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Mental Illnesses and Stigma among Medical Undergraduates in India. 印度医学本科生的精神疾病和耻辱感。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-29 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4523
Semanti Das, Sunom Merab Lepcha, Ashish Pundhir, Senthil Amudhan

The current Medical Education system of India, with its enormous workload and academic demands tend to cause the medical students stress. There is evidence showing medical students at a higher risk of depression, anxiety and burnout compared to other Indian students. Despite, the huge reported numbers, the proportion of students and doctors who seek help for their problems is alarmingly low. One of the reasons provided for the same is stigma towards mental health and an apprehension regarding labels and treatment history on the careers of the students. Increased awareness and with a National Health Programme catered towards mental health, there has been a boost in the utilization and provision of mental health services but it rarely translates into better mental health facilities for the healthcare providers. The special set of challenges faced by a medical students are gradually being recognized and efforts are being made to address them. Curriculum guidelines, teaching methods, student welfare centres and helplines have been the areas of intervention. There should also be changes in approaches towards the students who face problems and providing a safe environment for them to discuss their problems, including encouraging peer support. Thus, a fine balance needs to be present between ensuring the protection of the mental health of a medical student and ensuring a quality medical education for them. Further exploration to address stigma and building empathy among the students and evaluation of the intervention methods devised to address the same becomes very necessary to ensure fruitful interventions. It is the need of the hour to help Indian Medical students overcome their struggles with mental health.

印度目前的医学教育体系,其巨大的工作量和学术要求往往会给医学生带来压力。有证据表明,与其他印度学生相比,医学生患抑郁症、焦虑症和职业倦怠的风险更高。尽管报告的人数众多,但寻求帮助的学生和医生比例却低得惊人。其中一个原因是对心理健康的轻蔑,以及对学生职业生涯中的标签和治疗史的担忧。随着人们对精神健康认识的提高和国家健康计划的实施,精神健康服务的利用率和提供量都有所提高,但这很少能转化为医疗服务提供者更好的精神健康设施。医学生所面临的一系列特殊挑战正逐渐被人们所认识,并正在努力加以解决。课程指南、教学方法、学生福利中心和求助热线都是需要干预的领域。此外,还应改变对待面临问题的学生的方法,为他们提供一个安全的环境来讨论他们的问题,包括鼓励同伴互助。因此,需要在确保保护医学生的心理健康和确保为他们提供高质量的医学教育之间取得微妙的平衡。为确保干预措施取得成效,有必要进一步探索如何解决耻辱化问题,在学生中建立共鸣,并对为解决这些问题而设计的干预方法进行评估。帮助印度医科学生克服心理健康方面的困难是当务之急。
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引用次数: 0
Social and Behavioural Change Communication Challenges, Opportunities and Lessons from Past Public Health Emergencies and Disease Outbreaks: A Scoping Review. 社会和行为改变沟通的挑战、机遇以及从以往公共卫生突发事件和疾病爆发中吸取的经验教训:范围审查》。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-23 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4418
Laston Gonah, Sibusiso Cyprian Nomatshila

Background: Documentation of social behavioural change communication (SBCC) regarding challenges, opportunities and lessons drawn from past public health emergencies is worthwhile to inform priorities for future response efforts. Aim: The aim of this review is to scope the evidence on social behavioural change communication regarding challenges, opportunities and lessons drawn from Ebola, coronavirus disease 2019 (COVID-19), monkeypox and cholera outbreaks from studies published before March 2024, and suggest priorities for future response efforts. Methods: A Boolean strategy was used to search electronic databases for relevant published articles, complemented by relevant studies identified from reference lists. Results: The challenges, opportunities, lessons learnt and priorities for SBCC were consistent across study contexts, showing marked variations over time. The significance of technology, infodemic management, and behavioural data generation emerged more frequently and became increasingly important over time. Identified challenges were uptake hesitancy, limited capacity to undertake infodemic management, inadequate funding and human resources for SBCC, competing priorities, parallel or conflicting interventions due to inadequate coordination, difficulties evaluating SBCC programmes and missed opportunities for integration into routine programmes. Existing supportive structures for SBCC, strong political will and participation, as well as rapid information exchange enabled by technological advancement, represented opportunities for enhancing the effectiveness of SBCC programmes. Key lessons were that a multisectoral approach and coordination, partnership and active collaboration amongst stakeholders; building/strengthening trust, target population segmentation and localization of interventions, are important for enhancing the effectiveness of SBCC programmes. Political will, involvement and participation represent the core of social behavioural change (communication) interventions during a public health emergency. Conclusion: SBCC programming for future response to public health emergencies and disease outbreaks should consider the diverse assortment of benefits, threats/challenges and opportunities brought about by technology, infodemics and behavioural data generation to be more effective.

