Annals of Global Health最新文献

Background: Lack of policy prioritization of surgical, obstetric, trauma and anesthesia (SOTA) care in South and Southeast Asian countries could be a potential contributor to limited access to care. Objective: To assess the SOTA care prioritization in National Health Policies, Strategies, and Plans (NHPSPs). Methods: We analyzed NHPSPs from twelve South and Southeast Asian countries. These documents are considered the most important health‑related policy statements. Bangladesh was excluded due to a lack of English translations. We searched sixteen electronic documents for a predefined list of keywords. The list included 52 keywords related to SOTA care and 7 keywords unrelated to SOTA care (used as a control). We used the keyword frequency (mentions per keyword or MPK) as a measure to compare prioritization between SOTA care and non‑SOTA care. We further categorized the SOTA care keywords into five different Lancet Commission on Global Surgery (LCoGS) domains and eight subgroups. Findings: Across twelve NHPSPs, MPK value for SOTA care was 54.09 compared with 202.86 for non‑SOTA, with eight NHPSPs having lower MPK values for SOTA care than non‑SOTA keywords. Four NHPSPs had no mentions related to SOTA care financing and information management. Pediatric surgery and anesthesia were among the neglected subgroups. Conclusion: The analysis of South and Southeast Asian NHPSPs suggests that SOTA care issues are not prioritized in most countries. Pathways to greater policy attention include integrating SOTA care into ongoing health policy‑making and planning efforts and developing and implementing specific national SOTA care plans.

Background: Metabolic diseases such as hypertension and diabetes are increasingly recognized as not just medical issues, but as complex conditions influenced by various factors. Objectives: This study aimed to explore the association between food insecurity (FI) and hypertension and diabetes and how socioeconomic status influences this relationship. Methods: Based on a cross‑sectional study of 1,820 participants conducted in Maputo City, FI was measured using a modified version of the US Department of Agriculture scale; metabolic diseases were assessed using self‑reports of the actual diagnoses, and data were analyzed through multinomial regression and interaction terms. Results: The findings revealed significant links between FI, socioeconomic status, hypertension and diabetes. Socioeconomic status had a clear influence on the association between FI and hypertension but showed a nuanced influence on diabetes. Specifically, regarding diabetes, the heads of households with a higher socioeconomic position were more likely to have this health condition than their counterparts with a lower socioeconomic position. Conclusions: The study underscores the complex interplay between FI and socioeconomic status in influencing the risk of metabolic diseases. Addressing FI and improving socioeconomic status may be crucial steps in mitigating the risk of hypertension and diabetes among vulnerable populations, emphasizing the importance of a holistic approach to health promotion and disease prevention.

Background: African research capacity is challenged by insufficient infrastructure to solicit and manage grants from local and international funding agencies. Objective: The manuscript provides an overview and discusses lessons learned about the pioneering role of the Mozambique Institute for Health Education and Research (MIHER) as the first research support center (RSC) in supporting the management of research grants in Mozambique, emphasizing its impact on research capacity development. Methods: Using mixed methods, data were comprehensively collected to identify MIHER's primary achievements from 2010 to 2023. The activities took place in four public universities, five training institutions for healthcare workers, and 40 public healthcare units in Mozambique. Findings: MIHER had partnership contracts with over 35 external institutions, and supported the design and implementation of one doctoral program and five masters' degree programs at three public universities. Over 70% of the 128 MSc and three Ph.D. degree recipients have gone on to become lecturers at Mozambique's public universities or are working in Mozambique's public health system. Over 9,000 lecturers and healthcare workers participated in MIHER's 261 research capacity development workshops. MIHER assisted in writing and implementing 98 research grants, amassing $29,923,197 in extramural support. Of 170 publications generated, 89% were indexed in PubMed. African researchers served as first or last author in 55% and 34% of these publications, respectively; Mozambicans were first and last authors in 44% and 23% of the articles, respectively. Two research laboratories were rehabilitated. Investments in information and communication technology also fostered training and mentorship. Conclusions: MIHER has emerged as a leading RSC of Excellence, fostering synergies and promoting a quality research culture in Mozambique, fueled in part, by its ability to identify and incorporate key collaborations. MIHER is a successful example of an RSC that can make the difference in resource‑limited settings to enable research resource mobilization, evidence-based health care delivery and policy design.

