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Efficacy of partial tonsillectomy in periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome: a STROBE retrospective observational study. 扁桃体部分切除术对周期性发热、口腔炎、咽炎和腺炎综合征的疗效:STROBE 回顾性观察研究。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-09-24 DOI: 10.1016/j.anorl.2024.07.010
T Banh Chong, O Sagot, M Alexis, C Brehin, K Brochard, Y Gallois

Introduction: PFAPA (Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis) or Marshall syndrome is the most frequent cause of recurrent auto-inflammatory fever in children. Frequent episodes impair the child's quality of life and family life. Total tonsillectomy demonstrated efficacy in improving symptoms, but few studies assessed partial tonsillectomy in this indication. The aim of the present study was to assess postoperative course after partial tonsillectomy for PFAPA syndrome, with comparison to total tonsillectomy.

Materials and methods: This retrospective cohort study adhered to STROBE guidelines. It included children with PFAPA syndrome on EUROFEVER criteria, treated by partial or total tonsillectomy between January 1, 2011 and December 31, 2022 in our university hospital center. For comparisons, the significance threshold was set at P<0.005.

Results: Thirty-six children were included: 16 with partial and 20 with total tonsillectomy. With partial tonsillectomy, the number of episodes decreased by 10 per year (range, 5-21) (P<0.005) over 6 years' follow-up. The decrease was 50% with partial tonsillectomy and 93% with total tonsillectomy (P=0.056). The decrease in number was statistically suggestive (P=0.028). There were no complications with partial tonsillectomy and 2 patients with complications (10%) with total tonsillectomy. Two of the 16 patients with partial tonsillectomy (12.5%) required totalization, achieving remission in both cases.

Conclusion: Partial tonsillectomy significantly reduced the frequency, duration and intensity of postoperative episodes in PFAPA syndrome. It may be less effective than total tonsillectomy, but has a lower risk of complications awaiting remission in adolescence.

简介PFAPA(周期性发热、阿弗他口腔炎、咽炎、腺炎)或马歇尔综合征是儿童反复自身炎症性发热的最常见原因。频繁发作会影响儿童的生活质量和家庭生活。扁桃体全切除术在改善症状方面具有显著疗效,但很少有研究对扁桃体部分切除术在这一适应症中的应用进行评估。本研究旨在评估 PFAPA 综合征扁桃体部分切除术后的疗程,并与全扁桃体切除术进行比较:这项回顾性队列研究遵循了 STROBE 指南。研究对象包括2011年1月1日至2022年12月31日期间在本大学医院中心接受扁桃体部分或全部切除术治疗的符合EUROFEVER标准的PFAPA综合征患儿。比较的显著性阈值设定为PResults:共纳入 36 名儿童:16名儿童接受了扁桃体部分切除术,20名儿童接受了扁桃体全部切除术。扁桃体部分切除术后,每年发病次数减少了 10 次(5-21 次不等)(PC 结论:扁桃体部分切除术显著减少了扁桃体炎的发病率:扁桃体部分切除术明显减少了 PFAPA 综合征术后发作的频率、持续时间和强度。与全扁桃体切除术相比,部分扁桃体切除术的效果可能较差,但并发症风险较低,可在青春期等待缓解。
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引用次数: 0
Infraorbital hypoesthesia after diving. 潜水后眶下感觉减退。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-09-20 DOI: 10.1016/j.anorl.2024.09.005
J-B Morvan, J-B Caruhel, M Chery, V Maso, A Crambert
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引用次数: 0
Middle-ear osteolytic transthyretin amyloidosis: A CARE case report. 中耳溶骨性转甲状腺素淀粉样变性病:CARE病例报告。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-09-17 DOI: 10.1016/j.anorl.2024.09.002
C Maquet, A Willemet, A Francois, F Crampon, S Deneuve

Introduction: Wild-type transthyretin amyloidosis (ATTRwt) is a rare but serious disease that is underestimated due to asymptomatic progression. Cardiac deposits worsen prognosis, highlighting the importance of early detection for preventive treatment.

Case report: An elderly patient presented with an osteolytic lesion of the middle ear. Pathology diagnosed amyloid transthyretin deposits associated with cholesteatoma.

Discussion: Identifying reliable markers to screen for risk of cardiac amyloidosis is important, due to poor prognosis. Recent studies found higher prevalence of hearing loss in ATTRwt than in the general population. The present case identified the middle ear as a target of ATTR, which could improve our understanding of the pathophysiology.

简介野生型转甲状腺素淀粉样变性(ATTRwt)是一种罕见但严重的疾病,由于无症状进展而被低估。心脏沉积物会使预后恶化,这突出了早期检测对预防性治疗的重要性:病例报告:一名老年患者出现中耳溶骨性病变。病理诊断为胆脂瘤相关的淀粉样转甲状腺素沉积:讨论:由于心脏淀粉样变性的预后较差,因此确定可靠的标志物来筛查心脏淀粉样变性的风险非常重要。最近的研究发现,ATTRwt 患者听力损失的发生率高于普通人群。本病例确定了中耳是 ATTR 的靶点,这有助于加深我们对病理生理学的理解。
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引用次数: 0
IgG4-related disease with primary otologic manifestations. 具有原发性耳科表现的 IgG4 相关疾病。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-09-04 DOI: 10.1016/j.anorl.2024.07.004
S Lu, J Peng, L Cui, Y Li
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引用次数: 0
Systematic MRI in post-COVID-19 anosmia might not be necessary 可能没有必要对 COVID-19 后的无嗅症进行系统的 MRI 检查。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.anorl.2024.02.005
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引用次数: 0
Cervical approach for prestyloid parapharyngeal pleomorphic adenoma resection 咽旁多形性腺瘤前淀粉样变性切除术的颈部入路。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.anorl.2024.03.005

Objective

To describe the key points of cervical resection for prestyloid parapharyngeal pleomorphic adenoma and to discuss the role of modern imaging.