背景:社会行为改变沟通(SBCC)在过去的公共卫生突发事件中面临的挑战、机遇和吸取的教训的文献值得为未来应对工作的优先事项提供参考。目的:本综述旨在从 2024 年 3 月之前发表的研究中,对有关埃博拉、冠状病毒病 2019 (COVID-19)、猴痘和霍乱疫情所带来的挑战、机遇和教训的社会行为改变沟通证据进行梳理,并就未来应对工作的优先事项提出建议。方法:采用布尔策略在电子数据库中搜索已发表的相关文章,并辅以从参考文献列表中确定的相关研究。结果:在不同的研究背景下,SBCC 所面临的挑战、机遇、经验教训和优先事项是一致的,但随着时间的推移出现了明显的变化。随着时间的推移,技术、信息管理和行为数据生成的重要性出现得更频繁,也变得越来越重要。已确定的挑战包括:在采用方面犹豫不决、进行信息管理的能力有限、用于 SBCC 的资金和人力资源不足、相互竞争的优先事项、因协调不足而平行或相互冲突的干预措施、难以评估 SBCC 计划以及错失将其纳入常规计划的机会。SBCC 的现有支持结构、强烈的政治意愿和参与,以及技术进步带来的快速信息交流,都是提高 SBCC 计划有效性的机会。主要的经验教训是,多部门方法和利益相关者之间的协调、伙伴关系和积极合作;建立/加强信任、目标人群的细分和干预措施的本地化,对于提高 SBCC 计划的有效性非常重要。在突发公共卫生事件中,政治意愿、介入和参与是改变社会行为(传播)干预措施的核心。结论未来应对公共卫生突发事件和疾病暴发的社会行为变化(SBCC)计划应考虑到技术、信息和行为数据生成所带来的各种好处、威胁/挑战和机遇,以便更加有效。
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引用次数: 0
Fostering Professional Identity Formation and Motivation for Joining Nursing and Midwifery Programmes among Undergraduate Nursing/Midwifery Students and Recent Graduates in Uganda. 促进乌干达护理/助产专业本科生和应届毕业生的专业认同感形成以及参加护理和助产专业课程的动机。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-10 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4435
Scovia Nalugo Mbalinda, Kamoga Livingstone, Josephine Nambi Najjuma, Aloysius Mubuuke Gonzaga, Derrick Lusota, David Musoke, Samuel Owusu-Sekyere

Introduction: The development of a strong professional identity is influenced by the motivation behind enrolling in a nursing or midwifery programme. Professional identity is a driving force that sustains the commitment of nurses and midwives to nursing/midwifery and their dedication to the well‑being of those they serve. This study evaluated Ugandan students' reasons for enrolling in nursing and midwifery programmes. Furthermore, we investigated the nurse/midwifery practices that support professional identity creation in recent graduates and undergraduate nursing/midwifery students. Methods: A mixed‑method research approach was employed amongst nursing/midwifery students of Makerere University and Mbarara University of Science and Technology and recent nursing/midwifery graduates from Mulago National and Mbarara Regional referral hospitals. We collected quantitative data from 173 participants, and for qualitative data, we conducted six focus group discussions among recent graduates and students of nursing/midwifery. We used descriptive statistics and thematic analysis to analyse the quantitative and qualitative data. Results: Nearly all - 95.4% (165/173) - of the participants were motivated to undertake nursing/midwifery as their programme of study, and 94.2% (163/173) participants identified as nurses/midwives, all with an average score above 3. They also strongly agreed that they took up the programmes because they wanted to learn new things [111/173 (64.2%)] and considered nurses' groups important [68.8% (119/173)]. Participants proposed measures to promote the formation of professional identity among students and graduates, including the improvement of clinical education, the phasing out of certain levels of practice, the empowerment and embedding of ethical principles, recognition and motivation, mentorship, leadership, career guidance and the inclusion of men and challenging of gender stereotypes. Conclusion: Participants were motivated to work in nursing. The ways to promote professional identity included the improvement of clinical education, the phasing out of certain levels of practice, the empowerment and instillation of ethical principles, recognition and motivation, mentorship, leadership, career guidance and male inclusiveness and the challenging of gender stereotypes. Nursing and midwifery leadership needs to provide guidance, mentorship and empowerment; challenge gender stereotypes in nursing/midwifery practice; and give support while advocating for ethical practice.