Introduction: Despite the broad improvement in air quality, air pollution remains a major leading global risk factor for ill health and deaths each year. Air pollution has a significant impact on both health and economic growth in Africa. This paper reviews the health impacts of air pollution and the benefits of air pollution mitigation and prevention on climate change. Methods: We conducted a narrative review and synthesized current literature on the health impact of air pollution in the context of changing climate in Africa. Results: Particulate matter (PM_2.5) concentrations in Africa pose significant health risks due to various sources, including household fuels and industrial emissions. Limited air quality monitoring hampers accurate assessment and public health planning. Africa's rapid urbanization exacerbates air pollution, impacting vulnerable populations disproportionately. Renewable energy adoption and improved monitoring infrastructure are crucial for mitigating air pollution's economic and health impacts. Recommendations include adopting air quality standards, identifying pollution sources, and prioritizing interventions for vulnerable groups. Integrating renewable energy into development plans is essential for sustainable growth. African leaders must prioritize environmental policies to safeguard public health amid ongoing industrialization. Conclusions: Air pollution prevention remains a vital concern that requires leaders to engage stakeholders, and other opinion leaders in society. African leaders should proactively explore new avenues to integrate non‑polluting renewable energy sources such as solar power, wind and hydropower into their national development plans.

Background: Smoking is the primary risk factor for tracheal, bronchus, and lung (TBL) cancer. Objective: This study aims to explore the epidemiological trends of smoking-attributable TBL cancer from 1990 to 2021. Methods: Mortality and disability-adjusted life-years (DALYs) data for smoking-related TBL cancer from 1990 to 2021 were sourced from the Global Burden of Disease Study (GBD) 2021. Estimated annual percentage changes (EAPCs) were calculated to evaluate trends in age-standardized mortality rates (ASMRs) and age-standardized DALY rates (ASDRs). Additionally, the relationship between disease burden, EAPCs, and the sociodemographic index (SDI) was assessed. Findings: Compared with 1990, both the mortality and DALYs due to smoking-related TBL cancer substantially increased by 2021. However, during this period, ASMR [EAPC: -0.97; 95% confidence interval (CI): -1.05 to -0.89] and ASDR (EAPC: -1.29; 95% CI: -1.37 to -1.22) demonstrated a downward trend. ASMR and ASDR in females were consistently lower than in males. In 2021, East Asia had the highest ASMR, while Central Europe recorded the highest ASDR, with Greenland exhibiting the highest ASMR and ASDR at the national level. Nationally, ASMR for smoking-related TBL cancer in 2021 showed a positive correlation with SDI, while the EAPC of both ASMR and ASDR from 1990 to 2021 displayed a negative correlation with SDI. Furthermore, in 2021, the greatest number of deaths from smoking-related TBL cancer occurred in individuals aged 70-74, while DALYs were highest in the 65-69 age group. Conclusions: The burden of smoking-related TBL cancer varies across age, sex, geography, and SDI regions. Tailored public health interventions aligned with these epidemiological characteristics are essential for alleviating the disease burden.

Background: While cancer is a leading cause of death worldwide, significant disparities exist in care access in low‑ and middle‑income countries (LMICs). In Liberia, screening and treatment for anal cancers remain limited, and are exacerbated among vulnerable groups, including men who have sex with men (MSM). Screen‑triage‑treat models for cancerous lesions have been successful in reducing cervical cancer mortality, but the feasibility of this approach has not been studied for anal cancers in a low‑resource context. Objective: The aim of this study is to determine the feasibility of implementing a screen‑triage‑treat model for anal high‑grade squamous intraepithelial lesions (aHSIL) among MSM in Liberia. Methods: This descriptive study represented a collaboration between Stop AIDS in Liberia (SAIL) and health institutions in Liberia and the USA. MSM and transgender participants were recruited through convenience sampling with SAIL peer‑educators. A survey validated by SAIL experts assessed demographics and sexual risk factors. Participants underwent anal self‑swabbing for high‑risk human papillomavirus (HPV) and offered human immunodeficiency virus (HIV) testing. Those with positive results were offered a screen‑triage‑treat model through high‑resolution anoscopy (HRA) and infrared coagulation (IRC). Data were cleaned and analyzed in SPSS. Findings: Among 110 participants, most were single (n = 94, 88%) and without formal employment (n = 21, 75%). Participants engaged in regular anal (n = 64, 60%), oral (n = 62, 58%), and receptive sex (n = 58, 54%), and sex with women (n = 51, 48%). Nearly 20% of participants reported being HIV positive (n = 21). In all, 50 participants (45%) tested positive for anal high‑risk HPV, 34 (68%) elected to undergo HRA, and 10 (84%) were treated with IRC. Of those who underwent HRA, 75% tested HIV positive. Conclusions: Our findings suggest that a screen‑triage‑treat model presents a feasible option to identify and reduce the incidence of anal cancer among MSM in Liberia. The screen‑triage‑treat model, with proven success in management of cervical dysplasia, may be a viable option to treat aHSIL for anal cancer prevention in LMICs.

