. Patients who underwent revision ACLR within 3 months of documented graft symptomology were defined as the Early Revision group, and patients who underwent revision ACLR at or greater than 3 months after onset of graft symptomology were defined as the Late Revision group. Demographic data, intraoperative findings, subsequent graft failure, and patient-reported outcomes were compared between the groups. A total of 74 patients met inclusion criteria. Patients in the Late Revision group were more likely to have cartilage damage in the patella, trochlea, medial tibial plateau, lateral femoral condyle, and lateral tibial plateau. Patients in the Late Revision group were also more likely to have concomitant lateral meniscus tears. Medial meniscus tears identified at time of surgery in this group were also less likely to be deemed repairable. No significant differences were noted in postoperative Knee Injury and Osteoarthritis Outcome Scores, Marx Activity scores, or ACL graft retear risk based on the time from injury to surgery. Undergoing revision ACLR more than 3 months after graft tear is associated with more severe articular cartilage damage, more frequent lateral meniscus pathology, and a greater incidence of irreparable medial meniscus tears. No significant differences in patient-reported outcomes or revision graft failure risk were observed. LEVEL OF EVIDENCE:  III.

本队列研究旨在确定原发性前交叉韧带(ACLR)重建(ACLR)后出现新的不稳定症状与随后的ACLR翻修之间的时间间隔是否大于3个月影响翻修手术的结果。我们假设从症状出现到改良ACLR超过3个月与改良ACLR后关节内损伤增加和预后较差相关。材料和方法:对2008年至2019年在一家大型三级转诊机构接受改良ACLR的患者进行回顾性图表回顾。收集人口统计、手术和术后数据。在移植物症状出现后3个月内接受ACLR翻修的患者被定义为早期翻修组,在移植物症状出现后3个月或以上接受ACLR翻修的患者被定义为晚期翻修组。比较两组之间的人口统计数据、术中发现、随后的移植物失败和患者报告的结果。结果:74例患者符合纳入标准。晚期翻修组患者髌骨、滑车、胫骨内侧平台、股骨外侧髁和胫骨外侧平台软骨损伤的可能性更大。晚期翻修组的患者也更有可能同时出现外侧半月板撕裂。手术时发现的内侧半月板撕裂在这组中也不太可能被认为是可修复的。术后kos评分、Marx活动评分或ACL移植物再撕裂风险在损伤至手术时间上无显著差异。结论:移植骨撕裂后3个月以上行ACLR翻修与更严重的关节软骨损伤、更频繁的外侧半月板病理以及更大的不可修复的内侧半月板撕裂相关。在患者报告的结果或移植失败风险方面没有观察到显著差异。
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引用次数: 0
期刊
Journal of Knee Surgery
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