简介护士或助产士学习护理或助产课程的动机会影响其对专业的强烈认同。职业认同感是护士和助产士致力于护理/助产工作以及为服务对象的福祉奉献的动力。本研究评估了乌干达学生报名参加护理和助产课程的原因。此外,我们还调查了支持应届毕业生和护理/助产专业本科生树立职业认同感的护理/助产实践。研究方法在马凯雷雷大学(Makerere University)和姆巴拉拉科技大学(Mbarara University of Science and Technology)的护理/助产专业学生以及穆拉戈国立医院(Mulago National Hospital)和姆巴拉拉地区转诊医院(Mbarara Regional Referral Hospital)的护理/助产专业应届毕业生中采用了混合方法研究法。我们收集了 173 名参与者的定量数据,并对护理/助产专业的应届毕业生和学生进行了六次焦点小组讨论,以获得定性数据。我们使用了描述性统计和主题分析来分析定量和定性数据。分析结果几乎所有参与者(95.4%,165/173 人)都将护理/助产作为自己的学习课程,94.2%(163/173 人)的参与者认为自己是护士/助产士,平均得分均在 3 分以上。他们还非常同意自己是因为想学习新知识才参加课程的[111/173(64.2%)],并认为护士团体很重要[68.8%(119/173)]。与会者提出了促进学生和毕业生形成专业认同的措施,包括改进临床教育、逐步取消某些级别的实践、赋权和植入道德原则、认可和激励、导师制、领导力、职业指导以及纳入男性和挑战性别陈规定型观念。结论参与者对从事护理工作充满动力。促进职业认同的方法包括改进临床教育、逐步取消某些执业级别、赋权和灌输道德原则、认可和激励、导师制、领导力、职业指导、男性包容和挑战性别陈规定型观念。护理和助产领导层需要提供指导、传帮带和赋权;挑战护理/助产实践中的性别陈规定型观念;在倡导道德实践的同时给予支持。
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引用次数: 0
Heart Failure Care Facilitators and Barriers in Rural Haiti: A Qualitative Study. 海地农村地区心力衰竭护理的促进因素和障碍:定性研究。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-25 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4521
Gene F Kwan, Elizabeth Basow, Benito D Isaac, Darius L Fenelon, Evyrna Toussaint, Dawson Calixte, Michel Ibrahim, Lisa R Hirschhorn, Mari-Lynn Drainoni, Alma Adler, Mary A Clisbee, Gene Bukhman

Background: Heart failure (HF) is a leading cause of hospitalizations in Haiti. However, few patients return for outpatient care. The factors contributing to chronic HF care access are poorly understood. Objective: The purpose of this study is to investigate the facilitators and barriers to accessing care for chronic HF from the patients' perspectives. Methods: We conducted a qualitative descriptive study of 13 patients with HF participating in three group interviews and one individual interview. We recruited patients after discharge from a nongovernmental organization-supported academic hospital in rural Haiti. We employed thematic analysis using emergent coding and categorized themes using the socioecological model. Findings: Facilitators of chronic care included participants' knowledge about the importance of treatment for HF and engagement with health systems to manage symptoms. Social support networks helped participants access clinics. Participants reported low cost of care at this subsidized hospital, good medication accessibility, and trust in the healthcare system. Participants expressedstrong spiritual beliefs, with the view that the healthcare system is an extension of God's influence. Barriers to chronic care included misconceptions about the importance of adherence to medications when symptoms improve and remembering follow-up appointments. Unexpectedly, participants believed they should take their HF medications with food and that food insecurity resulted in missed doses. Lack of social support networks limited clinic access. The nonhealthcare costs associated with clinic visits were prohibitive for many participants. Participants expressed low satisfaction regarding the clinic experience. A barrier to healthcare was the belief that heart disease caused by mystical and supernatural spirits is incurable. Conclusions: We identified several facilitators and barriers to chronic HF care with meaningful implications for HF management in rural Haiti. Future interventions to improve chronic HF care should emphasize addressing misconceptions about HF management and fostering patient support systems for visit and medication adherence. Leveraging local spiritual beliefs may also promote care engagement.