Background: In 2014, the Faculty of Health Sciences at Walter Sisulu University introduced a 20‑week long integrated longitudinal clinical clerkship (ILCC) rotation block as part of its commitment to community‑based education and social responsiveness, with the goal of ensuring that the curriculum is updated to align with the contemporary health system challenges in South Africa. Aim: To explore whether medical student participants underwent social and personal transformative learning in understanding complex societal health needs during their integrated longitudinal community clerkship program. Methods: This was an exploratory qualitative research study conducted among 113 5^th year medical students based at 8 selected hospitals during their 20‑week‑long community clerkship. Data were collected through six focus group discussions, complemented by data from reflective learning journal entries. Audio recordings were transcribed verbatim and merged with complementary data for thematic analysis in NVivo Version 13®. Results: Adaptation challenges, improved social relations, coping with work demands, acquisition of relevant knowledge and skills, perceived inadequate support from the training institution and perceived lengthy programme duration emerged as key themes and were linked to personal and social transformation. Conclusion: Personal and social transformation may have transpired amongst the student participants, as demonstrated by the observed thematic consistency between data sources. Further complementary studies are required to assess whether there was a shift in students' understanding of community health needs and how the ILCC may have assisted the students in responding to community needs to have a comprehensive conclusion on whether the ILCC can be a tool for transformative learning.

Background: Experiential learning activities help students prepare for their future careers by providing opportunities for hands‑on practice experiencing real‑world scenarios. Innovations in technology can facilitate experiential learning and cross‑cultural connections for large groups of students in multiple global settings through a virtual platform. However, designing these opportunities with diverse groups of students for a virtual environment can be challenging. Objective: The purpose of this paper is to highlight three examples of innovative virtual experiential learning initiatives that were developed and implemented by the Global Health Program of the Association of Pacific Rim Universities (APRU), a non‑profit network of 60+ leading research universities in the Asia‑Pacific. Findings: We have leveraged the expertise of our wide network to enhance student learning through the purposeful design of virtual educational experiences centered around pedagogical approaches that emphasize active learning, self‑reflection, and knowledge exchange with people from other cultures and disciplines. The annual global health joint virtual courses, the annual APRU Virtual Global Health Case Competition, and the APRU Mini Certificate foster meaningful engagement with other students and experts in the field, expanding the lens of students to foster an increased awareness and appreciation of the diversity of perspectives represented in an international network such as APRU. These allow students to practice real‑world application of knowledge gained in a traditional didactic classroom setting. Conclusions: The benefits of virtual experiential learning to students greatly outweigh the challenges in the design and implementation of such programs. While relatively short‑term, these virtual initiatives have had a demonstrable impact on student participants. Such programs can enhance student learning and provide cost‑effective ways to allow large international cohorts to experience global experiential learning.

Importance: The lack of information on exposure of opencast mineworkers to solar ultraviolet radiation, a group I carcinogen, was addressed. The feasibility of using electronic dosimeters in the determination of exposure to solar ultraviolet radiation was investigated. Objective: The objective of the study was to determine the feasibility of measuring the occupational exposure of opencast mineworkers to solar ultraviolet radiation using electronic dosimeters. Design: The study followed a cross‑sectional design. Setting: Measurements were carried out at two opencast diamond mining operations hereafter referred to as site A and B, located in the Karas region of Namibia. Participants: Workers from all four outdoor occupations (bedrock, engineering, metallurgy and security) were recruited to participate in the study. Measurements: The study was conducted over four days at each site during winter (site A: 28 June to 4 July 2018 and site B: 6-11 July 2018) in the Karas region of Namibia with 28 consenting workers taking part. The AlGaN photodiode‑based electronic dosimeters were worn above clothing on the dorsal wrists (one) and two placed on the horizontal, unshaded area from 08:00 to 16:00 for the measurement of personal and ambient solar ultraviolet radiation, respectively. Historical meteorological data for the measurement period were obtained from Solcast and Ozone Monitoring Instrument (OMI) NASA. Results: Overall, clear skies and surface reflectivity of 0.19 were observed for both study sites. The mean ultraviolet indices were 2.43 (0.06-4.51) and 2.24 (0.09-4.88) for site A and B, respectively. Findings of valid measurements from nine participants showed the mean total daily personal solar ultraviolet radiation exposure of 1.9 ± 1.0 (1.01-1.57) standard erythemal dose (SED) for site A and 3.4 ± 2.6 (3.39-7.28) SED for site B. Conclusions and Relevance: Personal solar ultraviolet radiation exposure above the occupational exposure limit (OEL) demonstrated the need to include the winter season in planning for protective measures for skin and eyes, since workers are at risk of excessive exposure to solar ultraviolet radiation.

Students often seek opportunities to enrich their classroom learning. Providing students the chance to engage in research studies or global health projects allows for experiential enrichment. However, the impact on partners and partner sites, financial implications, and equity of student opportunity, as well as the logistical burden potentially placed on multiple parties, all need to be considered. If challenges are minimized, students can make meaningful contributions to projects, be a catalyst for partner engagement, and allow for formative learning.