Observation

Retrospective case series of 10 patients (4 women and 6 men, age 29–63 years) with prestyloid parapharyngeal pleomorphic adenoma with 2 to 8 cm largest diameter on MRI, consecutively resected via a cervical approach between 2000 and 2020 in a French tertiary university referral care center. Seven patients had a minimum 10 years’ follow-up, and one was lost to follow-up before the fifth postoperative year. Peri- and postoperative complications comprised great auricular nerve transection without subsequent symptomatic neuroma (2 patients), associated transoral approach to free the upper pole of the adenoma (2 patients), capsule effraction (3 patients), and hematoma (1 patient). There were no cases of facial paresis or palsy, other cranial nerve impairment, trismus, auriculotemporal or first-bite syndrome. One of the three patients with capsule effraction showed local recurrence at month 17.

Conclusion

In agreement with previous reports, the present case series confirmed the role of the cervical approach to resect prestyloid parapharyngeal pleomorphic adenoma, and hence the need to continue teaching it.
目的:描述咽旁多形性腺瘤颈部切除术的要点,并讨论现代影像学的作用:描述咽旁前叶多形性腺瘤颈部切除术的要点,并讨论现代影像学的作用:回顾性病例系列:10 例患者(4 名女性和 6 名男性,年龄 29-63 岁)均患有前淀粉样咽旁多形性腺瘤,磁共振成像显示其最大直径为 2-8 厘米,2000 年至 2020 年期间在一家法国三级大学转诊护理中心连续通过颈部入路进行了切除。七名患者接受了至少十年的随访,一名患者在术后第五年前失去了随访机会。围手术期和术后并发症包括大耳廓神经横断但随后没有症状的神经瘤(2 名患者)、相关经口方法游离腺瘤上极(2 名患者)、囊肿脱出(3 名患者)和血肿(1 名患者)。没有出现面瘫或麻痹、其他颅神经损伤、三叉神经痛、耳颞综合征或第一咬合综合征的病例。三名囊肿脱出患者中有一人在第 17 个月时出现局部复发:与之前的报道一致,本病例系列证实了颈部入路切除咽旁多形性腺瘤的作用,因此有必要继续开展相关教学。
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引用次数: 0
Systemic therapies for salivary gland cancer: Adenoid cystic carcinoma. REFCOR recommendations by the formal consensus method 唾液腺癌的系统疗法:腺样囊性癌。REFCOR通过正式共识法提出的建议
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.anorl.2023.11.009

Objective

To determine the therapeutic indications for systemic medical treatment in the management of adenoid cystic carcinoma (ACC) according to the clinical situation.

Materials and methods

The French Network of Rare Head and Neck Tumors (REFCOR) formed a steering group, which drafted a narrative review of the literature published on Medline and proposed recommendations. The level of adherence to the recommendations was then assessed by a rating group, according to the formal consensus method.

Results

ACCs are rare tumors and there is currently insufficient evidence to indicate chemotherapy at the localized stage. At the metastatic stage, progression is often slow. In case of oligometastatic ACC, local treatment should be discussed. The most often indolent nature of polymetastatic ACC can allow management by active surveillance. Molecular screening is recommended, for abnormalities potentially accessible to targeted therapy.

Conclusion

ACCs are rare tumors for which there are currently few effective medical treatments. It is therefore recommended to include patients in clinical trials.
材料与方法法国罕见头颈部肿瘤网络(REFCOR)成立了一个指导小组,该小组对 Medline 上发表的文献进行了叙述性综述,并提出了建议。结果ACCs是一种罕见肿瘤,目前还没有足够的证据表明可以在局部阶段进行化疗。在转移阶段,病情发展通常比较缓慢。对于少转移性 ACC,应讨论局部治疗。多发转移性 ACC 通常病情较轻,可以通过积极的监测进行治疗。建议进行分子筛查,以确定是否存在可用于靶向治疗的异常。因此,建议将患者纳入临床试验。
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引用次数: 0
Sustainable ENT: international collaboration is key 可持续的环境技术:国际合作是关键
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.anorl.2024.02.013
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引用次数: 0
An unusual case of cervical cellulitis 一个不寻常的宫颈蜂窝组织炎病例。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.anorl.2024.05.001
{"title":"An unusual case of cervical cellulitis","authors":"","doi":"10.1016/j.anorl.2024.05.001","DOIUrl":"10.1016/j.anorl.2024.05.001","url":null,"abstract":"","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"141 5","pages":"Pages 308-309"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140903584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A century ago, the birth of the decibel 一个世纪前,分贝诞生。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2024-09-01 DOI: 10.1016/j.anorl.2024.06.002
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引用次数: 0
期刊
European Annals of Otorhinolaryngology-Head and Neck Diseases
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