背景:在海地,心力衰竭(HF)是导致住院治疗的主要原因。然而,很少有患者返回医院接受门诊治疗。人们对导致慢性心力衰竭患者就医的因素知之甚少。研究目的本研究旨在从患者的角度出发,调查慢性心力衰竭患者获得护理的促进因素和障碍。方法:我们对 13 名高血压患者进行了定性描述性研究,他们参加了三次小组访谈和一次个人访谈。我们招募了海地农村地区一家非政府组织支持的学术医院的出院患者。我们采用新兴编码法进行主题分析,并使用社会生态模型对主题进行分类。研究结果慢性病护理的促进因素包括参与者对高血压治疗重要性的认识以及参与医疗系统以控制症状。社会支持网络帮助参与者进入诊所。参与者表示,在这家受补贴的医院就医费用低廉、药物可及性好、对医疗系统信任。参与者表达了强烈的精神信仰,认为医疗系统是上帝影响的延伸。慢性病护理的障碍包括对症状改善后坚持服药和记住复诊时间重要性的误解。出乎意料的是,参与者认为他们应该与食物一起服用高血脂药物,而且食物不安全会导致漏服药物。缺乏社会支持网络限制了就诊。与就诊相关的非医疗费用让许多参与者望而却步。参与者对就诊体验的满意度较低。医疗保健的障碍之一是人们认为由神秘和超自然的灵魂引起的心脏病是无法治愈的。结论:我们发现了一些慢性高血压治疗的促进因素和障碍,对海地农村地区的高血压管理具有重要意义。未来改善慢性心房颤动护理的干预措施应强调消除对心房颤动管理的误解,并促进患者就诊和坚持服药的支持系统。利用当地的精神信仰也可促进患者参与治疗。
{"title":"Heart Failure Care Facilitators and Barriers in Rural Haiti: A Qualitative Study.","authors":"Gene F Kwan, Elizabeth Basow, Benito D Isaac, Darius L Fenelon, Evyrna Toussaint, Dawson Calixte, Michel Ibrahim, Lisa R Hirschhorn, Mari-Lynn Drainoni, Alma Adler, Mary A Clisbee, Gene Bukhman","doi":"10.5334/aogh.4521","DOIUrl":"https://doi.org/10.5334/aogh.4521","url":null,"abstract":"<p><p><i>Background:</i> Heart failure (HF) is a leading cause of hospitalizations in Haiti. However, few patients return for outpatient care. The factors contributing to chronic HF care access are poorly understood. <i>Objective:</i> The purpose of this study is to investigate the facilitators and barriers to accessing care for chronic HF from the patients' perspectives. <i>Methods:</i> We conducted a qualitative descriptive study of 13 patients with HF participating in three group interviews and one individual interview. We recruited patients after discharge from a nongovernmental organization-supported academic hospital in rural Haiti. We employed thematic analysis using emergent coding and categorized themes using the socioecological model. <i>Findings:</i> Facilitators of chronic care included participants' knowledge about the importance of treatment for HF and engagement with health systems to manage symptoms. Social support networks helped participants access clinics. Participants reported low cost of care at this subsidized hospital, good medication accessibility, and trust in the healthcare system. Participants expressedstrong spiritual beliefs, with the view that the healthcare system is an extension of God's influence. Barriers to chronic care included misconceptions about the importance of adherence to medications when symptoms improve and remembering follow-up appointments. Unexpectedly, participants believed they should take their HF medications with food and that food insecurity resulted in missed doses. Lack of social support networks limited clinic access. The nonhealthcare costs associated with clinic visits were prohibitive for many participants. Participants expressed low satisfaction regarding the clinic experience. A barrier to healthcare was the belief that heart disease caused by mystical and supernatural spirits is incurable. <i>Conclusions:</i> We identified several facilitators and barriers to chronic HF care with meaningful implications for HF management in rural Haiti. Future interventions to improve chronic HF care should emphasize addressing misconceptions about HF management and fostering patient support systems for visit and medication adherence. Leveraging local spiritual beliefs may also promote care engagement.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":"90 1","pages":"60"},"PeriodicalIF":2.6,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11428663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142330506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mobile Critical Care in Resource-Limited Settings: An Unmet Need. 资源有限地区的移动重症监护:尚未满足的需求。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-19 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4506
Varun U Shetty

Care of the critically ill in resource-limited areas, inside or outside the intensive care unit (ICU), is indispensable. Murthy and Adhikari noted that about 70% of patients in low-middle income (LMIC) areas could benefit from good critical care. Many patients in resource-limited settings still die before getting to the hospital. Investing in capacity building by strengthening and expanding ICU capability and training intensivists, critical care nurses, respiratory therapists, and other ICU staff is essential, but this process will take years. Also, having advanced healthcare facilities that are still far from remote areas will not do much to alleviate distance and mode of transportation as barriers to achieving good critical care. This paper discusses the importance of mobile critical care units (MCCUs) in supporting and enhancing existing emergency medical systems. MCCUs will be crucial in addressing critical delays in transportation and time to receive appropriate lifesaving critical care in remote areas. They are incredibly versatile and could be used to transfer severely ill patients to a higher level of care from the field, safely transfer critically ill patients between hospitals, and, sometimes, almost more importantly, provide standalone short-term critical care in regions where ICUs might be absent or immediately inaccessible. MCCUs should not be used as a substitute for primary care or to bypass readily available services at local healthcare centers. It is essential to rethink the traditional paradigm of 'prehospital care' and 'hospital care' and focus on improving the care of critically ill patients from the field to the hospital.

在资源有限的地区,重症监护室(ICU)内外的危重病人护理是不可或缺的。Murthy 和 Adhikari 指出,在中低收入(LMIC)地区,约有 70% 的病人可以从良好的重症监护中受益。在资源有限的环境中,许多病人在送往医院之前就已经死亡。投资能力建设,加强和扩大重症监护室的能力,培训重症监护医生、重症监护护士、呼吸治疗师和其他重症监护室工作人员至关重要,但这一过程需要数年时间。此外,即使拥有先进的医疗设施,但这些设施距离偏远地区仍然很远,这并不能有效缓解距离和交通方式对实现良好重症监护的阻碍。本文讨论了流动重症监护病房(MCCU)在支持和加强现有紧急医疗系统方面的重要性。移动危重症监护病房对于解决偏远地区交通和时间上的严重延误以及接受适当的救生危重症护理至关重要。它们的用途非常广泛,可用于将重症患者从野外转运到更高级别的医疗机构,在医院之间安全转运重症患者,有时,几乎更重要的是,在重症监护室可能不存在或无法立即到达的地区提供独立的短期重症监护。重症监护病房不应被用来替代初级医疗服务或绕过当地医疗中心的现有服务。必须重新思考 "院前救护 "和 "医院救护 "的传统模式,重点改善从现场到医院的危重病人救护。
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引用次数: 0
Assessment of SADC Countries' National Adaptation Planning Health Impacts Inclusion: A Thorough Review. 南部非洲发展共同体国家适应规划健康影响纳入评估:彻底审查。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-18 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4458
Renate Meyer, Caradee Wright, Hanna-Andrea Rother

Background: The impacts of climate change are recognised as a key challenge of the 21st century. By 2030, Sub-Saharan Africa is projected to have the globally highest burden of disease due to climate change. Objectives: This study aims to evaluate the strengths and weaknesses of the National Adaptation Plans (NAPs) of the Southern African Development Community (SADC), a sub-region under-represented at a global level, in addressing current and future climate change-related health impacts. It specifically assesses the NAPs of Botswana, Mozambique, Namibia, South Africa, and Zimbabwe. Methods: A thorough review was conducted, analysing articles, government reports, and national communications related to NAPs and climate change health outcomes in the selected countries. Sources were evaluated against pre-defined inclusion and exclusion criteria. Main findings: All five countries prioritised health in their NAPs; however, health departments were excluded from assessments in two of the countries. Although health surveillance and early warning systems were included in the NAPs, there was limited evidence of their integration into broader climate, health, economic, and labour policies. National climate change focal points were identified, but governance and implementation at district and local levels were not well-documented. This review highlighted a need for greater inclusion of Indigenous and locally led knowledge. Common barriers identified included the lack of data with appropriate frequency and scale. Governance and implementation difficulties were also identified in all five countries; these difficulties included both a lack of coordination and a lack of institutional capacity. These challenges, especially a lack of political will to address the compound impacts of altered climate and health on all earth systems, are also found at the regional level. Conclusions: National strategies and implementation programs in SADC countries need to be agile in their ability to scale and adapt, yet they also need to include measurable actions and timeframes. Given the shared climate and health trends and the interconnected socio-economic, environmental, and political landscape, there is significant potential for regional coordination to address cross-border climate change impacts and to optimise resource use.

背景:气候变化的影响被认为是 21 世纪的主要挑战。预计到 2030 年,撒哈拉以南非洲地区因气候变化造成的疾病负担将居全球之首。目标:本研究旨在评估南部非洲发展共同体 (SADC) 国家适应计划 (NAP) 在应对当前和未来与气候变化相关的健康影响方面的优缺点。本报告特别评估了博茨瓦纳、莫桑比克、纳米比亚、南非和津巴布韦的国家适应计划。方法:对所选国家与国家行动方案和气候变化健康结果相关的文章、政府报告和国家信息通报进行了全面审查和分析。根据预先确定的纳入和排除标准对资料来源进行了评估。主要发现:所有五个国家都在其国家行动方案中将健康列为优先事项;但是,其中两个国家的卫生部门被排除在评估之外。虽然国家行动方案中包含了健康监测和预警系统,但将其纳入更广泛的气候、健康、经济和劳动政策的证据有限。国家气候变化协调中心已经确定,但地区和地方一级的治理和实施情况却没有得到很好的记录。本次审查强调需要更多地纳入土著和地方主导的知识。发现的共同障碍包括缺乏适当频率和规模的数据。在所有五个国家都发现了治理和实施方面的困难;这些困难包括缺乏协调和缺乏机构能力。这些挑战,尤其是缺乏政治意愿来应对气候和健康变化对所有地球系统的复合影响,在地区层面也同样存在。结论:南部非洲发展共同体(SADC)国家的国家战略和实施计划需要具有灵活的扩展和适应能力,但也需要包括可衡量的行动和时间框架。鉴于共同的气候和健康趋势以及相互关联的社会经济、环境和政治格局,区域协调在应对跨境气候变化影响和优化资源利用方面具有巨大潜力。
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引用次数: 0
Predictors of Adherence to Antiretroviral Therapy among People Living with HIV in Northern Egypt. 埃及北部艾滋病病毒感染者坚持抗逆转录病毒疗法的预测因素。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-16 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4491
Mona Magdy, Adel Zaki, Sherif Omar Osman, Ekram W Abd El-Wahab, Asmaa Abd Elhameed

Background: Adherence to medications is a crucial factor in achieving the best therapeutic outcomes for patients who have human immunodeficiency virus (HIV). Little is known about the rate and predictors of adherence to antiretroviral therapy (ART) in Egypt. Objectives: To assess the degree of adherence to ART among people living with HIV/AIDS (PLWHA) in Egypt and to explore the predictors of non-adherence. Methods: A cross-sectional study was conducted from January 2021 to December 2021 on 785 PLWHA attending an ART clinic at the main fever hospital in Alexandria, Egypt. Data collection was done using an interviewing questionnaire and pharmacy database records. Multivariate logistic regression analysis was done to identify the predictors of adherence to ART. Results: The overall adherence rate to ART among the study subjects was 66.7%. Female sex (Adjusted Odds Ratio [95% CI]: 1.73 [1.01-2.96]), intravenous drug use (AOR [95% CI]: 2.87 [1.27-6.49]), fair satisfaction with the health service at ART clinics (OR [95% CI]: 1.86 [1.27-2.73]) appeared as independent predictors of poor adherence. Conclusion: The degree of adherence to ART among PLWHA in Egypt is noticeably high, although it was influenced by several patient-, healthcare-, and community-related factors. This work provides an accurate, standardized tool to measure adherence and identify factors that contribute to non-adherence.

背景:坚持用药是人类免疫缺陷病毒(HIV)患者获得最佳治疗效果的关键因素。在埃及,人们对坚持抗逆转录病毒疗法(ART)的比例和预测因素知之甚少。研究目的评估埃及艾滋病毒/艾滋病感染者(PLWHA)坚持抗逆转录病毒疗法的程度,并探讨不坚持治疗的预测因素。研究方法2021 年 1 月至 2021 年 12 月期间,对在埃及亚历山大主要发热医院抗逆转录病毒疗法门诊就诊的 785 名艾滋病毒/艾滋病感染者进行了横断面研究。数据收集采用访谈问卷和药房数据库记录。采用多变量逻辑回归分析确定坚持抗逆转录病毒疗法的预测因素。结果显示研究对象坚持抗逆转录病毒疗法的总体比例为 66.7%。女性(调整比值比 [95%CI]:1.73 [1.01-2.96])、静脉注射毒品(AOR [95%CI]:2.87 [1.27-6.49])、对抗病毒疗法诊所医疗服务的满意度一般(OR [95%CI]:1.86 [1.27-2.73])是不良依从性的独立预测因素。结论埃及 PLWHA 抗逆转录病毒疗法的依从性明显较高,但受到患者、医疗保健和社区相关因素的影响。这项工作提供了一种准确、标准化的工具来衡量依从性并识别导致不依从的因素。
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引用次数: 0
Is there an Association between Dietary Micronutrients Intake and Bone Fractures among Malaysian Reproductive-Age Women? The PURE Malaysia Study. 马来西亚育龄妇女的膳食微量营养素摄入量与骨折之间是否存在关联?马来西亚 PURE 研究。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-04 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4445
Zaleha Md Isa, Nur Atiqah Mohd Ahwan, Noor Hassim Ismail, Rosnah Ismail, Azmi Mohd Tamil, Mohd Hasni Jaafar, Nafiza Mat-Nasir, Nik Munirah Nik Mohd Nasir, Nurul Hafiza Ab Razak, Khairul Hazdi Yusof

Background: Bone fractures represent a significant health issue and impose a considerable burden on healthcare systems globally. However, data pertaining to bone fractures, especially among reproductive-age women in Malaysia, are very limited. Micronutrients like calcium, magnesium and phosphorus play vital roles in bone health, influencing bone mineral density and fracture risk. The objective of this study was to determine the prevalence of bone fractures among reproductive-age women and the association with dietary micronutrient intakes. Methods: In this cross-sectional study, a total of 1,730 participants of reproductive-age women from the Malaysia Prospective Urban and Rural Epidemiological (PURE) study were recruited. The participants' dietary intakes were assessed using a validated semi-quantitative food frequency questionnaire (FFQ). Selected micronutrients in the participants' diets were calculated using the Malaysian food composition and the US Department of Agriculture food composition databases. The association between micronutrient intakes, comorbidities and physical activity levels with bone fractures were evaluated to identify predictors of bone fractures among reproductive-age women. Results: The prevalence of bone fractures among Malaysian reproductive-age women was low (3.7%). The multiple logistic regression analysis showed that none of the micronutrients was associated with bone fractures. However, factors of diabetes and passive smoking in this study showed 2.6- and 4.0-times-higher odds of having bone fractures, respectively (AOR 2.580; 95% CI: 1.173-5.672) and (AOR 4.012; 95% CI: 2.265-7.107). Conclusions: It was found that the majority of women in this study were taking lower micronutrient intakes of calcium, magnesium, and vitamin K than the Malaysia recommended nutrient intakes (RNI). Although this study showed that a low micronutrient intake is not significantly associated with bone fractures, it is recommended that future studies focus on controlled trials or prospective data analyses to establish causal relationships and the optimal micronutrient requirements for maintaining strong and healthy bones in women of reproductive age.

背景:骨折是一个重大的健康问题,给全球医疗保健系统造成了相当大的负担。然而,有关骨折的数据非常有限,尤其是马来西亚育龄妇女的骨折数据。钙、镁和磷等微量营养素对骨骼健康起着至关重要的作用,影响着骨矿物质密度和骨折风险。本研究的目的是确定育龄妇女骨折的发生率以及与膳食微量营养素摄入量的关系。研究方法这项横断面研究从马来西亚前瞻性城乡流行病学(PURE)研究中招募了 1730 名育龄妇女。研究人员使用经过验证的半定量食物频率问卷(FFQ)评估了她们的膳食摄入量。参与者膳食中的部分微量营养素是通过马来西亚食品成分和美国农业部食品成分数据库计算得出的。评估了微量营养素摄入量、合并症和体力活动水平与骨折之间的关系,以确定育龄妇女骨折的预测因素。结果显示马来西亚育龄妇女的骨折发生率较低(3.7%)。多元逻辑回归分析表明,没有一种微量营养素与骨折有关。然而,在本研究中,糖尿病和被动吸烟因素导致骨折的几率分别比其他因素高 2.6 倍和 4.0 倍(AOR 2.580;95% CI:1.173-5.672)和(AOR 4.012;95% CI:2.265-7.107)。结论本研究发现,大多数妇女的钙、镁和维生素 K 的微量营养素摄入量低于马来西亚推荐的营养素摄入量(RNI)。尽管这项研究表明,微量营养素摄入量低与骨折并无明显关联,但建议今后的研究应侧重于对照试验或前瞻性数据分析,以确定因果关系以及育龄妇女维持强健骨骼的最佳微量营养素需求量。
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引用次数: 0
Global Community Health Screening and Educational Intervention for Early Detection of Cardiometabolic Renal Disease. 早期发现心脏代谢性肾病的全球社区健康检查和教育干预。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-08-21 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4497
Natalie L Nabaty, Tushar Menon, Garrett Trang, Aditya Vijay, Lama Chogyal, Renzo Cataldo, Navin Govind, Pankaj Jain, Priti Singh, Navaz Dolasa, Mandeep Sahani, Prakash Deedwania, Krishnaswami Vijayaraghavan

The global burden of cardiometabolic renal disease is increasing, particularly in underserved communities. Twinepidemic Inc.'s Galvanize Healthy Living program conducts community screenings, risk assessments, and educational interventions globally. We screened 1209 subjects for cardiovascular-kidney-metabolic syndrome, assessing their disease knowledge and self-confidence. Mean age was 50, with 65% females and 35% males. Imaging post-risk assessment revealed abnormalities: EKG (16%), echocardiogram (10%), carotid plaque (9%), ABI (2.5%), and eye exam (3.6%, including 8 retinopathies, 14 cataracts). New onset DM was found in 8%, prediabetes in 18.5%, High LDL in 4.2%, low HDL in 40.2%, high triglycerides in 13.1%, and abnormal BP in 38%. In addition, 18.2% were reclassified to a higher category of risk levels after imaging. Significant improvements in knowledge and self-empowerment (all p < 0.001) were seen after educational interventions. This study underscores early risk assessment's potential to enhance health outcomes globally for underserved populations, validating POC imaging and emphasizing the role of accessible care and education in patient engagement and empowerment.

全球心血管代谢性肾病的负担日益加重,尤其是在服务不足的社区。双流行病学公司的 Galvanize 健康生活计划在全球范围内开展社区筛查、风险评估和教育干预活动。我们对 1209 名受试者进行了心血管-肾脏-代谢综合征筛查,评估了他们的疾病知识和自信心。平均年龄为 50 岁,其中女性占 65%,男性占 35%。风险评估后的影像学检查显示存在异常:心电图(16%)、超声心动图(10%)、颈动脉斑块(9%)、ABI(2.5%)和眼科检查(3.6%,包括 8 例视网膜病变和 14 例白内障)。发现新发糖尿病的占 8%,糖尿病前期的占 18.5%,高低密度脂蛋白的占 4.2%,低高密度脂蛋白的占 40.2%,高甘油三酯的占 13.1%,血压异常的占 38%。此外,18.2%的人在成像后被重新归类为更高风险等级。经过教育干预后,患者的知识水平和自我赋权能力都有了显著提高(P 均小于 0.001)。这项研究强调了早期风险评估在全球范围内改善服务不足人群健康状况的潜力,验证了 POC 成像技术,并强调了无障碍护理和教育在患者参与和赋权方面的作用。
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引用次数: 0
An Umbrella Review of Meta-Analyses Evaluating Associations between Human Health and Exposure to Major Classes of Plastic-Associated Chemicals. 对评估人类健康与接触主要类别塑料相关化学品之间关系的荟萃分析综述。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-08-19 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4459
Christos Symeonides, Edoardo Aromataris, Yannick Mulders, Janine Dizon, Cindy Stern, Timothy Hugh Barker, Ashley Whitehorn, Danielle Pollock, Tania Marin, Sarah Dunlop
<p><p><i>Background:</i> Epidemiological research investigating the impact of exposure to plastics, and plastic-associated chemicals, on human health is critical, especially given exponentially increasing plastic production. In parallel with increasing production, academic research has also increased exponentially both in terms of the primary literature and ensuing systematic reviews with meta-analysis. However, there are few overviews that capture a broad range of chemical classes to present a state of play regarding impacts on human health. <i>Methods:</i> We undertook an umbrella review to review the systematic reviews with meta-analyses. Given the complex composition of plastic and the large number of identified plastic-associated chemicals, it was not possible to capture all chemicals that may be present in, and migrate from, plastic materials. We therefore focussed on a defined set of key exposures related to plastics. These were microplastics, due to their ubiquity and potential for human exposure, and the polymers that form the matrix of consumer plastics. We also included plasticisers and flame retardants as the two classes of functional additive with the highest concentration ranges in plastic. In addition, we included bisphenols and per- and polyfluoroalkyl substances (PFAS) as two other major plastic-associated chemicals with significant known exposure through food contact materials. Epistemonikos and PubMed were searched for systematic reviews with meta-analyses, meta-analyses, and pooled analyses evaluating the association of plastic polymers, particles (microplastics) or any of the selected groups of high-volume plastic-associated chemicals above, measured directly in human biospecimens, with human health outcomes. <i>Results:</i> Fifty-two systematic reviews were included, with data contributing 759 meta-analyses. Most meta-analyses (78%) were from reviews of moderate methodological quality. Across all the publications retrieved, only a limited number of plastic-associated chemicals within each of the groups searched had been evaluated in relevant meta-analyses, and there were no meta-analyses evaluating polymers, nor microplastics. Synthesised estimates of the effects of plastic-associated chemical exposure were identified for the following health outcome categories in humans: birth, child and adult reproductive, endocrine, child neurodevelopment, nutritional, circulatory, respiratory, skin-related and cancers. Bisphenol A (BPA) is associated with decreased anoclitoral distance in infants, type 2 diabetes (T2D) in adults, insulin resistance in children and adults, polycystic ovary syndrome, obesity and hypertension in children and adults and cardiovascular disease (CVD); other bisphenols have not been evaluated. Phthalates, the only plasticisers identified, are associated with spontaneous pregnancy loss, decreased anogenital distance in boys, insulin resistance in children and adults, with additional associations between certain
初级研究的优先事项以及随后的系统性审查可包括微塑料和纳米塑料以及新出现的令人担忧的塑料相关化学品,如双酚类似物、替代增塑剂和阻燃剂。在化学品监管方面,我们建议在进入市场时不能假定塑料相关化学品对人体的安全性。因此,我们建议在产品投放市场之前,对所有与塑料相关的化学品进行独立、系统的危害测试。此外,由于实验室测试在预测塑料对人体的危害方面存在局限性,因此必须在产品上市后进行独立、系统的生物监测和流行病学研究,以发现潜在的意外危害。
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引用次数: 0
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